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Items 1 to 29 of about 29
1. Kakutani K, Doita M, Nishida K, Miyamoto H, Kurosaka M: Radiculopathy due to malignant melanoma in the sacrum with unknown primary site. Eur Spine J; 2008 Sep;17 Suppl 2:S271-4
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  • Melanoma is an interesting tumor, showing the appearance of metastasis without any trace of its primary lesion.
  • Plain radiograph, computed tomography scan, and magnetic resonance imaging revealed a destructive lesion in the sacrum and left ilium, which infiltrated the spinal canal and sacroiliac joint.
  • The tumor cells were immunoreactive for HMB-45.
  • The pathological diagnosis was malignant melanoma.
  • Following radiotherapy and chemotherapy, the severe buttock pain disappeared and the patient was able to walk without impediment.
  • However the patient died nine months after initial diagnosis.
  • Malignant melanoma in the sacrum with an unknown primary site, showing S1 radiculopathy is reported for the first time.
  • The melanoma could have been a metastatic tumor of the sacrum, although the primary site was not detected.
  • Thus treatment of patients with spinal metastasis of melanoma is an important challenge for orthopedic surgeons.
  • [MeSH-minor] Back Pain / etiology. Back Pain / pathology. Back Pain / physiopathology. Disease Progression. Drug Therapy. Fatal Outcome. Humans. Ilium / pathology. Ilium / radiography. Magnetic Resonance Imaging. Male. Middle Aged. Polyradiculopathy / etiology. Polyradiculopathy / pathology. Polyradiculopathy / physiopathology. Radiotherapy. Sacroiliac Joint / pathology. Sacroiliac Joint / radiography. Spinal Canal / pathology. Spinal Canal / radiography. Tomography, X-Ray Computed. Treatment Failure. Urination Disorders / etiology. Urination Disorders / pathology. Urination Disorders / physiopathology

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  • [Cites] Melanoma Res. 2000 Feb;10(1):78-80 [10711643.001]
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  • (PMID = 18075762.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2525896
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2. Saab R, Rao BN, Rodriguez-Galindo C, Billups CA, Fortenberry TN, Daw NC: Osteosarcoma of the pelvis in children and young adults: the St. Jude Children's Research Hospital experience. Cancer; 2005 Apr 01;103(7):1468-74
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  • RESULTS: Among 442 patients with osteosarcoma, 19 patients (4%) had high-grade tumors arising in the pelvic bones, including the ilium in 15 patients, the pubis in 2 patients, and the sacrum in 2 patients.
  • The median patient age at diagnosis was 16.8 years.
  • Four tumors were secondary to radiation therapy.
  • Five patients had metastases in the lung (n = 4 patients) or bone (n = 1 patient) at diagnosis.
  • The median greatest tumor dimension for the 13 tumors with known size was 10 cm.
  • Of the three patients who survived disease-free, one patient underwent complete resection, one patient underwent incomplete resection (nonviable tumor at the soft tissue margin) with a good response to chemotherapy, and one patient with a sacral tumor underwent radiotherapy only for local control.
  • All patients with metastatic disease at diagnosis died.
  • New therapeutic approaches are needed.
  • [MeSH-major] Osteosarcoma / diagnosis
  • [MeSH-minor] Adolescent. Adult. Child. Female. Humans. Male. Pelvic Neoplasms / diagnosis. Pelvic Neoplasms / therapy. Prognosis. Retrospective Studies. Treatment Outcome

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  • [Copyright] Copyright 2005 American Cancer Society.
  • (PMID = 15739209.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R25 CA023944; United States / NCI NIH HHS / CA / CA-21765; United States / NCI NIH HHS / CA / CA-23099
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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3. Okada K, Hasegawa T, Yokoyama R, Beppu Y, Itoi E: Osteosarcoma with cytokeratin expression: a clinicopathological study of six cases with an emphasis on differential diagnosis from metastatic cancer. J Clin Pathol; 2003 Oct;56(10):742-6
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  • [Title] Osteosarcoma with cytokeratin expression: a clinicopathological study of six cases with an emphasis on differential diagnosis from metastatic cancer.
  • Tumours were located on the long bones of the extremities in five patients and the ilium in one.
  • Preoperative and postoperative chemotherapy was given to five of the six patients, but the effects of these agents were negligible.
  • Three of the six patients developed lung metastases, whereas the other three patients have remained well with no evidence of local recurrence or distant metastasis.
  • The clinicopathological features were similar to those of patients with conventional osteosarcoma, except for a higher age, chemotherapy resistance, histological epithelioid features, and pleomorphism.
  • [MeSH-major] Biomarkers, Tumor / analysis. Bone Neoplasms / chemistry. Bone Neoplasms / secondary. Keratins / analysis. Osteosarcoma / chemistry. Osteosarcoma / secondary
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Epithelioid Cells / pathology. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 14514776.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 68238-35-7 / Keratins
  • [Other-IDs] NLM/ PMC1770076
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4. Bertoni F, Bacchini P, Staals EL, Davidovitz P: Dedifferentiated parosteal osteosarcoma: the experience of the Rizzoli Institute. Cancer; 2005 Jun 1;103(11):2373-82
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  • BACKGROUND: Dedifferentiated parosteal osteosarcoma (DPOS) is a variant of osteosarcoma in which a high-grade sarcoma coexists with a conventional parosteal osteosarcoma (c-POS), either at presentation (synchronous type) or at the time of recurrence (metachronous type).
  • The authors reviewed the clinical and radiologic features, histologic sections, treatments, and outcomes in this group of patients with DPOS.
  • One tumor involved the scapula, one involved the ilium, and another involved the skull.
  • Twenty-eight patients underwent surgery, and 18 of those patients received chemotherapy (5 patients received neoadjuvant chemotherapy, and 13 patients received adjuvant).
  • Of the nine patients who died, one patient received no treatment, five patients underwent surgery (with three patients achieving adequate margins) in combination with chemotherapy, and three patients underwent surgery only (with adequate margins achieved).
  • Of the 20 patients who remained alive, 13 patients underwent surgery (with 10 patients achieving adequate margins) in combination with chemotherapy, whereas 7 patients underwent surgery only (all with adequate margins).
  • One patient died of causes unrelated to the tumor, and another patient died shortly after undergoing resection of a lesion in the skull.
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Agents / therapeutic use. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Prognosis. Retrospective Studies. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15852358.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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5. Yagisawa K, Aiba A, Momoi A, Tsukada N, Nikkuni K, Aoki S, Aizawa Y: High-dose cyclophosphamide as an effective therapy for a patient with refractory multiple myeloma relapsing after autologous stem cell transplantation. Intern Med; 2005 May;44(5):471-5
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  • [Title] High-dose cyclophosphamide as an effective therapy for a patient with refractory multiple myeloma relapsing after autologous stem cell transplantation.
  • However, it is not common for high-dose cyclophosphamide (CPM) therapy to be used as a treatment for MM.
  • After this treatment, the serum calcium level decreased and the tumor mass in the iliac bone was reduced.
  • This therapy is potentially useful for patients with refractory MM.
  • [MeSH-major] Antineoplastic Agents, Alkylating / administration & dosage. Cyclophosphamide / administration & dosage. Multiple Myeloma / therapy. Neoplasm Recurrence, Local / drug therapy. Peripheral Blood Stem Cell Transplantation / adverse effects
  • [MeSH-minor] Bone Marrow / pathology. Dose-Response Relationship, Drug. Female. Follow-Up Studies. Humans. Ilium / radiography. Middle Aged. Skull / radiography. Tomography, X-Ray Computed. Transplantation, Autologous

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  • (PMID = 15942097.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 8N3DW7272P / Cyclophosphamide
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6. Ohata N, Ozaki T, Kunisada T, Morimoto Y, Tanaka M, Inoue H: Extended total sacrectomy and reconstruction for sacral tumor. Spine (Phila Pa 1976); 2004 Mar 15;29(6):E123-6
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  • [Title] Extended total sacrectomy and reconstruction for sacral tumor.
  • STUDY DESIGN: This case report includes the results of long-term follow-up after extended total sacrectomy in a 13-year-old boy with a sarcoma originating in the sacrum with an extraskeletal extension and infiltration into the left ilium.
  • OBJECTIVE: To report and discuss a case of sacral tumor treated by extended sacrectomy.
  • SUMMARY OF BACKGROUND DATA: Sacral tumors are often at an advanced stage with a large volume at diagnosis.
  • Although total or extended sacrectomy is the only radical means to treat the massive sacral tumor, unavoidable complications in total sacrectomy are serious in the treatment selection.
  • Additional genetic analysis redesignated the tumor as an unclassified sarcoma.
  • Preoperative neoadjuvant chemotherapy and radiotherapy were completed.
  • The response to the preoperative treatment appeared as a reduction in tumor size (approximately 50%) on radiographs.
  • CONCLUSIONS: The patient's excellent response to preoperative antitumor treatment was considered crucial to the long-term outcome.
  • But the decision between a radical resection with reconstruction and a less extensive procedure with combined therapy remains controversial.
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Cisplatin. Combined Modality Therapy. Dacarbazine / administration & dosage. Diagnostic Errors. Doxorubicin / administration & dosage. Fibula / transplantation. Follow-Up Studies. Humans. Ifosfamide / administration & dosage. Ilium / pathology. Ilium / surgery. Internal Fixators. Intervertebral Disc Displacement / diagnosis. Laminectomy. Lumbar Vertebrae / surgery. Male. Mesna / administration & dosage. Neoadjuvant Therapy. Neoplasm Invasiveness. Radiotherapy, Adjuvant. Recovery of Function. Rhizotomy. Spinal Nerve Roots / pathology. Spinal Nerve Roots / surgery

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  • (PMID = 15014287.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; NR7O1405Q9 / Mesna; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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7. Guo W, Li D, Tang X, Yang Y, Ji T: Reconstruction with modular hemipelvic prostheses for periacetabular tumor. Clin Orthop Relat Res; 2007 Aug;461:180-8
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  • [Title] Reconstruction with modular hemipelvic prostheses for periacetabular tumor.
  • We designed a modular hemipelvic prosthetic system to reconstruct the pelvis and evaluated the early clinical outcome of the prosthesis using 3-year survival rate, local recurrence rate, Musculoskeletal Tumor Society (MSTS) 93 function score, and complications.
  • We retrospectively reviewed 28 patients who had pelvic tumor resections and reconstructions using the new hemipelvic prostheses between 2001 and 2005.
  • Sixteen (57.1%) patients had Types II and III (periacetabular and pubis) pelvic resections, seven had Types I and II (periacetabular and ilium) pelvic resections, and five had Type II (periacetabular) pelvic resection.
  • Six patients with osteosarcoma had chemotherapy.
  • None received radiation therapy.
  • [MeSH-minor] Acetabulum. Adolescent. Adult. Female. Hip Prosthesis. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Prosthesis Design. Reconstructive Surgical Procedures. Recovery of Function. Retrospective Studies

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  • (PMID = 17452921.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Collini P, Mezzelani A, Modena P, Dagrada P, Tamborini E, Luksch R, Gronchi A, Navarria P, Sozzi G, Pilotti S: Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone. Am J Surg Pathol; 2003 Aug;27(8):1161-6
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  • [Title] Evidence of neural differentiation in a case of post-therapy primitive neuroectodermal tumor/Ewing sarcoma of bone.
  • Neural differentiation with the appearance of ganglion-like cells has been reported in untreated primitive neuroectodermal tumor/Ewing sarcoma (PNET/EWS) at peculiar sites, such as the cauda equina, and following treatment.
  • The case is presented here of a 17-year-old girl with a tumor in the iliac bone.
  • The tumor had the typical morphology of this tumor type and showed diffuse membranous immunoreactivity for CD99, intense immunoreactivity for synaptophysin, and focal immunoreactivity for neuron-specific enolase and S-100 protein.
  • The patient underwent chemotherapy and radiotherapy, followed by right internal hemipelvectomy.
  • The post-treatment residual viable tumor showed a morphologic appearance resembling a neuroblastoma, with immunoreactivity for NB84a, Hu, synaptophysin, and chromogranins A and B, but not for CD99.
  • RT-PCR performed on tumor tissue before and after therapy showed the presence of the EWS-FLI1 fusion transcript, type I in both samples.
  • This case of PNET/EWS is unique in the sense of showing the typical fusion transcript associated with this tumor both in the morphologically typical pretherapy tumor and in the sample from the post-therapy specimen showing neuroblastoma-like features.
  • [MeSH-minor] Adolescent. Biomarkers, Tumor. Cell Transformation, Neoplastic. Disease-Free Survival. Female. Humans. Ilium / pathology. Ilium / radiography. Neoplasms, Second Primary. Neuroblastoma / genetics. Neuroblastoma / pathology. Neuroblastoma / therapy. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. Proto-Oncogene Protein c-fli-1. RNA, Messenger / metabolism. RNA, Neoplasm / analysis. RNA-Binding Protein EWS. Reverse Transcriptase Polymerase Chain Reaction. Transcription Factors / genetics. Transcription Factors / metabolism

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  • (PMID = 12883251.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / EWS-FLI fusion protein; 0 / Oncogene Proteins, Fusion; 0 / Proto-Oncogene Protein c-fli-1; 0 / RNA, Messenger; 0 / RNA, Neoplasm; 0 / RNA-Binding Protein EWS; 0 / Transcription Factors
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9. Saada E, Thariat J, Follana P, Birtwisle-Peyrottes I, Haudebourg J, Trojani C, Bacque P, Thyss A: Primitive neuroectodermal tumor of the pelvis in an elderly patient. Onkologie; 2009 Sep;32(8-9):499-502
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  • [Title] Primitive neuroectodermal tumor of the pelvis in an elderly patient.
  • Outcome was favorable after combined modality treatment including chemotherapy based on the Memphis protocol - adapted from that used for Ewing's sarcoma in children - and surgery.
  • CONCLUSION: Our case is uncommon because of the age at diagnosis, the fortuitous way of revelation, and the choice of dose-intense chemotherapy adapted from the Memphis protocol (cyclophosphamide- and doxorubicin-based) for children, which was efficient and safe.
  • It supports the fact that an adult, and even an old patient, with good physical status, may be treated safely and radically even with dose-adapted aggressive chemotherapy.
  • [MeSH-major] Bone Neoplasms / pathology. Ilium / pathology. Neuroectodermal Tumors, Primitive / pathology. Pelvic Neoplasms / pathology

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  • (PMID = 19745594.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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10. Mattioli S, D'Ovidio F, Tazzari P, Pilotti V, Daddi N, Bandini G, Piccioli M, Pileri S: Iliac crest biopsy versus rib segment resection for the detection of bone marrow isolated tumor cells from lung and esophageal cancer. Eur J Cardiothorac Surg; 2001 May;19(5):576-9
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  • [Title] Iliac crest biopsy versus rib segment resection for the detection of bone marrow isolated tumor cells from lung and esophageal cancer.
  • OBJECTIVE: The presence of isolated tumor cells in the bone marrow affects the prognosis of both esophageal cancer and non-small cell lung cancer (NSCLC).
  • Therefore, preoperative assessment of isolated tumor cells may be useful to plan multimodality treatment.
  • Rib segment resection at surgery provides adequate amounts of bone marrow for the detection of isolated tumor cells while bone marrow aspirate from the iliac crest does not.
  • The iliac crest biopsy according to the Jamshidi technique procures a core of tissue apt for histology and not simply for cytology.
  • The aim of this study was to compare the accuracy of iliac crest biopsy versus rib segment resection in the diagnosis of isolated tumor cells in order to obtain a useful preoperative approach.
  • None had chemotherapy prior to evaluation.
  • Positive cytokeratin neoplastic cells were searched by immunohistochemistry on tissue sections from the iliac crest biopsies and by flow cytometry on cell suspensions from the rib segments.
  • RESULTS: Isolated tumor cells were detected in the rib segments of ten patients.
  • CONCLUSION: Our results suggest that, if the diagnosis of bone marrow isolated tumor cells has clinical relevance, the preoperative assessment should be performed by rib segment resection or methods other than iliac crest aspirate or biopsy.
  • Further investigation is needed to determine whether isolated tumor cells have a preferential spread to chest bones other than distant bone sites.
  • [MeSH-major] Adenocarcinoma / pathology. Bone Marrow Neoplasms / secondary. Carcinoma, Squamous Cell / pathology. Esophageal Neoplasms / pathology. Ilium / pathology. Lung Neoplasms / pathology. Ribs / pathology
  • [MeSH-minor] Biopsy. Cardia. Humans. Immunohistochemistry. Neoplasm Staging / methods. Stomach Neoplasms / pathology


11. Guo W, Tang XD, Li X, Ji T, Sun X: [The analysis of the treatment of giant cell tumor of the pelvis and sacrum]. Zhonghua Wai Ke Za Zhi; 2008 Apr 1;46(7):501-5
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  • [Title] [The analysis of the treatment of giant cell tumor of the pelvis and sacrum].
  • OBJECTIVE: To discuss the surgical management, local recurrence rate and complications of giant cell tumor (GCTs) of the pelvic and sacrum.
  • According to the site of the tumors on the bone, they was classified into three regions: 8 patients involved region I (ilium), 10 region II (acetabulum) and 4 region III (ischiopubic).
  • Surgical management: 2 patients received 3 times of operations and 7 underwent 2 operations.
  • There were 19 patients managed with intralesional marginal excision and 2 patients with intralesional marginal excision and adjuvant radiotherapy, another 3 patients with widely marginal excision as the treatment of sacral lesions.
  • Nineteen patients underwent the enbloc excision except 2 involved ischium and 1 involved ilium for the managements of pelvic lesions.
  • RESULTS: One recurrent patient with the large, ragged tumor died of serious infection in 2 weeks after the second surgery.
  • One patient of malignant giant cell tumor of sacrum died at 15 months after surgery.
  • One patient with sacral lesion occurred pulmonary metastases in two years after surgery, and received chemotherapy with ADM, DDP and IFO.
  • One year later there was no much change in metastatic tumor.
  • CONCLUSIONS: The treatment for GCT of the pelvic and sacrum should be more aggressive because of high incidence of local recurrence after intralesional excision.
  • Although it might induce sacral nerve deficit, widely marginal excision is the best surgical procedure because of its low recurrence rate.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Pelvic Bones. Sacrum

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  • (PMID = 18785558.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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12. Mochizuki K, Katayama K, Kikuchi F, Saito I, Homori M: Immunoglobulin D myeloma presenting as an extraosseous soft tissue tumor. Skeletal Radiol; 2001 Mar;30(3):166-9
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  • [Title] Immunoglobulin D myeloma presenting as an extraosseous soft tissue tumor.
  • We report a 69-year-old man who suffered an extraosseous tumor of immunoglobulin D myeloma (lambda type) in the shoulder girdle, mimicking a primary soft tissue sarcoma.
  • The tumor was isointense with adjacent muscle on T1-weighted MR images, and hyperintense on T2-weighted images.
  • After administration of gadolinium, the central part of the tumor showed marked contrast enhancement.
  • Although the tumor showed a complete response to the initial chemotherapy, the patient died of the disease 31 months after its initial manifestation.
  • Several bone marrow aspirations and biopsies of the ilium and sternum had shown no increase in plasma cells (range 0.6-1.2%) until the disease became advanced 19 months after its initial manifestation.
  • [MeSH-major] Multiple Myeloma / diagnosis. Shoulder. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Dacarbazine / therapeutic use. Doxorubicin / therapeutic use. Humans. Ifosfamide / therapeutic use. Immunoglobulin D. Immunoglobulin lambda-Chains. Magnetic Resonance Imaging. Male. Mesna / therapeutic use

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  • (PMID = 11357456.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Immunoglobulin D; 0 / Immunoglobulin lambda-Chains; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; NR7O1405Q9 / Mesna; UM20QQM95Y / Ifosfamide; MAID protocol
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13. Ebelin M, Missenard G, Nordin JY: [Iatrogenic tumor metastasis to the pelvis after treatment for hand osteosarcoma. A case report]. Chir Main; 2000 Nov;19(5):272-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Iatrogenic tumor metastasis to the pelvis after treatment for hand osteosarcoma. A case report].
  • This was first treated by curettage, iliac bone graft and internal fixation, without any complementary investigation being carried out, i.e., no preliminary biopsy and histological diagnosis were made.
  • Moreover, the definitive diagnosis was only made four months later, when biopsy findings confirmed the presence of an osteosarcoma.
  • After neoadjuvant chemotherapy, an en-bloc resection of the second metatarsal and the trapezoid bone was carried out.
  • However, nearly a year later the discovery of a large tumor mass at the site where the iliac bone graft was originally taken necessitated resection of the hemi-pelvis, with chemotherapy prior to resection and radiotherapy following surgery.
  • Unfortunately, this salvage procedure did not limit the spread of the disease, and subsequent pulmonary and vertebral metastases were found, leading to the death of the patient three years after the initial fracture.
  • [MeSH-major] Bone Neoplasms / pathology. Bone Transplantation / adverse effects. Curettage / adverse effects. Fracture Fixation, Internal / adverse effects. Fractures, Spontaneous / etiology. Hand Injuries / etiology. Iatrogenic Disease. Ilium / transplantation. Metacarpus / injuries. Neoplasm Seeding. Osteosarcoma / secondary. Pelvic Bones
  • [MeSH-minor] Biopsy. Combined Modality Therapy. Fatal Outcome. Hemipelvectomy. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Prognosis. Salvage Therapy. Tomography, X-Ray Computed


14. Chiras J, Adem C, Vallée JN, Spelle L, Cormier E, Rose M: Selective intra-arterial chemoembolization of pelvic and spine bone metastases. Eur Radiol; 2004 Oct;14(10):1774-80
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  • The purpose of this study was to determine the effect of interventional palliative therapy by using chemoembolization on metastatic bone pain and tumor bulk in inoperable metastases where chemotherapy and radiotherapy had failed.
  • Therapeutic agents were carboplatin for selective chemotherapy and pirarubicin mixed with polyvinyl alcohol foam for chemoembolization.
  • Fifteen of 18 (83%) patients had significant pain relief, as shown by the decrease of analgesic drug use.
  • Selective intra-arterial chemoembolization gives longer pain relief than embolization, compared to the literature data, probably because of partial response with local anti-cancer drugs.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Bone Neoplasms / secondary. Chemoembolization, Therapeutic / methods. Doxorubicin / analogs & derivatives. Pelvic Bones / pathology. Spinal Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Antibiotics, Antineoplastic / administration & dosage. Antineoplastic Agents / administration & dosage. Carboplatin / administration & dosage. Female. Follow-Up Studies. Humans. Ilium / pathology. Infusions, Intra-Arterial. Lumbar Vertebrae / pathology. Male. Middle Aged. Pain Measurement. Palliative Care. Polyvinyl Alcohol / administration & dosage. Sacrum / pathology. Thoracic Vertebrae / pathology

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  • [Copyright] Copyright 2004 Springer-Verlag
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  • (PMID = 15034742.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents; 80168379AG / Doxorubicin; 9002-89-5 / Polyvinyl Alcohol; BG3F62OND5 / Carboplatin; D58G680W0G / pirarubicin
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15. Donati D, Yin J, Di Bella C, Colangeli M, Bacci G, Ferrari S, Bertoni F, Barbieri E, Mercuri M: Local and distant control in non-metastatic pelvic Ewing's sarcoma patients. J Surg Oncol; 2007 Jul 1;96(1):19-25
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  • The purpose of this study was to review our experience and evaluate the role of different local treatment in non-metastatic pelvic ES patients.
  • Among the 73 eligible patients, 17 (23%) with progression of tumor growth during induction chemotherapy eventually died.
  • The analysis was focused on the remaining 56 patients with good or stable clinical response to the chemotherapy.
  • RESULTS: Patients treated with surgery, with or without radiation therapy, had a better local control (82.6% vs. 66.7%) and a significantly higher rate of 5-year EFS (73.9% vs. 30.3%, P = 0.036) than those who were only treated with local radiation therapy.
  • CONCLUSION: Chemotherapy is the key factor in the treatment of pelvic ES.
  • In our series, surgical treatment was associated with good prognosis for pelvic ES.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / surgery. Pelvic Bones. Sarcoma, Ewing / drug therapy. Sarcoma, Ewing / surgery
  • [MeSH-minor] Adolescent. Adult. Child. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Dactinomycin / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Female. Humans. Ilium. Male. Middle Aged. Survival Analysis. Vincristine / administration & dosage

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  • [Copyright] Copyright 2007 Wiley-Liss, Inc.
  • (PMID = 17345611.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide
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16. Sagar TG, Chandra A, Raman SG, Swaminathan R: Paucity of hematological neoplasia after treatment of Hodgkin disease: observation after long-term follow-up at Cancer Institute, Chennai, south India. Pediatr Hematol Oncol; 2002 Apr-May;19(3):197-203
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  • [Title] Paucity of hematological neoplasia after treatment of Hodgkin disease: observation after long-term follow-up at Cancer Institute, Chennai, south India.
  • The purpose of the study was to evaluate the incidence of second malignancies in childhood Hodgkin disease treated with COPP and COPP/ABV (replacing mechlorethamine by cyclophosphamide) chemotherapy.
  • All 5 were solid tumors: one each of soft tissue sarcoma, dermatofibrosarcoma, micropapillary carcinoma of thyroid, malignant phylloides tumor of breast, and chondrosarcoma of ilium.
  • All patients had received combination chemotherapy and radiotherapy.
  • All these patients had advanced stage of cancer and were 7-14 years of age at the time of diagnosis of first primary Hodgkin disease.
  • COPP and COPP/ABV are effective therapeutic regimens.
  • The paucity of secondary hematological malignancies is unique in this series and may be attributed to the substitution of nitrogen mustard with cyclophosphamide in the chemotherapy combination.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Hematologic Neoplasms / chemically induced. Hodgkin Disease / drug therapy
  • [MeSH-minor] Bleomycin / administration & dosage. Child, Preschool. Cyclophosphamide / administration & dosage. Disease-Free Survival. Doxorubicin / administration & dosage. Female. Humans. Incidence. Infant. Infant, Newborn. Male. Neoplasms, Second Primary / chemically induced. Neoplasms, Second Primary / prevention & control. Prednisone / administration & dosage. Procarbazine / administration & dosage. Survival Rate. Treatment Outcome. Vinblastine / administration & dosage. Vincristine / administration & dosage

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  • (PMID = 11936733.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 35S93Y190K / Procarbazine; 5J49Q6B70F / Vincristine; 5V9KLZ54CY / Vinblastine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CVPPABO protocol
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17. Handa H, Irisawa H, Komatsumoto S, Matsushima T, Tsukamoto N, Nojima Y, Murakami H: [Plasmacytoma with multiple hypervascular lesions revealed by angiography in a patient with multiple myeloma]. Rinsho Ketsueki; 2006 Jun;47(6):521-5
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  • A 68-year-old woman suffering from a left iliac tumor and severe back pain was admitted to another hospital in May 1999.
  • The bone X-ray, CT scan and MRI demonstrated a 7 cm x 5 cm left iliac tumor with osteolysis and she was transferred to our hospital.
  • Angiography demonstrated multiple hypervascular lesions in the left ilium, lumbar vertebrae, left ischium, left pubis and left rib.
  • The tumor was resected and diagnosed as a plasmacytoma.
  • Her symptoms improved following 3 courses of MCNU-VMP therapy and the bone marrow plasma cells decreased to less than 5%.
  • She was discharged and treated as an outpatient but relapsed and died of chemotherapy-resistant myeloma.
  • [MeSH-minor] Aged. Angiography. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone and Bones / blood supply. Bone and Bones / radiography. Drug Administration Schedule. Female. Humans. Melphalan / administration & dosage. Nitrosourea Compounds / administration & dosage. Prednisolone / administration & dosage. Prednisone / administration & dosage. Tomography, X-Ray Computed. Vindesine / administration & dosage

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  • (PMID = 16862980.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Nitrosourea Compounds; 9PHQ9Y1OLM / Prednisolone; Q41OR9510P / Melphalan; RSA8KO39WH / Vindesine; VB0R961HZT / Prednisone; AP protocol 2; MCNU-VMP protocol
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18. Abdulkader I, Cameselle-Teijeiro J, Fraga M, Caparrini A, Forteza J: Sclerosing epithelioid fibrosarcoma primary of the bone. Int J Surg Pathol; 2002 Jul;10(3):227-30
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  • Sclerosing epithelioid fibrosarcoma (SEF) is an uncommon tumor originally described in soft tissues.
  • The tumor was grossly well circumscribed.
  • The histologic examination disclosed a hypocellular neoplasm with densely hyalinized stroma.
  • To our knowledge, this is the first tumor of this kind described in the bone.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Drug Therapy. Female. Humans. Ilium. Immunohistochemistry. Sclerosis / pathology. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 12232581.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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19. Ruiz Tovar J, Reguero Callejas ME, Arano Bermejo JI, Capote Armas LF, González-Palacios Martínez F, Cabañas Navarro L: Malignant mixed Mullerian tumors. Clin Transl Oncol; 2006 Feb;8(2):129-32
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  • Treatment in 2 patients was hysterectomy with double ooforectomy, and resection of the pelvic mass was the treatment in the third case.
  • Adjuvant radio chemotherapy was administrated in 2 of the 3 cases.
  • [MeSH-major] Mixed Tumor, Mullerian / pathology. Uterine Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bone Neoplasms / secondary. Breast Neoplasms / secondary. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Fatal Outcome. Female. Femoral Neoplasms / secondary. Humans. Hysterectomy. Ifosfamide / administration & dosage. Ilium. Middle Aged. Neoplasms, Second Primary. Ovariectomy. Paclitaxel / administration & dosage. Palliative Care. Pelvic Neoplasms / secondary. Pelvic Neoplasms / surgery. Prognosis. Radiotherapy, Adjuvant. Sarcoma, Ewing. Spinal Neoplasms / secondary

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  • [Cites] Chirurgie. 1996;121(3):198-202 [8945826.001]
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  • (PMID = 16632428.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 8N3DW7272P / Cyclophosphamide; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide
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20. Cho HS, Oh JH, Han I, Kim HS: Joint-preserving limb salvage surgery under navigation guidance. J Surg Oncol; 2009 Sep 1;100(3):227-32
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  • We performed navigation-assisted limb salvage surgeries on patients with a malignant bone tumor of the metaphysis of the long bone or the iliac bone while preserving the adjacent joint.
  • METHODS: When preoperative chemotherapy was estimated to be effective by imaging studies and the residual remaining epiphysis was expected to be more than 1 cm long after tumor resection with 1-2 cm of surgical margin, joint-preserving surgery was performed under navigation guidance.
  • [MeSH-major] Bone Neoplasms / surgery. Femoral Neoplasms / surgery. Ilium / surgery. Limb Salvage / methods. Magnetic Resonance Imaging, Interventional. Radiography, Interventional. Surgery, Computer-Assisted

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  • (PMID = 19330812.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Boyle MJ, Hornicek FJ, Robinson DS, Mnaymneh W: Internal hemipelvectomy for solitary pelvic thyroid cancer metastases. J Surg Oncol; 2000 Sep;75(1):3-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND OBJECTIVES: Radioactive iodine (RAI) therapy remains a primary treatment modality for metastatic thyroid carcinoma, but poor tumor uptake of the agent can limit its usefulness.
  • While offering effective palliation, radiation therapy is not curative, and chemotherapy is even less useful.
  • METHODS: We describe 3 cases of thyroid cancer metastatic to the pelvic girdle that were unresponsive to RAI and other nonoperative therapies, which presented over a 15-year time period.
  • One patient, found postoperatively to have a positive surgical margin, developed a local recurrence at 4 months and died.
  • A second patient developed a local recurrence at 11 months and died.
  • She is alive, disease-free, and ambulatory with the aid of a cane 32 months after the original procedure.
  • CONCLUSIONS: We propose this surgical procedure in selected patients with metastatic pelvic thyroid cancer.
  • [MeSH-minor] Acetabulum. Adult. Aged. Female. Humans. Ilium. Male. Middle Aged. Reconstructive Surgical Procedures. Thyroidectomy

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  • [Copyright] Copyright 2000 Wiley-Liss, Inc.
  • (PMID = 11025455.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] UNITED STATES
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22. Pesl M, Safarík L, Dusková J, Soukup V, Dundr P, Donociková B, Dvorácek J: [A case of a patient with solitary prostate metastasis of the colorectal carcinoma three years after abdominoperineal amputation of the rectum]. Rozhl Chir; 2004 Jul;83(7):333-6
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  • [Transliterated title] Prípad pacienta se solitární metastázou kolorektálního karcinomu v prostatĕ tri roky po abdominoperineální amputaci rekta.
  • RESULTS: The study describes a case of a 42-year-old patient who underwent abdominoperineal amputation for the rectal carcinoma pT3 N1 M0 with complementary actinotherapy and chemotherapy.
  • Elevation of the CEA was found upon laboratory examination, other tumor markers including the PSA were not abnormal.
  • The positron emission tomography (PET) did not disclose other distant foci.
  • The patient was administered 4 courses of chemotherapy with, basically, no signs of regression in the prostate foci.
  • Our team decided on salvage cystoprostatectomy, securing urine derivation by the ilium conduit.
  • 6 months later, the CT examination showed a massive local relapse and two metastatic foci in the liver, further oncological therapy was not indicated.
  • CONCLUSION: This case-review points out a possibility of metastatic prostate affections connected to the colorectal carcinoma disorder, as well as its treatment procedures.

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  • (PMID = 15373203.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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23. Yokoyama R, Beppu Y, Tobisu Ki K, Moriya Y, Uchiyama K, Kito M, Umeda T, Hasegawa T, Shimoda T: A multidisciplinary approach to the treatment of malignant pelvic bone tumors: results with eight consecutive patients. J Orthop Sci; 2000;5(5):449-56
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  • [Title] A multidisciplinary approach to the treatment of malignant pelvic bone tumors: results with eight consecutive patients.
  • The prognosis for malignant pelvic bone tumors is worse than that for malignant bone tumors of the extremities because definitive surgery in the pelvis is often difficult to accomplish.
  • The histologic diagnosis was osteosarcoma in five patients, chondrosarcoma in two, and Ewing's sarcoma in one.
  • Five lesions arose in the ilium and three in the pubis.
  • The extraosseous tumors decreased in size and/or were encapsulated as a result of preoperative chemotherapy in six patients, four of these achieving a wide surgical margin.
  • With respect to tumor location and surgical margin, all five lesions in the ilium involved the sacrum, four of these being resected with an inadequate margin.
  • Our results indicate that a patient's chances of definitive surgery may be enhanced by a multidisciplinary approach, although the management of sacroiliac involvement remains challenging.
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Chondrosarcoma / surgery. Female. Humans. Male. Middle Aged. Postoperative Complications. Reconstructive Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 11180901.001).
  • [ISSN] 0949-2658
  • [Journal-full-title] Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
  • [ISO-abbreviation] J Orthop Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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24. Oya N, Kokubo M, Mizowaki T, Shibamoto Y, Nagata Y, Sasai K, Nishimura Y, Tsuboyama T, Toguchida J, Nakamura T, Hiraoka M: Definitive intraoperative very high-dose radiotherapy for localized osteosarcoma in the extremities. Int J Radiat Oncol Biol Phys; 2001 Sep 1;51(1):87-93
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Definitive intraoperative very high-dose radiotherapy for localized osteosarcoma in the extremities.
  • PURPOSE: To evaluate the outcome and adverse effects in patients with osteosarcoma treated with very high-dose definitive intraoperative radiotherapy (IORT), with the intention of saving the affected limb.
  • METHODS AND MATERIALS: Thirty-nine patients with osteosarcoma in their extremities were treated with definitive IORT.
  • The irradiation field included the tumor plus an adequate wide margin and excluded the major vessels and nerves.
  • Forty-five to 80 Gy of electrons or X-rays were delivered.
  • Distant metastasis developed in 23 patients; 19 died and 4 were alive for >10 years.
  • CONCLUSIONS: Very high-dose definitive IORT combined with preventive nailing and chemotherapy appeared to be a promising quality-of-life-oriented alternative to treating patients with osteosarcomas in the extremities, although the problem of recurrences from the surrounding unirradiated soft tissue remains to be solved.
  • [MeSH-minor] Adolescent. Adult. Child. Combined Modality Therapy. Female. Femoral Neoplasms / mortality. Femoral Neoplasms / pathology. Femoral Neoplasms / radiotherapy. Humans. Humerus. Ilium. Intraoperative Period. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy Dosage. Tibia. Treatment Outcome

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  • (PMID = 11516856.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Oshikawa G, Arai A, Sasaki K, Ichinohasama R, Miura O: [Primary multifocal osseous Hodgkin lymphoma]. Rinsho Ketsueki; 2009 Feb;50(2):92-6
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  • Despite normal findings on X-ray and CT scan at a previous hospital, sternal tumor had arisen and fever, night sweat, and weight loss developed 5 months before admission.
  • Core needle biopsy of the sternal tumor was performed and a diagnosis of Hodgkin lymphoma (HL) (mixed cellularity) was made.
  • FDG-PET scan demonstrated increased FDG uptake in the sternum, the right ilium, the right 9(th) rib, and the lower edge of the left scapula, but there were no other apparent lesions.
  • After 6 cycles of ABVD, the patient achieved complete remission and local radiotherapy for the right ilium was added.
  • Since there have not yet been any characteristic symptoms or laboratory findings identified, the diagnosis of osseous HL is difficult and may be delayed.
  • Although systemic chemotherapy appears to have been effective in the reported cases, more cases should be reviewed to clarify its pathophysiological features.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hodgkin Disease / diagnosis. Neoplasms, Multiple Primary
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / administration & dosage. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Humans. Positron-Emission Tomography. Remission Induction. Tomography, X-Ray Computed. Vinblastine / administration & dosage

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  • (PMID = 19265301.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5V9KLZ54CY / Vinblastine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; ABVD protocol
  • [Number-of-references] 15
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26. Jeanrot C, Ouaknine M, Anract P, Carlioz A, Forest M, Tomeno B: [Primary leiomyosarcoma of bone. Report of 5 anatomo-clinical cases and review of the literature]. Rev Chir Orthop Reparatrice Appar Mot; 2000 Feb;86(1):63-73
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  • INTRODUCTION: Leiomyosarcoma is a malignant smooth muscle tumor occurring most frequently in uterus or soft tissues and more rarely in bone.
  • RESULTS: The tumors were located respectively in the distal tibia (n=2), the distal femur, the sternum and the ilium (n=1).
  • This tumor arises more commonly in adults (mean age: 49 years) with an equal gender distribution and involves predominantly the long bones near the knee.
  • The diagnosis is based on microscopic features demonstrating fusiform tumor cells arranged in interwoven bundles, and the immunohistochemical results of widespread cytoplasmic positivity for smooth muscle actin.
  • Surgery constitutes the main treatment since chemotherapy or radiotherapy did not provide an improved prognosis over a wide resection.
  • [MeSH-major] Bone Neoplasms / diagnosis. Leiomyosarcoma / diagnosis

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  • (PMID = 10669826.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] FRANCE
  • [Number-of-references] 53
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27. Fang Z, Yi X, Li M, Zhu T: Anterior approach to the second thoracic vertebral body for surgical treatment (vertebrectomy, bone grafting, and titanium alloy plate fixation). Int J Clin Oncol; 2001 Aug;6(4):205-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Anterior approach to the second thoracic vertebral body for surgical treatment (vertebrectomy, bone grafting, and titanium alloy plate fixation).
  • X-ray, computed tomography (CT), and magnetic resonance imaging (MRI) examinations indicated breakdown of the second thoracic vertebral body and arch, associated with spinal cord compression.
  • After one course of chemotherapy with cyclophosphamide and prednisone (CP protocol), surgery was carried out.
  • Without wedging the sternum, we separated tissue from the posterior of the sternum to the second and third thoracic vertebrae, excised the second thoracic vertebra to expose the hard spinal meninges, and removed the tumor in the vertebral canal to release the compression on the spinal cord.
  • An autogeneous bone graft, taken from the right ilium (1.5 x 1.5 x 3 cm in size), was implanted between the first and third thoracic vertebrae, and a spinal titanium alloy plate was used to increase fixation between the first and third thoracic vertebrae from the front.
  • [MeSH-minor] Adult. Alloys. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / administration & dosage. Female. Humans. Magnetic Resonance Imaging. Paraplegia / etiology. Paraplegia / therapy. Prednisone / administration & dosage. Spinal Cord Compression / etiology. Titanium. Tomography, X-Ray Computed

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  • (PMID = 11706559.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Alloys; 8N3DW7272P / Cyclophosphamide; D1JT611TNE / Titanium; VB0R961HZT / Prednisone
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28. Hong A, Stevens G, Stalley P, Pendlebury S, Ahern V, Ralston A, Estoesta E, Barrett I: Extracorporeal irradiation for malignant bone tumors. Int J Radiat Oncol Biol Phys; 2001 Jun 1;50(2):441-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The treated sites were femur (7), tibia (4), humerus (2), ilium (2), and sacrum (1).
  • Following induction chemotherapy in Ewing's sarcomas and osteosarcoma, en bloc resection of the tumor and tumor-bearing bone was performed.
  • A single dose of 50 Gy was delivered to the bone extracorporeally using either a linear accelerator (9 cases) or a blood product irradiator (7 cases).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Male. Neoadjuvant Therapy. Treatment Outcome

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  • (PMID = 11380232.001).
  • [ISSN] 0360-3016
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Trial; Journal Article; Multicenter Study
  • [Publication-country] United States
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29. Jackson RJ, Gokaslan ZL: Spinal-pelvic fixation in patients with lumbosacral neoplasms. J Neurosurg; 2000 Jan;92(1 Suppl):61-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The authors have used a modification of the Galveston technique, originally described by Allen and Ferguson in the treatment of scoliosis, to achieve rigid spinal-pelvic fixation in patients with lumbosacral neoplasms.
  • Previous treatment included spinal surgery in 10 (77%), radiation therapy in seven (54%), and/or chemotherapy in six (46%).
  • Following tumor resection, fixation was achieved by intraoperative placement of contoured titanium rods bilaterally into the ilium.
  • Two patients experienced neurological dysfunction (ankle weakness and neurogenic bladder) that was thought to be related to tumor resection rather than the fixation procedure.
  • Spinal pain, as measured by a visual analog pain scale and determined by medication consumption was significantly reduced in 85% (11 cases).

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  • (PMID = 10616060.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
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