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Items 1 to 25 of about 25
1. Tan DS, Eng PC, Lim ST, Tao M: Primary tracheal lymphoma causing respiratory failure. J Thorac Oncol; 2008 Aug;3(8):929-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary tracheal lymphoma causing respiratory failure.
  • We describe a 24-year-old woman with tracheal non-Hodgkin lymphoma who was initially diagnosed with asthma, but subsequently presented with near-fatal acute upper airway obstruction because of a tracheal Anaplastic Lymphoma Kinase (ALK)+ anaplastic T-cell lymphoma.
  • After six cycles of Cyclophosphamide, Doxorubicin, Vincristine, Prednisolone chemotherapy, the patient went into complete clinical remission.
  • A high index of suspicion in patients with dyspnoea and wheeze unresponsive to bronchodilators is crucial in early diagnosis of tracheal tumors.
  • [MeSH-major] Lymphoma, T-Cell / complications. Respiratory Insufficiency / etiology. Tracheal Neoplasms / complications
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / metabolism. Combined Modality Therapy. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Female. Humans. Prednisone / therapeutic use. Protein-Tyrosine Kinases / metabolism. Receptor Protein-Tyrosine Kinases. Remission Induction. Tomography, X-Ray Computed. Vincristine / therapeutic use

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  • [ErratumIn] J Thorac Oncol. 2008 Oct;3(10):1193. Thye, Lim Soon [corrected to Lim, Soon Thye]
  • (PMID = 18670314.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; EC 2.7.10.1 / Protein-Tyrosine Kinases; EC 2.7.10.1 / Receptor Protein-Tyrosine Kinases; EC 2.7.10.1 / anaplastic lymphoma kinase; VB0R961HZT / Prednisone; CHOP protocol
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2. Kang JY, Park HJ, Lee KY, Lee SY, Kim SJ, Park SH, Kim YK: Extranodal marginal zone lymphoma occurring along the trachea and central airway. Yonsei Med J; 2008 Oct 31;49(5):860-3
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  • [Title] Extranodal marginal zone lymphoma occurring along the trachea and central airway.
  • Extranodal marginal zone lymphoma is a low-grade B cell lymphoma that presents with an indolent clinicopathologic nature.
  • Although this tumor can occur in various sites, including the gastrointestinal tract and lungs, it develops and spreads extremely rarely along the trachea and central airway.
  • We report a case of extranodal lymphoma of mucosa-associated lymphoid tissue with tracheobronchial involvement.
  • Bronchoscopic evaluation confirmed diffuse, multiple nodular lesions in both the trachea and large bronchi, and she was diagnosed with an extranodal marginal zone lymphoma of the tracheobronchial tree.
  • After systemic chemotherapy, she survived for more than 18 months.
  • [MeSH-major] Bronchial Diseases / pathology. Lymphoma, B-Cell, Marginal Zone / pathology. Tracheal Diseases / pathology

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  • [Cites] Thorax. 2004 Dec;59(12):1100 [15563713.001]
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  • (PMID = 18972610.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2615368
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3. Ambrosini V, Quarta C, Zinzani PL, Fini M, Giavaresi G, Torricelli P, Malvi D, Nanni C, Grassetto G, Rubello D, Fanti S: 18F-FDG small animal PET for early detection of human anaplastic large cells lymphoma xenograft in immunocompromised mice. Anticancer Res; 2008 Mar-Apr;28(2A):981-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 18F-FDG small animal PET for early detection of human anaplastic large cells lymphoma xenograft in immunocompromised mice.
  • The purpose of the present study was to assess if small animal PET is useful for serially monitoring the development of a human anaplastic large cell lymphoma (ALCL) murine xenograft and for the early selection of tumour bearing animals.
  • Small animal 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) was serially performed (intravenous injected dose: 20 MBq in < 0.15 ml, uptake time: 60 min, image acquisition: 1 bed position of 15 min): early PET at 2 days after cell inoculation in 4/8 mice and at 4 days in the remainig 4/8, later PET scans were performed in all the animals at 7, 14, 21 and 28 days after inoculation.
  • Of the two remaining mice, one died after the first PET scan (thus preventing any evaluation of detection time) while the other showed a microscopic neoplastic infiltration at tracheal level at autopsy.
  • [MeSH-major] Lymphoma, Large-Cell, Anaplastic / diagnosis. Positron-Emission Tomography / veterinary

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  • (PMID = 18507045.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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4. Hosoya Y, Yokoyama T, Arai W, Hyodo M, Nishino H, Sugawara Y, Yasuda Y, Nagai H: Tracheoesophageal fistula secondary to chemotherapy for malignant B-cell lymphoma of the thyroid: successful surgical treatment with jejunal interposition and mesenteric patch. Dis Esophagus; 2004;17(3):266-9
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  • [Title] Tracheoesophageal fistula secondary to chemotherapy for malignant B-cell lymphoma of the thyroid: successful surgical treatment with jejunal interposition and mesenteric patch.
  • We report a case of tracheoesophageal fistula (TEF) secondary to chemotherapy for primary thyroid lymphoma.
  • A 65-year-old man with a short history of a rapidly enlarging neck mass was diagnosed as having thyroid lymphoma of diffuse, large B-cell type.
  • The TEF occurred during the first course of chemotherapy including cyclophosphamide, doxorubicin, vincristine and prednisolone.
  • After placing a feeding gastrostomy without oral intake, eight cycles of chemotherapy were completed and complete remission was achieved.
  • This seems to be the first report of a TEF caused by chemotherapy for primary thyroid B-cell lymphoma.
  • A variety of treatments for TEF including simple closure, tracheal resection, colonic bypass and muscle flap have been reported with low success rates.
  • Our procedure using a jejunal mesenteric patch seems to be unique and may be a new treatment strategy for TEF.

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  • (PMID = 15361103.001).
  • [ISSN] 1120-8694
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone
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5. Louie BE, Harlock J, Hosein A, Miller JD: Laser therapy for an obstructing primary tracheal lymphoma in a patient with AIDS. Can Respir J; 2005 Mar;12(2):86-8
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  • [Title] Laser therapy for an obstructing primary tracheal lymphoma in a patient with AIDS.
  • A patient with AIDS presented with progressive dyspnea leading to respiratory failure with near complete airway obstruction due to primary tracheal lymphoma.
  • Laser therapy was used locally to debulk the tumour, which facilitated extubation and led to definitive treatment with chemotherapy.
  • [MeSH-major] Airway Obstruction / therapy. Laser Therapy. Lymphoma, AIDS-Related / therapy. Tracheal Neoplasms / therapy
  • [MeSH-minor] Adult. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 15785798.001).
  • [ISSN] 1198-2241
  • [Journal-full-title] Canadian respiratory journal
  • [ISO-abbreviation] Can. Respir. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
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6. Gasparetto TD, Azevedo FB, Toledo A, Zanetti G, Marchiori E: Primary tracheal non-Hodgkin lymphoma: case report with an emphasis on computed tomography findings. J Thorac Imaging; 2010 May;25(2):W24-6
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  • [Title] Primary tracheal non-Hodgkin lymphoma: case report with an emphasis on computed tomography findings.
  • The computed tomography scan demonstrated irregular, lobulated narrowing of the trachea, and parenchymal consolidations containing air bronchogram, peribronchial thickening, and cavitations.
  • Afterward, the patient was referred for a bronchoscopy with a biopsy of the tracheal mucosa.
  • The samples were submitted to immunohistochemical analysis and revealed a diagnosis of diffuse large B-cell non-Hodgkin lymphoma of the trachea.
  • Antibiotic treatment was proposed as a first treatment.
  • The patient did not receive intensive chemotherapy because of his comorbid conditions and died 2 months later.
  • [MeSH-major] Lymphoma, Non-Hodgkin / radiography. Tomography, X-Ray Computed / methods. Tracheal Neoplasms / radiography

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  • (PMID = 20351583.001).
  • [ISSN] 1536-0237
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Takami A, Okumura H, Maeda Y, Kumano Y, Asakura H, Oda M, Omura K, Nakao S: Primary tracheal lymphoma: case report and literature review. Int J Hematol; 2005 Nov;82(4):338-42
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  • [Title] Primary tracheal lymphoma: case report and literature review.
  • We describe a 20-year-old Japanese woman with anaplastic large cell lymphoma in whom primary tracheal involvement was associated with life-threatening airway obstruction.
  • After debulking surgery, the patient was successfully treated with chemotherapy and radiotherapy.
  • A total of 28 cases of primary tracheal lymphoma were reviewed.
  • Common clinical features included predominance of localized disease, respiratory symptoms resembling acute asthma, absence of hemoptysis, and rapid progression of tracheal stenosis.
  • Various histological subtypes of primary tracheal lymphoma exist and are likely to determine prognosis.
  • [MeSH-major] Lymphoma / diagnosis. Tracheal Neoplasms / diagnosis

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  • (PMID = 16298827.001).
  • [ISSN] 0925-5710
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Japan
  • [Number-of-references] 30
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8. Suzuki T, Akizawa T, Suzuki H, Kitazume K, Omine M, Mitsuya T: Primary tracheal mucosa-associated lymphoid tissue lymphoma accompanying lung cancer. Common tumorigenesis or coincidental coexistence? Jpn J Thorac Cardiovasc Surg; 2000 Dec;48(12):817-9
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  • [Title] Primary tracheal mucosa-associated lymphoid tissue lymphoma accompanying lung cancer. Common tumorigenesis or coincidental coexistence?
  • We report a 67-year-old patient with coexistent tracheal non-Hodgkin's lymphoma and lung cancer the first case, to our knowledge, of this concomitant incidence in the literature.
  • Biopsy of the unanticipated tracheal irregularity revealed non-Hodgkin's lymphoma, compatible with mucosa-associated lymphoid tissue lymphoma.
  • After right upper lobectomy, chemotherapy for non-Hodgkin's lymphoma was conducted, but the patient died 11 months postoperatively of pulmonary fibrosis.
  • Pulmonary fibrosis was suspected of having progressed from drug-induced pneumonitis caused by anticancer drugs.
  • A common tumorigenetic factor may thus exist between tracheobronchial mucosa-associated lymphoid tissue lymphoma and lung cancer.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Lung Neoplasms / pathology. Lymphoma, B-Cell, Marginal Zone / pathology. Lymphoma, Non-Hodgkin / pathology. Neoplasms, Multiple Primary. Tracheal Neoplasms / pathology

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  • (PMID = 11197829.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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9. Gill MT, Cotelingam JD, Lowery-Nordberg M, Nathan CO: Tracheal non-Hodgkin's lymphoma masquerading as benign granulation tissue: a report of two cases. Ann Otol Rhinol Laryngol; 2010 Jul;119(7):431-5
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  • [Title] Tracheal non-Hodgkin's lymphoma masquerading as benign granulation tissue: a report of two cases.
  • Primary tracheal non-Hodgkin's lymphoma (NHL) is rare, with fewer than 30 cases reported to date.
  • We review the clinical presentation, evaluation, and treatment of 2 cases of tracheal NHL mimicking granulation tissue.
  • The first patient was a 67-year-old man with myelodysplastic syndrome and Crohn's disease who had a recurring lesion of the proximal trachea causing significant airway obstruction.
  • The second patient was a 47-year-old man with a history of multiple intubations who presented with dyspnea and stridor due to circumferential tracheal stenosis.
  • In both cases, bronchoscopy revealed abundant granulation tissue, and the initial biopsy results indicated benign disease.
  • However, after requests from the diagnostic team to rule out lymphoma, additional immunohistochemical stains and polymerase chain reaction testing confirmed NHL.
  • The second patient died of airway obstruction due to severe distal tracheal stenosis.
  • Recurrent granulation tissue should raise the suspicion of malignancy and prompt further tissue evaluation for evidence of lymphoma.
  • Steroids for airway compromise may cause progression to mature stenosis as prednisone is used in the treatment of lymphoma.
  • Localized disease involving the central airways may be treated successfully with limited chemotherapy and radiotherapy.
  • [MeSH-major] Granulation Tissue / pathology. Lymphoma, Non-Hodgkin / diagnosis. Tracheal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Bronchoscopy. Fatal Outcome. Humans. Male. Middle Aged. Tomography, X-Ray Computed. Tracheal Stenosis / diagnostic imaging. Tracheal Stenosis / pathology

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  • (PMID = 20734962.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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10. Huang IA, Hsia SH, Wu CT, Jaing TH, Lai SH, Liu YH: Combined chemotherapy and tracheobronchial stenting for life-threatening airway obstruction in a child with endobronchial non-Hodgkin lymphoma. Pediatr Hematol Oncol; 2004 Dec;21(8):725-9
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  • [Title] Combined chemotherapy and tracheobronchial stenting for life-threatening airway obstruction in a child with endobronchial non-Hodgkin lymphoma.
  • Endobronchial involvement in non-Hodgkin lymphoma is rare even in the presence of advanced disease.
  • An airway stenting was used in this patient because he had severe tracheal obstruction from the tumor.
  • The compromised airway was alleviated by combined chemotherapy and tracheobronchial stenting.
  • [MeSH-major] Airway Obstruction / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bronchial Neoplasms / therapy. Lymphoma, Non-Hodgkin / therapy. Stents
  • [MeSH-minor] Adolescent. Bronchi / surgery. Bronchoscopy. Critical Illness. Humans. Male. Pulmonary Atelectasis / etiology. Pulmonary Atelectasis / therapy. Trachea / surgery

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  • (PMID = 15739628.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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11. Damas C, Fernandes G, Magalhães A, Hespanhol VP: [Unusual diagnosis of tracheal obstruction]. Rev Port Pneumol; 2006 May-Jun;12(3):303-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Unusual diagnosis of tracheal obstruction].
  • This exam showed multiple lesions in the trachea, nearly 2 cm above the vocal cords that compromised the airway and did not allow the progression of the bronchoscope.
  • For this reason, it was decided to introduce a tracheal prosthesis.
  • The histological specimen was compatible with anaplastic Lymphoma, CD 30+.
  • The trachea was permeable after this.
  • He is clinically stable and under monitoring, having now completed a chemotherapy treatment with CHOP (Ciclophosphamide, Adriamycin or Hydroxydorubicin, Vincristine or Oncovin and Prednisone).
  • The primary mediastinal Large Cells Lymphoma represents 11.5% of the Large Cells Lymphomas (2% of the non-Hodgkin's Lymphomas).
  • This neoplasm is in many studies considered incurable, but there are some positive results with the combination of radiotherapy and chemotherapy.
  • If there is any airway compromise, the tracheal prosthesis may be one option for the resolution of the respiratory insufficiency.
  • [MeSH-major] Lymphoma, Large-Cell, Anaplastic / diagnosis. Tracheal Neoplasms / diagnosis

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  • (PMID = 16967180.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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12. Fujita M, Miura H, Yasuda D, Hasegawa D, Orima H: Tracheal narrowing secondary to airway obstruction in two cats. J Small Anim Pract; 2004 Jan;45(1):29-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tracheal narrowing secondary to airway obstruction in two cats.
  • Tracheal narrowing is described in two cats.
  • In both cases, inspiratory radiographs demonstrated tracheal narrowing just cranial to the thoracic inlet; no narrowing was seen on expiratory radiographs.
  • Magnetic resonance imaging revealed suspected nasal tumours in both cases, but no abnormalities were identified in the region of the narrowed trachea.
  • Nasal biopsy confirmed intranasal lymphoma in one cat and nasal adenocarcinoma in the other.
  • The former cat was treated with chemotherapy.
  • The owner of the latter cat declined further treatment.
  • The tracheal narrowing disappeared after the initiation of chemotherapy in the cat with intranasal lymphoma and it is suggested that the narrowing might have been associated with the nasal tumour.
  • A careful evaluation of the airway, especially cranial to the narrowing, is recommended in cases of tracheal narrowing in cats.
  • [MeSH-major] Adenocarcinoma / veterinary. Cat Diseases / diagnosis. Lymphoma / veterinary. Nasal Obstruction / veterinary. Nose Neoplasms / veterinary
  • [MeSH-minor] Animals. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cats. Diagnosis, Differential. Male

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  • (PMID = 14756207.001).
  • [ISSN] 0022-4510
  • [Journal-full-title] The Journal of small animal practice
  • [ISO-abbreviation] J Small Anim Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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13. Cobzeanu MD, Costinescu V, Rusu CD, Mihailovici S, Grigoras M, Miron L, Paduraru D, Arama A: Laryngotracheal non-Hodgkin's lymphoma. Chirurgia (Bucur); 2010 Jan-Feb;105(1):131-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngotracheal non-Hodgkin's lymphoma.
  • OBJECTIVES: Malignant lymphomas of larynx and trachea are rare tumors and require special diagnostic and therapeutic attention.
  • The authors present an unexpected case of nonHodgkin Lymphoma localized in the subglottic larynx and upper cervical trachea.
  • The clinical presentation, diagnostic and therapeutic approach, evolution and prognosis are discussed.
  • The flexible endoscopy and CT-scan revealed a large mass arising from the subglottic larynx and anterior wall of upper cervical trachea with the obstruction of 2/3 of the laryngotracheal lumen.
  • The histopathologic exam of the surgical specimen showed malignant nonHodgkin lymphoma and the immunohistochemical profiles were evaluated in order to establish the therapeutic strategy including chemotherapy in the Department of Oncology.
  • CONCLUSIONS: Invasion of the subglottic larynx and trachea by lymphoma is an uncommon problem which can cause severe airway obstruction and requires multidisciplinary approach (ENT, pneumology, oncology/hematology).
  • [MeSH-major] Laryngeal Neoplasms / pathology. Lymphoma, B-Cell / pathology. Tracheal Neoplasms / pathology
  • [MeSH-minor] Adult. Airway Obstruction / etiology. Chemotherapy, Adjuvant. Diagnosis, Differential. Humans. Male. Radiotherapy, Adjuvant. Tracheotomy. Treatment Outcome

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  • (PMID = 20405695.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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14. Hashemzadeh S, Tubbs RS, Fakhree MB, Shoja MM: Mucormycotic pseudoaneurysm of the common carotid artery with tracheal involvement. Mycoses; 2008 Jul;51(4):347-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucormycotic pseudoaneurysm of the common carotid artery with tracheal involvement.
  • We describe a patient with acute lymphoblastic leukaemia (L2 subtype) who developed a neck mass following a course of induction chemotherapy.
  • The patient then developed haemoptysis.
  • Surgical exploration revealed a necrotic right common carotid artery with anteromedial pseudoaneurysm and adjacent tracheal wall perforation.
  • Local debridement and tracheal repair were performed.
  • Although rare, clinicians should be aware of these possible presenting features of mucormycosis as early diagnosis and treatment may potentially improve the survival.
  • [MeSH-major] Aneurysm, False / microbiology. Carotid Artery, Common / microbiology. Mucormycosis / complications. Mucormycosis / diagnosis. Precursor Cell Lymphoblastic Leukemia-Lymphoma / complications
  • [MeSH-minor] Adult. Amphotericin B / therapeutic use. Antifungal Agents / therapeutic use. Humans. Male. Mucorales / cytology. Tracheal Diseases / etiology. Tracheal Diseases / surgery

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  • (PMID = 18855846.001).
  • [ISSN] 1439-0507
  • [Journal-full-title] Mycoses
  • [ISO-abbreviation] Mycoses
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antifungal Agents; 7XU7A7DROE / Amphotericin B
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15. Uenogawa K, Hatta Y, Oshiro S, Hagikura K, Takahashi N, Kura Y, Yamazaki T, Akashiba T, Sawada U, Horie T: [Bronchoesophageal fistula in a patient with untreated malignant lymphoma]. Rinsho Ketsueki; 2005 Sep;46(9):1071-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Bronchoesophageal fistula in a patient with untreated malignant lymphoma].
  • We report here an unusual case of lymphoma with a therapy-unrelated bronchoesophageal fistula.
  • A 70-year-old male was diagnosed as having gastric diffuse large B-cell lymphoma in May 1998.
  • When tracheal intubation was performed with bronchoscopy, a bronchoesophageal fistula was revealed.
  • Malignant lymphoma cells were found around the fistula in the biopsy specimen.
  • The patient died of pneumonia after treatment with airway stenting and chemotherapy.
  • Induction of necrosis by chemotherapy or low blood flow with stenting and dopamine probably caused enlargement of the fistula.
  • [MeSH-major] Bronchial Fistula / etiology. Esophageal Fistula / etiology. Lymphoma, B-Cell / complications. Lymphoma, Large B-Cell, Diffuse / complications
  • [MeSH-minor] Aged. Fatal Outcome. Humans. Male. Pneumonia, Aspiration / etiology. Pneumonia, Aspiration / therapy. Stents / adverse effects

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  • (PMID = 16440767.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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16. Valenti V, Martínez-Cecilia D, Priego P, Cohen P, Martínez-Isla A: Bronchoesophageal fistula in a patient with non-Hodgkin's lymphoma. Clin Transl Oncol; 2008 Jun;10(6):377-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bronchoesophageal fistula in a patient with non-Hodgkin's lymphoma.
  • Bronchoesophageal fistula secondary to lymphoma is a very rare condition, usually associated with chemo-radiotherapy.
  • We report a case of a patient with a non-Hodgkin's lymphoma (NHL) who, after chemotherapy, developed an oesophago-tracheal fistula.
  • Right thoracotomy oesophagectomy and closure of the tracheal defect with an intercostal muscle flap and pericardial patch was performed.
  • Unlike oesophageal cancer, NHL can have a good prognosis, so curative treatment of the fistula can be considered.
  • Conservative treatment must always be the first option, leaving stenting or surgery for when the problem persists.
  • [MeSH-major] Bronchial Fistula / etiology. Bronchial Fistula / surgery. Lymphoma, Non-Hodgkin / complications. Tracheoesophageal Fistula / etiology. Tracheoesophageal Fistula / surgery
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Humans. Male

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  • (PMID = 18558587.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
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17. Kalinyak JE, Kong CS, McDougall IR: Burkitt's lymphoma presenting as a rapidly growing thyroid mass. Thyroid; 2006 Oct;16(10):1053-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Burkitt's lymphoma presenting as a rapidly growing thyroid mass.
  • A 53-year-old man was admitted to the hospital because of tracheal compressive symptoms from a rapidly expanding thyroid mass.
  • A fine-needle aspiration (FNA) biopsy showed a monotonous population of intermediate-sized lymphoid cells with scant cytoplasm suspicious for lymphoma.
  • Twelve hours later an emergent computed tomography (CT) scan confirmed left tracheal deviation with compression, however, there were no signs of tumor invasion.
  • The patient received emergent CHOP (clophosphamide, adriamycin, vincristine, prednisone) and rituxan therapy.
  • Bone marrow biopsy provided the final diagnosis of stage IV Burkitt's lymphoma and his therapy was changed to hyper CVAD-R chemotherapy (cytoxan, vincristine, adriamycin, dexamethasone, rituxan).
  • To our knowledge, this is only the second reported case of Burkitt's lymphoma presenting as a thyroid mass.
  • His presentation highlights the urgency in diagnosis and provides an opportunity to review a rare type of primary thyroid lymphoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Burkitt Lymphoma / diagnosis. Burkitt Lymphoma / drug therapy. Thyroid Diseases / diagnosis

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  • (PMID = 17042693.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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18. Maeda T, Yamada Y, Tawara M, Yamasaki R, Yakata Y, Tsutsumi C, Onimaru Y, Kamihira S, Tomonaga M: Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody. Int J Hematol; 2001 Jul;74(1):70-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful treatment with a chimeric anti-CD20 monoclonal antibody (IDEC-C2B8, rituximab) for a patient with relapsed mantle cell lymphoma who developed a human anti-chimeric antibody.
  • Mantle cell lymphoma (MCL) has a poor prognosis without cure; the median overall survival ranges only from 3 to 4 years irrespective of conventional therapeutic regimens.
  • We report a patient with relapsed MCL who was successfully treated with IDEC-C2B8 for over a year although she developed HACA 6 months after the initial administration of IDEC-C2B8 in the phase II clinical trial conducted by Zenyaku Kogyo Co. Ltd.
  • The present findings suggested that IDEC-C2B8 is effective and safe even in patients who have developed HACA.
  • [MeSH-major] Antibodies, Anti-Idiotypic / biosynthesis. Antibodies, Monoclonal / therapeutic use. Immunotherapy. Lymphoma, Mantle-Cell / therapy
  • [MeSH-minor] Aged. Antibodies, Monoclonal, Murine-Derived. Antigens, CD20 / immunology. Antigens, Neoplasm / immunology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Resistance, Multiple. Drug Resistance, Neoplasm. Enzyme-Linked Immunosorbent Assay. Female. Humans. Lymphocyte Count. Neoplasm Recurrence, Local. Rituximab. Tracheal Neoplasms / radiotherapy

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  • (PMID = 11530808.001).
  • [ISSN] 0925-5710
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Anti-Idiotypic; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antigens, CD20; 0 / Antigens, Neoplasm; 4F4X42SYQ6 / Rituximab
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19. Hon KL, Leung A, Chik KW, Chu CW, Cheung KL, Fok TF: Critical airway obstruction, superior vena cava syndrome, and spontaneous cardiac arrest in a child with acute leukemia. Pediatr Emerg Care; 2005 Dec;21(12):844-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report the unusual presentation of a previously healthy girl with sudden cardiopulmonary arrest caused by acute lymphoblastic leukemia and mediastinal involvement leading to acute tracheal and airway obstruction.
  • Despite active resuscitation and mechanical ventilation, she developed severe cerebral edema as a result of cerebral asphyxia.
  • Because of severe asphyxia leading to brain death and renal failure, chemotherapy was withheld.
  • Her white cell count spontaneously reverted to reference range without chemotherapy.
  • [MeSH-major] Airway Obstruction / etiology. Heart Arrest / etiology. Leukemia-Lymphoma, Adult T-Cell / diagnosis. Superior Vena Cava Syndrome / etiology


20. Kishi Y, Negishi M, Kami M, Hamaki T, Miyakoshi S, Ueyama J, Morinaga S, Mutou Y: Fatal airway obstruction caused by invasive aspergillosis of the thyroid gland. Leuk Lymphoma; 2002 Mar;43(3):669-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We experienced a patient who developed thyrotoxicosis and fatal airway obstruction caused by invasive aspergillosis of the thyroid.
  • A 26-year-old man was admitted to our hospital for the treatment of non-Hodgkin's lymphoma.
  • During myelosuppression following the chemotherapy, he developed cervical swelling and hyperthyroidism.
  • We suspected lymphoma infiltration to the thyroid, and irradiated it with a total of 26 Gy.
  • Necrotic tissues of the thyroid protruded into the tracheal lumen, causing airway obstruction.

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  • (PMID = 12002779.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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21. Brown MR, Rogers KS, Mansell KJ, Barton C: Primary intratracheal lymphosarcoma in four cats. J Am Anim Hosp Assoc; 2003 Sep-Oct;39(5):468-72

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary intratracheal lymphosarcoma in four cats.
  • Cats treated with systemic chemotherapy or radiation were able to achieve complete remission and long-term resolution of clinical signs.
  • [MeSH-major] Cat Diseases / diagnosis. Lymphoma, Non-Hodgkin / veterinary. Tracheal Neoplasms / veterinary
  • [MeSH-minor] Animals. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bronchoscopy / veterinary. Cats. Combined Modality Therapy. Cough / etiology. Cough / veterinary. Cyanosis / etiology. Cyanosis / veterinary. Diagnosis, Differential. Dyspnea / etiology. Dyspnea / veterinary. Female. Male. Respiratory Sounds / etiology. Respiratory Sounds / veterinary

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  • (PMID = 14518655.001).
  • [ISSN] 0587-2871
  • [Journal-full-title] Journal of the American Animal Hospital Association
  • [ISO-abbreviation] J Am Anim Hosp Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Choudhary C, Gildea TR, Salman R, Guzman ED, Mehta AC: Management of tracheomediastinal fistula using self-expanding metallic stents. Ann Thorac Surg; 2008 May;85(5):1800-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The mass was diagnosed as a large cell lymphoma, and the decision was made to undertake chemotherapy only after stabilization of the endobronchial tree.
  • The endobronchial defects were successfully palliated with placement of three different types of self-expanding metallic stents using a flexible bronchoscope under conscious sedation.
  • [MeSH-major] Bronchial Fistula / therapy. Bronchial Neoplasms / complications. Fistula / therapy. Lymphoma, Large B-Cell, Diffuse / complications. Lymphoma, Non-Hodgkin / complications. Mediastinal Diseases / therapy. Mediastinal Neoplasms / complications. Stents. Tracheal Diseases / therapy

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  • (PMID = 18442595.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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23. Shimizu K: [Oncogenic emergency and treatment in thyroid disease]. Nihon Geka Gakkai Zasshi; 2004 Apr;105(4):266-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Oncogenic emergency and treatment in thyroid disease].
  • The urgent treatment of thyroid disease is mainly considered to be that of thyroid neoplasia, especially malignant thyroid tumors.
  • The clinical symptoms produced by malignant neoplasia are acute respiratory failure caused by tumor compression and/or invasion of the trachea.
  • Massive bleeding caused by tumor invasion of the major vessels also requires emergency therapy.
  • However, anaplastic carcinoma, undifferentiated papillary carcinoma, and malignant lymphoma originating from the thyroid sometimes require urgent therapy to save lives.
  • Anaplastic carcinoma that is basically transformed from well-differentiated papillary carcinoma shows rapid growth and invades the surrounding tissue to produce tracheal obstruction.
  • Urgent treatment of these diseases consists of ensuring that the airway remains open to improve quality of life, but does not include radical treatment.
  • Stent insertion is one adequate method for the urgent treatment of respiratory disturbance caused by tumor compression.
  • Malignant lymphoma frequently develops from Hashimoto's thyroiditis.
  • Immediately after making an accurate pathologic diagnosis, chemotherapy and/or radiation therapy are effective in reducing enlarged goiters rather than surgical management.
  • [MeSH-minor] Emergencies. Hemorrhage / therapy. Humans. Respiratory Insufficiency / therapy

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  • (PMID = 15112486.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 6
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24. Alifano M, Parri SN, Arab WA, Bonfanti B, Lacava N, Porrello C, Boaron M: Limited upper sternotomy in general thoracic surgery. Surg Today; 2008;38(4):300-4
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  • The remaining indications were as follows: to assess residual disease following chemotherapy for Hodgkin's disease in 7 patients and for non-Hodgkin lymphoma in 1; for tracheal surgery in 7; and for excision of nodal mediastinal metastasis of non-thyroid cancer in 2.
  • There was no surgical mortality but complications developed in eight patients.
  • CONCLUSION: The upper sternal split provides a satisfactory access to perform a surgical procedure in the superior mediastinum in most diseases.
  • The procedure is safe and involves minimal surgical trauma.
  • [MeSH-minor] Female. Humans. Male. Middle Aged. Myasthenia Gravis / surgery. Retrospective Studies. Thymoma / surgery. Thymus Neoplasms / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18368317.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
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25. Ricketts RR: Clinical management of anterior mediastinal tumors in children. Semin Pediatr Surg; 2001 Aug;10(3):161-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of the many clinical, functional, and radiologic criteria used to identify the children at greatest risk for anesthetic complications, the peak expiratory flow rate (PEFR) and the tracheal cross-section area seem to be the most reliable.
  • General anesthesia should not be administered to children if the PEFR and a tracheal cross section area are both less than 50% of predicted values.
  • [MeSH-major] Germinoma / therapy. Mediastinal Neoplasms / therapy
  • [MeSH-minor] Adolescent. Burkitt Lymphoma / diagnosis. Child. Child, Preschool. Drug Therapy. Female. Hodgkin Disease / therapy. Humans. Lymphoma, Non-Hodgkin / therapy. Male. Neoplasm Staging. Risk Assessment

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  • [Copyright] Copyright 2001 by W.B. Saunders Company
  • (PMID = 11481654.001).
  • [ISSN] 1055-8586
  • [Journal-full-title] Seminars in pediatric surgery
  • [ISO-abbreviation] Semin. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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