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1. Zielińska E, Bodalski J: Growth retardation and osteomalacia as a result of ifosfamide nephrotoxicity in a 3-year-old boy whose genotype reveals the genes encoding glutathione S-transferases GSTM1 and GSTT1. Cytobios; 2001;106(413):193-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A case of a child with growth retardation and prolonged osteomalacia, as a result of chronic renal tubulopathy, following successful therapy for a sacral-coccygeal germinal tumour, is described.
  • Intense chemotherapy resulted in an increased risk of chronic side effects.
  • [MeSH-major] Antineoplastic Agents, Alkylating / adverse effects. Glutathione Transferase / deficiency. Growth Disorders / etiology. Ifosfamide / adverse effects. Kidney / drug effects. Kidney Diseases / complications. Osteomalacia / etiology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child, Preschool. Genetic Predisposition to Disease / genetics. Humans. Male. Sacrococcygeal Region / pathology. Teratoma / drug therapy. Teratoma / pathology. Treatment Outcome. Water-Electrolyte Balance / drug effects. Water-Electrolyte Balance / physiology

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  • (PMID = 11523744.001).
  • [ISSN] 0011-4529
  • [Journal-full-title] Cytobios
  • [ISO-abbreviation] Cytobios
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; EC 2.5.1.- / glutathione S-transferase T1; EC 2.5.1.18 / Glutathione Transferase; EC 2.5.1.18 / glutathione S-transferase M1; UM20QQM95Y / Ifosfamide
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2. Shonubi AM, Musa AA, Akiode O, Salami BA, Kingu HJ, Adnan SM: Mature sacrococcygeal teratoma: a case report and literature review. West Afr J Med; 2004 Apr-Jun;23(2):176-9
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  • [Title] Mature sacrococcygeal teratoma: a case report and literature review.
  • BACKGROUND: Sacrococcygeal teratomas are derived from embryonic germ cell layers.
  • Modern imaging technique may be helpful to delineate the extent of the mass but surgical excision is generally indicated at the time of detection.
  • RESULTS: A three day old female baby presented with a mature sacrococcygeal teratoma containing well-developed limb buds.
  • CONCLUSION: Sacrococcygeal teratoma is a rare tumour that may be benign or malignant.
  • Complete excision is the primary therapy and is adequate if the tumour is benign.
  • Chemotherapy and radiotherapy are however indicated in malignant cases and in recurrence after previous excision.
  • [MeSH-major] Sacrococcygeal Region. Teratoma
  • [MeSH-minor] Biopsy. Female. Humans. Infant, Newborn. Nigeria. Postoperative Care / methods. Rare Diseases / blood. Rare Diseases / congenital. Rare Diseases / diagnosis. Rare Diseases / surgery. Skin Care / methods. Surgical Flaps. Tomography, X-Ray Computed. Treatment Outcome. Wound Healing. alpha-Fetoproteins / metabolism

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  • (PMID = 15287301.001).
  • [ISSN] 0189-160X
  • [Journal-full-title] West African journal of medicine
  • [ISO-abbreviation] West Afr J Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Nigeria
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
  • [Number-of-references] 24
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3. Göbel U, Calaminus G, Schneider DT, Koch S, Teske C, Harms D: The malignant potential of teratomas in infancy and childhood: the MAKEI experiences in non-testicular teratoma and implications for a new protocol. Klin Padiatr; 2006 Nov-Dec;218(6):309-14
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  • [Title] The malignant potential of teratomas in infancy and childhood: the MAKEI experiences in non-testicular teratoma and implications for a new protocol.
  • Patients with immaturity grade 2 and 3 according to Gonzales-Crussi were eligible for adjuvant chemotherapy.
  • 4) In MAKEI 83/86/89 four newborns with teratoma died due to perioperative complications and nine children as a result of tumor progression, whereas in MAKEI 96 no newborn died, only one child died from tumor progression, and another child died during long time observation for another reason (meningitis).
  • 5) In accordance to the experience of the MAKEI 83/86/89 studies, no child of the MAKEI 96 study presented with yolk sac tumor at recurrence if adjuvant chemotherapy was administered during first-line treatment because of immaturity.
  • In contrast, more than half of the children with tumor recurrence after watch and wait strategy had yolk sac tumor in addition to teratoma.
  • [MeSH-major] Ovarian Neoplasms. Teratoma
  • [MeSH-minor] Adolescent. Adult. Age Factors. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Chi-Square Distribution. Child. Child, Preschool. Data Interpretation, Statistical. Disease Progression. Female. Humans. Infant. Infant, Newborn. Male. Neoplasm Recurrence, Local. Neoplasm Staging. Neoplasms, Germ Cell and Embryonal / pathology. Ovary / pathology. Prospective Studies. Randomized Controlled Trials as Topic. Sacrococcygeal Region. Sex Factors. Treatment Outcome. World Health Organization

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  • (PMID = 17080332.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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4. Göbel U, Schneider DT, Calaminus G, Jürgens H, Spaar HJ, Sternschulte W, Waag K, Harms D: Multimodal treatment of malignant sacrococcygeal germ cell tumors: a prospective analysis of 66 patients of the German cooperative protocols MAKEI 83/86 and 89. J Clin Oncol; 2001 Apr 01;19(7):1943-50
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  • [Title] Multimodal treatment of malignant sacrococcygeal germ cell tumors: a prospective analysis of 66 patients of the German cooperative protocols MAKEI 83/86 and 89.
  • PURPOSE: To evaluate a multimodal approach including surgery and cisplatinum chemotherapy for treatment of children with malignant sacrococcygeal germ cell tumors (GCT) and to compare adjuvant and neoadjuvant strategies in advanced tumors.
  • PATIENTS AND METHODS: Between 1983 and 1995, 71 patients with malignant sacrococcygeal GCT were prospectively enrolled onto the German protocols for nontesticular GCT Maligne Keimzelltumoren 83/86 and 89.
  • Five patients who received no chemotherapy (n = 2) or nonplatinum chemotherapy (n = 2) or who did not undergo tumor resection (n = 1) were excluded from this analysis.
  • RESULTS: Fifty-two patients presented with locally advanced stage T2 tumors, and 30 patients had distant metastases at diagnosis.
  • Patients received a median of eight cycles (range, four to nine cycles) of cisplatinum-based chemotherapy.
  • Thirty-five patients underwent tumor resection at diagnosis and received adjuvant cisplatinum-based chemotherapy (group A).
  • Thirty-one patients received up-front chemotherapy followed by delayed tumor resection (group B).
  • Preoperative chemotherapy facilitated complete tumor resections (group B, 20 of 31 patients; group A, five of 35 patients, P <.001) and avoided second-look surgery.
  • Metastases at diagnosis and completeness of the first attempt of tumor resection were significant prognostic predictors; however, metastases were not predictive for patients treated with up-front chemotherapy.
  • Four patients died as a result of therapy-related complications, and eight patients died of their tumors.
  • Patients with locally advanced and metastatic tumors (T2b M1) fared better with neoadjuvant treatment [overall survival: 0.83 +/- 0.09 (16 of 19 patients) versus 0.45 +/- 0.15 (five of 11 patients), P =.01].
  • CONCLUSION: Even locally advanced and metastatic sacrococcygeal GCT can be successfully treated with up-front cisplatinum-based chemotherapy followed by delayed but complete tumor resection.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Neoplasms, Germ Cell and Embryonal / therapy
  • [MeSH-minor] Actuarial Analysis. Child. Child, Preschool. Cisplatin / administration & dosage. Cisplatin / adverse effects. Combined Modality Therapy. Female. Germany / epidemiology. Germinoma / drug therapy. Germinoma / mortality. Germinoma / surgery. Humans. Infant. Male. Prognosis. Regression Analysis. Risk. Sacrococcygeal Region. Statistics, Nonparametric. Teratoma / drug therapy. Teratoma / mortality. Teratoma / surgery

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  • (PMID = 11283126.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin
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5. Biskup W, Calaminus G, Schneider DT, Leuschner I, Göbel U: Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96. Klin Padiatr; 2006 Nov-Dec;218(6):303-8
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  • [Title] Teratoma with malignant transformation: experiences of the cooperative GPOH protocols MAKEI 83/86/89/96.
  • BACKGROUND: The designation of a teratoma with malignant transformation (TMT) refers to the occurrence of somatic non-germ cell malignancies within a teratoma.
  • PATIENTS AND METHODS: Between 1982 and 2003, 641 patients with extracranial nontesticular pure teratoma (256 coccygeal, 246 ovarian, 139 other sites) were reported to the MAKEI protocols 83/86/89/96 by various, mainly German centres.
  • Patients with teratoma and somatic malignancy were identified by database queries.
  • Resection was performed in seven patients (including both coccygeal tumors) and adjuvant chemotherapy was administered in one of them.
  • Two patients relapsed after resection, but both were cured with chemotherapy.
  • Two patients suffered from advanced tumors and both were treated with primary chemotherapy.
  • CONCLUSIONS: Malignant transformation of pure teratomas constitutes a very rare entity in children and adolescents that is most commonly observed in postpubertal girls with ovarian teratoma.
  • Compared to adult patients, similar malignant entities can be observed in association with teratoma.
  • In localised tumors, complete resection appears to be adequate, whereas chemotherapy should be considered in patients with R1- or R2-resection.
  • Cisplatinum-based chemotherapy was effective as two of four relapsed patients survived tumor free.
  • However, the ideal regimen has not yet been established and the known sensitivity of the histologic components to cytostatic drugs has to be considered in the choice of treatment.
  • [MeSH-major] Ovarian Neoplasms. Teratoma
  • [MeSH-minor] Adolescent. Adult. Age Factors. Antineoplastic Combined Chemotherapy Protocols. Chemotherapy, Adjuvant. Child. Child, Preschool. Cytogenetic Analysis. Female. Humans. Infant. Infant, Newborn. Middle Aged. Neoplasm Staging. Neoplasms, Germ Cell and Embryonal / pathology. Ovary / pathology. Sacrococcygeal Region / pathology. Treatment Outcome

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  • (PMID = 17080331.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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6. Mann JR, Gray ES, Thornton C, Raafat F, Robinson K, Collins GS, Gornall P, Huddart SN, Hale JP, Oakhill A, UK Children's Cancer Study Group Experience: Mature and immature extracranial teratomas in children: the UK Children's Cancer Study Group Experience. J Clin Oncol; 2008 Jul 20;26(21):3590-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: The purpose of this article is to describe the features, treatment, and risk factors for relapse of children with mature teratoma (MT) and immature teratoma (IT) to assist future treatment plans.
  • PATIENTS AND METHODS: Patients were younger than 16 years of age and referred to the UK Children's Cancer Study Group centers with biopsy-proven extracranial MT and IT and no prior chemotherapy.
  • Complete excision, with the coccyx in sacrococcygeal patients, and follow-up, including serum alpha-fetoprotein monitoring for early detection of malignant yolk sac tumor (YST) recurrence, were recommended.
  • Pathology was reviewed and treatments, outcome, and prognostic features assessed.
  • Tumor sites were: testis (n = 53), ovary (n = 130), sacrococcygeal region (n = 98), thorax (n = 23), and other (n = 47).
  • Poorer outcome occurred with incomplete resection, tumor rupture, nongonadal site (particularly sacrococcygeal), young age, higher stage and grade, and gliomatosis peritonei, but not with cyst fluid aspiration/spillage, tumor enucleation, nodal gliomatosis, or microfoci of YST in the tumor (Heifetz lesions).
  • CONCLUSION: Treatment remains primarily surgical, with JEB chemotherapy for YST relapse.
  • Adjuvant chemotherapy after surgery for sacrococcygeal patients is not advocated.
  • [MeSH-major] Neoplasm Recurrence, Local / epidemiology. Teratoma / pathology. Teratoma / surgery
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Child. Child, Preschool. Disease-Free Survival. Female. Great Britain. Humans. Infant. Male. Risk Factors

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  • (PMID = 18541896.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United Kingdom / Cancer Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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7. Lukaszewski T, Połczyńska-Kaniak E, Puacz P, Seremak-Mrozikiewicz A, Drews K: [Sacrococcygeal teratoma in foetus--case report]. Ginekol Pol; 2009 Nov;80(11):861-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sacrococcygeal teratoma in foetus--case report].
  • Sacrococcygeal teratoma develops from all three germinal layers (endoderm, mesoderm and ectoderm).
  • Sacrococcygeal teratomas (SCT) are the most common neoplasms in the fetus and newborns, with an estimated prevalence of 1 in 20,000 to 1 in 40,000.
  • According to Polish Gynecology Society Recommendation, the main aim of intrauterine intervention or pharmacological treatment in case of prenatally diagnosed SCT is to prevent development of severe fetal cardiac failure.
  • The following article describes a case report of a 34-year-old pregnant woman, 23 weeks of gestation, with a diagnosis of fetal sacrococcygeal teratoma.
  • Each pregnant woman with suspicion of neoplasm in fetus should be referred to tertiary center of perinatal care to gain access to specific diagnostic methods and medical care of many specialists, such as obstetricians, neonatologists, general practitioners and infant surgeons.
  • [MeSH-major] Abortion, Eugenic. Congenital Abnormalities / diagnostic imaging. Sacrococcygeal Region / diagnostic imaging. Spinal Neoplasms / diagnostic imaging. Teratoma / diagnostic imaging
  • [MeSH-minor] Adult. Fatal Outcome. Female. Humans. Pregnancy. Pregnancy Trimester, Second. Prenatal Diagnosis. Ultrasonography


8. Huddart SN, Mann JR, Robinson K, Raafat F, Imeson J, Gornall P, Sokal M, Gray E, McKeever P, Oakhill A, Children's Cancer Study Group: Sacrococcygeal teratomas: the UK Children's Cancer Study Group's experience. I. Neonatal. Pediatr Surg Int; 2003 Apr;19(1-2):47-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sacrococcygeal teratomas: the UK Children's Cancer Study Group's experience. I. Neonatal.
  • The aim of this study was to review the United Kingdom Children's Cancer Study Group (UKCCSG) experience of sacrococcygeal teratomas (SCT) including histological presentation, response to surgery and chemotherapy, and long term effects of the tumour and treatment.
  • Children aged up to 4 weeks with biopsy proven localised or metastatic sacrococcygeal germ cell tumours were eligible.
  • These children received chemotherapy in the form of etoposide/bleomycin/carboplatin (JEB) and are alive and well at review.
  • These results emphasise the need for oncological follow-up of SCT and the good response to JEB chemotherapy of malignant teratomas and YST.
  • [MeSH-major] Sacrococcygeal Region / pathology. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / therapy. Teratoma / diagnosis. Teratoma / therapy
  • [MeSH-minor] Female. Great Britain / epidemiology. Humans. Incidence. Infant, Newborn. Male. Neoplasm Staging. Prognosis. Treatment Outcome

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  • (PMID = 12721723.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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9. Groff DB: Pelvic neoplasms in children. J Surg Oncol; 2001 May;77(1):65-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The most common neoplasms are rhabdomyosarcomas of the bladder, prostate, and vagina; sacrococcygeal teratoma; and the germ cell tumors, including teratomas, endodermal sinus tumors, and the choriocarcinomas.
  • Rapidly improving chemotherapy for all of these lesions has resulted in a changed role for the surgeon.
  • Survival for all types of childhood pelvic neoplasms has improved dramatically under the influence of the combined children's cancer study groups, which have been functioning for the last 20 years.
  • Because of the complexities of diagnosis and treatment of these pelvic neoplasms in childhood and because the survival rates have dramatically improved with the most current therapy, these children should be cared for in a children's center that is part of the major children's cancer study groups.

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  • [Copyright] Copyright 2001 Wiley-Liss, Inc.
  • (PMID = 11344486.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 36
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10. Billmire DF: Malignant germ cell tumors in childhood. Semin Pediatr Surg; 2006 Feb;15(1):30-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A review of the cooperative studies on malignant extracranial germ cell tumors in children was performed to update the progress in treatment and outcome for this rare group of tumors.
  • The advent of platinum-based chemotherapy in the 1980s dramatically improved the prognosis for these tumors and allowed redefinition of risk groups.
  • Chemotherapy regimens have been sequentially modified to reduce toxicity while maintaining survival.
  • Surgical management has evolved from an aggressive en bloc resection at diagnosis to a more tailored approach, with resection and meticulous staging for low stage tumors at diagnosis and biopsy with neoadjuvant chemotherapy for advanced stage tumors.
  • Improved surgical margins and prognosis are seen in post chemotherapy resections for high stage tumors.
  • Large persisting masses after chemotherapy are often due to coexisting elements of benign teratoma, and aggressive attempts at resection are warranted in these patients with expectation of successful outcome.
  • [MeSH-major] Neoplasms, Germ Cell and Embryonal / diagnosis. Neoplasms, Germ Cell and Embryonal / therapy
  • [MeSH-minor] Child. Female. Humans. Male. Mediastinal Neoplasms / diagnosis. Mediastinal Neoplasms / mortality. Mediastinal Neoplasms / therapy. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Neoplasms / mortality. Retroperitoneal Neoplasms / therapy. Sacrococcygeal Region. Survival Rate. Urogenital Neoplasms / diagnosis. Urogenital Neoplasms / mortality. Urogenital Neoplasms / therapy

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  • (PMID = 16458844.001).
  • [ISSN] 1055-8586
  • [Journal-full-title] Seminars in pediatric surgery
  • [ISO-abbreviation] Semin. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 35
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11. Schneider DT, Wessalowski R, Calaminus G, Pape H, Bamberg M, Engert J, Waag K, Gadner H, Göbel U: Treatment of recurrent malignant sacrococcygeal germ cell tumors: analysis of 22 patients registered in the German protocols MAKEI 83/86, 89, and 96. J Clin Oncol; 2001 Apr 01;19(7):1951-60
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of recurrent malignant sacrococcygeal germ cell tumors: analysis of 22 patients registered in the German protocols MAKEI 83/86, 89, and 96.
  • PURPOSE: To evaluate therapeutic options for recurrent malignant sacrococcygeal germ cell tumors (GCT) following three-agent, cisplatinum-based, first-line chemotherapy and tumor resection.
  • One patient, who relapsed with pure teratoma, was excluded from the analysis of adjuvant treatment.
  • Twelve patients achieved complete remission (CR) after surgery (n = 12) and adjuvant platinum chemotherapy (n = 10).
  • All patients who achieved only a partial remission developed a second relapse.
  • Altogether, 10 patients survived disease free, and 12 patients died as a result of tumor progression (n = 11) or therapy-related complications (n = 1).
  • The completeness of salvage surgery and clinical remission status after first salvage treatment were the most important prognostic parameters.
  • In addition, patients in first or second relapse with locally advanced or poorly responding tumors benefited from preoperative chemotherapy in combination with regional hyperthermia (RHT).
  • In some patients after microscopically incomplete resection, irradiation at doses > 45 Gy contributed to a favorable outcome.
  • CONCLUSION: The complete resection of the local recurrence represents the cornerstone of salvage treatment.
  • Preoperative platinum-based chemotherapy, combined with RHT in some patients, facilitates complete tumor resection.
  • As the chance of cure decreases with further relapses, it is important to establish a stringent therapeutic strategy to avoid significant treatment delays and, most importantly, insufficient local therapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Neoplasm Recurrence, Local / therapy. Neoplasms, Germ Cell and Embryonal / therapy. Salvage Therapy / methods
  • [MeSH-minor] Actuarial Analysis. Algorithms. Child. Cisplatin / administration & dosage. Combined Modality Therapy. Follow-Up Studies. Germany / epidemiology. Humans. Infant, Newborn. Prognosis. Radiotherapy. Sacrococcygeal Region. Statistics, Nonparametric

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  • (PMID = 11283127.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin
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12. Ozkan KU, Bauer SB, Khoshbin S, Borer JG: Neurogenic bladder dysfunction after sacrococcygeal teratoma resection. J Urol; 2006 Jan;175(1):292-6; discussion 296
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neurogenic bladder dysfunction after sacrococcygeal teratoma resection.
  • PURPOSE: SCT treatment in newborns consists of surgery and selective chemotherapy.
  • This review focuses on the urological and neurourological findings following SCT treatment in the newborn period.
  • At the time of UDS an abnormal neurological examination was noted in 5 patients (36%).
  • CONCLUSIONS: SCT and its treatment can produce neurourological dysfunction of the lower urinary tract with high grade reflux, and abnormal bladder and urethral function.
  • [MeSH-major] Postoperative Complications / etiology. Teratoma / surgery. Urinary Bladder, Neurogenic / etiology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Male. Retrospective Studies. Sacrococcygeal Region


13. Isaacs H Jr: Perinatal (fetal and neonatal) germ cell tumors. J Pediatr Surg; 2004 Jul;39(7):1003-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of this study is to focus on the fetus and neonate in an attempt to determine the various ways germ cell tumors differ clinically and morphologically from those occurring in the older child and adult and to show that certain types of tumors have a better prognosis than others.
  • The incidence of teratoma with yolk sac tumor either at presentation or at recurrence was 5.8%, and the survival rate was 39%.
  • Sacrococcygeal teratomas had the highest incidence of yolk sac tumor at 10%.
  • Recurrent disease in the form of either teratoma or yolk sac tumor developed in 5% of patients.
  • Fetuses with teratomas detected antenatally have 3 times the mortality rate compared with postnatally diagnosed neonates.
  • Surgical resection alone may be adequate therapy for teratomas with nonmetastatic, microscopic foci of yolk sac tumor.
  • Currently, the use of platinum-based combination chemotherapy has significantly improved the survival rate of infants with advanced malignant germ cell tumor disease.
  • [MeSH-minor] Brain Neoplasms / epidemiology. Comorbidity. Digestive System Neoplasms / epidemiology. Endodermal Sinus Tumor / epidemiology. Female. Humans. Infant. Infant, Newborn. Los Angeles / epidemiology. Male. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Sacrococcygeal Region. Spinal Neoplasms / epidemiology. Survival Rate. Teratoma / epidemiology. Ultrasonography, Prenatal

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  • (PMID = 15213888.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Costa C, Rocha G, Grilo M, Bianchi R, Sotto Mayor T, Monteiro J, Guimarães H: [Neonatal tumors]. Acta Med Port; 2010 May-Jun;23(3):405-12
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  • INTRODUCTION: Tumors affecting the fetus and newborn differ from those found in older children and adults, leading to new diagnostic and therapeutic challenges.
  • MATERIAL AND METHODS: Retrospective analysis of clinical data from newborn patients admitted to the Service of Neonatology of São João Hospital between 1996 and 2006, with the diagnosis of tumor or neoplasia.
  • RESULTS: Total = 32 cases, 16M/16F, birth weight: 3146 g (965-4590), gestational age 38 weeks (28-41), seven (22%) preterm, C-section rate 75% (n = 24), two with EXIT procedure.
  • DIAGNOSIS: Teratoma (n = 8); lymphangioma (n = 7), neuroblastoma (n = 6), haemangioma (n = 5), other solid tumors (n = 6); acute lymphoblastic leukemia (n = 1).
  • Prenatal diagnosis 50% (n = 16).
  • Teratoma: immature (n = 3); mature (n = 5), sacrococcygeal location (n = 5); cervical (n = 3); total macroscopic resection (n = 8).
  • Chemotherapy (n = 5), according to the <<European Infant Neuroblastoma Study>> (n = 2), surgical resection (n = 4).
  • OTHER SOLID TUMORS: Large haemangiomas (n = 5); scaly papiloma (n = 1); juvenile xanthogranuloma (n = 1); lipoblastoma (n = 1); nephroma (n = 1); nonclassified neoplasm, possible nervous sheath sarcoma (n = 1).
  • COMMENT: Pre-natal diagnosis allows the planning of a careful multidisciplinary approach.

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  • (PMID = 20654259.001).
  • [ISSN] 1646-0758
  • [Journal-full-title] Acta médica portuguesa
  • [ISO-abbreviation] Acta Med Port
  • [Language] por
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Portugal
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15. Howman-Giles R, Holland AJ, Mihm D, Montfort JM, Arbuckle S, Kellie S: Somatic malignant transformation in a sacrococcygeal teratoma in a child and the use of F18FDG PET imaging. Pediatr Surg Int; 2008 Apr;24(4):475-8
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  • [Title] Somatic malignant transformation in a sacrococcygeal teratoma in a child and the use of F18FDG PET imaging.
  • Biopsy revealed an adenocarcinoma most likely arising from a sacrococcygeal teratoma (SCT).
  • F(18)FDG Positron Emission Tomography (PET) scan confirmed marked metabolic activity in the tumour mass and regional lymph node involvement.
  • After chemotherapy repeat CT and PET studies revealed a poor response but no evidence of peritoneal or distant metastases.
  • Radical abdomino-pelvic and gluteal surgery was performed with removal of the entire tumour confirmed as a moderately differentiated adenocarcinoma arising in an immature teratoma.
  • [MeSH-major] Adenocarcinoma. Fluorodeoxyglucose F18. Neoplasms, Multiple Primary. Positron-Emission Tomography. Radiopharmaceuticals. Teratoma
  • [MeSH-minor] Cell Transformation, Neoplastic / pathology. Child. Female. Humans. Sacrococcygeal Region. Treatment Outcome

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  • [Cites] Br J Radiol. 2002 Jul;75(895):620-3 [12145137.001]
  • [Cites] J Pediatr Surg. 2004 Jul;39(7):1003-13 [15213888.001]
  • [Cites] Eur J Pediatr Surg. 1997 Jun;7(3):152-5 [9241501.001]
  • [Cites] J Pediatr Surg. 1992 Aug;27(8):1075-8; discussion 1078-9 [1403540.001]
  • [Cites] J Nucl Med. 2007 Jan;48 Suppl 1:78S-88S [17204723.001]
  • [Cites] J Pediatr Surg. 2006 Sep;41(9):1513-6 [16952583.001]
  • [Cites] Med Pediatr Oncol. 1998 Jul;31(1):8-15 [9607423.001]
  • [Cites] Ann Oncol. 2000 Mar;11(3):263-71 [10811491.001]
  • [Cites] J Pediatr Surg. 1992 Nov;27(11):1447-50 [1282543.001]
  • [Cites] Pediatr Surg Int. 2002 Sep;18(5-6):384-7 [12415361.001]
  • [Cites] J Clin Oncol. 1999 Apr;17(4):1212 [10561181.001]
  • [Cites] J Pediatr Surg. 1998 Feb;33(2):171-6 [9498381.001]
  • [Cites] J Urol. 1998 Mar;159(3):859-63 [9474169.001]
  • [Cites] J Urol. 1994 Oct;152(4):1144-9 [8072083.001]
  • [Cites] BMJ. 2004 Apr 24;328(7446):1002-6 [15105327.001]
  • [Cites] Cancer. 1995 Jun 1;75(11):2663-8 [7743467.001]
  • [Cites] J Urol. 1998 Jan;159(1):133-8 [9400455.001]
  • [Cites] J Clin Oncol. 1986 Oct;4(10):1493-9 [2428948.001]
  • [Cites] J Pediatr Surg. 1974 Jun;9(3):389-98 [4843993.001]
  • [Cites] J Clin Oncol. 1991 Oct;9(10):1782-92 [1717667.001]
  • [Cites] Cancer. 1985 Aug 15;56(4):860-3 [2990657.001]
  • [Cites] Int J Gynecol Pathol. 2002 Jul;21(3):261-7 [12068172.001]
  • [Cites] Pediatr Surg Int. 2003 Apr;19(1-2):47-51 [12721723.001]
  • [Cites] Cancer. 1992 Nov 15;70(10):2568-75 [1384951.001]
  • [Cites] Eur J Nucl Med Mol Imaging. 2005 Jan;32(1):23-30 [15290124.001]
  • (PMID = 17828545.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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16. Khalil BA, Aziz A, Kapur P, Humphrey G, Morabito A, Bruce J: Long-term outcomes of surgery for malignant sacrococcygeal teratoma: 20-year experience of a regional UK centre. Pediatr Surg Int; 2009 Mar;25(3):247-50
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  • [Title] Long-term outcomes of surgery for malignant sacrococcygeal teratoma: 20-year experience of a regional UK centre.
  • BACKGROUND: The timing of surgery for malignant sacrococcygeal teratoma is controversial.
  • METHODS: All cases of malignant sacrococcygeal teratoma in the 20-year period 1987-2006 were identified and the case notes retrieved.
  • The age at diagnosis, investigations, presentation, type of surgery, early complications, recurrence rates, long-term complications and outcomes were recorded.
  • The average time of follow-up was 10.6 years (range: 1-17 years).
  • Ten patients had excision of their tumours following chemotherapy, whilst two patients had excision prior to chemotherapy.
  • CONCLUSION: Surgery for malignant sacrococcygeal teratoma is safe and has a low complication rate.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Spinal Neoplasms / surgery. Teratoma / surgery
  • [MeSH-minor] Bleomycin / administration & dosage. Carboplatin / administration & dosage. Child, Preschool. Etoposide / administration & dosage. Female. Follow-Up Studies. Humans. Infant. Male. Neoadjuvant Therapy. Sacrococcygeal Region. Treatment Outcome. United Kingdom

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  • [Cites] J Clin Oncol. 2003 Mar 1;21(5):781-6 [12610174.001]
  • [Cites] J Pediatr Surg. 1981 Aug;16(4 Suppl 1):573-7 [7277158.001]
  • [Cites] Pediatr Surg Int. 2008 Apr;24(4):475-8 [17828545.001]
  • [Cites] Eur J Pediatr Surg. 1997 Jun;7(3):152-5 [9241501.001]
  • [Cites] Pathology. 1992 Oct;24(4):247-53 [1289765.001]
  • [Cites] J Pediatr Surg. 2006 Sep;41(9):1513-6 [16952583.001]
  • [Cites] J Clin Oncol. 2001 Apr 1;19(7):1943-50 [11283126.001]
  • [Cites] J Clin Oncol. 2008 Jul 20;26(21):3590-7 [18541896.001]
  • [Cites] J Clin Oncol. 2001 Apr 1;19(7):1951-60 [11283127.001]
  • [Cites] J Pediatr Surg. 2006 Jan;41(1):173-81; discussion 173-81 [16410129.001]
  • [Cites] Br J Surg. 2006 Dec;93(12):1543-8 [17058315.001]
  • [Cites] Pediatr Surg Int. 1999;15(8):573-6 [10631738.001]
  • [Cites] Pediatr Surg Int. 2003 Apr;19(1-2):47-51 [12721723.001]
  • [Cites] Semin Pediatr Surg. 2006 Feb;15(1):30-6 [16458844.001]
  • (PMID = 19184053.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; BG3F62OND5 / Carboplatin; JEB protocol
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17. Song JS, Kim IK, Kim YM, Khang SK, Kim KR, Lee Y: Extrarenal teratoid Wilms' tumor: two cases in unusual locations, one associated with elevated serum AFP. Pathol Int; 2010 Jan;60(1):35-41
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  • Teratoid Wilms' tumor is an unusual morphological entity characterized by a classic triphasic malignancy with predominantly heterologous tissue.
  • The authors describe two cases of teratoid Wilms' tumor with an extrarenal site: one in a 13-year-old girl with vaginal spotting (patient 1) and another in a 1-day-old girl with a sacrococcygeal mass (patient 2).
  • Under the initial clinical diagnosis of sarcoma botryoides in patient 1 and teratoma in patient 2, the masses were removed.
  • Microscopically, both tumors were composed of typical triphasic Wilms' tumor tissue with primitive cartilage and skeletal muscle, and squamous and columnar mucinous epithelia.
  • The patient with sacrococcygeal mass (patient 2) had an elevated serum AFP level.
  • The patients were given chemotherapy and have now remained disease free for 7 years 1 month, and 2 years 5 months after surgery, respectively.
  • Familiarity with this rare variant of Wilms' tumor might be important in arriving at a correct diagnosis.
  • [MeSH-minor] Adolescent. Antineoplastic Agents / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Dactinomycin / therapeutic use. Disease-Free Survival. Female. Humans. Infant, Newborn. Pregnancy. Prenatal Diagnosis. Teratoma / drug therapy. Teratoma / pathology. Teratoma / surgery. Vincristine / therapeutic use

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  • (PMID = 20055950.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / alpha-Fetoproteins; 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide
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18. Ghazi L, Ko F, Bathgate SL, Larsen JW, Macri C: Rapid growth of a fetal sacrococcygeal teratoma in an HIV-infected woman: a case report. J Reprod Med; 2006 May;51(5):431-4
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  • [Title] Rapid growth of a fetal sacrococcygeal teratoma in an HIV-infected woman: a case report.
  • BACKGROUND: Sacrococcygeal teratoma, the most common congenital neoplasm of the newborn, associated with fetal hydrops and high morbidity and mortality related to the secondary effects of the tumor mass, is of unknown etiology.
  • Prompt diagnosis and early treatment have proven to be effective.
  • CASE: A 24-year-old woman, gravida 3, para 2, at 385/7 weeks' gestation, with a pregnancy complicated by HIV diagnosed during pregnancy, seizure disorder and tobacco use, presented with premature rupture of membranes.
  • CONCLUSION: This is the first case report to describe a rapidly growing sacrococcygeal teratoma in a neonate from a pregnancy complicated by HIV.
  • Further research concerning sacrococcygeal teratoma and HIV in pregnancy is necessary for prompt and early diagnosis and treatment of antepartum and peripartum complications.
  • [MeSH-major] HIV Infections / drug therapy. Pregnancy Complications, Infectious / drug therapy. Sacrococcygeal Region / surgery. Teratoma / surgery
  • [MeSH-minor] Adult. Cesarean Section. Female. Fetal Diseases / etiology. HIV Seropositivity. Humans. Infant, Newborn. Laparoscopy. Pregnancy. Seizures / drug therapy. Seizures / prevention & control. Smoking


19. Terenziani M, D'Angelo P, Bisogno G, Boldrini R, Cecchetto G, Collini P, Conte M, De Laurentis T, Ilari I, Indolfi P, Inserra A, Piva L, Siracusa F, Spreafico F, Tamaro P, Lo Curto M: Teratoma with a malignant somatic component in pediatric patients: the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience. Pediatr Blood Cancer; 2010 Apr;54(4):532-7
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  • [Title] Teratoma with a malignant somatic component in pediatric patients: the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) experience.
  • BACKGROUND: Teratoma with a malignant somatic component (TMSC) is rare but described in adults, whereas information on pediatric presentation is sparse.
  • PROCEDURE: The Associazione Italiana Ematologia Oncologia Pediatrica identified 14 cases of TMSC.
  • RESULTS: The series (9 female, 5 male) showed the following disease: testis (2), sacrococcygeal (3), ovary (3), retroperitoneum (3), mediastinum (2), and foot soft tissue (1).
  • Chemotherapy optimized for histology should include reagents directed to the somatic malignancy, if chemosensitive.
  • Malignant GCT warrants GCT-directed chemotherapy.
  • [MeSH-major] Teratoma / pathology
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Infant, Newborn. Italy. Male. Neoplasm Staging. Prognosis. Retrospective Studies. Treatment Outcome


20. Wakhlu A, Misra S, Tandon RK, Wakhlu AK: Sacrococcygeal teratoma. Pediatr Surg Int; 2002 Sep;18(5-6):384-7
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  • [Title] Sacrococcygeal teratoma.
  • This retrospective study details our experience regarding 72 patients with sacrococcygeal teratoma treated over a period of 17 years.
  • The sex incidence was nearly equal, but there was a high proportion of Altmann type IV tumors.
  • A preliminary colostomy before combined abdominosacral excision of large type III and IV lesions reduced morbidity.
  • Imaging studies included radiography, abdominal ultrasound, computed tomography, and magnetic resonance imaging (after 1995).
  • Eight had a preliminary colostomy and chemotherapy followed by excision of the residual tumor and colostomy closure.
  • Of the latter 11 (who received cisplatinum-based chemotherapy), 10 were alive 1 year after surgery.
  • One patient is currently on preoperative chemotherapy and another developed recurrence of the tumor.
  • As intrapelvic tumors tend to have a delayed diagnosis, this can be avoided by performing a rectal examination.
  • There should be no recurrence after excision of a benign teratoma.
  • Cisplatinum-based chemotherapy has improved the survival of patients with malignant tumors.
  • [MeSH-major] Teratoma / surgery
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Magnetic Resonance Imaging. Male. Retrospective Studies. Sacrococcygeal Region

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  • (PMID = 12415361.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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21. Chan KL, Tang MH, Tse HY, Tang RY, Lam HS, Lee CP, Tam PK: Factors affecting outcomes of prenatally-diagnosed tumours. Prenat Diagn; 2002 May;22(5):437-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: Medical records of all fetuses referred to our institutions with antenatally-diagnosed tumours were reviewed for the type and location of the tumours, results of treatment and/or causes of death.
  • RESULTS: From January 1994 to May 2001, there were 15 fetuses with antenatally- diagnosed tumours: mesoblastic nephroma (MN) (n=2); neuroblastoma (NB) (n=2); cystic hygroma (CH) (n=3); intracranial germ cell tumour (IGCT) (n=2); sacrococcygeal teratoma (SCT) (n=3) and haemangioma (liver, n=2; limb, n=1).
  • One baby had cardiac failure resulting from a lower limb haemangioma and needed drug therapy.
  • All solid tumours (MN, NB, SCT) of the live births had no recurrence after surgery with or without adjuvant chemotherapy.
  • [MeSH-minor] Adult. Female. Gestational Age. Humans. Pregnancy. Retrospective Studies. Survival Analysis. Survival Rate. Treatment Outcome

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  • [Copyright] Copyright 2002 John Wiley & Sons, Ltd.
  • (PMID = 12001204.001).
  • [ISSN] 0197-3851
  • [Journal-full-title] Prenatal diagnosis
  • [ISO-abbreviation] Prenat. Diagn.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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22. Unal E, Koksal Y, Toy H, Gunel E, Acikgozoglu S: Neuroblastoma arising from an unresected sacrococcygeal teratoma in a child. J Pediatr Hematol Oncol; 2010 Apr;32(3):233-5
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  • [Title] Neuroblastoma arising from an unresected sacrococcygeal teratoma in a child.
  • The authors report a case of malignant transformation of an unreseceted sacrococcygeal teratoma to neuroblastoma in a 6-year-old girl and discuss this case in the light of relevant literature.
  • In addition, when malignant transformation occurs, the treatment strategy must include surgery together with histology adapted systemic chemotherapy.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Neuroblastoma / pathology. Sacrococcygeal Region / pathology. Spinal Neoplasms / pathology. Teratoma / pathology


23. Tanaka K, Kanai M, Yosizawa J, Yamazaki Y: A case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma. J Pediatr Surg; 2005 Mar;40(3):578-80
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  • [Title] A case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma.
  • The authors report a case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma.
  • A newborn male infant delivered after a normal pregnancy was found to have an extremely large sacrococcygeal mass.
  • Imaging studies strongly suggested Altman type III sacrococcygeal teratoma.
  • The tumor disappeared completely after chemotherapy.
  • One year after diagnosis, no local recurrence or metastasis had been detected.
  • To the authors' knowledge, this is the first case of neonatal neuroblastoma mimicking Altman type III sacrococcygeal teratoma.
  • [MeSH-major] Neuroblastoma / diagnosis. Soft Tissue Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Calcinosis / diagnosis. Colostomy. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Humans. Infant, Newborn. Magnetic Resonance Imaging. Male. Phosphopyruvate Hydratase / analysis. Rectum / pathology. Rectum / surgery. Remission Induction. Sacrococcygeal Region. Subcutaneous Tissue. Synaptophysin / analysis. Vincristine / administration & dosage

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  • (PMID = 15793740.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Synaptophysin; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; EC 4.2.1.11 / Phosphopyruvate Hydratase
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24. Yalçin B, Kutluk MT, Ariyürek M, Göğüş S, Büyükpamukçu M: Metastatic endodermal sinus tumor: CT appearances. Turk J Pediatr; 2002 Oct-Dec;44(4):343-5
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  • A one-week-old boy had undergone resection of a sacrococcygeal benign cystic teratoma.
  • Postoperatively, massively enlarged inguinal lymph nodes and abdominal distention developed.
  • Computerized tomography displayed enlarged inguinal lymph nodes, metastatic lesions in the liver, and a pelvic recurrent mass.
  • He received BEP (bleomycin, etoposide, cisplatin) chemotherapy regimen, and a complete remission was achieved with a normal serum alpha-fetoprotein.
  • Close follow-up and serum alpha-fetoprotein monitoring are mandatory after the resection of a sacrococcygeal teratoma.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / therapeutic use. Cisplatin / therapeutic use. Combined Modality Therapy. Etoposide / therapeutic use. Humans. Infant. Male. Sacrococcygeal Region. Tomography, X-Ray Computed. alpha-Fetoproteins / analysis

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  • (PMID = 12458813.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / alpha-Fetoproteins; 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; BEP protocol
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25. Lo Curto M, D'Angelo P, Cecchetto G, Klersy C, Dall'Igna P, Federico A, Siracusa F, Alaggio R, Bernini G, Conte M, De Laurentis T, Di Cataldo A, Inserra A, Santoro N, Tamaro P, Indolfi P: Mature and immature teratomas: results of the first paediatric Italian study. Pediatr Surg Int; 2007 Apr;23(4):315-22
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  • Teratoma is the most common germ cell tumour in childhood; mature (MT) and immature teratomas (IT) are benign tumours, but if they recur, they can be in some cases malignant.
  • Clinical data, treatment and results were all analysed.
  • Chemotherapy (CT) with Vinblastine, D: -actinomycin and cyclophosphamide was indicated for extra-testicular IT grade 2 or 3.
  • MT was diagnosed in 127 patients (93 F and 34 M, age 1-192 months, median 24): 58 patients had gonadic tumour (23 testicular, 35 ovaric), 69 extragonadic (45 sacrococcygeal, 11 mediastinic, 7 retroperitoneal, 6 in other sites).
  • The T grading was 1 in 14 cases, 2 in 26, 3 in 16; 28 had gonadic T (17 ovary, 11 testis), 28 extragonadic (sacrococcygeal 19, mediastinic 3, retroperitoneal 2, other sites 4).
  • Seven MT (5.5%) relapsed (five sacrococcygeal, one retroperitoneal, one mediastinic): surgery at diagnosis had been complete in five and with residual in two; the relapse was malignant in two patients with sacrococcygeal (sc) tumours, who had a complete resection and a partial resection respectively.
  • [MeSH-major] Ovarian Neoplasms / epidemiology. Teratoma / epidemiology. Testicular Neoplasms / epidemiology
  • [MeSH-minor] Age Distribution. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Incidence. Infant. Infant, Newborn. Italy / epidemiology. Male. Neoplasm Staging. Prospective Studies

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  • [Cites] Klin Padiatr. 1997 Jul-Aug;209(4):228-34 [9293455.001]
  • [Cites] J Pediatr Surg. 2001 Jan;36(1):12-7 [11150431.001]
  • [Cites] J Clin Oncol. 1999 Jul;17(7):2137-43 [10561269.001]
  • [Cites] Med Pediatr Oncol. 2003 Nov;41(5):417-25 [14515380.001]
  • [Cites] J Pediatr Surg. 1992 Aug;27(8):1075-8; discussion 1078-9 [1403540.001]
  • [Cites] J Clin Oncol. 1997 Feb;15(2):620-4 [9053485.001]
  • [Cites] J Pediatr Surg. 1987 Mar;22(3):274-7 [3559872.001]
  • [Cites] Med Pediatr Oncol. 1998 Jul;31(1):8-15 [9607423.001]
  • [Cites] Ann Surg. 1965 Dec;162(6):1091-5, 1100 [5845591.001]
  • [Cites] Crit Rev Oncol Hematol. 1990;10(2):99-110 [2163259.001]
  • [Cites] J Pediatr Surg. 1998 Feb;33(2):171-6 [9498381.001]
  • [Cites] Cancer. 1989 May 1;63(9):1657-67 [2467734.001]
  • [Cites] Pediatr Blood Cancer. 2004 Feb;42(2):169-75 [14752882.001]
  • [Cites] Crit Rev Oncol Hematol. 1990;10(2):89-98 [1694438.001]
  • [Cites] Med Pediatr Oncol. 1993;21(6):395-401 [8390599.001]
  • [Cites] Am J Obstet Gynecol. 1999 Aug;181(2):353-8 [10454682.001]
  • [Cites] J Pediatr Surg. 1974 Jun;9(3):389-98 [4843993.001]
  • [Cites] Cancer. 1976 May;37(5):2359-72 [1260722.001]
  • [Cites] AJR Am J Roentgenol. 1981 Aug;137(2):395-8 [6789651.001]
  • (PMID = 17333214.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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26. Chirdan LB, Uba AF, Pam SD, Edino ST, Mandong BM, Chirdan OO: Sacrococcygeal teratoma: clinical characteristics and long-term outcome in Nigerian children. Ann Afr Med; 2009 Apr-Jun;8(2):105-9
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  • [Title] Sacrococcygeal teratoma: clinical characteristics and long-term outcome in Nigerian children.
  • BACKGROUND/PURPOSE: The excision of sacrococcygeal teratoma (SCT) may be associated with significant long-term morbidity for the child.
  • METHODS: Between January 1990 and May 2008 inclusive, 38 consecutive children with the diagnosis of SCT were identified from the operation register and the Cancer Registry of the Jos University Teaching Hospital.
  • Four children with malignant disease had chemotherapy in addition to excision of the tumor.
  • [MeSH-major] Coccyx. Sacrum. Spinal Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Developing Countries. Female. Humans. Infant. Infant, Newborn. Male. Nigeria / epidemiology. Prevalence. Prognosis. Retrospective Studies. Sacrococcygeal Region. Sex Factors

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  • (PMID = 19805941.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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27. Yang WP, Zou Y, Huang CS, Zhang SZ, Xiao Q, Dai KL, Zhong HS, Xiong XJ: [Clinicopathologic and prognostic study of pediatric immature teratoma]. Zhonghua Bing Li Xue Za Zhi; 2007 Oct;36(10):666-71
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  • [Title] [Clinicopathologic and prognostic study of pediatric immature teratoma].
  • OBJECTIVE: To study the clinicopathologic features and biologic behavior of pediatric immature teratoma.
  • METHODS: The clinical data, pathologic features, immunohistochemical findings (for cyclin D1, P27 and Ki-67) and follow-up information of 39 cases of pediatric immature teratoma were analyzed.
  • RESULTS: Amongst the 39 cases studied, 12 arose in the sacrococcygeal region, 12 in testis, 5 in retroperitoneum, 4 in ovary, 4 in abdomen and 2 in mediastinum.
  • Immature neuroepithelial features used in histologic grading included the presence of primitive neural tubules, immature rosettes, undifferentiated neuroblastoma cells and primitive neuroectodermal structures.
  • The prognosis of immature teratoma in children is different from that in adults.
  • Sacrococcygeal immature teratoma occurring in patients younger than 1 year old and with low histologic grade do not require postoperative chemotherapy if the tumor is completely excised.
  • Similarly, for testicular immature teratoma occurring in patients below 1 year of age, regardless of tumor grading, need no adjunctive therapy.
  • On the other hand, ovarian immature teratoma with high histologic grade requires postoperative chemotherapy, regardless of age of the patients.
  • The presence of microscopic foci of yolk sac tumor is a useful predictor of recurrence in pediatric immature teratoma.
  • [MeSH-major] Ovarian Neoplasms / pathology. Retroperitoneal Neoplasms / pathology. Teratoma / pathology. Testicular Neoplasms / pathology
  • [MeSH-minor] Adolescent. Cyclin D1 / metabolism. Endodermal Sinus Tumor / drug therapy. Endodermal Sinus Tumor / metabolism. Endodermal Sinus Tumor / pathology. Endodermal Sinus Tumor / surgery. Female. Follow-Up Studies. Humans. Infant. Infant, Newborn. Ki-67 Antigen / metabolism. Male. Mediastinal Neoplasms / drug therapy. Mediastinal Neoplasms / metabolism. Mediastinal Neoplasms / pathology. Mediastinal Neoplasms / surgery. Neoplasm Recurrence, Local. Neoplasm Staging. Proliferating Cell Nuclear Antigen / metabolism. Sacrococcygeal Region. Survival Rate. alpha-Fetoproteins / metabolism

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  • (PMID = 18194599.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Proliferating Cell Nuclear Antigen; 0 / alpha-Fetoproteins; 0 / p27 antigen; 136601-57-5 / Cyclin D1
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28. Elli M, Pinarli FG, Kandemir B, Dagdemir A, Ceyhan M, Acar S: Sacrococygeal teratoma with sarcomatous differentiation in a child. Pediatr Hematol Oncol; 2008 Jun;25(4):345-50
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  • [Title] Sacrococygeal teratoma with sarcomatous differentiation in a child.
  • Most of the extragonadal teratomas are located in the sacrococygeal region.
  • Teratoma with malignant sarcomatous differentiation is a rare form of germ cell tumor.
  • The authors describe a 5-year-old-girl with sacrococygeal teratoma in which sarcomatous elements were observed.
  • The patient was treated with complete surgical excision and adjuvant chemotherapy according to sarcoma protocols.
  • [MeSH-major] Sacrococcygeal Region. Sarcoma / pathology. Soft Tissue Neoplasms / pathology. Teratoma / pathology
  • [MeSH-minor] Actins / analysis. Child, Preschool. Combined Modality Therapy. Dactinomycin / therapeutic use. Female. Humans. Magnetic Resonance Imaging. Vimentin / analysis. Vincristine / therapeutic use

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  • (PMID = 18484480.001).
  • [ISSN] 1521-0669
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Vimentin; 1CC1JFE158 / Dactinomycin; 5J49Q6B70F / Vincristine
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29. Chen YH, Chang CH, Chen KC, Diau GY, Loh IW, Chu CC: Malignant transformation of a well-organized sacrococcygeal fetiform teratoma in a newborn male. J Formos Med Assoc; 2007 May;106(5):400-2
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  • [Title] Malignant transformation of a well-organized sacrococcygeal fetiform teratoma in a newborn male.
  • We report herein a case of a male newborn with a sacrococcygeal fetiform teratoma (FT).
  • The baby presented with a large coccygeal teratoma.
  • The preoperative diagnosis of FT was made by plain radiography, ultrasonography and magnetic resonance imaging.
  • Postoperative follow-up was uneventful until the teratoma recurred 11 months later as a malignancy.
  • After undergoing a second operative procedure accompanied by chemotherapy, he has been doing well for 18 months.

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  • (PMID = 17561476.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] 0 / alpha-Fetoproteins; 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
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30. Peterson EC, Alden TD, Patterson K, Lipson A, Friedman D, Garcia J, Avellino AM: Epidural metastases from endodermal sinus tumor arising from benign sacral teratoma. Case report and review of the literature. J Neurosurg; 2007 Oct;107(4 Suppl):303-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epidural metastases from endodermal sinus tumor arising from benign sacral teratoma. Case report and review of the literature.
  • The authors describe a case of a mature sacrococcygeal teratoma in a 4-day-old female patient that recurred after 22 months as an EST with epidural metastases.
  • Pathological testing of samples of both the recurrent pelvic and the extradural spinal tumors led to a diagnosis of EST.
  • The patient underwent four cycles of chemotherapy with normalization of her AFP level to 13 ng/ml.
  • The patient underwent a second course of chemotherapy followed by two tandem courses of high-dose chemotherapy with autologous stem-cell rescue.
  • Since completing this therapy the patient has been clinically stable with an AFP level of 1.3 ng/ml for 14 months.
  • To the authors' knowledge, this is the first case of a mature sacrococcygeal tumor that recurred as an EST and caused spinal canal compromise.
  • [MeSH-major] Endodermal Sinus Tumor / secondary. Neoplasm Recurrence, Local / pathology. Pelvic Neoplasms / pathology. Spinal Neoplasms / secondary. Teratoma / pathology
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Coccyx. Epidural Space. Female. Humans. Infant, Newborn. Magnetic Resonance Imaging. Neurosurgical Procedures. Sacrum. alpha-Fetoproteins / metabolism

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  • (PMID = 17941495.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / alpha-Fetoproteins
  • [Number-of-references] 14
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31. Albert A, Cruz O, Montaner A, Vela A, Badosa J, Castañón M, Morales L: [Congenital solid tumors. A thirteen-year review]. Cir Pediatr; 2004 Jul;17(3):133-6
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  • This is an interesting group of tumors because their type, relative incidence, natural history and response to treatment differ from those seen in older children.
  • Treatment was surgical resection alone in 17 cases (68%) and surgery + chemotherapy in 8 (32%) (5 neuroblastomas, one CNS tumor, one Wilms tumor and one presacral teratoma who developed a yolk sac tumor); 3 patients died (11%): one at surgery, one of tumoural airway obstruction at birth and one with craniopharyngioma.
  • Among the 14 tumors that were initially not malignant, two can be locally agressive, one was an immature teratoma, the giant nevus with hamartoma developed in situ melanoma, the other nevus had meningeal melanosis with hydrocephalus, and one mature presacral teratoma developed a yolk sac tumor.
  • CONCLUSIONS: Diagnosis of congenital tumors is performed earlier in recent years due to the wide use of prenatal ultrasound.
  • Complete surgical excision is the treatment of choice, most cases not need adjuvant chemotherapy.
  • We ought to pass this message on to our colleagues in prenatal diagnosis, so parents get reliable information.
  • [MeSH-major] Central Nervous System Neoplasms / congenital. Kidney Neoplasms / congenital. Liver Neoplasms / congenital. Neuroblastoma / congenital. Skin Neoplasms / congenital. Soft Tissue Neoplasms / congenital. Teratoma / congenital. Wilms Tumor / congenital
  • [MeSH-minor] Female. Follow-Up Studies. Humans. Infant, Newborn. Male. Neoplasm Recurrence, Local. Postoperative Complications. Pregnancy. Prenatal Diagnosis. Time Factors


32. Jung CK, Lee YS, Jung ES, Kang CS, Kim BK: Oligodendroglioma arising in a sacrococcygeal immature teratoma. J Korean Med Sci; 2002 Jun;17(3):426-8
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  • [Title] Oligodendroglioma arising in a sacrococcygeal immature teratoma.
  • Tumors of neuroepithelial origin are extremely rare in teratoma and tend to be derived from glial or primitive neuroectodermal cells.
  • We describe a case of 2- month-old baby girl with an oligodendroglioma arising in an immature teratoma of the sacrococcygeal region.
  • Because immature teratoma was grade II, the patient received adjuvant chemotherapy.
  • [MeSH-major] Oligodendroglioma / pathology. Sacrococcygeal Region / pathology. Spinal Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 12068154.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3054871
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