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Items 1 to 36 of about 36
1. Chamberlain MC: Salvage chemotherapy for recurrent spinal cord ependymona. Cancer; 2002 Sep 1;95(5):997-1002
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  • [Title] Salvage chemotherapy for recurrent spinal cord ependymona.
  • BACKGROUND: Ependymomas are reported to constitute 4% of all primary central nervous system (CNS) malignancies in adults, 30% of which occur in the spinal cord.
  • A prospective Phase II study to determine toxicity and response to chronic oral etoposide in patients with recurrent low-grade intramedullary spinal cord ependymoma (SCE) was conducted.
  • METHODS: Ten patients (6 males and 4 females with a median age of 30 years) with recurrent SCE were treated with oral etoposide (50mg/m(2)/day given daily for 21 days followed by a 14-day break and then repeated constituted a cycle of therapy).
  • All patients had failed surgery and radiotherapy and four patients had failed one prior chemotherapy.
  • Contrast-enhanced magnetic resonance imaging of the spine was performed every 8 weeks after a cycle of etoposide and before the next cycle of chemotherapy was initiated.
  • RESULTS: Treatment-related complications included alopecia in 9 patients, nonbloody diarrhea in 6 patients, a baseline weight loss of > 10% in 5 patients, Grade (according to the National Cancer Institute Common Toxicity Scale) 3-4 neutropenia in 3 patients, Grade 3-4 thrombocytopenia in 3 patients, and Grade 3-4 anemia in 2 patients.
  • There were no treatment-related deaths reported.
  • CONCLUSIONS: Chronic oral etoposide appears to be well tolerated, has modest toxicity, and had apparent activity in the small cohort of adults in the current study with surgically and medically refractory, recurrent, intradural intramedullary SCE.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / pharmacology. Ependymoma / drug therapy. Etoposide / pharmacology. Neoplasm Recurrence, Local / drug therapy. Spinal Cord Neoplasms / drug therapy
  • [MeSH-minor] Administration, Oral. Adult. Alopecia / chemically induced. Disease-Free Survival. Drug Administration Schedule. Female. Humans. Male. Middle Aged. Salvage Therapy. Thrombocytopenia / chemically induced. Treatment Outcome. Weight Loss

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  • [Copyright] Copyright 2002 American Cancer Society.
  • (PMID = 12209682.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Clinical Trial; Clinical Trial, Phase II; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 6PLQ3CP4P3 / Etoposide
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2. Kinoshita Y, Akatsuka K, Ohtake M, Kamitani H, Watanabe T: Primary intramedullary spinal cord germinoma. Neurol Med Chir (Tokyo); 2010;50(7):592-4
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  • [Title] Primary intramedullary spinal cord germinoma.
  • A 21-year-old woman presented with an intramedullary spinal cord germinoma and a history of gait disturbance and elimination disorder.
  • After partial reduction of the intramedullary mass, histological findings revealed that the tumor was typical germinoma.
  • Combined chemotherapy (carboplatin and etoposide) and whole spine radiation were performed.
  • Cisplatin and etoposide chemotherapy combined with radiotherapy is recommended for primary spinal germinoma, and is effective for inhibition of both tumor dissemination and recurrence.
  • [MeSH-major] Germinoma / diagnosis. Germinoma / surgery. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / surgery. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Humans. Lumbar Vertebrae. Radiotherapy, Adjuvant. Spinal Cord / pathology. Spinal Cord / surgery. Thoracic Vertebrae. Young Adult

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  • (PMID = 20671389.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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3. Yamagata T, Takami T, Tsuyuguchi N, Goto T, Wakasa K, Ohata K: Primary intramedullary spinal cord germinoma: diagnostic challenge and treatment strategy. Neurol Med Chir (Tokyo); 2009 Mar;49(3):128-33
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  • [Title] Primary intramedullary spinal cord germinoma: diagnostic challenge and treatment strategy.
  • Two patients presented with primary intramedullary spinal cord germinoma (PISCG).
  • Based on the histological diagnosis, both patients were treated successfully by combination of chemotherapy and radiotherapy.
  • These cases illustrate the unexpected occurrence of PISCG and treatment strategy.
  • [MeSH-major] Germinoma / diagnosis. Spinal Cord / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Paraplegia / etiology. Radiotherapy / methods. Sensation Disorders / etiology. Treatment Outcome. Urinary Incontinence / etiology. Young Adult

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  • (PMID = 19318740.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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4. Taricco MA, Guirado VM, Fontes RB, Plese JP: Surgical treatment of primary intramedullary spinal cord tumors in adult patients. Arq Neuropsiquiatr; 2008 Mar;66(1):59-63
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  • [Title] Surgical treatment of primary intramedullary spinal cord tumors in adult patients.
  • BACKGROUND: Primary spinal cord intramedullary tumors are rare and present with insidious symptoms.
  • Previous treatment protocols emphasized biopsy and radiation/chemotherapy but more aggressive protocols have emerged.
  • METHOD: Forty-eight patients were diagnosed with primary intramedullary tumors.
  • The cervical cord was involved in 27% and thoracic in 42% of patients.
  • [MeSH-major] Cervical Vertebrae. Spinal Cord Neoplasms / surgery. Thoracic Vertebrae
  • [MeSH-minor] Adult. Female. Humans. Male. Neoplasm Staging. Prognosis. Treatment Outcome

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  • (PMID = 18392416.001).
  • [ISSN] 0004-282X
  • [Journal-full-title] Arquivos de neuro-psiquiatria
  • [ISO-abbreviation] Arq Neuropsiquiatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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5. Otero-Rodríguez A, Hinojosa J, Esparza J, Muñoz MJ, Iglesias S, Rodríguez-Gil Y, Ricoy JR: Purely intramedullary spinal cord primitive neuroectodermal tumor: case report and review of the literature. Neurocirugia (Astur); 2009 Aug;20(4):381-6; discussion 386-7
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  • [Title] Purely intramedullary spinal cord primitive neuroectodermal tumor: case report and review of the literature.
  • INTRODUCTION: Primitive neuroectodermal tumors (PNETs) are malign neoplasms of the central nervous system which mainly locate in cerebellum (medulloblastoma).
  • Primary intraspinal PNETs are rare.
  • Within this group, we have found ten cases of purely intramedullary PNETs (IPNETs).
  • In this report, we describe a new IPNET case and review the literature about these infrequent intramedullary tumors.
  • Spine magnetic resonance imaging revealed an intramedullary expansive lesion from T3 to T10.
  • Subsequent chemotherapy was recommended.
  • Outcome is dismal: most patients die within two years in spite of surgical resection followed by radiotherapy and chemotherapy.
  • [MeSH-major] Neuroectodermal Tumors, Primitive / pathology. Spinal Cord Neoplasms / pathology. Thoracic Vertebrae
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Cisplatin / administration & dosage. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Disease Progression. Etoposide / administration & dosage. Humans. Infant. Magnetic Resonance Imaging. Male. Methotrexate / administration & dosage. Paraparesis / etiology. Prognosis

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  • (PMID = 19688140.001).
  • [ISSN] 1130-1473
  • [Journal-full-title] Neurocirugía (Asturias, Spain)
  • [ISO-abbreviation] Neurocirugia (Astur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; 8N3DW7272P / Cyclophosphamide; BG3F62OND5 / Carboplatin; Q20Q21Q62J / Cisplatin; YL5FZ2Y5U1 / Methotrexate
  • [Number-of-references] 19
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6. Fujimoto N, Hiraki A, Ueoka H, Kiura K, Bessho A, Takata I, Hiramatsu Y, Ikeda K, Harada M: Intramedullary spinal cord recurrence after high-dose chemotherapy and autologous peripheral blood progenitor cell transplantation for limited-disease small cell lung cancer. Lung Cancer; 2000 Nov;30(2):145-8
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  • [Title] Intramedullary spinal cord recurrence after high-dose chemotherapy and autologous peripheral blood progenitor cell transplantation for limited-disease small cell lung cancer.
  • Intramedullary spinal cord metastasis is very rare in small-cell lung cancer (SCLC), and develops in only 2% of neurological disorders associated with SCLC according to previous reports.
  • We describe here a patient with SCLC who developed intramedullary spinal cord recurrence after high-dose chemotherapy (HDCT) followed by autologous blood progenitor cell transplantation (ABPCT).
  • A 59-year-old Japanese male was referred to us for diagnosis and treatment of an abnormal shadow on a chest radiograph.
  • Magnetic resonance imaging (MRI) of the spinal cord disclosed an intramedullary tumor exhibiting an enhancement effect with Gd-DTPA at the 11-12th level of the thoracic vertebra.
  • Immediately, radiotherapy to the spinal cord metastasis was given at a dose of 30 Gy, and his neurological disorders were completely resolved.
  • At this time of reporting, he is doing well without recurrence.
  • This case indicates that intramedullary spinal cord is one of the recurrence sites implicated after HDCT and PCI in LD-SCLC.
  • [MeSH-major] Carcinoma, Small Cell / secondary. Lung Neoplasms / pathology. Neoplasms, Second Primary. Spinal Cord Neoplasms / secondary
  • [MeSH-minor] Combined Modality Therapy. Drug Therapy. Hematopoietic Stem Cell Transplantation. Humans. Male. Medulla Oblongata. Middle Aged. Transplantation, Autologous

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  • (PMID = 11086208.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] IRELAND
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7. Harrop JS, Ganju A, Groff M, Bilsky M: Primary intramedullary tumors of the spinal cord. Spine (Phila Pa 1976); 2009 Oct 15;34(22 Suppl):S69-77
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  • [Title] Primary intramedullary tumors of the spinal cord.
  • OBJECTIVE: To define optimal clinical care for primary intramedullary spinal cord tumors using a systematic review with expert opinion.
  • METHODS: Focused questions on the treatment of primary intramedullary spinal cord tumors were refined by a panel of spine oncology surgeons, medical and radiation oncologist.
  • These treatment recommendations were then rated as either strong or weak based on the quality of evidence and clinical expertise.
  • The subsequent search resulted in a return of: "spinal cord tumor" (5053), "ependymoma" (580), "astrocytoma" (420), and "glioma" (235) articles.
  • Seventeen articles referenced timing of surgical intervention and symptomatology for intramedullary spinal cord tumors.
  • One hundred fifty-eight chemotherapy and 183 radiation therapy articles for intramedullary spinal cord tumors were reviewed.
  • Adjuvant therapy is an option for high grade astrocytomas (WHO grades 3-4).
  • [MeSH-major] Glioma / radiotherapy. Glioma / surgery. Spinal Cord Neoplasms / radiotherapy. Spinal Cord Neoplasms / surgery
  • [MeSH-minor] Humans. Radiotherapy, Adjuvant. Severity of Illness Index. Treatment Outcome

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  • (PMID = 19829279.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 75
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8. Cormio G, Di Vagno G, Di Fazio F, Loverro G, Selvaggi L: Intramedullary spinal cord metastasis from ovarian carcinoma. Gynecol Oncol; 2001 Jun;81(3):506-8
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  • [Title] Intramedullary spinal cord metastasis from ovarian carcinoma.
  • BACKGROUND: Intramedullary spinal cord involvement by ovarian carcinoma is extremely rare.
  • CASE: A patient with stage IV serous cystadenocarcinoma of the ovary presented with neurologic complaints 16 months after primary treatment.
  • Magnetic resonance imaging demonstrated a metastatic lesion in the intramedullary area of the spinal cord.
  • Following chemotherapy she was given radiotherapy on the spinal cord, but died 10 months later for disseminated abdominal disease, without neurologic symptoms.
  • CONCLUSION: Spinal cord involvement is unusual in ovarian carcinoma; multidisciplinary treatment, including chemotherapy and radiotherapy, may offer good palliation of the symptomatology.
  • [MeSH-major] Cystadenocarcinoma, Serous / secondary. Ovarian Neoplasms / pathology. Spinal Cord Neoplasms / secondary
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Carboplatin / therapeutic use. Female. Humans. Middle Aged

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  • [Copyright] Copyright 2001 Academic Press.
  • (PMID = 11371147.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; BG3F62OND5 / Carboplatin
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9. Aryan HE, Farin A, Nakaji P, Imbesi SG, Abshire BB: Intramedullary spinal cord metastasis of lung adenocarcinoma presenting as Brown-Sequard syndrome. Surg Neurol; 2004 Jan;61(1):72-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramedullary spinal cord metastasis of lung adenocarcinoma presenting as Brown-Sequard syndrome.
  • BACKGROUND: It is extremely rare for cancer to present first as an intramedullary spinal cord metastasis.
  • Furthermore, because it is unlikely for spinal cord neoplasm to present acutely, an acute presentation may signify metastatic disease and should be considered in the initial differential diagnosis.
  • METHODS: The authors present a case of a 59-year-old man presenting with Brown-Sequard syndrome and in whom metastatic lung adenocarcinoma to the spinal cord was subsequently discovered.
  • Review of the literature reveals this case to be one of only a very few where intramedullary tumor was the first manifestation of metastatic disease.
  • RESULTS: The mainstay of treatment for intramedullary spinal metastases remains steroids, radiation, and chemotherapy, though no well-designed study compares these modalities by long-term survival and functional results.
  • This patient underwent local radiation and systemic chemotherapy following surgical resection.
  • CONCLUSIONS: This patient had no preoperative signs suggesting disease in other organs, making the diagnosis of lung adenocarcinoma metastatic to the intramedullary cord surprising, especially given the extremely rare incidence of spinal intramedullary metastatic disease.
  • However, the patient had an acute presentation, uncommon for primary neoplasm, which may be an indication of metastatic disease.
  • [MeSH-major] Adenocarcinoma / secondary. Brown-Sequard Syndrome / diagnosis. Lung Neoplasms / pathology. Spinal Cord Neoplasms / secondary

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  • (PMID = 14706385.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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10. Kodama M, Kawaguchi H, Komoto Y, Takemura M: Coexistent intramedullary spinal cord and choroidal metastases in ovarian cancer. J Obstet Gynaecol Res; 2010 Feb;36(1):199-203
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  • [Title] Coexistent intramedullary spinal cord and choroidal metastases in ovarian cancer.
  • Involvement of intramedullary spinal cord and the choroid by ovarian cancer is rare, and coexistence of metastases at these sites is extremely rare and has never been reported.
  • This condition rapidly progresses to a neurological emergency; however, an efficient standard treatment method is not available for this rare condition.
  • She presented with blindness and other neurologic complaints during the course of treatment for a recurrence at 50 months after the primary surgical treatment for the tumor.
  • Magnetic resonance imaging (MRI) revealed intramedullary spinal cord metastasis and choroidal metastasis, coexisting with multiple brain metastases and intra-abdominal lesions.
  • Neurological emergency was prevented by administering whole-brain irradiation therapy followed by systemic chemotherapy.
  • Early diagnosis and multidisciplinary treatment, including radiotherapy and chemotherapy, may offer good palliation for such unusual metastases of ovarian cancer.
  • [MeSH-major] Brain Neoplasms / secondary. Choroid Neoplasms / secondary. Cystadenocarcinoma, Serous / secondary. Neoplasm Recurrence, Local. Ovarian Neoplasms / pathology. Spinal Cord Neoplasms / secondary
  • [MeSH-minor] Abdominal Neoplasms / secondary. Abdominal Neoplasms / therapy. Aged, 80 and over. Combined Modality Therapy. Female. Humans. Hysterectomy. Ovariectomy

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  • (PMID = 20178552.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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11. Takahashi M, Koyama H, Matsubara T, Murata H, Miura K, Nagano A: Mixed germinoma and choriocarcinoma in the intramedullary spinal cord: case report and review of the literature. J Neurooncol; 2006 Jan;76(1):71-5
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  • [Title] Mixed germinoma and choriocarcinoma in the intramedullary spinal cord: case report and review of the literature.
  • Primary germinomas in the spinal cord are very rare with only 15 cases published previously.
  • The pathological diagnosis was mixed germinoma and choriocarcinoma of the intramedullary spinal cord.
  • She received craninospinal irradiation and three courses of chemotherapy and is currently asymptomatic with no evidence of recurrence and metastasis 22 months after surgery.
  • To our knowledge, this is the first case report of a patient with a primary mixed germinoma and choriocarcinoma of the intramedullary spinal cord.
  • The previous 15 cases of primary spinal cord germinoma have been reviewed for comparison.
  • [MeSH-major] Choriocarcinoma / drug therapy. Choriocarcinoma / radiotherapy. Germinoma / drug therapy. Germinoma / radiotherapy. Spinal Cord Neoplasms / drug therapy. Spinal Cord Neoplasms / radiotherapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Female. Humans. Muscle Weakness / etiology. Pain / etiology. Treatment Outcome. Urinary Incontinence / etiology

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  • [Cites] J Neurooncol. 2000 May;47(3):293-307 [11016745.001]
  • [Cites] Cancer. 1985 Jun 15;55(12 ):2845-9 [3857960.001]
  • [Cites] Surg Neurol. 1991 Feb;35(2):122-6 [1990479.001]
  • [Cites] J Neurooncol. 2003 May;63(1):69-73 [12814257.001]
  • [Cites] J Neurooncol. 2002 Feb;56(3):247-50 [12061731.001]
  • [Cites] Chin Med J (Engl). 2002 Sep;115(9):1418-9 [12411127.001]
  • [Cites] Neurol Med Chir (Tokyo). 1991 Nov;31(11):729-31 [1723162.001]
  • [Cites] Radiology. 2002 May;223(2):379-83 [11997540.001]
  • [Cites] J Clin Oncol. 2001 Feb 1;19(3):911-5 [11157045.001]
  • [Cites] Acta Neuropathol. 1995;90(6):657-9 [8615089.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Jun 1;56(2):511-8 [12738328.001]
  • [Cites] Spine (Phila Pa 1976). 1995 Nov 1;20(21):2338-40 [8553123.001]
  • [Cites] Neurosurgery. 1996 Jan;38(1):187-90; discussion 190-1 [8747968.001]
  • [Cites] Pathol Int. 1999 Jul;49(7):633-7 [10504524.001]
  • [Cites] J Neurosurg. 1996 Jun;84(6):1060-1 [8847573.001]
  • [Cites] Rofo. 1993 Aug;159(2):203-4 [8353271.001]
  • (PMID = 16132500.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Peltier J, Cretu I, Fichten A, Toussaint P, Desenclos C, Le Gars D: [Primary intramedullary lymphoma. Case report]. Neurochirurgie; 2007 Nov;53(5):375-8
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  • [Title] [Primary intramedullary lymphoma. Case report].
  • A 66-year-old female presented primary intramedullary spinal cord lymphoma.
  • This patient was referred for lower limbs weakness, which had developed six weeks earlier and right C5 radiculalgia.
  • The patient was given chemotherapy and craniospinal adjuvant radiotherapy (30 Grays).
  • The clinical, radiological and therapeutic features are discussed.
  • [MeSH-major] Lymphoma / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Aged. Biopsy. Combined Modality Therapy. Female. Humans. Immunohistochemistry. Laminectomy. Magnetic Resonance Imaging. Spinal Cord / pathology. Vimentin / metabolism

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  • (PMID = 17689569.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Vimentin
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13. Sasaki T, Amano T, Takao M, Shibata M, Shigematsu N, Fukuuchi Y: A case of intramedullary spinal cord tumor producing human chorionic gonadotropin. J Neurooncol; 2002 Feb;56(3):247-50

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of intramedullary spinal cord tumor producing human chorionic gonadotropin.
  • We experienced a case of a persistent trophoblastic disease associated with gradually progressive Brown-Sequard syndrome, which was found to be due to a primary intramedullary spinal cord germinoma with syncytiotrophoblastic giant cells (STGC).
  • We performed both chemotherapy and radiotherapy on separate occasions.
  • Although the chemotherapy appeared to be ineffective, radiotherapy resulted in the disappearance of spinal cord lesions for four years.
  • We reported a case of intramedullary spinal cord germinoma with STGC for which radiotherapy was a better therapeutic modality.
  • [MeSH-major] Brain Stem Neoplasms / secretion. Chorionic Gonadotropin / secretion. Spinal Cord Neoplasms / secretion

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  • [Cites] J Neurol. 1979 Jan 30;220(1):31-41 [84065.001]
  • [Cites] Cancer. 1985 Jun 15;55(12 ):2845-9 [3857960.001]
  • [Cites] Surg Neurol. 1991 Feb;35(2):122-6 [1990479.001]
  • [Cites] Surg Neurol. 1994 Feb;41(2):106-11 [8115946.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1997 Feb 1;37(3):505-10 [9112445.001]
  • [Cites] Curr Opin Neurol. 1996 Dec;9(6):419-23 [9007398.001]
  • [Cites] Obstet Gynecol Surv. 1984 May;39(5):247-51 [6717864.001]
  • [Cites] Acta Neuropathol. 1995;90(6):657-9 [8615089.001]
  • [Cites] J Neurooncol. 1992 Jul;13(3):247-56 [1517802.001]
  • [Cites] Spine (Phila Pa 1976). 1995 Nov 1;20(21):2338-40 [8553123.001]
  • [Cites] Cancer Treat Rev. 2000 Aug;26(4):233-42 [10913379.001]
  • [Cites] Neurosurgery. 1996 Jan;38(1):187-90; discussion 190-1 [8747968.001]
  • [Cites] J Neurosurg. 1996 Jun;84(6):1060-1 [8847573.001]
  • [Cites] Rofo. 1993 Aug;159(2):203-4 [8353271.001]
  • (PMID = 12061731.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin
  • [Number-of-references] 15
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14. Aoyama T, Hida K, Ishii N, Seki T, Ikeda J, Iwasaki Y: Intramedullary spinal cord germinoma--2 case reports. Surg Neurol; 2007 Feb;67(2):177-83; discussion 183
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramedullary spinal cord germinoma--2 case reports.
  • BACKGROUND: Primary intramedullary spinal cord germinoma is very rare.
  • We encountered 2 patients with primary intramedullary spinal cord germinoma.
  • We describe herein our comprehensive management system for CNS germinoma, including intramedullary spinal cord germinoma, along with a review of the literature.
  • This is the first report to describe successful application of ICE chemotherapy for intramedullary germinoma.
  • Magnetic resonance imaging demonstrated marked cord swelling between T9 and T12, with slight enhancement in the spinal cord.
  • Successful treatment with ICE chemotherapy and radiotherapy was implemented, with no evidence of recurrence apparent at 48 months postoperatively.
  • Magnetic resonance imaging demonstrated cord swelling between T8 and T10, with slight Gd-DTPA enhancement.
  • Because the lesion did not respond to steroid pulse therapy, spinal cord tumor was suspected and biopsy was performed.
  • Pathologic examination verified primary germinoma of the spine.
  • Successful treatment with ICE chemotherapy and radiotherapy was implemented with no exacerbation of neurologic deficits.
  • CONCLUSION: Correct diagnosis of very rare primary intramedullary spinal cord germinoma is important, because these patients can be treated successfully using chemo- and radiotherapy without neurologic deterioration.
  • [MeSH-major] Germinoma / diagnosis. Germinoma / therapy. Spinal Cord / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Chorionic Gonadotropin, beta Subunit, Human / analysis. Chorionic Gonadotropin, beta Subunit, Human / metabolism. Female. Humans. Magnetic Resonance Imaging. Neurosurgical Procedures. Paraparesis / etiology. Radiotherapy. Treatment Outcome. Urination Disorders / etiology

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  • (PMID = 17254883.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin, beta Subunit, Human
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15. Grimm S, Chamberlain MC: Adult primary spinal cord tumors. Expert Rev Neurother; 2009 Oct;9(10):1487-95

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adult primary spinal cord tumors.
  • Primary spinal cord tumors represent 2-4% of all neoplasms of the CNS.
  • Primary spinal cord tumors are anatomically separable into two broad categories: intradural intramedullary and intradural extramedullary.
  • Intramedullary tumors are comprised predominantly of gliomas (infiltrative astrocytomas and ependymomas).
  • Resective surgery can usually be accomplished with spinal ependymomas owing to separation of tumor from spinal cord and, when complete, require no further therapy.
  • By contrast, spinal cord gliomas infiltrate the myelon and, consequently, surgery is nearly always incomplete.
  • Chemotherapy is administered for recurrent primary spinal cord tumors without other options, that is, reoperation or re-irradiation.
  • Problematic, however, is the lack of clinical trials in general for these CNS tumors and for spinal cord tumors in particular.
  • Consequently, treatment is similar to that for intracranial tumors with a similar histology.
  • Early recognition of the signs and symptoms of primary spinal cord tumors allows for early treatment, potentially minimizes neurologic morbidity and improves outcome.
  • Primary treatment is surgery in essentially all spinal cord tumors, and predictors of outcome include preoperative functional status, histological grade of tumor and extent of surgical resection.
  • [MeSH-major] Spinal Cord Neoplasms / classification. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Humans. Neurosurgical Procedures. Young Adult

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  • (PMID = 19831838.001).
  • [ISSN] 1744-8360
  • [Journal-full-title] Expert review of neurotherapeutics
  • [ISO-abbreviation] Expert Rev Neurother
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 82
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16. Bekar A, Cordan T, Evrensel T, Tolunay S: A case of primary spinal intramedullary lymphoma. Surg Neurol; 2001 May;55(5):261-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of primary spinal intramedullary lymphoma.
  • The diagnostic work-up revealed an intramedullary mass at spinal level C2-4.
  • The patient was treated with corticosteroids, chemotherapy, and adjuvant radiotherapy.
  • The residual tumor tissue had completely disappeared by 6 months of follow-up; however, the patient presented with intraventricular metastasis at 11 months postsurgery.
  • [MeSH-major] Cerebral Ventricle Neoplasms / secondary. Lymphoma, B-Cell / diagnosis. Lymphoma, Non-Hodgkin / diagnosis. Spinal Cord Neoplasms / diagnosis
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Diagnosis, Differential. Humans. Laminectomy. Magnetic Resonance Imaging. Male. Paresis / etiology. Radiotherapy, Adjuvant

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  • (PMID = 11516461.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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17. Mut M, Schiff D, Shaffrey ME: Metastasis to nervous system: spinal epidural and intramedullary metastases. J Neurooncol; 2005 Oct;75(1):43-56
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastasis to nervous system: spinal epidural and intramedullary metastases.
  • Spinal cord epidural metastasis (SEM) is a common complication of systemic cancer with an increasing incidence.
  • Pathophysiologically, vascular insufficiency is more important than direct spinal cord compression.
  • Radiotherapy has an important role, particularly in treatment of radiosensitive tumors and in patients who are not candidates for surgery.
  • Novel approaches such as stereotactic radiosurgery are promising; however, response to chemotherapy depends on inherent properties of primary tumor.
  • Intramedullary metastasis is rare but should be considered in patients with systemic malignancy and asymmetrical presentation of myelopathic symptoms.
  • The prognosis is usually poor and preferred modality of treatment is radiotherapy.
  • [MeSH-major] Epidural Neoplasms / secondary. Spinal Cord Neoplasms / secondary

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  • [Cites] J Neurol Neurosurg Psychiatry. 1990 Nov;53(11):1001-3 [2283511.001]
  • [Cites] N Engl J Med. 1992 Aug 27;327(9):614-9 [1296600.001]
  • [Cites] Cancer. 1991 Mar 1;67(5):1311-7 [1991293.001]
  • [Cites] J Neurol. 1979 Jan 30;220(1):31-41 [84065.001]
  • [Cites] Cancer. 2003 Apr 15;97(8):2013-8 [12673732.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Oct 1;54(2):505-13 [12243829.001]
  • [Cites] Clin Orthop Relat Res. 1988 Aug;(233):177-97 [3402124.001]
  • [Cites] Neurology. 1977 May;27(5):422-9 [558545.001]
  • [Cites] Neurology. 1996 Jun;46(6):1543-7 [8649545.001]
  • [Cites] Acta Neurochir (Wien). 1997;139(2):105-11 [9088367.001]
  • [Cites] Acta Neurochir (Wien). 1990;103(3-4):131-8 [2399840.001]
  • [Cites] Cancer. 1985 Nov 1;56(9):2305-14 [4052974.001]
  • [Cites] Acta Orthop Scand. 1995 Apr;66(2):143-6 [7740944.001]
  • [Cites] Int Urol Nephrol. 1991;23 (4):351-6 [1938231.001]
  • [Cites] Cancer. 1997 Oct 15;80(8 Suppl):1595-607 [9362427.001]
  • [Cites] Cancer. 1989 Jun 1;63(11):2234-41 [2524249.001]
  • [Cites] Eur Spine J. 1996;5(6):407-11 [8988384.001]
  • [Cites] Ala Med. 1990 Jul-Aug;60(1-2):10-5 [2239623.001]
  • [Cites] Eur J Cancer. 1994;30A(3):396-8 [8204366.001]
  • [Cites] J Neurosurg. 1996 Sep;85(3):438-46 [8751630.001]
  • [Cites] Acta Neurochir (Wien). 1990;107(1-2):37-43 [2096606.001]
  • [Cites] Stereotact Funct Neurosurg. 1996;66(1-3):1-9 [8938925.001]
  • [Cites] Neurology. 1992 Nov;42(11):2193-5 [1436534.001]
  • [Cites] Spine (Phila Pa 1976). 2000 Sep 1;25(17):2240-9,discussion 250 [10973409.001]
  • [Cites] Spinal Cord. 1997 Jul;35(7):429-36 [9232747.001]
  • [Cites] Cancer. 1990 Jan 1;65(1):98-106 [2293874.001]
  • [Cites] Neurology. 1989 Sep;39(9):1255-7 [2771077.001]
  • [Cites] Q J Med. 1986 Nov;61(235):1003-20 [3659245.001]
  • [Cites] J Pain Symptom Manage. 2000 Apr;19(4):257-64 [10799792.001]
  • [Cites] Neurosurgery. 1988 Jun;22(6 Pt 1):1005-7 [3419560.001]
  • [Cites] Acta Neurol Scand. 1996 Oct;94(4):269-75 [8937539.001]
  • [Cites] Spine (Phila Pa 1976). 1999 Sep 15;24(18):1943-51 [10515021.001]
  • [Cites] Spine (Phila Pa 1976). 1990 Nov;15(11):1110-3 [1702559.001]
  • [Cites] Spine (Phila Pa 1976). 1997 Oct 1;22(19):2293-8 [9346151.001]
  • [Cites] Lancet. 1968 Oct 26;2(7574):912 [4176160.001]
  • [Cites] Comput Med Imaging Graph. 1996 May-Jun;20(3):159-62 [8930468.001]
  • [Cites] Neuroradiology. 1993;35(4):288-92 [8492898.001]
  • [Cites] Am J Phys Med Rehabil. 2003 Sep;82(9):665-8 [12960907.001]
  • [Cites] BMJ. 1998 Jul 4;317(7150):18-21 [9651261.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1992 Dec;55(12):1188-93 [1479399.001]
  • [Cites] J Clin Oncol. 1995 Sep;13(9):2330-5 [7666091.001]
  • [Cites] Ann Neurol. 1995 May;37(5):583-9 [7755352.001]
  • [Cites] Am J Clin Oncol. 2000 Feb;23(1):89-93 [10683087.001]
  • [Cites] Acta Orthop Scand. 1993 Feb;64(1):3-8 [8451941.001]
  • [Cites] Ann Neurol. 1978 Jan;3(1):40-51 [655653.001]
  • [Cites] J Neurosurg. 1985 Feb;62(2):227-33 [3968561.001]
  • [Cites] Acta Neurochir (Wien). 2003 Oct;145(10):873-80; discussion 880-1 [14577009.001]
  • [Cites] Surg Neurol. 1996 Oct;46(4):329-37; discussion 337-8 [8876713.001]
  • [Cites] Cancer. 1982 Sep 1;50(5):893-9 [6178497.001]
  • [Cites] J Neurooncol. 1989 Jul;7(2):129-36 [2778489.001]
  • [Cites] Neuro Oncol. 1999 Apr;1(2):120-3 [11550307.001]
  • [Cites] Eur Spine J. 1998;7(6):438-44 [9883951.001]
  • [Cites] J Neurosurg. 1977 Sep;47(3):380-90 [894341.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Nov 1;57(3):605-13 [14529763.001]
  • [Cites] Ann Neurol. 1986 Dec;20(6):696-702 [2949691.001]
  • [Cites] Spine (Phila Pa 1976). 1990 Jan;15(1):1-4 [2326692.001]
  • [Cites] Neurology. 1996 Oct;47(4):906-12 [8857717.001]
  • [Cites] Paraplegia. 1969 Nov;7(3):179-92 [5360915.001]
  • [Cites] Neurology. 1990 Aug;40(8):1234-6 [2381531.001]
  • [Cites] Cancer. 1995 Oct 15;76(8):1453-9 [8620423.001]
  • [Cites] Am J Clin Oncol. 1996 Apr;19(2):179-83 [8610645.001]
  • [Cites] Arch Phys Med Rehabil. 1996 Sep;77(9):892-5 [8822680.001]
  • [Cites] Cancer. 2003 Jan 15;97(2):476-84 [12518372.001]
  • [Cites] Am J Med. 1988 Mar;84(3 Pt 1):555-8 [3279772.001]
  • [Cites] Cancer. 1998 Oct 15;83(8):1593-601 [9781953.001]
  • [Cites] Spinal Cord. 2003 Apr;41(4):205-10 [12669084.001]
  • [Cites] AJR Am J Roentgenol. 1992 Jun;158(6):1275-9 [1590123.001]
  • [Cites] Med Pediatr Oncol. 1983;11(5):347-51 [6633426.001]
  • [Cites] Br J Neurosurg. 1996 Feb;10(1):27-33 [8672255.001]
  • [Cites] Neurology. 2002 May 14;58(9):1360-6 [12011281.001]
  • [Cites] Spine (Phila Pa 1976). 2001 Feb 1;26(3):298-306 [11224867.001]
  • [Cites] J Neurosurg. 1989 Jun;70(6):920-5 [2715820.001]
  • [Cites] Eur J Cancer Clin Oncol. 1989 Jan;25(1):149-53 [2920764.001]
  • [Cites] Tumori. 1998 Jul-Aug;84(4):472-7 [9824999.001]
  • [Cites] Neurology. 1997 Aug;49(2):452-6 [9270576.001]
  • [Cites] Spinal Cord. 2002 Jul;40(7):363-6 [12080464.001]
  • [Cites] J Neurooncol. 1992 Feb;12(2):141-4 [1560260.001]
  • [Cites] J Neurooncol. 1990 Jun;8(3):275-80 [2162918.001]
  • [Cites] Acta Radiol Oncol. 1983;22(2):135-43 [6310968.001]
  • [Cites] J Bone Joint Surg Br. 1999 Sep;81(5):830-4 [10530845.001]
  • [Cites] Ann Neurol. 1980 Oct;8(4):361-6 [7436380.001]
  • [Cites] J Neurooncol. 1985;3(1):77-84 [3998791.001]
  • [Cites] Radiother Oncol. 2001 Sep;60(3):281-8 [11514008.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Jul 15;32(4):959-67 [7607970.001]
  • [Cites] Ann Oncol. 2001 Aug;12(8):1173-7 [11583203.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2003 Jun;15(4):211-7 [12846501.001]
  • [Cites] Arch Neurol. 2000 May;57(5):690-5 [10815135.001]
  • [Cites] Neurosurgery. 2003 Jan;52(1):140-6; discussion 146-7 [12493111.001]
  • [Cites] Cancer. 1993 Nov 1;72(9):2583-8 [8402479.001]
  • [Cites] Br J Radiol. 2001 Jan;74(877):15-23 [11227772.001]
  • [Cites] J Neurosurg. 1991 Jan;74(1):70-5 [1845814.001]
  • [Cites] Clin Orthop Relat Res. 2003 Oct;(415 Suppl):S120-8 [14600601.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Nov 15;54(4):1160-4 [12419444.001]
  • [Cites] Neurology. 1987 Jan;37(1):134-8 [2948135.001]
  • [Cites] Eur Radiol. 1998;8(8):1345-51 [9853211.001]
  • [Cites] J Neurosurg. 2001 Jan;94(1 Suppl):25-37 [11147865.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1984 Aug;47(8):761-8 [6470717.001]
  • [Cites] Cancer. 1989 Dec 1;64(11):2207-13 [2804911.001]
  • [Cites] Childs Nerv Syst. 1997 Jul;13(7):383-7 [9298274.001]
  • [Cites] Clin Neurol Neurosurg. 2002 May;104(2):152-6 [11932047.001]
  • [Cites] Neurosurgery. 1990 Nov;27(5):755-9 [2259405.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1999 May;66(5):623-7 [10209174.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Mar 1;55(3):583-93 [12573745.001]
  • [Cites] J Clin Oncol. 1998 Apr;16(4):1613-24 [9552073.001]
  • [Cites] Neurosurgery. 1991 Nov;29(5):645-50 [1961391.001]
  • [Cites] Radiographics. 1991 Mar;11(2):219-32 [2028061.001]
  • [Cites] Spine (Phila Pa 1976). 1996 Sep 15;21(18):2143-8 [8893440.001]
  • [Cites] Eur J Cancer. 1994;30A(1):22-7 [8142159.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Mar 15;46(5):1163-9 [10725627.001]
  • [Cites] J Pediatr. 1984 Feb;104(2):221-4 [6694014.001]
  • [Cites] Acta Radiol. 1990 Mar;31(2):187-90 [2372462.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Oct 15;33(3):595-8 [7558948.001]
  • [Cites] Ann Neurol. 1982 Jan;11(1):28-34 [6174073.001]
  • (PMID = 16215815.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 125
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18. Mohammadianpanah M, Vasei M, Mosalaei A, Omidvari S, Ahmadloo N: Malignant spinal cord compression in cancer patients may be mimicked by a primary spinal cord tumour. Eur J Cancer Care (Engl); 2006 Dec;15(5):497-500
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant spinal cord compression in cancer patients may be mimicked by a primary spinal cord tumour.
  • Although it is quite rare, second primary neoplasms in cancer patients may present with the signs and symptoms of malignant spinal cord compression.
  • Primary spinal cord tumours in the cancer patients may be deceptive and considered as the recurrent first cancer.
  • We report such a case of intramedullary ependymoma of the cervical spinal cord mimicking metatstatic recurrent lymphoma and causing cord compression.
  • A 50-year-old man developed intramedullary ependymoma of the cervical spinal cord 1.5 years following chemoradiation for Waldeyer's ring lymphoma.
  • Magnetic resonance imaging revealed an intramedullary expansive lesion extending from C4 to C6 levels of the cervical spinal cord.
  • The development of the intramedullary ependymoma following treating lymphoma has not been reported.
  • [MeSH-major] Ependymoma / diagnosis. Neoplasms, Second Primary / diagnosis. Spinal Cord Compression / etiology. Spinal Cord Neoplasms / diagnosis
  • [MeSH-minor] Cervical Vertebrae. Diagnosis, Differential. Humans. Lymphoma, Non-Hodgkin / drug therapy. Lymphoma, Non-Hodgkin / radiotherapy. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Oropharyngeal Neoplasms / drug therapy. Oropharyngeal Neoplasms / radiotherapy. Quadriplegia / etiology

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  • (PMID = 17177910.001).
  • [ISSN] 0961-5423
  • [Journal-full-title] European journal of cancer care
  • [ISO-abbreviation] Eur J Cancer Care (Engl)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 10
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19. Yang KY, Li SH, Lin JW, Su TM, Ho JT, Chen WF: Concurrent chemoradiotherapy for primary cervical spinal cord germinoma. J Clin Neurosci; 2009 Jan;16(1):115-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent chemoradiotherapy for primary cervical spinal cord germinoma.
  • We report a rare case of primary intramedullary germinoma in the cervical spine of a 39-year-old woman without evidence of intracranial or disseminated disease.
  • This is the only reported case of primary spinal cord germinoma for which concurrent chemoradiotherapy was given.
  • Furthermore, this is only the second reported case of histologically documented primary intramedullary cervical spinal cord germinoma.
  • [MeSH-major] Drug Therapy / methods. Germinoma / therapy. Radiosurgery / methods. Spinal Cord Neoplasms / therapy

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  • (PMID = 19008102.001).
  • [ISSN] 0967-5868
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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20. Nakadate M, Harad M, Isobe H: [Clinical features of intradural spinal cord metastases in primary lung cancer]. Nihon Kokyuki Gakkai Zasshi; 2005 Sep;43(9):541-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical features of intradural spinal cord metastases in primary lung cancer].
  • We retrospectively investigated the clinical features of 9 consecutive cases of intradural spinal cord metastasis from primary lung cancer treated at our hospital between April 1999 and March 2002.
  • During those three years, spinal cord metastasis was diagnosed in seven of 49 (14.3%) cases with small cell carcinoma and only two of 284 (0.7%) cases with non-small cell carcinoma.
  • Eight of the 9 cases had concomitant brain metastasis that preceded spinal cord metastasis and had received brain irradiation.
  • The interval from brain irradiation to the diagnosis of spinal cord metastasis ranged from 116 to 708 days (median 183 days).
  • Seven of the patients rapidly developed transverse myelopathy within two weeks.
  • Magnetic resonance imaging (MRI) with contrast enhancement demonstrated intramedullary tumors in seven cases and intradural extramedullary tumors in two cases.
  • Spinal cord metastasis was often multifocal, and in each case lumbar enlargement was commonly involved.
  • Radiation therapy with or without concurrent chemotherapy produced both neurologic improvement and a tumor response shown on MRI in 4 patients.
  • Heightened awareness of the increasing incidence and background risk factors of this unusual complication could lead to earlier diagnosis and more effective treatment for neurologic palliation.
  • [MeSH-major] Lung Neoplasms / pathology. Spinal Cord / pathology. Spinal Cord Neoplasms / radiotherapy. Spinal Cord Neoplasms / secondary

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  • (PMID = 16218424.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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21. Kolasa M, Jesionek-Kupnicka D, Kordek R, Kolasa P: Primary spinal cord melanoma - a case report. Folia Neuropathol; 2010;48(3):212-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary spinal cord melanoma - a case report.
  • Authors present a case of a 57-year-old woman with primary spinal cord malignant melanoma.
  • Intramedullary localization of primary melanoma is extremely rare.
  • Surgical treatment with total removal of tumor was performed.
  • Subsequent chemotherapy was given.
  • Tumor was successfully treated by neurosurgery; radio- and chemotherapy with disease free follow up of 9 months.
  • Surgical treatment of melanoma in this location is extremely important as it leads to regression of neurological symptoms and improvement of the quality of life.

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  • (PMID = 20925006.001).
  • [ISSN] 1509-572X
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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22. Huang JH, Tsui I, Judkins AR, Simon E, Birknes JK, Sutton LN: Intramedullary cervical spine germinoma: case report. Neurosurgery; 2004 Dec;55(6):1432
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intramedullary cervical spine germinoma: case report.
  • OBJECTIVE AND IMPORTANCE: We report an extremely rare case of primary intramedullary germinoma in the cervical spinal cord arising in an 18-year-old man who had not undergone previous surgery or irradiation.
  • A postoperative magnetic resonance imaging scan of the brain and spinal cord did not show any other tumors.
  • The patient received local radiation as well as three courses of chemotherapy.
  • CONCLUSION: To our knowledge, this is the first report of an intramedullary cervical spine germinoma with confirmed tissue diagnosis.
  • Although extremely uncommon, the possibility of germinoma should be included in the differential diagnosis for primary intramedullary spinal cord tumors.
  • [MeSH-major] Cervical Vertebrae / pathology. Germinoma / diagnosis. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 15574227.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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23. Benes V 3rd, Barsa P, Benes V Jr, Suchomel P: Prognostic factors in intramedullary astrocytomas: a literature review. Eur Spine J; 2009 Oct;18(10):1397-422

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic factors in intramedullary astrocytomas: a literature review.
  • Astrocytomas affect a significant portion of patients with intramedullary tumors.
  • These infiltratively growing tumors are treated by a variety of methods -- biopsy and decompressive surgery, maximal safe resection, adjuvant oncological therapy.
  • Better understanding of factors that influence prognosis may help in treatment planning with the goal of prolonging survival.
  • For both low- and high-grade (HG) astrocytomas, maximal safe tumor resection should be the primary treatment objective but is often not feasible in contrast to other intramedullary and spinal neoplasms.
  • Since the biological nature of spinal cord HG glioma is identical to that of the brain, the same treatment algorithm of maximal safe resection followed by concomitant radio- and chemotherapy would be sensible to implement.
  • [MeSH-major] Astrocytoma / diagnosis. Astrocytoma / therapy. Spinal Cord / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Drug Therapy / methods. Humans. Neoplasm Invasiveness / pathology. Neurosurgical Procedures / methods. Prognosis. Radiotherapy / methods

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  • [Cites] J Neurooncol. 2001 May;53(1):61-6 [11678433.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Feb 1;52(2):316-24 [11872276.001]
  • [Cites] Neuro Oncol. 2003 Jul;5(3):208-13 [12816727.001]
  • [Cites] Neurosurgery. 2003 Jul;53(1):110-20; discussion 120-2 [12823880.001]
  • [Cites] Cancer. 2003 Aug 1;98(3):554-61 [12879473.001]
  • [Cites] Am J Roentgenol Radium Ther Nucl Med. 1969 Mar;105(3):659-64 [5775022.001]
  • [Cites] Cancer. 1975 Jun;35(6):1558-62 [1148990.001]
  • [Cites] J Neurol Neurosurg Psychiatry. 1976 Mar;39(3):290-6 [932744.001]
  • [Cites] Paraplegia. 1977 Nov;15(3):262-73 [201902.001]
  • [Cites] Cancer. 1978 May;41(5):1751-60 [417797.001]
  • [Cites] Radiology. 1980 May;135(2):473-9 [7367644.001]
  • [Cites] J Neurosurg. 1981 Mar;54(3):323-30 [7463133.001]
  • [Cites] Pediatr Neurosurg. 1997 Jul;27(1):34-9 [9486834.001]
  • [Cites] Childs Nerv Syst. 1998 Jul;14(7):317-21 [9726582.001]
  • [Cites] Cancer. 1998 Dec 1;83(11):2391-9 [9840540.001]
  • [Cites] Radiat Oncol Investig. 1998;6(6):276-80 [9885944.001]
  • [Cites] Childs Nerv Syst. 1999 Jan;15(1):17-28 [10066016.001]
  • [Cites] Pediatr Neurosurg. 1999 Jan;30(1):1-5 [10202299.001]
  • [Cites] Am J Clin Oncol. 1999 Aug;22(4):344-51 [10440187.001]
  • [Cites] J Neurosurg Spine. 2005 Mar;2(3):249-55 [15796348.001]
  • [Cites] Neurosurgery. 2005 May;56(5):972-81; discussion 972-81 [15854245.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2005 Sep 1;63(1):91-100 [16111576.001]
  • [Cites] Lancet. 2005 Sep 17-23;366(9490):985-90 [16168780.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Mar 15;64(4):1060-71 [16373081.001]
  • [Cites] Spinal Cord. 2006 Dec;44(12):740-5 [16670687.001]
  • [Cites] Acta Neurochir (Wien). 2008 Apr;150(4):371-9; discussion 379 [18176774.001]
  • [Cites] Eur Spine J. 2008 Mar;17(3):327-35 [18026865.001]
  • [Cites] Spinal Cord. 2008 Apr;46(4):282-6 [17909556.001]
  • [Cites] Neurosurgery. 2008 Apr;62(4):753-64; discussion 264-6 [18496181.001]
  • [Cites] Neurosurgery. 2008 Jul;63(1):55-60; discussion 60-1 [18728568.001]
  • [Cites] Pediatr Neurosurg. 1997 Jul;27(1):12-8 [9486831.001]
  • [Cites] Br J Cancer. 1999 Nov;81(5):835-40 [10555754.001]
  • [Cites] J Clin Neurosci. 2000 Jan;7(1):20-3 [10847645.001]
  • [Cites] J Neurosurg. 2000 Oct;93(2 Suppl):183-93 [11012047.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Oct 1;48(3):837-42 [11020582.001]
  • [Cites] J Neurooncol. 2001 Mar;52(1):85-94 [11451207.001]
  • [Cites] Cancer. 1982 Aug 15;50(4):732-5 [7093908.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1982 May;8(5):925-9 [7107424.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1982 Jun;8(6):999-1003 [7107442.001]
  • [Cites] J Neurosurg. 1982 Nov;57(5):685-9 [7131070.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1985 Nov;11(11):1933-9 [2997089.001]
  • [Cites] J Neurosurg. 1985 Nov;63(5):669-75 [4056869.001]
  • [Cites] Adv Tech Stand Neurosurg. 1986;13:135-69 [3510623.001]
  • [Cites] J Neurosurg. 1987 Apr;66(4):621-5 [3031241.001]
  • [Cites] Childs Nerv Syst. 1987;3(2):89-92 [3040249.001]
  • [Cites] J Neurosurg. 1989 Jan;70(1):50-4 [2909688.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1989 Jun;16(6):1397-403 [2542194.001]
  • [Cites] J Neurosurg. 1989 Dec;71(6):842-5 [2585075.001]
  • [Cites] Neurosurgery. 1989 Dec;25(6):855-9 [2601814.001]
  • [Cites] J Neurosurg. 1990 Apr;72(4):523-32 [2319309.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):3-8 [2380091.001]
  • [Cites] Neurosurgery. 1990 Aug;27(2):193-6 [2385335.001]
  • [Cites] Neurosurgery. 1991 Nov;29(5):651-6; discussion 656-7 [1961392.001]
  • [Cites] Neurosurgery. 1992 Apr;30(4):490-3 [1584345.001]
  • [Cites] J Neurosurg. 1992 Sep;77(3):355-9 [1506881.001]
  • [Cites] Clin Neurosurg. 1992;39:361-87 [1458751.001]
  • [Cites] J Neurosurg. 1993 Aug;79(2):204-9 [8331401.001]
  • [Cites] Br J Neurosurg. 1993;7(5):473-81 [8267886.001]
  • [Cites] Radiother Oncol. 1993 Dec;29(3):294-300 [8127979.001]
  • [Cites] J Neurosurg. 1994 Oct;81(4):507-12 [7931582.001]
  • [Cites] Neurosurgery. 1994 Jul;35(1):69-74; discussion 74-6 [7936155.001]
  • [Cites] Neurosurgery. 1994 Nov;35(5):865-73; discussion 873 [7838335.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Sep 30;33(2):323-8 [7673019.001]
  • [Cites] J Neurosurg. 1995 Oct;83(4):590-5 [7674006.001]
  • [Cites] Eur Spine J. 1996;5(4):243-50 [8886736.001]
  • [Cites] J Neurosurg. 1996 Dec;85(6):1036-43 [8929492.001]
  • [Cites] Childs Nerv Syst. 1996 Dec;12(12):776-80 [9118146.001]
  • [Cites] Childs Nerv Syst. 1997 Feb;13(2):108-12 [9105749.001]
  • [Cites] Clin Neurol Neurosurg. 1997 Feb;99(1):1-5 [9107459.001]
  • [Cites] J Neurooncol. 1997 Jul;33(3):205-11 [9195492.001]
  • [Cites] Childs Nerv Syst. 1997 Jul;13(7):375-82 [9298273.001]
  • [Cites] Pediatr Neurosurg. 1997 May;26(5):247-54 [9440494.001]
  • [Cites] J Neurosurg. 1998 Feb;88(2):215-20 [9452226.001]
  • (PMID = 19562388.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 76
  • [Other-IDs] NLM/ PMC2899373
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24. Godard J, Viennet G, Raul JS, Plouvier E, Miny J, Jacquet G, Czorny A: [Intramedullary spread of a cerebral oligodendroglioma. Two case reports]. Neurochirurgie; 2000 Dec;46(6):558-562
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Intramedullary spread of a cerebral oligodendroglioma. Two case reports].
  • We report two cases of leptomeningeal metastatic dissemination to the spinal cord of a grade B oligodendroglioma.
  • The pathways by which the intramedullary part of the spinal is reached by metastatic cells remains controversial.
  • In the reported cases, both frontal and cystic primary intracerebral lesions were observed.
  • Chemotherapy after radiotherapy appears to improve outcome.
  • [MeSH-major] Brain Neoplasms / pathology. Frontal Lobe. Oligodendroglioma / secondary. Spinal Cord Neoplasms / secondary
  • [MeSH-minor] Abducens Nerve Diseases / etiology. Antineoplastic Agents, Alkylating / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Carmustine / therapeutic use. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Etoposide / administration & dosage. Fatal Outcome. Female. Humans. Intracranial Hypertension / etiology. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Paralysis / etiology. Prognosis. Radiotherapy, Adjuvant

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  • (PMID = 11148408.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 6PLQ3CP4P3 / Etoposide; BG3F62OND5 / Carboplatin; U68WG3173Y / Carmustine
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25. Jalali K, Chautard D, Racineux P, Pabot du Chatelard P: [Spinal cord metastasis from prostate cancer]. Prog Urol; 2004 Sep;14(4):554-7; discussion 557
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  • [Title] [Spinal cord metastasis from prostate cancer].
  • The majority of spinal cord lesions observed in prostate cancer are related to extradural compression.
  • Intradural (extramedullary or intramedullary) metastases are very rare.
  • Despite endocrine therapy initiated immediately after diagnosis, the patient rapidly developed leg pain due to vertebral osteolysis.
  • He developed flaccid paraplegia despite radiotherapy of the lumbar spine combined with corticosteroid therapy and chemotherapy.
  • Spinal cord magnetic resonance imaging (MRI) showed typical features of very probable carcinomatous myelitis in the cervicothoracic zone.
  • Regardless of the primary cancer, intramedullary spinal cord metastases have a very poor prognosis.
  • [MeSH-major] Adenocarcinoma / secondary. Prostatic Neoplasms / pathology. Spinal Neoplasms / secondary

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  • (PMID = 15776912.001).
  • [ISSN] 1166-7087
  • [Journal-full-title] Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie
  • [ISO-abbreviation] Prog. Urol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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26. Biswas A, Puri T, Goyal S, Gupta R, Eesa M, Julka PK, Rath GK: Spinal intradural primary germ cell tumour--review of literature and case report. Acta Neurochir (Wien); 2009 Mar;151(3):277-84

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal intradural primary germ cell tumour--review of literature and case report.
  • BACKGROUND: Primary spinal cord germ cell tumour is a rare tumour.
  • We herein review the tumour characteristics, associated risk factors, treatment policy, and patterns of failure of primary intradural germ cell tumour.
  • METHOD: We conducted a PUBMED search using a combination of keywords such as "spinal germ cell tumor," "germinoma," "extradural," "intradural," "intramedullary," "extramedullary," and identified 19 cases of primary spinal germ cell tumour.
  • Clinical features, pathologic characteristics, and treatment details of these patients including status at follow-up were noted from respective case reports.
  • We also describe a case of a young Indian patient of intradural extramedullary germ cell tumour treated with a combination of surgery, chemotherapy, and radiotherapy.
  • Most patients were treated with a combination of surgery, radiation therapy, and systemic chemotherapy.
  • Magnetic resonance imaging spine showed an inhomogeneous hyperintense soft tissue mass at L(2)-L(4) spinal level.
  • He was treated with complete surgical excision and four cycles of chemotherapy with BEP regimen following a histological diagnosis of non-seminomatous germ cell tumour.
  • The patient eventually succumbed to his condition, due to compressive transverse myelitis possibly due to cervical cord metastasis.
  • CONCLUSION: Limited surgery followed by upfront radiation therapy and adjuvant chemotherapy is the optimal management of this rare group of tumour.
  • Omission of radiation therapy from the treatment armamentarium might engender local recurrence and spinal dissemination at first failure.
  • [MeSH-major] Neoplasms, Germ Cell and Embryonal / pathology. Neoplasms, Germ Cell and Embryonal / therapy. Spinal Cord / pathology. Spinal Cord Neoplasms / pathology. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Biomarkers, Tumor / analysis. Biomarkers, Tumor / metabolism. Chorionic Gonadotropin, beta Subunit, Human / analysis. Chorionic Gonadotropin, beta Subunit, Human / metabolism. Decompression, Surgical. Disease Progression. Fatal Outcome. Humans. Lumbar Vertebrae. Magnetic Resonance Imaging. Male. Myelitis, Transverse / etiology. Neoplasm Metastasis / pathology. Neoplasm Recurrence, Local / radiotherapy. Neurosurgical Procedures. Radiotherapy. Subarachnoid Space / pathology. Subarachnoid Space / surgery

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  • [CommentIn] Acta Neurochir (Wien). 2009 Aug;151(8):983-4 [19337687.001]
  • (PMID = 19240975.001).
  • [ISSN] 0942-0940
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Austria
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin, beta Subunit, Human
  • [Number-of-references] 41
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27. Herrlinger U, Weller M, Küker W: Primary CNS lymphoma in the spinal cord: clinical manifestations may precede MRI detectability. Neuroradiology; 2002 Mar;44(3):239-44
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary CNS lymphoma in the spinal cord: clinical manifestations may precede MRI detectability.
  • Eight months later, after progression to tetraparesis and demonstration of an extensive contrast-enhancing intramedullary lesion giving high signal on T2-weighted images, the diagnosis of lymphoblastic non-Hodgkin's lymphoma was made by biopsy.
  • The lesion responded for a short time to corticosteroid medication, but later rapidly extended to the epidural soft tissues, probably due to a cerebrospinal fluid fistula.
  • Despite radio-and chemotherapy, the patient survived only 7 months from histological diagnosis and 15 months from the onset of symptoms.
  • [MeSH-major] Magnetic Resonance Imaging. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis. Spinal Cord Neoplasms / diagnosis

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  • (PMID = 11942380.001).
  • [ISSN] 0028-3940
  • [Journal-full-title] Neuroradiology
  • [ISO-abbreviation] Neuroradiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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28. Nishihara M, Sasayama T, Kondoh T, Tanaka K, Kohmura E, Kudo H: Long-term survival after surgical resection of primary spinal malignant melanoma. Neurol Med Chir (Tokyo); 2009 Nov;49(11):546-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival after surgical resection of primary spinal malignant melanoma.
  • He had a history of primary spinal intramedullary malignant melanoma at the T6 level 18 years previously, which had remained stable for 18 years.
  • Whole brain radiation therapy (30 Gy), local radiation therapy (15 Gy), and routine intrathecal injection of interferon beta were performed.
  • The prognosis for primary CNS malignant melanomas better than that for cutaneous melanoma.
  • The unusually long survival in the present case indicates the effectiveness of the combined radiotherapy and interferon therapy.
  • [MeSH-major] Melanoma / mortality. Melanoma / therapy. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / therapy. Spinal Cord Neoplasms / mortality. Spinal Cord Neoplasms / therapy
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Combined Modality Therapy / methods. Disease Progression. Disease-Free Survival. Headache / etiology. Humans. Interferon-beta / therapeutic use. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Metastasis / drug therapy. Neoplasm Metastasis / pathology. Neoplasm Metastasis / radiotherapy. Prognosis. Radiotherapy / methods. Spinal Cord / pathology. Spinal Cord / physiopathology. Time Factors. Treatment Outcome

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  • (PMID = 19940408.001).
  • [ISSN] 1349-8029
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 77238-31-4 / Interferon-beta
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29. Abel TJ, Chowdhary A, Thapa M, Rutledge JC, Geyer JR, Ojemann J, Avellino AM: Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature. J Neurosurg; 2006 Dec;105(6 Suppl):508-14
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord pilocytic astrocytoma with leptomeningeal dissemination to the brain. Case report and review of the literature.
  • Leptomeningeal dissemination of low-grade spinal cord gliomas is an uncommon event.
  • The authors report a unique case of leptomeningeal dissemination of a spinal cord pilocytic astrocytoma (PCA) to the intracranial cerebral subarachnoid spaces in a child.
  • An intradural intramedullary spinal cord tumor was identified, and the lesion was subtotally resected and diagnosed by the pathology department to be a PCA.
  • Subsequently, the patient had recurrences of the intradural intramedullary tumor at 6 months and 2 years after his original presentation.
  • The patient then underwent chemotherapy, and total spine magnetic resonance (MR) imaging 2 months later demonstrated stability in the size of the spinal cord tumor and a decrease in the associated syrinx.
  • However, an MR image of the head demonstrated two new areas of supratentorial subarachnoid leptomeningeal spread of the primary spinal cord tumor at the 2-month follow-up examination.
  • This case illustrates a unique instance of supratentorial leptomeningeal dissemination of an intramedullary spinal cord PCA in a child.
  • [MeSH-major] Astrocytoma / secondary. Brain Neoplasms / secondary. Meningeal Neoplasms / secondary. Spinal Cord Neoplasms / pathology


30. Oshiro S, Komatsu F, Tsugu H, Nabeshima K, Abe H, Ohkawa M, Inoue T: [A case of intramedullary cervical metastasis from cerebellar anaplastic oligodendroglioma without typical MR appearance for CSF dissemination]. No Shinkei Geka; 2010 Mar;38(3):279-85
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  • [Title] [A case of intramedullary cervical metastasis from cerebellar anaplastic oligodendroglioma without typical MR appearance for CSF dissemination].
  • We report a case of intramedullary cervical metastasis from cerebellar anaplastic oligodendroglioma without any MR appearance for CSF dissemination or recurrence in the primary tumor site.
  • The case was a 73-year-old female who underwent tumor resection for cerebellar anaplastic oligodendroglioma following irradiation and TMZ chemotherapy.
  • One year and a half later, a small nodular lesion developed at the temporal lobe.
  • While treatment with TMZ was restarted during the course, another intramedullary cervical lesion produced additionally without any CSF dissemination or recurrence at the primary site.
  • The histological examination obtained in spinal surgery revealed evidence of similar features consistent with a previous cerebellar tumor with anaplastic oligodendroglioma.
  • Although CSF dissemination by malignant glioma with leptomeningeal enhancement is relatively well recognized at their terminal stage, cases with intramedullary cervical metastasis without any leptomeningeal enhancement have only been rarely described.
  • We discussed the mechanisms of intramedullary cervical metastasis from intracranial malignant glioma.
  • [MeSH-major] Cerebellar Neoplasms / pathology. Oligodendroglioma / pathology. Spinal Cord Neoplasms / secondary

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  • (PMID = 20229774.001).
  • [ISSN] 0301-2603
  • [Journal-full-title] No shinkei geka. Neurological surgery
  • [ISO-abbreviation] No Shinkei Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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31. Birbilis TA, Matis GK, Eleftheriadis SG, Theodoropoulou EN, Sivridis E: Spinal metastasis of glioblastoma multiforme: an uncommon suspect? Spine (Phila Pa 1976); 2010 Apr 1;35(7):E264-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal metastasis of glioblastoma multiforme: an uncommon suspect?
  • Spinal metastases of this malignancy are quite rare and dissemination usually occurs late in the course of the disease.
  • However, recent advances in cancer treatment prolongate survival and provide adequate time for these metastases to give clinical symptoms.
  • METHODS: We hereby present a case of a 57-year-old woman with a history of pineal GBM treated by stereotactic biopsy, chemotherapy, and radiotherapy, readmitted 38 months later due to gait disturbance, spastic paraparesis, edema of lower limbs, bilateral positive Babinski response, and loss of bladder control.
  • A contrast-enhanced magnetic resonance imaging demonstrated an intramedullary lesion extending from C7 to T3 level.
  • No further treatment was given, and the patient died 2 months after the diagnosis of the spinal metastasis.
  • CONCLUSION: Spinal metastases should be commonly suspected in patients with a history of intracranial GBM who complain about symptoms not explained by the primary lesion.Glioblastoma multiforme (GBM) was first described by Rudolph Virchow in 1863 and represents the most common and most malignant tumor of the cerebral hemispheres, usually arising between the ages of 40 and 60 years.
  • However, when GBM is under apparent control, spinal metastases are clinically rarely detected.
  • Although involvement of the spinal cord (SC) has been noted with increasing frequency in recent years, literature provides only a few well documented cases.
  • [MeSH-major] Brain Neoplasms / pathology. Glioblastoma / secondary. Pineal Gland / pathology. Spinal Neoplasms / secondary

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  • (PMID = 20195200.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Albrecht CF, Weiss E, Schulz-Schaeffer WJ, Albrecht T, Fauser S, Wickboldt J, Hess CF: Primary intraspinal primitive neuroectodermal tumor: report of two cases and review of the literature. J Neurooncol; 2003 Jan;61(2):113-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary intraspinal primitive neuroectodermal tumor: report of two cases and review of the literature.
  • BACKGROUND: Primary intraspinal primitive neuroectodermal tumor (PNET) is a very rare tumor entity.
  • The optimal therapeutic approach is not known yet.
  • We report on two women with primary intraspinal PNETs and review the literature.
  • We describe the typical course of the disease, compare our patients to the other 17 cases reported until today, and discuss therapeutic options.
  • Postoperative radiation was performed from T12 to L3 to a dose of 50.4 Gy.
  • Subsequently she was treated with chemotherapy containing vincristine, cisplatinum and lomustine.
  • Case B: A 29-year-old woman presented with intramedullary PNET lesions at T1-3 and T10-11.
  • Due to the multifocal location, she received a primary craniospinal axis irradiation to a dose of 35.2 Gy plus a boost to the tumor region to a total dose of 53.2 Gy.
  • RESULTS: Both patients developed multilocular intraspinal relapses with meningeosis neoplastica 17 and 6 months from radiation therapy and underwent palliative chemotherapy.
  • Case A died 23 months, case B 17 months after primary diagnosis.
  • CONCLUSION: Despite modern treatment with microsurgery, irradiation and chemotherapy in primary intraspinal PNETs, local relapse or dissemination in most cases lead to death within a few months.
  • An improvement of treatment outcome can only be achieved by intensification through multidisciplinary treatment.
  • [MeSH-major] Medulla Oblongata / pathology. Neuroectodermal Tumors, Primitive, Peripheral / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols. Combined Modality Therapy. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

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  • [Cites] Neurosurgery. 1997 Dec;41(6):1417-20 [9402596.001]
  • [Cites] Hum Pathol. 2000 Aug;31(8):999-1001 [10987262.001]
  • [Cites] J Neurosurg. 1990 Apr;72(4):572-82 [2319316.001]
  • [Cites] J Neurosurg. 1978 May;48(5):741-6 [641553.001]
  • [Cites] J Clin Oncol. 1995 Jul;13(7):1687-96 [7602359.001]
  • [Cites] Pediatr Neurosci. 1989;15(4):181-7 [2562067.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Jul;19(1):219-21 [2380087.001]
  • [Cites] Acta Neurochir (Wien). 1999;141(11):1169-75 [10592116.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1999 Jan 15;43(2):279-85 [10030250.001]
  • [Cites] J Comput Tomogr. 1987 Oct;11(4):350-4 [2832122.001]
  • [Cites] AJNR Am J Neuroradiol. 1987 Nov-Dec;8(6):1151-2 [2825497.001]
  • [Cites] J Neurosurg. 1991 Mar;74(3):433-40 [1847194.001]
  • [Cites] Neurosurgery. 1996 Feb;38(2):265-71 [8869053.001]
  • [Cites] Hum Pathol. 1983 Jun;14(6):538-50 [6303940.001]
  • [Cites] J Neurosurg. 1969 Jul;31(1):50-8 [4307543.001]
  • [Cites] Clin Neuropathol. 1985 Jan-Feb;4(1):1-11 [2983916.001]
  • [Cites] Radiother Oncol. 1992 Jun;24(2):77-81 [1323134.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1991 May 15;21(1):109-22 [2032882.001]
  • [Cites] Neuroradiology. 1994 Apr;36(3):228-30 [8041447.001]
  • [Cites] J Neuropathol Exp Neurol. 1983 Jan;42(1):1-15 [6296325.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2000 Jan 15;46(2):269-79 [10661332.001]
  • [Cites] J Neurooncol. 1985;3(1):23-33 [2987425.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Dec 1;36(5):1155-61 [8985038.001]
  • [Cites] Neurosurg Rev. 1988;11(3-4):259-65 [3251169.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1990 Aug;19(2):265-74 [2394606.001]
  • [Cites] Cancer. 1973 Oct;32(4):890-7 [4751919.001]
  • [Cites] Cancer. 2000 May 1;88(9):2189-93 [10813733.001]
  • [Cites] Cancer. 1984 Jul 15;54(2):353-6 [6327008.001]
  • (PMID = 12622449.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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33. Gilmer-Hill HS, Ellis WG, Imbesi SG, Boggan JE: Spinal oligodendroglioma with gliomatosis in a child. Case report. J Neurosurg; 2000 Jan;92(1 Suppl):109-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal oligodendroglioma with gliomatosis in a child. Case report.
  • The authors present a rare case of oligodendrogliomatosis in a child, which they believe originated from a primary spinal cord tumor.
  • At 2.5 years of age this boy developed poor balance, neck stiffness, and a regression in developmental milestones.
  • A computerized tomography (CT) scan of the head initially revealed ventriculomegaly and multiple cystic cerebellar lesions.
  • In addition, magnetic resonance (MR) imaging revealed a cystic intramedullary lesion involving the cervical spinal cord.
  • Despite having a complicated course, chemotherapy with carboplatin has provided the patient with long-term palliation and a high quality of life.
  • This case may represent the fifth report in the literature of oligodendrogliomatosis occurring in a child but only the third occurring with a spinal primary tumor.
  • [MeSH-major] Brain Neoplasms / pathology. Glioma / pathology. Neoplasms, Multiple Primary / pathology. Oligodendroglioma / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Child, Preschool. Combined Modality Therapy. Humans. Magnetic Resonance Imaging. Male. Palliative Care. Photomicrography. Tomography, X-Ray Computed


34. Luger NM, Honore P, Sabino MA, Schwei MJ, Rogers SD, Mach DB, Clohisy DR, Mantyh PW: Osteoprotegerin diminishes advanced bone cancer pain. Cancer Res; 2001 May 15;61(10):4038-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Bone cancer pain most commonly occurs when tumors originating in breast, prostate, or lung metastasize to long bones, spinal vertebrae, and/or pelvis.
  • Primary and metastatic cancers involving bone account for approximately 400,000 new cancer cases per year in the United States alone, and >70% of patients with advanced breast or prostate cancer have skeletal metastases.
  • To begin to define the mechanisms that give rise to advanced bone cancer pain, osteolytic 2472 sarcoma cells or media were injected into the intramedullary space of the femur of C3H/HeJ mice, and the injection hole was sealed using dental amalgam, confining the tumor cells to the bone.
  • Twelve days after injection of 2472 tumor cells, animals showed advanced tumor-induced bone destruction of the injected femur, bone cancer pain, and a stereotypic set of neurochemical changes in the spinal cord dorsal horn that receives sensory inputs from the affected femur.
  • The neurochemistry of the spinal cord was evaluated at days 12 and 21.
  • Results indicated that osteoprotegerin treatment halted further bone destruction, reduced ongoing and movement-evoked pain, and reversed several aspects of the neurochemical reorganization of the spinal cord.
  • [MeSH-major] Bone Neoplasms / complications. Glycoproteins / pharmacology. Pain / drug therapy
  • [MeSH-minor] Animals. Disease Models, Animal. Male. Mice. Mice, Inbred C3H. Neurons, Afferent / metabolism. Neurons, Afferent / physiology. Osteoclasts / drug effects. Osteoclasts / physiology. Osteolysis / complications. Osteolysis / drug therapy. Osteolysis / etiology. Osteoprotegerin. Proto-Oncogene Proteins c-fos / biosynthesis. Receptors, Cytoplasmic and Nuclear. Receptors, Tumor Necrosis Factor. Sarcoma, Experimental / complications. Sarcoma, Experimental / pathology. Spinal Cord / drug effects. Spinal Cord / pathology

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  • (PMID = 11358823.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / AR43595; United States / NIDA NIH HHS / DA / DA11986; United States / NIDCR NIH HHS / DE / DE00270; United States / NIDCR NIH HHS / DE / DE07288; United States / NINDS NIH HHS / NS / NS23970
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glycoproteins; 0 / Osteoprotegerin; 0 / Proto-Oncogene Proteins c-fos; 0 / Receptors, Cytoplasmic and Nuclear; 0 / Receptors, Tumor Necrosis Factor; 0 / Tnfrsf11b protein, mouse
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35. Kaal EC, Vecht CJ: CNS complications of breast cancer: current and emerging treatment options. CNS Drugs; 2007;21(7):559-79
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] CNS complications of breast cancer: current and emerging treatment options.
  • The choice of appropriate therapy for brain metastases also depends on prognostic factors, including the age of the patient, the Karnofsky performance score, the number of brain metastases and the presence of systemic disease.
  • Surgery followed by whole brain radiation therapy (WBRT) is generally restricted to ambulant patients with a single brain metastasis without active extracranial disease.
  • Although breast carcinoma is sensitive to chemotherapy, the role of chemotherapy in the treatment of brain metastases is still unclear.
  • Objective responses after cyclophosphamide-based therapies were reported in studies performed in the 1980s.
  • Breast cancer constitutes the most common solid primary tumour leading to leptomeningeal disease.
  • A randomised study in patients with leptomeningeal disease secondary to breast cancer has revealed that intrathecal chemotherapy is associated with substantially more adverse effects than non-intrathecal treatment, without a clear benefit in terms of response or survival.
  • Intramedullary metastasis is rare but often presents with a rapidly progressive myelopathy.
  • Epidural spinal cord metastasis occurs in approximately 4% of patients and can lead to paraplegia.
  • [MeSH-major] Brain Neoplasms / secondary. Brain Neoplasms / therapy. Breast Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Clinical Trials as Topic. Female. Humans. Incidence. Meningeal Neoplasms / diagnosis. Meningeal Neoplasms / secondary. Meningeal Neoplasms / therapy. Risk Factors. Spinal Cord Neoplasms / diagnosis. Spinal Cord Neoplasms / secondary. Spinal Cord Neoplasms / therapy


36. Jover-Diaz F, Rizo-Martinez A, del Moral-Gonzalez F, Sánchez-Heras B: [Multiple intramedullary metastasis]. Rev Neurol; 2003 May 1-15;36(9):899-900

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multiple intramedullary metastasis].
  • [MeSH-major] Carcinoma, Squamous Cell / secondary. Spinal Cord Neoplasms / secondary
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Mediastinal Neoplasms / drug therapy. Mediastinal Neoplasms / pathology. Middle Aged. Neoplasms, Second Primary. Tomography, X-Ray Computed

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  • (PMID = 12717680.001).
  • [ISSN] 0210-0010
  • [Journal-full-title] Revista de neurologia
  • [ISO-abbreviation] Rev Neurol
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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