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Items 1 to 27 of about 27
1. Hsueh SC, Chung MT, Fang R, Hsiung MC, Young MS, Lu HF: Primary cardiac lymphoma. J Chin Med Assoc; 2006 Apr;69(4):169-74
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  • [Title] Primary cardiac lymphoma.
  • Primary cardiac lymphoma (PCL) has rarely been reported in Chinese populations.
  • The clinical manifestations may be variable and are attributed to its location, the presence of congestive heart failure, pericardial effusion, arrhythmia, and cardiomegaly.
  • Imaging examinations are the best methods for initial diagnosis and include echocardiography, computed tomography (CT) scan, magnetic resonance imaging (MRI), and radioisotope scan.
  • However, the final diagnosis is made by pathology, such as cytologic examination of the effusive fluid and tissue biopsy.
  • Because the tumors are difficult to resect, the main treatment for the disease is chemotherapy, which can be successful.
  • By clinical staging, including chest X-ray, echocardiography, CT scan of the abdomen, MRI of the heart, whole body tumor Gallium scan, and gastrointestinal series, no metastatic lesion or involvement was found in other parts of the body.
  • Pathologic findings including cytology of pericardial effusion and heart tumor biopsy revealed the case as a diffuse large B-cell lymphoma.
  • After chemotherapy with COP (cyclophosphamide + vincristine + prednisone) and CHOPBE (COP + doxorubicin + bleomycin + etoposide) regimens, the intracardiac tumor had disappeared, but the patient survived for 12 months in total, despite additional radiotherapy over the pericardial lesions.
  • It was presumed that because the tumor was very large and involved all 3 layers of the heart, it did not respond as well to the therapy as expected.
  • [MeSH-major] Heart Neoplasms / therapy. Lymphoma / therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Echocardiography. Humans. Male. Middle Aged

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  • (PMID = 16689199.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China (Republic : 1949- )
  • [Number-of-references] 24
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2. Fujisaki J, Tanaka T, Kato J, Saito T, Yano K, Shimizu Y, Sada T, Kitazume K, Fujita A, Kira Y: Primary cardiac lymphoma presenting clinically as restrictive cardiomyopathy. Circ J; 2005 Feb;69(2):249-52
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  • [Title] Primary cardiac lymphoma presenting clinically as restrictive cardiomyopathy.
  • An unusual case of primary cardiac lymphoma presenting as restrictive cardiomyopathy with arrhythmia is reported in a 72-year-old woman who was admitted for evaluation of exertional dyspnea and palpitations.
  • Electrocardiography (ECG) showed atrioventricular dissociation and right heart cardiac catheterization revealed a typical 'dip-and-plateau' waveform.
  • Restrictive cardiomyopathy was suspected because computed tomography (CT) did not reveal pericardial thickening, calcifications, or an effusion.
  • Heart failure initially improved with diuretic therapy, but subsequently worsened, and the patient experienced a syncopal episode.
  • ECG showed atrial fibrillation, and CT revealed a large mass in the right atrium and multiple tumors in the liver, which needle biopsy confirmed as diffuse large B-cell lymphoma.
  • Chemotherapy induced complete remission, and her heart failure markedly improved.
  • Clinically, the diagnosis was primary cardiac lymphoma.
  • [MeSH-major] Cardiomyopathy, Restrictive / etiology. Heart Neoplasms / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis
  • [MeSH-minor] Aged. Arrhythmias, Cardiac / etiology. Cardiac Catheterization. Diagnosis, Differential. Electrocardiography. Female. Heart Block. Humans. Lymphoma, B-Cell / complications. Lymphoma, B-Cell / diagnosis. Remission Induction / methods. Tomography, X-Ray Computed

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  • (PMID = 15671623.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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3. Flox Camacho A, Hernández Hernández F, Salguero Bodes R, Sánchez Pérez I, Carbonell Porras A, Tascón Pérez J: [Primary cardiac lymphoma: diagnosis by transjugular biopsy]. Rev Esp Cardiol; 2003 Nov;56(11):1141-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary cardiac lymphoma: diagnosis by transjugular biopsy].
  • Primary cardiac lymphoma, defined as a non-Hodgkin's lymphoma involving only the heart and pericardium, is an extremely rare malignancy.
  • It should be suspected in patients with a heart mass and heart failure, unexplained refractory pericardial effusion or rhythm disturbances.
  • Transvenous intracardiac tumor biopsy under fluoroscopic or transesophageal echocardiographic guidance, is a minimally invasive technique which makes definite diagnosis possible.
  • We describe a patient in whom primary cardiac lymphoma was diagnosed by this technique.
  • He also underwent percutaneous balloon pericardiotomy because of severe refractory pericardial effusion.
  • Seven months after diagnosis and treatment with standard chemotherapy, the patient remained free of disease.
  • [MeSH-major] Heart Neoplasms / diagnosis. Lymphoma / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy, Needle. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Echocardiography, Doppler. Fluoroscopy. Humans. Jugular Veins / pathology. Jugular Veins / radiography. Male. Middle Aged. Pericardial Effusion / etiology. Pericardial Effusion / ultrasonography. Pericardiectomy. Prednisone / therapeutic use. Tomography, X-Ray Computed. Treatment Outcome. Vincristine / therapeutic use

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  • (PMID = 14622547.001).
  • [ISSN] 0300-8932
  • [Journal-full-title] Revista española de cardiología
  • [ISO-abbreviation] Rev Esp Cardiol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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4. Tanaka PY, Atala MM, Pereira J, Caterino-de-Araujo A: Primary effusion lymphoma with cardiac involvement in HIV positive patient-complete response and long survival with chemotherapy and HAART. J Clin Virol; 2009 Jan;44(1):84-5
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  • [Title] Primary effusion lymphoma with cardiac involvement in HIV positive patient-complete response and long survival with chemotherapy and HAART.
  • Primary effusion lymphoma (PEL) is a rare type of lymphoma related to herpesvirus-8 (HHV-8), and considered an AIDS-defining condition.
  • The authors describe a case of PEL with cardiac involvement occurring in an HIV-positive patient treated with HAART and chemotherapy, who achieved complete remission and long survival.
  • [MeSH-major] Antiretroviral Therapy, Highly Active. HIV Infections / complications. HIV Infections / drug therapy. HIV Long-Term Survivors. Heart Neoplasms / secondary. Lymphoma, Primary Effusion / complications. Lymphoma, Primary Effusion / diagnosis


5. Takenaka S, Mitsudo K, Inoue K, Goto T, Kadota K, Fujii S, Yamamoto H, Fuku Y, Hirono A, Tanaka H, Taba M, Ikeda A, Kojima Y, Maekawa J, Maekawa S, Takahashi N, Saeki H, Nakamura Y, Oonishi T, Ueda N: Successful treatment of primary cardiac lymphoma with atrioventricular nodal block. Int Heart J; 2005 Sep;46(5):927-31
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  • [Title] Successful treatment of primary cardiac lymphoma with atrioventricular nodal block.
  • However, she developed shortness of breath 2 months after the implantation.
  • Transthoracic echocardiography showed thickened left and right atrial walls with mild pericardial effusion.
  • A diagnosis was made based on a CT scan and histology.
  • Although most primary cardiac malignant lymphomas are associated with a poor prognosis, the patient was treated successfully with chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Block / complications. Heart Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy
  • [MeSH-minor] Aged. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Female. Humans. Pacemaker, Artificial. Prednisolone / administration & dosage. Vincristine / administration & dosage

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  • (PMID = 16272785.001).
  • [ISSN] 1349-2365
  • [Journal-full-title] International heart journal
  • [ISO-abbreviation] Int Heart J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VAP-cyclo protocol
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6. Kosugi M, Ono T, Yamaguchi H, Sato N, Dan K, Tanaka K, Takano T: Successful treatment of primary cardiac lymphoma and pulmonary tumor embolism with chemotherapy. Int J Cardiol; 2006 Jul 28;111(1):172-3
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  • [Title] Successful treatment of primary cardiac lymphoma and pulmonary tumor embolism with chemotherapy.
  • A 72-year-old man with a large mass in the right atrium and the pulmonary embolism by chest computed tomography was diagnosed as the primary cardiac B-cell lymphoma (PCL) with pulmonary tumor embolism and pericardial effusion.
  • Upon completion of initial chemotherapy, the mass was markedly reduced, and the pulmonary embolism disappeared on magnetic resonance imaging.
  • This rarely diagnosed entity is treatable with chemotherapy for both PCL and pulmonary embolism.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy. Neoplastic Cells, Circulating. Pulmonary Embolism / drug therapy. Pulmonary Embolism / etiology
  • [MeSH-minor] Aged. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Humans. Male. Prednisone / therapeutic use. Remission Induction. Vincristine / therapeutic use

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  • (PMID = 16129500.001).
  • [ISSN] 0167-5273
  • [Journal-full-title] International journal of cardiology
  • [ISO-abbreviation] Int. J. Cardiol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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7. Chin JY, Chung MH, Kim JJ, Lee JH, Kim JH, Maeng IH, Jung SY, Hwang HJ, Lee JB, Youn HJ: Extensive primary cardiac lymphoma diagnosed by percutaneous endomyocardial biopsy. J Cardiovasc Ultrasound; 2009 Dec;17(4):141-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extensive primary cardiac lymphoma diagnosed by percutaneous endomyocardial biopsy.
  • Primary cardiac lymphoma (PCL) is an extranodal non-Hodgkin's lymphoma exclusively located in the heart and/or pericardium.
  • It is rare in immunocompetent patients and represents 1.3% of primary cardiac tumors and 0.5% of extranodal lymphomas.
  • The clinical behavior is aggressive and the early symptoms are cardiac failure, syncope, arrhythmia, or pericardial effusion.
  • Although echocardiography, computed tomography (CT) scan, magnetic resonance image (MRI) are the mainly used imaging techniques to detect cardiac tumors, pathologic examination is always required to confirm the diagnosis.
  • Diagnosis of PCL is difficult due to non-specific clinical manifestations and requires invasive approach to get histopathologic evidence.
  • While surgery with systemic chemotherapy or in combination with irradiation has been attempted, the only effective treatment is chemotherapy.
  • We report on a 42-year-old woman who is diagnosed histopathologically as PCL by cardiac catheterization assisted percutaneous endomyocardial biopsy and treated successfully by anthracycline based chemotherapy.

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  • (PMID = 20661340.001).
  • [ISSN] 2005-9655
  • [Journal-full-title] Journal of cardiovascular ultrasound
  • [ISO-abbreviation] J Cardiovasc Ultrasound
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2889391
  • [Keywords] NOTNLM ; Cardiac tamponade / Non-Hodgkin's lymphoma / Pericardial effusion
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8. Nakakuki T, Masuoka H, Ishikura K, Seko T, Koyabu S, Tamai T, Sugawa M, Ito M, Nakano T: A case of primary cardiac lymphoma located in the pericardial effusion. Heart Vessels; 2004 Jul;19(4):199-202
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  • [Title] A case of primary cardiac lymphoma located in the pericardial effusion.
  • Primary cardiac lymphoma is a rare disorder with a poor prognosis.
  • We present here a case of 77-year-old woman who was diagnosed as having cardiac lymphoma antemortem according to a cytologic examination of the pericardial effusion.
  • Determination of the levels of serum-soluble interleukin-2 receptor and serum deoxythymidine kinase was useful for the diagnosis.
  • Echocardiography, computed tomography, magnetic resonance imaging, and gallium scan revealed neither lymphadenopathy nor tumor in the heart, so she was diagnosed as having malignant lymphoma that probably originated from the pericardium.
  • Systemic chemotherapy with CHOP (cyclophosphamide, farmorubicin, oncovin, and prednisolone) resulted in a complete resolution of the pericardial effusion.
  • She has been in remission 48 months after discontinuation of the chemotherapy.
  • [MeSH-major] Heart Neoplasms / diagnosis. Lymphoma / diagnosis. Pericardial Effusion / pathology
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Female. Humans. Prednisolone / therapeutic use. Vincristine / therapeutic use

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  • (PMID = 15278395.001).
  • [ISSN] 0910-8327
  • [Journal-full-title] Heart and vessels
  • [ISO-abbreviation] Heart Vessels
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VAP-cyclo protocol
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9. Yunoki K, Naruko T, Ohashi J, Fujimoto K, Shimamura K, Shirai N, Komatsu R, Sakanoue Y, Kubo Y, Hai E, Inoue T, Itoh A, Haze K: [Primary effusion lymphoma complicating cardiac tamponade: a case report]. J Cardiol; 2007 Apr;49(4):205-10
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  • [Title] [Primary effusion lymphoma complicating cardiac tamponade: a case report].
  • Chest radiography revealed marked cardiomegaly and echocardiography showed massive pericardial effusion mainly behind the left ventricle and collapse of the right ventricle.
  • The initial diagnosis was pericardial tamponade.
  • Pericardiocentesis and pericardial drainage revealed bloody pericardial effusion.
  • The cytological analysis of the pericardial effusion revealed numerous lymphoma cells.
  • Computed tomography of the neck, chest and abdomen showed no evidence of tumor masses, lymph node enlargement, or hepatosplenomegaly.
  • The final diagnosis was primary effusion lymphoma.
  • The prognosis of primary effusion lymphoma is generally unfavorable because it is frequently accompanied by immunodeficiency disease.
  • Fortunately, the effect of chemotherapy was excellent and the patient is doing well 1 year after the diagnosis.
  • [MeSH-major] Cardiac Tamponade / etiology. Heart Neoplasms / complications. Lymphoma, B-Cell / complications. Pericardial Effusion / complications. Pericardial Effusion / pathology

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  • (PMID = 17460882.001).
  • [ISSN] 0914-5087
  • [Journal-full-title] Journal of cardiology
  • [ISO-abbreviation] J Cardiol
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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10. Fujisawa S, Tanioka F, Matsuoka T, Ozawa T: CD5+ diffuse large B-cell lymphoma with c-myc/IgH rearrangement presenting as primary effusion lymphoma. Int J Hematol; 2005 May;81(4):315-8
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  • [Title] CD5+ diffuse large B-cell lymphoma with c-myc/IgH rearrangement presenting as primary effusion lymphoma.
  • We report an instructive case of diffuse large B-cell lymphoma presenting as acute heart failure.
  • A computed tomographic scan of the chest and abdomen showed pericardial effusion, but there was no evidence of tumor masses, lymph node enlargement, or hepatosplenomegaly.
  • During the chemotherapy, increased lactate dehydrogenase and pleural effusion appeared.
  • The tumor cells in the effusion showed positivity for CD5, CD19, CD20, kappa chain, and Bcl-2 and negativity for CD10 and CD23.
  • The response to chemotherapy was very poor, and the patient died 4 months after the diagnosis.
  • A spectrum of the symptoms of CD5+ lymphoma encompasses pericardial effusion and also can accompany c-myc/IgH rearrangement.
  • [MeSH-major] Gene Rearrangement. Lymphoma, B-Cell / complications. Lymphoma, B-Cell / genetics. Lymphoma, Large B-Cell, Diffuse / complications. Lymphoma, Large B-Cell, Diffuse / genetics. Pericardial Effusion / etiology. Pleural Effusion / etiology

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  • (PMID = 15914362.001).
  • [ISSN] 0925-5710
  • [Journal-full-title] International journal of hematology
  • [ISO-abbreviation] Int. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD5; 0 / Immunoglobulins
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11. Won JH, Han SH, Bae SB, Kim CK, Lee NS, Lee KT, Park SK, Hong DS, Lee DW, Park HS: Successful eradication of relapsed primary effusion lymphoma with high-dose chemotherapy and autologous stem cell transplantation in a patient seronegative for human immunodeficiency virus. Int J Hematol; 2006 May;83(4):328-30
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  • [Title] Successful eradication of relapsed primary effusion lymphoma with high-dose chemotherapy and autologous stem cell transplantation in a patient seronegative for human immunodeficiency virus.
  • Primary effusion lymphoma (PEL) is a recently recognized disease that occurs most often in immunosuppressed patients, either with human immunodeficiency virus (HIV) or in the posttransplantation setting, and it occasionally occurs in nonimmunosuppressed patients.
  • PEL rarely responds to systemic chemotherapy, and the prognosis is poor, with a median survival time of less than 6 months for most cohorts.
  • A standard treatment for PEL has not yet been identified.
  • We describe a patient with HIV-seronegative PEL who relapsed after combination chemotherapy and then underwent successful treatment with high-dose chemotherapy (HDC) and autologous stem cell transplantation (ASCT).
  • The treatment was well tolerated, and the patient has been in remission for 12 months after HDC and ASCT.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Heart Neoplasms / therapy. Lymphoma / therapy. Pericardial Effusion / therapy. Stem Cell Transplantation


12. Gowda RM, Khan IA: Clinical perspectives of primary cardiac lymphoma. Angiology; 2003 Sep-Oct;54(5):599-604
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical perspectives of primary cardiac lymphoma.
  • Primary cardiac lymphoma is a very rare malignancy, which is typically of a non-Hodgkin type, and involves only the heart and pericardium with no or minimal evidence of extracardiac involvement.
  • Primary cardiac lymphoma account for about 1% of the primary cardiac tumors and 0.5% of the extranodal lymphomas.
  • On the other hand, disseminated lymphoma with cardiac involvement can occur in up to 20% of patients with lymphoma.
  • About 80% of cases of the primary cardiac lymphoma in immunocompetent hosts are of diffuse B-cell lymphoma, and in patients with immunodeficiency states, small noncleaved or immunoblastic lymphomas are more frequent.
  • Clinical presentation is heterogeneous and is generally related to the site of involvement in the heart.
  • The diagnosis is suspected when patients present with a cardiac mass or an unexplained refractory pericardial effusion.
  • A thorough workup should include transthoracic and transesophageal echocardiography, computed tomography, and magnetic resonance imaging.
  • Diagnosis is confirmed by cytology of the serous fluid from pericardial or pleural effusion or biopsy of the pericardial mass or endomyocardial tissue.
  • Chemotherapy has been used alone or combined with radiotherapy.
  • Combination of chemotherapy and radiation therapy is considered as the treatment of choice.
  • The survival is generally less than a month without treatment but has been prolonged up to 5 years with palliative treatments in selected cases.
  • [MeSH-major] Heart Neoplasms. Lymphoma

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  • (PMID = 14565636.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 62
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13. Yukiiri K, Mizushige K, Ueda T, Kohno M: Second primary cardiac B-cell lymphoma after radiation therapy and chemotherapy--a case report. Angiology; 2001 Aug;52(8):563-5
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  • [Title] Second primary cardiac B-cell lymphoma after radiation therapy and chemotherapy--a case report.
  • A 76-year-old man was found to have esophageal squamous cell carcinoma and had been treated with radiational therapy and chemotherapy.
  • An echocardiographic examination revealed a mass lesion in the pericardium with pericardial effusion behind the left ventricular posterior wall, which was near the site of the original esophageal cancer.
  • No findings indicated a recurrence of the esophageal cancer; cytologic studies showed malignant lymphoma cells of B-cell origin.
  • A second primary cancer of some organs including blood cells might be induced by the carcinogenic effects of ionizing radiation or chemotherapeutic agents.
  • This is the first case of second primary cardiac B-cell lymphoma after combination therapy.
  • [MeSH-major] Carcinoma, Squamous Cell / therapy. Esophageal Neoplasms / therapy. Heart Neoplasms / diagnosis. Lymphoma, B-Cell / diagnosis. Neoplasms, Second Primary / diagnosis
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy, Needle. Cisplatin / administration & dosage. Coronary Angiography. Echocardiography, Transesophageal. Esophagoscopy. Fluorouracil / administration & dosage. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Pericardial Effusion / pathology. Radiotherapy Dosage

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  • (PMID = 11512697.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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14. Rolla G, Bertero MT, Pastena G, Tartaglia N, Corradi F, Casabona R, Motta M, Caligaris-Cappio F: Primary lymphoma of the heart. A case report and review of the literature. Leuk Res; 2002 Jan;26(1):117-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary lymphoma of the heart. A case report and review of the literature.
  • Primary cardiac lymphoma (PCL) is a rare and usually fatal neoplasm, which may cause syncope, arrhythmia, heart failure and pericardial effusion as presenting clinical complaints.
  • The patient was investigated because of pericardial effusion and diagnosis of diffuse large B-cell lymphoma was obtained by open-chest biopsy of the heart.
  • Fatal ventricular arrhythmia developed the day after the first course of chemotherapy.
  • While chemotherapy is the only effective treatment of PCL, early post-chemotherapy phase should be considered critical in patients with PCL, as suggested by other reported fatal complications in this period.
  • [MeSH-major] Heart Neoplasms / pathology. Lymphoma, B-Cell / pathology
  • [MeSH-minor] Aged. Arrhythmias, Cardiac / complications. Arrhythmias, Cardiac / therapy. Humans. Male

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  • (PMID = 11734310.001).
  • [ISSN] 0145-2126
  • [Journal-full-title] Leukemia research
  • [ISO-abbreviation] Leuk. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 13
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15. Chiba Y, Oka K, Saito H, Nagayama R, Murata M, Mori N: Primary cardiac B-cell lymphoma presented as heart tamponade and atrioventricular block: a case report. Acta Cytol; 2010 Jan-Feb;54(1):79-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac B-cell lymphoma presented as heart tamponade and atrioventricular block: a case report.
  • BACKGROUND: Primay cardiac lymphoma is rare, and its diagnosis is not determined until autopsy.
  • CASE: A 49-year-old man presented with heart tamponade and atrioventricular block.
  • Bloody pericardiac effusion showed a monotonous proliferation of atypical large mononuclear cells, which demonstrated a lambda light-chain monoclonality by the fluorescence-activated cell-sorter method and clonal rearrangement bands by Southern blot analysis of the IgH gene.
  • Transvenous biopsy excised from the right atrial tumor was diagnosed as diffuse large B-cell lymphoma.
  • He underwent chemotherapy and permanent pacemaker implantation and is alive and well.
  • CONCLUSION: Liquid cytology of cardiac effusion was very useful for rapid diagnosis, leading to a better prognosis.
  • [MeSH-major] Atrioventricular Block / diagnosis. Cardiac Tamponade / diagnosis. Heart Neoplasms / diagnosis. Lymphoma, B-Cell / diagnosis. Pericardial Effusion / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Prognosis

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  • (PMID = 20306995.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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16. Maeder M, Spieler P, Krapf R, Diethelm M: Cytologically malignant lymphoid pericardial effusion with benign clinical outcome. Swiss Med Wkly; 2005 Jun 25;135(25-26):377-81
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  • [Title] Cytologically malignant lymphoid pericardial effusion with benign clinical outcome.
  • BACKGROUND: Isolated malignant pericardial effusion is a manifestation of primary cardiac lymphoma (PCL) and primary effusion lymphoma (PEL), rare types of non-Hodgkin's lymphoma (NHL).
  • The diagnosis is based on different cytological methods and analyses including DNA-image cytometry (ICM-DNA).
  • CASE DESCRIPTIONS AND RESULTS: A 75-year-old man and a 66-year-old woman underwent urgent pericardiocentesis for cardiac tamponade due to large pericardial effusion.
  • Although in neither of the two patients systemic chemotherapy was administered, both were free of cancer after a follow-up of ten and nine years respectively.
  • It seems that DNA-aneuploidy may be not absolutely specific for the detection of malignant lymphoid cells in pericardial fluid.
  • [MeSH-major] Heart Neoplasms / diagnosis. Lymphoma, Non-Hodgkin / diagnosis. Pericardial Effusion / diagnosis
  • [MeSH-minor] Aged. Aneuploidy. Cardiac Tamponade / etiology. Female. Humans. Image Cytometry. Male. Treatment Outcome

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  • (PMID = 16106328.001).
  • [ISSN] 1424-7860
  • [Journal-full-title] Swiss medical weekly
  • [ISO-abbreviation] Swiss Med Wkly
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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17. Antoniades L, Eftychiou C, Petrou PM, Bagatzounis A, Minas M: Primary cardiac lymphoma: case report and brief review of the literature. Echocardiography; 2009 Feb;26(2):214-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac lymphoma: case report and brief review of the literature.
  • Primary cardiac lymphoma is defined as a non-Hodgkin's lymphoma mainly located in the heart and/or the pericardium.
  • Common manifestations are pericardial effusion and heart failure.
  • Diagnosis is usually late and prognosis is poor.
  • We report a case of a patient with a large primary cardiac lymphoma who presented with chest pain and negative T-waves in electrocardiogram.
  • Tissue biopsy showed a high-grade B-cell diffuse lymphocytic lymphoma.
  • The patient was treated with chemotherapy and radiation with complete remission and prolonged survival.
  • [MeSH-major] Heart Neoplasms / diagnosis. Heart Neoplasms / therapy. Lymphoma, Large B-Cell, Diffuse / diagnosis. Lymphoma, Large B-Cell, Diffuse / therapy
  • [MeSH-minor] Aged. Chest Pain / etiology. Diagnosis, Differential. Echocardiography. Electrocardiography. Follow-Up Studies. Heart Atria / ultrasonography. Heart Ventricles / ultrasonography. Humans. Male. Rare Diseases. Remission Induction / methods

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  • (PMID = 19138175.001).
  • [ISSN] 1540-8175
  • [Journal-full-title] Echocardiography (Mount Kisco, N.Y.)
  • [ISO-abbreviation] Echocardiography
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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18. Saito T, Tamaru J, Kayao J, Kuzuu Y, Wakita H, Mikata A: Cytomorphologic diagnosis of malignant lymphoma arising in the heart: a case report. Acta Cytol; 2001 Nov-Dec;45(6):1043-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytomorphologic diagnosis of malignant lymphoma arising in the heart: a case report.
  • BACKGROUND: Primary malignant lymphoma of the heart is extremely rare.
  • We describe a case of malignant lymphoma involving predominantly the heart and pericardium and diagnosed by pericardiac effusion cytology antemortem.
  • Echocardiography revealed a low-echoic tumor mass close to the right ventricular wall and massive pericardiac effusion.
  • Diagnosis of diffuse large B-cell lymphoma was made by cytomorphologic examination and flow cytometry of the tumor cells obtained from the effusion.
  • Although chemotherapy was instituted immediately, the patient died of progressive heart failure.
  • Diffuse large B-cell lymphoma predominantly involving the intracardiovascular region was confirmed at autopsy.
  • CONCLUSION: From the experience in this case, we conclude that cytopathologic examination of sonographically guided aspiration of the cardiovascular region is very useful for antemortem diagnosis of primary malignant lymphoma of the heart.
  • [MeSH-major] Heart Neoplasms / diagnosis. Lymphoma, B-Cell / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Drug Therapy, Combination. Echocardiography. Fatal Outcome. Female. Flow Cytometry. Heart Failure / etiology. Heart Failure / pathology. Humans. Immunophenotyping. Pericardial Effusion / diagnosis. Prednisone / administration & dosage. Vincristine / administration & dosage

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  • (PMID = 11726101.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone
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19. Saotome M, Yoshitomi Y, Kojima S, Kuramochi M: Primary cardiac lymphoma--a case report. Angiology; 2002 Mar-Apr;53(2):239-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac lymphoma--a case report.
  • Primary cardiac lymphoma, which is very rare, is generally regarded to have a poor prognosis.
  • A case of a 69-year-old man with primary cardiac lymphoma diagnosed by antemortem examination is reported.
  • A computed tomography scan of the chest demonstrated a huge right atrial mass with invasion into the other chambers.
  • Cytologic analysis of pericardial effusion revealed diffuse large B-cell type non-Hodgkin malignant lymphoma.
  • The patient died on the 18th day of chemotherapy (cyclophosphamide, hydroxydaunomycin, oncovin, and prednisone) due to low-output syndrome and multiple organ failure.
  • Although prognosis of primary cardiac lymphoma remains poor, early diagnosis may improve the prognosis.
  • [MeSH-major] Heart Neoplasms / complications. Lymphoma / complications
  • [MeSH-minor] Aged. Autopsy. Diagnosis, Differential. Humans. Male. Postmortem Changes

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  • (PMID = 11952118.001).
  • [ISSN] 0003-3197
  • [Journal-full-title] Angiology
  • [ISO-abbreviation] Angiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Chalabreysse L, Berger F, Loire R, Devouassoux G, Cordier JF, Thivolet-Bejui F: Primary cardiac lymphoma in immunocompetent patients: a report of three cases and review of the literature. Virchows Arch; 2002 Nov;441(5):456-61

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary cardiac lymphoma in immunocompetent patients: a report of three cases and review of the literature.
  • Primary cardiac lymphoma is an extranodal non-Hodgkin's lymphoma exclusively located in the heart and/or pericardium, extremely rare in immunocompetent patients, and more frequent in immunodepressed patients.
  • We present 3 retrospectives cases of primary cardiac lymphoma in immunocompetent patients and review 35 cases reported in the literature.
  • Primary cardiac lymphoma presented with constitutional symptoms in two cases and superior vena caval syndrome in one case.
  • Diagnosis of a tumor mass was made in all cases by transthoracic echocardiography.
  • Primary cardiac lymphoma arose in the heart right chambers in two cases.
  • Histological diagnoses, obtained after thoracotomy, were diffuse large B-cell lymphoma in two cases, and Burkitt's lymphoma in one case.
  • All three cases received chemotherapy, combined with radiotherapy in one patient.
  • Of our patients, 2 are alive and asymptomatic 12 months and 33 months after diagnosis.
  • In conclusion, diagnosis of primary cardiac lymphoma is difficult due to non-specific clinical manifestations and should be considered in patients with a cardiac mass sometimes with pericardial effusion.
  • The only effective treatment is chemotherapy, but prognosis remains poor.
  • [MeSH-major] Burkitt Lymphoma / pathology. Heart Neoplasms / pathology. Immunocompetence. Lymphoma, Large B-Cell, Diffuse / pathology

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  • (PMID = 12447675.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 42
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21. Nakagawa H: [A case of primary cardiac lymphoma complicated by idiopathic thrombocytopenic purpura]. Nihon Kokyuki Gakkai Zasshi; 2002 Mar;40(3):265-9
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  • [Title] [A case of primary cardiac lymphoma complicated by idiopathic thrombocytopenic purpura].
  • An 80-year-old woman was admitted to our hospital for investigation of left pleural effusion.
  • A computed tomography (CT) scan of the chest revealed a tumor mass in the right anterior ventricular wall.
  • Scintigraphy with 67Ga citrate showed tracer accumulation in the heart and no accumulation in other regions.
  • The cytology of the pleural effusion was consistent with non-Hodgkin's lymphoma.
  • Primary cardiac lymphoma (PCL) was diagnosed.
  • The tumor mass showed a marked reduction in size after 3 cycles of chemotherapy, but thrombocytopenia unrelated to bone marrow failure appeared.
  • Idiopathic thrombocytopenic purpura (ITP) was suspected and prednisolone therapy was begun, and ultimately brought about a partial remission.
  • Autoimmune disorders are occasionally associated with malignant lymphoma.
  • [MeSH-major] Heart Neoplasms / complications. Lymphoma, Non-Hodgkin / complications. Purpura, Thrombocytopenic, Idiopathic / etiology

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  • (PMID = 11974905.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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22. Fuzellier JF, Saade YA, Torossian PF, Baehrel B: [Primary cardiac lymphoma: diagnosis and treatment. Report of 6 cases and review of the literature]. Arch Mal Coeur Vaiss; 2005 Sep;98(9):875-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary cardiac lymphoma: diagnosis and treatment. Report of 6 cases and review of the literature].
  • Primary cardiac lymphoma (PCL) is the rarest primary cardiac tumour and carries a poor prognosis.
  • Early diagnosis, often difficult, to introduce appropriate treatment as soon as possible, seems to have a positive impact on prognosis.
  • The presentations were tamponade (N= 2), right heart failure (N= 1), general ill health (N= 3).
  • A PCL was suspected on echocardiography and thoracic CT scan showing tumour invading the right heart chambers in all cases.
  • The diagnosis of PCL was confirmed by surgical biopsy in 5 patients and by endomyocardial biopsy in 1 patient.
  • A diffuse large cell type B lymphoma was found in 5 patients and an anaplastic lymphoma in 1 patient.
  • One patient died of right heart failure 4 days after diagnosis and before starting chemotherapy.
  • All the other patients received chemotherapy.
  • The other three patients had several courses of chemotherapy: there are two survivors 17, 5 months later and one patient died 62 months after diagnosis.
  • The diagnosis of PCL should be suspected in patients with a cardiac tumour associated or not with pericardial effusion.
  • Early, appropriate chemotherapy seems to have a positive impact on the prognosis, justifying aggressive approaches to obtain a rapid histological diagnosis.
  • [MeSH-major] Heart Neoplasms / diagnosis. Lymphoma / diagnosis
  • [MeSH-minor] Adult. Aged. Antineoplastic Agents / therapeutic use. Cardiac Tamponade / etiology. Female. Heart Failure / etiology. Humans. Male. Middle Aged

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  • (PMID = 16231573.001).
  • [ISSN] 0003-9683
  • [Journal-full-title] Archives des maladies du coeur et des vaisseaux
  • [ISO-abbreviation] Arch Mal Coeur Vaiss
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 35
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23. Houchaymi Z, Helou S, Ballout J: [Pericardial tamponade and third-degree atrioventricular block revealing a primary cardiac lymphoma]. Rev Med Interne; 2010 Nov;31(11):e4-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pericardial tamponade and third-degree atrioventricular block revealing a primary cardiac lymphoma].
  • Secondary and primary cardiac tumors are rare, and primary cardiac lymphoma are exceptional.
  • Analysis of the pericardial fluid and tissue was not contributive.
  • À transvenous biopsy of the cardiac tumour revealed non-Hodgkin large B-cell lymphoma (CD45+ CD20+ CD3-BCl2+).
  • Therapy is based on chemotherapy.
  • However, prognosis remains poor for this type of tumor commonly revealed by a pericardial effusion.

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  • [Copyright] Copyright © 2010 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
  • (PMID = 20605278.001).
  • [ISSN] 1768-3122
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone
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24. Porcar Ramells C, Clemente González C, García Parés D, Guardia Sánchez R, Pérez Ayuso MJ, García-Bragado Dalmau F: [Primary cardiac lymphoma: cytological diagnosis and treatment with response to polychemotherapy and hematopoietic precursor autotransplant. Presentation of a case a review of the literature]. An Med Interna; 2002 Jun;19(6):305-9
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  • [Title] [Primary cardiac lymphoma: cytological diagnosis and treatment with response to polychemotherapy and hematopoietic precursor autotransplant. Presentation of a case a review of the literature].
  • [Transliterated title] Linfoma cardiaco primario: diagnóstico citológico y tratamiento con respuesta a poliquimioterapia y a autotrasplante de precursores hematopoyéticos. Presentación de un caso y revisión de la literatura.
  • The primary cardiac lymphoma (PCL) is an extremely infrequent tumor suffered by immunocompetent patients with a difficult diagnosis and slow progress leading to a serious prognosis and few therapeutically possibilities.
  • It's a primary-cardiac non-Hodgkin's lymphoma (NHL) in a patient of 46-year-old, immunocompetent, who started with a congestive heart failure and atrial flutter.
  • Some examinations were carried out such as a transesophageal echocardiography (TEE), a computed tomography (TC) and a magnetic resonance imaging (MRI) and an intracardiac tumor placed in the interauricular septum was detected.
  • The diagnosis was based on a pleural fluid cytological examination.
  • It was decided to follow a chemotherapy treatment and the autologous peripheral blood stem cells transplantation was carried out.
  • The patient remains in full remission thirty-six months after diagnosis and twenty-nine months after the autotransplant.
  • Our clinical experience indicated that an early and accurate diagnosis combined with the appropriate and aggressive antilymphoma therapy can thus help in obtaining a long survival in patients with PCL.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Neoplasms / diagnosis. Heart Septum. Hematopoietic Stem Cell Transplantation. Lymphoma, Large B-Cell, Diffuse / diagnosis
  • [MeSH-minor] Atrial Flutter / etiology. Carmustine / administration & dosage. Cyclophosphamide / administration & dosage. Cytarabine / administration & dosage. Doxorubicin / administration & dosage. Echocardiography, Transesophageal. Etoposide / administration & dosage. Heart Failure / etiology. Humans. Hydrocortisone / administration & dosage. Immunocompetence. Injections, Spinal. Magnetic Resonance Imaging. Male. Melphalan / administration & dosage. Methotrexate / administration & dosage. Middle Aged. Pleural Effusion / etiology. Prednisone / administration & dosage. Remission Induction. Tomography, X-Ray Computed. Transplantation Conditioning. Transplantation, Autologous. Vincristine / administration & dosage

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  • (PMID = 12152391.001).
  • [ISSN] 0212-7199
  • [Journal-full-title] Anales de medicina interna (Madrid, Spain : 1984)
  • [ISO-abbreviation] An Med Interna
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; Q41OR9510P / Melphalan; U68WG3173Y / Carmustine; VB0R961HZT / Prednisone; WI4X0X7BPJ / Hydrocortisone; YL5FZ2Y5U1 / Methotrexate; BEAM regimen; CHOP protocol
  • [Number-of-references] 56
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25. Mioulet D, Braem L, Heno P, Paule P, Peloni JM, Bonnet D, Fourcade L: [Cardiac extension of a non-Hodgkin lymphoma revealed by an atrial flutter]. Ann Cardiol Angeiol (Paris); 2009 Apr;58(2):117-21
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  • [Title] [Cardiac extension of a non-Hodgkin lymphoma revealed by an atrial flutter].
  • Primary or secondary cardiac lymphomas are not frequent.
  • Their clinical expression is unusual and the diagnosis is rarely made during the patient's life.
  • Our case report, which is a slow atrial flutter with a pericardial effusion, is an uncommon discovery mode for a malignant lymphoma.
  • Their diagnosis and the mechanism of the arythmia were allowed by non-invasive cardiac imagery (transesophageal echography and magnetic resonance imaging), which showed a tumour-like infiltration of the right atrium, of the right ventricle posterior wall, and of the atrioventricular junction.
  • The diagnosis of a high grade B cell malignant non-hodgkin lymphoma, involving the bone marrow, the liver and the kidneys was made by biopsies of lymph nodes, histological analysis of the bone marrow, and a body CT scan.
  • Throughout the first chemotherapy sequence, we observed a spontaneous return to a sinusal rhythm, and the cardiac MRI showed a regression of the myocardial infiltration and of the pericardial effusion; moreover, the patient's state improved and the peripheral lymph nodes shrank back to a normal size.
  • However, the patient passed away, due to neurological complications 13 months after the diagnosis of lymphoma, without recurrence of cardiac involvement.
  • [MeSH-major] Atrial Flutter / etiology. Heart Neoplasms / complications. Lymphoma, B-Cell / complications

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  • (PMID = 18657797.001).
  • [ISSN] 1768-3181
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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26. Rafajlovski S, Tatić V, Ilić S, Kanjuh V: [Frequency of metastatic tumors in the heart]. Vojnosanit Pregl; 2005 Dec;62(12):915-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Frequency of metastatic tumors in the heart].
  • INTRODUCTION: Secondary or metastatic tumors in the heart occur more frequently than primary ones, and, according to the published series, their frequency found in autopsic material ranges from 1.6% to 20.6%.
  • Metastatic tumors in the heart are rarely clinically symptomatic, and, therefore, they are rarely diagnosed within the lifetime.
  • The aim of this study was to analyze the frequency of metastatic tumors of the heart, their primary localization, as well as the localization of the metastases found in the autopsic material within the period 1972-2004.
  • METHODS: During the autopsy of the patients died of metastatic tumors, we microscopically and macroscopically analyzed all the organs and tissues to determine the metastases of primary tumors in other organs, especially in the heart and pericardium.
  • In 2 928 (25.6%) out of 11 403 autopsies, the presence of malignant tumor was diagnosed, and in 79 (2.7%) of these cases, metastasis of the heart was found out.
  • Only in 5 of the cases, the presence of metastasis in the heart was diagnosed during the lifetime.
  • The most frequent metastases in the heart were caused by pulmonary carcinoma (18 cases), leukemia and malignant lymphoma (8 cases, each), then pancreatic and breast carcinoma, while the metastases of other carcinomas were rather rare.
  • CONCLUSION: Metastatic tumors of the heart are rather rare, and rarely clinically symptomatic, and, thus, rarely diagnosed during life.
  • The methods of choice for the diagnosis of the metastasis in the heart are echocardiography, computerized tomography, magnetic resonance imaging, cytological analysis of the pericardial effusion and biopsy.
  • The treatment includes surgery, chemotherapy and radiotherapy.
  • [MeSH-major] Heart Neoplasms / secondary

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  • (PMID = 16375220.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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27. Boeckle E, Boesmueller C, Wiesmayr S, Mark W, Rieger M, Tabarelli D, Graziadei I, Hoefer D, Antretter H, Stelzmueller I, Krugmann J, Zangerle R, Huemer H, Poelzl G, Margreiter R, Bonatti H: Kaposi sarcoma in solid organ transplant recipients: a single center report. Transplant Proc; 2005 May;37(4):1905-9
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Human herpes virus (HHV8) is associated with Castleman's disease, primary effusion lymphoma, and the Kaposi's sarcoma (KS).
  • Diagnosis of KS was based in all cases on histology.
  • The heart recipient developed a tumor on the planta pedis; one renal recipient, on both legs.
  • Treatment in all cases consisted of reduction in immunosuppression, together with surgery (n = 1), chemotherapy (n = 1), or irradiation (n = 2).
  • Nevertheless, awareness of KS is important for early diagnosis and optimal treatment.
  • [MeSH-major] Heart Transplantation / physiology. Kidney Transplantation / physiology. Liver Transplantation / physiology. Sarcoma, Kaposi / complications. Sarcoma, Kaposi / therapy
  • [MeSH-minor] Adult. Drug Therapy, Combination. Female. Humans. Immunosuppression / methods. Immunosuppressive Agents / therapeutic use. Male. Middle Aged. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Heart Transplantation.
  • MedlinePlus Health Information. consumer health - Kaposi's Sarcoma.
  • MedlinePlus Health Information. consumer health - Kidney Transplantation.
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  • (PMID = 15919500.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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