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1. He J, Makey D, Fojo T, Adams KT, Havekes B, Eisenhofer G, Sullivan P, Lai EW, Pacak K: Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma. Endocrine; 2009 Oct;36(2):189-93
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  • [Title] Successful chemotherapy of hepatic metastases in a case of succinate dehydrogenase subunit B-related paraganglioma.
  • Compared to other familial pheochromocytoma/paragangliomas (PHEO/PGLs), the succinate dehydrogenase subunit B (SDHB)-related PHEO/PGLs often present with aggressive and rapidly growing metastatic lesions.
  • Currently, there is no proven effective treatment for malignant PHEO/PGLs.
  • Here, we present a 35-year-old white man with primary malignant abdominal extra-adrenal 11 cm paraganglioma underwent surgical successful resection.
  • But 6 months later, he developed extensive bone, liver, and lymph nodes metastasis, which were demonstrated by computed tomography scan and the (18)F-fluorodeoxyglucose positron emission tomography.
  • However, his (123)I-metaiodobenzylguanidine scintigraphy was negative; therefore, the cyclophosphamide, vincristine, and dacarbazine (CVD) combination chemotherapy was initiated.
  • The combination chemotherapy was very effective showing 80% overall reduction in the liver lesions and 75% overall reduction in the retroperitoneal mass and adenopathy, and normalization of plasma catecholamine and metanephrine levels.
  • Here, we present an SDHB-related PHEO/PGL patient with extensive tumor burden, numerous organ lesions, and rapidly growing tumors, which responded extremely well to CVD therapy.
  • We conclude patients with SDHB-related PHEO/PGLs can be particularly sensitive to CVD chemotherapy and may have an excellent outcome if this therapy is used and continued on periodic basis.
  • The data in this patient also illustrate the importance of measuring plasma levels of DA and MTY to provide a more complete and accurate assessment of the biochemical response to therapy than provided by measurements restricted to other catecholamines and O-methylated metabolites.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Liver Neoplasms / drug therapy. Paraganglioma, Extra-Adrenal / drug therapy
  • [MeSH-minor] Adult. Combined Modality Therapy. Cyclophosphamide / therapeutic use. Dacarbazine / therapeutic use. Humans. Male. Succinate Dehydrogenase / genetics. Treatment Outcome. Vincristine / therapeutic use

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  • (PMID = 19618298.001).
  • [ISSN] 1559-0100
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / Z01 HD008735-08
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 7GR28W0FJI / Dacarbazine; 8N3DW7272P / Cyclophosphamide; EC 1.3.5.1 / SDHB protein, human; EC 1.3.99.1 / Succinate Dehydrogenase; CVD protocol
  • [Other-IDs] NLM/ NIHMS750174; NLM/ PMC4713025
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2. Huang KH, Chung SD, Chen SC, Chueh SC, Pu YS, Lai MK, Lin WC: Clinical and pathological data of 10 malignant pheochromocytomas: long-term follow up in a single institute. Int J Urol; 2007 Mar;14(3):181-5
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  • The diagnosis of pheochromocytoma was confirmed at surgery.
  • All patients had metastases in sites where chromaffin tissue was normally absent.
  • Extra-adrenal tumors occurred in four patients including paraganglioma tumors in three cases and bladder tumor in one case.
  • Histological characteristics were not helpful for diagnosis of malignancy and for prediction of prognosis.
  • Three patients received chemotherapy and one patient received combination therapy of high-dose (131)I-meta-iodobenzylguanidine ((131)I-MIBG) therapy and chemotherapy.
  • All patients achieved long-term survival except for two who died of metastasis 1.5 years and 2 years after diagnosis.
  • [MeSH-major] Adrenal Gland Neoplasms / pathology. Adrenal Gland Neoplasms / therapy. Adrenalectomy. Antineoplastic Agents / therapeutic use. Pheochromocytoma
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Neoplasms / diagnosis. Bone Neoplasms / secondary. Female. Follow-Up Studies. Humans. Liver Neoplasms / diagnosis. Liver Neoplasms / secondary. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Positron-Emission Tomography. Prognosis. Radiotherapy, Adjuvant. Retrospective Studies. Survival Rate. Time Factors. Tomography, X-Ray Computed. Urinary Bladder Neoplasms / diagnosis. Urinary Bladder Neoplasms / secondary

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  • (PMID = 17430251.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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3. Gómez Esteban JC, Boyero S, Fernández C, Sagasta A, Pérez T, Velasco F, Allue I, Lezcano E, Zarranz JJ: [Baroreflex failure after chemodectoma resection]. Neurologia; 2004 Oct;19(8):452-5
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  • [Title] [Baroreflex failure after chemodectoma resection].
  • [Transliterated title] Fallo barorreflejo tras intervención de un quemodectoma.
  • Baroreflex failure after chemodectoma resection We present a case of baroreflex failure secondary to a unilateral injury of the glossopharyngeal nerve.
  • The patient was operated for a left-sided chemodectoma in the carotid body.
  • The diagnosis was baroreflex failure secondary to unilateral injury of the glossopharyngeal nerve.
  • The case reported herein illustrates the fact that the presence of a bilateral injury is not essential for the occurrence of this disorder.
  • [MeSH-major] Baroreflex. Glossopharyngeal Nerve Injuries. Neurosurgical Procedures / adverse effects. Paraganglioma, Extra-Adrenal / surgery
  • [MeSH-minor] Aged. Angiography. Antihypertensive Agents / therapeutic use. Autonomic Nervous System Diseases / etiology. Blood Pressure / drug effects. Clonidine / pharmacology. Female. Humans. Hypertension / drug therapy

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  • (PMID = 15470587.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antihypertensive Agents; MN3L5RMN02 / Clonidine
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4. Kruijtzer CM, Beijnen JH, Swart M, Schellens JH: Successful treatment with paclitaxel of a patient with metastatic extra-adrenal pheochromocytoma (paraganglioma). A case report and review of the literature. Cancer Chemother Pharmacol; 2000;45(5):428-31
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  • [Title] Successful treatment with paclitaxel of a patient with metastatic extra-adrenal pheochromocytoma (paraganglioma). A case report and review of the literature.
  • This case report describes the history of a patient with an aggressive course of a metastatic extra-adrenal pheochromocytoma (paraganglioma) who received different combination chemotherapy regimens with no or short-lasting clinical benefit.
  • However, during treatment with single-agent paclitaxel, there was a significant clinical improvement, a partial biochemical response and a minor roentgenologic response, which was sustained for 1 year.
  • In this report we present this case and also review the literature on the chemotherapy used for this rare disease over the past 15 years.
  • To enable the activity of paclitaxel against this neoplasm to be determined, more patients need to be treated.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Paclitaxel / therapeutic use. Paraganglioma / drug therapy
  • [MeSH-minor] Adult. Humans. Male. Neoplasm Metastasis

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  • (PMID = 10803928.001).
  • [ISSN] 0344-5704
  • [Journal-full-title] Cancer chemotherapy and pharmacology
  • [ISO-abbreviation] Cancer Chemother. Pharmacol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] GERMANY
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
  • [Number-of-references] 21
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5. Pacheco-Ojeda L: Malignant carotid body tumors: report of three cases. Ann Otol Rhinol Laryngol; 2001 Jan;110(1):36-40

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  • The first was in a 40-year-old man who presented with pulmonary metastases 6 years after resection of a CBT.
  • He was treated with chemotherapy and interferon, but died with disseminated disease 2 years later.
  • This lesion was completely resected, and a shunt and reconstruction with a saphenous vein graft were performed.
  • Pathology revealed a malignant chemodectoma with invasion to 2 of the 5 lymph nodes removed.
  • Radiotherapy (50 Gy) was given after the operation.
  • She is well and free of disease 68 months after the resection.
  • On computed tomography, the tumor extended to the infratemporal fossa with no bone involvement.
  • The lesion was embolized with a 40% reduction in vascularity.
  • At surgical exploration, the tumor involved the sternocleidomastoid muscle and the lymph nodes at levels II and III, and the internal carotid artery could not be dissected free at the skull base, so only a partial resection was performed.
  • Current multidisciplinary treatments have been unsuccessful in controlling disseminated disease.
  • [MeSH-major] Carotid Body Tumor. Paraganglioma, Extra-Adrenal

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  • (PMID = 11201806.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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6. Kavakli K, Ozturk M, Ongoru O, Gürkök S, Genc O: Primary pulmonary paraganglioma with Hodgkin's lymphoma. Thorac Cardiovasc Surg; 2009 Sep;57(6):375-7
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  • [Title] Primary pulmonary paraganglioma with Hodgkin's lymphoma.
  • Extra-adrenal paragangliomas are uncommon tumors arising from neuroectodermal-derived paraganglionic tissue.
  • There are very few case reports on primary pulmonary paraganglioma in the literature.
  • We present the case of a 21-year-old man who was treated with chemotherapy for Hodgkin's lymphoma.
  • Only a partial response was noted so he underwent additional chemotherapy and involved field radiotherapy.
  • Subsequent bronchoscopic biopsy showed paraganglioma and the patient underwent a left lower lobectomy.
  • [MeSH-major] Hodgkin Disease / diagnosis. Lung Neoplasms / diagnosis. Paraganglioma, Extra-Adrenal / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols. Biopsy. Bronchoscopy. Chemotherapy, Adjuvant. Humans. Lymph Node Excision. Male. Pneumonectomy. Positron-Emission Tomography. Radiotherapy, Adjuvant. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • [Copyright] Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 19707986.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 7
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7. Miyauchi J, Kiyotani C, Shioda Y, Kumagai M, Honna T, Matsuoka K, Masaki H, Aiba M, Hata J, Tsunematsu Y: Unusual chromaffin cell differentiation of a neuroblastoma after chemotherapy and radiotherapy: report of an autopsy case with immunohistochemical evaluations. Am J Surg Pathol; 2004 Apr;28(4):548-53
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  • [Title] Unusual chromaffin cell differentiation of a neuroblastoma after chemotherapy and radiotherapy: report of an autopsy case with immunohistochemical evaluations.
  • Despite the fact that neuroblastomas most often arise from the adrenal medulla, chromaffin-cell differentiation in neuroblastomas is not widely recognized.
  • Tumor cells with a chromaffin-cell nature have only been detected using histochemical techniques in neuroblastoma cell lines or focal areas of certain in vivo tumors.
  • We describe a neuroblastoma that exhibited an unusual differentiation toward chromaffin cells in a patient that had been treated with surgery, intensive chemotherapy, and radiotherapy.
  • Although a biopsy specimen of the retroperitoneal primary tumor was extensively necrotic, possibly because of a previous chemotherapy regimen, surgically resected metastatic tumors of bilateral ovaries were viable and diagnosed as poorly differentiated neuroblastomas according to the International Neuroblastoma Pathology Classification system.
  • However, metastatic tumors of bilateral lungs examined at the time of autopsy exhibited histologic features similar to those of a pheochromocytoma/paraganglioma, and immunohistochemical examinations demonstrated that these tumors were composed of extra-adrenal chromaffin cells.
  • This case confirms that neuroblastomas in childhood can transform into pheochromocytoma/paraganglioma-like tumors under special conditions.
  • [MeSH-major] Chromaffin Cells. Neuroblastoma / pathology. Retroperitoneal Neoplasms / pathology
  • [MeSH-minor] Cell Differentiation. Child, Preschool. Combined Modality Therapy. Fatal Outcome. Female. Humans. Immunohistochemistry. Ovarian Neoplasms / secondary

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  • (PMID = 15087676.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Horenstein MG, Hitchcock TA, Tucker JA: Dual CD117 expression in gastrointestinal stromal tumor (GIST) and paraganglioma of Carney triad: a case report. Int J Surg Pathol; 2005 Jan;13(1):87-92
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  • [Title] Dual CD117 expression in gastrointestinal stromal tumor (GIST) and paraganglioma of Carney triad: a case report.
  • Carney triad is a rare syndrome, with only 20 complete cases reported.
  • We report a 36-year-old white woman with complete Carney triad, including metastatic gastric stromal tumor (GIST), pulmonary chondroma, and nonfunctioning extra-adrenal paraganglioma.
  • Immunohistochemistry was positive for CD34 and CD117 (c-kit) in the GIST, and positive for chromogranin and CD117 in the paraganglioma.
  • To our knowledge, this is the 21st complete Carney triad case reported and the first report of dual expression CD117 in both GIST and paraganglioma, a finding with intriguing pathogenetic implications related to the organization of the autonomic nervous system.
  • [MeSH-major] Chondroma / pathology. Gastrointestinal Stromal Tumors / pathology. Leiomyosarcoma / secondary. Lung Neoplasms / pathology. Paraganglioma, Extra-Adrenal / pathology. Proto-Oncogene Proteins c-kit / analysis
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Antineoplastic Agents / therapeutic use. Biomarkers, Tumor / analysis. Chromogranins / analysis. Drug Therapy. Female. Humans. Palliative Care. Syndrome

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  • (PMID = 15735861.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor; 0 / Chromogranins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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9. Plouin PF, Amar L, Lepoutre C: Phaeochromocytomas and functional paragangliomas: clinical management. Best Pract Res Clin Endocrinol Metab; 2010 Dec;24(6):933-41
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  • [Title] Phaeochromocytomas and functional paragangliomas: clinical management.
  • Phaeochromocytomas (PH) and functional paragangliomas (FPGL) are neoplasms of adrenal (PH) or extra-adrenal (FPGL) chromaffin tissue that synthesize catecholamines.
  • Catecholamines are converted into inactive metabolites, metanephrines, within the tumour and the diagnosis of PH/FPGL is therefore based on the quantification of plasma or urinary metanephrines.
  • The tumour can be located by computed tomography, magnetic resonance imaging and metaiodobenzylguanidine scintigraphy.
  • Patients with PH/FPGL should be followed up indefinitely as the disease may recur, particularly if they have inherited or extra-adrenal tumours.
  • Recurrences and malignancy are more frequent in cases with large or extra-adrenal tumours, and in SDHB mutation carriers.
  • Treatments for progressive malignant PH/FPGL include tumour debulking, metabolic radiotherapy, chemotherapy, and possibly tyrosine kinase inhibitors.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / therapy. Paraganglioma / diagnosis. Paraganglioma / therapy. Pheochromocytoma / diagnosis. Pheochromocytoma / therapy

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  • [Copyright] 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 21115162.001).
  • [ISSN] 1878-1594
  • [Journal-full-title] Best practice & research. Clinical endocrinology & metabolism
  • [ISO-abbreviation] Best Pract. Res. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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10. Sattar HA, Yang DL, Husain AN, Redleaf MI, Dayal VS: Multiple paragangliomata of the lungs and temporal bone. Ear Nose Throat J; 2008 Nov;87(11):E4-6
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  • [Title] Multiple paragangliomata of the lungs and temporal bone.
  • We report the case of a 71-year-old woman with multiple benign lung paragangliomata and a benign glomus jugulare paraganglioma in one temporal bone that mimicked a malignancy.
  • The patient's lung lesions did not regress with chemotherapy.
  • A finding of multiple lung paragangliomata should raise the suspicion of a multicentric rather than malignant tumor.
  • [MeSH-major] Lung Neoplasms / secondary. Paraganglioma, Extra-Adrenal / pathology. Skull Neoplasms / secondary. Temporal Bone / pathology

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  • (PMID = 19006054.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Lehmen JA, Babbel DM, Mikhitarian K, Choma TJ: Paraganglioma presenting as metastatic lesion in a cervical vertebra: a case report and review of the literature. Spine (Phila Pa 1976); 2010 Mar 1;35(5):E152-4
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  • [Title] Paraganglioma presenting as metastatic lesion in a cervical vertebra: a case report and review of the literature.
  • OBJECTIVE: To discuss the spinal presentation and treatment of paraganglioma, a rare tumor of the extra-adrenal paraganglia, derived from neural crest cells in sympathetic ganglions.
  • SUMMARY OF BACKGROUND DATA: Malignant paragangliomas are a very rare entity.
  • The diagnosis of malignant paraganglioma is made by local recurrence after total resection of the primary mass, or findings of distant metastases.
  • Our imaging workup, including plain radiograph, computerized tomography scan and MRI, revealed an intraosseous lesion at C6 with vertebral body destruction.
  • The histologic and immunohistochemical assays revealed a malignant paraganglioma.
  • RESULTS: Paragangliomas are often highly vascular tumors.
  • CONCLUSION: We report a rare case of malignant paraganglioma and discussed adjuvant treatments to consider for distant metastases, such as I-MIBG, conventional radiotherapy, and chemotherapy.
  • [MeSH-major] Cervical Vertebrae. Neck Pain / etiology. Paraganglioma / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Aged. Decompression, Surgical. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • (PMID = 20118832.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. Oleaga A, Goñi F: Pheochromocytoma: diagnostic and therapeutic update. Endocrinol Nutr; 2008 May;55(5):202-16

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  • [Title] Pheochromocytoma: diagnostic and therapeutic update.
  • Pheochromocytomas are catecholamine-secreting tumors that arise from chromaffin cells of the sympathetic nervous system.
  • In 80-85% of cases, these tumors are located in the adrenal medulla while the remainder is located in extra-adrenal chromaffin tissues (paragangliomas).
  • Pheochromocytomas account for 6.5% of incidentally discovered adrenal tumors.
  • These tumors may be sporadic or the result of several genetic diseases: multiple endocrine neoplasia type 2, von Hippel-Lindau syndrome, neurofibromatosis type 1, and familial paraganglioma associated with mutations in succinate dehydrogenase subunits.
  • Diagnosis of pheochromocytoma should first be established biochemically by measuring plasma free metanephrines and urinary fractionated metanephrines.
  • The radiological imaging tests of choice are computed tomography (CT) or magnetic resonance imaging (MRI).
  • Positron emission tomography (PET) with (18)F-F-fluorodopamine (F-DA) is useful in metastatic disease.
  • The treatment of choice is laparoscopic surgery after adequate alpha adrenergic blockade.
  • Chemotherapy is used for inoperable disease.
  • Prognosis is good except in malignant disease, in which 5-year survival is less than 50%.

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  • [Copyright] Copyright © 2008 Sociedad Española de Endocrinología y Nutrición. Published by Elsevier Espana. All rights reserved.
  • (PMID = 22967914.001).
  • [ISSN] 1575-0922
  • [Journal-full-title] Endocrinología y nutrición : órgano de la Sociedad Española de Endocrinología y Nutrición
  • [ISO-abbreviation] Endocrinol Nutr
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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13. Joynt KE, Moslehi JJ, Baughman KL: Paragangliomas: etiology, presentation, and management. Cardiol Rev; 2009 Jul-Aug;17(4):159-64
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  • [Title] Paragangliomas: etiology, presentation, and management.
  • Paragangliomas are catecholamine-secreting tumors arising from the chromaffin cells of the sympathetic ganglia, and are known as extra-adrenal pheochromocytomas.
  • Diagnosis is made by serum and urine analysis for catecholamines and metanephrines, and confirmed with imaging studies including computed tomography scanning, magnetic resonance imaging, or 123-I metaiodobenzylguanidine imaging.
  • Although the majority of paragangliomas are sporadic, a growing percentage of cases are found to be part of a familial genetic syndrome.
  • Genetic testing should be offered to patients diagnosed with paraganglioma, particularly in patients who are young, have multiple tumors, or have a family history of malignancy.
  • Management of paraganglioma is predicated on surgical resection, and careful perioperative management with alpha- and beta-adrenergic blockade is imperative for optimal outcomes.
  • The majority of these tumors are benign, but for patients with malignant disease, chemotherapy, and radiation therapy may provide modest benefit.
  • Long-term follow-up is essential, as paragangliomas can recur many years after initial diagnosis.
  • Ongoing research into the genetic underpinnings of this tumor may allow for more targeted molecular therapies in the future.
  • [MeSH-major] Adrenal Gland Neoplasms / therapy. Paraganglioma, Extra-Adrenal / therapy. Pheochromocytoma / therapy

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  • (PMID = 19525677.001).
  • [ISSN] 1538-4683
  • [Journal-full-title] Cardiology in review
  • [ISO-abbreviation] Cardiol Rev
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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14. Sawhney SA, Chapman AD, Carney JA, Gomersall LN, Dempsey OJ: Incomplete Carney triad--a review of two cases. QJM; 2009 Sep;102(9):649-53
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  • 'Carney's triad' characteristically includes multifocal pulmonary chondroma, gastric stromal sarcoma and extra-adrenal paraganglioma.
  • [MeSH-major] Chondroma / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Paraganglioma, Extra-Adrenal / diagnosis
  • [MeSH-minor] Adult. Anti-Bacterial Agents / therapeutic use. Antineoplastic Agents / therapeutic use. Benzamides. Bronchial Diseases / drug therapy. Bronchial Diseases / etiology. Female. Humans. Imatinib Mesylate. Neoplasms, Multiple Primary / diagnosis. Piperazines / therapeutic use. Pyrimidines / therapeutic use. Tomography, X-Ray Computed

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  • (PMID = 19561114.001).
  • [ISSN] 1460-2393
  • [Journal-full-title] QJM : monthly journal of the Association of Physicians
  • [ISO-abbreviation] QJM
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
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15. Brown K, Ratner M, Stoll M: Pheochromocytoma unmasked by imipramine in an 8-year-old girl. Pediatr Emerg Care; 2003 Jun;19(3):174-7
Hazardous Substances Data Bank. PHENOXYBENZAMINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Hypertension / etiology. Imipramine / pharmacology. Para-Aortic Bodies / pathology. Paraganglioma, Extra-Adrenal / diagnosis. Pheochromocytoma / diagnosis. Tachycardia / etiology
  • [MeSH-minor] Catecholamines / blood. Catecholamines / urine. Child. Emergencies. Enuresis / drug therapy. Female. Heart Murmurs. Humans. Hypertrophy, Left Ventricular / etiology. Nitroprusside / therapeutic use. Phenoxybenzamine / therapeutic use. Remission Induction. Sweating

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  • (PMID = 12813305.001).
  • [ISSN] 1535-1815
  • [Journal-full-title] Pediatric emergency care
  • [ISO-abbreviation] Pediatr Emerg Care
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Catecholamines; 0TTZ664R7Z / Phenoxybenzamine; 169D1260KM / Nitroprusside; OGG85SX4E4 / Imipramine
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