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Items 1 to 27 of about 27
1. Azarpira N, Torabineghad S, Rakei M: Brain tumor as an unusual presentation of posttransplant lymphoproliferative disorder. Exp Clin Transplant; 2009 Mar;7(1):58-61
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  • [Title] Brain tumor as an unusual presentation of posttransplant lymphoproliferative disorder.
  • OBJECTIVES: Posttransplant lymphoproliferative disorder following solid organ transplant is a lifethreatening form of posttransplant malignancy.
  • Its occurrence is typically associated with Epstein-Barr virus and profound immunosuppressive therapy.
  • We describe a case of posttransplant lymphoproliferative disorder in the brain parenchyma, 4 years after renal transplant.
  • A tumor in the right occipitoparietal lobe was detected by magnetic resonance imaging and excised.
  • Immunohistochemical testing of the tumor revealed B-cell marker and Epstein-Barr virus.
  • After surgery, the dosage of immunosuppressive drugs was reduced, and the patient was treated with chemotherapy and radiotherapy.
  • Our patient is well after treatment.
  • CONCLUSIONS: Reduction in immunosuppressive therapy is an important component of treatment for Epstein-Barr virus-positive posttransplant lymphoproliferative disorder and may lead to remission in early disease.
  • If reduced immunosuppression fails to control early disease, cytotoxic chemotherapy, surgery and radiotherapy, antiviral therapies, and cell-based therapies are other options for treatment.
  • [MeSH-major] Brain Neoplasms / virology. Epstein-Barr Virus Infections / complications. Immunosuppressive Agents / adverse effects. Kidney Transplantation / adverse effects. Lymphoproliferative Disorders / virology. Occipital Lobe / virology. Parietal Lobe / virology
  • [MeSH-minor] Chemotherapy, Adjuvant. Cranial Irradiation. Craniotomy. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Radiotherapy, Adjuvant. Treatment Outcome. Young Adult

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  • (PMID = 19364315.001).
  • [ISSN] 1304-0855
  • [Journal-full-title] Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation
  • [ISO-abbreviation] Exp Clin Transplant
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Immunosuppressive Agents
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2. Watanabe T, Fuse T, Umezu M, Yamamoto M, Demura K, Niwa Y: Radiation-induced osteosarcoma 16 years after surgery and radiation for glioma--case report. Neurol Med Chir (Tokyo); 2006 Jan;46(1):51-4
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  • A 35-year-old man developed osteosarcoma of the left parietal and occipital bones 16 years after radiotherapy for glioma in the right occipital lobe.
  • Radiotherapy of the primary neoplasm used 50 Gy administered to a localized field through two lateral ports.
  • The secondary neoplasm arose contralateral to the primary lesion but within the irradiated field.
  • The tumor had a multilocular cyst with considerable intracranial extension, and symptoms of elevated intracranial pressure were prominent early in the course.
  • After a short-lived initial remission following surgical intervention and chemotherapy, the patient deteriorated because of tumor recurrence and died 18 months after the diagnosis.
  • Radiation-induced osteosarcoma is a well-known but rare complication of radiotherapy for brain neoplasms with a poor prognosis.
  • [MeSH-major] Brain Neoplasms / radiotherapy. Glioma / radiotherapy. Neoplasms, Radiation-Induced / etiology. Occipital Bone. Osteosarcoma / etiology. Parietal Bone. Skull Neoplasms / etiology
  • [MeSH-minor] Adult. Humans. Male. Radiotherapy / adverse effects. Time Factors

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  • (PMID = 16434828.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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3. Terada T: Small cell carcinoma of the brain without extracranial involvement by serial CT, MRI and PET. Int J Clin Exp Pathol; 2010;3(3):323-7
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  • [Title] Small cell carcinoma of the brain without extracranial involvement by serial CT, MRI and PET.
  • The author reports herein a case of small cell carcinoma of the brain without extracranial tumors by serial imaging modalities.
  • Brain CT and MRI revealed a solitary cystic tumor (5 x 6 x 7 cm) in the left occipital lobe.
  • Preoperative diagnosis was a primary or metastatic brain tumor.
  • Pathologically, the tumor was small cell carcinoma positive for four types of pancytokeratins, cytokeratin (CK) 7, CK 18, thyroid transcriptional factor-1 (TTF-1), CD56, chromogranin, synaptophysin, neuron-specific enolase, p53 protein, KIT, PDGFRA, and Ki-67 antigen (labeling = 100%).
  • The patient was treated with radiation and cisplatin-based chemotherapy, and no tumors were found seven months after the operation.
  • The present case suggests that there are small cell carcinomas with a solitary brain metastasis without a radiologically detected primary site.
  • In the present case, primary small cell brain carcinoma cannot be excluded completely, although such a case has not been reported in the literature.
  • [MeSH-major] Brain Neoplasms / radiography. Brain Neoplasms / radionuclide imaging. Carcinoma, Small Cell / radiography. Carcinoma, Small Cell / radionuclide imaging
  • [MeSH-minor] Aged. Brain / pathology. Brain / radiography. Brain / radionuclide imaging. Combined Modality Therapy. Drug Therapy. Humans. Magnetic Resonance Imaging. Male. Positron-Emission Tomography. Radiotherapy. Tomography, X-Ray Computed

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  • (PMID = 20224732.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2836511
  • [Keywords] NOTNLM ; Brain / histopathology / immunohistochemistry / small cell carcinoma
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4. Isaka T, Maruno M, Suzuki T, Sato M, Yoshimine T: Skull metastases from atypical pulmonary carcinoid tumor in a 19-year-old man. Neurol Med Chir (Tokyo); 2006 Dec;46(12):609-13
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  • [Title] Skull metastases from atypical pulmonary carcinoid tumor in a 19-year-old man.
  • A 19-year-old man presented with a rare skull metastasis from atypical pulmonary carcinoid tumor (APCT) manifesting as headache, diplopia, and cough.
  • Head magnetic resonance imaging showed a skull base tumor extending from the posterior clinoid process to the clivus, and calvarial tumors in the right temporal and occipital bones.
  • Chest and abdominal computed tomography showed a round tumor, 4 cm in diameter, in the lower lobe of the right lung and multiple small tumors in the liver.
  • Surgery for the calvarial tumor in the right temporal bone was performed on June 27, 2003.
  • The histological diagnosis was skull metastasis of neuroendocrine tumor.
  • Partial resection of the right lower lobe was performed for the lung tumor on August 22, 2003.
  • The histological diagnosis was atypical carcinoid tumor.
  • Subsequent adjuvant systematic chemotherapy was performed.
  • We must consider APCT in the differential diagnosis of pulmonary tumors in adolescents, and perform follow-up observation or treatment, including surgery, if APCT is suspected.
  • [MeSH-major] Carcinoid Tumor / secondary. Lung Neoplasms / pathology. Skull Neoplasms / secondary

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  • (PMID = 17185889.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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5. Han X, Dong Y, Sun K, Lu Y: A huge occipital osteoblastoma accompanied with aneurysmal bone cyst in the posterior cranial fossa. Clin Neurol Neurosurg; 2008 Mar;110(3):282-5
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  • [Title] A huge occipital osteoblastoma accompanied with aneurysmal bone cyst in the posterior cranial fossa.
  • Osteoblastoma is an infrequent benign tumor and skull involvement is extremely rare.
  • The occipital bone is much less frequently involved.
  • We report an unusual case of a huge occipital osteoblastoma with aneurysmal bone cyst in the posterior cranial fossa of a 20-year-old young man.
  • MRI scan and CT three-dimensional reconstruction revealed that the tumor (approximately 8.5 cm x 6 cm x 5 cm) occupied nearly half volume of the posterior cranial fossa.
  • The cerebellum, the forth ventricle and brain stem were compressed remarkably and hydrocephalus was noted.
  • The tumor mass was multiloculated cystic and highly vascular.
  • Our case confirms the findings of previous investigators that if osteoblastoma is removed completely, no recurrence is expected even without adjuvant irradiation and chemotherapy.
  • [MeSH-major] Bone Cysts, Aneurysmal / pathology. Brain Neoplasms / pathology. Occipital Lobe. Osteoblastoma / pathology
  • [MeSH-minor] Aged. Brain / pathology. Cranial Fossa, Anterior / pathology. Cranial Fossa, Anterior / surgery. Humans. Magnetic Resonance Imaging. Male. Neurosurgical Procedures. Osteoblasts / pathology. Tomography, X-Ray Computed

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  • (PMID = 18055104.001).
  • [ISSN] 0303-8467
  • [Journal-full-title] Clinical neurology and neurosurgery
  • [ISO-abbreviation] Clin Neurol Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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6. Shibuya T, Osada T, Kodani T, Hojo M, Saito H, Ueyama H, Kato J, Nagahara A, Otaka M, Ogihara T, Nagao K, Fujime M, Watanabe S: Gastrointestinal hemorrhage as the first manifestation of metastatic extragonadal choriocarcinoma. Intern Med; 2009;48(7):551-4
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  • Based on these results, our diagnosis was extragonadal retroperitoneal germ cell tumor with gastric metastasis.
  • [MeSH-major] Choriocarcinoma / secondary. Gastrointestinal Hemorrhage / etiology. Retroperitoneal Neoplasms / diagnosis. Stomach Neoplasms / secondary
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / blood. Bleomycin / administration & dosage. Chorionic Gonadotropin / blood. Chorionic Gonadotropin, beta Subunit, Human / blood. Cisplatin / administration & dosage. Combined Modality Therapy. Etoposide / administration & dosage. Gastroscopy. Humans. Ifosfamide / administration & dosage. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Male. Occipital Lobe / pathology. Occipital Lobe / surgery. Remission Induction. Supratentorial Neoplasms / drug therapy. Supratentorial Neoplasms / secondary. Supratentorial Neoplasms / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 19336957.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin; 0 / Chorionic Gonadotropin, beta Subunit, Human; 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; UM20QQM95Y / Ifosfamide; BEP protocol; ICE protocol 1
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7. Schmid I, Stachel D, Graubner UB, Elsner R, Schulze S, Pöllinger B, Goetz C, Haas RJ: [Supratentorial primitive neuroectodermal tumor: a single center experience and comparison with the literature]. Klin Padiatr; 2005 May-Jun;217(3):153-7
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  • [Title] [Supratentorial primitive neuroectodermal tumor: a single center experience and comparison with the literature].
  • [Transliterated title] Supratentorieller primitiver neuroektodermaler Tumor: Erfahrungen in einem Zentrum im Vergleich zur Literatur.
  • All had craniospinal irradiation and chemotherapy according to the HIT-91 protocol.
  • The two children with incomplete resection died due to tumor progression after 7 and 10 months.
  • Two of the 4 children with complete tumor resection had local relapses 8 months after diagnosis and died after 14 and 18 months.
  • One child had a diffuse meningeal relapse 12 months after diagnosis.
  • Despite (high-dose) systemic chemotherapy and intraventricular mafosfamide, he died 21 months after diagnosis due to tumor although remission could be achieved.
  • Only one child is still in remission 86 months after diagnosis.
  • [MeSH-major] Brain Neoplasms. Cerebellar Nuclei. Corpus Callosum. Frontal Lobe. Neuroectodermal Tumors. Occipital Lobe. Parietal Lobe. Temporal Lobe. Thalamus
  • [MeSH-minor] Brain Stem Neoplasms / secondary. Cerebellar Neoplasms / mortality. Cerebellar Neoplasms / surgery. Child. Child, Preschool. Combined Modality Therapy. Disease Progression. Humans. Male. Mesencephalon. Neoplasm Recurrence, Local. Prognosis. Remission Induction. Time Factors

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  • (PMID = 15858707.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] ger
  • [Publication-type] Case Reports; Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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8. Yasuhara T, Tamiya T, Meguro T, Ichikawa T, Sato Y, Date I, Nakashima H, Ohmoto T: Glioblastoma with metastasis to the spleen--case report. Neurol Med Chir (Tokyo); 2003 Sep;43(9):452-6
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  • T1-weighted magnetic resonance (MR) imaging with contrast medium showed a mass lesion with ring-like enhancement in the right temporo-occipital lobe.
  • The patient underwent surgery, focal irradiation, and chemotherapy.
  • The histological diagnosis was glioblastoma.
  • Four months after the operation, the patient again developed headache and left homonymous hemianopsia in addition to vomiting and mild left hemiparesis.
  • MR imaging showed recurrence of the tumor and hydrocephalus.
  • Intraoperative findings revealed that the transverse-sigmoid sinus was occluded by tumor invasion.
  • Excessive therapy should not be used for patients with extracranial metastases from glioblastoma.
  • [MeSH-major] Brain Neoplasms / pathology. Glioblastoma / secondary. Splenic Neoplasms / secondary

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  • (PMID = 14560851.001).
  • [ISSN] 0470-8105
  • [Journal-full-title] Neurologia medico-chirurgica
  • [ISO-abbreviation] Neurol. Med. Chir. (Tokyo)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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9. Altinörs N, Calisaneller T, Gülşen S, Ozen O, Ongürü O: Intraventricular dysembryoplastic neuroepithelial tumor: case report. Neurosurgery; 2007 Dec;61(6):E1332-3; discussion E1333
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  • [Title] Intraventricular dysembryoplastic neuroepithelial tumor: case report.
  • OBJECTIVE: The most common localization of dysembryoplastic neuroepithelial tumors (DNTs) is the supratentorial cortex, often in the temporal lobe.
  • INTERVENTION: Neuroimaging results demonstrated a lesion located in the occipital horn of the right lateral ventricle.
  • The most recent neuroimaging examinations revealed neither residual nor recurrent tumor.
  • CONCLUSION: Because DNTs are surgically curable and neither radiotherapy nor chemotherapy is required after surgery, recognition of an intraventricular DNT in this location is extremely important.

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  • (PMID = 18162864.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Synaptophysin
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10. MacRae R, Grimard L, Hsu E, Nizalik E, Halton JM: Brain metastases in Wilms' tumor: case report and literature review. J Pediatr Hematol Oncol; 2002 Feb;24(2):149-53
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  • [Title] Brain metastases in Wilms' tumor: case report and literature review.
  • A 2-year-old girl who had a stage 2, favorable-histology Wilms tumor diagnosed when she was age 10 months presented with multiple brain metastases at second recurrence.
  • She had been treated with combined radiotherapy, surgery, and chemotherapy; at 2 months after treatment, recurrent disease developed in the central nervous system and she died.
  • Brain metastases are rare in the natural history of Wilms tumor.
  • Although it does not appear that cerebral metastases are a barrier to tumor eradication and long-term survival if treated with combined modality therapy, treatment should be individualized.
  • [MeSH-major] Brain Neoplasms / secondary. Frontal Lobe. Kidney Neoplasms. Occipital Lobe. Parietal Lobe. Wilms Tumor / secondary
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carboplatin / administration & dosage. Combined Modality Therapy. Craniotomy. Fatal Outcome. Female. Humans. Ifosfamide / administration & dosage. Infant. Lung Neoplasms / drug therapy. Lung Neoplasms / radiotherapy. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Mediastinal Neoplasms / drug therapy. Mediastinal Neoplasms / secondary. Mediastinal Neoplasms / surgery. Neoplasm Invasiveness. Neoplasm Recurrence, Local. Nephrectomy. Palliative Care. Paresis / etiology. Thoracotomy

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  • (PMID = 11990704.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; UM20QQM95Y / Ifosfamide
  • [Number-of-references] 25
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11. Akai T, Yamamoto K, Iida T, Iizuka H, Nojima T: Malignant fibrous histiocytoma in the craniocervical junction presenting with severe occipitalgia. Brain Tumor Pathol; 2006 Oct;23(2):101-5
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  • We report a patient who complained of severe occipitalgia caused by destruction of the atlantooccipital joint by tumor invasion.
  • Her symptoms were relieved by tumor resection and occipitocervical fixation.
  • Histological examination of the resected tumor revealed that the tumor cells had an irregular arrangement, remarkable atypia, and pleomorphism with multinucleated bizarre giant cells.
  • The tumor demonstrated no definitive sarcoma differentiation and was identified as malignant fibrous histiocytoma.
  • After tumor resection, the patient received adjuvant radiation and chemotherapy.
  • The tumor regrew outside the radiation field.
  • Chemotherapy with ifosfamide, cisplatin, and etoposide caused remarkable tumor reduction, but suspension of chemotherapy resulted in tumor recurrence.
  • The results of our drug protocol suggest that this regimen is feasible as postoperative adjuvant chemotherapy for malignant fibrous histiocytoma.
  • The role of adjuvant chemotherapy and radiation therapy for this highly malignant rare tumor should be evaluated in a prospective study with precise histological diagnosis.
  • [MeSH-major] Atlanto-Occipital Joint / pathology. Head and Neck Neoplasms / pathology. Headache / etiology. Histiocytoma, Malignant Fibrous / pathology
  • [MeSH-minor] Combined Modality Therapy. Fatal Outcome. Female. Fracture Fixation. Humans. Magnetic Resonance Imaging. Middle Aged. Neck Muscles / pathology. Neurosurgical Procedures. Occipital Lobe. Tomography, X-Ray Computed

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  • (PMID = 18095127.001).
  • [ISSN] 1433-7398
  • [Journal-full-title] Brain tumor pathology
  • [ISO-abbreviation] Brain Tumor Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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12. Engelhard HH: Tumor bed cyst formation after BCNU wafer implantation: report of two cases. Surg Neurol; 2000 Mar;53(3):220-4
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  • [Title] Tumor bed cyst formation after BCNU wafer implantation: report of two cases.
  • The purpose of this report is to alert neurosurgeons to an additional potential side effect: formation of a cystic mass within the implanted tumor bed.
  • CASE PRESENTATIONS: Two patients are described: a 54-year-old male, who presented with a large right parieto-occipital mass, and a 47-year-old woman with a large right frontal lobe tumor.
  • Both tumors were found on initial craniotomy to be glioblastoma multiforme; both recurred rapidly despite radiation therapy.
  • Patients were treated with a second craniotomy for tumor resection and placement of BCNU wafers.
  • After implantation, the first patient did well for 6 weeks, then developed lethargy, headaches, and vomiting.
  • In each case, minimal tumor and no evidence of infection were found.
  • CONCLUSIONS: The hypodense, roughly spherical cysts clearly demonstrated clinically significant mass effect, and required reoperation despite treatment with high-dose corticosteroids.
  • Neurosurgeons should be alert to the possibility of tumor bed cyst formation in patients treated with interstitial BCNU wafers.
  • [MeSH-major] Antineoplastic Agents, Alkylating / adverse effects. Brain Diseases / chemically induced. Brain Neoplasms / drug therapy. Carmustine / adverse effects. Cysts / chemically induced. Glioblastoma / drug therapy
  • [MeSH-minor] Chemotherapy, Adjuvant. Drug Implants. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / radiography

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  • (PMID = 10773252.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Drug Implants; U68WG3173Y / Carmustine
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13. Daneyemez M, Baysefer A, Can C, Timurkaynak E: Multiple oligodendroglioma: case report. Minim Invasive Neurosurg; 2000 Mar;43(1):51-2
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  • Magnetic resonance imaging (MRI) revealed a tumor in the left parieto-occipital lobe.
  • The tumor was totally removed, and postoperative radiation therapy was administered locally at 50 Gy.
  • Computed tomography (CT) and MRI demonstrated multiple mass lesions in the whole brain.
  • Following the systemic chemotherapy, removal of the largest tumor was performed.
  • [MeSH-major] Brain Neoplasms / surgery. Neoplasms, Second Primary / surgery. Oligodendroglioma / surgery
  • [MeSH-minor] Adolescent. Female. Headache / etiology. Humans. Magnetic Resonance Imaging. Occipital Lobe / pathology. Parietal Lobe / pathology. Unconsciousness / etiology

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  • (PMID = 10794567.001).
  • [ISSN] 0946-7211
  • [Journal-full-title] Minimally invasive neurosurgery : MIN
  • [ISO-abbreviation] Minim Invasive Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] GERMANY
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14. Buhl R, Hugo HH, Stark AM, Mihajlovic Z, Gottwald B, Mehdorn HM: Clinical experiences with oligoastrocytomas WHO grade II and III. Neurosurg Rev; 2004 Jul;27(3):218-23
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  • The tumor was localized in the frontal lobe in 22 patients, in the temporal lobe in seven patients, in the parietal lobe in nine patients and in the occipital lobe in one patient.
  • Postoperative radiotherapy was performed in 33 patients and chemotherapy in six patients.
  • One female patient developed spinal drop metastases 10 months after the operation.
  • [MeSH-major] Astrocytoma / therapy. Brain Neoplasms / therapy. Cerebral Cortex / surgery

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  • (PMID = 15045605.001).
  • [ISSN] 0344-5607
  • [Journal-full-title] Neurosurgical review
  • [ISO-abbreviation] Neurosurg Rev
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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15. Sell M, Mitrovics T, Sander BC: Primary nodular meningeal glioma mimicking metastatic tumor of the cerebellum with diffuse infra- and supratentorial leptomeningeal spread. Clin Neuropathol; 2000 May-Jun;19(3):126-30
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  • [Title] Primary nodular meningeal glioma mimicking metastatic tumor of the cerebellum with diffuse infra- and supratentorial leptomeningeal spread.
  • Magnetic resonance imaging showed an enhancing mass on the inferior aspect of the right cerebellar hemisphere as well as a thin, widespread leptomeningeal enhancement and T2-weighted hyperintense lesions in the left occipital lobe and both thalami.
  • Therefore, metastatic tumor of unknown origin was suggested.
  • Despite whole brain irradiation and intrathecal chemotherapy the patient deteriorated gradually and died four months later.
  • Post-mortem examination of the brain revealed a nodular, high-grade astrocytic tumor within the subarachnoid space on the lower portion of the right cerebellar hemisphere.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebellar Neoplasms / pathology. Glioma / secondary. Meningeal Neoplasms / secondary. Supratentorial Neoplasms / secondary
  • [MeSH-minor] Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 14606585.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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16. Nozaki M, Ohnishi A, Fujimaki T, Nagashima K, Cho K, Sawamura Y: Congenital gemistocytic astrocytoma in a fetus. Childs Nerv Syst; 2006 Feb;22(2):168-71
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  • INTRODUCTION: Congenital brain tumors, especially tumors diagnosed before birth, are very rare.
  • CASE REPORT: An intrauterine MRI revealed hydrocephalus and a mass lesion including massive hemorrhage in the right occipital lobe of a fetus.
  • The patient was delivered by cesarean section and a total excision of the hemorrhagic tumor was carried out on the third day of his life.
  • Neither adjuvant chemotherapy nor radiation was given after the first surgery.
  • Ten months after his birth, a recurrent tumor was depicted on follow-up MRI.
  • The second total excision of the recurrent tumor and chemotherapy using cisplatin and vincristine were performed.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Fetus
  • [MeSH-minor] Adult. Female. Glial Fibrillary Acidic Protein / metabolism. Humans. Immunohistochemistry / methods. Ki-67 Antigen / metabolism. Magnetic Resonance Imaging / methods. Pregnancy. Synaptophysin / metabolism. Tomography, X-Ray Computed / methods

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  • (PMID = 15864706.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein; 0 / Ki-67 Antigen; 0 / Synaptophysin
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17. Petridis AK, Hempelmann RG, Hugo HH, Eichmann T, Mehdorn HM: Metastatic low-grade inflammatory myofibroblastic tumor (IMT) in the central nervous system of a 29-year-old male patient. Clin Neuropathol; 2004 Jul-Aug;23(4):158-66
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  • [Title] Metastatic low-grade inflammatory myofibroblastic tumor (IMT) in the central nervous system of a 29-year-old male patient.
  • A case of myofibrosarcoma (IMT) of the brain and lung as well as the spinal cord is described.
  • Computer tomography identified a bleeding in the left frontal lobe.
  • The histological examination could not reveal an exact diagnosis.
  • Eight months after complete recovery from the first bleeding, the patient had a second intracranial temporo-occipital bleeding on the right side which has been removed operatively.
  • A new lesion was seen in the left parietal white matter of the brain.
  • The X-ray of the chest showed a pulmonary lesion in the left lower lobe.
  • In the CT of the chest a large tumor in the left lower lobe of the lung and additionally a cystic structure in the mediastinum was seen.
  • The histological examination of this tumor identified an inflammatory myofibroblastic tumor (IMT).
  • The brain lesions were estimated to be metastases of the IMT of the lung.
  • In the further clinical history the patient developed a large spinal cord metastasis of the thoracic spine.
  • The metastatic development of the tumor reported in this case is unusual.
  • The current therapy of these tumors consists of complete tumor resection and further clinical controls.
  • There is no proven role of chemotherapy and radiation therapy.
  • [MeSH-major] Central Nervous System Neoplasms / secondary. Fibrosarcoma / secondary. Lung Neoplasms / pathology. Neoplasms, Muscle Tissue / secondary
  • [MeSH-minor] Adult. Diagnosis, Differential. Hemangioma, Cavernous, Central Nervous System / pathology. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed

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  • (PMID = 15328880.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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18. Cohn DA, Stuart-Harris R: Isolated central nervous system relapse of non-seminomatous germ cell tumour of the testis. A case report and review of the literature. Oncology; 2001;61(3):184-8
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  • Long-term survival appears possible using multi-modal treatment with whole-brain radiotherapy, surgery and/or chemotherapy.
  • However, the optimal treatment of isolated CNS relapse remains undefined.
  • [MeSH-major] Brain Neoplasms / secondary. Carcinoma, Embryonal / secondary. Occipital Lobe. Testicular Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Cisplatin / administration & dosage. Combined Modality Therapy. Cranial Irradiation. Etoposide / administration & dosage. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Orchiectomy. Radiotherapy, Adjuvant. Remission Induction. Tomography, X-Ray Computed. Vision Disorders / etiology. alpha-Fetoproteins / analysis

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  • [Copyright] Copyright 2001 S. Karger AG, Basel
  • (PMID = 11574772.001).
  • [ISSN] 0030-2414
  • [Journal-full-title] Oncology
  • [ISO-abbreviation] Oncology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / alpha-Fetoproteins; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 10
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19. Shimato S, Wakabayashi T, Mizuno M, Nakahara N, Hatano H, Natsume A, Ishii D, Hasegawa Y, Hyodo I, Nagasaka T, Yoshida J: Brain metastases from apocrine carcinoma of the scalp: case report. J Neurooncol; 2006 May;77(3):285-9
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  • [Title] Brain metastases from apocrine carcinoma of the scalp: case report.
  • Apocrine carcinoma is an extremely rare malignant neoplasm that occurs most frequently in the axilla.
  • However, a literature search did not reveal any report describing the detailed clinical course of brain metastases from apocrine carcinoma.
  • We report a case of a 54-year-old male who suffered from multiple brain metastases from apocrine carcinoma that had originated in the scalp 6 years before.
  • The brain metastases appeared in spite of several regimens of chemotherapy for lung metastases for two years.
  • The tumor in the right frontal lobe was successfully operated.
  • However, the small tumor in the right occipital lobe was not cured by gamma knife surgery, and eventually required second operation.
  • To our knowledge this is the first reported case of metastatic brain tumor from apocrine carcinoma.
  • [MeSH-major] Apocrine Glands / pathology. Brain Neoplasms / secondary. Carcinoma / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Frontal Lobe / pathology. Frontal Lobe / surgery. Humans. Male. Middle Aged. Occipital Lobe / pathology. Occipital Lobe / surgery. Scalp / pathology

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  • (PMID = 16314948.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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20. Alexiou GA, Moschovi M, Stefanaki K, Prodromou C, Sfakianos G, Prodromou N: Malignant progression of a pleomorphic xanthoastrocytoma in a child. Neuropediatrics; 2010 Aug;41(2):69-71
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  • Pleomorphic xanthoastrocytoma (PXA) is a recently recognized rare cerebral neoplasm that predominantly affects young patients.
  • Radiological investigation revealed a lesion in the right parietal-occipital lobe.
  • 1 year later follow-up magnetic resonance imaging (MRI) revealed tumor relapse.
  • The patient received radiotherapy and 9 months later on follow-up MRI a new tumor recurrence was noted.
  • A third craniotomy was performed and the tumor removed.
  • The patient was referred to the oncology department and received chemotherapy with temozolamide.
  • 8 months later the patient was stable without tumor recurrence.
  • [MeSH-major] Astrocytoma / diagnosis. Brain Neoplasms / diagnosis. Brain Neoplasms / physiopathology. Glioblastoma / diagnosis
  • [MeSH-minor] Child, Preschool. Disease Progression. Gadolinium. Humans. Magnetic Resonance Imaging. Male. Tomography, X-Ray Computed / methods

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  • [Copyright] Georg Thieme Verlag KG Stuttgart.New York.
  • (PMID = 20799153.001).
  • [ISSN] 1439-1899
  • [Journal-full-title] Neuropediatrics
  • [ISO-abbreviation] Neuropediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] AU0V1LM3JT / Gadolinium
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21. Buhl R, Stark AM, Hugo HH, Rohr A, Mehdorn HM: Gliosarcoma: clinical experiences and additional information with MR spectroscopy. Neurol Res; 2009 Oct;31(8):873-7
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  • Six tumors were in the frontal lobe, four in the temporal lobe, three parietal, two in the thalamic area and one in the occipital lobe.
  • Median survival time in our patient group was 7 months (2-11 months).
  • On histological examination, we found glial fibrillary acid protein positive cells surrounded by sarcomatous tissue and reticular fibers.
  • MR spectroscopy and location of the tumor adjacent to the dura with inhomogeneous contrast enhancement might give hints pre-operatively for the differential diagnosis of gliosarcoma.
  • Further works with adjuvant chemotherapy are necessary.
  • [MeSH-major] Brain / pathology. Brain Neoplasms / pathology. Gliosarcoma / pathology
  • [MeSH-minor] Aged. Cell Proliferation. Diagnosis, Differential. Female. Glial Fibrillary Acidic Protein / metabolism. Humans. Magnetic Resonance Spectroscopy. Male. Middle Aged. Time Factors. Treatment Outcome

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  • (PMID = 19215667.001).
  • [ISSN] 0161-6412
  • [Journal-full-title] Neurological research
  • [ISO-abbreviation] Neurol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Glial Fibrillary Acidic Protein
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22. Mathews MS, Linskey ME, Hasso AN, Fruehauf JP: The effect of bevacizumab (Avastin) on neuroimaging of brain metastases. Surg Neurol; 2008 Dec;70(6):649-52; discussion 653
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  • [Title] The effect of bevacizumab (Avastin) on neuroimaging of brain metastases.
  • CASE DESCRIPTION: The authors report the case of a 54-year-old woman with metastatic infiltrating ductal breast carcinoma who developed left occipital and right parietal intraaxial contrast-enhancing masses on surveillance magnetic resonance imaging (MRI).
  • Six months later, a nonenhancing right occipital lesion was detected on MRI.
  • After stopping bevacizumab therapy, the patient underwent microsurgical resection of the lesion.
  • Histopathologic examination was consistent with metastatic breast cancer indistinguishable from her previously resected enhancing brain metastasis.
  • Six weeks after stopping bevacizumab therapy and 3 weeks after microsurgical resection, a new contrast-enhancing mass was noted on magnetic resonance in the right temporal lobe.
  • CONCLUSION: This case is unique in that we have neuroimaging on prebevacizumab, concurrent bevacizumab, and postbevacizumab brain metastases in the same patient with a single cancer primary, thus, assuring that alterations in neuroimaging characteristics are consistent with bevacizumab effect.
  • As an internal control, it provides strong support for the premise that bevacizumab therapy can confound the diagnosis of brain metastases because of its effect on tumor enhancement.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Antibodies, Monoclonal / therapeutic use. Brain Neoplasms / drug therapy. Brain Neoplasms / secondary. Carcinoma, Ductal, Breast / drug therapy. Carcinoma, Ductal, Breast / secondary
  • [MeSH-minor] Antibodies, Monoclonal, Humanized. Bevacizumab. Breast Neoplasms / drug therapy. Breast Neoplasms / pathology. Female. Humans. Magnetic Resonance Imaging. Middle Aged

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  • (PMID = 18261776.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 2S9ZZM9Q9V / Bevacizumab
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23. Varma AK, Muller PJ: Cranial neuropathies after intracranial Photofrin-photodynamic therapy for malignant supratentorial gliomas-a report on 3 cases. Surg Neurol; 2008 Aug;70(2):190-3
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  • [Title] Cranial neuropathies after intracranial Photofrin-photodynamic therapy for malignant supratentorial gliomas-a report on 3 cases.
  • BACKGROUND: In an RCT of PDT in the treatment of malignant gliomas, 3 patients developed cranial neuropathies after photoillumination.
  • All patients underwent surgical tumor extirpation.
  • There were 77 malignant gliomas, 2 meningiomas, and 1 metastatic tumor.
  • The tumor locations were as follows: 39 frontal, 25 temporal, 12 parietal, and 4 occipital.
  • Of the 25 patients with temporal lobe tumors, 18 received PDT.
  • RESULTS: Three of the 18 patients with temporal lobe tumors developed cranial neuropathies after PDT.
  • This complication was not seen in any other patient with tumors in the frontal, parietal, or occipital regions, or patients with temporal lobe tumors who did not receive PDT.
  • The first patient developed seventh nerve paresis and hypoesthesia in fifth nerve distribution, which resolved only partially.
  • The second patient developed a seventh nerve paresis that resolved completely.
  • The third patient developed transient neuralgic pain in the trigeminal nerve distribution.
  • [MeSH-major] Cranial Nerve Diseases / chemically induced. Dihematoporphyrin Ether / adverse effects. Glioma / drug therapy. Peripheral Nervous System Diseases / chemically induced. Photochemotherapy / adverse effects. Supratentorial Neoplasms / drug therapy
  • [MeSH-minor] Aged. Antineoplastic Agents / adverse effects. Cranial Fossa, Middle / pathology. Facial Nerve / anatomy & histology. Facial Nerve / drug effects. Facial Nerve / physiopathology. Facial Nerve Diseases / chemically induced. Facial Nerve Diseases / metabolism. Facial Nerve Diseases / physiopathology. Female. Humans. Light / adverse effects. Male. Middle Aged. Photic Stimulation / adverse effects. Preoperative Care / standards. Temporal Lobe / pathology. Temporal Lobe / physiopathology. Trigeminal Nerve / anatomy & histology. Trigeminal Nerve / drug effects. Trigeminal Nerve / physiopathology. Trigeminal Nerve Diseases / chemically induced. Trigeminal Nerve Diseases / metabolism. Trigeminal Nerve Diseases / physiopathology

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  • (PMID = 17976702.001).
  • [ISSN] 0090-3019
  • [Journal-full-title] Surgical neurology
  • [ISO-abbreviation] Surg Neurol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 97067-70-4 / Dihematoporphyrin Ether
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24. Papadia M, Herbort CP: Infliximab-induced demyelination causes visual disturbance mistaken for recurrence of HLA-B27-related uveitis. Ocul Immunol Inflamm; 2010 Dec;18(6):482-4
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  • PURPOSE: To report a patient treated with infliximab for ankylosing spondylitis and HLA-B27 uveitis presenting with a scotoma in his left good eye due to infliximab-induced occipital demyelination mistaken for a uveitis recurrence.
  • [MeSH-major] Antibodies, Monoclonal / adverse effects. Demyelinating Diseases / chemically induced. HLA-B27 Antigen / immunology. Occipital Lobe. Spondylitis, Ankylosing / drug therapy. Uveitis / drug therapy. Uveitis / immunology. Vision Disorders / chemically induced
  • [MeSH-minor] Adult. Angiography. Coloring Agents. Diagnostic Errors. Fluorescein Angiography. Humans. Indocyanine Green. Infliximab. Magnetic Resonance Imaging. Male. Recurrence. Scotoma / diagnosis. Scotoma / physiopathology. Tumor Necrosis Factor-alpha / antagonists & inhibitors. Visual Fields

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  • [CommentIn] Ocul Immunol Inflamm. 2010 Dec;18(6):421-3 [21091055.001]
  • (PMID = 20735341.001).
  • [ISSN] 1744-5078
  • [Journal-full-title] Ocular immunology and inflammation
  • [ISO-abbreviation] Ocul. Immunol. Inflamm.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Coloring Agents; 0 / HLA-B27 Antigen; 0 / Tumor Necrosis Factor-alpha; B72HH48FLU / Infliximab; IX6J1063HV / Indocyanine Green
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25. Tamburrini G, Colosimo C Jr, Giangaspero F, Riccardi R, Di Rocco C: Desmoplastic infantile ganglioglioma. Childs Nerv Syst; 2003 Jun;19(5-6):292-7
MedlinePlus Health Information. consumer health - Childhood Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Surgery is the treatment of choice.
  • Data available from the literature suggest that no complimentary treatment is needed in cases of complete tumor resection.
  • Chemotherapy is an option in infants with infiltration of eloquent CNS structures and progressive disease after surgery.
  • DIGs have generally a good prognosis: recurrence-free intervals of up to 14 years have been reported and spontaneous disappearance of tumor residuals has also been described.
  • The first child underwent a staged partial removal of a huge right fronto-temporo-parietal tumor when she was 2 months old.
  • At that time histological diagnosis was anaplastic astrocytoma and on these grounds she underwent six chemotherapy cycles, with a partial reduction of the tumor residual.
  • When she was 16 months old a new operation and complete removal of the tumor residual was performed; histological diagnosis was DIG.
  • A review of the initial histological samples confirmed this diagnosis.
  • Twenty-two months after surgery no tumor recurrence has been documented.
  • This case is an example of a difficult differential diagnosis, which can lead to incorrect management choices.
  • The second patient was operated on when he was 9 months old for a mostly cystic right temporo-parieto-occipital DIG.
  • MRI control 9 months after surgery showed the disappearance of the tumor residual.
  • Eleven years after surgery no tumor recurrence has been documented.
  • The history of this patient confirms that tumor residuals do not need complimentary treatment; indeed they do not usually grow and, as in our patient, they can spontaneously disappear.
  • [MeSH-major] Brain Neoplasms / pathology. Ganglioglioma / pathology
  • [MeSH-minor] Astrocytes / pathology. Child, Preschool. Female. Fibroblasts / pathology. Frontal Lobe / pathology. Frontal Lobe / surgery. Functional Laterality. Humans. Infant. Magnetic Resonance Imaging. Male. Neuroglia / pathology. Neurosurgical Procedures. Parietal Lobe / pathology. Parietal Lobe / surgery. Prognosis. Supratentorial Neoplasms / pathology. Supratentorial Neoplasms / surgery. Temporal Lobe / pathology. Temporal Lobe / surgery

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  • [CommentIn] Childs Nerv Syst. 2007 Jun;23(6):619-20; author reply 621 [17450367.001]
  • [Cites] Childs Nerv Syst. 2000 Jan;16(1):8-14 [10672423.001]
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  • (PMID = 12750935.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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26. Kakeya H, Inoue Y, Sawai T, Ikuta Y, Ohno H, Yanagihara K, Higashiyama Y, Miyazaki Y, Soda H, Tashiro T, Kohno S: [A case of brain metastasis discovered after surgery for lung cancer based on changes in CEA, in which long-term survival was obtained by repeated gammaknife irradiation]. Nihon Kokyuki Gakkai Zasshi; 2005 Dec;43(12):736-40
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of brain metastasis discovered after surgery for lung cancer based on changes in CEA, in which long-term survival was obtained by repeated gammaknife irradiation].
  • Since a high level of tumor marker CEA persisted after surgery, chemotherapy was additionally performed, and the CEA level subsequently normalized.
  • However, the CEA level increased in April 1999, and brain metastasis was found in the left occipital lobe, and the first gammaknife irradiation was performed.
  • Multiple brain metastases were found when CEA increased again in August 1999, and the second gammaknife irradiation was performed.
  • Moreover, brain metastases were found in the left frontal and occipital lobes in February 2000, and the third gammaknife irradiation was performed.
  • Brain metastasis was found in the right occipital lobe, and the fourth gammaknife irradiation was performed.
  • Long-term survival was possible by repeated gammaknife irradiation for brain metastases.
  • Monitoring of CEA played an important role in finding recurrent brain metastasis in this patient.
  • [MeSH-major] Adenocarcinoma / secondary. Adenocarcinoma / surgery. Brain Neoplasms / secondary. Brain Neoplasms / surgery. Radiosurgery

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  • (PMID = 16457335.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Carcinoembryonic Antigen
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27. Fujiuchi S: [Head and neck cancers. I. Retrograde, super-selective intra-arterial injection for oral cancer--an anatomical evaluation of the artery feeding the tumor and intra-arterial injection via occipital artery]. Gan To Kagaku Ryoho; 2009 Jul;36(7):1087-92
MedlinePlus Health Information. consumer health - Oral Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Head and neck cancers. I. Retrograde, super-selective intra-arterial injection for oral cancer--an anatomical evaluation of the artery feeding the tumor and intra-arterial injection via occipital artery].
  • [MeSH-major] Mouth Neoplasms / drug therapy
  • [MeSH-minor] Catheterization / methods. Cerebral Arteries / anatomy & histology. Humans. Injections, Intra-Arterial / methods. Occipital Lobe / blood supply

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  • (PMID = 19662710.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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