[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 23 of about 23
1. Oishi H, Matsumura Y, Ishida I, Sado T, Hoshikawa Y, Kondo T, Tachi M: [Sternal resection and chest wall reconstruction for primitive neuroectodermal tumor of the sternum]. Kyobu Geka; 2008 Sep;61(10):836-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sternal resection and chest wall reconstruction for primitive neuroectodermal tumor of the sternum].
  • Primitive neuroectodermal tumor of the sternum is rare.
  • A 59-year-old woman referred to our department with anterior chest pain and a tumor in the sternum.
  • The patient was diagnosed as primitive neuroectodermal tumor of the sternum by core biopsy of the lesion.
  • She received 2 cycles of preoperative chemotherapy with vincristine, doxorubicin, cyclophosphamide, ifosfamide, etoposide.
  • She underwent a total sternectomy with resection of adjacent bilateral costal cartilages and sternal ends of the clavicles.
  • [MeSH-major] Neuroectodermal Tumors, Primitive / surgery. Sternum / surgery. Thoracic Neoplasms / surgery. Thoracic Wall / surgery
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bacterial Proteins. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Humans. Membrane Transport Proteins. Middle Aged. Radiotherapy, Adjuvant. Reconstructive Surgical Procedures. Thoracic Surgical Procedures

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18788370.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Bacterial Proteins; 0 / FatB protein, Vibrio anguillarum; 0 / Membrane Transport Proteins
  •  go-up   go-down


2. Pavlakis G, Mountzios G, Terpos E, Leivaditou A, Papadopoulos G, Papasavas P: Recurrent ovarian cancer metastatic to the sternum, costae, and thoracic wall after prolonged treatment with platinum-based chemotherapy: a case report and review of the literature. Int J Gynecol Cancer; 2006 Jan-Feb;16 Suppl 1:299-303
Hazardous Substances Data Bank. VINBLASTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent ovarian cancer metastatic to the sternum, costae, and thoracic wall after prolonged treatment with platinum-based chemotherapy: a case report and review of the literature.
  • Sternal and costal metastases from ovarian cancer are extremely rare.
  • We present here a case of a 47-year-old woman with thoracic wall metastasis from serous-papillary ovarian carcinoma that occurred 3 years after the initial diagnosis, although the patient had received various regimens of intense platinum-based chemotherapy.
  • Special emphasis is given to the effects of alkylating agents, such as cisplatin and carboplatin, on the pattern of tumor spread.
  • We also discuss the possible mechanisms through which the biologic and metastatic behavior of this tumor is expressed.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Bone Neoplasms / drug therapy. Carboplatin / administration & dosage. Cisplatin / administration & dosage. Cystadenocarcinoma, Papillary / drug therapy. Ovarian Neoplasms / drug therapy
  • [MeSH-minor] Combined Modality Therapy. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Epirubicin / administration & dosage. Female. Gynecologic Surgical Procedures. Humans. Middle Aged. Neoplasm Recurrence, Local / therapy. Neoplasm Staging. Paclitaxel / administration & dosage. Ribs. Sternum. Taxoids / administration & dosage. Thoracic Wall. Topotecan / administration & dosage. Treatment Outcome. Vinblastine / administration & dosage. Vinblastine / analogs & derivatives

  • Genetic Alliance. consumer health - Ovarian cancer.
  • Genetic Alliance. consumer health - Metastatic cancer.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • Hazardous Substances Data Bank. DOCETAXEL .
  • Hazardous Substances Data Bank. Topotecan .
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • Hazardous Substances Data Bank. TAXOL .
  • Hazardous Substances Data Bank. CARBOPLATIN .
  • Hazardous Substances Data Bank. EPIRUBICIN .
  • Hazardous Substances Data Bank. VINORELBINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16515608.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Taxoids; 0W860991D6 / Deoxycytidine; 15H5577CQD / docetaxel; 3Z8479ZZ5X / Epirubicin; 5V9KLZ54CY / Vinblastine; 7M7YKX2N15 / Topotecan; B76N6SBZ8R / gemcitabine; BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin; Q6C979R91Y / vinorelbine
  • [Number-of-references] 10
  •  go-up   go-down


3. Sher-Ahmed A, Buscema J, Sardi A: A case report of recurrent epithelial ovarian cancer metastatic to the sternum, diaphragm, costae, and bowel managed by aggressive secondary cytoreductive surgery without postoperative chemotherapy. Gynecol Oncol; 2002 Jul;86(1):91-4
MedlinePlus Health Information. consumer health - Ovarian Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case report of recurrent epithelial ovarian cancer metastatic to the sternum, diaphragm, costae, and bowel managed by aggressive secondary cytoreductive surgery without postoperative chemotherapy.
  • BACKGROUND: Ovarian epithelial cancer typically presents in advanced stage and has been traditionally managed by a combination of cytoreductive surgery followed by adjuvant systematic chemotherapy.
  • The management of recurrent ovarian cancer has been individualized: surgical resection of intraabdominal and/or pelvic disease has been performed when technically feasible and usually followed with chemotherapy.
  • CASE: This case describes aggressive surgical management of recurrent ovarian cancer metastatic to the lower ribs, sternum, and diaphragm.
  • The patient had total abdominal hysterectomy, bilateral salpingo-oophorectomy, and omentectomy followed by six cycles of adjuvant chemotherapy, consisting of cyclophospamide and carboplatinum.
  • A secondary cytoreductive surgery without further chemotherapy has been the mainstay of treatment.
  • A combination of exploratory laparotomy and en bloc resection revealed the metastatic deposits, a 5-cm mass involving the diaphragm, the lower aspect of the manubrium sternum, and four right lower ribs.
  • [MeSH-major] Bone Neoplasms / secondary. Colonic Neoplasms / surgery. Neoplasm Recurrence, Local / surgery. Ovarian Neoplasms / surgery
  • [MeSH-minor] Aged. Diaphragm / pathology. Epithelial Cells / pathology. Female. Humans. Ribs. Sternum


Advertisement
4. Shiina Y, Oka T, Komoda K: [Mediastinal non seminomatous germ cell tumor successfully treated with chemotherapy and curative surgery; report of a case]. Kyobu Geka; 2004 Mar;57(3):241-4
Hazardous Substances Data Bank. ETOPOSIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Mediastinal non seminomatous germ cell tumor successfully treated with chemotherapy and curative surgery; report of a case].
  • A 20-year-old male was clinically diagnosed as having a mediastinal non seminomatous germ cell tumor because of the elevation of the serum AFP and a large mass lesion in the anterior mediastinal and right thoracic cavity.
  • After 3 courses of chemotherapy with cisplatin (CDDP) and etoposide (VP-16), the serum level decreased to normal range.
  • But, the mediastinal mass enlarged after chemotherapy due to hemorrhage.
  • The tumor was completely removed with sternotomy and right thoracotomy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Mediastinal Neoplasms / surgery. Neoplasms, Germ Cell and Embryonal / surgery. Pneumonectomy / methods
  • [MeSH-minor] Adult. Bleomycin / administration & dosage. Cisplatin / administration & dosage. Etoposide / administration & dosage. Humans. Male. Neoplasm Invasiveness. Salvage Therapy. Sternum / surgery. Thoracotomy / methods. Treatment Outcome

  • Hazardous Substances Data Bank. BLEOMYCIN .
  • Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15035084.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


5. Nikpoor N, Aliabadi P, Diaz L, Mannting F: Long-term follow-up of residual mediastinal-hilar Ga-67 uptake after treatment for Hodgkin's and non-Hodgkin's lymphomas: what degree of Ga-67 uptake is significant? Clin Nucl Med; 2000 Dec;25(12):959-62
MedlinePlus Health Information. consumer health - Hodgkin Disease.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term follow-up of residual mediastinal-hilar Ga-67 uptake after treatment for Hodgkin's and non-Hodgkin's lymphomas: what degree of Ga-67 uptake is significant?
  • PURPOSE: Ga-67 planar and SPECT images of 85 patients after treatment for mediastinal-hilar (M-H) lymphoma were reviewed retrospectively.
  • The entire period was 7 years after diagnosis.
  • The main goal was visual assessment of the significance of mild (grades 1 or 2) Ga-67 uptake in the M-H area as compared with Ga-67 uptake in bone marrow.
  • METHODS: Residual Ga-67 mediastinal uptake after a complete course of chemotherapy or other treatments was defined as normal (no residual) M-H uptake, borderline (M-H residual uptake with intensity less than that or equal to the sternum, spine, or both), and abnormal (M-H residual uptake with intensity greater than that of the sternum or spine).
  • The two patients (2%) with abnormal (M-H) uptake never responded to treatment.
  • No significant statistical difference in tumor recurrence was found between no residual and borderline uptake (P = 0.21).
  • CONCLUSIONS: Visual assessment of M-H Ga-67 uptake (without quantification) could be useful to differentiate active residual tumor from nonactive residual uptake.
  • [MeSH-major] Gallium Radioisotopes. Hodgkin Disease / radionuclide imaging. Lymphoma, Non-Hodgkin / radionuclide imaging. Mediastinal Neoplasms / radionuclide imaging. Tomography, Emission-Computed, Single-Photon
  • [MeSH-minor] Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / radionuclide imaging. Prognosis. Retrospective Studies. Time Factors

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11129161.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gallium Radioisotopes
  •  go-up   go-down


6. Yuasa H, Katsumine Y, Uehara S, Noda N, Osawa I: [Three cases of advanced breast cancer successfully treated with a weekly dose of paclitaxel]. Gan To Kagaku Ryoho; 2005 Apr;32(4):533-7
Hazardous Substances Data Bank. TAXOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Case 1: A 52-year-old female, diagnosed as having bilateral breast cancer with metastatis to right lung (S9) and sternum.
  • A TXL weekly regimen was started (80 mg/m2 with the administration of the drug for three weeks followed by one week rest as one course).
  • After twelve courses of treatment, bilateral breast masses significantly regressed with the disappearance of bilateral axillary and parasternal lymph node metastasis.
  • The tumor marker was normalized, too.
  • As a result of two courses of weekly TXL therapy, the tumor responded significantly and a modified mastectomy was conducted.
  • The TXL weekly regimen seems to be very effective in regressing breast tumors and can be given safely in the outpatient setting with an extremely high utility profile as neoadjuvant chemotherapy as well.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Breast Neoplasms / drug therapy. Carcinoma, Ductal, Breast / drug therapy. Nitriles / administration & dosage. Paclitaxel / administration & dosage. Triazoles / administration & dosage
  • [MeSH-minor] Antineoplastic Agents, Hormonal / administration & dosage. Bone Neoplasms / secondary. Drug Administration Schedule. Female. Humans. Lung Neoplasms / secondary. Mastectomy, Modified Radical. Middle Aged. Neoplasm Invasiveness. Skin Neoplasms / pathology. Sternum

  • Genetic Alliance. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • Hazardous Substances Data Bank. ANASTROZOLE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15853223.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Nitriles; 0 / Triazoles; 2Z07MYW1AZ / anastrozole; P88XT4IS4D / Paclitaxel
  •  go-up   go-down


7. Oshikawa G, Arai A, Sasaki K, Ichinohasama R, Miura O: [Primary multifocal osseous Hodgkin lymphoma]. Rinsho Ketsueki; 2009 Feb;50(2):92-6
Hazardous Substances Data Bank. VINBLASTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Despite normal findings on X-ray and CT scan at a previous hospital, sternal tumor had arisen and fever, night sweat, and weight loss developed 5 months before admission.
  • Core needle biopsy of the sternal tumor was performed and a diagnosis of Hodgkin lymphoma (HL) (mixed cellularity) was made.
  • FDG-PET scan demonstrated increased FDG uptake in the sternum, the right ilium, the right 9(th) rib, and the lower edge of the left scapula, but there were no other apparent lesions.
  • Neither bone marrow biopsy nor cerebrospinal fluid examination showed infiltration of lymphoma cells.
  • Primary osseous HL confined to the bone is so rare that only 16 cases have been reported worldwide to date, with none of these cases being from Japan.
  • Since there have not yet been any characteristic symptoms or laboratory findings identified, the diagnosis of osseous HL is difficult and may be delayed.
  • Although systemic chemotherapy appears to have been effective in the reported cases, more cases should be reviewed to clarify its pathophysiological features.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hodgkin Disease / diagnosis. Neoplasms, Multiple Primary
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / administration & dosage. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Humans. Positron-Emission Tomography. Remission Induction. Tomography, X-Ray Computed. Vinblastine / administration & dosage

  • Genetic Alliance. consumer health - Hodgkin lymphoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • MedlinePlus Health Information. consumer health - Hodgkin Disease.
  • Hazardous Substances Data Bank. BLEOMYCIN .
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. DACARBAZINE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19265301.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5V9KLZ54CY / Vinblastine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; ABVD protocol
  • [Number-of-references] 15
  •  go-up   go-down


8. Shiono S, Abiko M, Tamura G, Sato T: Malignant solitary fibrous tumor with superior vena cava syndrome. Gen Thorac Cardiovasc Surg; 2009 Jun;57(6):321-3
Genetic Alliance. consumer health - Superior vena cava syndrome.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant solitary fibrous tumor with superior vena cava syndrome.
  • We report a case of malignant solitary fibrous tumor with superior vena cava syndrome and highly aggressive behavior.
  • Postoperative radiotherapy was performed due to incomplete resection, but the tumor relapsed within 4 months.
  • Gemcitabine-based chemotherapy was ineffective.
  • [MeSH-minor] Adult. Deoxycytidine / analogs & derivatives. Deoxycytidine / therapeutic use. Fatal Outcome. Female. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Neoplasm Invasiveness. Pleural Neoplasms / drug therapy. Pleural Neoplasms / secondary. Radiotherapy, Adjuvant. Sternum / surgery. Tomography, X-Ray Computed. Treatment Outcome. Vascular Surgical Procedures

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Chest. 2007 Mar;131(3):904-908 [17356113.001]
  • [Cites] Am J Surg Pathol. 1989 Aug;13(8):640-58 [2665534.001]
  • [Cites] Am J Surg Pathol. 1989 Jul;13(7):547-57 [2735490.001]
  • [Cites] Ann Thorac Surg. 2002 Jul;74(1):285-93 [12118790.001]
  • [Cites] Eur J Cardiothorac Surg. 1998 Nov;14(5):453-9 [9860200.001]
  • [Cites] Thorac Cardiovasc Surg. 2004 Apr;52(2):110-2 [15103584.001]
  • [Cites] Postgrad Med J. 1989 Oct;65(768 ):788-90 [2616410.001]
  • (PMID = 19533281.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
  •  go-up   go-down


9. Milardovic R, Castellon I, Mills C, Altinyay ME, Raphael B, Abdel-Dayem HM: Scintigraphic visualization of an epigastric sentinel node in recurrent breast cancer after lumpectomy and postoperative radiation therapy. Clin Nucl Med; 2006 Apr;31(4):207-8
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scintigraphic visualization of an epigastric sentinel node in recurrent breast cancer after lumpectomy and postoperative radiation therapy.
  • Failure to visualize a sentinel lymph node in recurrent breast cancer after treatment by surgery, chemotherapy, and high-dose postoperative radiation therapy is almost the case in every patient.
  • The reason for failure to visualize the sentinel node is the fibrosis that follows high-dose radiotherapy and blocks the lymphatics preventing spread of the tumor cells to the lymph nodes.
  • Alternative pathways for the drainage of lymph from the breast are developed in these patients.
  • In this report, we are presenting another alternative pathway of lymphatics to the region of the epigastrium below the lower end of the sternum.
  • [MeSH-minor] Female. Humans. Lymph Node Excision. Mastectomy, Segmental. Middle Aged. Neoplasm Recurrence, Local. Sentinel Lymph Node Biopsy. Sternum

  • Genetic Alliance. consumer health - Breast Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16550014.001).
  • [ISSN] 0363-9762
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


10. Chapelier A, Fadel E, Macchiarini P, Lenot B, Le Roy Ladurie F, Cerrina J, Dartevelle P: Factors affecting long-term survival after en-bloc resection of lung cancer invading the chest wall. Eur J Cardiothorac Surg; 2000 Nov;18(5):513-8
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Several reports emphasize the importance of en-bloc resection as the optimal surgical treatment of lung cancer with chest wall invasion.
  • Chest wall resection also extended to the sternum in one patient, the transverse process in one, the costotransverse foramen and hemivertebrae in two.
  • Sixty-three patients received postoperative radiotherapy and 12 received chemotherapy.
  • The role of induction chemotherapy for tumors with poor prognosis should be investigated.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Analysis of Variance. Combined Modality Therapy. Female. Follow-Up Studies. Hospital Mortality. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Prognosis. Proportional Hazards Models. Risk Factors. Survival Analysis. Treatment Outcome

  • Genetic Alliance. consumer health - Lung Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11053809.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  •  go-up   go-down


11. Krüger M, Uschinsky K, Engelmann C: [Surgical treatment of malignant thoracic schwannomas]. Zentralbl Chir; 2001 Mar;126(3):223-8
MedlinePlus Health Information. consumer health - Lung Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Surgical treatment of malignant thoracic schwannomas].
  • [Transliterated title] Chirurgische Therapie thorakaler maligner Schwannome.
  • The objective of this study is to evaluate the results after surgical treatment of malignant tumors arising from the peripheral nerves of the thorax under consideration of adjuvant therapy modalities.
  • PATIENTS AND METHODS: Between 1988 and 1998, 9 patients (6 males, 3 females) underwent surgical treatment for MTNSO and 35 pts. for benign neurogenic tumors.
  • RESULTS: In patients with MTNSO partial chest wall resections (n = 4) including sternectomy (n = 1), lung resections (n = 2), paravertebral (n = 1) and mediastinal tumor resection (n = 1) and palliative resection of pleural recurrence (n = 1) were performed.
  • Adjuvant therapy was performed in two pts. (adjuvant radiotherapy/chemotherapy for metastatic disease n = 1; adjuvant chemotherapy/adjuvant radiotherapy after resection of recurrent tumor n = 1).
  • Three pts. died 8, 9 and 26 months after the primary surgical procedure.
  • CONCLUSION: Patients with MTNSO have an unfavourable prognosis and local recurrence is frequent even after radical surgical therapy.
  • Therefore an adjuvant treatment in these patients may be justified, even if the value of these therapy modalities is not proved yet.
  • A tumor-free long-term survival especially after complete surgical resection is possible in selected cases.
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Combined Modality Therapy. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Palliative Care. Prognosis. Radiotherapy, Adjuvant. Sternum / surgery. Time Factors. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11301889.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


12. Kodate M, Takagishi T, Osaki T: [Plasmacytoma of chest wall]. Kyobu Geka; 2010 Sep;63(10):879-82

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a 70-year-old man who suffered from right anterior chest wall tumor.
  • Chest X-ray and computed tomography (CT) revealed enhanced mass and destruction of the 4th rib.
  • As needle aspiration cytology did not define the diagnosis, we performed a chest wall resection and reconstruction.
  • Histological diagnosis of the tumor was plasmacytoma (IgG lambda type).
  • Five months after the operation, the tumor recurred at the right anterior chest wall.
  • Radiotherapy was performed with dose of 50 Gy.
  • Fourteen months after the operation, the tumor recurred at the lower sternum, and the chemotherapy was performed using ranimustine, vincristine, melpharan and dexamethasone.
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Recurrence, Local. Thoracoplasty

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20845698.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


13. Sawai K, Nakajima H, Mizuta N, Sakaguchi K, Hachimine Y: [Key issues in sentinel node biopsy for breast cancer]. Gan To Kagaku Ryoho; 2004 Aug;31(8):1271-4
MedlinePlus Health Information. consumer health - Breast Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SNB for patients with ductal carcinoma in situ (DCIS) may be performed according to the decision of doctors or patients in each case, because the indication of SNB for DCIS is controversial.
  • Since preoperative chemotherapy could increase the rate of false-negative sentinel nodes because of the induced lymphatic changes, SNB is thought to be safer before than after preoperative chemotherapy.
  • Current evidence does not allow internal mammary SNB to be recommended as a standard procedure, but as patients with internal mammary node involvement may benefit from adjuvant systemic treatment, internal mammary SNB should be further studied in this context.
  • Preoperative diagnosis of an axillary metastasis using fine-needle aspiration cytology (FNAC) under ultrasonographical imaging or core needle biopsy under MR imaging can cost-effectively decrease the indications of SNB.
  • [MeSH-major] Breast Neoplasms / pathology. Lymph Nodes / pathology. Neoplasm Staging / classification. Sentinel Lymph Node Biopsy
  • [MeSH-minor] Carcinoma, Intraductal, Noninfiltrating / pathology. Female. Humans. Lymph Node Excision. Lymphatic Metastasis / pathology. Sternum

  • Genetic Alliance. consumer health - Breast Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15332557.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 18
  •  go-up   go-down


14. Edwards JG, Martin-Ucar AE, Stewart DJ, Waller DA: Right extrapleural pneumonectomy for malignant mesothelioma via median sternotomy or thoracotomy? Short- and long-term results. Eur J Cardiothorac Surg; 2007 May;31(5):759-64
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Operation time was faster with median sternotomy than right thoracotomy (p=0.008).
  • Planned neoadjuvant or adjuvant chemotherapy was more common following median sternotomy than right thoracotomy (p=0.01).
  • [MeSH-minor] Analgesia, Epidural / methods. Antineoplastic Agents / therapeutic use. Case-Control Studies. Cisplatin / therapeutic use. Humans. Kaplan-Meier Estimate. Neoadjuvant Therapy / methods. Neoplasm Staging. Postoperative Period. Retrospective Studies. Sternum / surgery. Thoracotomy / methods. Time Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17350854.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin
  •  go-up   go-down


15. Kim SS, Radford J, Harris M, Varley J, Rutherford AJ, Lieberman B, Shalet S, Gosden R: Ovarian tissue harvested from lymphoma patients to preserve fertility may be safe for autotransplantation. Hum Reprod; 2001 Oct;16(10):2056-60
ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Ovarian tissue harvested from lymphoma patients to preserve fertility may be safe for autotransplantation.
  • The safety issue, however, is of great concern because residual disease in autografted ovarian tissues might cause recrudescence of disease.
  • METHODS: A total of 30 non-obese diabetic severe combined immunodeficient (NOD/LtSz-SCID) mice were individually xenografted s.c. with frozen-thawed ovarian tissue from 18 patients with lymphoma [13 Hodgkin's lymphoma (HL) and 5 non-Hodgkin's lymphoma (NHL)].
  • The xenograft, liver, spleen, sternum, para-aortic lymph nodes and thymus were prepared for histology, immunohistochemistry and human DNA microsatellite analysis.
  • RESULTS: None of the animals grafted with ovarian tissue from lymphoma patients developed disease.
  • However, all 3 animals grafted with lymph node tissue from an NHL patient developed B-cell lymphomas that were confirmed as human in origin by DNA microsatellite analysis.
  • CONCLUSION: Ovarian tissue harvested before high-dose chemotherapy for HL or NHL may not carry a risk of disease transmission by autotransplantation, although the possibility is difficult to exclude completely.
  • [MeSH-major] Fertility. Infertility, Female / prevention & control. Lymphoma / physiopathology. Lymphoma / surgery. Ovary / transplantation. Tissue and Organ Harvesting
  • [MeSH-minor] Adult. Animals. Female. Hodgkin Disease / physiopathology. Hodgkin Disease / surgery. Humans. Lymphoma, B-Cell / genetics. Lymphoma, B-Cell / pathology. Lymphoma, Non-Hodgkin / genetics. Lymphoma, Non-Hodgkin / physiopathology. Lymphoma, Non-Hodgkin / surgery. Mice. Mice, SCID. Microsatellite Repeats. Neoplasm Invasiveness. Thymus Gland / pathology. Transplantation, Autologous. Transplantation, Heterologous

  • MedlinePlus Health Information. consumer health - Female Infertility.
  • MedlinePlus Health Information. consumer health - Lymphoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11574491.001).
  • [ISSN] 0268-1161
  • [Journal-full-title] Human reproduction (Oxford, England)
  • [ISO-abbreviation] Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


16. Kadota Y, Utsumi T, Inoue M, Sawabata N, Minami M, Okumura M: Radiation-induced osteosarcoma 17 years after mediastinal irradiation following surgical removal of thymoma. Gen Thorac Cardiovasc Surg; 2010 Dec;58(12):651-3
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a rare case of radiation-induced osteosarcoma of the sternum after mediastinal irradiation of a thymoma.
  • A 49-year-old woman presented with a sternal tumor 17 years after surgery plus mediastinal irradiation (50 Gy) for a stage III thymoma.
  • On biopsy, this second tumor was diagnosed as a radiation-induced osteosarcoma.
  • Despite intensive combination chemotherapy that initially stabilized her disease, the patient died 2 years after the diagnosis was made.
  • [MeSH-major] Bone Neoplasms / etiology. Neoplasms, Radiation-Induced / etiology. Osteosarcoma / etiology. Sternum / radiation effects. Thymectomy. Thymoma / therapy. Thymus Neoplasms / therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Fatal Outcome. Female. Humans. Middle Aged. Radiotherapy, Adjuvant / adverse effects. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

  • Genetic Alliance. consumer health - Osteosarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • MedlinePlus Health Information. consumer health - Thymus Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Clin Orthop Relat Res. 2006 Sep;450:76-81 [16906097.001]
  • [Cites] J Clin Oncol. 1999 Apr;17(4):1164 [10561175.001]
  • [Cites] Ann Surg Oncol. 1996 Jul;3(4):387-92 [8790852.001]
  • [Cites] J Thorac Cardiovasc Surg. 2008 Dec;136(6):1481-5 [19114194.001]
  • [Cites] Cancer. 1998 Jan 1;82(1):8-34 [9428476.001]
  • [Cites] J Clin Oncol. 2003 May 15;21(10):2011-8 [12743156.001]
  • [Cites] J Chemother. 2001 Jun;13(3):324-30 [11450892.001]
  • [Cites] Breast J. 2002 Sep-Oct;8(5):320-2 [12199765.001]
  • [Cites] Cancer. 2002 Feb 1;94(3):624-32 [11857293.001]
  • (PMID = 21170638.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


17. Suehara Y, Yazawa Y, Hitachi K, Terakado A: Clear cell sarcoma arising from the chest wall: a case report. J Orthop Sci; 2004;9(2):171-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Clear cell sarcoma is a rare malignant soft tissue neoplasm that usually arises adjacent to tendons or aponeuroses.
  • The principal sites of this neoplasm are the extremities, but tumors do occur in the trunk on rare occasions.
  • On immunohistochemical examination, tumor cells were strongly immunoreactive for S-100 and HMB-45.
  • A diagnosis of clear cell sarcoma was confirmed.
  • She was treated with two courses of chemotherapy using ifosfamide, carboplatin, and etoposide.
  • Subsequently, the tumor, including adjacent tissue, the chest wall, and sternum, was resected with a wide margin; and the defect of the chest wall was covered with Marlex mesh fabric, regin, and a musculocutaneous flap.
  • [MeSH-major] Sarcoma, Clear Cell / diagnosis. Soft Tissue Neoplasms / diagnosis. Thoracic Neoplasms / diagnosis. Thoracic Wall

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15045547.001).
  • [ISSN] 0949-2658
  • [Journal-full-title] Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
  • [ISO-abbreviation] J Orthop Sci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


18. Falco CE, Grande AM, Nicolardi S, Viganò M, Benazzo M: Management of anaplastic thyroid carcinoma spread over the trachea with mediastinal extension. G Chir; 2010 Aug-Sep;31(8-9):390-3
MedlinePlus Health Information. consumer health - Thyroid Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • INTRODUCTION: We report a case of treatment of anaplastic thyroid carcinoma spread over the trachea with mediastinal extension.
  • METHODS: Case report and review of the world literature concerning the treatment of anaplastic thyroid carcinoma are presented.
  • DISCUSSION: The role of surgery in treatment of anaplastic carcinoma remains controversial.
  • Even if curative resection cannot be achieved, surgical resection can immediately reduce the tumor bulk to facilitate the efficacy of post-operative radiotherapy and/or chemotherapy and to achieve a good local control to avoid the need of a subsequent palliative tracheostomy.
  • Tumor upper mediastinal involvement made mandatory to open the sternum in order to allow a more complete resection of the macroscopic mass.
  • CONCLUSION: The complete resection of the tumor mass without scarifying vital structures can lead to some prolonged survival.
  • [MeSH-minor] Fatal Outcome. Female. Humans. Laryngectomy. Middle Aged. Neoplasm Staging. Thyroidectomy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20843444.001).
  • [ISSN] 0391-9005
  • [Journal-full-title] Il Giornale di chirurgia
  • [ISO-abbreviation] G Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


19. Kunisue H, Kurebayashi J, Sonoo H, Udagawa K, Yamamoto Y, Yamamoto S, Tanaka K, Shimozuma K: [A case of advanced breast cancer associated with humoral hypercalcemia that responded to medroxyprogesterone acetate and docetaxel]. Gan To Kagaku Ryoho; 2000 Jul;27(7):1043-6
Hazardous Substances Data Bank. TAXOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chest CT revealed a parasternal lymph nodal metastasis invading into the sternum, an axillary lymph nodal metastasis, and a lung metastasis.
  • After controlling the hypercalcemia with alendronate, sodium hydrate she received chemoendocrine therapy with medroxyprogesterone acetate (MPA) (800 mg/day) and docetaxel (60 mg/body once every three weeks).
  • This case suggests the efficacy of the combined therapy with MPA and docetaxel on advanced breast cancers.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Breast Neoplasms / drug therapy. Hypercalcemia / complications. Lymph Nodes / pathology. Taxoids
  • [MeSH-minor] Administration, Oral. Aged. Axilla. Drug Administration Schedule. Female. Humans. Lymphatic Metastasis. Medroxyprogesterone Acetate / administration & dosage. Neoplasm Invasiveness. Paclitaxel / administration & dosage. Paclitaxel / analogs & derivatives

  • Genetic Alliance. consumer health - Breast Cancer.
  • MedlinePlus Health Information. consumer health - Breast Cancer.
  • Hazardous Substances Data Bank. DOCETAXEL .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 10925692.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel; C2QI4IOI2G / Medroxyprogesterone Acetate; P88XT4IS4D / Paclitaxel
  •  go-up   go-down


20. Yang YM, Liu T: [Complete remission of acute promyelocytic leukemia resisting all-trans retinoic acid of one case treated by tanshinone II A]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2006 Nov;37(6):965-7
Hazardous Substances Data Bank. ALL-TRANS-RETINOIC ACID .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The physical examination (PE) discovered that the case suffered from the anemic appearance, lower part tenderness of sternum, petechiae and purpura on skin of lower extremities, and with remaining not to be remarkable.
  • 85. The bone marrow smear indicated markedly the hypercellularity, promyelocytes 89% and strongly positive myeloperoxidase (MPO).
  • The patient was administered with all-trans retinoic acid (ATRA) with dosage of 20 mg three times per day.
  • After 14 week treatment, the patient did not get complete remission.
  • After 8 week treatment of tanshinone II A, the blood routine was restored to normal.
  • Four weeks later, the bone marrow also became normally, and the patient got a complete remission (CR).
  • After more than 3 months of consolidation therapy with tanshinone II A, the patient was relapsed.
  • The tanshinone II A could induce CR of APL with ATRA resistance, no side effect was observed; there is a reoccurring possibility from consolidation therapy with tanshinone II A.
  • [MeSH-major] Drug Resistance, Neoplasm. Leukemia, Promyelocytic, Acute / drug therapy. Phenanthrenes / therapeutic use. Remission Induction / methods. Tretinoin / pharmacology

  • Genetic Alliance. consumer health - Acute Promyelocytic Leukemia.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17236602.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Diterpenes, Abietane; 0 / Phenanthrenes; 03UUH3J385 / tanshinone; 5688UTC01R / Tretinoin
  •  go-up   go-down


21. Wegener B, Müller PE, Jansson V, Krödel A, Heinert G, Dürr HR: Cervical spine metastasis of multiple myeloma: a case report with 16 years of follow-up. Spine (Phila Pa 1976); 2004 Sep 1;29(17):E368-72
MedlinePlus Health Information. consumer health - Neck Injuries and Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It slowly causes bone destruction due to bone marrow infiltration.
  • RESULTS: Initial surgical treatment was aimed at palliation.
  • The patient died 16 years after the first procedure due to progression of the disease.
  • Surgical interventions must take into account the relatively long period of survival in multiple myeloma patients compared to patients with other secondary bone tumors.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Combined Modality Therapy. Disease Progression. Fatal Outcome. Follow-Up Studies. Humans. Ilium / radiography. Magnetic Resonance Imaging. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Osteolysis / etiology. Osteolysis / radiography. Palliative Care. Radiotherapy, Adjuvant. Reoperation. Sacrum / radiography. Spinal Stenosis / etiology. Spinal Stenosis / surgery. Sternum / radiography. Thoracic Vertebrae / radiography. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Multiple myeloma.
  • MedlinePlus Health Information. consumer health - Multiple Myeloma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15534399.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


22. Mihălţan F, Munteanu I, Trenchea M, Bădescu C, Arghir OC, Ulmeanu D, Galbenu P: [Sternal chondrosarcoma and the complications poststernectomy]. Pneumologia; 2009 Oct-Dec;58(4):233-8
Hazardous Substances Data Bank. OXYGEN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Sternal chondrosarcoma and the complications poststernectomy].
  • [Transliterated title] Condrosarcomul sternal şi complicaţiile poststernectomie.
  • Primary tumors of the sternum are unusual, and, of these chondrosarcoma is extremely rare.
  • It is difficult to deduce from the roengenographic and pathologic findings the presence of a sternal tumor.
  • This case report of primary sternal chondrosarcoma illustrated an extremely rare cartilaginous lesion in a male 64 years old.
  • Extensive sternal excision was indicated despite the apparent benignity of the tumor.
  • This aggressive surgical method facilitated the diagnosis of a malignant tumor with moderate cellular differentiation G2 chondrosarcoma.
  • [MeSH-major] Bone Neoplasms / surgery. Chondrosarcoma / surgery. Pleural Effusion / radiography. Pleural Effusion / therapy. Sternum / surgery
  • [MeSH-minor] Anti-Bacterial Agents / therapeutic use. Drainage. Drug Therapy, Combination. Glucocorticoids / therapeutic use. Humans. Male. Middle Aged. Oxygen / therapeutic use. Risk Factors. Treatment Outcome

  • Genetic Alliance. consumer health - Chondrosarcoma.
  • MedlinePlus Health Information. consumer health - Bone Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20067058.001).
  • [ISSN] 2067-2993
  • [Journal-full-title] Pneumologia (Bucharest, Romania)
  • [ISO-abbreviation] Pneumologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Glucocorticoids; S88TT14065 / Oxygen
  •  go-up   go-down


23. Bobek V, Plachy J, Pinterova D, Kolostova K, Boubelik M, Jiang P, Yang M, Hoffman RM: Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model. Clin Exp Metastasis; 2004;21(4):347-52

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Development of a green fluorescent protein metastatic-cancer chick-embryo drug-screen model.
  • The chick-embryo model has been an important tool to study tumor growth, metastasis, and angiogenesis.
  • However, an imageable model with a genetic fluorescent tag in the growing and spreading cancer cells that is stable over time has not been developed.
  • GFP-Lewis lung carcinoma metastases were visualized by fluorescence, after seven days additional incubation, in the brain, heart, and sternum of the developing chick embryo, with the most frequent site being the brain.
  • [MeSH-major] Deoxycytidine / analogs & derivatives. Disease Models, Animal. Drug Screening Assays, Antitumor / methods. Green Fluorescent Proteins / metabolism. Neoplasm Metastasis / prevention & control
  • [MeSH-minor] Animals. Carcinoma, Lewis Lung / drug therapy. Chick Embryo. Mice. Mice, Inbred C57BL. Streptokinase / administration & dosage

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Eur J Cancer. 1999 May;35(5):808-14 [10505043.001]
  • [Cites] Proc Soc Exp Biol Med. 1954 Oct;87(1):223-7 [13224733.001]
  • [Cites] Blood Coagul Fibrinolysis. 1995 Apr;6(2):105-12 [7605874.001]
  • [Cites] Lancet Oncol. 2002 Sep;3(9):546-56 [12217792.001]
  • [Cites] Med Hypotheses. 1980 Feb;6(2):145-92 [6993886.001]
  • [Cites] Biochemistry. 1997 Feb 4;36(5):1123-8 [9033403.001]
  • [Cites] Clin Exp Metastasis. 1994 Nov;12(6):357-67 [7923988.001]
  • [Cites] Gene. 1985;34(2-3):357-62 [2989113.001]
  • [Cites] Anat Rec. 1964 Jul;149:425-41 [14208987.001]
  • [Cites] Lancet. 1974 Aug 17;2(7877):382-4 [4137344.001]
  • [Cites] Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1505-9 [7878009.001]
  • [Cites] Blood. 1988 May;71(5):1475-9 [3359049.001]
  • [Cites] J Biol Chem. 1995 Jan 27;270(4):1785-90 [7530248.001]
  • [Cites] Semin Oncol. 2000 Jun;27(3):362-74 [10864223.001]
  • [Cites] J Exp Med. 1978 Jun 1;147(6):1584-95 [567240.001]
  • [Cites] Cancer Res. 1949 Jan;9(1):61-4 [18110414.001]
  • [Cites] Gan No Rinsho. 1972 Apr;18(4):285-9 [4337719.001]
  • [Cites] Blood. 2000 Nov 15;96(10):3302-9 [11071621.001]
  • [Cites] Science. 1964 Jan 10;143(3602):105-10 [14075717.001]
  • [Cites] Blood. 1985 Nov;66(5):1028-34 [2413926.001]
  • [Cites] Clin Exp Metastasis. 2000;18(1):57-60 [11206839.001]
  • [Cites] Ann N Y Acad Sci. 1992 Dec 4;667:101-11 [1309029.001]
  • [Cites] Thromb Haemost. 1997 May;77(5):894-900 [9184399.001]
  • [Cites] Semin Thromb Hemost. 1998;24(2):93-109 [9579631.001]
  • [Cites] Ann Med Exp Biol Fenn. 1956;34(Suppl 9):1-81 [13411709.001]
  • [Cites] J Clin Oncol. 1997 Jun;15(6):2403-13 [9196156.001]
  • [Cites] J Biol Chem. 1997 Feb 21;272(8):5360-6 [9030612.001]
  • [Cites] J Gen Physiol. 1945 Mar 20;28(4):363-83 [19873427.001]
  • [Cites] J Natl Cancer Inst. 1992 May 20;84(10):797-803 [1573668.001]
  • (PMID = 15554391.001).
  • [ISSN] 0262-0898
  • [Journal-full-title] Clinical & experimental metastasis
  • [ISO-abbreviation] Clin. Exp. Metastasis
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / 1 R43 CA 099258; United States / NCI NIH HHS / CA / 1 R43 CA 103563
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; 147336-22-9 / Green Fluorescent Proteins; B76N6SBZ8R / gemcitabine; EC 3.4.- / Streptokinase
  •  go-up   go-down






Advertisement