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Items 1 to 29 of about 29
3. Bekki J, Katayama S, Orihashi N, Nakagi H, Yamada A: [A case of recurrent lung cancer successfully treated using ambulatory chemotherapy with vinorelbine]. Gan To Kagaku Ryoho; 2002 Mar;29(3):431-4
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  • [Title] [A case of recurrent lung cancer successfully treated using ambulatory chemotherapy with vinorelbine].
  • She had previously suffered from stage IA lung adenocarcinoma and undergone a right upper lobe resection.
  • After 7 years, she complained of coughing and right chest pain.
  • Right pleural effusion and tumor mass shadow/lymph node swelling on the surgical margin of a right bronchus were found.
  • Combination chemotherapy with cisplatin (CDDP) and docetaxel (TXT) failed to produce an antitumor effect.
  • The treatment was changed to ambulatory chemotherapy with vinorelbine (VNB) at 20 mg/m2 weekly.
  • As VNB is easy to administer, it will be applicable in ambulatory chemotherapy administered with consideration of the patients quality of life.
  • [MeSH-major] Adenocarcinoma / drug therapy. Ambulatory Care. Antineoplastic Agents, Phytogenic / administration & dosage. Lung Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy. Vinblastine / administration & dosage. Vinblastine / analogs & derivatives
  • [MeSH-minor] Drug Administration Schedule. Female. Humans. Middle Aged

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  • (PMID = 11915734.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; 5V9KLZ54CY / Vinblastine; Q6C979R91Y / vinorelbine
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4. Tanimura S, Tsutsumi K, Okura M, Tanaka N, Yamamoto H, Honma K, Aida Y: [Successful removal of T4 lung cancer with left atrial invasion after induction chemotherapy]. Kyobu Geka; 2005 Oct;58(11):988-91
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  • [Title] [Successful removal of T4 lung cancer with left atrial invasion after induction chemotherapy].
  • The chest X-ray revealed a large mass shadow in the right lower lobe.
  • Massive tumor extending into the left atrium was diagnosed by computed tomography (CT).
  • The effect of the chemotherapy was complete response, enabling the surgical treatment.
  • The right pneumonectomy with partial resection of the left atrium was performed by using vascular clamp.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Squamous Cell / pathology. Heart Neoplasms / pathology. Lung Neoplasms / pathology. Pneumonectomy
  • [MeSH-minor] Cardiac Surgical Procedures. Cisplatin / administration & dosage. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Drug Administration Schedule. Heart Atria. Humans. Male. Middle Aged. Neoplasm Invasiveness. Paclitaxel / administration & dosage

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  • (PMID = 16235848.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 17
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5. Lazarevic V, Cemerikic-Martinovic V, Suvajdzic N, Subotic D, Colovic M: Diffuse primary plasmacytoma of the lung. Haematologia (Budap); 2001;31(2):161-5
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  • [Title] Diffuse primary plasmacytoma of the lung.
  • Primary plasmacytoma of the lung is a rare tumor, thus presenting a diagnostic challenge to the clinician.
  • The main finding on plain chest radiography was a diffuse infiltration of pulmonary parenchyma in the lower parts of both lungs and in the middle part of the right lung.
  • The histology of the open lung biopsy of the right middle lobe revealed massive and diffuse infiltration by well differentiated plasma cells with extracellular deposits of amyloid.
  • A skeletal survey and bone marrow biopsy specimen excluded a disseminated disease and a diagnosis of extramedullary plasmacytoma was made.
  • The patient was considered for VI courses of VMCP chemotherapy after which a complete regression on chest roentgenography was evident.
  • Almost five years after the diagnosis the patient is still alive without any evidence of disease recurrence or dissemination.
  • [MeSH-major] Lung Neoplasms / pathology. Plasmacytoma / pathology
  • [MeSH-minor] Aged. Amyloid / metabolism. Disease-Free Survival. Humans. Male. Neoplasm Invasiveness / pathology

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  • (PMID = 11583028.001).
  • [ISSN] 0017-6559
  • [Journal-full-title] Haematologia
  • [ISO-abbreviation] Haematologia (Budap)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Amyloid; 0 / amyloid protein AR, human
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6. Yokoo H, Kamiyama T, Nakanishi K, Tahara M, Fukumori D, Kamachi H, Matsushita M, Todo S: [A successful case of S-1 chemotherapy for bilateral pulmonary recurrence of hepatocellular carcinoma long after hepatectomy]. Gan To Kagaku Ryoho; 2010 Mar;37(3):483-5
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  • [Title] [A successful case of S-1 chemotherapy for bilateral pulmonary recurrence of hepatocellular carcinoma long after hepatectomy].
  • The treatment for hepatocellular carcinoma with distant metastasis remains unclear.
  • We experienced a successful case of S-1 chemotherapy for bilateral pulmonary recurrence of hepatocellular carcinoma following hepatectomy after gaining chemoresistance through pretreatment.
  • A 62-year-old man underwent extended right hepatectomy for hepatocellular carcinoma occupying the whole right lobe.
  • Pharmacokinetic modulation chemotherapy (PMC) was performed after treatment of UFT, and stable disease status for 24 months was achieved.
  • The present case suggests that S-1 chemotherapy may be useful for hepatocellular carcinoma with distant metastasis.
  • [MeSH-major] Carcinoma, Hepatocellular / pathology. Liver Neoplasms / pathology. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Oxonic Acid / therapeutic use. Tegafur / therapeutic use
  • [MeSH-minor] Administration, Oral. Drug Combinations. Hepatectomy. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Time Factors

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  • (PMID = 20332688.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid
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7. Old SE, Gilligan D, Balan KK, Coulden RA: Complete pathological response to chemotherapy for non-small cell lung cancer demonstrated by gamma camera positron emission tomography. Clin Oncol (R Coll Radiol); 2000;12(1):53-5
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  • [Title] Complete pathological response to chemotherapy for non-small cell lung cancer demonstrated by gamma camera positron emission tomography.
  • We report the case history of a 61-year-old female smoker who presented with an inoperable T2N2M0 squamous cell carcinoma of the right upper lobe bronchus.
  • This was staged by computed tomography (CT), positron emission tomography (PET) using a modified dual-headed gamma camera, and mediastinoscopy.
  • She then underwent three cycles of cisplatin-containing chemotherapy.
  • After the chemotherapy, CT demonstrated a residual 10 mm mass in the right upper lobe and a considerable reduction in size of the mediastinal lymphadenopathy.
  • At right upper lobectomy a complete pathological response was confirmed.
  • We discuss PET, the potential new applications of gamma camera technology, and the use of cisplatin-containing chemotherapy in non-small cell lung cancer.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Non-Small-Cell Lung / drug therapy. Lung Neoplasms / drug therapy. Tomography, Emission-Computed, Single-Photon / methods
  • [MeSH-minor] Cisplatin / administration & dosage. Female. Humans. Middle Aged. Neoplasm Staging / methods. Radiography. Treatment Outcome

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  • (PMID = 10749021.001).
  • [ISSN] 0936-6555
  • [Journal-full-title] Clinical oncology (Royal College of Radiologists (Great Britain))
  • [ISO-abbreviation] Clin Oncol (R Coll Radiol)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin
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8. Kurai J, Sako T, Miyata M, Matsumoto S, Nakanishi H, Makino H, Yasuda K, Burioka N, Hitsuda Y, Shimizu E: [A case with advanced non-small cell lung cancer showing long-term partial response to weekly chemotherapy with paclitaxel in outpatient treatment]. Gan To Kagaku Ryoho; 2003 Sep;30(9):1321-5
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  • [Title] [A case with advanced non-small cell lung cancer showing long-term partial response to weekly chemotherapy with paclitaxel in outpatient treatment].
  • A chest X-ray and CT showed a large pulmonary nodule in the right lower lobe.
  • A percutaneous transthoracic fine needle aspiration biopsy under computed tomographic guidance revealed an advanced lung cancer (adenocarcinoma T4N3M1 Stage IV).
  • He was treated with chemotherapy of weekly paclitaxel as an outpatient because he desired to continue working.
  • After the chemotherapy, good partial response of all lesions was achieved.
  • The regimen of weekly paclitaxel is useful and improves QOL of patients who desire to have outpatient treatment.
  • [MeSH-major] Adenocarcinoma / drug therapy. Ambulatory Care. Antineoplastic Agents, Phytogenic / administration & dosage. Lung Neoplasms / drug therapy. Paclitaxel / administration & dosage
  • [MeSH-minor] Drug Administration Schedule. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 14518414.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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9. Uçgun I, Akçayir Sahin I, Metintaş M, Alataş F, Erginel S, Dündar E: [Synchronous primary lung cancers: due to the four cases]. Tuberk Toraks; 2004;52(3):262-7
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  • [Title] [Synchronous primary lung cancers: due to the four cases].
  • If two primary lung cancers are present in the same time, it diagnosed as synchronous lung cancer.
  • It constitutes 0.1-1.6% of all lung cancers.
  • In this report, we described four cases diagnosed synchronous multiple primary lung cancers (MPLC) in between June 1999 and May 2002.
  • Histology of lung cancers was squamous-adeno in two cases, squamous-small cell lung cancer in one case, and squamous-squamous in two cases.
  • Lesion of second primary lung cancer was unable to seen in two patient's chest X-ray.
  • Their lesions were seen by computerized tomography in one case, and by bronchoscope only in the other case.
  • Lesion site was left lower lobe, right lower lobe, right middle lobe, and left upper lobe (25% for each).
  • Diagnosis of lung cancer was made by transthoracic needle biopsy in three lesion, and made by bronchoscopic biopsy in other lesions.
  • While it is recommended that, all of MPLC lesions were staged separately and treated surgically, due to the advanced age, presence of small cell lung cancer, and inadequate post-operative respiratory reserve, surgical treatment could not apply to these patients and they received chemotherapy.
  • Due to the this report, we emphasized that diagnostic procedures should be done separately for each lesions in patients who had more than one lesion, and treatment should plane according to these results.
  • [MeSH-major] Lung Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / drug therapy. Adenocarcinoma / radiography. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bronchoscopy. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / drug therapy. Carcinoma, Small Cell / radiography. Diagnosis, Differential. Fatal Outcome. Humans. Male. Middle Aged. Neoplasm Staging. Neoplasms, Squamous Cell / diagnosis. Neoplasms, Squamous Cell / drug therapy. Neoplasms, Squamous Cell / radiography. Smoking / adverse effects. Tomography, X-Ray Computed

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  • (PMID = 15351940.001).
  • [ISSN] 0494-1373
  • [Journal-full-title] Tüberküloz ve toraks
  • [ISO-abbreviation] Tuberk Toraks
  • [Language] tur
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Turkey
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10. Okagawa T, Uchida T, Suyama M: [A case of postoperative recurrent lung cancer with long survival due to gefitinib efficacy]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1841-3
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  • [Title] [A case of postoperative recurrent lung cancer with long survival due to gefitinib efficacy].
  • A 70-year-old woman underwent a right middle lobectomy and partial resection of right upper lobe for lung cancer.
  • About 6 years after the operation, the serum CEA level increased and chest CT revealed right pleural dissemination and right pleural effusion.
  • We diagnosed it as a recurrence of the lung cancer.
  • Although we recommended chemotherapy, she hesitated and went without treatment for about 1 year.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Agents / therapeutic use. Lung Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy. Quinazolines / therapeutic use
  • [MeSH-minor] Aged. Carcinoembryonic Antigen / blood. Drug Administration Schedule. Female. Humans. Survivors

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  • (PMID = 18030020.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Carcinoembryonic Antigen; 0 / Quinazolines; S65743JHBS / gefitinib
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11. Takahashi T, Sakamoto J, Kosaka S: [Metastatic lung tumor from uterine leiomyosarcoma; report of a case]. Kyobu Geka; 2008 Jul;61(7):595-8
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  • [Title] [Metastatic lung tumor from uterine leiomyosarcoma; report of a case].
  • Endometrial leimyosarcoma is rare neoplasm of all the uterine malignancies.
  • Following chemotherapy of cisplatin, ifomide and pirarubicine, right hepatectomy was performed.
  • About 12 years after the hysterectomy, a metastatic lesion appeared in the right lower lung field and right S6 segmentectomy was performed.
  • About 15 months after the pulmonary resection, another metastatic lesion appeared in the remaining right lower lobe.
  • The mass grew so rapidly with involvement to adjacent organs that pericardial resection was necessary with completion right lower lobectomy.
  • Postoperative chemotherapy was performed with the same regimen as previously performed.
  • About 10 months after the second pulmonary resection, she died due to dissemination in the right haemithorax and malignant pericardial effusion.
  • Careful follow up after the surgery for the uterine leiomyosarcoma is recommended because metastatic leiomyosarcoma possibly appears even after a long interval, and its progress can be so intensive that adjuvant chemotherapy is necessary if it can not be treated surgically alone.
  • [MeSH-major] Endometrial Neoplasms / pathology. Leiomyosarcoma / pathology. Leiomyosarcoma / secondary. Lung Neoplasms / secondary
  • [MeSH-minor] Female. Humans. Middle Aged

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  • (PMID = 18616110.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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12. Iwata T, Inoue K, Mizuguchi S, Morita R, Tsukioka T, Tanaka H, Suehiro S: Extended resection of primary lung cancer directly invading the liver. Respirology; 2008 Jun;13(4):619-20
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  • [Title] Extended resection of primary lung cancer directly invading the liver.
  • Chest CT revealed a mass of 6 cm diameter in the right lower lobe.
  • To alleviate local symptoms and for possible cure with adjuvant chemotherapy and radiotherapy, standard right lower lobectomy and mediastinal dissection were carried out, followed by combined resection of the diaphragm and posterior superior segmentectomy of the liver.
  • Eleven months postoperatively, the patient was alive but had a metastatic lesion in the other lobe of the liver which reduced in size following chemotherapy.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Liver Neoplasms / secondary. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Thoracic Surgery, Video-Assisted / methods
  • [MeSH-minor] Diaphragm / surgery. Female. Hepatectomy. Humans. Mediastinum / surgery. Middle Aged. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 18494953.001).
  • [ISSN] 1440-1843
  • [Journal-full-title] Respirology (Carlton, Vic.)
  • [ISO-abbreviation] Respirology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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13. Al-Sarraf N, Aziz R, Gately K, Lucey J, Wilson L, McGovern E, Young V: Pattern and predictors of occult mediastinal lymph node involvement in non-small cell lung cancer patients with negative mediastinal uptake on positron emission tomography. Eur J Cardiothorac Surg; 2008 Jan;33(1):104-9
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  • [Title] Pattern and predictors of occult mediastinal lymph node involvement in non-small cell lung cancer patients with negative mediastinal uptake on positron emission tomography.
  • OBJECTIVE: We sought to assess the incidence, pattern and predictors of occult mediastinal lymph node involvement (N2) in non-small cell lung cancer patients with negative mediastinal uptake of 2-deoxy-2-[(18)F]-fluoro-d-glucose ((18)FDG) on integrated positron emission tomography-computerised tomography (PET-CT).
  • All patients had preoperative PET-CT prior to lung resection as an adjunct to a dedicated chest CT.
  • Diabetic patients, patients who received neoadjuvant chemotherapy and those with positive mediastinal nodes on PET-CT (N2/N3) were excluded from this study.
  • In univariate analysis, the following were significant predictors of occult N2 disease: centrally located tumours (P=0.049), right upper lobe tumours (P=0.04), enlarged lymph nodes (>1cm) on CT (P=0.048) and PET positive uptake in N1 nodes (P=0.006).
  • In multivariate analysis, the following were independent predictors of occult N2 disease: centrally located tumours, right upper lobe tumours and PET positive uptake in N1 nodes (P<0.05).
  • Patients with the following: centrally located tumours, right upper lobe tumours and positive N1 nodes on PET should have preoperative cervical mediastinoscopy to rule out N2 nodal involvement, especially in ATS stations 7 and 4 as the incidence of occult nodal metastasis in these nodes is high.
  • This study has potential implications in decision-making and planning best treatment approach.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Lung Neoplasms / radionuclide imaging. Lymph Nodes / radionuclide imaging. Mediastinoscopy / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Cohort Studies. Female. Humans. Male. Mediastinum. Middle Aged. Neoplasm Staging. Positron-Emission Tomography / methods. Predictive Value of Tests. Treatment Outcome

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  • (PMID = 17977738.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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14. Liu K, Chen HL, You QS, Huang JF, Wang H: [Clinical analysis of skip N2 metastases in stage IIIA non-small cell lung cancer]. Ai Zheng; 2009 Jul;28(7):725-9
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  • [Title] [Clinical analysis of skip N2 metastases in stage IIIA non-small cell lung cancer].
  • BACKGROUND AND OBJECTIVE: Clinical characteristics of skip N2 metastasis of stage IIIA non-small cell lung cancer (NSCLC) are not clear.
  • Moreover, the relationship between the primary tumor location and N2 positive lymph nodes were described as follows: right upper lobe cancer displayed skip-N2 nodal metastasis mostly in the 3rd and 4th station (85.7%), right middle lobe mostly in the 7th station(75.0%), right lower lobe mostly in the 3rd and 7th station(81.0%), left upper lobe mostly in the 5th and 6th station(80.0%), and left lower lobe mostly in the 7th station (65.0%).
  • Survival analysis showed that skip N2 metastasis was an independent risk factor of stage IIIA NSCLC in addition to tumor size, histology, type of resection, adjuvant chemotherapy and radiotherapy.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / pathology. Lung Neoplasms / pathology. Lymph Nodes / pathology
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Lung. Lymph Node Excision. Lymphatic Metastasis. Male. Mediastinum. Middle Aged. Neoplasm Staging. Pneumonectomy / methods. Proportional Hazards Models. Radiotherapy, Adjuvant. Retrospective Studies. Risk Factors. Survival Rate

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  • (PMID = 19624899.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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15. DeArmond DT, Mahtabifard A, Fuller CB, McKenna RJ Jr: Photodynamic therapy followed by thoracoscopic sleeve lobectomy for locally advanced lung cancer. Ann Thorac Surg; 2008 May;85(5):e24-6
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  • [Title] Photodynamic therapy followed by thoracoscopic sleeve lobectomy for locally advanced lung cancer.
  • Photodynamic therapy is an effective technique for debulking endobronchial tumors over an acceptably short time-course; however, to be effective, numerous treatment cycles may be required to achieve the desired results.
  • We present a case in which photodynamic therapy was used with curative intent to downsize an obstructing endobronchial non-small cell lung cancer in advance of resection via video-assisted thoracoscopic surgery with right upper lobe sleeve lobectomy.
  • [MeSH-major] Carcinoma, Adenosquamous / drug therapy. Carcinoma, Adenosquamous / surgery. Lung Neoplasms / drug therapy. Lung Neoplasms / surgery. Neoadjuvant Therapy. Photochemotherapy / methods. Pneumonectomy / methods. Thoracic Surgery, Video-Assisted / methods
  • [MeSH-minor] Bronchoscopy. Combined Modality Therapy. Debridement / methods. Female. Humans. Lung / pathology. Lymph Node Excision. Middle Aged. Neoplasm Staging. Prognosis. Tomography, X-Ray Computed

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  • (PMID = 18442525.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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16. Schaeffer CJ, Minai OA, Sharma N, Kanne JP, Mohammed TL: Inflammatory myofibroblastic tumor of the lung: recurrence after steroid treatment. J Thorac Imaging; 2008 Aug;23(3):191-3
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  • [Title] Inflammatory myofibroblastic tumor of the lung: recurrence after steroid treatment.
  • We report a case of a patient with inflammatory myofibroblastic tumor of the lung, which recurred after steroid treatment.
  • The diagnosis of the tumor was confirmed by a core needle lung biopsy and pathology.
  • The patient was initiated on steroid therapy, which on complete response was slowly tapered and discontinued.
  • Chest radiography and computed tomography scans depicted recurrence at the tumor resection site in the right lobe of lung and a new tumor in the left lower lobe.
  • Restarting the steroid therapy, led to regression of the tumors at both sites.
  • This is a rare case of inflammatory myofibroblastic tumor recurring poststeroid therapy and adds to the current clinical knowledge about this peculiar manifestation of this disease entity.
  • [MeSH-major] Granuloma, Plasma Cell / drug therapy. Inflammation. Lung / radiography. Lung Neoplasms / drug therapy. Neoplasm Recurrence, Local. Neoplasms, Muscle Tissue / drug therapy. Steroids / therapeutic use
  • [MeSH-minor] Dyspnea / complications. Humans. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18728547.001).
  • [ISSN] 1536-0237
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Steroids
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17. Shimato S, Wakabayashi T, Mizuno M, Nakahara N, Hatano H, Natsume A, Ishii D, Hasegawa Y, Hyodo I, Nagasaka T, Yoshida J: Brain metastases from apocrine carcinoma of the scalp: case report. J Neurooncol; 2006 May;77(3):285-9
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  • Apocrine carcinoma is an extremely rare malignant neoplasm that occurs most frequently in the axilla.
  • The brain metastases appeared in spite of several regimens of chemotherapy for lung metastases for two years.
  • The tumor in the right frontal lobe was successfully operated.
  • However, the small tumor in the right occipital lobe was not cured by gamma knife surgery, and eventually required second operation.
  • The operation had contributed to his neurologically independent life for about one year until he died for gradual progression of lung metastases.
  • [MeSH-major] Apocrine Glands / pathology. Brain Neoplasms / secondary. Carcinoma / secondary. Lung Neoplasms / secondary. Skin Neoplasms / pathology
  • [MeSH-minor] Fatal Outcome. Frontal Lobe / pathology. Frontal Lobe / surgery. Humans. Male. Middle Aged. Occipital Lobe / pathology. Occipital Lobe / surgery. Scalp / pathology

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  • [Cites] J Cutan Pathol. 1984 Oct;11(5):437-49 [6096425.001]
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  • (PMID = 16314948.001).
  • [ISSN] 0167-594X
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Giannikaki E, Mantadakis E, Mamalaki E, Delides G, Samonis G: Metastatic uterine leiomyosarcoma coexisting with papillary carcinoma of the thyroid gland. Int J Gynecol Cancer; 2006 Jan-Feb;16(1):442-5
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  • We report a 54-year-old postmenopausal woman with uterine leiomyosarcoma, who presented with a single "cold" nodule in the right thyroid lobe 3 months after hysterectomy.
  • In a separate area of the thyroid, a 1.2-mm area of a malignant mesenchymal neoplasm with morphologic and immunohistochemical features of leiomyosarcoma existed.
  • Seven months after thyroidectomy the patient developed micronodular lung disease visible on successive chest computed tomography scans, consistent with metastatic disease from the primary uterine leiomyosarcoma that showed very good and prolonged response to chemotherapy.
  • [MeSH-major] Carcinoma, Papillary / pathology. Leiomyosarcoma / secondary. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Thyroid Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Humans. Hysterectomy / methods. Immunohistochemistry. Middle Aged. Neoplasm Staging. Postmenopause. Risk Assessment. Thyroidectomy. Treatment Outcome

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  • (PMID = 16445675.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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19. Suzuki M, Kojima T, Saito H, Nishiura Y, Kawakami Y: [A case of pulmonary embolic metastasis of choriocarcinoma presenting with multiple pulmonary infiltrative shadows]. Nihon Kokyuki Gakkai Zasshi; 2004 Jul;42(7):671-5
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  • Chest radiography and computed tomography showed bilateral multiple infiltrative shadows over the lung field.
  • After an initial diagnosis of pneumonia, antibiotics were administered, but the therapy failed to improve the symptoms and abnormalities observed on the chest radiograph.
  • In order to confirm the pathological diagnosis, video-assisted thoracoscopic lung biopsy was performed aiming at the right middle and lower lobes.
  • There were bleeding pulmonary infarctions in a biopsy specimen from the right middle lobe.
  • Atypical cells positive for human chorionic gonadotropin (hCG) proliferated in the pulmonary arteries, and so a diagnosis of pulmonary embolic metastasis of choriocarcinoma was made.
  • After the diagnosis, it became clear that urine and serum hCG values were very high.
  • The patient has since received systemic chemotherapy in the gynecology unit at our hospital.
  • Pulmonary embolic metastasis of choriocarcinoma diagnosed by video-assisted thoracoscopic lung biopsy has never been reported in the literature.
  • However, early hCG measurement may have detected this syndrome in the earlier stages, and pulmonary metastasis of choriocarcinoma should be considered in the differential diagnosis of women with past pregnancy presenting with intractable multiple pulmonary shadows.
  • [MeSH-major] Choriocarcinoma / secondary. Lung / radiography. Lung Neoplasms / secondary. Neoplasms, Unknown Primary. Neoplastic Cells, Circulating / pathology
  • [MeSH-minor] Adult. Biopsy. Chorionic Gonadotropin / blood. Chorionic Gonadotropin / urine. Diagnosis, Differential. Female. Humans. Neoplasm Invasiveness. Thoracic Surgery, Video-Assisted

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  • (PMID = 15357272.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin
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20. Zhang LB, Sun YE, Yu CH, Liu Y: [Clinical diagnosis and surgical treatment of primary pulmonary lymphoma]. Zhonghua Wai Ke Za Zhi; 2006 Jan 15;44(2):97-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Clinical diagnosis and surgical treatment of primary pulmonary lymphoma].
  • OBJECTIVE: To study the clinical characteristics, the principles of diagnosis and surgical treatment for primary pulmonary lymphoma.
  • METHOD: Ten patients with primary pulmonary lymphoma were treated surgically and their clinical characteristics, the experiences of clinical diagnosis and surgical treatment were analyzed.
  • The tumors located in left upper lobe in 2, left lower lobe in 1, right upper lobe in 3, right middle lobe in 3 and right lower lobe in 1.
  • All cases with non-Hodgkin's lymphoma received regular chemotherapy (MOPP and ABVD scheme for 1 case with Hodgkin's disease respectively, CHOP for 8 cases with non-Hodgkin's lymphoma), and 3 cases received radiotherapy postoperatively.
  • RESULTS: Eight cases were non-Hodgkin's lymphoma (B-type) and 2 cases were Hodgkin's disease (mixed type) confirmed by pathological examination.
  • Two cases with non-Hodgkin's lymphoma (stage II 2E, B-cell, low-grade) and 2 cases with Hodgkin's disease (stage IE and II 2E, mixed type) died in 24, 32, 8 and 17 months postoperatively respectively.
  • CONCLUSIONS: Primary pulmonary lymphoma is a rare type of malignant lung neoplasm without special clinical features.
  • The preoperative diagnosis is difficult.
  • Treatment modalities include surgical treatment, radiotherapy and regular chemotherapy postoperatively.
  • [MeSH-major] Lung Neoplasms / diagnosis. Lung Neoplasms / surgery. Lymphoma / diagnosis. Lymphoma / surgery
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Lymph Node Excision. Male. Middle Aged. Pneumonectomy / methods. Retrospective Studies

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  • (PMID = 16620666.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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21. Chen CH, Chen TC, Huang WC, Chen TY, Liu HC: An unusual successfully treated case of pulmonary yolk sac tumor. Ann Thorac Surg; 2008 Feb;85(2):656-8
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  • Extragonadal germ cell tumors are relatively rare, particularly malignant yolk sac tumors arising in the lung parenchyma.
  • We report a case of a huge malignant yolk sac tumor in the right middle lobe.
  • The patient was successfully treated with neoadjuvant chemotherapy followed by complete resection of the tumor.
  • [MeSH-major] Endodermal Sinus Tumor / surgery. Lung Neoplasms / surgery. Neoadjuvant Therapy. Pneumonectomy / methods
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Neoplasm Staging. Risk Assessment. Thoracotomy / methods. Treatment Outcome

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  • (PMID = 18222293.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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22. Bini A, Ansaloni L, Grani G, Grazia M, Pagani D, Stella F, Bazzocchi R: Pulmonary blastoma: report of two cases. Surg Today; 2001;31(5):438-42
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  • Physical examination revealed slightly significant findings, chest radiographs showed a large pulmonary mass, confirmed by computed tomography, and bronchoscopic biopsies were not diagnostic.
  • A left and right inferior lobectomy was performed and a diagnosis of CPBP was confirmed by histological examination.
  • In the first patient, local recurrence with multiple bilateral lung metastases was found 6 months later and despite chemotherapy, he died of respiratory failure 1 year after his operation.
  • In the second patient, a subcutaneous metastasis was found in the right subscapular region 2 months later, and a cerebral metastasis in the right posterior parietal lobe 4 months later.
  • We conclude that more aggressive and multidisciplinary treatment should be adopted for CBPB, and because of its low incidence, it is important to unify individual experiences in a central registry to gather as much information as possible regarding the biological and clinical features of this unusual disease.
  • [MeSH-major] Lung Neoplasms / surgery. Pulmonary Blastoma / surgery
  • [MeSH-minor] Aged. Fatal Outcome. Hemoptysis / etiology. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Prognosis. Smoking / adverse effects

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  • (PMID = 11381509.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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23. Takagi Y, Nakamura H, Miwa K, Adachi Y, Fujioka S, Haruki T, Taniguchi Y: A case of G-CSF-producing invasive apical cancer resected following preoperative adjuvant therapy. Thorac Cardiovasc Surg; 2010 Aug;58(5):304-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of G-CSF-producing invasive apical cancer resected following preoperative adjuvant therapy.
  • The patient was a 47-year-old male with the chief complaints of right shoulder pain and fever.
  • A 10-cm mass was found to be present in the right pulmonary apical region on chest X-ray examination.
  • The mass was diagnosed as a G-CSF-producing invasive apical cancer and the patient underwent chemoradiotherapy followed by right upper lobectomy with combined resection of the chest wall, and lymph node dissection.
  • A very small nodule was noted in the right frontal lobe on brain MRI before surgery, and the final diagnosis was pT3N0M1, stage IV lung adenocarcinoma.
  • For the brain metastasis, gamma knife treatment and chemotherapy were performed after surgery, and there was no recurrence during 16 months after surgery.
  • The prognosis for G-CSF-producing lung cancer and invasive apical cancer is poor.
  • This was a rare and difficult case of lung cancer showing both characteristics of lung cancer.
  • [MeSH-major] Adenocarcinoma / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Granulocyte Colony-Stimulating Factor / blood. Lung Neoplasms / therapy. Lymph Node Excision. Pneumonectomy
  • [MeSH-minor] Biopsy. Brain Neoplasms / secondary. Brain Neoplasms / therapy. Chemotherapy, Adjuvant. Humans. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Neoplasm Staging. Neurosurgical Procedures. Positron-Emission Tomography. Radiotherapy, Adjuvant. Thoracic Wall / pathology. Thoracic Wall / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • [Copyright] Copyright (c) Georg Thieme Verlag KG Stuttgart-New York.
  • (PMID = 20680910.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 143011-72-7 / Granulocyte Colony-Stimulating Factor
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24. Oshika Y, Matsukuma S, Hashimoto H, Takeo H, Sato K, Tanaka Y: Biphagic pulmonary blastoma with a lesion of yolk sac tumor. Gen Thorac Cardiovasc Surg; 2007 Jun;55(6):243-7
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  • The tumor was detected in the right upper lobe as a 10-cm mass.
  • The patient underwent right upper lobectomy and mediastinal lymph node dissection.
  • Adjuvant chemotherapy consisted of cisplatin and etoposide.
  • Local recurrence was disclosed 27 months after surgery, and radiation therapy was performed.
  • [MeSH-major] Endodermal Sinus Tumor / therapy. Lung Neoplasms / therapy. Pulmonary Blastoma / therapy
  • [MeSH-minor] Combined Modality Therapy. Humans. Lymph Node Excision. Male. Middle Aged. Neoplasm Recurrence, Local. Tomography, X-Ray Computed. alpha-Fetoproteins / analysis

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  • (PMID = 17642278.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
  • [Number-of-references] 10
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25. Kaneko H, Isogai K, Kondo M, Hosoi K, Asano T, Funato M, Kondo N: Autologous peripheral blood stem cell transplantation in a patient with relapsed pleuropulmonary blastoma. J Pediatr Hematol Oncol; 2006 Jun;28(6):383-5
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  • We present a 4-year-old girl with a tumor mass in the right hemithorax initially diagnosed as pneumoniae.
  • Tumor resection was performed and the histologic report indicated the diagnosis of PPB.
  • The patient received chemotherapy comprising vincristine, actinomycin D, doxorubicin, cisplatin, and cyclophosphamide.
  • Irradiation was performed with total 45 Gy at the right lower pulmonary lobe.
  • She relapsed 29 months later at the pleura between the right middle and lower pulmonary lobe.
  • Tumor resection and total 45 Gy of irradiation were performed again.
  • High-dose chemotherapy comprising cisplatin, adriamycin, and cyclophosphamide was performed followed by autologous peripheral blood stem cell transplantation (PBSCT).
  • Although it might be that the patient could have been cured with second surgery alone or by the surgery and subsequent chemotherapy, high-dose chemotherapy and PBSCT should be considered for the treatment of relapsed PPB.
  • [MeSH-major] Lung Neoplasms / therapy. Neoplasm Recurrence, Local / therapy. Peripheral Blood Stem Cell Transplantation. Pulmonary Blastoma / therapy
  • [MeSH-minor] Antineoplastic Agents / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Child, Preschool. Cisplatin / administration & dosage. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Dactinomycin / administration & dosage. Doxorubicin / administration & dosage. False Positive Reactions. Humans. Male. Pneumonia / diagnosis. Pneumonia / pathology. Prognosis. Transplantation, Autologous. Vincristine / administration & dosage


27. Kosaba S, Yamamoto K: [Carinal reconstruction with wide airway resection by a new technique]. Kyobu Geka; 2001 Jan;54(1):4-7
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  • A 61-year man with tracheal stenosis by tracheal cancer, 6 tracheal rings, 2 left bronchial rings, total right main bronchus, for which carina was resected and reconstructed by a new technique and for a 69 year man with lung cancer in right upper lobe, for which right upper-middle bilobectomy, S6 segmental resection and circumferential pulmonary artery resection were performed.
  • The tracea, left main bronchus, and right basal segment bronchus were anastomosed by new technique and the right main pulmonary artery and basal segment artery was anastomosed subsequent to chemotherapy.
  • The new reconstructive method of carina permits simple anastomosis, the possibility of carina reconstruction even in the case of wide airway resection and loss tension at the site of anastomosis.
  • [MeSH-minor] Aged. Anastomosis, Surgical / methods. Humans. Lung Neoplasms / surgery. Male. Middle Aged. Neoplasm Invasiveness. Pneumonectomy. Treatment Outcome

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  • (PMID = 11197908.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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28. Chen CS, Miller NR, Lane A, Eberhart C: Third cranial nerve palsy caused by intracranial extension of a sino-orbital natural killer T-cell lymphoma. J Neuroophthalmol; 2008 Mar;28(1):31-5
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  • A 53-year-old man with systemic lupus erythematosus who was receiving chronic low-dose prednisone treatment developed proptosis of the right eye.
  • Clinical and imaging manifestations resolved with a higher dose of prednisone, but when the prednisone dose was tapered, the patient developed a complete right third cranial nerve palsy.
  • Imaging showed return of the original lesion, now with intracranial extension and enhancement of the right third cranial nerve.
  • Biopsy of this lesion in its early stage may misleadingly suggest a primary inflammatory disorder because of a paucity of neoplastic cells, a large number of inflammatory cells recruited by the innate natural killer (NK) cell immune response, and extensive necrosis caused by angiodestructive tumor cells.
  • [MeSH-major] Frontal Lobe / pathology. Lymphoma, Extranodal NK-T-Cell / complications. Lymphoma, Extranodal NK-T-Cell / diagnosis. Oculomotor Nerve Diseases / etiology. Oculomotor Nerve Diseases / pathology. Orbit / pathology. Paranasal Sinuses / pathology
  • [MeSH-minor] Antigens, Neoplasm / analysis. Antigens, Neoplasm / immunology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Biomarkers, Tumor / immunology. Epstein-Barr Virus Infections / complications. Epstein-Barr Virus Infections / immunology. Fatal Outcome. Humans. Immunosuppressive Agents / therapeutic use. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Lupus Erythematosus, Systemic / complications. Lupus Erythematosus, Systemic / drug therapy. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness / pathology. Oculomotor Nerve / pathology. Oculomotor Nerve / physiopathology. Prednisone / therapeutic use. Radiotherapy. Tomography, X-Ray Computed. Treatment Failure

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  • (PMID = 18347456.001).
  • [ISSN] 1536-5166
  • [Journal-full-title] Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society
  • [ISO-abbreviation] J Neuroophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Immunosuppressive Agents; VB0R961HZT / Prednisone
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29. Hounkpati A, Marie I, Paillotin D, Muir JF, Cuvelier A: [Paraneoplastic sclerodermiform syndrome]. Rev Mal Respir; 2010 Mar;27(3):251-6
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  • INTRODUCTION: Despite the known association between scleroderma and cancer, the current systemic sclerosis classifications do not clearly identify paraneoplastic sclerodermiform syndrome or sclerodermiform syndrome secondary to cancer treatments.
  • Chest X-ray and CT-scan identified an irregular opacity in the right upper lobe with enlarged mediastinal lymph nodes.
  • A diagnosis of bronchial adenocarcinoma was made following mediastinoscopy and the patient was treated with neo-adjuvant chemotherapy and lobectomy.
  • After two cycles of treatment, his skin lesions had almost disappeared.
  • CONCLUSION: The presence of a sclerodermiform syndrome may suggest the existence of an underlying neoplasm.
  • In this case report, the skin lesions disappeared quickly after antineoplastic treatment.
  • [MeSH-major] Adenocarcinoma / complications. Lung Neoplasms / complications. Paraneoplastic Syndromes / etiology. Scleroderma, Systemic / etiology
  • [MeSH-minor] Humans. Male. Middle Aged

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  • [Copyright] Copyright 2010 SPLF. Published by Elsevier Masson SAS. All rights reserved.
  • (PMID = 20359618.001).
  • [ISSN] 1776-2588
  • [Journal-full-title] Revue des maladies respiratoires
  • [ISO-abbreviation] Rev Mal Respir
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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