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Items 1 to 27 of about 27
1. Takaya T, Takeuchi Y, Nakajima H, Nishiki-Kosaka S, Hata K, Kijima Y, Kita T, Ito M, Okamoto M, Nishikawa Y, Seo T, Takaoka R, Ohta K, Yodoi K, Kawashima S: Usefulness of transesophageal echocardiographic observation during chemotherapy for cardiac metastasis of non-Hodgkin lymphoma complicated with left ventricular diastolic collapse. J Cardiol; 2009 Jun;53(3):447-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Usefulness of transesophageal echocardiographic observation during chemotherapy for cardiac metastasis of non-Hodgkin lymphoma complicated with left ventricular diastolic collapse.
  • A 53-year-old man, who had been treated for penile origin diffuse large B cell type non-Hodgkin lymphoma (NHL), suffered from right femoral pain and dyspnea.
  • Positron emission tomography (PET) revealed abnormal accumulation in his right femur and cardiac segments.
  • Transthoracic echocardiography revealed massive localized pericardial effusion with the collapse of both ventricles and the mass-like echo in the left atrium.
  • In order to evaluate the effect of chemotherapy, we performed TEE and observed the precise changes of intra-cardiac tumor size.
  • We experienced a case of cardiac metastasis of NHL complicated with left ventricular diastolic collapse due to the massive localized pericardial effusion.
  • TEE is a useful tool to evaluate precisely the efficacy of chemotherapy for intra-cardiac tumors.
  • [MeSH-major] Drug Monitoring / methods. Echocardiography, Transesophageal. Heart Neoplasms / secondary. Heart Neoplasms / ultrasonography. Lymphoma, Large B-Cell, Diffuse / pathology. Lymphoma, Large B-Cell, Diffuse / ultrasonography
  • [MeSH-minor] Cardiac Tamponade / etiology. Cardiac Tamponade / ultrasonography. Heart Atria / ultrasonography. Heart Ventricles / ultrasonography. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Penile Neoplasms / pathology. Pericardial Effusion / etiology. Pericardial Effusion / ultrasonography. Treatment Outcome

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  • (PMID = 19477389.001).
  • [ISSN] 1876-4738
  • [Journal-full-title] Journal of cardiology
  • [ISO-abbreviation] J Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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2. Hsing CT, Oh SY, Lee S, Kwon HC, Kim SH, Park TH, Woo JS, Na SH, Kim HJ: Extraskeletal mesenchymal chondrosarcoma of the heart responded to systemic chemotherapy: a case report. Cancer Res Treat; 2007 Sep;39(3):131-3

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extraskeletal mesenchymal chondrosarcoma of the heart responded to systemic chemotherapy: a case report.
  • Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm of an extraskeletal origin, and this predominately occurs in the head and neck, and also in the lower extremities.
  • For the most part, the results of treatment for patients with this condition have been dismal.
  • In this study, we describe a case of cardiac mesenchymal chondrosarcoma that responded to chemotherapy following surgical biopsy.
  • Chest computed tomography revealed an ovoid-shaped mass in the posterior wall of the patient's left atrium.
  • The echocardiogram revealed a large ovoid-shaped immobile mass (11x6 cm(2)) in the pericardiac space, which was attached to the posterior wall of the left atrium.
  • Seven days later, a thoracotomy was performed for reduction and diagnosis of the cardiac mass.
  • The pathological diagnosis was extraskeletal mesenchymal chondrosarcoma of the heart..
  • Postoperative chemotherapy was performed for the huge remaining mass with a combined regimen of etoposide, ifosfamide and cisplatin.
  • Although cardiac mesenchymal chondrosarcoma has been reported to be chemotherapy-resistant with a short survival duration, chemotherapy may prove to be an effective treatment modality.

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  • [Cites] Int J Urol. 2006 Mar;13(3):285-6 [16643625.001]
  • [Cites] Ital Heart J. 2000 Jun;1(6):435-7 [10929746.001]
  • [Cites] Am J Emerg Med. 1996 May;14(3):285-7 [8639204.001]
  • [Cites] Jpn Circ J. 1997 Sep;61(9):795-7 [9293411.001]
  • (PMID = 19746223.001).
  • [ISSN] 1598-2998
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2739328
  • [Keywords] NOTNLM ; Extraskeletal / Heart / Mesenchymal chondrosarcoma
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3. Ogimoto A, Hamada M, Ohtsuka T, Hara Y, Shigematsu Y, Yokoyama A, Imagawa H, Kawachi K, Kito K, Higaki J: Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis. Intern Med; 2003 Sep;42(9):827-30
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  • [Title] Rapid progression of primary cardiac leiomyosarcoma with obstruction of the left ventricular outflow tract and mitral stenosis.
  • We report a 73-year-old woman with primary cardiac leiomyosarcoma in the left atrium and ventricle.
  • Obstruction of the left ventricular outflow tract and mitral stenosis were induced by the tumor.
  • She refused postoperative chemotherapy and radiotherapy, and died suddenly at home 89 days after surgery.
  • To our knowledge, this is the first observation of mitral stenosis concomitant with obstruction of the left ventricular outflow tract in a patient with primary cardiac leiomyosarcoma.
  • [MeSH-minor] Aged. Cardiac Surgical Procedures / methods. Echocardiography. Fatal Outcome. Female. Humans. Neoplasm Invasiveness. Tomography, X-Ray Computed. Treatment Refusal

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  • (PMID = 14518670.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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4. Okamoto K, Kato S, Katsuki S, Wada Y, Toyozumi Y, Morimatsu M, Aoyagi S, Imaizumi T: Malignant fibrous histiocytoma of the heart: case report and review of 46 cases in the literature. Intern Med; 2001 Dec;40(12):1222-6
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  • Echocardiography, magnetic resonance imaging, and angiography demonstrated a tumor arising from the posterior wall of the left atrium.
  • Neither chemotherapy nor irradiation was administered.
  • [MeSH-major] Heart Neoplasms / diagnosis. Histiocytoma, Benign Fibrous / diagnosis
  • [MeSH-minor] Age Factors. Fatal Outcome. Female. Humans. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Risk Factors. Sex Factors

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  • (PMID = 11813848.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 57
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5. Candeias CM, Luís I, Ribeiro J, Costa L, de Almeida LS, Gomes MM, Barreto L, Brito-Avô L, Ducla-Soares JL: Extended remission of metastatic epithelioid angiosarcoma of the heart with liposomal doxorubicin. BMJ Case Rep; 2010;2010

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is a rare and aggressive neoplasm that almost always has a short and fatal evolution.
  • By the time it produces symptoms it has usually progressed to a mass causing haemodynamic compromise.
  • Body computed tomography scan disclosed a solid mass in the left atrium.
  • The tumour was judged unresectable and the patient was treated with systemic chemotherapy, consisting of liposomal doxorubicin, which resulted in a complete clinical response.
  • The excellent clinical evolution of our patient verifies that liposomal doxorubicin may be effective in the treatment of these tumours and significantly prolong patients' lifespan.

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  • (PMID = 22347886.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027499
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6. Lin JN: Cardiac lymphoma with first manifestation of recurrent syncope-a case report and literature review. Int Med Case Rep J; 2010;3:1-6

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Before permanent pacemaker implantation was undertaken, transthoracic echocardiography revealed a solid mass infiltrating the left atrium and interatrial septum.
  • Transesophageal echocardiography proved cardiac neoplasm with biatrial infiltration.
  • Endomyocardial tissue biopsy was performed under angiography guide.
  • Pathology diagnosis unraveled large B-cell lymphoma.
  • Despite aggressive chemotherapy, the patient's condition worsened and he died 2 months later.

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  • (PMID = 23754880.001).
  • [ISSN] 1179-142X
  • [Journal-full-title] International medical case reports journal
  • [ISO-abbreviation] Int Med Case Rep J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3658218
  • [Keywords] NOTNLM ; complete atrioventricular block / primary cardiac lymphoma
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7. Centella T, Oliva E, García Andrade I, Lamas MJ, Epeldegui A: [A patient with cardiac angiosarcoma who survived for four years. Case report and literature review]. Rev Esp Cardiol; 2005 Mar;58(3):310-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We describe a 57-year-old woman with a diagnosis of primary cardiac angiosarcoma.
  • She underwent emergency surgery with a preoperative diagnosis of atrial myxoma, and pathological analysis confirmed the diagnosis of cardiac angiosarcoma.
  • Two years later she was readmitted to the hospital with recurrence of the tumor in the left atrium and involvement of the mitral valve.
  • Another operation was carried out for mitral valve and left atrial wall reconstruction with a bovine pericardial patch.
  • The mortality associated with primary cardiac neoplasm is very high, although aggressive treatment together with appropriate chemotherapy may significantly prolong patient's lifespan.
  • [MeSH-minor] Female. Humans. Middle Aged. Survivors. Time Factors

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  • (PMID = 15766456.001).
  • [ISSN] 0300-8932
  • [Journal-full-title] Revista española de cardiología
  • [ISO-abbreviation] Rev Esp Cardiol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 5
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8. Shimizu J, Ikeda C, Arano Y, Adachi I, Morishita M, Yamaguchi S, Ishikawa N, Watanabe G, Minato H: Advanced lung cancer invading the left atrium, treated with pneumonectomy combined with left atrium resection under cardiopulmonary bypass. Ann Thorac Cardiovasc Surg; 2010 Aug;16(4):286-90
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  • [Title] Advanced lung cancer invading the left atrium, treated with pneumonectomy combined with left atrium resection under cardiopulmonary bypass.
  • Based on a bronchoscopic biopsy, it was diagnosed at a nearby clinic as an advanced left lung cancer, and he was referred to our hospital.
  • Chest computed tomography (CT) scans demonstrated a giant mass of the left lower lobe, 14 × 12 cm in size, which appeared to have invaded the left atrium (LA).
  • The patient underwent left pneumonectomy combined with LA resection using cardiopulmonary bypass (CPB), without aortic clamping, through left posterolateral thoracotomy under hypothermia (32 °C).
  • His postoperative course was uneventful, and he received 2 courses of adjuvant chemotherapy.
  • If CPB is used, the tension of the LA is removed by blood extraction into the bypass, and bradycardia is induced by a reduction of body temperature, probably reducing the risk of clamp dislocation.
  • [MeSH-minor] Aged. Cardiac Surgical Procedures. Cardiopulmonary Bypass. Heart Atria / pathology. Humans. Male. Neoplasm Invasiveness. Pneumonectomy

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  • (PMID = 21057449.001).
  • [ISSN] 2186-1005
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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9. Garraud M, Margery J, Laborde F, Saint-Blancard P, David S, Bonardel G, Héno P: [Pulmonary vein leiomyosarcoma extending into the left atrium]. Rev Pneumol Clin; 2010 Oct;66(5):321-5
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  • [Title] [Pulmonary vein leiomyosarcoma extending into the left atrium].
  • Thoracic computed tomography and transoesophagal ultrasonographic examination of the heart suggested the diagnosis of a heart tumour revealed by the obstruction of the mitral valve and pulmonary oedema.
  • Emergency cardiac surgery revealed the mass to be a leiomyosarcoma, probably extending from the right inferior pulmonary vein and extending into the left atrium.
  • The patient underwent a second cardiac intervention involving lower right lobectomy followed by adjuvant chemotherapy with an ifosfamide-adriamycin combination.
  • This treatment failed to control the disease and a third cardiac intervention was necessary with second-line gemcitabine-paclitaxel adjuvant chemotherapy.
  • Further recurrences were observed with metastases first in the scalp and then in the spine and adrenal glands leading to the death of the patient 2 years after the diagnosis.
  • [MeSH-major] Heart Atria / pathology. Heart Neoplasms / pathology. Leiomyosarcoma / diagnosis. Pulmonary Veins / pathology. Vascular Neoplasms / diagnosis
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Echocardiography, Transesophageal. Fatal Outcome. Humans. Male. Military Personnel. Mitral Valve / pathology. Neoadjuvant Therapy. Neoplasm Recurrence, Local / pathology. Pulmonary Edema / diagnosis. Respiratory Insufficiency / diagnosis. Tomography, X-Ray Computed

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 21087728.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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10. Fahn W, Schlemmer M, Issels R, Uberfuhr P, Reichart B: [Leiomyosarcoma of the heart--interdisciplinary therapeutic approach of systemic chemotherapy and subsequent heart transplantation]. Dtsch Med Wochenschr; 2003 Sep 26;128(39):2005-8
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  • [Title] [Leiomyosarcoma of the heart--interdisciplinary therapeutic approach of systemic chemotherapy and subsequent heart transplantation].
  • [Transliterated title] Leiomyosarkom des Herzen--interdisziplinärer Therapieansatz mit systemischer Chemotherapie und anschliessender Herztransplantation.
  • Imaging tests demonstrated a tumor of maximally 7 cm diameter in the region of the left atrium.
  • SUBSEQUENT INVESTIGATION: Six weeks after surgical resection a rapidly growing tumor, maximally 7.5 cm in diameter, was visualized at the right lateral region of the left atrium.
  • TREATMENT AND COURSE: As part of a multimodal therapeutic approach he was given 6 cycles of chemotherapy (doxorubicin and ifosfamide), bringing about significant reduction of the tumor size.
  • No tumor recurrence or distal metastasis was seen during a follow-up period of 36 months.
  • The patient died from right heart failure with advanced pulmonary hypertension 45 months after the diagnosis had first been made, 37 months after the cardiac transplantation.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Heart Neoplasms. Heart Transplantation. Leiomyosarcoma
  • [MeSH-minor] Adult. Combined Modality Therapy. Doxorubicin / therapeutic use. Fatal Outcome. Heart Atria. Humans. Ifosfamide / therapeutic use. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / surgery. Pneumonectomy


11. Spaggiari L, D' Aiuto M, Veronesi G, Pelosi G, de Pas T, Catalano G, de Braud F: Extended pneumonectomy with partial resection of the left atrium, without cardiopulmonary bypass, for lung cancer. Ann Thorac Surg; 2005 Jan;79(1):234-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extended pneumonectomy with partial resection of the left atrium, without cardiopulmonary bypass, for lung cancer.
  • BACKGROUND: Extended pneumonectomy with partial resection of the left atrium for lung cancer is not frequently performed; therefore, its results remain controversial.
  • METHODS: From November 1996 to December 2003, 15 patients underwent extended pneumonectomy with partial resection of the left atrium for lung cancer, without cardiopulmonary bypass.
  • Nine patients (60%) underwent induction chemotherapy.
  • CONCLUSIONS: Extended pneumonectomy with partial resection of the left atrium for advanced lung cancer is a feasible procedure, with low postoperative morbidity and mortality.
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / mortality. Adenocarcinoma / surgery. Adult. Aged. Antineoplastic Agents / therapeutic use. Arrhythmias, Cardiac / epidemiology. Carcinoma, Squamous Cell / drug therapy. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / surgery. Cardiopulmonary Bypass. Combined Modality Therapy. Databases, Factual. Female. Humans. Length of Stay / statistics & numerical data. Life Tables. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Staging. Postoperative Complications / epidemiology. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 15620949.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 11
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12. Toda R, Yotsumoto G, Masuda H, Sakata R, Umekita Y: Surgical treatment of malignant fibrous histiocytoma in the left atrium and pulmonary veins: report of a case. Surg Today; 2002;32(3):270-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of malignant fibrous histiocytoma in the left atrium and pulmonary veins: report of a case.
  • This report describes the case of a 16-year-old boy who underwent surgical treatment of a cardiac malignant fibrous histiocytoma (MFH).
  • An ultracardiogram (UCG) revealed a tumor about 10cm in diameter, in the left atrium.
  • Extirpation of the left atrial tumor, including the part extending into the pulmonary veins, was performed under cardiopulmonary bypass.
  • Histological examination confirmed a diagnosis of MFH.
  • No adjuvant chemotherapy or radiotherapy was given.
  • While there has been no evidence of local recurrence or metastasis in the 9 months since his operation, strict follow-up is being done by UCG and computed tomography.
  • Therefore, we reviewed only the surgical cases of this type of cardiac tumor documented in the literature.
  • [MeSH-minor] Adolescent. Heart Atria. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Retrospective Studies

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  • (PMID = 11991516.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 39
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13. Tanimura S, Tsutsumi K, Okura M, Tanaka N, Yamamoto H, Honma K, Aida Y: [Successful removal of T4 lung cancer with left atrial invasion after induction chemotherapy]. Kyobu Geka; 2005 Oct;58(11):988-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Successful removal of T4 lung cancer with left atrial invasion after induction chemotherapy].
  • Massive tumor extending into the left atrium was diagnosed by computed tomography (CT).
  • The effect of the chemotherapy was complete response, enabling the surgical treatment.
  • The right pneumonectomy with partial resection of the left atrium was performed by using vascular clamp.
  • The defect of the left atrium could be sutured directly.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Squamous Cell / pathology. Heart Neoplasms / pathology. Lung Neoplasms / pathology. Pneumonectomy
  • [MeSH-minor] Cardiac Surgical Procedures. Cisplatin / administration & dosage. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Drug Administration Schedule. Heart Atria. Humans. Male. Middle Aged. Neoplasm Invasiveness. Paclitaxel / administration & dosage

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  • (PMID = 16235848.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 17
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14. Modi A, Lipnevicius A, Moorjani N, Haw M: Prolonged survival with left atrial spindle cell sarcoma. Interact Cardiovasc Thorac Surg; 2009 Jun;8(6):703-4
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  • [Title] Prolonged survival with left atrial spindle cell sarcoma.
  • Primary spindle cell sarcoma of the left atrium is a rare tumour.
  • Optimal treatment is to obtain complete surgical clearance of the tumour.
  • The prognosis of patients with a primary cardiac sarcoma is very poor because of their resistance to treatment with chemotherapy and radiotherapy.
  • Metastases and local recurrences are common despite optimal multimodality treatment.
  • This report describes a 48-year-old gentleman who underwent multiple surgeries to achieve an 11-year survival since the diagnosis.
  • [MeSH-major] Carcinoma / surgery. Cardiac Surgical Procedures. Heart Neoplasms / surgery. Neoplasm Recurrence, Local
  • [MeSH-minor] Heart Atria / pathology. Heart Atria / surgery. Humans. Male. Middle Aged. Neoplasm Invasiveness. Reoperation. Time Factors. Treatment Outcome

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  • (PMID = 19304772.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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15. Belmadani K, Amahzoune B, Selkane C, Boulahya A, el Fakir Y, al Bouzidi A, el Kirat A: [Invasive thymoma extending into the superior vena cava and the right atrium: a case report and review of the literature]. Ann Cardiol Angeiol (Paris); 2001 Jun;50(4):217-23
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  • [Title] [Invasive thymoma extending into the superior vena cava and the right atrium: a case report and review of the literature].
  • We report an invasive case of thymome to higher intracellar extension, right intraatrial and pleuropulmonary revealed by a syndrome undermines higher and a left pleurisy.
  • The transthoracic echocardiography supplemented by the echocardiography transoesophageal pose the cardiac diagnosis of tumor, and it is the thoracic tomodensitometry which highlights a tumoral process mediastinal of malignant pace invading the left inominal venous trunk, the higher vena cava and extending in the right auricle.
  • The diagnosis of certainty is carried by the endobronchial biopsy and the puncture tomodensitometric biopsy under control of the mediastinal mass after anatomopathological examination.
  • Under chemotherapy, the evolution over 18 months is marked by the absence of cardiovascular complications in spite of the non regression of the tumoral mass.
  • The surgery when it is possible, remains the principal therapeutic measurement which really proved reliable.
  • [MeSH-major] Heart Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Thymoma / diagnosis. Thymus Neoplasms / diagnosis. Vascular Neoplasms / diagnosis. Vena Cava, Superior
  • [MeSH-minor] Aged. Heart Atria. Humans. Male. Neoplasm Invasiveness

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  • (PMID = 12555596.001).
  • [ISSN] 0003-3928
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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16. Ratto GB, Costa R, Vassallo G, Alloisio A, Maineri P, Bruzzi P: Twelve-year experience with left atrial resection in the treatment of non-small cell lung cancer. Ann Thorac Surg; 2004 Jul;78(1):234-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Twelve-year experience with left atrial resection in the treatment of non-small cell lung cancer.
  • BACKGROUND: We retrospectively reviewed our 12-year experience in the surgical treatment of non-small cell lung cancer invading the left atrium.
  • METHODS: Nineteen consecutive patients with lung cancer invading the left atrium underwent surgery.
  • Three patients with N2 disease underwent induction chemotherapy.
  • RESULTS: Five-year survival was 14%, and the median survival time was 25 months.
  • The 3 patients with N2 disease who underwent induction chemotherapy were alive and disease-free at 30, 15, and 11 months from surgery.
  • Survival was not affected by histology, type of surgery, or completeness of resection.
  • CONCLUSIONS: In spite of the poor survival rates we report, the present experience suggests that more-favorable results could be expected by the routine preoperative use of positron emission tomographic scan staging, a more-extensive assessment of atrial invasion, the application of induction chemotherapy in patients with N2 disease, and postoperative chemoradiotherapy in patients with tumors abutting the atrial resection margin.
  • [MeSH-minor] Aged. Arrhythmias, Cardiac / epidemiology. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Combined Modality Therapy. Follow-Up Studies. Humans. Life Tables. Male. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Postoperative Complications / epidemiology. Radiotherapy, Adjuvant. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 15223435.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 17
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17. Sakai T, Kimura D, Tsushima T, Hatanaka R, Yamada Y, Fukuda I: [Assessment of surgical treatment for lung cancer with pericardial or left atrial invasion]. Kyobu Geka; 2010 May;63(5):360-3
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  • [Title] [Assessment of surgical treatment for lung cancer with pericardial or left atrial invasion].
  • We evaluated surgical results for the patients who underwent pulmonary resection combined with pericardial or left atrial resection due to locally advanced non-small cell lung cancer (NSCLC).
  • Seven patients who underwent pericardial resection (T3 group) and 4 patients who underwent resection of the left atrium (T4 group) were included in this study, and clinical findings and prognosis were evaluated.
  • Induction chemotherapy was performed in 75.0% of T4 group.
  • Extended resection of pericardium or left atrium for patients with N2 disease of NSCLC is not recommended.
  • When invasion to pericardium or left atrium is diagnosed during surgery, extended resection should be indicated in patient without N2 metastasis.
  • [MeSH-minor] Aged. Humans. Male. Neoplasm Invasiveness. Pneumonectomy

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  • (PMID = 20446602.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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18. Ishibashi N, Mitachi Y, Sugawara S, Shinozaki S, Miura M, Fukuju T, Katahira Y, Koyama K, Fujikawa N, Kato T, Murakami K: [A case of cardiac angiosarcoma successfully treated with docetaxel]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1849-52
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  • We report a case of angiosarcoma of the right atrium presenting superior vena cava syndrome.
  • Echocardiography, CT and MRI revealed a tumor arising in the anterior wall of the right atrium.
  • An open biopsy and left brachiocephalic vein-right atrium bypass grafting were performed.
  • The pathological diagnosis was angiosarcoma.
  • The patient agreed to chemotherapy with docetaxel, which is known to be often effective against angiosarcoma of the scalp or face.
  • The chemotherapy was suspended for 8 months because of neutropenia and general fatigue as side effects of docetaxel.
  • Following treatments with paclitaxel, IL-2 and CPT-11 were ineffective for the primary tumor and liver metastases.
  • He had long-term survival 31 months after the diagnosis.
  • An effective treatment for cardiac angiosarcoma has not yet been established.
  • Chemotherapy with docetaxel should be considered in the treatment of patients with cardiac angiosarcoma.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Heart Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Taxoids / therapeutic use
  • [MeSH-minor] Drug Administration Routes. Drug Resistance, Neoplasm. Heart Atria. Humans. Liver Neoplasms / secondary. Male. Middle Aged

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  • (PMID = 18030022.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Taxoids; 15H5577CQD / docetaxel
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19. Jimenez JF, Warren ET, Shroff RK, Stolz GA: Primary cardiac paraganglioma. J Ark Med Soc; 2005 Jun;101(12):362-4
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  • The neoplasm (4.7 cm in diameter) was surgically excised from the left posterior atrium.
  • Adriamycin-based adjuvant chemotherapy was administered.
  • [MeSH-minor] Antibiotics, Antineoplastic. Chemotherapy, Adjuvant. Doxorubicin / therapeutic use. Follow-Up Studies. Heart Atria. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 15948504.001).
  • [ISSN] 0004-1858
  • [Journal-full-title] The Journal of the Arkansas Medical Society
  • [ISO-abbreviation] J Ark Med Soc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 80168379AG / Doxorubicin
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20. Abe H, Minagawa T, Ishiwara R, Uchigasaki S, Takeda F: [Multiple recurrent cardiac myxomas]. Kyobu Geka; 2009 Mar;62(3):198-201

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Echocardiography revealed new masses in the left atrium and the right ventricle.
  • Both tumors were removed surgically and subsequently treated with adjuvant chemotherapy.
  • [MeSH-major] Heart Neoplasms / surgery. Myxoma / surgery. Neoplasm Recurrence, Local
  • [MeSH-minor] Cardiac Surgical Procedures. Chemotherapy, Adjuvant. Heart Atria. Heart Ventricles. Humans. Male. Middle Aged. Reconstructive Surgical Procedures. Treatment Outcome

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  • (PMID = 19280949.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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21. Krieghoff B, Skuballa A, Leonhardt P, Mohr FW, Wittekind C, Bossert T, Achatzy R: [Primary synovial sarcoma of the lung - a rare tumor]. Zentralbl Chir; 2002 Aug;127(8):716-9
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  • Finally, because of recurrent hemoptysis a central tumor of mesenchymal origin of the left lower lobe was diagnosed by bronchoscopy.
  • The invasion of the left atrium as far as to the mitral valve was diagnosed by MRT.
  • The partial excision of the left atrium required plastic reconstruction.
  • In the postoperative course the patient underwent chemo-therapy, 6 cycles adriablastine/ifosfamid.
  • The patient refused further radio- or chemotherapy and died 14 months after the operation.
  • Because of the small number of cases therapeutic strategy conceptions do not exist.
  • [MeSH-minor] Adult. Bronchoscopy. Diagnosis, Differential. Diagnostic Imaging. Humans. Lung / pathology. Male. Neoplasm Staging. Pneumonectomy

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  • (PMID = 12200737.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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22. Kinebuchi Y, Ogawa T, Kato H, Igawa Y, Nishizawa O, Miyagawa S: Testicular cancer with tumor thrombus extending to the inferior vena cava successfully removed using veno-venous bypass: a case report. Int J Urol; 2007 May;14(5):458-60
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  • A 33-year-old man with a left testicular tumor was referred to Shinshu University Hospital for advanced therapy.
  • Radiographic imaging revealed multiple metastases in the retroperitoneal lymph nodes (RPLN) and bilateral lungs, as well as tumor thrombus that extended from the left renal vein to the inferior vena cava (IVC) adjacent to the right atrium.
  • After orchidectomy, a diagnosis of embryonal carcinoma was made with a clinical stage of T1N2M1bS3, which has a poor prognosis, based on the International Germ Cell Cancer Collaborative Group consensus.
  • After eight courses of chemotherapy, the patient's tumor markers normalized and the lung metastases disappeared, but the RPLN and tumor thrombus remained.
  • [MeSH-minor] Adult. Anastomosis, Surgical / methods. Humans. Male. Neoplasm Invasiveness. Remission Induction. Renal Artery / surgery. Renal Veins / surgery. Vascular Surgical Procedures / methods

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  • (PMID = 17511736.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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23. Park BJ, Bacchetta M, Bains MS, Downey RJ, Flores R, Rusch VW, Girardi LN: Surgical management of thoracic malignancies invading the heart or great vessels. Ann Thorac Surg; 2004 Sep;78(3):1024-30
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  • We reviewed our experience of 10 patients treated surgically, either primarily or as a component of multimodality therapy, to assess feasibility and results.
  • RESULTS: Histologic diagnoses included soft tissue sarcoma (n = 7), squamous cell carcinoma (n = 1), malignant thymoma (n = 1), and mediastinal teratoma (n = 1).
  • Three patients underwent induction chemotherapy.
  • Structures resected included superior vena cava (n = 5), left atrium (n = 4), right atrium (n = 2), descending aorta (n = 1), and main pulmonary artery (n = 1).
  • Six patients underwent postoperative systemic therapy.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Heart Neoplasms / surgery. Neoplasm Invasiveness / pathology. Sarcoma / surgery. Teratoma / surgery. Thymoma / surgery. Vascular Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Aorta, Thoracic / pathology. Cardiopulmonary Bypass. Chemotherapy, Adjuvant. Echocardiography, Transesophageal. Female. Follow-Up Studies. Heart Atria / pathology. Humans. Length of Stay. Male. Middle Aged. Pulmonary Artery / pathology. Retrospective Studies. Survival Rate. Thymus Neoplasms / diagnosis. Thymus Neoplasms / pathology. Tomography, X-Ray Computed. Treatment Outcome. Vena Cava, Superior / pathology

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  • (PMID = 15337042.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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24. Doddoli C, Rollet G, Thomas P, Ghez O, Serée Y, Giudicelli R, Fuentes P: Is lung cancer surgery justified in patients with direct mediastinal invasion? Eur J Cardiothorac Surg; 2001 Aug;20(2):339-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To assess the results of the surgical treatment of patients with stage IIIB non-small cell lung carcinoma (NSCLC) invading the mediastinum (T4).
  • Three patients received a preoperative chemotherapy (n = 2) or radiochemotherapy (n = 1).
  • The procedure was extended to one of the following structures: superior vena cava (SVC) (n = 17), aorta (n = 1), left atrium (n = 5) and carina (n = 6).
  • Seventeen patients had a postoperative regimen including radiochemotherapy (n = 12), radiotherapy (n = 4), or chemotherapy (n = 1).
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adenocarcinoma / therapy. Adult. Aged. Carcinoma, Large Cell / pathology. Carcinoma, Large Cell / surgery. Carcinoma, Large Cell / therapy. Carcinoma, Neuroendocrine / pathology. Carcinoma, Neuroendocrine / surgery. Carcinoma, Neuroendocrine / therapy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Carcinoma, Squamous Cell / therapy. Cause of Death. Combined Modality Therapy. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Prognosis. Retrospective Studies. Survival Analysis

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  • (PMID = 11463554.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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25. Lucchi M, Viti A, Melfi F, Ambrogi M, Givigliano F, Dini P, Mussi A: IIIB-T4 non-small cell lung cancer: indications and results of surgical treatment. J Cardiovasc Surg (Torino); 2007 Jun;48(3):369-74
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  • [Title] IIIB-T4 non-small cell lung cancer: indications and results of surgical treatment.
  • We have reviewed our experience with T4 NSCLC patients who underwent surgery with the aim of debating the indications and results of surgical treatment in this highly selected group of patients.
  • The tumors were classified T4 for the following reasons: intralobar satellite metastasis in 24 cases, direct mediastinum invasion in 18 cases, malignant pleural effusion in 7 cases, involvement of the superior vena cava in 4 cases, marginal invasion of the vertebral body in 3 cases, involvement of the carena in 3 cases and invasion of the left atrium in 1 case.
  • Thirteen patients had undergone neo-adjuvant chemotherapy while 39 underwent adjuvant therapies.
  • The prognosis was neither affected by the subtype of T4 tumor nor by the use of adjuvant therapies and/or neoadjuvant chemotherapy but only by the N status.
  • [MeSH-minor] Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Lymph Nodes / pathology. Lymphatic Metastasis / diagnosis. Male. Mediastinoscopy. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Neoplasm Staging / methods. Radiotherapy, Adjuvant. Risk Assessment. Risk Factors. Thoracic Surgery, Video-Assisted. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17505443.001).
  • [ISSN] 0021-9509
  • [Journal-full-title] The Journal of cardiovascular surgery
  • [ISO-abbreviation] J Cardiovasc Surg (Torino)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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26. Uemura S, Maeda H, Munekage M, Yoshioka R, Okabayashi T, Hanazaki K: Hepatic resection for metastatic colon cancer in patients with situs inversus totalis complicated by multiple anomalies of the hepatobiliary system: the first case report. J Gastrointest Surg; 2009 Sep;13(9):1724-7
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  • Despite postoperative adjuvant chemotherapy, tumor markers increased and multiple liver metastases were detected on abdominal ultrasonography.
  • Enhanced computed tomography revealed not only liver metastases but also hepatobiliary anomalies associated with situs inversus totalis as follows:.
  • (1) portal vein located anterior to the common bile duct or hepatic artery, (2) proper hepatic artery arising from the superior mesenteric artery, (3) "left" (right in normal population)-sided umbilical portion of the portal vein and total ramification of intrahepatic portal branches from that point, (4) hepatic vein directly communicating to the "left" atrium.
  • For the treatment of hepatic metastases from sigmoid colon cancer in a patient with situs inversus totalis, "left" hepatic lobectomy, partial hepatectomy, and radiofrequency ablation therapy were performed.
  • Adjuvant chemotherapy has been continued for 2 years after the second operation and the patient is doing well without recurrence.
  • [MeSH-minor] Catheter Ablation / methods. Chemotherapy, Adjuvant. Colectomy / methods. Follow-Up Studies. Hepatectomy / methods. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Risk Assessment. Time Factors. Tomography, X-Ray Computed. Treatment Outcome. Ultrasonography, Doppler

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  • (PMID = 19415395.001).
  • [ISSN] 1873-4626
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Mehta RS, Schubbert T, Marshall J, Carpenter PM: Rational and successful use of carboplatin and albumin-bound paclitaxel in a patient with recurrent metaplastic carcinoma who presented with multi-organ tumor emboli. Clin Breast Cancer; 2009 Feb;9(1):56-9
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  • We demonstrate successful treatment of recurrent chondroid-metaplastic breast cancer.
  • A diagnosis of tumor embolism was suspected when a chest radiograph performed as part of a work-up for stroke demonstrated several lung nodules, with 1 lung nodule invading the pulmonary vein and extending into the left atrium-the source of tumor emboli.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Breast Neoplasms / drug therapy. Metaplasia / drug therapy. Neoplasm Recurrence, Local / drug therapy
  • [MeSH-minor] Albumin-Bound Paclitaxel. Albumins / administration & dosage. Carboplatin / administration & dosage. Female. Humans. Middle Aged. Paclitaxel / administration & dosage. Treatment Outcome

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  • (PMID = 19299243.001).
  • [ISSN] 1526-8209
  • [Journal-full-title] Clinical breast cancer
  • [ISO-abbreviation] Clin. Breast Cancer
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA062203
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Albumin-Bound Paclitaxel; 0 / Albumins; BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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