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Items 1 to 22 of about 22
1. Kinebuchi Y, Ogawa T, Kato H, Igawa Y, Nishizawa O, Miyagawa S: Testicular cancer with tumor thrombus extending to the inferior vena cava successfully removed using veno-venous bypass: a case report. Int J Urol; 2007 May;14(5):458-60
MedlinePlus Health Information. consumer health - Testicular Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Testicular cancer with tumor thrombus extending to the inferior vena cava successfully removed using veno-venous bypass: a case report.
  • A 33-year-old man with a left testicular tumor was referred to Shinshu University Hospital for advanced therapy.
  • Radiographic imaging revealed multiple metastases in the retroperitoneal lymph nodes (RPLN) and bilateral lungs, as well as tumor thrombus that extended from the left renal vein to the inferior vena cava (IVC) adjacent to the right atrium.
  • After orchidectomy, a diagnosis of embryonal carcinoma was made with a clinical stage of T1N2M1bS3, which has a poor prognosis, based on the International Germ Cell Cancer Collaborative Group consensus.
  • After eight courses of chemotherapy, the patient's tumor markers normalized and the lung metastases disappeared, but the RPLN and tumor thrombus remained.
  • [MeSH-minor] Adult. Anastomosis, Surgical / methods. Humans. Male. Neoplasm Invasiveness. Remission Induction. Renal Artery / surgery. Renal Veins / surgery. Vascular Surgical Procedures / methods

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  • (PMID = 17511736.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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2. Takeda K, Uehara M, Tei N, Shimizu K, Imazu T, Yoshimura K, Kiyohara H: [A case of retroperitoneal myxofibrosarcoma]. Hinyokika Kiyo; 2009 Nov;55(11):711-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 63-year-old man presented to our hospital suffering from dull pain in his right flank and general malaise.Abdominal computed tomography (CT) revealed a 21X14 cm retroperitoneal tumor adjacent to the right kidney.
  • Histopathological diagnosis was high-grade myxofibrosarcoma.
  • Eleven months after the original tumor excision, CT revealed lymph node metastasis dorsal to the inferior vena cava,which was also removed.
  • Because he refused to receive adjuvant chemotherapy,he was observed for 2 months until CT revealed multiple liver metastases and para-aortic lymph node metastasis.
  • He underwent 1 cycle of combined chemotherapy with doxorubicin and carboplatin,but metastatic lesions grew larger rapidly and his general state became too poor to continue chemotherapy.
  • [MeSH-minor] Humans. Male. Middle Aged. Neoplasm Metastasis

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  • (PMID = 19946191.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 15
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3. Mahmood A, Cleasby M, Hübscher SG, Khaira HS: Ewing's sarcoma of the inferior vena cava. Vasc Endovascular Surg; 2009 Aug-Sep;43(4):403-5
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  • [Title] Ewing's sarcoma of the inferior vena cava.
  • Ewing's sarcoma most commonly arises from bone but may also arise from soft tissues.
  • Sarcoma of the inferior vena cava is a rare entity that requires multimodal therapy including surgical resection and vascular reconstruction.
  • We describe the first reported case of Ewing's sarcoma of the inferior vena cava.
  • [MeSH-major] Sarcoma, Ewing / secondary. Vascular Neoplasms / diagnosis. Vena Cava, Inferior / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Immunohistochemistry. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Middle Aged. Neoplasm Invasiveness. Tomography, X-Ray Computed. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 19351649.001).
  • [ISSN] 1538-5744
  • [Journal-full-title] Vascular and endovascular surgery
  • [ISO-abbreviation] Vasc Endovascular Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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4. Zhang H, Kong Y, Zhang H, He X, Zhang HY, Liu C, Xiao M, Xu X: Leiomyosarcoma of the inferior vena cava: case report and treatment of recurrence with repeat surgery. Ann Vasc Surg; 2010 Apr;24(3):417.e5-9
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  • [Title] Leiomyosarcoma of the inferior vena cava: case report and treatment of recurrence with repeat surgery.
  • Leiomyosarcoma of the inferior vena cava (IVC) is an extremely rare malignancy with poor prognosis due to late diagnosis.
  • Surgical resection currently remains the best treatment; however, recurrence frequently occurs and the 5-year survival rate is only 31%.
  • The aim of this study is to report a case of IVC leiomyosarcoma and treatment of recurrence with repeat surgery.
  • A 36-year-old woman with a high-grade leiomyosarcoma originating from the infrahepatic IVC underwent an en bloc excision of the tumor.
  • Since the patient showed no response to adjuvant chemotherapy (i.e., a combination of 5-fluorouracil and gemcitabine), repeat operations were used as the main treatment modality for recurrence.
  • The median time to recurrence was 15 months (range 8-27).
  • The middle and upper IVC segments were involved in the local recurrence, and metastatic lesions occurred in multiple sites including the stomach, omentum, mesentery, left liver, and pelvic cavity.
  • Neither complication related to the venous blood flow in the IVC nor renal impairment was noted.
  • Our results suggest that in the setting of chemotherapy-refractory IVC leiomyosarcoma repeat surgery may be an alternative treatment for recurrence and improve survival time.
  • [MeSH-major] Abdominal Neoplasms / surgery. Digestive System Surgical Procedures. Leiomyosarcoma / surgery. Neoplasm Recurrence, Local. Pelvic Neoplasms / surgery. Vascular Neoplasms / surgery. Vascular Surgical Procedures. Vena Cava, Inferior / surgery
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Chemotherapy, Adjuvant. Drug Resistance, Neoplasm. Female. Humans. Reoperation. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • [Copyright] Copyright (c) 2010 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20036495.001).
  • [ISSN] 1615-5947
  • [Journal-full-title] Annals of vascular surgery
  • [ISO-abbreviation] Ann Vasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Yamamoto Y, Goto M, Okamoto T, Tomita I, Murayama A, Sawa M, Noguchi Y, Hoshikawa Y, Shimizu A: [Chemotherapy-naïve advanced malignant fibrohistiocytoma presenting IVC syndrome case report]. Gan To Kagaku Ryoho; 2010 Feb;37(2):355-7
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  • [Title] [Chemotherapy-naïve advanced malignant fibrohistiocytoma presenting IVC syndrome case report].
  • Computed tomography (CT) and 3 dimensional CT showed an 8-cm tumor on the IVC, partially replacing iliac vessels and invading the psoas muscle.
  • A diagnosis of malignant fibrohistiocytoma was made by pathological examination of biopsied specimens at exploratory laparotomy.
  • Five courses of combination chemotherapy of ifosfamide (IFM) and doxorubicin (DXR) resulted in PR.
  • Another 5 courses of chemotherapy with epirubicin and IFM were added.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Doxorubicin / therapeutic use. Histiocytoma, Malignant Fibrous / complications. Histiocytoma, Malignant Fibrous / drug therapy. Ifosfamide / therapeutic use. Superior Vena Cava Syndrome / etiology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Aged. Biopsy. Humans. Male. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 20154502.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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6. Giannoulia-Karadana A, Moschovi M, Koutsovitis P, Tolis G, Tzortzatou-Stathopoulou F: Inferior vena cava and right atrial thrombosis in children with nephroblastoma: diagnostic and therapeutic problems. J Pediatr Surg; 2000 Oct;35(10):1459-61
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  • [Title] Inferior vena cava and right atrial thrombosis in children with nephroblastoma: diagnostic and therapeutic problems.
  • BACKGROUND: The neoplastic thrombus in Wilms' tumor rarely can extend in to the inferior vena cava or to the right atrium.
  • The neoplastic thrombus usually is diagnosed concurrently with the tumor, although in some cases the diagnosis of the thrombus may precede the diagnosis of nephroblastoma.
  • METHODS: Among 90 children with Wilms' tumor who were treated in the authors' unit, 4 had extensive tumor thrombosis of the inferior vena cava or the right atrium.
  • One of these patients was found with a life-threatening thrombosis of the inferior vena cava and the right atrium, which was treated surgically; in this case, the diagnosis of nephroblastoma was made postoperatively.
  • As for the 3 remaining patients the diagnosis of neoplastic thrombosis and Wilms' tumor was made simultaneously.
  • In the other 3 cases the thrombus resolved with chemotherapy only.
  • Chemotherapy is suggested in cases lacking clinical symptoms of thrombosis.
  • [MeSH-major] Heart Atria. Heart Diseases / diagnosis. Heart Diseases / etiology. Kidney Neoplasms / complications. Thrombosis / diagnosis. Thrombosis / etiology. Vena Cava, Inferior. Wilms Tumor / complications
  • [MeSH-minor] Child. Child, Preschool. Female. Humans. Magnetic Resonance Imaging. Neoplasm Invasiveness. Tomography, X-Ray Computed


7. Suzuki S, Yasuhara K, Koyano T, Obayashi T: [Tumor thrombectomy for endometrial stromal sarcoma extending into the inferior vena cava and the right atrium from the uterus]. Kyobu Geka; 2008 Feb;61(2):139-42
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  • [Title] [Tumor thrombectomy for endometrial stromal sarcoma extending into the inferior vena cava and the right atrium from the uterus].
  • We report an extremely rare case of endometrial stromal sarcoma (ESS) extending into the inferior vena cava and the right atrium.
  • The chest-abdominal computed tomography (CT) showed tumor thrombus invading the inferior vena cava and right atrium with multiple lung metastasis.
  • The pathological diagnosis of the tumor thrombus was low-grade ESS originating from the uterus.
  • After thrombectomy, she underwent chemotherapy with carboplatin and paclitaxel.
  • Surgical resection and chemotherapy to low-grade ESS achieved favourable prognosis.
  • [MeSH-major] Endometrial Neoplasms / pathology. Heart Neoplasms / surgery. Neoplastic Cells, Circulating. Sarcoma, Endometrial Stromal / surgery. Vascular Neoplasms / surgery. Vena Cava, Inferior
  • [MeSH-minor] Aged. Cardiopulmonary Bypass. Chemotherapy, Adjuvant. Circulatory Arrest, Deep Hypothermia Induced. Female. Heart Atria. Humans. Lung Neoplasms / secondary. Neoplasm Invasiveness. Treatment Outcome

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  • (PMID = 18268952.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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8. Hilliard NJ, Heslin MJ, Castro CY: Leiomyosarcoma of the inferior vena cava: three case reports and review of the literature. Ann Diagn Pathol; 2005 Oct;9(5):259-66
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  • [Title] Leiomyosarcoma of the inferior vena cava: three case reports and review of the literature.
  • We describe 3 cases of leiomyosarcoma of the inferior vena cava (IVC) and review the literature describing clinicopathologic features of 211 cases and the outcome.
  • The most common symptoms were abdominal pain or mass (57%), Budd-Chiari syndrome (17%), and deep vein thrombosis (4%).
  • The most frequent site of tumor origin is the middle segment of the IVC (33%).
  • Of all patients, 47% underwent complete resection, 24% had complete resection with preoperative or postoperative chemotherapy and/or radiation, and 5% had palliative surgery.
  • Tumors involving level 2 of the IVC have the best prognosis and tumors of level 1 have the worse prognosis.
  • [MeSH-major] Leiomyosarcoma / pathology. Leiomyosarcoma / physiopathology. Vascular Neoplasms / pathology. Vascular Neoplasms / physiopathology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Aged. Carcinoma, Renal Cell / pathology. Diagnosis, Differential. Female. Hemangiosarcoma / pathology. Humans. Middle Aged. Neoplasm Metastasis / pathology. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / surgery. Sarcoma / pathology. Treatment Outcome

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  • (PMID = 16198953.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Badawi JK, Kittner T, Manseck A, Wirth MW: Intraluminal tumour thrombus of a mixed non-seminomatous germ cell tumour of testis within the inferior vena cava. Onkologie; 2005 Feb;28(2):98-100
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  • [Title] Intraluminal tumour thrombus of a mixed non-seminomatous germ cell tumour of testis within the inferior vena cava.
  • BACKGROUND: Intracaval tumour thrombus developed per continuitatem from a primary testicular tumour is rare.
  • CASE REPORT: A patient with metastatic mixed non-seminomatous germ cell tumour of the testis extending into the inferior vena cava (IVC) is presented.
  • Computed tomography revealed the tumour thrombus as filling defect in the IVC extending nearly to the right renal vein.
  • Duplex sonography detected a partial thrombosis of the IVC.
  • Combination chemotherapy led to regression of pulmonal metastases and the intraluminal tumour thrombus.
  • The thrombus originated from the ostium of the right testicularis vein in the IVC.
  • Histological examination revealed no vital tumour tissue.
  • CONCLUSION: In patients with testicular cancer information about pathological processes of the IVC is important for therapeutic management.
  • Testicular tumours seldom extend up the IVC.
  • [MeSH-major] Neoplasms, Germ Cell and Embryonal / diagnosis. Neoplasms, Germ Cell and Embryonal / therapy. Testicular Neoplasms / diagnosis. Testicular Neoplasms / therapy. Vascular Neoplasms / diagnosis. Vascular Neoplasms / therapy
  • [MeSH-minor] Adult. Humans. Lung Neoplasms / complications. Lung Neoplasms / diagnosis. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Neoplasm Invasiveness. Treatment Outcome. Vena Cava, Inferior / pathology. Vena Cava, Inferior / radiography. Vena Cava, Inferior / surgery

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  • (PMID = 15665558.001).
  • [ISSN] 0378-584X
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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10. Al-Rikabi A, Hussain AA, Buchler M, Al-Muzrakchi A, Jyothi CR: Primary leiomyosarcoma of the inferior vena cava: report of a case diagnosed by fine needle aspiration cytology and confirmed by histopathologic examination. Acta Cytol; 2007 May-Jun;51(3):477-9
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  • [Title] Primary leiomyosarcoma of the inferior vena cava: report of a case diagnosed by fine needle aspiration cytology and confirmed by histopathologic examination.
  • BACKGROUND: Leiomyosarcoma is a malignant neoplasm and can originate within major abdominal veins, including the inferior venacava (IVC).
  • CASE: A 45-year-old woman presented with upper abdominal pain and a mass lesion in the liver and within the lumen of the IVC.
  • A diagnosis of primary leiomyosarcoma of the IVC was made by using imaging techniques,fine needle aspiration cytology and histopathologic examination of the resected specimen.
  • CONCLUSION: In patients presenting with vague upper abdominal pain and radiologic features of a hepatic mass extending to major veins, the rare possibility of primary leiomyosarcoma of the IVC shoald he considered and investigated by both fine needle aspiration cytology and intraoperative histology.
  • Early surgical intervention and/or postoperative chemotherapy and radiotherapy are associated with improved survival.
  • [MeSH-major] Leiomyosarcoma / pathology. Vascular Neoplasms / pathology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Female. Humans. Middle Aged. Preoperative Care. Tomography, X-Ray Computed

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  • (PMID = 17536560.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Kourda N, El Atat R, Derouiche A, Zeddini A, Chebil M, Baltagi S, Zermani R: Primitive neuroectodermal tumor of the kidney with vena caval tumor thrombus: diagnosis and management. Pathologica; 2007 Apr;99(2):57-60
MedlinePlus Health Information. consumer health - Kidney Cancer.

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  • [Title] Primitive neuroectodermal tumor of the kidney with vena caval tumor thrombus: diagnosis and management.
  • We report a case of 28-year-old male with PNET of the kidney with inferior vena caval thrombus.
  • He underwent two further cycles of high dose chemotherapy and died 9 months after diagnosis due to liver metastases.
  • The diagnosis of renal PNET must be considered in young patients with renal neoplasm, particularly those with advanced disease at presentation.
  • Achieving exact diagnosis has important clinical consequences.
  • [MeSH-major] Kidney Neoplasms / pathology. Kidney Neoplasms / therapy. Neoplastic Cells, Circulating / pathology. Neuroectodermal Tumors, Primitive / pathology. Neuroectodermal Tumors, Primitive / therapy. Vena Cava, Inferior

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  • (PMID = 17633810.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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12. Hamy A, d'Alincourt A, Floch I, Madoz A, Paineau J, Lerat F: [Bisegmentectomy 7-8: importance of preoperative diagnosis of a right inferior hepatic vein]. Ann Chir; 2004 Jun;129(5):282-5
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  • [Title] [Bisegmentectomy 7-8: importance of preoperative diagnosis of a right inferior hepatic vein].
  • A need to transect the right hepatic vein at its entry into the vena cava indicates a need to remove the entire right posterior segment.
  • The circumstances which allow such preservation are the presence of a stout inferior right hepatic vein and the ability to recognize the presence of the vein in the preoperative staging.
  • In patients with possible impaired hepatic function (cirrhosis, chemotherapy), preservation of hepatic parenchyma is an important consideration during resection for hepatic tumors.
  • [MeSH-minor] Adult. Aged. Breast Neoplasms / pathology. Colonic Neoplasms / pathology. Female. Humans. Length of Stay / statistics & numerical data. Liver Function Tests. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging / methods. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15220102.001).
  • [ISSN] 0003-3944
  • [Journal-full-title] Annales de chirurgie
  • [ISO-abbreviation] Ann Chir
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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13. Cecchetto G, Alaggio R, Scarzello G, Dall'Igna P, Martino A, Bisogno G, Guglielmi M: Teratoid Wilms' tumor: report of a unilateral case. J Pediatr Surg; 2003 Feb;38(2):259-61
MedlinePlus Health Information. consumer health - Wilms Tumor.

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  • Teratoid Wilms' tumor is a rare histologic variant of the classical Wilms' tumor, containing predominantly heterologous tissues (adipose, glial, muscle, cartilage, or bone).
  • The mass, which originated from the right kidney, was very large and encased the inferior vena cava and renal vessels.
  • Despite the enormous dimensions of the tumor and the involvement of the inferior vena cava, a radical excision was obtained, and now the child is well 32 months after surgery.
  • Surgery should be the treatment of choice, because the efficacy of chemotherapy and radiotherapy is probably reduced by the high amount of differentiated and mature tissue which characterizes this neoplasm.
  • [MeSH-minor] Chemotherapy, Adjuvant. Child, Preschool. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Radiotherapy, Adjuvant. Teratoma / diagnosis. Teratoma / pathology. Treatment Outcome. Vena Cava, Inferior / pathology

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  • [Copyright] Copyright 2003, Elsevier Science (USA). All rights reserved.
  • (PMID = 12596119.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Stefka J, Cleveland JC, Lucia MS, Singh M: Sarcomatoid intracardiac metastasis of a testicular germ cell tumor closely resembling primary cardiac sarcoma. Hum Pathol; 2003 Oct;34(10):1074-7
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  • This report describes a 40-year-old man with a remote history of testicular mixed nonseminomatous germ cell tumor (NSGCT) treated by surgery and chemotherapy.
  • He presented 10 years later with shortness of breath and was found to have a mass occupying the right atrium, based high in the superior vena cava.
  • The sarcomatous and myxomatous histological appearance of the neoplasm closely resembled a primary cardiac sarcoma.
  • However, immunohistochemical studies confirmed the diagnosis of metatstatic sarcomatoid germ cell tumor.
  • These neoplasms are thought to arise from the spindle cell component of the yolk sac tumor that is resistant to chemotherapy.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Diagnosis, Differential. Echocardiography. Heart Atria / pathology. Humans. Immunohistochemistry. Male. Vena Cava, Inferior / pathology

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  • (PMID = 14608547.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Szavay P, Luithle T, Semler O, Graf N, Fuchs J: Surgery of cavoatrial tumor thrombus in nephroblastoma: a report of the SIOP/GPOH study. Pediatr Blood Cancer; 2004 Jul;43(1):40-5
MedlinePlus Health Information. consumer health - Wilms Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Resection of a Wilms tumor extending through the inferior vena cava into the right atrium represents a challenge to the pediatric surgeon.
  • Exact preoperative diagnosis is essential to identify the tumor and its intravascular extension.
  • The feasibility of a complete resection is important as it guides subsequent therapy such as chemotherapy and radiation.
  • PROCEDURE: In order to define these issues, we reviewed the records of 33 of 1,151.
  • Patients enrolled in the SIOP 93-01/GPOH Study and the SIOP 2001/GPOH Study who had a tumor thrombus into the inferior vena cava and into the right atrium.
  • RESULTS: The median age at diagnosis was 3.73 years.
  • Twenty-four patients had a tumor thrombus into the inferior vena cava, in nine patients the thrombus reached into the right atrium.
  • CONCLUSION: Our report suggests that Wilms tumor extending to the inferior vena cava and the right atrium is technical challenging, but with adequate preoperative diagnosis and a multidisciplinary surgical approach including cardiopulmonary bypass and hypothermia, the prognosis is favorable.
  • [MeSH-major] Cardiopulmonary Bypass. Heart Atria. Kidney Neoplasms / surgery. Thrombosis / surgery. Vena Cava, Inferior. Wilms Tumor / surgery
  • [MeSH-minor] Child. Child, Preschool. Combined Modality Therapy. Female. Germany / epidemiology. Humans. Hypothermia, Induced. Infant. Intraoperative Complications / epidemiology. Male. Neoplasm Invasiveness. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Survival Rate

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  • [Copyright] Copyright 2004 Wiley-Liss, Inc.
  • (PMID = 15170888.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Hall G, Grant R, Weitzman S, Maze R, Greenberg M, Gerstle JT: Predictors of surgical outcome in Wilms' tumor: a single-institution comparative experience. J Pediatr Surg; 2006 May;41(5):966-71
MedlinePlus Health Information. consumer health - Wilms Tumor.

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  • BACKGROUND: The merits of primary nephrectomy (PN) vs preoperative chemotherapy (PC) for patients with Wilms' tumor (WT) are much debated.
  • Tumor inhomogeneity, tumor size, and inferior vena cava compression/clot at diagnosis did not affect incidence of spill.
  • Preoperative chemotherapy and PN had equal rates of surgical complications.
  • Preoperative chemotherapy resulted in 12 (10.5%) of 114 local recurrences vs 5 (10.8%) of 46 with PN.
  • CONCLUSIONS: Preoperative chemotherapy and PN are equally effective in the treatment of WT with no difference in tumor spillage.
  • [MeSH-major] Kidney Neoplasms / drug therapy. Kidney Neoplasms / surgery. Wilms Tumor / drug therapy. Wilms Tumor / surgery
  • [MeSH-minor] Child, Preschool. Humans. Neoplasm Seeding. Treatment Outcome

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  • (PMID = 16677894.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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17. Gosev I, Sirić F, Gasparović H, Ugljen R, Nola M, Jelić I: Surgical treatment of a primary cardiac lymphoma presenting with tamponade physiology. J Card Surg; 2006 Jul-Aug;21(4):414-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of a primary cardiac lymphoma presenting with tamponade physiology.
  • Echocardiographic evidence of impending cardiac tamponade and obstruction of the inferior vena cava (IVC) with the tumor was seen.
  • Pathohistological diagnosis showed diffuse large B-cell lymphoma of centroblastic subtype.
  • Chemotherapy remains the standard treatment of PCL, with surgery reserved for relieving life-threatening complications of the neoplasm.
  • [MeSH-major] Cardiac Surgical Procedures. Cardiac Tamponade / physiopathology. Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Lymphoma, B-Cell / diagnosis. Lymphoma, B-Cell / surgery. Lymphoma, Large B-Cell, Diffuse / diagnosis. Lymphoma, Large B-Cell, Diffuse / surgery
  • [MeSH-minor] Aged. Cardiopulmonary Bypass. Diagnosis, Differential. Echocardiography. Heart Atria / pathology. Heart Atria / ultrasonography. Humans. Immunocompromised Host. Magnetic Resonance Imaging. Male

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  • (PMID = 16846425.001).
  • [ISSN] 0886-0440
  • [Journal-full-title] Journal of cardiac surgery
  • [ISO-abbreviation] J Card Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Schenk JP, Graf N, Günther P, Ley S, Göppl M, Kulozik A, Rohrschneider WK, Tröger J: Role of MRI in the management of patients with nephroblastoma. Eur Radiol; 2008 Apr;18(4):683-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Radiological findings play an important role in therapy study trials of SIOP (International Society of Pediatric Oncology), especially for indicating preoperative chemotherapy.
  • In the past few years MRI has gained great importance in imaging of nephroblastoma and has replaced computed tomography (CT).
  • The aim of this review is to present the diagnostic possibilities of MRI in relation to the requirements of therapy studies.
  • A special focus of MRI in distant staging is venous extent of the tumor into the inferior vena cava.
  • In addition, MRI has an important role in monitoring chemotherapy and in preoperative planning by volume rendering and three-dimensional postprocessing.
  • [MeSH-major] Kidney Neoplasms / diagnosis. Magnetic Resonance Imaging / methods. Wilms Tumor / diagnosis
  • [MeSH-minor] Child. Contrast Media. Humans. Image Interpretation, Computer-Assisted. Imaging, Three-Dimensional. Neoplasm Staging

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  • (PMID = 18193429.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 30
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19. Kanai T, Takabayashi T, Kawano Y, Kuramochi S, Miyazawa N: A case of postoperative recurrence of fibrolamellar hepatocellular carcinoma with increased vitamin B12 binding capacity in a young Japanese female. Jpn J Clin Oncol; 2004 Jun;34(6):346-51
MedlinePlus Health Information. consumer health - Liver Cancer.

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  • A 17-year-old Japanese female underwent major hepatic resection for a huge fibrolamellar hepatocellular carcinoma that was compressing the inferior vena cava.
  • Several types of chemotherapy, including intraperitoneal injection of epirubicin, were applied and improved the patient's quality of life somewhat, but the patient died of recurrent disease 34 months after the initial hepatic resection.
  • An aggressive strategy should be chosen, which consists mainly of precise surgical resection and postoperative multimodality therapy, including chemotherapy.
  • [MeSH-major] Carcinoma, Hepatocellular / diagnosis. Liver Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Hepatectomy. Humans. Lymphatic Metastasis. Neoplasm Recurrence, Local. Postoperative Period. Tomography, X-Ray Computed. Transcobalamins / analysis

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  • (PMID = 15333688.001).
  • [ISSN] 0368-2811
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Transcobalamins
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20. Schettini ST, da Fonseca JH, Abib SC, Telles CA, Haber MX, Rizzo MF, Saba da Silva NS, Petrilli AS: Management of Wilms' tumor with intracardiac extension. Pediatr Surg Int; 2000;16(7):529-32
MedlinePlus Health Information. consumer health - Wilms Tumor.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We review our experience and the literature in treating 4 patients with Wilms' tumor (WT) with intracardiac extension among 92 patients with this neoplasm.
  • We had no surgical complications and conclude that the preoperative diagnosis is extremely important.
  • We propose that preoperative chemotherapy should be used, as it shrinks the thrombus and causes desirable adherence of the thrombus to the venous wall, reducing the probability of thromboembolism during the surgical procedure.
  • [MeSH-minor] Adolescent. Cardiopulmonary Bypass. Child. Child, Preschool. Female. Heart Arrest, Induced. Heart Atria / pathology. Heart Atria / surgery. Humans. Hypothermia, Induced. Male. Neoadjuvant Therapy. Treatment Outcome. Vena Cava, Inferior / pathology. Vena Cava, Inferior / surgery

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  • (PMID = 11057562.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] GERMANY
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21. Langer P, Bartsch D, Moebius E, Rothmund M, Nies C: Adrenocortical carcinoma--our experience with 11 cases. Langenbecks Arch Surg; 2000 Oct;385(6):393-7
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  • Diagnosis is mostly delayed and prognosis is poor.
  • PATIENTS/METHODS: The data of the patients with ACC were reviewed and presenting symptoms, diagnostic procedures, treatment and results of follow-up were evaluated.
  • At the time of diagnosis, five tumours were classified as stage II, two as stage III and four as stage IV.
  • Five patients received additional chemotherapy.
  • Five of the 11 patients are still alive (three stage II, one stage III and one stage IV at the time of diagnosis), three of whom have no evidence of disease (14, 48 and 71 months after surgery).
  • CONCLUSIONS: Venography should be performed prior to surgery to detect or exclude thrombotic tumour masses in the suprarenal vein, renal vein or inferior vena cava.
  • There is no consensus concerning adjuvant therapy.

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  • (PMID = 11127523.001).
  • [ISSN] 1435-2443
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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22. Shimizu J, Arano Y, Murata T, Ishikawa N, Yachi T, Nomura T, Minato H: A case of intrathoracic giant malignant peripheral nerve sheath tumor in neurofibromatosis type I (von Recklinghausen's disease). Ann Thorac Cardiovasc Surg; 2008 Feb;14(1):42-7
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  • [Title] A case of intrathoracic giant malignant peripheral nerve sheath tumor in neurofibromatosis type I (von Recklinghausen's disease).
  • She underwent surgery to alleviate respiratory and circulatory disorders caused by compression of the right lung and inferior vena cava due to the giant tumor.
  • Neither an optimal extent of resection needed for complete resection of this tumor nor an optimal regimen of chemotherapy, radiotherapy, or other therapy for the tumor has yet been established.
  • [MeSH-minor] Adult. Diagnosis, Differential. Fatal Outcome. Humans. Magnetic Resonance Imaging. Neoplasm Recurrence, Local. Tomography, X-Ray Computed

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  • (PMID = 18292741.001).
  • [ISSN] 1341-1098
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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