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Items 1 to 22 of about 22
1. Ihtiyar E, Paşaoğlu O, Erkasap S, Karakaş BR, Yaşar FN: Perforated mixed carcinoid-adenocarcinoma in transverse colon and at gastroenterostomy site: case report. World J Surg Oncol; 2010;8:110
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perforated mixed carcinoid-adenocarcinoma in transverse colon and at gastroenterostomy site: case report.
  • Goblet cell carcinoid of the large intestine is a rare neoplasm, usually located in ascending colon and rectum.
  • A 60-year-old male patient underwent surgery after the diagnosis of acute abdomen.
  • Exploratory laparotomy revealed perforation with a diameter of 1 cm at the site of the previously performed gastroenterostomy and dilatation of the right colic flexure, secondary to a solid obstructive mass located in the mid-portion of transverse colon.
  • Histopathological investigation of the biopsies, taken from the gastroenterostomy site and the tumor, revealed mixed carcinoid-adenocarcinoma with carcinoid component, predominantly composed of goblet cells.
  • Our aim with this paper is to point out that more cases should be reported for more effective diagnosis, histopathological study, clinical investigation, treatment and prognosis of this specific neoplasm.
  • [MeSH-major] Carcinoid Tumor / pathology. Colonic Neoplasms / pathology. Gastroenterostomy. Intestinal Perforation / pathology
  • [MeSH-minor] Adenocarcinoma / drug therapy. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colon, Transverse / pathology. Combined Modality Therapy. Fluorouracil / therapeutic use. Humans. Laparotomy. Leucovorin / therapeutic use. Male. Middle Aged. Organoplatinum Compounds / therapeutic use. Prognosis

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  • [Cites] Pathol Int. 2003 Jul;53(7):457-62 [12828611.001]
  • [Cites] Am J Surg Pathol. 1988 Aug;12(8):607-11 [3400791.001]
  • [Cites] Cancer. 1974 Aug;34(2):338-44 [4852178.001]
  • (PMID = 21176192.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Adenocarcinoid tumor; Folfox protocol
  • [Other-IDs] NLM/ PMC3014938
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2. Tokumitsu S, Nozaki A, Kanazawa T, Tsunashima T: [A case of advanced pancreatic cancer treated successfully with self-expandable stent, PTEG and chemotherapy]. Gan To Kagaku Ryoho; 2007 Nov;34(12):2002-4
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  • [Title] [A case of advanced pancreatic cancer treated successfully with self-expandable stent, PTEG and chemotherapy].
  • He was complicated with multiple alimentary tract stenosis (duodenal third portion, ascending portion and splenic-flexure portion of colon) due to intraabdominal spread of malignancies.
  • The self-expandable metal stent was successfully placed in each stenotic portion with being effectively decompressed of his intestinal obstruction by the procedure of percutaneous transesophageal gastro-tubing (PTEG).
  • These treatments improved his symptoms to ingest orally in addition to the tube feeding per PTEG.
  • Furthermore, he has been receiving adjuvant chemotherapy with GEM, S-1, and CPT-11 for 9 months at outpatient department.
  • We concluded a combined procedure of self-expandable stent and PTEG was useful palliative treatment in malignant gastrointestinal obstruction of advanced pancreatic cancer.
  • [MeSH-major] Pancreatic Neoplasms / drug therapy. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Humans. Male. Middle Aged. Neoplasm Staging. Stents. Time Factors. Tomography, X-Ray Computed

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  • (PMID = 18219879.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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3. Martenson JA Jr, Willett CG, Sargent DJ, Mailliard JA, Donohue JH, Gunderson LL, Thomas CR Jr, Fisher B, Benson AB 3rd, Myerson R, Goldberg RM: Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130. J Clin Oncol; 2004 Aug 15;22(16):3277-83
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  • [Title] Phase III study of adjuvant chemotherapy and radiation therapy compared with chemotherapy alone in the surgical adjuvant treatment of colon cancer: results of intergroup protocol 0130.
  • PURPOSE: Some patients with colon cancer have a high risk of local recurrence postoperatively.
  • This trial was undertaken to determine whether radiation therapy added to an adjuvant chemotherapy regimen improves outcome in high-risk patients.
  • PATIENTS AND METHODS: Patients with resected colon cancer with tumor adherence or invasion of surrounding structures, or with T3N1 or T3N2 tumors of the ascending or descending colon were randomly assigned to receive fluorouracil and levamisole therapy with or without radiation therapy.
  • Patients who received chemotherapy and radiation therapy (chemoRT) received 45 to 50.4 Gy in 25 to 28 fractions beginning 28 days after starting chemotherapy.
  • RESULTS: Overall 5-year survival was 62% for chemotherapy patients and 58% for chemoRT patients (P >.50); 5-year disease-free survival was 51% for both groups (P >.50).
  • Toxicity (>/= grade 3) occurred in 42% of chemotherapy patients and 54% of chemoRT patients (P =.04).
  • Leukopenia (>/= grade 3) occurred in 10% of chemotherapy patients and 22% of chemoRT patients (P =.02).
  • No significant difference in nonhematologic toxicity (>/= grade 3) was observed between chemoRT and chemotherapy patients (35% v 44%; P =.26).
  • CONCLUSION: Patients who received chemotherapy or chemoRT had similar overall survival and disease-free survival.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colonic Neoplasms / drug therapy. Colonic Neoplasms / radiotherapy. Neoplasm Recurrence, Local / prevention & control
  • [MeSH-minor] Administration, Oral. Adult. Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Combined Modality Therapy. Disease-Free Survival. Female. Fluorouracil / administration & dosage. Humans. Infusions, Intravenous. Levamisole / administration & dosage. Male. Middle Aged. Radiotherapy, Adjuvant. Risk Factors. Treatment Outcome

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  • [CommentIn] J Clin Oncol. 2004 Aug 15;22(16):3215-7 [15249588.001]
  • (PMID = 15249584.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 15083; United States / NCI NIH HHS / CA / CA 21115; United States / NCI NIH HHS / CA / CA 21661; United States / NCI NIH HHS / CA / CA 22433; United States / NCI NIH HHS / CA / CA 25224; United States / NCI NIH HHS / CA / CA 31946; United States / NCI NIH HHS / CA / CA 32102; United States / NCI NIH HHS / CA / CA 32115; United States / NCI NIH HHS / CA / CA 37404; United States / NCI NIH HHS / CA / CA 37422; United States / NCI NIH HHS / CA / CA 63849; United States / NCI NIH HHS / CA / CA 774400
  • [Publication-type] Clinical Trial; Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 2880D3468G / Levamisole; U3P01618RT / Fluorouracil
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4. Yamaoka K, Inatsugi N, Yoshikawa S, Masuda T, Uchida H, Kuge H, Yokotani T, Yamaguchi T, Kawaguchi C, Shimobayashi T, Inagaki M, Matsuoka M, Tatsumi K, Saraya T, Otsuji T, Yamochi Y, Yamanishi K, Enomoto Y, Nonomura A, Sho M, Nakajima Y: [A surgical (pancreatoduodenectomy) case of lymph node metastatic recurrence of colon cancer after chemotherapy]. Gan To Kagaku Ryoho; 2010 Nov;37(12):2346-8
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  • [Title] [A surgical (pancreatoduodenectomy) case of lymph node metastatic recurrence of colon cancer after chemotherapy].
  • A woman in her fifties underwent a right hemicolectomy (D3) for cancer of the ascending colon in October 2007, definitively and pathologically diagnosed as papillary adenocarcinoma invading to the subserosa, and no metastasis was detected to lymph node.
  • After the chemotherapy (6 courses), we decided to perform a radical resection.
  • [MeSH-major] Adenocarcinoma, Papillary / pathology. Adenocarcinoma, Papillary / therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colonic Neoplasms / pathology. Colonic Neoplasms / therapy. Lymphatic Metastasis / pathology. Pancreatic Neoplasms / secondary. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Duodenum / surgery. Female. Fluorouracil / therapeutic use. Humans. Leucovorin / therapeutic use. Middle Aged. Neoplasm Recurrence, Local. Organoplatinum Compounds / therapeutic use. Pancreatectomy

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  • (PMID = 21224568.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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5. Seki H, Kurihara E, Iwata K, Saito J: [A case of local recurrence of colon cancer responding to chemotherapy with low-dose oxaliplatin, 5-FU and l-LV]. Gan To Kagaku Ryoho; 2007 Aug;34(8):1291-3
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  • [Title] [A case of local recurrence of colon cancer responding to chemotherapy with low-dose oxaliplatin, 5-FU and l-LV].
  • A 68-year-old woman underwent right colectomy for cancer of the ascending colon, followed by a local recurrence 26 months after surgery.
  • She presented with fever and right lower abdominal pain, and was admitted to the hospital for locally recurrent colorectal cancer and tumor rupture.
  • Our case suggests that the mFOLFOX 4 regimen is effective for advanced or recurrent colorectal cancer with less toxicities including neuropathy,thus enabling patients to undergo long-term therapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / blood. Colonic Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy
  • [MeSH-minor] Aged. Carcinoembryonic Antigen / blood. Colectomy. Combined Modality Therapy. Dose-Response Relationship, Drug. Drug Administration Schedule. Female. Fluorouracil / administration & dosage. Humans. Leucovorin / administration & dosage. Organoplatinum Compounds / administration & dosage

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  • (PMID = 17687216.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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6. Sato H, Kuroda M, Maruta M, Maeda K, Koide Y: Mucoepidermoid carcinoma of the ascending colon: report of a case. Surg Today; 2002;32(11):1004-7
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  • [Title] Mucoepidermoid carcinoma of the ascending colon: report of a case.
  • An ulcerating tumor was thus identified in the ascending colon.
  • The tumor consisted of PAS-positive mucin-producing cells, epidermoid cells, and intermediate cells.
  • No differentiated squamous cell carcinoma cells were identified in any part of the tumor.
  • The tumor was diagnosed as a mucoepidermoid carcinoma of the ascending colon.
  • Unfortunately, despite chemotherapy, the patient developed liver metastases and died of liver failure 10 months postoperatively.
  • [MeSH-minor] Aged. Colectomy. Fatal Outcome. Humans. Male. Neoplasm Invasiveness

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  • (PMID = 12444441.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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7. Matsuda T, Shikata S: [A long survival case of advanced colon cancer with lung metastasis and cancerous pleuritis responding to CPT-11 and S-1 combination therapy]. Gan To Kagaku Ryoho; 2008 Mar;35(3):511-3
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  • [Title] [A long survival case of advanced colon cancer with lung metastasis and cancerous pleuritis responding to CPT-11 and S-1 combination therapy].
  • A 71-year-old man underwent right hemicolectomy for an ascending colon cancer (stage II, Cur A) in September 2001.
  • Adjuvant chemotherapy with tegafur/uracil was performed, but CT scans and FDG-PET, conducted in May 2003, revealed cancerous pleuritis and lung metastasis.
  • Although 2 courses of the chemotherapy with LV+5-FU (RPMI regimen) were completed, progressive disease was confirmed.
  • Therefore, the chemotherapy with CPT-11 (100 mg/ day; day 1, 15)+S-1 (100 mg/day; day 1-21) was started in May 2004.
  • Only grade 2 vomiting was noted as an adverse reaction to the treatment, however, the patient has been managed on an outpatient basis for the last 3 years with good QOL and the cancer under control.
  • This case suggests that this combination therapy can be expected to be highly effective as a safe approach for continuously maintaining the QOL of patients with advanced or recurrent colorectal cancer.
  • [MeSH-major] Camptothecin / analogs & derivatives. Colonic Neoplasms / drug therapy. Colonic Neoplasms / pathology. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Oxonic Acid / therapeutic use. Pleurisy / drug therapy. Tegafur / therapeutic use
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Combinations. Humans. Male. Neoplasm Staging. Positron-Emission Tomography. Time Factors. Tomography, X-Ray Computed

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  • (PMID = 18347407.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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8. Miyake Y, Kato T, Katayama K, Doi T, Oshima K, Handa R, Hoshi M, Makari Y, Oshima S, Iijima S, Kurokawa E, Kikkawa N: [A case of ascending colon carcinoma metastasized to an inguinal hernia sac]. Gan To Kagaku Ryoho; 2007 Nov;34(12):2016-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of ascending colon carcinoma metastasized to an inguinal hernia sac].
  • We report a case of ascending colon cancer metastasized to an inguinal hernia sac.
  • A 60-year-old man, who was undergone a right hemicolectomy for an ascending colon cancer, was pointed out a palpable inguinal mass at one year and eight months after the operation.
  • In the operation, a tumor of the inguinal hernia sac, which invaded to spermatic cord, could be found and was removed with right testis.
  • Bassini's method was performed after the resection of the inguinal tumor.
  • Histological examination revealed that the tumor was metastasis of colon carcinoma.
  • As for the advanced colon cancer, we need to mention the possibility of metastatic saccular tumor.
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Humans. Male. Middle Aged. Neoplasm Metastasis / drug therapy. Neoplasm Metastasis / pathology. Tomography, X-Ray Computed

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  • (PMID = 18219884.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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9. mukai M, Moriya H, Himeno S, Oida Y, mukohyama S, Nishi T, Nakasaki H, Satoh S, Makuuchi H: Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases. Oncol Rep; 2001 Sep-Oct;8(5):1079-83
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  • [Title] Efficacy of oral UFT plus leucovorin therapy for colon cancer with ovarian and multiple liver metastases: report of two cases.
  • Case 1: a patient was diagnosed as having ascending colon cancer with right ovarian metastasis, and underwent palliative right hemicolectomy plus oophorectomy.
  • The tumor was a well-differentiated adenocarcinoma with right ovarian metastasis, and the disease was classified as stage IV.
  • Oral chemotherapy with UFT plus LV was performed for about 3 years, and the patient is still being followed up with no recurrence at 5 years postoperatively.
  • Case 2: a patient was diagnosed as having incomplete large bowel obstruction caused by ascending colon cancer, and underwent curative right hemicolectomy.
  • The tumor was a moderately differentiated adenocarcinoma, and the disease was classified as stage II.
  • Since multiple liver metastases developed at 3 months postoperatively, oral chemotherapy with UFT plus LV was started.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colonic Neoplasms / drug therapy. Leucovorin / therapeutic use. Liver Neoplasms / drug therapy. Ovarian Neoplasms / drug therapy. Tegafur / therapeutic use. Uracil / therapeutic use
  • [MeSH-minor] Administration, Oral. Adult. Aged. Aged, 80 and over. Colectomy. Female. Humans. Neoplasm Staging. Ovariectomy. Postoperative Period. Remission Induction. Tomography, X-Ray Computed


10. Chalkiadakis GE, Lasithiotakis KG, Petrakis I, Kourousis C, Georgoulias V: Major hepatectomy and right hemicolectomy at the time of primary cytoreductive surgery for advanced ovarian cancer: report of a case. Int J Gynecol Cancer; 2005 Nov-Dec;15(6):1115-9
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  • [Title] Major hepatectomy and right hemicolectomy at the time of primary cytoreductive surgery for advanced ovarian cancer: report of a case.
  • Major liver involvement at the time of diagnosis is a rare event in patients with ovarian cancer, and the issue of major hepatectomy at the time of primary cytoreductive surgery is controversial.
  • A computed tomography scan demonstrated bilateral ovarian masses, extending to the right iliac fossa, pressing the cecum-ascending colon.
  • The diagnosis of advanced ovarian cancer was clinically suspected; the patient underwent a total abdominal hysterectomy with bilateral salpingo-oophorectomy, right hemicolectomy, omentectomy, left lobectomy, deroofing, and draining of the cystic formation of the right liver lobe along with systematic pelvic and para-aortic lymphadenectomy.
  • Systemic chemotherapy (six cycles of paclitaxel/carboplatin) was subsequently administered, and after 15 months of follow-up period, the patient is still in first remission and alive.
  • Ovarian cancer with concomitant extensive right colon infiltration and hematogenous liver metastases can be successfully managed with aggressive surgical resection and postoperative chemotherapy in carefully selected patients.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Carboplatin / administration & dosage. Chemotherapy, Adjuvant. Female. Gynecologic Surgical Procedures. Humans. Lymph Node Excision. Middle Aged. Neoplasm Staging. Paclitaxel / administration & dosage. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16343191.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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11. Mazaki T, Mado K, Manmoto J, Okame H, Ishii Y, Suzuki K, Masuda H, Takayama T: [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11]. Gan To Kagaku Ryoho; 2008 Sep;35(9):1583-6
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  • [Title] [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11].
  • We report three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 with CPT-11.
  • Case 1: A total gastrectomy was performed for a gastric cancer located in the lower to upper body of the stomach (T3 (SE), N2, H0, P0, por 2, stage III B).
  • Abdominal computed-tomography (CT) revealed a solitary liver metastasis in the S8 subsegment of the liver.
  • We treated the patient with S-1 combined with CPT-11.
  • Case 2: Sigmoidectomy and partial resection of small intestine and abdominal wall were performed for sigmoid colon cancer.
  • After surgery, the patient was treated with S-1 combined with CPT-11.
  • Case 3: Laparoscopic right hemicolectomy was performed for ascending colon cancer (SE, N1, H0, P0, M0, tub 1, stage III a).
  • We treated the patient with S-1 combined with CPT-11.
  • [MeSH-major] Camptothecin / analogs & derivatives. Colonic Neoplasms / drug therapy. Colonic Neoplasms / pathology. Liver Neoplasms / secondary. Oxonic Acid / therapeutic use. Stomach Neoplasms / drug therapy. Stomach Neoplasms / pathology. Tegafur / therapeutic use
  • [MeSH-minor] Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Combinations. Female. Humans. Male. Middle Aged. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 18799916.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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12. Sato H, Maeda K, Kuroda M, Maruta M: Poorly differentiated adenocarcinoma in the ascending colon with peritoneal dissemination: case report of a patient who survived more than eleven years. Acta Gastroenterol Belg; 2008 Jul-Sep;71(3):321-4

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Poorly differentiated adenocarcinoma in the ascending colon with peritoneal dissemination: case report of a patient who survived more than eleven years.
  • We report herein a case of a patient with a poorly differentiated adenocarcinoma in the ascending colon with peritoneal dissemination who survived more than eleven years thanks to adjuvant chemotherapy.
  • Barium enema study and colonoscopy showed an ascending colon tumor.
  • Abdominal computed tomography showed extensive ascites and masses besides the ascending colon and in the upper abdomen.
  • A continuous infusion of 3000 mg of 5-fluorouracil per 48 hours was given weekly for four weeks followed by 450 mg of oral UFT-E (Uracil:Tegafur) per day as post-operative chemotherapy.
  • Although she underwent removal of a breast cancer eight years after the operation for colon cancer, no sign of tumor progression has been observed for 132 months since the initial operation, by taking UFT-E without any adverse events.

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  • (PMID = 19198579.001).
  • [ISSN] 1784-3227
  • [Journal-full-title] Acta gastro-enterologica Belgica
  • [ISO-abbreviation] Acta Gastroenterol. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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13. Li Q, Gao C, Juzi JT, Hao X: Analysis of 82 cases of retroperitoneal schwannoma. ANZ J Surg; 2007 Apr;77(4):237-40
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  • BACKGROUND: The aim of the study was to improve the diagnosis and treatment of retroperitoneal schwannoma by analysing clinical manifestations and postoperative course of this rare disease.
  • The interval between clinical manifestation and diagnosis ranged from 10 days to 2 years.
  • Only in 13 patients (15.9%) a correct preoperative diagnosis was made by either ultrasound-guided biopsy, computed tomography scanning or magnetic resonance imaging.
  • All patients received operative therapy.
  • Two patients (2.4%) had multiple schwannomas and two others had a simultaneous malignancy (adenocarcinoma of the ascending colon and squamous-cell carcinoma of the lung, respectively).
  • The tumour size ranged from 3 to 22 cm.
  • It is difficult to make an accurate preoperative diagnosis.
  • However, with the preoperative assessment of ultrasound-guided fine-needle aspiration, computed tomography and magnetic resonance imaging, the accuracy of diagnosis could definitely be improved.
  • Treatment depends solely on surgery.
  • Malignant schwannomas are insensitive to chemotherapy and radiation, resulting in poor prognosis.
  • [MeSH-major] Neurilemmoma / diagnosis. Neurilemmoma / surgery. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Diagnostic Imaging. Female. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local. Prognosis. Retrospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 17388825.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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14. Gan JL, Tang ZJ: [Clinical, endoscopic and pathological features of primary colorectal non-Hodgkin lymphoma: 24 cases report]. Zhonghua Wei Chang Wai Ke Za Zhi; 2006 Nov;9(6):502-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There were 6 cases (25.0%) involving two or more lesion sites, including three cases showing continuous skip-distribution from sigmoid colon to ascending colon, one case showing the homologous manifestation from rectum to cecum, one case involving ascending colon and rectum, and the last one involving sigmoid colon and rectum.
  • The major pathology types were diffuse large B-cell lymphoma (11/24, 45.8%), intestinal T-cell lymphoma (8/24, 33.3%), and mucosa-associated lymphoid tissue lymphoma (MALT) (3/24, 12.5%).
  • Sixteen postoperative patients accepted CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) or COP (cyclophosphamide, vincristine, prednisone) chemotherapy, and three patients abandoned treatment.
  • Diffuse large B-cell lymphoma and intestinal T-cell lymphoma are the main pathological types.
  • Comprehensive treatment of surgery and chemotherapy are effective methods for primary colorectal non-Hodgkin lymphoma.
  • [MeSH-minor] Adult. Aged. Biopsy. Endoscopy. Female. Follow-Up Studies. Humans. Lymphoma, T-Cell / diagnosis. Lymphoma, T-Cell / pathology. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. Young Adult

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  • (PMID = 17143795.001).
  • [ISSN] 1671-0274
  • [Journal-full-title] Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
  • [ISO-abbreviation] Zhonghua Wei Chang Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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15. Eisenkop SM, Spirtos NM, Friedman RL, Lin WC, Pisani AL, Perticucci S: Relative influences of tumor volume before surgery and the cytoreductive outcome on survival for patients with advanced ovarian cancer: a prospective study. Gynecol Oncol; 2003 Aug;90(2):390-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Relative influences of tumor volume before surgery and the cytoreductive outcome on survival for patients with advanced ovarian cancer: a prospective study.
  • METHODS: Patients (408) with stage IIIC epithelial ovarian cancer had cytoreductive surgery before systemic platinum-based combination chemotherapy.
  • (1) right upper quadrant (diaphragm/hepatic, and adjacent peritoneal surfaces), (2) left upper quadrant (omentum/gastro-colic ligament, spleen, stomach, transverse colon, splenic flexure of colon), (3) pelvis (reproductive organs, recto-sigmoid, pelvic peritoneum), (4) retroperitoneum (pelvic/aortic nodes), and (5) central abdomen (small bowel, ascending/descending colon, mesentery, anterior abdominal wall, pericolic gutters).
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Middle Aged. Neoplasm Staging. Prospective Studies. Survival Analysis. Treatment Outcome

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  • (PMID = 12893206.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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16. Liang JT, Lai HS, Lee PH: Laparoscopic medial-to-lateral approach for the curative resection of right-sided colon cancer. Ann Surg Oncol; 2007 Jun;14(6):1878-9

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic medial-to-lateral approach for the curative resection of right-sided colon cancer.
  • INTRODUCTION: Our previous randomized clinical trial comparing the laparoscopic medial-to-lateral dissection with the more classic lateral-to-medial approach for resection of rectosigmoid cancer showed that the medial approach reduces the operative time and the postoperative proinflammatory response.
  • Besides the oncologic advantages of an early vessel division and a "no-touch" dissection, we feel that the longer the lateral abdominal wall attachments of the colon are preserved, the better the exposure and the easier the dissection.
  • Encouraged by the above-mentioned positive findings, we therefore further conduct this phase II clinical trial to examine the feasibility and surgical outcomes regarding the utilization of this medial-to-lateral laparoscopic dissection approach for the curative resection of right-sided colon cancer.
  • METHODS: A total of 104 patients (from December 2000 to January, 2005) with advanced right-sided colon cancer (TNM stage II: n = 56; stage III: n = 48) requiring a curative right hemicolectomy were subjected to the laparoscopic medial-to-lateral approach that included initial exploration and ligation of ileocolic, right colic, and middle colic vessels in no-touch isolation fashion, subsequent medial-to-lateral extension of retroperitoneal dissection along Gerota fascia, opening of lesser sac by transection of gastrocolic ligament, and the final mobilization of hepatic flexure and lateral attachments of ascending colon (Fig. 1).
  • Postoperatively, adjuvant chemotherapy with Mayo Clinic Regimen was given in patients with stage III diseases.
  • RESULTS: The laparoscopic medial-to-lateral approach for a curative right hemicolectomy can be preformed with acceptable operation time (192.6 +/- 32.8 min, mean +/- standard deviation) and little blood loss (48.4 +/- 14.4 ml) through a small wound (6.0 +/- 0.8 cm).
  • During the follow-up periods (median: 30 months, range 6-55 months), recurrence of tumor developed in 6 (10.7%) of stage II and 10 (20.8%) of stage III patients, with liver metastasis in six patients, lung metastasis in 4, liver and lung metastasis in 1, intraperitoneal recurrence in 2, bone metastasis in 1, brain metastasis in 1, and port-site recurrence in 1.
  • [MeSH-major] Colectomy / methods. Colon, Ascending / surgery. Colonic Neoplasms / surgery. Laparoscopy / methods
  • [MeSH-minor] Blood Loss, Surgical. Chemotherapy, Adjuvant. Dissection / methods. Feasibility Studies. Follow-Up Studies. Hospitalization. Humans. Ileus / etiology. Ligaments / surgery. Ligation. Neoplasm Metastasis. Neoplasm Recurrence, Local / pathology. Neoplasm Staging. Pain, Postoperative / etiology. Postoperative Complications. Prospective Studies. Recovery of Function / physiology. Time Factors. Treatment Outcome

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  • (PMID = 17377832.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase II; Comparative Study; Journal Article
  • [Publication-country] United States
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17. Saito H, Watanuki A, Tabira Y, Ikeda N, Urakawa M, Sakano T: [Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report]. Gan To Kagaku Ryoho; 2009 Nov;36(11):1907-10

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report].
  • Computed tomography (CT) and colonoscopy (CF)revealed a huge ascending colon tumor, invading the descending part of the duodenum.
  • Tumor reduction was significant on the preoperative CT and CF, with the invasion to the duodenum obscured.
  • Resected specimen revealed residual tumor in a small area of the submucosal to proper muscular layer of the contracted ascending colon, without pathological invasion to the duodenum.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colectomy. Colonic Neoplasms / therapy
  • [MeSH-minor] Aged. Antimetabolites, Antineoplastic / administration & dosage. Antineoplastic Agents, Phytogenic / administration & dosage. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Colonoscopy. Combined Modality Therapy. Drug Combinations. Female. Humans. Oxonic Acid / administration & dosage. Tegafur / administration & dosage. Tomography, X-Ray Computed

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  • (PMID = 19920399.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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18. Nasu K, Umekita N, Noda K, Tanaka S, Maeshiro T, Miyamoto S, Inoue S, Arai K: [A case of recurrent colon cancer patient who gained a long-term survival by repeated and aggressive surgical resection]. Gan To Kagaku Ryoho; 2008 Nov;35(12):2150-2

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of recurrent colon cancer patient who gained a long-term survival by repeated and aggressive surgical resection].
  • We performed right hemicolectomy with liver S7 partial excision (a postoperative diagnosis of the hepatic lesion, adenoma) for ascending colon carcinoma of type 2 with hepatic metastasis.
  • Postoperative diagnosis was ss, n2, ly2, v2, Stage IIIb, based on the Japanese classification of colon cancer.
  • Twelve months after the first operation, she was developed intestinal atresia by an abdominal wall recurrence, and we performed the operation of abdominal wall mass resection with a partial resection of small bowel.
  • Afterwards she developed a recurrence three times in the abdominal wall or intra-abdominal lymph nodes during the next 1 year and six months, and we performed a local excision each time.
  • The pathological findings in reoperations were all metastasis from ascending colon carcinoma of primary operation.
  • After the final operation, we did not perform chemotherapy because the patient wished not to have it.
  • Recently, the therapy for recurrent colon cancer has been shifted to more effective chemotherapy such as FOLFOX or FOLFIRI regimen, and a surgical resection is becoming rare.
  • However, we experienced a case of recurrent colon cancer treated with four aggressive surgical resections that was beneficial for a long-term survival.
  • [MeSH-major] Colonic Neoplasms / surgery. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Female. Humans. Liver Neoplasms / secondary. Liver Neoplasms / surgery. Lymphatic Metastasis. Middle Aged. Positron-Emission Tomography. Time Factors. Tomography, X-Ray Computed

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  • (PMID = 19106553.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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19. Paulsen JE, Elgjo K: Effect of tumour size on the in vivo growth inhibition of human colon carcinoma cells (HT-29) by colon mitosis inhibitor. In Vivo; 2001 Sep-Oct;15(5):397-401
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of tumour size on the in vivo growth inhibition of human colon carcinoma cells (HT-29) by colon mitosis inhibitor.
  • We have previously shown that the colon mitosis inhibitor (CMI) suppresses the growth of transplanted HT-29 human colon carcinoma cells by approximately 40%.
  • However, this effect declined along the time-course, as the inoculums progressively grew larger.
  • In the present work we designed a test to assess the effectiveness of CMI as a function of tumour size.
  • After ranking the terminal tumours by ascending size in the control group and the CMI group the growth inhibition was calculated at each rank position.
  • The observed negative correlation between control tumour size and CMI inhibition (r = -0.94, p < 0.001) clearly demonstrated decreased growth inhibition with increased tumour size.
  • Furthermore, HT-29A4 displayed a similar tendency of decreased CMI effect with increased tumour size (r = -0.70, p < 0.001).
  • The apparent enhanced responsiveness among small tumours underlines the importance of early chemoprevention and chemotherapy.
  • [MeSH-major] Adenocarcinoma / pathology. Antineoplastic Agents / therapeutic use. Colonic Neoplasms / pathology. Growth Inhibitors / therapeutic use. Oligopeptides / therapeutic use
  • [MeSH-minor] Animals. Cell Division / drug effects. Clone Cells / drug effects. Clone Cells / transplantation. Disease Progression. Eflornithine / pharmacology. Eflornithine / therapeutic use. Humans. Mice. Mice, Inbred BALB C. Mice, Nude. Neoplasm Transplantation. Pyrrolidonecarboxylic Acid / analogs & derivatives. Tretinoin / pharmacology. Tretinoin / therapeutic use. Tumor Cells, Cultured / drug effects. Tumor Cells, Cultured / transplantation. Xenograft Model Antitumor Assays

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  • (PMID = 11695236.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Growth Inhibitors; 0 / Oligopeptides; 5688UTC01R / Tretinoin; 69275-10-1 / pyroglutamyl-histidyl-glycine; SZB83O1W42 / Pyrrolidonecarboxylic Acid; ZQN1G5V6SR / Eflornithine
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20. Benedix F, Meyer F, Kube R, Gastinger I, Lippert H: [Right- and left-sided colonic cancer - different tumour entities]. Zentralbl Chir; 2010 Aug;135(4):312-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Right- and left-sided colonic cancer - different tumour entities].
  • [Transliterated title] Karzinome des rechten und linken Kolons - verschiedene Tumorentitäten?
  • In the past two decades, a growing amount of data has been reported suggesting that carcinomas of the right and left colon should be considered as different tumour entities.
  • The aim of this review is to present a detailed analysis of the current knowledge regarding differences between right- and left-sided colon cancer and potential consequences for daily practice.
  • METHODS: For this report all articles with relevant information on differences between right- and left-sided colon carcinoma found via Pubmed searches were analysed.
  • RESULTS: Patients with right-sided colon cancer are significantly older, predominantly women, with a higher rate of comorbidities.
  • Histopathologically, carcinoma of the right colon show a higher percentage of poorly differentiated, locally advanced tumours with a higher rate of mucinous carcinoma and different pattern of metastatic spread.
  • CONCLUSIONS: The numerous findings regarding differences between right- and left-sided colon cancers should have an impact on colon cancer screening and therapy.
  • Firstly, there are defined risk groups which should receive complete colonoscopy, particularly if they present with symptoms suspicious for colon carcinoma.
  • Furthermore, location of the colon cancer should be considered before group stratification into genetic, clinical and especially chemotherapy trials.
  • A more tailored approach to colon cancer treatment would be highly desirable if future trials further support the hypothesis of two distinct tumour entities.
  • [MeSH-major] Colon, Ascending / surgery. Colon, Descending / surgery. Colonic Neoplasms / surgery
  • [MeSH-minor] Comorbidity. Female. Humans. Male. Neoplasm Staging. Prognosis. Survival Rate

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  • [Copyright] Georg Thieme Verlag Stuttgart ˙ New York.
  • (PMID = 20806133.001).
  • [ISSN] 1438-9592
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article; Review
  • [Publication-country] Germany
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21. Gundling F, Zillinger C, Schmidt T, Ingrisch H, Heitland W, Nerlich A, Schepp W: [A 67-year-old patient with diarrhoea and constipation without any pathological findings in virtual colonoscopy]. Z Gastroenterol; 2005 May;43(5):455-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] 67-jähriger Patient mit paradoxer Diarrhoe und unauffälliger virtueller Koloskopie.
  • Virtual colonoscopy provides a computer-simulated endoluminal perspective of the air-filled, distended colon using modern CT scanning (spiral CT).
  • After right hemicolectomy because of metastasised carcinoma of the ascending colon (pT4pN1pM1) we started palliative chemotherapy with oxaliplatin, 5-fluorouracil and leucovorin.
  • The risk of misdiagnosis by virtual colonoscopy is clearly increased in patients with subtotal tumour stenosis of the ascending colon.
  • Conventional video-colonoscopy remains the gold standard for the diagnosis of colorectal carcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Colonic Diseases / diagnosis. Colonic Neoplasms / diagnosis. Colonography, Computed Tomographic. Colonoscopy. Constipation / etiology. Diarrhea / etiology. Intestinal Obstruction / diagnosis. Video Recording
  • [MeSH-minor] Aged. Colon / pathology. Diagnostic Errors. Humans. Male. Neoplasm Staging


22. Wright CL, Stewart ID: Histopathology and mismatch repair status of 458 consecutive colorectal carcinomas. Am J Surg Pathol; 2003 Nov;27(11):1393-406
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with these tumors have an improved prognosis and may show greater sensitivity to chemotherapy.
  • MMR-d tumors presented at an earlier stage than intact tumors, and the node-positive MMR-d tumors were less likely than intact tumors to have pericolonic extranodal tumor deposits (18.2% vs. 44%).
  • The proportion of tumors at each site that were MMR-d increased progressively from cecum (32%) to ascending (35%) to transverse colon, where 41% of all tumors were defective.
  • Both types of MMR-d tumors more often had expansive borders, intraepithelial lymphocytosis, peritumoral lymphoid, and Crohn's-like lymphoid responses than the intact tumors; the frequencies of these features diminished with advancing stage.
  • Tumor budding was less common in stage II and III MMR-d tumors than in intact tumors.
  • Keloid and myxoid type stromas correlated with stage and vascular invasion and were not related to mismatch repair status.
  • [MeSH-minor] Adaptor Proteins, Signal Transducing. Adult. Aged. Aged, 80 and over. Carrier Proteins. Colon, Ascending / chemistry. Colon, Ascending / pathology. Colon, Descending / chemistry. Colon, Descending / pathology. DNA, Neoplasm / analysis. Female. Humans. Immunohistochemistry. Male. Middle Aged. MutS Homolog 2 Protein. Neoplasm Proteins / analysis. Neoplasm Proteins / genetics. Neoplasm Staging. Neoplasms, Second Primary. Nuclear Proteins. Proto-Oncogene Proteins / analysis. Proto-Oncogene Proteins / genetics

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  • (PMID = 14576472.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Carrier Proteins; 0 / DNA, Neoplasm; 0 / DNA-Binding Proteins; 0 / MLH1 protein, human; 0 / Neoplasm Proteins; 0 / Nuclear Proteins; 0 / Proto-Oncogene Proteins; EC 3.6.1.3 / MSH2 protein, human; EC 3.6.1.3 / MutS Homolog 2 Protein
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