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Items 1 to 31 of about 31
1. Sośnik K, Lewczuk J, Ludwik B, Kowal J, Sobkowicz B, Gwoźdź W, Wrabec K: [Cardiac tamponade due to angiosarcoma--was surgical treatment necessary? A case report]. Kardiol Pol; 2006 Dec;64(12):1426-7
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  • [Title] [Cardiac tamponade due to angiosarcoma--was surgical treatment necessary? A case report].
  • The decision to perform surgery, although controversial, allowed to diagnose cardiac angiosarcoma with metastases to pericardium, vena cava superior and pulmonary trunk.
  • Consequently, chemotherapy was instituted and was initially effective, however, the patient died 12 months later due to the progression of the disease.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Echocardiography. Female. Humans. Mediastinal Neoplasms / diagnosis. Mediastinal Neoplasms / secondary. Middle Aged. Pericardial Effusion / etiology. Pericardial Effusion / therapy. Tomography, X-Ray Computed. Treatment Outcome. Vascular Neoplasms / diagnosis. Vascular Neoplasms / secondary

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  • (PMID = 17206543.001).
  • [ISSN] 0022-9032
  • [Journal-full-title] Kardiologia polska
  • [ISO-abbreviation] Kardiol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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2. Koga S, Ikeda S, Urata J, Chijiwa R, Abe K, Hayashi T, Eishi K, Kohno S: Primary high-grade myofibroblastic sarcoma arising from the pericardium. Circ J; 2008 Feb;72(2):337-9
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  • [Title] Primary high-grade myofibroblastic sarcoma arising from the pericardium.
  • Echocardiography, computed tomography and magnetic resonance imaging revealed massive pericardial effusion and a large tumor in the pericardial cavity, attached to the pericardium of the left ventricular posterolateral free wall.
  • Because of local recurrence soon after surgery, the patient received adjuvant chemotherapy, including doxorubicin and ifosfamide, and subsequent radiotherapy.
  • As of 6 months after completing radiotherapy, the patient was alive and no disease progression or distant metastases were evident.
  • This may be the first report of primary high-grade myofibroblastic sarcoma arising from the pericardium.
  • [MeSH-major] Cardiac Tamponade / pathology. Cardiac Tamponade / therapy. Heart Neoplasms / pathology. Heart Neoplasms / therapy. Myosarcoma / pathology. Myosarcoma / therapy
  • [MeSH-minor] Antibiotics, Antineoplastic / administration & dosage. Antineoplastic Agents, Alkylating / administration & dosage. Combined Modality Therapy. Doxorubicin / administration & dosage. Humans. Ifosfamide / administration & dosage. Male. Middle Aged. Pericardial Effusion / pathology. Pericardial Effusion / therapy

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  • (PMID = 18219177.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Alkylating; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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3. Doval DC, Pande SB, Sharma JB, Rao SA, Prakash N, Vaid AK: Report of a case of pericardial mesothelioma with liver metastases responding well to pemetrexed and platinum-based chemotherapy. J Thorac Oncol; 2007 Aug;2(8):780-1
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  • [Title] Report of a case of pericardial mesothelioma with liver metastases responding well to pemetrexed and platinum-based chemotherapy.
  • Pericardial mesothelioma remains a disease with a bleak prognosis.
  • We report the case of a patient with metastases to liver and good response to pemetrexed and carboplatin-based combination chemotherapy and consequent prolonged progression-free survival.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Neoplasms / pathology. Liver Neoplasms / secondary. Mesothelioma / secondary. Pericardium

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  • (PMID = 17762349.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glutamates; 0 / Platinum Compounds; 04Q9AIZ7NO / Pemetrexed; 5Z93L87A1R / Guanine
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4. Balli A, Lachat M, Gerber B, Baumgartner C, Glaus T: [Cardiac tamponade due to pericardial mesothelioma in an 11-year-old dog: diagnosis, medical and interventional treatments]. Schweiz Arch Tierheilkd; 2003 Feb;145(2):82-7
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  • [Title] [Cardiac tamponade due to pericardial mesothelioma in an 11-year-old dog: diagnosis, medical and interventional treatments].
  • After partial pericardectomy by thoracoscopy and after obtaining a histological diagnosis of mesothelioma adjuvant intracavitary chemotherapy using cisplatin was performed.
  • Already one week later the dog developed marked dyspnea due to severe pleural effusion.
  • Despite extensive treatments life span from initial presentation to euthanasia was only 5 months.
  • Necropsy revealed extensive mesothelioma metastases covering the whole pleura, epicardium and remaining pericardium.
  • Diagnostic and therapeutic aspects of (recurrent) pericardial effusion are discussed based on this case.
  • [MeSH-minor] Animals. Diagnosis, Differential. Dogs. Euthanasia, Animal. Fatal Outcome. Male. Pericardial Effusion / etiology. Pericardial Effusion / therapy. Pericardial Effusion / veterinary. Pericardiectomy / veterinary. Pericardiocentesis / veterinary. Pleural Effusion, Malignant / etiology. Pleural Effusion, Malignant / therapy. Pleural Effusion, Malignant / veterinary. Recurrence

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  • (PMID = 12649954.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Switzerland
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5. Kim HS, Park NH, Kang SB: Rare metastases of recurrent cervical cancer to the pericardium and abdominal muscle. Arch Gynecol Obstet; 2008 Nov;278(5):479-82
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  • [Title] Rare metastases of recurrent cervical cancer to the pericardium and abdominal muscle.
  • During the post-operative follow-up period of 6 months, pericardial and abdominal muscular metastases were developed along with the symptoms of dry cough and dyspnea.
  • Although palliative radiation therapy and chemotherapy were performed for the control of the metastases, she expired due to cardiac failure 16 months after the operation.
  • The prognosis of patients with pericardial and abdominal wall metastases from recurrent cervical cancer is usually poor because of the systemic dissemination of the disease.
  • Aggressive local and systemic treatments may provide significant palliation of associated symptoms.
  • [MeSH-major] Abdominal Muscles. Abdominal Neoplasms / secondary. Carcinoma, Squamous Cell / secondary. Heart Neoplasms / secondary. Pericardium. Uterine Cervical Neoplasms / pathology


6. Mayer F, Aebert H, Rudert M, Königsrainer A, Horger M, Kanz L, Bamberg M, Ziemer G, Hartmann JT: Primary malignant sarcomas of the heart and great vessels in adult patients--a single-center experience. Oncologist; 2007 Sep;12(9):1134-42
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  • RESULTS: Tumors were located in the left ventricle (n = 3), left/right atrium (n = 2/3), pulmonary artery (n = 2), and ventricular septum, aorta, pericardium, and inferior vena cava (n = 1 each).
  • Six patients presented with distant metastases to the lungs (n = 5), lymph nodes (n = 2), and liver (n = 1).
  • Of those, two developed local recurrence within 2 and 10 months from surgery.
  • Eleven patients received palliative chemotherapy, seven of those as initial treatment.
  • Eight patients attained a response to treatment, two had disease stabilization for 6 and 12 months.
  • Given the promising response to chemotherapy, an optimized treatment approach including neoadjuvant chemo-/radiotherapy in patients with locally advanced disease should be pursued.
  • [MeSH-minor] Adult. Aortic Diseases / epidemiology. Female. Follow-Up Studies. Germany / epidemiology. Hemangiosarcoma / epidemiology. Humans. Leiomyosarcoma / epidemiology. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Neoadjuvant Therapy / statistics & numerical data. Pulmonary Artery / pathology. Remission Induction. Retrospective Studies. Survival Rate. Venae Cavae / pathology

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  • (PMID = 17914083.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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7. Karpuz V, Ikitimur B, Karpuz H: [A survey of heart tumors: clinical and echocardiographic approach]. Anadolu Kardiyol Derg; 2007 Dec;7(4):427-35

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  • Heart tumors may involve myocardium, endocardium, epicardium, pericardium, or any combination of the aforementioned layers.
  • On the other hand, the usual site for metastasis to the heart is the pericardium.
  • Magnetic resonance imaging and computerized tomography may be helpful for selected cases.
  • Surgery is the principal therapeutic option in benign tumors and when recurrences are not taken into account, they have favorable prognoses.
  • Since surgical resection is usually incomplete in malignant tumors, therapy must be individualized for each patient; even with adjuvant chemotherapy, postoperative survival is usually short.
  • Metastases to the heart are usually approached symptomatically except for exceptional cases.
  • [MeSH-minor] Echocardiography, Transesophageal. Fibroma / diagnosis. Fibroma / pathology. Fibroma / radiography. Fibroma / ultrasonography. Hemangioma / diagnosis. Hemangioma / pathology. Hemangioma / radiography. Hemangioma / ultrasonography. Humans. Magnetic Resonance Imaging. Myoma / diagnosis. Myoma / pathology. Myoma / radiography. Myoma / ultrasonography. Myxoma / diagnosis. Myxoma / pathology. Myxoma / radiography. Myxoma / ultrasonography. Tomography, X-Ray Computed

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  • (PMID = 18065342.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 49
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8. Larsen CR, Hansen PB, Clausen NT: Aggressive growth of epithelial carcinomas following treatment with nucleoside analogues. Am J Hematol; 2002 May;70(1):48-50
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  • [Title] Aggressive growth of epithelial carcinomas following treatment with nucleoside analogues.
  • Two patients, one with B-cell chronic lymphocytic leukemia (CLL) and one with hairy-cell leukemia (HCL), were treated with immunosuppressive chemotherapy.
  • During the fludarabine treatment, the patient developed a local SCC relapse and metastases in the neck.
  • The carcinoma was treated by excision and radiotherapy, and further fludarabine treatment was withheld.
  • Nevertheless, the SCC metastasized aggressively and the patient died 3 months after the start of fludarabine treatment, primarily due to respiratory failure.
  • The autopsy revealed heavy SCC infiltrations involving the lungs, pleura, mediastinum, pericardium, and liver.
  • At the time of diagnosis of HCL, the patient had two solid tumors in the liver containing poorly differentiated epithelial carcinoma cells of unknown origin.
  • During treatment with 2-chlorodeoxyadenosine (2CdA), the tumors in the liver rapidly spread in multiple intrahepatic metastases, followed by liver failure and death within 1 month.
  • [MeSH-major] 2-Chloroadenosine / therapeutic use. Antineoplastic Agents / therapeutic use. Immunosuppressive Agents / therapeutic use. Leukemia, Hairy Cell / drug therapy. Leukemia, Lymphocytic, Chronic, B-Cell / drug therapy. Liver Neoplasms / drug therapy. Nucleosides / therapeutic use. Vidarabine / therapeutic use

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  • [Copyright] Copyright 2002 Wiley-Liss, Inc.
  • (PMID = 11994981.001).
  • [ISSN] 0361-8609
  • [Journal-full-title] American journal of hematology
  • [ISO-abbreviation] Am. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Immunosuppressive Agents; 0 / Nucleosides; 146-77-0 / 2-Chloroadenosine; FA2DM6879K / Vidarabine; P2K93U8740 / fludarabine
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9. Yu L, Gu TX, Shi EY, Xiu ZY, Fang Q: [Diagnosis and therapy of primary malignant tumors of the heart and pericardium]. Zhonghua Zhong Liu Za Zhi; 2009 Mar;31(3):230-2
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  • [Title] [Diagnosis and therapy of primary malignant tumors of the heart and pericardium].
  • OBJECTIVE: To summarize and analyze the experience in diagnosis and treatment of primary malignant tumors of the heart and pericardium.
  • METHODS: The clinical data of 24 patients with malignant tumors of the heart and pericardium treated in our hospital between Jun.
  • RESULTS: All 24 patients received surgical treatment.
  • One patient died of cardiopulmonary failure in early postoperative stage and all the other patients died within 4 years after operation due to recurrence or metastases.
  • Early diagnosis and surgical resection of the tumor as complete as possible, and combination with post-operative radiotherapy and/or chemotherapy may improve the survival of the patients.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Follow-Up Studies. Humans. Male. Middle Aged. Myxoma / diagnosis. Myxoma / surgery. Pericardium / surgery. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 19615268.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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10. Moreno-Vega AL, Fuentes-Pradera J, Gordón-Santiago Mdel M, Vargas-Machuca JC: Intraventricular metastases from rectal-sigmoid adenocarcinoma. Clin Transl Oncol; 2006 Apr;8(4):296-7
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  • [Title] Intraventricular metastases from rectal-sigmoid adenocarcinoma.
  • The new diagnostic technology and more effective chemotherapy schedules for primary tumours, leading to a longer survival, have increased the frequency of such tumors.
  • Adenocarcinoma accounted for around 40% of all metastases to the heart; the most frequently involved sites are pericardium and epicardium.
  • We present a patient with an unusual intraventricular metastases from adenocarcinoma of rectal-sigmoid origin.
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Capecitabine. Cardiac Tamponade / etiology. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Dyspnea / etiology. Fatal Outcome. Female. Fluorouracil / analogs & derivatives. Heart Ventricles / diagnostic imaging. Humans. Liver Neoplasms / secondary. Organoplatinum Compounds / administration & dosage. Palliative Care. Radiography. Ultrasonography

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  • [Cites] Int J Cardiovasc Imaging. 2005 Feb;21(1):115-31 [15915945.001]
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  • (PMID = 16648108.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; 04ZR38536J / oxaliplatin; 0W860991D6 / Deoxycytidine; 6804DJ8Z9U / Capecitabine; U3P01618RT / Fluorouracil
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11. Sarjeant JM, Butany J, Cusimano RJ: Cancer of the heart: epidemiology and management of primary tumors and metastases. Am J Cardiovasc Drugs; 2003;3(6):407-21
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  • [Title] Cancer of the heart: epidemiology and management of primary tumors and metastases.
  • The pericardium can be the site of benign and malignant cardiac tumors, though metastatic tumors occur here far more commonly than do primary tumors.
  • Successful treatment for benign cardiac tumors is usually achieved by surgical resection.
  • Primary cardiac lymphoma may be successfully treated by chemotherapy.
  • Symptoms of cardiac metastases vary, and they depend on the site and extent of the lesions.
  • Treatment varies depending on the pathology of the primary tumor.
  • However, the aim of treatment is usually symptomatic relief.
  • With the advent of AIDS, Kaposi's sarcoma and high grade B cell lymphomas have also been identified in cardiac tissue.
  • The aim of this article is to review the epidemiology, clinical presentation, pathology and treatment of cardiac tumors.
  • [MeSH-minor] Acquired Immunodeficiency Syndrome / complications. Carcinoid Heart Disease / diagnosis. Carcinoid Heart Disease / pathology. Hematologic Neoplasms / diagnosis. Hematologic Neoplasms / pathology. Humans. Neoplasm Metastasis. Pericardium / pathology

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  • (PMID = 14728061.001).
  • [ISSN] 1175-3277
  • [Journal-full-title] American journal of cardiovascular drugs : drugs, devices, and other interventions
  • [ISO-abbreviation] Am J Cardiovasc Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
  • [Number-of-references] 62
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12. Chrissos DN, Stougiannos PN, Mytas DZ, Katsaros AA, Andrikopoulos GK, Kallikazaros IE: Multiple cardiac metastases from a malignant melanoma. Eur J Echocardiogr; 2008 May;9(3):391-2
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  • [Title] Multiple cardiac metastases from a malignant melanoma.
  • Metastatic tumors in the pericardium or the heart are more common than primary tumors and their incidence has increased during the last decades due to the prolonged survival of patients with cancer and the increased prevalence of the disease in the general population.
  • The echo study identified multiple metastases in the heart involving the pericardium, the myocardium and the right atrium, where the tumor was mobile creating mechanical tricuspid valve stenosis.
  • Malignant metastasis was confirmed by pericardiocentesis and, although treatment with chemotherapy was promptly initiated, the patient died 4 months later.
  • Despite the difficulty in clinical diagnosis of cardiac melanoma, early detection has important therapeutic and prognostic implications.

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  • (PMID = 17347051.001).
  • [ISSN] 1532-2114
  • [Journal-full-title] European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
  • [ISO-abbreviation] Eur J Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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13. Liu LY, Zhang WZ, Guan J, Tong WC, Cai SX, Shen XB, Hou CC: [Lung cancer in pregnancy: report of two cases and review of literature]. Zhonghua Jie He He Hu Xi Za Zhi; 2010 Nov;33(11):844-8
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  • METHODS: the clinical presentations, diagnosis and treatment of 2 cases of lung cancer in pregnancy were reported, and related literatures were reviewed.
  • RESULTS: The first case was a 31-year-old pregnant woman at 34(th)-week gestation, who presented with right sided pleural effusion on a Chest X-ray film.
  • Her respiratory condition worsened after the Caesarian section, and so mechanical ventilation, antibiotics and gefitinib were administered, but the treatment failed.
  • She died on the 28(th) day after Caesarian section.
  • PET showed right lung cancer with metastases to the pericardium, right pleura, liver and pelvic cavity.
  • After pregnancy termination, the patient received 2 cycles of chemotherapy consisting of cisplatin and etoposide.
  • To improve the prognosis and prevent the metastasis to the fetus, systemic therapy should be considered, and meanwhile maternal advantage must be always weighed against possible embryo-fetal risks.

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  • (PMID = 21211373.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
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14. Pigott C, Welker M, Khosla P, Higgins RS: Improved outcome with multimodality therapy in primary cardiac angiosarcoma. Nat Clin Pract Oncol; 2008 Feb;5(2):112-5
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  • [Title] Improved outcome with multimodality therapy in primary cardiac angiosarcoma.
  • BACKGROUND: A 37-year-old man presented with a history of hemoptysis and associated fever, chills, night sweats, and weight loss.
  • DIAGNOSIS: Primary cardiac angiosarcoma of the right atrium with systemic metastases to the pericardium, superior vena cava, and lungs.
  • MANAGEMENT: Neoadjuvant and adjuvant chemotherapy with doxorubicin and complete surgical resection of the tumor with reconstruction of the right atrium using bovine pericardium.
  • [MeSH-major] Antibiotics, Antineoplastic / therapeutic use. Doxorubicin / therapeutic use. Heart Neoplasms / drug therapy. Heart Neoplasms / surgery. Hemangiosarcoma / drug therapy. Hemangiosarcoma / surgery
  • [MeSH-minor] Adult. Animals. Cattle. Chemotherapy, Adjuvant. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Neoplasm Metastasis. Reconstructive Surgical Procedures

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  • (PMID = 18235443.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 80168379AG / Doxorubicin
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15. Oechsle K, Aebert H, Teichmann R, Budach W, Kanz L, Ziemer G, Hartmann JT: Primary malignant sarcomas of the heart and great vessels - a single center experience. J Clin Oncol; 2004 Jul 15;22(14_suppl):9044

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  • All pts were symptomatic with reduction of vitality, anorexia, dyspnoea, or neurological symptoms at the time of reception.
  • Tumors were located in atrium [(n=5), left (3)/right (2)], Art. pulmonalis (n=3), Aorta (n=2), pericardium or left chamber, (n=1 each).
  • Three out of 5 pts with curative intended surgery have subsequently developed recurrence within 6, 8 and 25 mos despite adjuvant treatment.
  • Palliative chemotherapy including adriamycin and ifosfamide has been applied in 7 pts and 4 pts attained some response to treatment (n=1 PR, n=3 SD).
  • Palliative radiation included 3 pts with brain metastases and a single pt with progressive primary tumor.
  • These pts should preferentially be referred to a tertiary Cancer Center immediately after diagnosis without preceding treatment attempts.
  • Although the majority of pts cannot be treated curatively due to the delay in diagnosis, an optimized treatment approach including neoadjuvant chemo-/radiotherapy might enhanced the rate of complete resection depending on the histological subtype and responsiveness to treatment.

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  • (PMID = 28013704.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Jaffe N: Pediatric osteosarcoma pneumonectomy for pulmonary metastases: Is it justified? J Clin Oncol; 2004 Jul 15;22(14_suppl):8565

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric osteosarcoma pneumonectomy for pulmonary metastases: Is it justified?
  • : 8565 Background:Over the past 25 years, 95 of 210 patients (pts) under 20 years of age were subjected to surgical procedures for resection of pulmonary metastases (PM).
  • Interval from diagnosis to detection of PM ranged from 1.5 to 2 yrs.
  • Pts were considered candidates for CPN provided the following criteria were met:.
  • 1) Despite responses, all PM could not be eradicated with chemotherapy;.
  • After CPN additional chemotherapy administered.
  • Four pts were also treated with radiation therapy (45-50 Gy) to sites of suspected residual microscopic disease with methotrexate to potentiate radiotherapeutic effect.
  • Second pt: tumor invasion into hilar lymph nodes and pericardium.
  • Important indications appear to be inability to eradicate PM by chemotherapy and inability to perform wedge resection or lobectomy.

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  • (PMID = 28013873.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Papi M, Genestreti G, Tassinari D, Lorenzini P, Serra S, Ricci M, Pasquini E, Nicolini M, Pasini G, Tamburini E, Fattori PP, Ravaioli A: Malignant pericardial mesothelioma. Report of two cases, review of the literature and differential diagnosis. Tumori; 2005 May-Jun;91(3):276-9
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  • The presentation of pericardial mesothelioma is aspecific and pathologically mesothelioma is not the most common among primary tumors of the pericardium.
  • Antemortem diagnosis is difficult and distant metastases are extremely rare.
  • The treatment for advanced primary pericardial mesothelioma is usually palliative because the tumor is resistant to radiotherapy and chemotherapy.
  • In this paper we report two cases of patients with primary mesothelioma of the pericardium without a definite history of asbestos exposure.
  • [MeSH-major] Heart Neoplasms / pathology. Mesothelioma / pathology. Pericardium / pathology

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  • (PMID = 16206657.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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18. Orski J, Telesińska D, Curyło A, Grodzicki T: [Cardiac tamponade as the first clinical manifestation of squamous cell carcinoma]. Przegl Lek; 2002;59(2):121-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient underwent a pericardio-centesis.
  • Due to the expansion of the process within the bronchus, the patient underwent chemotherapy according to the Taxol + Carboplatine scheme.
  • After 8 months of treatment the patient was hospitalized again due to a further increase in fluid in the pericardium, and symptoms of cardiac insufficiency which lead to patient death.
  • Autopsy revealed neoplastic change within the pericardium (fibrinous-hemorrhagic pericarditis and hemopericardium).
  • Squamous cell carcinoma metastases may be the cause of pericardial effusion, which is associated with poor prognosis.
  • [MeSH-major] Carcinoma, Squamous Cell / complications. Carcinoma, Squamous Cell / diagnosis. Cardiac Tamponade / etiology. Heart Neoplasms / complications. Heart Neoplasms / diagnosis. Pericardium
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols. Autopsy. Carboplatin / administration & dosage. Diagnosis, Differential. Fatal Outcome. Humans. Male. Middle Aged. Paclitaxel / administration & dosage

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  • (PMID = 12152250.001).
  • [ISSN] 0033-2240
  • [Journal-full-title] Przegla̧d lekarski
  • [ISO-abbreviation] Prz. Lek.
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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19. Khalil LY, Szturmowicz M, Wawrzyńska L, Fijałkowska A, Kupis W, Maszkowska-Kopij K, Szczepulska E, Burakowska B, Tomkowski W, Torbicki A: [Diagnostic difficulties in primary mesothelioma]. Pneumonol Alergol Pol; 2004;72(5-6):221-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A 54-year-old woman with a history of fatigue and shortness of breath was found to have a pericardial effusion and mild mediastinal lymphadenopathy.
  • Video-assisted pericardioscopy revealed thickened pericardium studded with multiple nodules.
  • As lung cancer is one of the most frequent causes of pericardial metastases the patient was treated with cisplatin and vinblastin.
  • Following 5 courses of chemotherapy--given over a 4 month period--the amount of pericardial effusion and pericardial thickness did not change.
  • The final diagnosis was primary pericardial mesothelioma of epithelioid type.
  • [MeSH-major] Heart Neoplasms / diagnosis. Mesothelioma / diagnosis. Pericardial Effusion / etiology. Pericardium
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 15757264.001).
  • [ISSN] 0867-7077
  • [Journal-full-title] Pneumonologia i alergologia polska
  • [ISO-abbreviation] Pneumonol Alergol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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20. Kataoka M, Shigemitsu K, Tanabe S, Ohara T, Takahata T, Nose S: Sudden death from metastatic esophageal cancer to the ventricular septum. Jpn J Thorac Cardiovasc Surg; 2005 Jul;53(7):365-8
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  • He complained of anorexia three months after the operation and was found to have multiple liver and mediastinal lymph node metastases.
  • He was admitted for chemotherapy.
  • Before starting chemotherapy, he suddenly died without any sign of hemorrhage or respiratory disorder.
  • No direct invasion from the pericardium was observed.

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  • [Cites] Cancer. 1990 Mar 15;65(6):1456-9 [2306690.001]
  • [Cites] J Am Med Assoc. 1953 Oct 24;153(8):712-5 [13096280.001]
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  • (PMID = 16095236.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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21. Raney RB, Anderson JR, Andrassy RJ, Crist WM, Donaldson SS, Maurer HM, Intergroup Rhabdomyosarcoma Study Group: Soft-tissue sarcomas of the diaphragm: a report from the Intergroup Rhabdomyosarcoma Study Group from 1972 to 1997. J Pediatr Hematol Oncol; 2000 Nov-Dec;22(6):510-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soft-tissue sarcomas of the diaphragm: a report from the Intergroup Rhabdomyosarcoma Study Group from 1972 to 1997.
  • RESULTS: Localized, gross residual disease after initial surgery was present in 10 patients, and five had metastases at diagnosis (pleura, 3; pericardium, 1; lungs and bones, 1).
  • Treatment consisted of radiation therapy to the primary tumor and metastases when feasible, and combination chemotherapy with vincristine, actinomycin D, and cyclophosphamide with or without doxorubicin, ifosfamide, cisplatin, and etoposide.
  • However, the other 10 patients experienced relapse at 0.3 to 2 years from start of therapy (median, 1 yr).
  • Treatment with more effective primary chemotherapy to shrink the tumor, followed-up by surgical resection and radiation therapy, should improve the prognosis for patients with sarcomas arising in the diaphragm, especially for the majority who have localized tumors.
  • [MeSH-major] Muscle Neoplasms / therapy. Rhabdomyosarcoma / therapy
  • [MeSH-minor] Adolescent. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Child, Preschool. Diaphragm. Female. Humans. Infant. Male. Radiotherapy Dosage. Recurrence. Retrospective Studies. Survival Rate

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  • (PMID = 11132218.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA-24507; United States / NCI NIH HHS / CA / CA-72989
  • [Publication-type] Journal Article; Multicenter Study; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
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22. Ishibashi N, Mitachi Y, Sugawara S, Shinozaki S, Miura M, Fukuju T, Katahira Y, Koyama K, Fujikawa N, Kato T, Murakami K: [A case of cardiac angiosarcoma successfully treated with docetaxel]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1849-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor was hen-egg sized and unresectable because of the invasion of the pericardium, the right ventricular wall and the superior vena cava.
  • The patient agreed to chemotherapy with docetaxel, which is known to be often effective against angiosarcoma of the scalp or face.
  • The chemotherapy was suspended for 8 months because of neutropenia and general fatigue as side effects of docetaxel.
  • Following treatments with paclitaxel, IL-2 and CPT-11 were ineffective for the primary tumor and liver metastases.
  • An effective treatment for cardiac angiosarcoma has not yet been established.
  • Chemotherapy with docetaxel should be considered in the treatment of patients with cardiac angiosarcoma.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Heart Neoplasms / drug therapy. Hemangiosarcoma / drug therapy. Taxoids / therapeutic use
  • [MeSH-minor] Drug Administration Routes. Drug Resistance, Neoplasm. Heart Atria. Humans. Liver Neoplasms / secondary. Male. Middle Aged

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  • (PMID = 18030022.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Taxoids; 15H5577CQD / docetaxel
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23. Díaz ML, Villanueva A, Bastarrika G, Zudaire B, del Barrio LG, Noguera JJ: Non-electrocardiogram-gated multidetector-row computed tomography findings of cardiac pathology in oncologic patients. Curr Probl Diagn Radiol; 2009 Sep-Oct;38(5):206-17
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-electrocardiogram-gated multidetector-row computed tomography findings of cardiac pathology in oncologic patients.
  • Multidetector-row computed tomography (MDCT) plays an essential role in oncologic imaging as the modality of mapping out the treatment strategy at staging, assessing response to the treatment, and following up patient outcome after the treatment.
  • In the group of oncologic patients, different tumoral and non-tumoral-related heart disorders can be found, for example, metastatic cardiac involvement (approximately 10% of patients with lung or breast cancer will develop metastases to the heart), paraneoplastic cardiac disorders, non-tumor-related heart disorders, and chemotherapy- and radiotherapy-related cardiac side effects.
  • MDCT plays a role in the detection of these entities.
  • An adequate knowledge of the patient's medical history, previous treatments, and concomitant illnesses is essential to interpret heart findings in oncologic patients who undergo MDCT.
  • [MeSH-major] Heart Diseases / complications. Heart Diseases / radiography. Heart Neoplasms / radiography. Heart Neoplasms / secondary. Neoplasms / pathology. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Carcinoid Heart Disease / radiography. Humans. Lung Neoplasms / radiography. Lung Neoplasms / secondary. Male. Melanoma / radiography. Neoplasm Invasiveness. Neoplasm Staging. Pericardial Effusion / etiology. Pericardial Effusion / radiography. Pericardium. Prostatic Neoplasms / complications. Retrospective Studies

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  • (PMID = 19632498.001).
  • [ISSN] 1535-6302
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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24. Ang P, Tan EH, Leong SS, Koh L, Eng P, Agasthian T, Cheah FK: Primary intrathoracic malignant effusion: a descriptive study. Chest; 2001 Jul;120(1):50-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • STUDY OBJECTIVES: Patients must fulfill the following criteria before a diagnosis of PIME can be made: clinical presentation dominated by pleural/pericardial effusion; histologic proof of malignancy obtained from the pleura and/or pericardium; no definite primary site in the lungs or elsewhere from CT scan of the chest, chest radiograph, or physical and endoscopic examination; no history of malignancy; and no history of asbestos exposure.
  • METHODS: We conducted a retrospective search of our database of patients who were referred to the Department of Medical Oncology with a diagnosis of pleural/pericardial effusion from January 1993 to January 2000.
  • RESULTS: Seventy-one of 200 patients from our database met the criteria.
  • The majority of patients (63%) had disease localized to the intrathoracic serosal surfaces; the rest had distant metastases involving the lung (50%), bone (27%), liver (19%), brain (8%), and skin (4%).
  • Six patients had two or more sites of distant metastases.
  • The median survival was 10 months for patients with disease localized to the pleura/pericardium and 7 months for those with distant metastases.
  • Thirty-eight patients (54%) received chemotherapy.
  • All had platinum-based chemotherapy, except for three patients.
  • The median survival for patients treated or not treated with chemotherapy was 12 months and 5 months, respectively.
  • Platinum-based chemotherapy may have a positive biological effect on this disease.
  • More studies are required to elucidate the epidemiology, possible etiologic factors, and treatment options for this group of patients.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Female. Humans. Male. Middle Aged. Retrospective Studies. Smoking. Survival Rate

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  • (PMID = 11451815.001).
  • [ISSN] 0012-3692
  • [Journal-full-title] Chest
  • [ISO-abbreviation] Chest
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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25. Reed E, Zerbe CS, Brawley OW, Bicher A, Steinberg SM: Analysis of autopsy evaluations of ovarian cancer patients treated at the National Cancer Institute, 1972-1988. Am J Clin Oncol; 2000 Apr;23(2):107-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Between 1972 and 1988, more than 500 women were treated for ovarian cancer at the National Cancer Institute in Bethesda, Maryland on approved experimental treatment protocols.
  • By comparison with the literature, the demographics of the cohort did not differ from previously published reports, other than the extent of chemotherapy received antemortem.
  • The median number of treatments regimens received was two (range, 1-6).
  • The pattern of disease spread at autopsy was different from that in previously published work in that there was a higher proportion of patients with disease found in liver parenchyma, lung pleura, and the pericardium.
  • Patients who received cisplatin as part of their initial treatment regimen had a higher incidence of metastases to the adrenal glands, thoracic nodes, bladder, and liver parenchyma, which was not explained by differences in survival.
  • Median survival for patients who received cisplatin as part of their initial therapy was 15.6 months, compared with a median of 15.4 months for patients who did not.
  • These data suggest a changing pattern of disease spread in patients with ovarian cancer receiving aggressive chemotherapy.
  • This may be caused by some effect of platinum-based therapy on the metastatic potential of the tumor.
  • [MeSH-minor] Adult. Aged. Antineoplastic Agents / therapeutic use. Cisplatin / therapeutic use. Cohort Studies. Demography. Female. Humans. Middle Aged. Neoplasm Metastasis. Retrospective Studies. Survival Analysis

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  • (PMID = 10776968.001).
  • [ISSN] 0277-3732
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antineoplastic Agents; Q20Q21Q62J / Cisplatin
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26. Rafajlovski S, Tatić V, Ilić S, Kanjuh V: [Frequency of metastatic tumors in the heart]. Vojnosanit Pregl; 2005 Dec;62(12):915-20

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The aim of this study was to analyze the frequency of metastatic tumors of the heart, their primary localization, as well as the localization of the metastases found in the autopsic material within the period 1972-2004.
  • METHODS: During the autopsy of the patients died of metastatic tumors, we microscopically and macroscopically analyzed all the organs and tissues to determine the metastases of primary tumors in other organs, especially in the heart and pericardium.
  • The most frequent metastases in the heart were caused by pulmonary carcinoma (18 cases), leukemia and malignant lymphoma (8 cases, each), then pancreatic and breast carcinoma, while the metastases of other carcinomas were rather rare.
  • In 40 (60.76%) cases, the metastasis was localized in the myocardium, but more often in the left ventricle, in 24 (30.38%) cases in the pericardium, in 4 cases in the epicardium and in the 3 of them in the mitral and tricuspid valve.
  • The methods of choice for the diagnosis of the metastasis in the heart are echocardiography, computerized tomography, magnetic resonance imaging, cytological analysis of the pericardial effusion and biopsy.
  • The treatment includes surgery, chemotherapy and radiotherapy.

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  • (PMID = 16375220.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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27. Shimoyama T, Yoshiya K, Yamato Y, Koike T, Honma K: Long-term survival after removal of a malignant peripheral nerve sheath tumor originating in the anterior mediastinum. Gen Thorac Cardiovasc Surg; 2009 Jun;57(6):310-4
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  • A computed tomography-guided percutaneous needle biopsy revealed only fibrosis.
  • The tumor was completely excised via a median sternotomy with partial resection of the pericardium and right upper lobe of the lung.
  • Thereafter, the tumor was diagnosed as a storiform-pleomorphic type of malignant fibrous histiocytoma.
  • No recurrence was found up to 5 years after the second surgery without adjuvant chemotherapy or radiation therapy.
  • However, he died from multiple lung metastases after 6 years.
  • [MeSH-minor] Aged. Biopsy, Needle. Fatal Outcome. Humans. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Male. Thoracotomy. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19533278.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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28. Musch E, Gremmler B, Nitsch J, Rieger J, Malek M, Chrissafidou A: Intrapericardial instillation of mitoxantrone in palliative therapy of malignant pericardial effusion. Onkologie; 2003 Apr;26(2):135-9
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  • [Title] Intrapericardial instillation of mitoxantrone in palliative therapy of malignant pericardial effusion.
  • BACKGROUND: Pericardial effusions occurring with pericardial or myocardial metastases often cause serious complications, necessitating temporary or emergency relief by percutaneous pericardiocentesis.
  • For long-term therapy success, the intrapericardial instillation of anti-neoplastic agents is an alternative to surgical methods, which are stressful for the patient.
  • Following our positive experiences with mitoxantrone in the treatment of malignant pleural effusions, we applied this substance for the therapy of malignant pericardial effusions.
  • Responses were evaluated by echocardiography 30 days after completion of therapy.
  • CONCLUSION: Intrapericardial instillation of mitoxantrone is a feasible and effective palliative method for the control of malignant pericardial effusions with little strain on the patients, short duration of hospital stay, cytotoxic characteristics of the substance with a correspondingly high rate of response and low side effects.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Breast Neoplasms / drug therapy. Heart Neoplasms / secondary. Mitoxantrone / administration & dosage. Palliative Care. Pericardial Effusion / drug therapy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Dose-Response Relationship, Drug. Drug Administration Schedule. Echocardiography. Feasibility Studies. Female. Follow-Up Studies. Humans. Instillation, Drug. Lung Neoplasms / diagnostic imaging. Lung Neoplasms / drug therapy. Male. Middle Aged. Pericardium / drug effects. Stomach Neoplasms / diagnostic imaging. Stomach Neoplasms / drug therapy. Treatment Outcome

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  • [Copyright] Copyright 2003 S. Karger GmbH, Freiburg
  • (PMID = 12771521.001).
  • [ISSN] 0378-584X
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; BZ114NVM5P / Mitoxantrone
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29. Terashima T, Matsuzaki T, Kawada I, Nishida J, Tanaka Y, Morishita T, Takeyasu Y, Yamane GY, Uchiyama T: Tongue metastasis as an initial presentation of a lung cancer. Intern Med; 2004 Aug;43(8):727-30
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  • The patient received radiation therapy combined with systemic chemotherapy, however, he died 5 months after the diagnosis of lung cancer.
  • An autopsy revealed a lung cancer in the right lower lobe with metastatic tumors in the tongue, right middle lobe, left upper lobe, liver, adrenal gland, pericardium, heart, and subcutaneous tissues.
  • No other possible primary cancer that may have been the cause of the metastases was identified.
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Combined Modality Therapy. Fatal Outcome. Humans. Male. Middle Aged

  • Genetic Alliance. consumer health - Lung Cancer.
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  • (PMID = 15468975.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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30. Chapelier AR, Missana MC, Couturaud B, Fadel E, Fabre D, Mussot S, Pouillart P, Dartevelle PG: Sternal resection and reconstruction for primary malignant tumors. Ann Thorac Surg; 2004 Mar;77(3):1001-6; discussion 1006-7
MedlinePlus Health Information. consumer health - Bone Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nine patients had received preoperative chemotherapy.
  • Resection was extended to the anterior chest-wall in 4 patients, lung in 4, brachiocephalic vein in 3, superior vena cava in 2, and pericardium in 1.
  • Soft tissue coverage was done by the pectoralis major muscles with skin advancement in 25 patients, a myocutaneous flap in 11, a breast transposition in 1, and a skin flap in 1.
  • Metastases developed in eight.
  • Large sternal defects are safely reconstructed with a musculocutaneous flap.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Male. Middle Aged. Postoperative Complications. Reoperation. Thoracic Surgical Procedures / methods. Treatment Outcome

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  • (PMID = 14992915.001).
  • [ISSN] 0003-4975
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Debourdeau P, Gligorov J, Teixeira L, Aletti M, Zammit C: [Malignant cardiac tumors]. Bull Cancer; 2004 Nov;91 Suppl 3:136-46

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The presence of metastatic tumor to the heart usually indicates widespread metastases.
  • Apart from primary pericardial mesothelioma, primary cardiac tumors are high-grade sarcomas with a high metastatic potency that often becomes evident early after surgery.
  • Cardiac RMI is helpful to estimate vessels and pericardium involvement.
  • Due to its poor prognosis, treatment of cardiac metastases is restricted to best supportive care.
  • For primary cardiac neoplasms, surgery must be carefully discussed because operative intervention is often followed by rapid widespread metastases that adjuvant chemotherapy cannot avoid in most cases.

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  • (PMID = 15899620.001).
  • [ISSN] 1769-6917
  • [Journal-full-title] Bulletin du cancer
  • [ISO-abbreviation] Bull Cancer
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 53
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