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1. Tang CP, Wang YW, Shiau YT, Lee RC, Lan KH, Chao Y: Gastropericardial fistula and Candida albicans pericarditis: a rare complication of gastric adenocarcinoma treated with radiation and chemotherapy. J Chin Med Assoc; 2009 Jul;72(7):374-8
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  • [Title] Gastropericardial fistula and Candida albicans pericarditis: a rare complication of gastric adenocarcinoma treated with radiation and chemotherapy.
  • We report a 47-year-old man with gastric adenocarcinoma who had completed radiotherapy and was on scheduled chemotherapy, who presented with fever and chest pain.
  • Initial chest radiography and computed tomography (CT) revealed no evident pericardial air or fluid.
  • However, follow-up panendoscopy 2 weeks later revealed a malignant ulcer with a fistula opening over the lesser curvature of the high body of the stomach.
  • Total parenteral nutrition and antifungal therapy were administered.
  • This case demonstrates that first, panendoscopy may be safely performed in patients with gastropericardial fistula without significant risk of cardiac tamponade; second, although early diagnosis of gastropericardial fistula is generally important, delayed recognition may not lead to devastating outcomes even in the absence of surgical intervention.
  • [MeSH-major] Adenocarcinoma / complications. Candidiasis / etiology. Fistula / etiology. Gastric Fistula / etiology. Pericarditis / etiology. Pericardium. Stomach Neoplasms / complications
  • [MeSH-minor] Combined Modality Therapy. Endoscopy. Humans. Male. Middle Aged. Pneumopericardium / diagnosis. Pneumopericardium / etiology

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  • (PMID = 19581144.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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2. Geboes K, Dekker W, Mulder CJ, Nusteling K, Dutch Study Group: Long-term lansoprazole treatment for gastro-oesophageal reflux disease: clinical efficacy and influence on gastric mucosa. Aliment Pharmacol Ther; 2001 Nov;15(11):1819-26
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  • [Title] Long-term lansoprazole treatment for gastro-oesophageal reflux disease: clinical efficacy and influence on gastric mucosa.
  • The influence of long-term therapy with lansoprazole has not been examined.
  • AIM: To study the clinical and endoscopic efficacy and histological evolution of gastric mucosa during 5 years of maintenance treatment with lansoprazole, 30 mg.
  • In the Helicobacter pylori-positive group, 20 patients developed pangastritis, six had normal histology and one had antral gastritis.
  • There was no increase in intestinal metaplasia, but there was a tendency towards regression of atrophy in the antrum and towards increased atrophy in the body of the stomach.
  • CONCLUSIONS: Maintenance treatment with lansoprazole, 30 mg, is efficacious.
  • [MeSH-major] Enzyme Inhibitors / administration & dosage. Enzyme Inhibitors / pharmacology. Gastric Mucosa / drug effects. Gastric Mucosa / pathology. Gastroesophageal Reflux / drug therapy. Helicobacter Infections / complications. Omeprazole / administration & dosage. Omeprazole / analogs & derivatives. Omeprazole / pharmacology
  • [MeSH-minor] 2-Pyridinylmethylsulfinylbenzimidazoles. Aged. Drug Administration Schedule. Endoscopy. Esophagitis / drug therapy. Esophagitis / etiology. Esophagitis / pathology. Female. Follow-Up Studies. Gastritis / drug therapy. Gastritis / etiology. Gastritis / pathology. Helicobacter pylori / pathogenicity. Humans. Lansoprazole. Male. Middle Aged. Risk Factors. Stomach Neoplasms / etiology. Stomach Neoplasms / prevention & control

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  • (PMID = 11683696.001).
  • [ISSN] 0269-2813
  • [Journal-full-title] Alimentary pharmacology & therapeutics
  • [ISO-abbreviation] Aliment. Pharmacol. Ther.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / 2-Pyridinylmethylsulfinylbenzimidazoles; 0 / Enzyme Inhibitors; 0K5C5T2QPG / Lansoprazole; KG60484QX9 / Omeprazole
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3. Charfi S, Krichen-Makni S, Yaich S, Makni H, Khabir A, Amouri A, Charfeddine K, Hachicha J, Sellami-Boudawara T: Successful treatment of post-renal transplant gastric and pulmonary Kaposi's sarcoma with conversion to rapamycin treatment. Saudi J Kidney Dis Transpl; 2007 Nov;18(4):617-20
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  • [Title] Successful treatment of post-renal transplant gastric and pulmonary Kaposi's sarcoma with conversion to rapamycin treatment.
  • An upper gastrointestinal endoscopy revealed an ulcer in the body of the stomach.
  • Computed tomography of the chest revealed multiple bilateral lung micronodules.
  • This resulted in a regression of both stomach and pulmonary KS.
  • One-year later, the patient developed an episode of acute rejection, which was successfully treated with bolus steroids.
  • [MeSH-major] Immunosuppressive Agents / therapeutic use. Kidney Transplantation / adverse effects. Lung Neoplasms / drug therapy. Sarcoma, Kaposi / drug therapy. Sirolimus / therapeutic use. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Endoscopy, Gastrointestinal. Follow-Up Studies. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 17951954.001).
  • [ISSN] 1319-2442
  • [Journal-full-title] Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia
  • [ISO-abbreviation] Saudi J Kidney Dis Transpl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; W36ZG6FT64 / Sirolimus
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4. Pavlović M, Radlović N, Leković Z, Berenji K, Novak A: [Corticosteroid therapy in Henoch-Schönlein gastritis]. Srp Arh Celok Lek; 2007 Mar-Apr;135(3-4):208-11
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  • [Title] [Corticosteroid therapy in Henoch-Schönlein gastritis].
  • In most cases, HSP spontaneously resolves without treatment.
  • Upper endoscopy showed an edematous and erythematous change in the body of the stomach and purpuric lesions in the duodenum, while multiple erosions were found in the antral area.
  • Parenteral corticosteroid therapy with gastric acid secretion inhibitor administration led to regression of gastrointestinal symptoms on the seventh day, with relapses on the fourth and sixth day.
  • CONCLUSION: Corticosteroid therapy with gastric acid secretion inhibitors showed a positive effect in our patient with a severe form of HSP accompanied by abdominal pain and gastrointestinal hemorrhage.
  • [MeSH-major] Gastritis / drug therapy. Glucocorticoids / therapeutic use. Methylprednisolone / therapeutic use. Purpura, Schoenlein-Henoch / drug therapy

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  • (PMID = 17642464.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
  • [Chemical-registry-number] 0 / Glucocorticoids; X4W7ZR7023 / Methylprednisolone
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5. Yoshino S, Nakamura S, Matsumoto T, Konomi H, Hirahashi M, Yao T, Iida M: [A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy]. Nihon Shokakibyo Gakkai Zasshi; 2006 Feb;103(2):162-7
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  • [Title] [A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy].
  • A 77-year-old man was admitted to our hospital with complaints of abdominal pain and body weight loss.
  • Esophagogastroduodenoscopy on admission revealed large ulcerative tumor in the entire region from upper to lower body of the stomach.
  • We diagnosed gastric malignant lymphoma, diffuse large B-cell type and determined stage IV according to the Lugano International Conference classification.
  • Due to gastric perforation occurred on day 4 of chemotherapy, total gastrectomy and partial resection of the transverse colon were performed.
  • Complete remission was achieved by 2 cycles of postoperative chemotherapy together with rituximab.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Lymphoma, B-Cell / complications. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / complications. Lymphoma, Large B-Cell, Diffuse / drug therapy. Stomach Diseases / chemically induced. Stomach Neoplasms / complications. Stomach Neoplasms / drug therapy

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  • (PMID = 16506664.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VEP-THP protocol
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6. Nakamura Y, Otani S, Otaka M, Shimada T, Takahashi S, Saito M, Takahashi T, Komatsu M, Suzuki T, Okubo S, Hayashi M, Sasano H: Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy. Int J Clin Oncol; 2005 Oct;10(5):348-52
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  • [Title] Gastric small cell carcinoma with marked response to neoadjuvant chemotherapy.
  • We report a patient with gastric small cell carcinoma (SCC) who showed a marked response to neoadjuvant chemotherapy.
  • Subsequent examination revealed the presence of advanced gastric carcinoma in the lesser curvature of the lower body of the stomach, with multiple abdominal lymph node metastases.
  • Endoscopic biopsy specimens from the tumor revealed SCC with moderately differentiated adenocarcinoma.
  • The patient received neoadjuvant chemotherapy consisting of carboplatin (400 mg/m2, for 1 day), epirubicin (27 mg/m2, for 1 day), etoposide (70 mg/m2, for 3 days), and 5-fluorouracil (330 mg/m2, for 11 days).
  • Clinically, the primary tumor and lymph node metastases were markedly reduced.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Small Cell / drug therapy. Neoadjuvant Therapy. Stomach Neoplasms / drug therapy

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  • (PMID = 16247663.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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7. Kusaba H, Fujihara M, Nagashima R, Kaji Y, Baba E, Nakano S: Systemic chemotherapy of TS-1 and cisplatin for gastric signet-ring cell carcinoma presenting as cardiac tamponade. Med Oncol; 2008;25(2):241-4
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  • [Title] Systemic chemotherapy of TS-1 and cisplatin for gastric signet-ring cell carcinoma presenting as cardiac tamponade.
  • An endoscopic study revealed gastric cancer in the lesser curvature wall of the middle body of the stomach, and signet-ring cell carcinoma was confirmed histologically.
  • The gastric cancer was complicated by malignant pericardial effusion, and metastasis to the mediastinal lymph nodes.
  • The patient was treated with pericardiocentesis followed by systemic chemotherapy consisting of TS-1 and cisplatin (CDDP).
  • After 5 months, pericardial effusion disappeared and the primary gastric tumor decreased in size.
  • Our experience suggests that the systemic chemotherapy of TS-1 and CDDP may be effective for controlling advanced gastric signet-cell carcinoma accompanied by malignant pericardial effusion.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Signet Ring Cell / drug therapy. Cardiac Tamponade / etiology. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Cisplatin / administration & dosage. Drug Combinations. Humans. Male. Middle Aged. Oxonic Acid / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 18488163.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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8. Centanni M, Gargano L, Canettieri G, Viceconti N, Franchi A, Delle Fave G, Annibale B: Thyroxine in goiter, Helicobacter pylori infection, and chronic gastritis. N Engl J Med; 2006 Apr 27;354(17):1787-95
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  • BACKGROUND: Malabsorption of thyroxine has been described in patients treated with drugs that modify an acidic environment.
  • Of these 248 patients, 53 also had Helicobacter pylori-related gastritis and 60 had atrophic gastritis of the body of the stomach (31 with evidence of H. pylori infection and 29 without such evidence).
  • In addition, variation in the level of serum thyrotropin was prospectively studied in 11 patients treated with thyroxine before and after H. pylori infection and both before and during treatment with omeprazole in 10 patients treated with thyroxine who had gastroesophageal reflux.
  • In a similar way, omeprazole treatment was associated with an increase in the level of serum thyrotropin in all 10 patients treated with thyroxine, an effect that was reversed by an increase in the thyroxine dose by 37 percent.
  • [MeSH-major] Anti-Ulcer Agents / pharmacology. Gastritis / complications. Goiter / drug therapy. Helicobacter Infections / complications. Helicobacter pylori. Omeprazole / pharmacology. Thyrotropin / blood. Thyroxine / administration & dosage
  • [MeSH-minor] Adult. Aged. Chronic Disease. Gastric Acid / secretion. Humans. Intestinal Absorption / drug effects. Middle Aged. Prospective Studies


9. Yanagisawa S, Tsuchiya S, Kaiho T, Togawa A, Shinmura K, Okamoto R, Nishimura M, Nomura S, Nobumoto D, Miyazaki M: [Histological complete response in a case of primary squamous cell carcinoma of the stomach treated by chemotherapy with docetaxel and cisplatin plus 5-fluorouracil]. Gan To Kagaku Ryoho; 2010 Feb;37(2):307-10
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  • [Title] [Histological complete response in a case of primary squamous cell carcinoma of the stomach treated by chemotherapy with docetaxel and cisplatin plus 5-fluorouracil].
  • Endoscopic examination revealed a type 2 advanced tumor in the mid body and an elevated lesion in the upper body of the stomach.
  • Biopsy specimens from both lesions were diagnosed histologically as squamous cell carcinoma.
  • DCF combination therapy (docetaxel 75 mg/m2 day 1, CDDP 75 mg/m2 day 1, 5-FU 750 mg/m2 day 1-5) was administered.
  • After 3 courses of chemotherapy, endoscopic examination and abdominal CT findings showed remarkable reduction of the primary tumor and the lymph node metastasis, indicating a partial response (PR) to the chemotherapy.
  • This case suggested that DCF combination chemotherapy may prove useful to treat patients with advanced squamous cell carcinoma of the stomach.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Squamous Cell / drug therapy. Cisplatin / therapeutic use. Fluorouracil / therapeutic use. Stomach Neoplasms / drug therapy. Taxoids / therapeutic use
  • [MeSH-minor] Aged. Biopsy. Combined Modality Therapy. Endoscopy, Gastrointestinal. Humans. Male

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  • (PMID = 20154491.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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10. Yajima H, Kusuyama A, Fujita T, Nagayama A, Anazawa S, Yanaga K: [A case of gastric cancer with abdominal paraaortic lymph node metastases responding to TS-1 plus CDDP neoadjuvant chemotherapy]. Gan To Kagaku Ryoho; 2004 Oct;31(10):1583-5
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  • [Title] [A case of gastric cancer with abdominal paraaortic lymph node metastases responding to TS-1 plus CDDP neoadjuvant chemotherapy].
  • An endoscopic examination revealed type 3 cancer in the lower body of the stomach, and abdominal CT scan demonstrated enlarged abdominal paraaortic lymph nodes.
  • The preoperative diagnosis was cStage IV gastric cancer (cT3, cN3, cH0, cP0, cM0).
  • Since a curative operation was deemed impossible, we started neoadjuvant chemotherapy using TS1 plus cisplatin (CDDP) for downstaging.
  • TS-1 (100 mg/day) was orally administered for 3 weeks, and CDDP (90 mg/body) was administered intravenously on day 8.
  • After two courses of chemotherapy, the primary lesion was reduced in size, and the paraaortic lymph nodes disappeared on abdominal CT scan.
  • The serum tumor marker became normal.
  • The histological changes by neoadjuvant chemotherapy were judged to be grade 2 for the main tumor.
  • It is suggested that neoadjuvant chemotherapy using TS-1 plus CDDP is effective for advanced gastric cancer with massive lymph node metastases.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymph Nodes / pathology. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Aorta, Abdominal. Cisplatin / administration & dosage. Drug Administration Schedule. Drug Combinations. Female. Humans. Infusions, Intravenous. Lymphatic Metastasis. Middle Aged. Oxonic Acid / administration & dosage. Pyridines / administration & dosage. Remission Induction. Tegafur / administration & dosage

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  • (PMID = 15508455.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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11. Nomura M, Inoue Y, Fujita S, Sakao J, Hirota M, Souda S: [A case of gastric adenosquamous carcinoma with abdominal paraaortic lymph node metastases successfully treated by TS-1 plus CDDP neoadjuvant chemotherapy]. Gan To Kagaku Ryoho; 2006 Jan;33(1):99-103
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  • [Title] [A case of gastric adenosquamous carcinoma with abdominal paraaortic lymph node metastases successfully treated by TS-1 plus CDDP neoadjuvant chemotherapy].
  • An endoscopic examination revealed type 2 cancer from the upper body of the stomach to the antrum, and abdominal CT scan demonstrated enlarged abdominal paraaortic lymph nodes.
  • The preoperative diagnosis was cStage IV gastric cancer (cT 3, cN 3, cH 0, cP 0, cM 0).
  • Since a curative operation was deemed impossible, we conducted neoadjuvant chemotherapy using TS-1 plus cisplatin (CDDP) for downstaging.
  • After two courses of chemotherapy the primary lesion and the paraaortic lymph nodes were significantly reduced in size.
  • She was judged as clinical PR, followed by distal gastrectomy and lymph node dissection, resulting in curability A.
  • Histopathologically, the tumor was diagnosed as adenosquamous carcinoma of the stomach with lymph node metastasis at only No.3.
  • This case suggests that neoadjuvant chemotherapy using TS-1 plus CDDP is effective for advanced gastric adenosquamous carcinoma with massive lymph node metastases.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Adenosquamous / drug therapy. Carcinoma, Adenosquamous / secondary. Lymph Nodes / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aorta, Abdominal. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Drug Administration Schedule. Drug Combinations. Female. Gastrectomy. Humans. Lymphatic Metastasis. Middle Aged. Neoadjuvant Therapy. Oxonic Acid / administration & dosage. Preoperative Care. Pyridines / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 16410707.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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12. Kojima Y, Kii T, Takiuchi H, Kuwakado S, Kawabe S, Gotoh M, Yoshida M, Higuchi K, Egashira Y, Tanigawa N: [A resected case of effective treatment with S-1+CPT-11 combination chemotherapy for advanced gastric cancer]. Gan To Kagaku Ryoho; 2010 Jul;37(7):1381-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A resected case of effective treatment with S-1+CPT-11 combination chemotherapy for advanced gastric cancer].
  • We report a resected case of effective treatment with S-1+CPT-11 combination chemotherapy for advanced gastric cancer.
  • The patient was a 65-year-old man who had a type 3 gastric cancer from the middle body of the stomach to the angle.
  • An abdominal CT scan demonstrated bulky lymph node metastasis (cType 3, T3, N2, M0, cStage IIIb), which was then treated with S-1+CPT-11 (S-1 80 mg/m2 day 1-21, CPT-11 80 mg/m2 day 1, 15/5 weeksx2 courses)as neoadjuvant chemotherapy.
  • After 2 courses of chemotherapy, the primary lesion and regional metastatic lymph nodes were reduced by CT (cType 3, T2, N2, M0, cStage IIIa).
  • The histological diagnosis was pT2 (ss), pN0, sH0, pCY0, sP0, sM0, tub2, INF beta, ly0, v1, n0, stage I b, Cur A, and the histological effect of the main tumor was judged to be Grade 1b.
  • This case suggests that neoadjuvant chemotherapy with S-1+CPT-11 is a potential regimen for advanced gastric cancer.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Camptothecin / analogs & derivatives. Neoadjuvant Therapy. Oxonic Acid / therapeutic use. Stomach Neoplasms / drug therapy. Stomach Neoplasms / surgery. Tegafur / therapeutic use
  • [MeSH-minor] Aged. Drug Combinations. Gastrectomy. Gastroscopy. Humans. Male. Neoplasm Staging. Remission Induction. Tomography, X-Ray Computed

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  • (PMID = 20647732.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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13. Kubo N, Nobuhara Y, Kanemura M, Sunami T, Nishimura S, Ako E, Yo T: [A case of cytology-positive, stage IV gastric cancer, alive with no recurrence for 4 years, curatively treated with combination chemotherapy using S-1, CPT-11 and subsequent total gastrectomy]. Gan To Kagaku Ryoho; 2007 Nov;34(11):1865-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of cytology-positive, stage IV gastric cancer, alive with no recurrence for 4 years, curatively treated with combination chemotherapy using S-1, CPT-11 and subsequent total gastrectomy].
  • Endoscopic examination revealed type 4 advanced gastric cancer at the upper body of the stomach.
  • In February, 2003, he patient had probe laparotomy because there was a small amount of ascites in his peritoneal cavity, and intraoperative washing cytology revealed cancer cells in ascites.Subsequently, we started chemotherapy using S-1 and CPT-11.
  • S-1 at a dose of 100 mg/day was orally administered for 2 weeks, and CPT-11 at a dose of 90 mg/body was intravenously administered once a week for 2 weeks followed by a 2-week drug-free period as 1 course.
  • After 7 courses of the chemotherapy, the main lesion endoscopically vanished.Subsequently, the patient underwent curative total gastrectomy together with D2 lymph node dissection.
  • This therapy induced Grade 2 effect on cancer cells.Postoperatively, only S-1 was administered to the patient, who has remained alive with no recurrence for 4 years as of January, 2007.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / surgery. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Ascitic Fluid / pathology. Gastrectomy. Stomach Neoplasms / drug therapy. Stomach Neoplasms / surgery
  • [MeSH-minor] Aged. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Drug Administration Schedule. Drug Combinations. Humans. Lymph Node Excision. Male. Neoplasm Staging. Oxonic Acid / administration & dosage. Remission Induction. Tegafur / administration & dosage

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  • (PMID = 18030026.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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14. Tsushima T, Tsuji Y, Abe S, Tamura F, Mizushima T, Nagashima H, Oura K, Kukitsu T, Sumiyoshi T, Yoshizaki N, Kondo H: [A case of metastatic gastric endocrine cell carcinoma which could be curably resected after chemotherapy with S-1/CDDP]. Gan To Kagaku Ryoho; 2008 May;35(5):817-20
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of metastatic gastric endocrine cell carcinoma which could be curably resected after chemotherapy with S-1/CDDP].
  • Gastric endocrine cell carcinoma is known to be highly malignant with a poor prognosis, and no standard treatment has been established.
  • We experienced a case of endocrine cell carcinoma of the stomach with liver and lymph node metastases.
  • The lesions became resectable at curability B after chemotherapy with S-1/cisplatin (CDDP).
  • A 30-mm tumor was found at the greater curvature of the lower body of the stomach, and was histologically diagnosed as an endocrine cell carcinoma from the biopsy specimen.
  • A computed tomography (CT) scan and abdominal magnetic resonance imaging (MRI) showed masses at S5 and S6 of the liver, and No. 4 lymph node enlargement.
  • Diagnosed as gastric endocrine cell carcinoma with liver and lymph node metastases, he was referred to our hospital.
  • We started chemotherapy with a daily dose of S-1 administered on days 1 to 14 and CDDP of 70 mg/m(2) on day 8, every 4 weeks.
  • After three courses of treatment, the primary lesion became a small scar and the metastatic lesions vanished from the CT and MRI.
  • Then we performed distal gastrectomy with lymph node dissection and partial liver resectomy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Small Cell / therapy. Stomach Neoplasms / therapy
  • [MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Cisplatin / administration & dosage. Drug Combinations. Gastrectomy. Humans. Liver Neoplasms / secondary. Lymphatic Metastasis. Magnetic Resonance Imaging. Male. Middle Aged. Oxonic Acid / administration & dosage. Tegafur / administration & dosage. Tomography, X-Ray Computed

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  • (PMID = 18487920.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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15. Kinoshita K, Kondo K, Watanabe K: [A case of advanced gastric cancer with distant lymph node metastases in cervical, supraclavicular and superior mediastinum successfully treated with S-1/Cisplatin (CDDP)/Lentinan combination chemotherapy]. Gan To Kagaku Ryoho; 2010 Apr;37(4):707-10
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of advanced gastric cancer with distant lymph node metastases in cervical, supraclavicular and superior mediastinum successfully treated with S-1/Cisplatin (CDDP)/Lentinan combination chemotherapy].
  • The patient was a 76-year-old Japanese woman suffering from a left cervical tumor.
  • An endoscopic examination revealed type 3 gastric cancer in the middle body of the stomach.
  • Histopathological study showed poorly-differentiated adenocarcinoma in both stomach and supraclavicular lymph node.
  • Since a curative operation was deemed impossible, S-1(100 mg/body) was administered orally for 21 consecutive days with a 14-day interval as one course combined with intravenous Lentinan (2 mg/body) once a week.
  • However, gastric endoscopic biopsy still showed a remnant malignant lesion.
  • After 5 courses of the chemotherapy, both the primary lesion and the distant lymph node swelling disappeared on gastroscopy and PET-CT, respectively, which was a so-called complete response(CR).
  • After that, only S-1 was administered for 3 weeks followed by a drug-free week as a course.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cisplatin / therapeutic use. Head / pathology. Lentinan / therapeutic use. Neck / pathology. Oxonic Acid / therapeutic use. Stomach Neoplasms / drug therapy. Tegafur / therapeutic use
  • [MeSH-minor] Aged. Drug Combinations. Female. Gastroscopy. Humans. Lymphatic Metastasis. Neoplasm Staging. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • (PMID = 20414031.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 37339-90-5 / Lentinan; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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16. Nagaie T, Morita M, Nakagawa M, Itoh S, Aikawa M, Yagi S, Wakiyama S, Kitte T, Shimotakahara A, Kawaguchi A, Wada H, Nakanishi K, Kihara K, Koyanagi N: [A remarkably improved multimetastatic gastric cancer with the use of TS-1 and CDDP]. Gan To Kagaku Ryoho; 2001 Dec;28(13):2069-72
Hazardous Substances Data Bank. CIS-DIAMINEDICHLOROPLATINUM .

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  • On the abdominal ultrasound and abdominal CT, there was evidence of multiple, massive liver metastases with dilatation of intrahepatic bile ducts, thickened wall of the stomach from the body to the antrum, direct invasion to the pancreas, multiple lymph node metastases, and ascites.
  • On the follow-up CT and ultrasound three months later, the thickening of the gastric wall and the lymph node metastasis had improved and the border between the stomach and the pancreas had become clearer.
  • No side effects were evident during the treatment with the medications.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Cisplatin / administration & dosage. Drug Administration Schedule. Drug Combinations. Humans. Male. Middle Aged. Oxonic Acid / administration & dosage. Pyridines / administration & dosage. Quality of Life. Tegafur / administration & dosage

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  • (PMID = 11791387.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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17. Moschovi M, Menegas D, Stefanaki K, Constantinidou CV, Tzortzatou-Stathopoulou F: Primary gastric Burkitt lymphoma in childhood: associated with Helicobacter pylori? Med Pediatr Oncol; 2003 Nov;41(5):444-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PROCEDURE: We reviewed and analyzed the charts of 135 patients with NHL that were diagnosed and treated in a single oncology unit during the last 20 years.
  • Upper gastroduodenal endoscopy detected an ulcer in the lesser curvature of the body of the stomach, in both cases.
  • The two patients received chemotherapy for 6 months.
  • Additionally, one of the two patients received a triple therapy regimen with bismuth, amoxicillin, and metronidazole for H. pylori.
  • [MeSH-major] Burkitt Lymphoma / epidemiology. Burkitt Lymphoma / pathology. Helicobacter Infections / epidemiology. Helicobacter pylori / isolation & purification. Stomach Neoplasms / epidemiology. Stomach Neoplasms / pathology

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  • [Copyright] Copyright 2003 Wiley-Liss, Inc.
  • (PMID = 14515383.001).
  • [ISSN] 0098-1532
  • [Journal-full-title] Medical and pediatric oncology
  • [ISO-abbreviation] Med. Pediatr. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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18. Matsutani T, Onda M, Miyashita M, Hao K, Yokoyama S, Matsuda T, Futami R, Takubo K, Sasajima K: Liver abscesses associated with stromal tumour of the stomach in a young woman. Eur J Gastroenterol Hepatol; 2001 Dec;13(12):1485-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver abscesses associated with stromal tumour of the stomach in a young woman.
  • She was found to have liver abscesses and a gastric submucosal mass by computed tomography and ultrasonography.
  • Gastroscopy and a barium swallow revealed a round submucosal mass with a giant ulceration in the body of the stomach.
  • The tumour was diagnosed as a stromal tumour of the stomach (leiomyosarcoma) in the final histological report.
  • The patient was discharged on postoperative day 17 without receiving adjuvant radio-chemotherapy.
  • This is a rare case of a liver abscess associated with a stromal tumour of the stomach in a young patient.
  • [MeSH-major] Leiomyosarcoma / complications. Liver Abscess / complications. Liver Abscess / microbiology. Stomach Neoplasms / complications
  • [MeSH-minor] Adult. Candida / isolation & purification. Disease-Free Survival. Female. Humans. Micrococcus / isolation & purification. Neisseria / isolation & purification. Streptococcus pyogenes / isolation & purification. Treatment Outcome

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  • (PMID = 11742198.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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19. Das BC, Kawarada Y: Long-term survival after treatment of gastric carcinoma with liver metastases. A case report. Hepatogastroenterology; 2003 Nov-Dec;50(54):2282-4
Hazardous Substances Data Bank. DOXORUBICIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival after treatment of gastric carcinoma with liver metastases. A case report.
  • Radiographic and endoscopic studies showed a Borrmann type I gastric carcinoma on the anterior surface of the body of the stomach near the greater curvature, and a metastatic work-up demonstrated two masses in the right lobe of the liver (segment 6 and 8).
  • The preoperative diagnosis was gastric carcinoma with liver metastasis (stage IV).
  • Ligation of the right portal vein and intraoperative common hepatic artery chemotherapy (one shot) was performed to destroy any non-visible metastatic tumors in the right lobe of the liver.
  • An aneurysm of the common hepatic artery developed after another shot of chemotherapy through the celiac artery one month after the operation.
  • The patient is alive and pursuing his previous occupation with no evidence of tumor recurrence.
  • Removal of the primary and metastatic lesions with portal vein ligation and intra-arterial chemotherapy is therefore effective as an active measure to prolong the survival time of gastric carcinoma patients with metastases limited to a single lobe of the liver.
  • [MeSH-major] Adenocarcinoma / secondary. Doxorubicin / administration & dosage. Gastrectomy. Hepatectomy. Infusions, Intra-Arterial. Liver Neoplasms / secondary. Lymph Node Excision. Stomach Neoplasms / surgery. Survivors
  • [MeSH-minor] Aneurysm, Ruptured / surgery. Chemotherapy, Adjuvant. Combined Modality Therapy. Follow-Up Studies. Hepatic Artery / surgery. Humans. Jejunostomy. Ligation. Male. Middle Aged. Portal Vein / surgery. Postoperative Complications / surgery. Reoperation

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  • (PMID = 14696518.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 80168379AG / Doxorubicin
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20. Facial and limb fat loss: lipoatrophy. Proj Inf Perspect; 2003 Oct;(36):11-2
MedlinePlus Health Information. consumer health - HIV/AIDS Medicines.

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  • Since the advent of potent anti-HIV therapy there have been increasing reports of changes in body composition among people living with HIV.
  • These include increases in fat in various areas of the body (the stomach area, behind the base of the neck and/or breast enlargement) or decreases in body fat (in the face, arms, and/or legs) and changes in the way the body processes fats (called lipids).
  • [MeSH-major] Anti-HIV Agents / adverse effects. Extremities / physiopathology. Face / physiopathology. HIV Infections / drug therapy. Lipodystrophy / chemically induced

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  • (PMID = 14696569.001).
  • [ISSN] 1058-7454
  • [Journal-full-title] Project Inform perspective
  • [ISO-abbreviation] Proj Inf Perspect
  • [Language] eng
  • [Publication-type] Newspaper Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-HIV Agents
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21. Tohma T, Yamamoto Y, Seki Y, Takaishi S, Sakuma Y, Funami Y, Tobita K: Weekly paclitaxel therapy is effective for gastric adenosquamous carcinoma: a case report. Hepatogastroenterology; 2009 Mar-Apr;56(90):568-70
Hazardous Substances Data Bank. TAXOL .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Weekly paclitaxel therapy is effective for gastric adenosquamous carcinoma: a case report.
  • On endoscopy, a type 3 cancer from the lower body of the stomach to the antrum was found, and abdominal CT scan demonstrated multiple liver metastases and peritoneal dissemination.
  • A distal gastorectomy was performed.
  • On, pathological examination, a diagnosis of adenosquamous carcinoma was confirmed, and lymph node metastases around the perigastric areas were found.
  • The patient was given chemotherapy consisting of S-1 alone (120 mg/day, days 1-28 with two weeks rest).
  • After two courses of chemotherapy, his liver metastases were found to have progressed, and paclitaxel was given at a weekly dose of 80 mg/m2 for 3 weeks, followed by a one-week rest.
  • Thus, extensive chemotherapy for the liver metastases improved the patient's prognosis, while maintaining his quality of life.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Carcinoma, Adenosquamous / drug therapy. Paclitaxel / therapeutic use. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Aged. Gastroscopy. Humans. Lymphatic Metastasis. Male. Tomography, X-Ray Computed

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  • (PMID = 19579645.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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22. Bhasin DK, Sharma BC, Ray P, Pathak CM, Singh K: Comparison of seven and fourteen days of lansoprazole, clarithromycin, and amoxicillin therapy for eradication of Helicobacter pylori: a report from India. Helicobacter; 2000 Jun;5(2):84-7
Hazardous Substances Data Bank. Clarithromycin .

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  • [Title] Comparison of seven and fourteen days of lansoprazole, clarithromycin, and amoxicillin therapy for eradication of Helicobacter pylori: a report from India.
  • BACKGROUND: In developed countries, a 1-week regimen of combined proton pump inhibitors and two antibiotics is considered adequate for Helicobacter pylori eradication.
  • However, there is a paucity of reports from developing countries on treatment duration of less than 14 days.
  • Patients were randomly selected to receive lansoprazole, 30 mg once daily, plus clarithromycin, 250 mg twice daily, plus amoxicillin, 500 mg three times daily for 2 weeks (group 1; n = 24; age, 36 +/- 12 years; 18 men) or 1 week (group 2; n = 22; age, 45 +/- 15 years; 12 men).
  • One month after completion of treatment, repeat upper gastrointestinal endoscopy was performed. H. pylori eradication was defined as absence of organism on histopathological examination of both antrum and body of stomach and negative rapid urease test.
  • CONCLUSIONS: Fourteen-day therapy with lansoprazole, clarithromycin, and amoxicillin is highly effective in eradication of H. pylori.
  • Reducing duration of therapy to 7 days significantly lowers eradication rates.
  • [MeSH-major] Amoxicillin / therapeutic use. Anti-Bacterial Agents / therapeutic use. Clarithromycin / therapeutic use. Helicobacter Infections / drug therapy. Helicobacter pylori. Omeprazole / analogs & derivatives. Omeprazole / therapeutic use
  • [MeSH-minor] 2-Pyridinylmethylsulfinylbenzimidazoles. Adolescent. Adult. Aged. Drug Therapy, Combination / therapeutic use. Female. Humans. India. Lansoprazole. Male. Middle Aged. Penicillins / administration & dosage. Penicillins / therapeutic use

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  • (PMID = 10849056.001).
  • [ISSN] 1083-4389
  • [Journal-full-title] Helicobacter
  • [ISO-abbreviation] Helicobacter
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / 2-Pyridinylmethylsulfinylbenzimidazoles; 0 / Anti-Bacterial Agents; 0 / Penicillins; 0K5C5T2QPG / Lansoprazole; 804826J2HU / Amoxicillin; H1250JIK0A / Clarithromycin; KG60484QX9 / Omeprazole
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23. Kusayanagi S, Konishi K, Miyasaka N, Sasaki K, Kurahashi T, Kaneko K, Akita Y, Yoshikawa N, Kusano M, Yamochi T, Kushima M, Mitamura K: Primary small cell carcinoma of the stomach. J Gastroenterol Hepatol; 2003 Jun;18(6):743-7
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

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  • [Title] Primary small cell carcinoma of the stomach.
  • We report on an 80-year-old man with primary gastric small cell carcinoma (SmCC).
  • An upper gastrointestinal examination revealed an irregularly ulcerated tumor, 60 mm in diameter, on the lesser curvature of the stomach body extending to the cardia.
  • An endoscopic biopsy revealed a solid proliferation of intermediate-sized tumor cells with hyperchromatic nuclei and scanty cytoplasm.
  • No tumor was detected on examination of the chest.
  • In the reported cases of gastric SmCC, the endoscopic findings frequently indicated a submucosal tumor.
  • Most patients with gastric SmCC die within 1 year of diagnosis.
  • Although a standard treatment for gastric SmCC has not been established, intensive chemotherapy should be considered to promote long-term survival.
  • We believe that careful examination, including immunohistochemical investigation, is necessary for determining the therapeutic strategy whenever gastric SmCC is suspected during endoscopy.
  • [MeSH-major] Carcinoma, Small Cell / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor. Biopsy. Carcinoembryonic Antigen. Chromogranin A. Chromogranins. Endoscopy, Gastrointestinal. Gastric Mucosa / pathology. Humans. Immunohistochemistry. Male. Phosphopyruvate Hydratase

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  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 12753162.001).
  • [ISSN] 0815-9319
  • [Journal-full-title] Journal of gastroenterology and hepatology
  • [ISO-abbreviation] J. Gastroenterol. Hepatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Chromogranin A; 0 / Chromogranins; EC 4.2.1.11 / Phosphopyruvate Hydratase
  • [Number-of-references] 27
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24. Al-Daraji WI, Al-Mahmoud RM, Ilyas M: Gastric changes following colchicine therapy in patients with FMF. Dig Dis Sci; 2008 Aug;53(8):2079-82
Hazardous Substances Data Bank. COLCHICINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric changes following colchicine therapy in patients with FMF.
  • Colchicine is highly effective in the treatment of FMF and in preventing the development of recurrent attacks and amyloidosis, and it is essential to make the correct diagnosis and institute daily therapy with colchicine (0.5-0.6 mg bid).
  • This included biopsies from stomach body (38), stomach antrum (50), and colon (24).
  • RESULTS: Three patients known to have FMF and on colchicine therapy showed typical histological features of colchicine (metaphase mitoses, epithelial pseudoproliferation, mucin depletion, and frequent apoptosis).
  • CONCLUSION: This is the first report of histological changes seen in the stomach following colchicine therapy.
  • In contrast with previous reports, we did not find any definitive change in the large intestine.
  • [MeSH-major] Colchicine / adverse effects. Familial Mediterranean Fever / drug therapy. Stomach / drug effects
  • [MeSH-minor] Adolescent. Adult. Apoptosis / drug effects. Colon / drug effects. Egypt. Female. Gastric Mucosa / drug effects. Humans. Male. Middle Aged. Mitosis / drug effects

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  • [RetractionIn] Dig Dis Sci. 2009 Dec;54(12):2772 [19789978.001]
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  • (PMID = 18080195.001).
  • [ISSN] 0163-2116
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Retracted Publication
  • [Publication-country] United States
  • [Chemical-registry-number] SML2Y3J35T / Colchicine
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25. Maksimovic S: Double tract reconstruction after total gastrectomy in patients with gastric cancer: our experience. Med Arh; 2010;64(2):116-8
MedlinePlus Health Information. consumer health - Stomach Cancer.

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  • The double tract (DT) method is the optimal reconstruction procedure aftertotal gastrectomy for patients with gastric cancer.
  • Tumor diffused in the sections of stomach in 37 cases: cardia and body in 14 cases, body and antrum in 16 cases, and in only body of stomach in 7 cases.
  • In the pathological examination, the tumors of 34 patients were diagnosed as adenocarcinoma, 2 as malignant lymphoma, and i as leiomyosarcoma.
  • CONCLUSIONS: The benefits of this method are (1) a simple procedure;.
  • [MeSH-major] Digestive System Surgical Procedures. Gastrectomy / rehabilitation. Stomach Neoplasms / surgery

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  • (PMID = 20514781.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Bosnia and Herzegovina
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26. Matsukawa Y, Aoki M, Nishinarita S, Sawada S, Horie T, Kato K, Kawamura Y, Kawamura F, Arakawa Y, Kurosaka H, Morita K, Ohtsuka E, Oribe M, Nakano M, Kitami Y: Prevalence of Helicobacter pylori in NSAID users with gastric ulcer. Rheumatology (Oxford); 2003 Aug;42(8):947-50
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Regarding the interaction of Helicobacter pylori and non-steroidal anti-inflammatory drugs (NSAIDs), we cannot accept unanimous conclusions in inducing gastric ulcer.
  • Biopsy specimens from the antrum and lower body of the stomach were prepared for the rapid urease test and pathological evaluation. Anti-H. pylori antibody was measured by enzyme-linked immunosorbent assay.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / adverse effects. Helicobacter Infections / complications. Helicobacter pylori. Stomach Ulcer / etiology
  • [MeSH-minor] Aged. Antibodies, Bacterial / blood. Arthritis, Rheumatoid / complications. Arthritis, Rheumatoid / drug therapy. Chi-Square Distribution. Female. Gastritis / complications. Gastritis / microbiology. Humans. Male. Middle Aged

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  • (PMID = 12730504.001).
  • [ISSN] 1462-0324
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 0 / Antibodies, Bacterial
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27. Tsukioka Y, Matsumura Y, Hamaguchi T, Goto M, Muro K, Yamada Y, Shirao K: Complete response achieved following administration of S-1 in a patient with adrenal gland metastasis of 5-FU-resistant gastric cancer: a case report. Jpn J Clin Oncol; 2001 Sep;31(9):450-3
Hazardous Substances Data Bank. FLUOROURACIL .

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  • A 62-year -old male patient who had undergone total extirpation of type 3 cancer of the greater curvature of the upper stomach body at another hospital received postoperative chemotherapy with 5-FU and methotrexate.
  • About 1 year later, a 4 cm tumor of the left adrenal gland was revealed by abdominal CT and diagnosed as gastric cancer metastasizing to the adrenal gland.
  • The patient was referred to our hospital for close examination and treatment and admitted.
  • After his informed consent had been obtained, the patient received one course (4-week administration and 2-week withdrawal) of S-1 at 50 mg/body x 2/day.
  • Abdominal computed tomography performed after the end of the one course revealed that the tumor had become undetectable.
  • CR has continued to be maintained to the present time, even after seven courses.
  • We consider that the efficacy of S-1 for treatment of 5-FU-resistant gastric cancer should be verified.
  • [MeSH-major] Adrenal Gland Neoplasms / drug therapy. Adrenal Gland Neoplasms / secondary. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Resistance, Neoplasm. Stomach Neoplasms / drug therapy. Stomach Neoplasms / pathology
  • [MeSH-minor] Combined Modality Therapy. Drug Administration Schedule. Drug Combinations. Fluorouracil / pharmacology. Humans. Male. Middle Aged. Oxonic Acid / administration & dosage. Pyridines / administration & dosage. Remission Induction. Tegafur / administration & dosage

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  • (PMID = 11689601.001).
  • [ISSN] 0368-2811
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; U3P01618RT / Fluorouracil
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28. Isakov VA, Maev IV, Simanenkov VI, Kononov AV, Abdulkhakov RA, Zakharova NV, Livzan MA, Predvechnaia IK: [Results of an open multicenter study of the efficiency of one-week anti-helicobacter therapy using omeprazole, clarithromycin, and amoxicillin in patients with duodenal peptic ulcer]. Ter Arkh; 2003;75(11):71-3
Hazardous Substances Data Bank. Clarithromycin .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Results of an open multicenter study of the efficiency of one-week anti-helicobacter therapy using omeprazole, clarithromycin, and amoxicillin in patients with duodenal peptic ulcer].
  • AIM: To study the efficiency of one-week antihelicobacter therapy using omeprazole, clarithromycin, and amoxycillin in patients with duodenal peptic ulcer during its recurrence.
  • MATERIALS AND METHODS: 105 patients with recurrent peptic ulcer and a not less than 0.5-cm ulcer in the duodenal bulb was given triple therapy: omeprazole, 20 mg twice daily, amoxycillin, 1000 mg twice daily, and clarithromycin, 500 mg twice daily for 7 days.
  • Then the patients were allowed to take antacids if they were required to abolish the symptoms of recurrent peptic ulcer. H. pylori was detected in the mucosal biopsy specimens taken from the anthral part and body of the stomach at gastroduodenascopy, by using the rapid urease test and histology.
  • Gastroduodenoscopy was performed before and 4-6 weeks after the triple therapy.
  • RESULTS: The major symptoms of recurrent peptic ulcer were eliminated in 90% of the patients by the end of a course of therapy, i.e. on its day 7.
  • By the control time, the rate of ulcer cicatrization was 99.05% (104/105).
  • The coincidence of results of the two tests has indicated that H. pylori eradication was 81.9% (86/105) 4-6 weeks after termination of treatment.
  • Adverse reactions during therapy were observed in 20% of the patients; however, treatment had to be discontinued only in 2.9% of the patients.
  • CONCLUSION: One-week triple therapy using omeprazole, clarithromycin, and amoxycillin in highly effective in treating duodenal peptic ulcer during its recurrence.
  • [MeSH-major] Anti-Bacterial Agents / therapeutic use. Anti-Ulcer Agents / therapeutic use. Duodenal Ulcer / drug therapy. Helicobacter Infections / drug therapy. Helicobacter pylori / drug effects
  • [MeSH-minor] Adolescent. Adult. Aged. Amoxicillin / administration & dosage. Amoxicillin / therapeutic use. Clarithromycin / administration & dosage. Clarithromycin / therapeutic use. Drug Administration Schedule. Drug Therapy, Combination. Female. Humans. Male. Middle Aged. Omeprazole / administration & dosage. Omeprazole / therapeutic use. Russia. Treatment Outcome

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  • (PMID = 14708448.001).
  • [ISSN] 0040-3660
  • [Journal-full-title] Terapevticheskiĭ arkhiv
  • [ISO-abbreviation] Ter. Arkh.
  • [Language] rus
  • [Publication-type] Clinical Trial; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] Russia
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Anti-Ulcer Agents; 804826J2HU / Amoxicillin; H1250JIK0A / Clarithromycin; KG60484QX9 / Omeprazole
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29. Crone J, Granditsch G, Huber WD, Binder C, Innerhofer A, Amann G, Hirschl AM: Helicobacter pylori in children and adolescents: increase of primary clarithromycin resistance, 1997-2000. J Pediatr Gastroenterol Nutr; 2003 Mar;36(3):368-71
Hazardous Substances Data Bank. Clarithromycin .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Biopsies from the antrum and body of the stomach were tested by histology, urease test, and culture. H. pylori was isolated using standard culture techniques, and susceptibility to amoxicillin, clarithromycin, and metronidazole was tested using the E-test (AB-Biodisk, Sweden).
  • Resistance to clarithromycin of H. pylori may also become a future problem for the treatment of adults.
  • [MeSH-major] Anti-Bacterial Agents / pharmacology. Clarithromycin / pharmacology. Gastritis / drug therapy. Helicobacter Infections / drug therapy. Helicobacter pylori / drug effects
  • [MeSH-minor] Adolescent. Amoxicillin / pharmacology. Amoxicillin / therapeutic use. Child. Child, Preschool. Drug Resistance, Bacterial. Drug Therapy, Combination. Duodenitis / epidemiology. Duodenitis / microbiology. Female. Humans. Male. Metronidazole / pharmacology. Metronidazole / therapeutic use. Microbial Sensitivity Tests

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  • [CommentIn] J Pediatr Gastroenterol Nutr. 2003 Mar;36(3):311-3 [12604967.001]
  • (PMID = 12604976.001).
  • [ISSN] 0277-2116
  • [Journal-full-title] Journal of pediatric gastroenterology and nutrition
  • [ISO-abbreviation] J. Pediatr. Gastroenterol. Nutr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 140QMO216E / Metronidazole; 804826J2HU / Amoxicillin; H1250JIK0A / Clarithromycin
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30. Shiroko J, Goto N, Yoshimura K, Oonishi T, Nakai M, Asano H, Ukita M, Tanabashi S, Kametani M: [Effective use of TS-1 in a case of advanced gastric cancer, both in treating the tumor and in maintaining the patient's quality of life]. Gan To Kagaku Ryoho; 2002 Oct;29(10):1829-33
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Effective use of TS-1 in a case of advanced gastric cancer, both in treating the tumor and in maintaining the patient's quality of life].
  • Endoscopic examination revealed stenosis from the fornix to the body of the stomach.
  • An abdominal CT scan showed the lesion was a single mass in the stomach and swollen lymph nodes at the fornix, and revealed slight ascites and left hydronephrosis.
  • No adverse effect was seen after 3 courses of treatment, and the lesion was reduced so that it was only found in the fornix.
  • During the 1 year and 3 months of treatment with TS-1, this patient worked as mountain guide in the Hida area and was able to travel to the Himalayas in Nepal for the New Year of 2001.
  • To preserve the quality of life of cancer patients, it is worth considering outpatient treatment with TS-1.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / therapeutic use. Oxonic Acid / therapeutic use. Pyridines / therapeutic use. Quality of Life. Stomach Neoplasms / drug therapy. Tegafur / therapeutic use
  • [MeSH-minor] Drug Administration Schedule. Drug Combinations. Humans. Male. Middle Aged

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  • (PMID = 12402438.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid
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31. Kitajima M, Satoh G, Marusasa T, Konishi N, Watanabe T, Ochiai T, Nishimura K, Futagawa S: [A case of gastric cancer with peritoneal dissemination-efficacy of combination therapy with S-1 and docetaxel]. Gan To Kagaku Ryoho; 2009 Sep;36(9):1545-8
Hazardous Substances Data Bank. DOCETAXEL .

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  • [Title] [A case of gastric cancer with peritoneal dissemination-efficacy of combination therapy with S-1 and docetaxel].
  • The efficiency of new anti-cancer drugs such as the S-1 system was demonstrated in a controlled study comparing treatment and non-treatment groups.
  • We encountered a patient with gastric cancer demonstrating peritoneal dissemination, who was successfully treated by combination therapy using S-1 and docetaxel.
  • Upper GI endoscopy demonstrated a type 3 gastric cancer extending from the upper to lower body of the stomach.
  • Treatment with S-1 and docetaxel was started with the following regimen: daily oral administration of 80 mg/body S-1 for 14 days, followed by a 7-day rest and infusion of 40 mg/m2 docetaxel on day 1.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Antineoplastic Agents / administration & dosage. Drug Combinations. Female. Humans. Middle Aged. Oxonic Acid / administration & dosage. Peritoneal Neoplasms / drug therapy. Taxoids / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 19755830.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Drug Combinations; 0 / Taxoids; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 15H5577CQD / docetaxel; 5VT6420TIG / Oxonic Acid
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32. Mazaki T, Mado K, Manmoto J, Okame H, Ishii Y, Suzuki K, Masuda H, Takayama T: [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11]. Gan To Kagaku Ryoho; 2008 Sep;35(9):1583-6
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 combined with CPT- 11].
  • We report three cases with liver metastasis from gastric or colon cancer successfully treated with S-1 with CPT-11.
  • Case 1: A total gastrectomy was performed for a gastric cancer located in the lower to upper body of the stomach (T3 (SE), N2, H0, P0, por 2, stage III B).
  • Abdominal computed-tomography (CT) revealed a solitary liver metastasis in the S8 subsegment of the liver.
  • We treated the patient with S-1 combined with CPT-11.
  • After surgery, the patient was treated with S-1 combined with CPT-11.
  • Case 3: Laparoscopic right hemicolectomy was performed for ascending colon cancer (SE, N1, H0, P0, M0, tub 1, stage III a).
  • We treated the patient with S-1 combined with CPT-11.
  • [MeSH-major] Camptothecin / analogs & derivatives. Colonic Neoplasms / drug therapy. Colonic Neoplasms / pathology. Liver Neoplasms / secondary. Oxonic Acid / therapeutic use. Stomach Neoplasms / drug therapy. Stomach Neoplasms / pathology. Tegafur / therapeutic use
  • [MeSH-minor] Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Combinations. Female. Humans. Male. Middle Aged. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 18799916.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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33. Rallis TS, Patsikas MN, Mylonakis ME, Day MJ, Petanides TA, Papazoglou LG, Koutinas AF: Giant hypertrophic gastritis (Menetrier's-like disease) in an Old English sheepdog. J Am Anim Hosp Assoc; 2007 Mar-Apr;43(2):122-7
Hazardous Substances Data Bank. CIMETIDINE .

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  • Gastrotomy revealed the presence of giant cerebriform rugal folds arising from the fundus and body of the stomach.
  • [MeSH-major] Dog Diseases / diagnosis. Dog Diseases / drug therapy. Gastritis, Hypertrophic / veterinary
  • [MeSH-minor] Animals. Anti-Inflammatory Agents / administration & dosage. Anti-Ulcer Agents / administration & dosage. Antiemetics / administration & dosage. Butylscopolammonium Bromide / administration & dosage. Cimetidine / administration & dosage. Dogs. Gastric Mucosa / pathology. Hyperplasia / veterinary. Isotonic Solutions / administration & dosage. Male. Metoclopramide / administration & dosage. Muscarinic Antagonists / administration & dosage. Prednisolone / administration & dosage. Treatment Outcome

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  • (PMID = 17339290.001).
  • [ISSN] 1547-3317
  • [Journal-full-title] Journal of the American Animal Hospital Association
  • [ISO-abbreviation] J Am Anim Hosp Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents; 0 / Anti-Ulcer Agents; 0 / Antiemetics; 0 / Isotonic Solutions; 0 / Muscarinic Antagonists; 0 / crystalloid solutions; 2Z3E1OF81V / Butylscopolammonium Bromide; 80061L1WGD / Cimetidine; 9PHQ9Y1OLM / Prednisolone; L4YEB44I46 / Metoclopramide
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34. Zeng HW, Nie B, Ge Y, Wang H, Song XJ: [Effects of different acupuncture intensities on the therapeutic effect and the gastric electric activity in the patient of diabetic gastroparesis]. Zhongguo Zhen Jiu; 2006 Sep;26(9):644-6
MedlinePlus Health Information. consumer health - Diabetes Complications.

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  • [Title] [Effects of different acupuncture intensities on the therapeutic effect and the gastric electric activity in the patient of diabetic gastroparesis].
  • OBJECTIVE: To observe clinical therapeutic effect of different acupuncture intensities on diabetic gastroparesis and to search for the best acupuncture intensity for treatment of diabetic gastroparesis.
  • METHODS: Eighty cases were randomly divided into 4 groups, strong, moderate, weak acupuncture intensity groups and an oral hypoglycemic drug group, 20 cases in each group.
  • Two weeks of treatment constituted one course.
  • The moderate intensity acupuncture group had the best clinical therapeutic effect.
  • The principal frequency and amplitude of the stomach electrogastrogram in the gastric antrum and the stomach body significantly improved in the acupuncture groups, which was better than those in the control group (P<0.05).
  • CONCLUSION: Acupuncture has significant therapeutic effect on diabetic gastroparesis, and there is a dose-effect relation between different intensities of acupuncture and curative effects,which are correlated with the regulation of the gastric electric parameters.
  • [MeSH-major] Acupuncture Therapy. Diabetes Complications / therapy. Gastroparesis / therapy. Stomach / physiopathology

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  • (PMID = 17036484.001).
  • [ISSN] 0255-2930
  • [Journal-full-title] Zhongguo zhen jiu = Chinese acupuncture & moxibustion
  • [ISO-abbreviation] Zhongguo Zhen Jiu
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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35. Michigami S, Yada K, Morita M, Hibuse Y, Ogawa Y: [Advanced gastric cancer successfully treated by TS-1--case report]. Gan To Kagaku Ryoho; 2004 Jun;31(6):921-3
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  • A 73-year-old woman came to our hospital because of poor appetite, and careful examination revealed a Borrmann type 2 tumor on the posterior wall of the lower body of the stomach as well as enlarged para aortic-lymph nodes.
  • After one course of TS-1, the enlarged para-aortic lymph nodes were no longer seen on abdominal computed tomography (CT).
  • [MeSH-major] Adenocarcinoma / drug therapy. Antimetabolites, Antineoplastic / therapeutic use. Oxonic Acid / therapeutic use. Pyridines / therapeutic use. Stomach Neoplasms / drug therapy. Tegafur / therapeutic use
  • [MeSH-minor] Aged. Aorta, Abdominal / pathology. Combined Modality Therapy. Drug Administration Schedule. Drug Combinations. Female. Gastrectomy. Humans. Lymphatic Metastasis

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  • (PMID = 15222113.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid
  • [Number-of-references] 11
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36. Park YH, Kim WS, Kang HJ, Na II, Ryoo BY, Yang SH, Lee SS, Uhm JE, Kim K, Jung CW, Park K, Ko YH: Gastric Burkitt lymphoma is a distinct subtype that has superior outcomes to other types of Burkitt lymphoma/leukemia. Ann Hematol; 2006 May;85(5):285-90
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastric Burkitt lymphoma is a distinct subtype that has superior outcomes to other types of Burkitt lymphoma/leukemia.
  • Because of the shared molecular and genetic features, the World Health Organization classification of lymphoid diseases recognizes the lymphomatous and leukemic phases of BL as a single entity: a mature B cell neoplasm, subtype Burkitt lymphoma/Burkitt cell leukemia.
  • Because BL frequently appears in the stomach, we investigated the clinical presentation and outcome of gastric BL.
  • We discovered 21 patients with gastric BL through a survey of our NHL registry, and retrospectively analyzed the distinct features of BL, including the St Jude/Murphy staging, other extranodal involvement, morphology and immunophenotype, response to treatment, and clinical outcome.
  • The stomach body and antrum were most frequently involved.
  • All 21 patients were treated with systemic intensive chemotherapy, producing a 71% (15/21) rate of complete response (CR) to chemotherapy.
  • [MeSH-major] Burkitt Lymphoma / mortality. Stomach Neoplasms / mortality
  • [MeSH-minor] Adolescent. Adult. Aged. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Child. Disease-Free Survival. Female. Follow-Up Studies. Humans. Male. Middle Aged. Remission Induction. Retrospective Studies. Survival Rate

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  • (PMID = 16518604.001).
  • [ISSN] 0939-5555
  • [Journal-full-title] Annals of hematology
  • [ISO-abbreviation] Ann. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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37. Banani SJ, Lankarani KB, Taghavi A, Bagheri MH, Sefidbakht S, Geramizadeh B: Comparison of metoclopramide oral tablets and solution in treatment of dysmotility-like dyspepsia. Am J Health Syst Pharm; 2008 Jun 1;65(11):1057-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of metoclopramide oral tablets and solution in treatment of dysmotility-like dyspepsia.
  • Assessment was based on symptom score determined by interviews and on gastric emptying time measured by ultrasonography before and after drug consumption.
  • Two antral and stomach body biopsies were taken to evaluate infection with Helicobacter pylori and the intensity of gastritis.
  • RESULTS: Symptom score and gastric emptying time were significantly reduced in both metoclopramide groups (p < 0.05) but not in the control group.
  • The absence or presence of and intensity of gastritis or H. pylori infection had no correlation with the symptom scores or gastric emptying times.
  • CONCLUSION: Metoclopramide oral solution 2 mg t.i.d. was at least as effective as metoclopramide tablets 5 mg t.i.d. in reducing symptoms of DLD and gastric emptying time.
  • [MeSH-major] Dyspepsia / drug therapy. Gastric Emptying. Gastrointestinal Agents / administration & dosage. Metoclopramide / administration & dosage
  • [MeSH-minor] Adult. Dose-Response Relationship, Drug. Double-Blind Method. Female. Humans. Male. Prospective Studies. Solutions. Tablets

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  • (PMID = 18499880.001).
  • [ISSN] 1535-2900
  • [Journal-full-title] American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
  • [ISO-abbreviation] Am J Health Syst Pharm
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gastrointestinal Agents; 0 / Solutions; 0 / Tablets; L4YEB44I46 / Metoclopramide
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38. Kirika NV, Bodrug NI, Butorov IV, Butorov SI: [Efficacy of different schemes of anti-helicobacter therapy in duodenal ulcer]. Ter Arkh; 2004;76(2):18-22
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  • [Title] [Efficacy of different schemes of anti-helicobacter therapy in duodenal ulcer].
  • AIM: To study clinical efficacy and antihelicobacter activity of combined treatment of duodenal ulcer (DU) with famotidin (qamatel), metronidasol (trichopol) and jozamycin (walpraphen).
  • MATERIAL AND METHODS: A total of 96 patients with uncomplicated DU have been treated (mean age 42.5 +/- 1.5 years).
  • The examination included standard tests, endoscopy, pH-metry (on the treatment days 1, 15 and 28), biopsies and prints from the antral stomach and its body.
  • The sections were stained by Gimse for morphological assessment of duodenal mucosa and detection of Helicobacter pylori (HP).
  • The patients were divided into 3 groups: group 1 received monotherapy with famotidin (20 mg twice a day); group 2 received combined treatment with famotidin (40 mg/day), metronidasol (500 mg twice a day), josamycin (300 mg in 3 doses) for a week with following intake of famotidin alone (40 mg/day) for 3 weeks; group 3 received the same treatment plus clarythromycin.
  • Group 1 patients benefited from the treatment but elimination of pain and dyspeptic syndromes was longer than in groups 2 and 3 (p < 0.05).
  • Ulcer healing to treatment day 28 was observed in 71.8, 90.0 and 88.2%, respectively.
  • CONCLUSION: 1-week schemes of combined treatment with famotidin, metronidasol, josamycin or clarythromycin are highly effective in DU and their side effect rates are not very high.
  • [MeSH-major] Anti-Infective Agents / therapeutic use. Anti-Ulcer Agents / therapeutic use. Duodenal Ulcer / drug therapy. Helicobacter Infections / drug therapy
  • [MeSH-minor] Adult. Clarithromycin / administration & dosage. Clarithromycin / therapeutic use. Drug Administration Schedule. Drug Therapy, Combination. Famotidine / administration & dosage. Famotidine / therapeutic use. Female. Helicobacter pylori / drug effects. Helicobacter pylori / isolation & purification. Humans. Josamycin / administration & dosage. Josamycin / therapeutic use. Male. Metronidazole / administration & dosage. Metronidazole / therapeutic use. Treatment Outcome

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  • (PMID = 15106408.001).
  • [ISSN] 0040-3660
  • [Journal-full-title] Terapevticheskiĭ arkhiv
  • [ISO-abbreviation] Ter. Arkh.
  • [Language] rus
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Russia
  • [Chemical-registry-number] 0 / Anti-Infective Agents; 0 / Anti-Ulcer Agents; 140QMO216E / Metronidazole; 5QZO15J2Z8 / Famotidine; H1250JIK0A / Clarithromycin; HV13HFS217 / Josamycin
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39. Bang YJ, Kang WK, Kang YK, Kim HC, Jacques C, Zuber E, Daglish B, Boudraa Y, Kim WS, Heo DS, Kim NK: Docetaxel 75 mg/m(2) is active and well tolerated in patients with metastatic or recurrent gastric cancer: a phase II trial. Jpn J Clin Oncol; 2002 Jul;32(7):248-54
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  • Most showed adenocarcinomas of the gastric antrum and/or body of the stomach.
  • All showed metastases and two-thirds retained the primary tumour.
  • A total of 159 cycles (median three cycles) were administered, with mean duration of treatment 10.9 weeks.
  • [MeSH-major] Adenocarcinoma / drug therapy. Paclitaxel / analogs & derivatives. Paclitaxel / therapeutic use. Stomach Neoplasms / drug therapy. Taxoids
  • [MeSH-minor] Adult. Aged. Drug Administration Schedule. Drug Evaluation. Female. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Neutropenia / chemically induced

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  • (PMID = 12324575.001).
  • [ISSN] 0368-2811
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Clinical Trial, Phase II; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel; P88XT4IS4D / Paclitaxel
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40. Nishizawa T, Suzuki H, Masaoka T, Minegishi Y, Iwasahi E, Hibi T: Helicobacter pylori eradication restored sonic hedgehog expression in the stomach. Hepatogastroenterology; 2007 Apr-May;54(75):697-700
MedlinePlus Health Information. consumer health - Stomach Disorders.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Helicobacter pylori eradication restored sonic hedgehog expression in the stomach.
  • Biopsy specimens were taken from the greater curvature of the middle third of the stomach body.
  • [MeSH-major] Hedgehog Proteins / metabolism. Helicobacter Infections / drug therapy. Helicobacter pylori. Stomach / metabolism. Stomach Diseases / drug therapy
  • [MeSH-minor] Adult. Aged. Drug Therapy, Combination. Female. H(+)-K(+)-Exchanging ATPase / analysis. Humans. Immunohistochemistry. Male. Middle Aged

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  • (PMID = 17591044.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Hedgehog Proteins; 0 / SHH protein, human; EC 3.6.3.10 / H(+)-K(+)-Exchanging ATPase
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41. Mizokami Y, Narushima K, Shiraishi T, Otsubo T, Narasaka T, Matsuoka T: Non-Helicobacter pylori ulcer disease in rheumatoid arthritis patients receiving long-term NSAID therapy. J Gastroenterol; 2000;35 Suppl 12:38-41
MedlinePlus Health Information. consumer health - Rheumatoid Arthritis.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-Helicobacter pylori ulcer disease in rheumatoid arthritis patients receiving long-term NSAID therapy.
  • Helicobacter pylori and nonsteroidal antiinflammatory drugs (NSAIDs) are considered the major causes of peptic ulcer.
  • At the ulcer site they were seen significantly less often in the antrum than in either the angle or body of the stomach (35% vs 100%) in the NSAIDs group.
  • On the other hand, the H. pylori-positive rate for ulcers in the antrum did not differ significantly from that in the angle and body of the stomach (81.8% vs 93.8%) in the control group.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / adverse effects. Arthritis, Rheumatoid / drug therapy. Helicobacter Infections / diagnosis. Helicobacter pylori. Stomach Ulcer / chemically induced


42. Noji M, Bandoh T, Isoyama T, Nagaoka S, Fujiwara M, Takemura T: [A case of complete regression of liver metastases by treatment with Futraful supposition]. Gan To Kagaku Ryoho; 2000 Feb;27(2):285-8
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  • [Title] [A case of complete regression of liver metastases by treatment with Futraful supposition].
  • X-ray and endoscopic examination revealed a Borrmann type 3 carcinoma in the posterior wall and lesser curvature of the upper body of the stomach.
  • Multiple liver metastases were revealed by computed tomography (CT).
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / secondary. Antimetabolites, Antineoplastic / administration & dosage. Liver Neoplasms / secondary. Stomach Neoplasms / drug therapy. Stomach Neoplasms / pathology. Tegafur / administration & dosage

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  • (PMID = 10700902.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Suppositories; 1548R74NSZ / Tegafur
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43. Akesaka K, Nakanishi N, Ueda N, Moritaka T, Kitajima T, Katsuta T, Furuya K: [A case of carcinomatous lymphangitis of the lungs due to stomach cancer responding to TS-1]. Gan To Kagaku Ryoho; 2004 Feb;31(2):233-5
MedlinePlus Health Information. consumer health - Stomach Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of carcinomatous lymphangitis of the lungs due to stomach cancer responding to TS-1].
  • We report a case of carcinomatous lymphangitis of the lungs due to and stomach cancer showing remarkable response to TS-1.
  • The patient was a 51-year-old man whose chest x-ray and computed tomography (CT) revealed lymphangitis, and endoscopic examination showed stomach cancer on posterior wall of stomach body.
  • We suggest that TS-1 is an effective therapy for carcinomatous lymphangitis of the lungs due to stomach cancer.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Lymphangitis / drug therapy. Lymphangitis / etiology. Oxonic Acid / therapeutic use. Pyridines / therapeutic use. Stomach Neoplasms / complications. Tegafur / therapeutic use
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / secondary. Carcinoma, Signet Ring Cell / complications. Carcinoma, Signet Ring Cell / secondary. Drug Administration Schedule. Drug Combinations. Humans. Lung Neoplasms / secondary. Male. Middle Aged. Neoplasms, Multiple Primary

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  • (PMID = 14997758.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0 / Pyridines; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid
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