[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 18 of about 18
1. Rebhandl W, Felberbauer FX, Puig S, Paya K, Hochschorner S, Barlan M, Horcher E: Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature. J Surg Oncol; 2001 Apr;76(4):289-96
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature.
  • BACKGROUND: Solid-pseudopapillary tumor of the pancreas (SPT) is an exceptionally rare neoplasm in children.
  • It is of low malignant potential and occurs most frequently in young females.
  • PATIENTS AND METHODS: A cumulative review of the tumor's clinicopathological characteristics from the world's literature is presented.
  • Two tumors were located in the tail, one in the body and tail and one in the head of the pancreas (diameter: 7--15 cm).
  • Surgical procedures included three distal pancreatectomies and one partial duodenopancreatectomy (Whipple procedure).
  • Chemotherapy was initiated for this patient.
  • CONCLUSIONS: SPT is a rare differential diagnosis of a pancreatic mass in children.
  • It is mandatory to establish this diagnosis since complete surgical removal of the tumor even in case of metastases or local invasion offers an excellent prognosis.
  • [MeSH-major] Cystadenoma, Papillary / pathology. Pancreatic Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2001 Wiley-Liss, Inc.
  • (PMID = 11320522.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
  •  go-up   go-down


2. Makino H, Kametaka H, Yasuno K, Koyama T, Seike K: [The effectiveness of reduction surgery and gemcitabine for multiple bowel obstructions due to peritoneal dissemination of pancreatic carcinoma with liver metastasis--a case report]. Gan To Kagaku Ryoho; 2009 Nov;36(12):2416-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The effectiveness of reduction surgery and gemcitabine for multiple bowel obstructions due to peritoneal dissemination of pancreatic carcinoma with liver metastasis--a case report].
  • Computed tomography (CT) revealed pancreatic carcinoma invading to spleen with liver metastasis and peritoneal dissemination.
  • The pancreatic carcinoma was located at the tail of pancreas invading to spleen with liver metastasis.
  • We performed a distal pancreatectomy, partial hepatectomy, partial resection of the stomach, five-partial resection of the small intestine, right colectomy and sigmoidectomy.
  • No operative complication was seen, and we started chemotherapy using gemcitabine soon after the operation.
  • After 3 months, the tumor markers normalized.
  • The removal of bowel obstruction by operation enabled us to perform intestinal nutrition and sufficient chemotherapy, which may lead to the favorable prognosis.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Deoxycytidine / analogs & derivatives. Intestinal Obstruction / therapy. Liver Neoplasms / secondary. Pancreatic Neoplasms / pathology. Peritoneal Neoplasms / complications. Peritoneal Neoplasms / secondary
  • [MeSH-minor] Combined Modality Therapy. Female. Humans. Middle Aged

  • MedlinePlus Health Information. consumer health - Intestinal Obstruction.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20037441.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
  •  go-up   go-down


3. Doi M, Imai T, Shichiri M, Tateno T, Fukai N, Ozawa N, Sato R, Teramoto K, Hirata Y: Octreotide-sensitive ectopic ACTH production by islet cell carcinoma with multiple liver metastases. Endocr J; 2003 Apr;50(2):135-43
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Octreotide-sensitive ectopic ACTH production by islet cell carcinoma with multiple liver metastases.
  • We report a 21-year-old woman with ectopic ACTH syndrome due to islet cell carcinoma with multiple liver metastases.
  • She was found to have multiple masses in the liver and a solid mass in the tail of pancreas by abdominal computerized tomography scanning.
  • Treatment with octreotide successfully reduced elevated plasma ACTH and cortisol levels, and she received frequent transhepatic arterial embolization and chemotherapy.
  • The primary pancreatic tumor was surgically removed, revealing islet cell carcinoma which contained high content of ACTH (100 microg/g wet weight) and abundantly expressed proopiomelanocortin and somatostatin receptor subtype-2 mRNAs as determined by Northern blot analysis.
  • However, progressive enlargement of multiple liver metastases refractory to chemotherapy led her to decide on total hepatectomy and liver transplantation from her father.
  • However, metastases developed to the mediastinal and paraaortic lymph nodes as detected by 111[In] pentetreotide scintigraphy.
  • This case of a young female patient with ectopic ACTH-producing islet cell carcinoma of the pancreas was quite unique in that she survived for 5 years despite the acute onset and rapid progression of the multiple liver metastases at least in part due to the long-lasting favorable response to octreotide and living-related liver transplantation.
  • [MeSH-major] ACTH Syndrome, Ectopic / drug therapy. ACTH Syndrome, Ectopic / etiology. Antineoplastic Agents, Hormonal / therapeutic use. Carcinoma, Islet Cell / complications. Carcinoma, Islet Cell / secondary. Liver Neoplasms / secondary. Octreotide / therapeutic use. Pancreatic Neoplasms / complications
  • [MeSH-minor] Adult. Female. Hepatectomy. Humans. Liver Transplantation. Living Donors. Tomography, X-Ray Computed

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12803233.001).
  • [ISSN] 0918-8959
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; RWM8CCW8GP / Octreotide
  •  go-up   go-down


Advertisement
4. Schütt M, Lorch H, Krüger S, Klingenberg RD, Peters A, Klein HH: [Recurrent hypoglycemia caused by malignant insulinoma: chemoembolization as a therapeutic option]. Med Klin (Munich); 2001 Oct 15;96(10):632-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recurrent hypoglycemia caused by malignant insulinoma: chemoembolization as a therapeutic option].
  • Ultrasound and computertomography of the abdomen showed a huge inhomogeneous mass in the tail of pancreas and multiple lesions in the liver, respectively.
  • Core needle biopsies revealed typical histopathological findings of a neuroendocrine carcinoma.
  • TREATMENT AND COURSE: Eight cycles of chemotherapy were given using streptozotocin/doxorubicin for three cycles and streptozotocin/5-fluorouracil for the remaining therapy over a period of 16 months resulting in a reduction in size of liver metastases and improvement of symptoms.
  • Following 6 months without any therapy new episodes of severe hypoglycemia and progression of the liver metastases occurred.
  • Despite seven further cycles of chemotherapy and additional treatment with diazoxide/octreotide the patient remained hypoglycemic and continuous glucose infusions became necessary.
  • CONCLUSION: Chemoembolization is an effective possibility in the palliative treatment of advanced malignant insulinoma.
  • [MeSH-major] Chemoembolization, Therapeutic. Hypoglycemia / etiology. Insulinoma / therapy. Liver Neoplasms / therapy. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Diagnosis, Differential. Fatal Outcome. Female. Humans. Recurrence


5. Sheng L, Weixia Z, Longhai Y, Jinming Y: Clinical and biologic analysis of pancreatoblastoma. Pancreas; 2005 Jan;30(1):87-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Since the first description of pancreatoblastoma as a malignant pancreatic tumor of childhood in 1957, approximately 200 cases have been reported.
  • During laparotomy, a 10 x 8 x 8-cm3 tumor was discovered in the pancreatic body and tail, and with 3 cystic masses, 15, 10, and 8 cm in diameter, respectively, involving the right lobe of the liver.
  • Pathologic examination of the resected tumor revealed findings characteristic of pancreatoblastoma.
  • The tumor formed acinar and glandular structures and solid areas and contained many "squamoid corpuscles," a defining feature of pancreatoblastoma.
  • In spite of adjuvant chemotherapy with Adriamycin and gemcitabine, the patient returned 11 months later with several large hepatic masses, invading the pancreatic head and enlarged tracheobronchial lymph nodes.
  • Radiotherapy, transcatheter arterial embolization therapy, and chemotherapy were performed.
  • Unfortunately, the patient died 26 months later from disseminated tumor progression.
  • A review of the literature reveals that pancreatoblastoma in childhood must be considered malignant but usually has a favorable prognosis in contrast to pancreatic neoplasms in adult patients.
  • Biologic study will investigate the molecular biology of this rare tumor.
  • The biology may help define prognosis and therapy for this kind of tumor.
  • [MeSH-major] Pancreas / pathology. Pancreas / radiography. Pancreatic Neoplasms / pathology. Pancreatic Neoplasms / radiography

  • Genetic Alliance. consumer health - Pancreatoblastoma.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15632705.001).
  • [ISSN] 1536-4828
  • [Journal-full-title] Pancreas
  • [ISO-abbreviation] Pancreas
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


6. Yang F, Jin C, Long J, Yu XJ, Xu J, Di Y, Li J, Fu de L, Ni QX: Solid pseudopapillary tumor of the pancreas: a case series of 26 consecutive patients. Am J Surg; 2009 Aug;198(2):210-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solid pseudopapillary tumor of the pancreas: a case series of 26 consecutive patients.
  • OBJECTIVE: Solid pseudopapillary tumor (SPT) of the pancreas, which predominantly affects young women, is a relatively indolent entity with favorable prognosis.
  • Clinicopathologic factors were compared between benign and malignant cases to determine what features of the tumor could suggest malignant potential.
  • The neoplasm was localized in the pancreatic head/neck in 14 patients and in the body/tail in 12 patients.
  • All of the tumors-including 8 pancreaticoduodenectomies, 10 distal pancreatectomies, 6 local resections, 1 total pancreatectomy, and 1 central pancreatectomy-were resected successfully.
  • No patient received chemotherapy or radiotherapy after surgery.
  • One of the 2 patients with malignant SPT, in whom Ki-67 immunoreactivity was >25%, developed local recurrence with liver metastasis 4 months and died 6 months after surgery.
  • CONCLUSIONS: SPT is a rare neoplasm with low malignant potential.
  • Characteristic computed axial tomography and magnetic resonance imaging scans combined with age and sex profile should be sufficient for the decision to operate.
  • Patients with malignant SPT should have careful follow-up.
  • The high proliferative index assessed by immunohistochemical staining for Ki-67 may predict poor outcome of malignant SPT.
  • [MeSH-major] Carcinoma, Papillary / pathology. Pancreatic Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19268906.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


7. Wu G, Zhou X, Huang M: [Electrochemical therapy and implanted ports treatment for unresectable carcinoma of body and tail of pancreas]. Zhonghua Wai Ke Za Zhi; 2001 Aug;39(8):596-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Electrochemical therapy and implanted ports treatment for unresectable carcinoma of body and tail of pancreas].
  • OBJECTIVE: To examine the efficacy and safety of electrochemical therapy (ECT) in treatment of patients with unresectable carcinoma of the body and tail of pancreas.
  • METHODS: A total of 18 patients (14 men and 4 women; mean age 57.7) with unresectable carcinoma of the body and tail of pancreas were treated by ECT between May 1989 and June 1996 in our hospital (group A).
  • Another 16 patients (12 men and 4 women; mean age 60.3) were treated by ECT plus intraperitoneal chemotherapy between July 1996 and June 1999 (group B).
  • Pain was determined by using a 10-point visual analog pain scale (VAS) before and after the treatment, life quality periodically assessed according to the 5-step scale system, and tumor size measured using CT or MRI.
  • RESULTS: All the patients were followed up for 5-30 months (mean = 10 months), showing that there were no operative deaths and such complications such as pancreatic fistula and bleeding in both groups.
  • The tumor size in both groups was decreased to some degree.
  • In group A, the VAS basal score was reduced from 7.4 +/- 1.7 before to 2.66 +/- 1.05 after the treatment and the peak VAS from 9.3 +/- 0.9 to 3.71 +/- 0.96 (P < 0.05).
  • CONCLUSIONS: ECT is a safe and effective procedure for treatment of unresectable carcinoma of the body and tail of pancreas and in relieving its pain and improving the life quality of patients.
  • Supplementary injection of chemical drugs through drug delivery pump is helpful for control of ascites.
  • [MeSH-major] Electric Stimulation Therapy. Pancreatic Neoplasms / therapy

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11758195.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  •  go-up   go-down


8. Egorov AV, Kuzin NM, Kondrashin SA, Lotov AN, Kazantseva IA, Kuznetsov NS, Gurevich LE, Lakreeva MG: [Treatment of malignant pancreatic islet cell tumors]. Khirurgiia (Mosk); 2000;(5):13-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Treatment of malignant pancreatic islet cell tumors].
  • Among 142 patients with islet cell tumor who were admitted to hospital between 1982 and 1999, 15 patients (10.6%) had malignant tumours.
  • Islet cell tumors were located in the head and corpus of the pancreas in 26.6% and 26.6% of the patients, respectively, in the tail of the pancreas in 46.8% of the patients.
  • The mean size of the tumor was 2.9 +/- 0.7 cm, in 6 patients (40%) liver metastases were found.
  • US, CT and angiography which sensitivity were 72.7, 100 and 85.7%, respectively, were used for topical diagnosis of the islet cell tumors.
  • Surgical procedures included distal pancreatic resection (n = 11), enucleation of the tumor (n = 2), hepatic resection (n = 1), abdominal exploration (n = 1).
  • In 2 patients palliative pancreatic resections were combined with transarterial embolization and devascularisation of the liver metastases and 2 patients were treated by systemic chemotherapy.
  • In other cases to determine the diagnosis was possible only after planned histological identification of the resected specimens.
  • 5-year survival rates after conservative and surgical treatment were 33% and 62.5%, respectively.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Carcinoma, Islet Cell / therapy. Chemoembolization, Therapeutic. Pancreatectomy. Pancreatic Neoplasms / therapy
  • [MeSH-minor] Adult. Female. Humans. Liver Neoplasms / mortality. Liver Neoplasms / secondary. Liver Neoplasms / therapy. Male. Middle Aged. Retrospective Studies. Survival Rate. Treatment Outcome


9. Choi SH, Hwang HK, Kang CM, Lee WJ: Total pancreaticoduodenectomy and segmental resection of superior mesenteric vein-portal vein confluence with autologous splenic vein graft in mucinous cystadenocarcinoma of the pancreas. JOP; 2010;11(6):638-41
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Total pancreaticoduodenectomy and segmental resection of superior mesenteric vein-portal vein confluence with autologous splenic vein graft in mucinous cystadenocarcinoma of the pancreas.
  • CONTEXT: Mucinous cystic tumors occur almost exclusively in middle-aged women and in the body or tail of the pancreas.
  • Mucinous cystadenocarcinoma, a malignant sub-type of mucinous cystic tumors, in the head of the pancreas and in a middle-aged man is extraordinary, and the prognosis and proper management of mucinous cystadenocarcinoma has not been well documented.
  • CASE REPORT: A 52-year-old male patient with a mucinous cystadenocarcinoma approximately 5.5 cm in size in the head of the pancreas underwent a total pancreaticoduodenectomy and segmental resection of the superior mesenteric vein-portal vein confluence with an autologous splenic vein graft due to tumor invasion.
  • His postoperative course was uneventful and he received adjuvant chemotherapy.
  • CONCLUSION: Mucinous cystadenocarcinoma in the head of the pancreas in a middle-aged man is an extremely rare case.
  • [MeSH-major] Cystadenocarcinoma, Mucinous / surgery. Mesenteric Veins / surgery. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods. Portal Vein / surgery. Splenic Vein / transplantation
  • [MeSH-minor] Humans. Male. Middle Aged. Tomography, X-Ray Computed. Transplantation, Autologous

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21068503.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


10. Xie YB, Wang CF, Li CR, Shan Y, Zhao DB, Tian YT, Zhao P: [Influence of adjuvant therapy on survival of patients with pancreatic carcinoma of body and tail: a report of 137 cases]. Zhonghua Yi Xue Za Zhi; 2009 Apr 14;89(14):951-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Influence of adjuvant therapy on survival of patients with pancreatic carcinoma of body and tail: a report of 137 cases].
  • OBJECTIVE: To investigate the effect of adjuvant therapy on the treatment of carcinoma of the body and tail of pancreas.
  • METHODS: The clinical data of 137 patients with carcinoma of the body and tail of pancreas, 91 males and 46 females, aged 58.9 (24 - 76), of which 38 underwent radical resection, 24 underwent palliative resection, and 75 did not undergo resection, and 58 of which underwent adjuvant therapy, were analyzed.
  • The median survival time (MST) was 8 months for the whole group, 15 months for the radical resection group, 8 months for the palliative resection group, and 6 months for the no resection group.
  • The 3-year survival rate was 13.9% for the patients undergoing adjuvant therapy and 7.2% for those without adjuvant therapy, and the MST was 11 months for those undergoing adjuvant therapy, and 5 months for those without adjuvant therapy.
  • Intra-arterial therapy and radiation therapy were protective factors for those whose cancerous tissues were not radically resected (OR = 1.56, 95% CI: 1.04 - 2.35, P = 0.033).
  • CONCLUSION: Adjuvant therapy significantly improves the survival of the patients with pancreatic carcinoma of the body and tail.
  • The clinical effect of intra-arterial therapy is better than those of radiation therapy and chemotherapy.
  • [MeSH-major] Neoadjuvant Therapy. Pancreatic Neoplasms / drug therapy. Pancreatic Neoplasms / mortality
  • [MeSH-minor] Adult. Aged. Chemotherapy, Adjuvant. Female. Humans. Male. Middle Aged. Neoplasm Staging. Postoperative Period. Radiotherapy, Adjuvant. Retrospective Studies. Survival Rate. Treatment Outcome. Young Adult

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19671304.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  •  go-up   go-down


11. Masuda T, Kuwahara A: [A long-term survival case of unresectable malignant pancreatic endocrine tumor successfully treated with systemic chemotherapy]. Gan To Kagaku Ryoho; 2008 May;35(5):833-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A long-term survival case of unresectable malignant pancreatic endocrine tumor successfully treated with systemic chemotherapy].
  • Computed tomography showed a solid tumor in the tail of the pancreas with multiple liver tumors.
  • We diagnosed him as unresectable pancreatic tail cancer with multiple liver metastases at first, so systemic chemotherapy using UFT was performed.
  • Gradually, liver metastases were slightly reduced, and tumor markers (CEA, CA19-9) decreased to the normal range.
  • In April 2001, percutaneous transhepatic tumor biopsy was performed.
  • Histopathological examination revealed a malignant pancreatic endocrine tumor.
  • But because tumors had gradually grown since October 2003, the chemotherapy with S-1 was followed by gemcitabine (GEM).
  • The patient has now survived for 7.5 years while receiving the combined chemotherapy of S-1/GEM.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Islet Cell / drug therapy. Pancreatic Neoplasms / drug therapy
  • [MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Drug Combinations. Humans. Liver Neoplasms / secondary. Male. Middle Aged. Oxonic Acid / administration & dosage. Tegafur / administration & dosage

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18487924.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Drug Combinations; 0W860991D6 / Deoxycytidine; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; B76N6SBZ8R / gemcitabine
  •  go-up   go-down


12. Jia L, Zhang MH, Yuan SZ, Huang WG: Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice. World J Gastroenterol; 2005 Jan 21;11(3):447-50
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Antiangiogenic therapy for human pancreatic carcinoma xenografts in nude mice.
  • AIM: To investigate the anti-tumor effects of antiangiogenic therapy (a combination of TNP-470, an antiangiogenic compound, with gemcitabine, an antimetabolite) on human pancreatic carcinoma xenografts and its mechanism.
  • METHODS: A surgical orthotopic implantation (SOI) model was established by suturing small pieces of SW1990 pancreatic carcinoma into the tail of pancreas in nude male mice.
  • Mice then received either single therapy (n = 24) or combined therapy (n = 32).
  • Mice receiving single therapy were randomly divided into control group, G100 group receiving 100 mg/kg gemcitabine IP on d 0, 3, 6 and 9 after transplantation, and T30 group receiving 30 mg/kg TNP-470 s.c on alternate days for 8 wk.
  • Mice receiving combined therapy were randomly divided into control group, T15 group, G50 group and combination group (TNP-470 30 mg/kg and gemcitabine 50 mg/kg).
  • Weight of transplanted tumors, the T/C rate (the rate of mean treated tumor weight to mean control tumor weight), change of body weight, metastasis rate, and 9-wk survival rate were investigated.
  • Tumor samples were taken from the control group, T30 group, G100 group and combination group.
  • RESULTS: There was a significant inhibitory effect on primary tumor growth of pancreatic carcinoma in G100 group, compared to T30 group, whereas tumor metastasis was significantly inhibited in T30 group compared to G100 group.
  • No significant inhibitory effect on tumor growth and metastasis in T15 group and G50 group.
  • However, significant anti-tumor and anti-metastatic effects were observed in the combination group with a significant improvement in survival rate.
  • The inhibitory effect on tumor growth in combination group enhanced 2 times in comparison with G50 group and 5 times in comparison with T15 group.
  • Moreover, 25% of the animals bearing tumors were cured by the combination therapy.
  • CONCLUSION: Antiangiogenic therapy shows significant anti-tumor and anti-metastatic effects, and is helpful to reduce the dosage of cytotoxic drugs and the side effects.
  • [MeSH-major] Angiogenesis Inhibitors / pharmacology. Carcinoma / pathology. Deoxycytidine / analogs & derivatives. Pancreatic Neoplasms / pathology. Sesquiterpenes / pharmacology
  • [MeSH-minor] Animals. Antimetabolites, Antineoplastic / administration & dosage. Antimetabolites, Antineoplastic / pharmacology. Antineoplastic Combined Chemotherapy Protocols / pharmacology. Cyclohexanes. Dose-Response Relationship, Drug. Humans. Male. Mice. Mice, Inbred BALB C. Mice, Nude. Neoplasm Metastasis / prevention & control. Neoplasm Transplantation. Transplantation, Heterologous


13. Yin WH, Yu GY, Ma Y, Rao HL, Lin SX, Shao CK, Liang Q, Guo N, Chen GQ, Zhou W, Zhao T, Zhu MG: [Follicular dendritic cell sarcoma: a clinicopathologic analysis of ten cases]. Zhonghua Bing Li Xue Za Zhi; 2010 Aug;39(8):522-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: To study the clinicopathologic features of follicular dendritic cell sarcoma (FDCS) and its differential diagnosis.
  • Six of them were located in cervical and peritoneal lymph nodes and four in extranodal sites (including tonsil, pelvic cavity, tail of pancreas and spleen).
  • Histologically, the tumor cells had whorled, storiform or diffuse growth patterns.
  • Multinucleated tumor giant cells and intranuclear pseudoinclusions were occasionally seen.
  • There was a sprinkling of small lymphocytes and neutrophils within the tumor as well as in the perivascular region.
  • Immunohistochemical study showed that the tumor cells were diffusely or focally positive for CD21, CD23, CD35 and D2-40, but negative for LCA, CD20, CD3, CD1a, HMB45 and CK.
  • The remaining 5 patients were alive and disease-free after surgical excision (+/- chemotherapy and radiotherapy).
  • CONCLUSIONS: FDCS is a rare low to intermediate-grade malignant tumor.
  • Appropriate application of FDC markers, such as CD21, CD35 and D2-40, would be helpful for arriving at a correct diagnosis.
  • Most cases are associated with good prognosis after surgical treatment, with or without chemotherapy and radiotherapy.
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Murine-Derived / metabolism. Dendritic Cell Sarcoma, Interdigitating / pathology. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Lymph Node Excision. Male. Meningioma / pathology. Middle Aged. Nasopharyngeal Neoplasms / pathology. Paraneoplastic Syndromes / complications. Pemphigus / complications. Receptors, Complement 3b / metabolism. Receptors, Complement 3d / metabolism. Receptors, IgE / metabolism. Young Adult

  • Genetic Alliance. consumer health - TEN.
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21055030.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Receptors, Complement 3b; 0 / Receptors, Complement 3d; 0 / Receptors, IgE; 0 / monoclonal antibody D2-40
  •  go-up   go-down


14. Lee HY, Lee DG, Chun K, Lee S, Song SY: Clear cell carcinoma of the pancreas--a case report and review of the literature. Cancer Res Treat; 2009 Sep;41(3):175-81
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clear cell carcinoma of the pancreas--a case report and review of the literature.
  • Most of the malignant neoplasms of the pancreas demonstrate features that are consistent with adenocarcinoma.
  • According to the WHO classification, primary clear cell carcinoma of the pancreas is rare and it is classified as a "miscellaneous" carcinoma.
  • We report here on an unusual case of primary pancreatic clear cell carcinoma, which is the first such reported case in Korea.
  • On the abdominal computed tomography (CT), we detected an abdominal mass involving the pancreas tail and liver, and clear cell carcinoma with rhabdoid feature was seen on the histologic evaluation.
  • The tumor cells showed well defined cell membranes, clear cytoplasm and prominent cell boundaries.
  • She was diagnosed with a primary pancreatic clear cell carcinoma with hepatic metastasis and she received palliative gemcitabine chemotherapy.
  • The patient died one month later of pancreatic cancer progression.

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Mod Pathol. 2008 Sep;21(9):1075-83 [18536653.001]
  • [Cites] JOP. 2007;8(3):330-4 [17495363.001]
  • [Cites] Histopathology. 1998 May;32(5):444-8 [9639120.001]
  • [Cites] Semin Diagn Pathol. 1997 Aug;14(3):213-9 [9279977.001]
  • [Cites] Semin Diagn Pathol. 1997 Aug;14(3):183-202 [9279975.001]
  • [Cites] Ann Diagn Pathol. 2002 Dec;6(6):381-4 [12478490.001]
  • [Cites] Arch Pathol Lab Med. 1989 Feb;113(2):113-4 [2916901.001]
  • [Cites] Acta Pathol Jpn. 1987 Sep;37(9):1521-6 [3687432.001]
  • [Cites] Arch Pathol Lab Med. 2004 Jun;128(6):693-6 [15163226.001]
  • [Cites] J Hepatobiliary Pancreat Surg. 2004;11(2):140-4 [15127279.001]
  • [Cites] Gastroenterology. 1991 Jan;100(1):233-8 [1983826.001]
  • (PMID = 19809568.001).
  • [ISSN] 1598-2998
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2757667
  • [Keywords] NOTNLM ; Clear cell carcinoma / Pancreas / Rhabdoid tumor
  •  go-up   go-down


15. Abdel-Ghaffar M: Large gastrointestinal stromal tumor size does not imply early recurrence. Int Med Case Rep J; 2010;3:13-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Large gastrointestinal stromal tumor size does not imply early recurrence.
  • Initially a mesenteric mass was diagnosed, but her tumor was found to be a gastrointestinal stromal tumor (GIST).
  • In order to remove the tumor, the left half of transverse colon with its mesocolon, spleen, body and tail of pancreas, and a part of the small intestine had to be removed.
  • The tumor was surgically removed three years ago.
  • The pathology report of the case presented places the tumor in the high-risk category.
  • The tumor had a relatively high mitotic index.
  • Although the patient did not receive adjuvant chemotherapy, no signs of local recurrence or distant metastasis could be recognized on follow up.
  • The tumor should be removed en bloc, with clear surgical margin.
  • The case presented indicates no association of tumor size with early local recurrence of the tumor or early distant metastasis.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 23754882.001).
  • [ISSN] 1179-142X
  • [Journal-full-title] International medical case reports journal
  • [ISO-abbreviation] Int Med Case Rep J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC3658213
  • [Keywords] NOTNLM ; GIST / gastrointestinal stromal tumor / metastasis
  •  go-up   go-down


16. Kaushal V, Goel A, Rattan KN, Yadav R, Mathur SK: Pancreatoblastoma. Indian J Pediatr; 2001 Nov;68(11):1075-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pancreatoblastoma is an extremely rare pancreatic tumor in childhood, comprising 0.5% of pancreatic non endocrine tumors.
  • Exploratory laparotomy revealed a large mass, arising from body and tail of pancreas, not infiltrating the adjacent structures.
  • Complete excision of the mass along with removal of body and tail of pancreas was done.
  • The role of adjuvant chemotherapy or radiotherapy is still under discussion due to small number of patients treated as yet.
  • [MeSH-major] Pancreatectomy / methods. Pancreatic Neoplasms / diagnosis. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Biopsy, Needle. Child. Follow-Up Studies. Humans. Laparotomy / methods. Male. Tomography, X-Ray Computed

  • Genetic Alliance. consumer health - Pancreatoblastoma.
  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Trop Gastroenterol. 1998 Apr-Jun;19(2):67-9 [9752756.001]
  • [Cites] Cancer. 1987 Oct 15;60(8):1734-6 [3115557.001]
  • [Cites] Gastroenterol Clin Biol. 1997;21(11):880-3 [9587540.001]
  • [Cites] Langenbecks Arch Chir Suppl Kongressbd. 1996;113:1040-2 [9101776.001]
  • [Cites] J Pediatr Surg. 2000 Nov;35(11):1663-5 [11083448.001]
  • [Cites] Cancer. 1984 Feb 15;53(4):963-9 [6141001.001]
  • [Cites] Minerva Chir. 1996 Sep;51(9):729-35 [9082240.001]
  • [Cites] Arch Pathol Lab Med. 1986 Jul;110(7):650-2 [3013120.001]
  • [Cites] Cancer. 1977 Jan;39(1):247-54 [188539.001]
  • [Cites] Eur J Pediatr Surg. 1996 Dec;6(6):369-72 [9007475.001]
  • [Cites] Med Pediatr Oncol. 1996 Sep;27(3):193-7 [8699999.001]
  • [Cites] Surgery. 1984 Apr;95(4):505 [6710348.001]
  • [Cites] Zhonghua Yi Xue Za Zhi (Taipei). 1994 Sep;54(3):198-203 [7954063.001]
  • [Cites] J Pediatr Surg. 1997 Nov;32(11):1612-5 [9396538.001]
  • (PMID = 11770246.001).
  • [ISSN] 0019-5456
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


17. Geener KJ, Feroze M, Geetha K, Jacob AJ: Papillary cystic tumor of pancreas--report of two cases. Indian J Pathol Microbiol; 2002 Jan;45(1):99-101
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Papillary cystic tumor of pancreas--report of two cases.
  • Two cases of Papillary cystic tumor of pancreas--one metastasizing to lymph node and the other non-metastasizing are reported for their rare occurrence.
  • On radiological examination, mass was arising from tail of pancreas and had typical gross features.
  • The histological findings seen in metastasizing tumor were capsular invasion, infiltration to surrounding pancreatic tissue and vascular invasion with metastasis to lymph node.
  • Adjuvant chemotherapy was given for metastasizing tumor and patient is symptom free after 56 month.
  • [MeSH-major] Carcinoma, Papillary / pathology. Pancreas / pathology. Pancreatic Cyst / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Lymphatic Metastasis. Neoplasm Invasiveness

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12593574.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  •  go-up   go-down


18. Kitami CE, Shimizu T, Sato O, Kurosaki I, Mori S, Yanagisawa Y, Ajioka Y, Hatakeyama K: Malignant islet cell tumor projecting into the main pancreatic duct. J Hepatobiliary Pancreat Surg; 2000;7(5):529-33
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant islet cell tumor projecting into the main pancreatic duct.
  • We report herein a rare case of islet cell tumor showing a unique growth pattern in a patient who developed repeated acute pancreatitis as the tumor's initial symptom.
  • Preoperative imaging examinations showed dilatation of the main pancreatic duct (MPD) and cysts around the pancreatic tail.
  • A distal pancreatectomy with splenectomy was performed because the pancreatitis was localized in the distal pancreas and was not controlled by various drug therapies.
  • Grossly, the tumor consisted of two component parts: a markedly infiltrative part in the pancreatic parenchyma, and a papillary elevated part in the MPD.
  • The MPD was obstructed by the tumor spreading widely along the distal MPD.
  • Microscopically, the tumor was composed entirely of islet cell tumors (nonfunctioning), with several foci of venous and lymphatic involvement.
  • Based on its growth behavior, we assumed that the tumor may have arisen from the MPD or from islet cells closely adjacent to the MPD.
  • We discuss the growth pattern of the tumor and the cause of the pancreatitis.
  • [MeSH-major] Carcinoma, Islet Cell / pathology. Pancreatic Ducts / pathology. Pancreatic Neoplasms / pathology
  • [MeSH-minor] Acute Disease. Humans. Male. Middle Aged. Neoplasm Invasiveness. Pancreatectomy. Pancreatitis / etiology

  • MedlinePlus Health Information. consumer health - Pancreatic Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11180883.001).
  • [ISSN] 0944-1166
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 22
  •  go-up   go-down






Advertisement