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1. Bergoeing R M, Mertens M R, Valdés E F, Krämer Sch A, Alvarez Z M, Bertin C P, Sagüés C R, Orellana U E, Galindo A H, Vergara G J, Valdebenito C M: [Endovascular treatment of superior vena cava syndrome]. Rev Med Chil; 2006 Jul;134(7):827-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Endovascular treatment of superior vena cava syndrome].
  • [Transliterated title] Tratamiento endovascular del síndrome de vena cava superior.
  • BACKGROUND: Superior vena cava syndrome (SVCS) is caused by the obstruction of venous drainage from the upper portion of the body.
  • AIM: to report our experience with endovascular treatment of SVCS.
  • MATERIAL AND METHODS: Retrospective review of all patients with SVCS subjected to endovascular treatment between 1999 and 2005.
  • Six had a benign obstruction due to the presence of a chemotherapy catheter located in the superior vena cava, one had obstruction secondary to radiation therapy and one a tumor compression of the superior vena cava.
  • Two patients underwent thrombolytic therapy.
  • The chemotherapy catheter was removed to all patients and installed again in one.
  • No patient died in relation to the procedure.
  • Congestive signs and symptoms subsided in all patients within 24 hours after the procedure.
  • During follow up, only one patient had symptoms related to vena cava obstruction and three died due to their malignant tumor.
  • CONCLUSIONS: Endovascular treatment of SVCS has a low rate of complications and provides immediate and mid-term symptom relief.
  • [MeSH-major] Angioplasty, Balloon. Stents. Superior Vena Cava Syndrome / therapy
  • [MeSH-minor] Adult. Aged. Catheterization / adverse effects. Female. Humans. Male. Middle Aged. Neoplasms / complications. Retrospective Studies. Treatment Outcome

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  • (PMID = 17130964.001).
  • [ISSN] 0034-9887
  • [Journal-full-title] Revista médica de Chile
  • [ISO-abbreviation] Rev Med Chil
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Chile
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2. Miyake M, Fujimoto K, Matsushita C, Chihara Y, Tanaka M, Hirayama A, Hirao Y, Uemura H: [Tumor thrombus arising from the superior vena cava and extending into the right atrium in a patient with advanced testicular germ cell tumor]. Hinyokika Kiyo; 2009 Jun;55(6):371-5
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  • [Title] [Tumor thrombus arising from the superior vena cava and extending into the right atrium in a patient with advanced testicular germ cell tumor].
  • Ultrasonography detected right testicular tumor and computerized tomography scanning revealed a left supraclavicular lymph node mass and bulky retroperitoneal lymph node mass.
  • He initially underwent right high orchiectomy, combination chemotherapy and retroperitoneal lymph node dissection for advanced testicular non-seminomatous germ cell tumor.
  • After complete remission of the lung metastasis with chemotherapy, the serum alpha-fetoprotein began to increase because of superior vena caval thrombus extending into the right atrium.
  • Emergency surgical excision was performed successfully using extracorporeal circulation to prevent pulmonary embolism and the resected specimen pathologically revealed adenocarcinoma interpreted as teratoma malignant transformation.
  • Adjuvant chemotherapy consisting of paclitaxel, ifosfamide and nedaplatin were administered for subsequent slight elevation of serum F-human chorionic gonadotropin beta, resulting in successful normalization again.
  • We report herein an extremely uncommon case of advanced testicular germ cell tumor with development of superior vena caval thrombus extending into the right atrium.
  • [MeSH-major] Heart Atria / pathology. Neoplasms, Germ Cell and Embryonal / pathology. Neoplastic Cells, Circulating / pathology. Testicular Neoplasms / pathology. Thrombosis / pathology. Vena Cava, Superior / pathology

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  • (PMID = 19588874.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin, beta Subunit, Human
  • [Number-of-references] 22
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3. Marcy PY, Thariat J, Bozec A, Poissonnet G, Benisvy D, Dassonville O: Venous obstruction of thyroid malignancy origin: the Antoine Lacassagne Institute experience. World J Surg Oncol; 2009;7:40
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  • RESULTS: Of 1171 patients with thyroid cancer treated at our institution over the last 18 years, we retrospectively identified nine patients (0.8%), three women and six men, aged 34-81 years (median age: 70 years) presenting with malignant thyroid tumor of median diameter 45 mm (range: 23-87) having venous obstruction of thyroid malignancy origin.
  • Two patients underwent multimodal therapy.
  • All other patients underwent external beam radiation therapy alone +/- chemotherapy or palliative care.
  • CONCLUSION: Despite small numbers of patients, it seems that aggressive treatment modalities including surgery are required to improve survival.
  • In our experience, US was a useful non-invasive method to describe tumor extensions to great veins of the neck (invasion versus compression, tumor thrombus versus blood clot) and should be recommended to depict early venous invasion in cases of suspected thyroid malignancy.
  • [MeSH-major] Superior Vena Cava Syndrome / etiology. Thyroid Neoplasms / complications

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  • [Cites] Radiology. 1999 May;211(2):579-83 [10228546.001]
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  • (PMID = 19374744.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2674443
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4. Higdon ML, Higdon JA: Treatment of oncologic emergencies. Am Fam Physician; 2006 Dec 1;74(11):1873-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of oncologic emergencies.
  • Most oncologic emergencies can be classified as metabolic, hematologic, structural, or side effects from chemotherapy agents.
  • Tumor lysis syndrome is a metabolic emergency that presents as severe electrolyte abnormalities.
  • Febrile neutropenia is a hematologic emergency that usually requires inpatient therapy with broad-spectrum antibiotics, although outpatient therapy may be appropriate for low-risk patients.
  • Hyperviscosity syndrome usually is associated with Waldenström's macroglobulinemia, which is treated with plasmapheresis and chemotherapy.
  • Superior vena cava syndrome presents as neck or facial swelling and development of collateral venous circulation.
  • Treatment options include chemotherapy, radiation, and intravenous stenting.
  • Malignant pericardial effusion, which often is undiagnosed in cancer patients, can be treated with pericardiocentesis or a pericardial window procedure.
  • [MeSH-minor] Blood Viscosity. Humans. Hypercalcemia / etiology. Hypercalcemia / therapy. Immunoglobulins / blood. Inappropriate ADH Syndrome / etiology. Inappropriate ADH Syndrome / therapy. Neutropenia / etiology. Neutropenia / therapy. Spinal Cord Compression / etiology. Spinal Cord Compression / therapy. Tumor Lysis Syndrome / etiology. Tumor Lysis Syndrome / therapy

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  • (PMID = 17168344.001).
  • [ISSN] 0002-838X
  • [Journal-full-title] American family physician
  • [ISO-abbreviation] Am Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Immunoglobulins
  • [Number-of-references] 38
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5. Takeda S, Miyoshi S, Ohta M, Minami M, Masaoka A, Matsuda H: Primary germ cell tumors in the mediastinum: a 50-year experience at a single Japanese institution. Cancer; 2003 Jan 15;97(2):367-76

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of the current study was to review the authors' institutional experience of mediastinal GCT, emphasizing the clinical spectrum, time trends of treatment, and recent advances in therapeutic modalities for malignant GCT.
  • METHODS: Between 1951 and 2000, 129 patients (70 males and 59 females) underwent surgical treatment for GCT, which accounted for 16.0% of the mediastinal tumors during the same period.
  • Eight of the 13 patients (61.5%) with seminoma were symptomatic and 10 of 13 patients (83.3%) survived after surgery and radiation with/without chemotherapy.
  • Nineteen of 21 patients (90.5%) with NSGCT had dyspnea, chest pain, and superior vena cava syndrome.
  • After 1986, six of eight patients received cisplatin-based chemotherapy, including three who received additional high-dose chemotherapy with a supporting peripheral blood stem cell transplantation until tumor markers normalized.
  • An improved survival advantage was ensured with cisplatin-based preoperative chemotherapy in patients with NSGCT.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Combined Modality Therapy. Female. Humans. Infant. Japan. Male. Middle Aged. Seminoma / diagnosis. Seminoma / epidemiology. Seminoma / therapy. Survival Analysis. Teratoma / diagnosis. Teratoma / epidemiology. Teratoma / therapy

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  • [Copyright] Copyright 2003 American Cancer Society
  • (PMID = 12518361.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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6. Yamamoto Y, Goto M, Okamoto T, Tomita I, Murayama A, Sawa M, Noguchi Y, Hoshikawa Y, Shimizu A: [Chemotherapy-naïve advanced malignant fibrohistiocytoma presenting IVC syndrome case report]. Gan To Kagaku Ryoho; 2010 Feb;37(2):355-7
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  • [Title] [Chemotherapy-naïve advanced malignant fibrohistiocytoma presenting IVC syndrome case report].
  • Computed tomography (CT) and 3 dimensional CT showed an 8-cm tumor on the IVC, partially replacing iliac vessels and invading the psoas muscle.
  • A diagnosis of malignant fibrohistiocytoma was made by pathological examination of biopsied specimens at exploratory laparotomy.
  • Five courses of combination chemotherapy of ifosfamide (IFM) and doxorubicin (DXR) resulted in PR.
  • Another 5 courses of chemotherapy with epirubicin and IFM were added.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Doxorubicin / therapeutic use. Histiocytoma, Malignant Fibrous / complications. Histiocytoma, Malignant Fibrous / drug therapy. Ifosfamide / therapeutic use. Superior Vena Cava Syndrome / etiology. Vena Cava, Inferior / pathology
  • [MeSH-minor] Aged. Biopsy. Humans. Male. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 20154502.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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7. Shiono S, Abiko M, Tamura G, Sato T: Malignant solitary fibrous tumor with superior vena cava syndrome. Gen Thorac Cardiovasc Surg; 2009 Jun;57(6):321-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant solitary fibrous tumor with superior vena cava syndrome.
  • Mediastinal solitary fibrous tumors, particularly those that are malignant, are rare.
  • We report a case of malignant solitary fibrous tumor with superior vena cava syndrome and highly aggressive behavior.
  • Postoperative radiotherapy was performed due to incomplete resection, but the tumor relapsed within 4 months.
  • Gemcitabine-based chemotherapy was ineffective.
  • [MeSH-major] Mediastinal Neoplasms / complications. Solitary Fibrous Tumors / complications. Superior Vena Cava Syndrome / etiology
  • [MeSH-minor] Adult. Deoxycytidine / analogs & derivatives. Deoxycytidine / therapeutic use. Fatal Outcome. Female. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Neoplasm Invasiveness. Pleural Neoplasms / drug therapy. Pleural Neoplasms / secondary. Radiotherapy, Adjuvant. Sternum / surgery. Tomography, X-Ray Computed. Treatment Outcome. Vascular Surgical Procedures

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  • [Cites] Chest. 2007 Mar;131(3):904-908 [17356113.001]
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  • (PMID = 19533281.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine
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8. Shintani Y, Ohta M, Hazama K, Miyoshi S, Kagisaki K, Matsuda H: Thymic carcinoma successfully resected with superior vena cava after chemoradiotherapy. Jpn J Thorac Cardiovasc Surg; 2001 Dec;49(12):717-21
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  • [Title] Thymic carcinoma successfully resected with superior vena cava after chemoradiotherapy.
  • A 57-year-old woman hospitalized for thymic cancer invading the superior vena cava and left brachiocephalic vein evidenced both pleural and pericardial effusion.
  • After chemotherapy with cisplatin and docetaxel and concurrent radiotherapy, the entire tumor was successfully resected along with the pericardium, superior vena cava, and left brachiocephalic vein, followed by vascular reconstruction.
  • Pathologically, viable tumor cells were identified only in the center of the tumor as anaplastic cell carcinoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma / surgery. Paclitaxel / analogs & derivatives. Taxoids. Thymus Neoplasms / surgery. Vena Cava, Superior / surgery
  • [MeSH-minor] Cisplatin / administration & dosage. Combined Modality Therapy. Drug Administration Schedule. Female. Humans. Middle Aged. Pericardial Effusion / etiology. Pleural Effusion, Malignant / etiology

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  • (PMID = 11808095.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Taxoids; 15H5577CQD / docetaxel; P88XT4IS4D / Paclitaxel; Q20Q21Q62J / Cisplatin
  • [Number-of-references] 10
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9. Souzaki R, Tajiri T, Kinoshita Y, Tanaka S, Koga Y, Suminoe A, Hara T, Kohashi K, Oda Y, Taguchi T: Successful treatment of advanced pancreatoblastoma by a pylorus-preserving pancreatoduodenectomy after radiation and high-dose chemotherapy. Pediatr Surg Int; 2010 Oct;26(10):1045-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Successful treatment of advanced pancreatoblastoma by a pylorus-preserving pancreatoduodenectomy after radiation and high-dose chemotherapy.
  • BACKGROUND: Pancreatoblastoma (PB) is a rare malignant pancreatic tumor in children and approximately 200 cases have been reported in the literature.
  • The overall 5-year survival rate in PB is 43-50% and no standard treatment for PB has been established.
  • This report presents the case of a 6-year-old female with advanced PB treated successfully by a pylorus-preserving pancreatoduodenectomy (PPPD) after induction chemotherapy, radiation and stem cell transplantation (SCT).
  • Abdominal computed tomography (CT) scan showed a 9-cm heterogeneous mass located at the pancreatic head and body, and the duodenum was completely compressed.
  • The inferior vena cava, superior mesenteric artery, and vein were encased by the tumor.
  • The tumor had well-defined margins and calcification.
  • Initially, a resection of the tumor was impossible.
  • She underwent five cycles of the induction chemotherapy regimen for advanced neuroblastoma (cyclophosphamide, etoposide, vincristine, pirarubicin and cisplatin), and the tumor size was decreased to a diameter of 7.5 cm.
  • Furthermore, chemotherapy with irinotecan and vincristine, radiotherapy (40 Gy) and SCT (etoposide, carboplatin, melphalan) was administered.
  • The serum AFP level decreased to 41.1 ng/ml, and the tumor size was decreased to a diameter of 6.5 cm.
  • Then she underwent a PPPD and the tumor was completely resected.
  • The child was administered mild postoperative chemotherapy using irinotecan and has been disease-free for 4 months and, and her serum AFP levels remain within normal values.
  • The combined therapy including the intensive chemotherapy with SCT and the radiation followed by surgical treatment is thought to be effective for the treatment of advanced PB.
  • [MeSH-minor] Child. Female. Follow-Up Studies. Humans. Pancreatic Neoplasms / drug therapy. Pancreatic Neoplasms / radiotherapy. Pancreatic Neoplasms / surgery. Radiotherapy, Adjuvant

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  • (PMID = 20632017.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; Pancreatoblastoma
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10. Halloul Z, Weber M, Ricke J, Smith B, Meyer F: Hybrid approach: vascular surgical and image-guided intervention for BroCa-induced superior vena cava syndrome (SVCS). Thorac Cardiovasc Surg; 2009 Oct;57(7):427-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hybrid approach: vascular surgical and image-guided intervention for BroCa-induced superior vena cava syndrome (SVCS).
  • BACKGROUND: The aim of this study was to compare the outcome of a novel hybrid technique with the results of conventional approaches when treating tumor-induced superior vena cava syndrome (SVCS).
  • The failure of a thrombectomy via transjugular aspiration led to an interdisciplinary approach to treat malignant SVCS.
  • RESULTS: Tumor-induced SVCS is an urgent case that sometimes cannot wait for radiotherapy or chemotherapy to reduce the tumor mass compressing the SVC.
  • CONCLUSION: Treatment provided the advantages associated with limited invasiveness, i.e., a faster and complication-free recovery period.
  • The procedure may be a suitable alternative to open surgical intervention, as it involves less invasive trauma and has a reasonable risk-benefit ratio with a good chance of technical and clinical success.
  • [MeSH-major] Balloon Occlusion / instrumentation. Brachiocephalic Veins. Carcinoma, Bronchogenic / complications. Lung Neoplasms / complications. Stents. Subclavian Vein. Superior Vena Cava Syndrome / therapy. Thrombectomy. Venous Thrombosis / therapy
  • [MeSH-minor] Aged. Angiography, Digital Subtraction. Combined Modality Therapy. Disease Progression. Fatal Outcome. Humans. Male. Radiography, Interventional. Suction. Suture Techniques. Treatment Outcome

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  • [Copyright] Georg Thieme Verlag KG Stuttgart. New York.
  • (PMID = 19795334.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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11. Fuchida S, Yamada N, Uchida R, Okano A, Okamoto M, Ochiai N, Shimazaki C: Malignant lymphoma presenting as a cardiac tumor and superior vena caval syndrome successfully treated by haploidentical stem cell transplantation. Leuk Lymphoma; 2005 Oct;46(10):1517-21
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  • [Title] Malignant lymphoma presenting as a cardiac tumor and superior vena caval syndrome successfully treated by haploidentical stem cell transplantation.
  • A 16 year-old male with B-cell non-Hodgkin's lymphoma presenting as a cardiac tumor and superior vena caval (SVC) syndrome received a haploidentical stem cell transplant (SCT) from his mother after conventional and salvage chemotherapy.
  • He received additional radiation therapy for the residual tumor and is alive and well on day 640 after transplantation.
  • Malignant lymphoma presenting as a cardiac tumor, including primary cardiac lymphoma, is rare.
  • Although many reports have shown the poor prognosis of cardiac lymphoma, our case suggests that allogeneic haploidentical SCT might be useful for the treatment of aggressive cardiac lymphoma.
  • [MeSH-major] Heart Neoplasms / complications. Heart Neoplasms / diagnosis. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / surgery. Stem Cell Transplantation. Superior Vena Cava Syndrome / complications. Superior Vena Cava Syndrome / diagnosis

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  • (PMID = 16194899.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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12. Belmadani K, Amahzoune B, Selkane C, Boulahya A, el Fakir Y, al Bouzidi A, el Kirat A: [Invasive thymoma extending into the superior vena cava and the right atrium: a case report and review of the literature]. Ann Cardiol Angeiol (Paris); 2001 Jun;50(4):217-23
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  • [Title] [Invasive thymoma extending into the superior vena cava and the right atrium: a case report and review of the literature].
  • If the neoplastic extension with the higher vena cava can be observed during the evolution of the invasive thymomes, the tumoral extension in the right auricle, remains on the other hand an exception.
  • The transthoracic echocardiography supplemented by the echocardiography transoesophageal pose the cardiac diagnosis of tumor, and it is the thoracic tomodensitometry which highlights a tumoral process mediastinal of malignant pace invading the left inominal venous trunk, the higher vena cava and extending in the right auricle.
  • Under chemotherapy, the evolution over 18 months is marked by the absence of cardiovascular complications in spite of the non regression of the tumoral mass.
  • The surgery when it is possible, remains the principal therapeutic measurement which really proved reliable.
  • [MeSH-major] Heart Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Thymoma / diagnosis. Thymus Neoplasms / diagnosis. Vascular Neoplasms / diagnosis. Vena Cava, Superior
  • [MeSH-minor] Aged. Heart Atria. Humans. Male. Neoplasm Invasiveness

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  • (PMID = 12555596.001).
  • [ISSN] 0003-3928
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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13. Matsuo S, Sato Y, Miyamoto A, Nakae I, Saeki M, Hodohara K, Horie M: Primary malignant lymphoma of the right atrium resulting in superior vena caval syndrome in an HIV-positive patient: depiction at multislice computed tomography and magnetic resonance imaging. Cardiovasc Revasc Med; 2006 Oct-Dec;7(4):255-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary malignant lymphoma of the right atrium resulting in superior vena caval syndrome in an HIV-positive patient: depiction at multislice computed tomography and magnetic resonance imaging.
  • An HIV-positive 32-year-old male presenting with superior vena cava syndrome underwent multislice computed tomography (MSCT) and magnetic resonance imaging (MRI), which showed a large tumor in the right atrium, which extended to the superior vena cava.
  • Pathologic examination revealed that the mass was consistent with B cell-type malignant lymphoma.
  • The tumor size markedly decreased after the initiation of chemotherapy and patient recovery has been uneventful for 1 year.
  • [MeSH-major] HIV Seropositivity. Heart Atria. Heart Neoplasms / complications. Lymphoma / complications. Magnetic Resonance Imaging. Superior Vena Cava Syndrome / etiology. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Humans. Male. Prednisone / therapeutic use. Vincristine / therapeutic use


14. Baltayiannis N, Magoulas D, Anagnostopoulos D, Bolanos N, Sfyridis P, Georgiannakis E, Zografos P, Kayia A, Kayianni E, Sotirakoglou K, Chatzimichalis A: Percutaneous stent placement in malignant cases of superior vena cava syndrome. J BUON; 2005 Jul-Sep;10(3):377-80

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Percutaneous stent placement in malignant cases of superior vena cava syndrome.
  • PURPOSE: Superior vena cava (SVC) syndrome is caused by SVC stenosis or occlusion, frequently as a consequence of lung cancer or a mediastinal tumor.
  • Treatment with radiation therapy and chemotherapy may produce an initial relief, whereas operations with bypass are associated with high mortality and morbidity.
  • The PURPOSE of our study was to show the efficiency of percutaneous stenting in the SVC for relieving SVC syndrome secondary to malignant diseases.
  • PATIENTS AND METHODS: From January 1999 to March 2003, 17 patients with malignant SVC syndrome were evaluated at the "Metaxa" Cancer Hospital.
  • Their caval stenoses were confirmed by means of computed tomography and venography.
  • The SCV syndrome was caused by malignant disease in all patients: bronchogenic carcinoma in 14 and lymphoma in 3.
  • All patients underwent placement of a self-expandable (wallstent) endovascular (vena cava) prosthesis.
  • The average time for wallstent placement was 37 min.
  • CONCLUSION: Percutaneous venous wallstent placement in the SVC is a simple, safe and effective technique to rapidly relieve SVC syndrome caused by malignant diseases.

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  • (PMID = 17357192.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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15. Marcy PY, Magné N, Bentolila F, Drouillard J, Bruneton JN, Descamps B: Superior vena cava obstruction: is stenting necessary? Support Care Cancer; 2001 Mar;9(2):103-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Superior vena cava obstruction: is stenting necessary?
  • No therapy is currently available for patients with recurrent vascular obstruction of the superior vena cava (SVC) caused by tumor regrowth after chemotherapy or radiation therapy.
  • Intravascular stenting is a new option for the treatment of vena cava syndrome.
  • Forty cancer patients with SVC syndrome (SVCS) were evaluated by computed tomography (CT) and venography.
  • The etiology was malignant in all but 2 cases: non-small-cell lung carcinoma (n = 28), mediastinal nodal metastasis (n = 5), lymphoma (n = 2), pleural mesothelioma (n = 2), small-cell lung carcinoma (n = 1), and postradiation fibrous mediastinitis (n = 2).
  • [MeSH-major] Stents. Superior Vena Cava Syndrome / therapy

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  • (PMID = 11305067.001).
  • [ISSN] 0941-4355
  • [Journal-full-title] Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
  • [ISO-abbreviation] Support Care Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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16. Kang CH, Kim YT, Jheon SH, Sung SW, Kim JH: Surgical treatment of malignant mediastinal nonseminomatous germ cell tumor. Ann Thorac Surg; 2008 Feb;85(2):379-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of malignant mediastinal nonseminomatous germ cell tumor.
  • BACKGROUND: The aim of this study was to evaluate the role of surgical treatment for mediastinal nonseminomatous germ cell tumors (MNSGCT) and identify the factors of long-term survival.
  • Three different regimens were used for preoperative chemotherapy, and 14 patients (66.7%) achieved partial response, 4 (19.0%) had stable disease, and 2 (9.5%) had progressive disease.
  • Concomitantly resected organs were lung in 13 patients (61.9%) and superior vena cava in 5 (23.8%).
  • Viable germ cell tumor was identified in pathology specimens in 12 (57.1%), total necrosis in 7 (33.3%), and remnant teratoma in 2 (9.5%).
  • CONCLUSIONS: Surgical resection of MNSGCT after chemotherapy showed favorable long-term survival.
  • An elevated beta-HCG level at initial diagnosis was associated with a poor prognosis despite multimodality therapy.
  • [MeSH-major] Chorionic Gonadotropin, beta Subunit, Human / blood. Mediastinal Neoplasms / mortality. Mediastinal Neoplasms / surgery. Neoplasm Recurrence, Local / mortality. Neoplasms, Germ Cell and Embryonal / mortality. Neoplasms, Germ Cell and Embryonal / surgery
  • [MeSH-minor] Adolescent. Adult. Analysis of Variance. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / blood. Biopsy, Needle. Chemotherapy, Adjuvant. Child. Combined Modality Therapy. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Preoperative Care / methods. Probability. Prognosis. Proportional Hazards Models. Registries. Retrospective Studies. Risk Assessment. Survival Analysis. Thoracotomy / methods. Treatment Outcome

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  • (PMID = 18222229.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin, beta Subunit, Human
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17. Ohta Y, Iino K, Tamura M, Katayanagi K, Kurumaya H: Extended resection of mediastinal undifferentiated carcinoma after chemosensitivity test-guided induction treatment: report of a case. Surg Today; 2005;35(2):139-41

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Extended resection of mediastinal undifferentiated carcinoma after chemosensitivity test-guided induction treatment: report of a case.
  • We performed extended resection of primary mediastinal undifferentiated carcinoma, together with the superior vena cava and the upper lobe of the right lung, after effective induction chemoradiation therapy based on the results of a chemosensitivity test.
  • Pathological examination of the resected specimen revealed that almost all of the tumor cells had died.
  • The patient received adjuvant chemotherapy and has remained free from disease progression for 27 months since his operation.
  • Our experience supports the effectiveness of an aggressive approach, in the form of chemosensitivity test-guided induction therapy, to treat this high-grade malignant disease, despite the risk of cancer dissemination.
  • [MeSH-major] Carcinoma / drug therapy. Carcinoma / surgery. Mediastinal Neoplasms / drug therapy. Mediastinal Neoplasms / surgery
  • [MeSH-minor] Chemotherapy, Adjuvant. Combined Modality Therapy. Humans. Lung / surgery. Male. Middle Aged. Remission Induction. Vena Cava, Superior / surgery

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  • (PMID = 15674495.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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18. Skopin II, Serov RA, Makushin AA, Sazonenkov MA: Primary rhabdomyosarcoma of the right atrium. Interact Cardiovasc Thorac Surg; 2003 Sep;2(3):316-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rhabdomyosarcoma is the rare malignant tumor of the heart.
  • A case of a large malignant rhabdomyosarcoma in a 37 year old woman is presented.
  • The tumor arose from the anterior wall of the right atrium and was treated by surgical resection with replacement of the tricuspid valve with bioprosthesis.
  • The patient passed two courses of adjuvant chemotherapy.
  • Six months later transthoracic echocardiography revealed absence of any tissue masses in right atrium, superior vena cava and normal function of the bioprosthesis.

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  • (PMID = 17670056.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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19. Li Q, Feng FY, Chen Q, Jiao SC, Li F, Wang HQ, Huang WX, Ling CQ, Li MZ, Ren J, Zhang Y, Qin FZ, Zhou MZ, Zhu RZ: [Multicenter phase II clinical trial of uroacitides injection in the treatment for advanced malignant tumors]. Zhonghua Zhong Liu Za Zhi; 2008 Jul;30(7):534-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multicenter phase II clinical trial of uroacitides injection in the treatment for advanced malignant tumors].
  • OBJECTIVE: To investigate the efficacy, safety and the life quality improvement of uroacitides injection in the treatment for patients with advanced malignant tumors.
  • Uroacitides was administrated in a dose of 300 ml daily via the superior vena cava catheter for consecutive 4-8 weeks.
  • The total objective response rate (ORR, CR + PR)) and tumor control rate (CR + PR + MR + SD) of the 138 evaluable patients were 5.8% and 65.2%, respectively.
  • [MeSH-major] Liver Neoplasms / drug therapy. Lung Neoplasms / drug therapy. Methyltransferases / therapeutic use. Peptides / therapeutic use. Phenylacetates / therapeutic use
  • [MeSH-minor] Breast Neoplasms / blood. Breast Neoplasms / drug therapy. Breast Neoplasms / pathology. CA-19-9 Antigen / blood. Carcinoembryonic Antigen / blood. Carcinoma, Non-Small-Cell Lung / blood. Carcinoma, Non-Small-Cell Lung / drug therapy. Carcinoma, Non-Small-Cell Lung / pathology. Catheterization, Central Venous. Colorectal Neoplasms / blood. Colorectal Neoplasms / drug therapy. Colorectal Neoplasms / pathology. Humans. Nausea / chemically induced. Neoplasm Staging. Quality of Life. Remission Induction. Salvage Therapy. Treatment Outcome. Vomiting / chemically induced. alpha-Fetoproteins / metabolism

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  • (PMID = 19062723.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] Clinical Trial, Phase II; English Abstract; Journal Article; Multicenter Study
  • [Publication-country] China
  • [Chemical-registry-number] 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen; 0 / Peptides; 0 / Phenylacetates; 0 / alpha-Fetoproteins; 0 / cell differentiation agent II; EC 2.1.1.- / Methyltransferases
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20. Sentani K, Nakanishi Y, Ojima H, Hamaguchi T, Shimoda T: Esophageal squamous cell carcinoma presenting with systemic arterial embolism. Pathol Int; 2007 Feb;57(2):96-100
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  • Acute arterial occlusion as a result of embolization from a malignant tumor is rare and infrequently reported.
  • Although scheduled to undergo chemotherapy, he died of acute pneumonia on the 81st day from onset.
  • Autopsy showed superficial esophageal cancer, measuring 1.5 cm in diameter, and widespread tumor extension into arterial vessels such as the left femoral artery, the superior mesenteric artery, bilateral intrapulmonary arteries and veins such as bilateral brachiocephalic vein to the supra vena cava, despite small tumor size and shallow tumor invasion depth of the submucosal layer.
  • [MeSH-minor] Aged. Diagnosis, Differential. Femoral Artery / pathology. Humans. Male. Mesenteric Artery, Superior / pathology. Pulmonary Artery / pathology

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  • (PMID = 17300674.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 17
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21. Takeda S, Hirano H, Maeda H, Sawabata N, Okumura Y, Asada H: Thymic carcinoma with a large cystic lesion. Jpn J Thorac Cardiovasc Surg; 2004 Dec;52(12):574-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A computed tomography (CT) and magnetic resonance imaging showed a well-circumscribed cystic mass, 12 cm in size adjacent to the heart border and superior vena cava (SVC).
  • A CT guided needle biopsy was performed, and instead of detecting malignant tissues but finding that gray muddy fluid was suctioned, suggesting cystic teratoma.
  • At surgery, the tumor was confirmed advanced thymic carcinoma with pleural dissemination, then the tumor was extirpated with resection of SVC, followed by 2 cycles of chemotherapy.
  • Histologically, the cystic wall was lined with malignant cells.
  • [MeSH-minor] Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed. Vena Cava, Superior / surgery

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  • (PMID = 15651404.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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22. Rassweiler J, Prager P, Haferkamp A, Alken P, Kauffmann GW, Richter G: Transarterial nephrectomy: the current status of experimental and clinical studies. J Endourol; 2008 Apr;22(4):767-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For several years, minimally invasive alternatives have been developed such as laparoscopic nephrectomy or transarterial renal ablation.
  • MATERIALS AND METHODS: Based on own in vitro studies, the principle of capillary embolization with occlusion of the entire arterial system up to the capillaries by a precipitating corn protein (Ethibloc) has been developed in animal studies (i.e., rat and canine kidney model).
  • Once the capillary bed and tumor sinusoids are reached, the balloon catheter is emptied by postinjection of 40% glucose.
  • RESULTS: Capillary embolization proved to be significantly superior to a central (i.e., ligation of renal artery) or peripheral type of occlusion resulting in complete coagulation necrosis of the normal rat and canine kidney with reduction of the elevated blood pressure, similar to nephrectomy in the model of renal hypertension.
  • The procedure was relatively well tolerated and usually associated with a mild postembolization syndrome.
  • After an interval of up to 28 days, complete necrosis of the renal tumor could be achieved in tumors up to 9 cm in diameter.
  • Hematuria ceased in all cases, and in selected cases long-lasting responses of very large tumors (i.e., vena cava involvement) could be achieved.
  • DISCUSSION: Capillary chemoembolization represents an effective concept for ablation of malignant renal tumors.
  • It offers control of tumor growth in case of temporary inoperability as well as cessation of hematuria in a palliative situation.
  • Because of the local ablative efficiency, it may still represent a minimally invasive option in advanced stages of renal carcinoma (i.e., in combination with immunochemotherapy or targeted therapy).

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  • (PMID = 18366320.001).
  • [ISSN] 0892-7790
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drug Combinations; 0 / Fatty Acids; 0 / Propylene Glycols; 0 / Sclerosing Solutions; 117-96-4 / Diatrizoate; 9010-66-6 / Zein; 91196-33-7 / alcoholic prolamine solution; M43H21IO8R / Dimethylnitrosamine
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23. Lucchi M, Viti A, Melfi F, Ambrogi M, Givigliano F, Dini P, Mussi A: IIIB-T4 non-small cell lung cancer: indications and results of surgical treatment. J Cardiovasc Surg (Torino); 2007 Jun;48(3):369-74
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] IIIB-T4 non-small cell lung cancer: indications and results of surgical treatment.
  • We have reviewed our experience with T4 NSCLC patients who underwent surgery with the aim of debating the indications and results of surgical treatment in this highly selected group of patients.
  • The tumors were classified T4 for the following reasons: intralobar satellite metastasis in 24 cases, direct mediastinum invasion in 18 cases, malignant pleural effusion in 7 cases, involvement of the superior vena cava in 4 cases, marginal invasion of the vertebral body in 3 cases, involvement of the carena in 3 cases and invasion of the left atrium in 1 case.
  • Thirteen patients had undergone neo-adjuvant chemotherapy while 39 underwent adjuvant therapies.
  • The prognosis was neither affected by the subtype of T4 tumor nor by the use of adjuvant therapies and/or neoadjuvant chemotherapy but only by the N status.
  • [MeSH-minor] Aged. Aged, 80 and over. Chemotherapy, Adjuvant. Female. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Lymph Nodes / pathology. Lymphatic Metastasis / diagnosis. Male. Mediastinoscopy. Middle Aged. Neoadjuvant Therapy. Neoplasm Invasiveness. Neoplasm Staging / methods. Radiotherapy, Adjuvant. Risk Assessment. Risk Factors. Thoracic Surgery, Video-Assisted. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17505443.001).
  • [ISSN] 0021-9509
  • [Journal-full-title] The Journal of cardiovascular surgery
  • [ISO-abbreviation] J Cardiovasc Surg (Torino)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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24. Haas AR: Recent advances in the palliative management of respiratory symptoms in advanced-stage oncology patients. Am J Hosp Palliat Care; 2007 Apr-May;24(2):144-51
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  • Advanced-stage malignancies are often characterized by systemic complications related to primary tumor progression.
  • Although cancer-induced cough can be improved with radiation therapy or chemotherapy, or both, it is often best managed with central-acting opioids.
  • Dyspnea can arise from a range of etiologies that may or may not be related to the underlying malignant pulmonary disease.
  • Recent advances in the management of malignant pleural effusion, central airway obstruction, and superior vena cava syndrome have allowed relatively noninvasive interventions to be performed that can significantly reduce dyspnea, minimize inpatient hospitalization, and improve the quality of life in patients where the major focus is palliative care.
  • [MeSH-major] Neoplasms / complications. Palliative Care. Respiratory Tract Diseases / therapy
  • [MeSH-minor] Cough / etiology. Cough / therapy. Dyspnea / etiology. Dyspnea / therapy. Humans

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  • (PMID = 17502441.001).
  • [ISSN] 1049-9091
  • [Journal-full-title] The American journal of hospice & palliative care
  • [ISO-abbreviation] Am J Hosp Palliat Care
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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25. Tannuri AC, Tannuri U, Gibelli NE, Romão RL: Surgical treatment of hepatic tumors in children: lessons learned from liver transplantation. J Pediatr Surg; 2009 Nov;44(11):2083-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of hepatic tumors in children: lessons learned from liver transplantation.
  • Ultrasonography, computed tomographic (CT) scan, and needle biopsy were the initial methods used to diagnose malignant tumors.
  • After neoadjuvant chemotherapy, tumor resectability was evaluated by another CT scan.
  • The main arterial anomalies found were the right hepatic artery emerging from the superior mesenteric artery and left hepatic artery from left gastric artery.
  • During dissection of the suprahepatic veins, the venous infusion was decreased to reduce central venous pressure and potential bleeding from hepatic veins and the vena cava.
  • RESULTS: Fifty-three children with hepatic tumors underwent surgical treatment, 47 patients underwent liver resections, and in 6 cases, liver transplantation was performed because the tumor was considered unresectable.
  • Ten children presented with other malignant tumors-3 undifferentiated sarcomas, 2 hepatocellular carcinomas, 2 fibrolamellar hepatocellular carcinomas, a rhabdomyosarcoma, an immature ovarian teratoma, and a single neuroblastoma.
  • The overall mortality rate was 14.9%, and all deaths were related to recurrence of malignant disease.
  • The mortality rate of hepatoblastoma patients was less than other malignant tumors (P = .04).
  • [MeSH-minor] Age Factors. Blood Loss, Surgical. Carcinoma, Hepatocellular / mortality. Carcinoma, Hepatocellular / surgery. Follow-Up Studies. Hepatectomy / methods. Hepatoblastoma / mortality. Hepatoblastoma / surgery. Humans. Infant. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / surgery. Postoperative Complications / etiology. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 19944212.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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