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1. Franco MI, Waisberg J, Lopes LS: Multiple lymphomatous polyposis of the gastrointestinal tract. Sao Paulo Med J; 2004 May 6;122(3):131-3

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  • [Title] Multiple lymphomatous polyposis of the gastrointestinal tract.
  • CONTEXT: Gastrointestinal multiple lymphomatous polyposis is a rare type of malignant lymphoma that has aggressive biological behavior, early systemic dissemination and poor prognosis.
  • OBJECTIVE: A case of gastrointestinal multiple lymphomatous polyposis is presented and the anatomopathological, clinical, diagnostic and treatment aspects of this unusual neoplasia are discussed.
  • CASE REPORT: The patient was a 59-year-old white male with a complaint of asthenia, night sweating, alteration in intestinal habit and weight loss over the preceding two months.
  • An opaque enema showed multiple polypoid lesions, especially in the cecum.
  • After two cycles of chemotherapy there was a worsening of the general state, with an increase in the dimensions of the abdominal masses and sepsis, accompanied by progressive respiratory insufficiency, leading to death.
  • [MeSH-major] Gastrointestinal Neoplasms / pathology. Intestinal Polyposis / pathology. Lymphoma, Mantle-Cell / pathology

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  • (PMID = 15448813.001).
  • [ISSN] 1516-3180
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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2. Meral M, Demirpençe M, Gönen C, Akarsu M, Kayahan H, Demirkan F, Kargi A, Akpinar H: Diffuse gastrointestinal involvement of mantle cell lymphoma. Turk J Gastroenterol; 2008 Jun;19(2):117-20
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  • The most frequent endoscopic finding of mantle cell lymphoma is multiple lymphomatous polyposis, which is a very rare entity.
  • Multiple lymphomatous polyposis is characterized by multiple polypoid lesions involving long segments of the gastrointestinal tract and it accounts for 2% of primary gastrointestinal tract lymphomas.
  • Multiple lymphomatous polyposis was detected on the endoscopic evaluations.
  • The patient was successfully treated by combination chemotherapy.
  • [MeSH-major] Intestinal Neoplasms / diagnosis. Intestinal Polyposis / diagnosis. Lymphoma, Mantle-Cell / diagnosis. Stomach Neoplasms / diagnosis
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Barium. Biopsy. Colon / pathology. Contrast Media. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Endoscopy, Digestive System. Humans. Intestine, Small / pathology. Male. Prednisolone / administration & dosage. Tomography, X-Ray Computed. Vincristine / administration & dosage

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  • (PMID = 19110668.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  • [Chemical-registry-number] 0 / Contrast Media; 24GP945V5T / Barium; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone
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3. Kella VK, Constantine R, Parikh NS, Reed M, Cosgrove JM, Abo SM, King S: Mantle cell lymphoma of the gastrointestinal tract presenting with multiple intussusceptions--case report and review of literature. World J Surg Oncol; 2009;7:60
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  • [Title] Mantle cell lymphoma of the gastrointestinal tract presenting with multiple intussusceptions--case report and review of literature.
  • BACKGROUND: Mantle cell lymphoma (MCL) is an aggressive type of B-cell non-Hodgkin's lymphoma that originates from small to medium sized lymphocytes located in the mantle zone of the lymph node.
  • Extra nodal involvement is present in the majority of cases, with a peculiar tendency to invade the gastro-intestinal tract in the form of multiple lymphomatous polyposis.
  • Here we present a rare case of multiple intussusceptions caused by mantle cell lymphoma and review the literature of this disease.
  • Laparoscopy confirmed multiple intussusceptions involving ileo-colic and ileo-ileal segments of gastrointestinal tract.
  • The histology and immuno-histochemistry of the excised small and large bowel revealed mantle cell lymphoma with multiple lymphomatous polyposis and positivity to Cyclin D1 marker.
  • The patient was successfully treated with Rituximab-CHOP chemotherapy and remains in complete remission at one-year follow-up.
  • CONCLUSION: This is a rare case of intestinal lymphomatous polyposis due to mantle cell lymphoma presenting with multiple small bowel intussusceptions.
  • Our case highlights laparoscopic-assisted bowel resection as a potential and feasible option in the multi-disciplinary treatment of mantle cell lymphoma.


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4. García Aguilera X, González Martín JA, Peñas García B, Vázquez Sequeiros E, Montalbán Sanz C, Redondo Verge C: [Multiple lymphomatous polyposis, favorable outcome after chemotherapy]. Gastroenterol Hepatol; 2009 Oct;32(8):562-4
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  • [Title] [Multiple lymphomatous polyposis, favorable outcome after chemotherapy].
  • [Transliterated title] Poliposis linfomatosa múltiple, evolución favorable tras tratamiento quimioterapéutico.
  • Multiple lymphomatous polyposis is a rare type of non Hodgkin lymphoma that has aggressive biological behavior, early systemic dissemination and poor prognosis.
  • We describe a case of a 55 year old man, with favorable outcome after chemotherapy.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Intestinal Polyposis / drug therapy. Lymphoma, Mantle-Cell / drug therapy

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  • (PMID = 19523717.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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5. Hsieh YC, Lin CL, Tsao CJ, Hsieh PP, Tzeng CC, Chuang SS: Aberrant expression of CD19 and CD43 in a patient with therapy-related acute myeloid leukemia and a history of mantle cell lymphoma. Kaohsiung J Med Sci; 2009 Jul;25(7):389-94
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  • [Title] Aberrant expression of CD19 and CD43 in a patient with therapy-related acute myeloid leukemia and a history of mantle cell lymphoma.
  • In patients with a prior history of MCL with PB involvement, the appearance of leukemic cells after chemotherapy usually heralds a relapse, particularly if the leukemic cells express B cell markers and CD43.
  • We report a patient with MCL who presented with multiple lymphomatous polyposis of the intestine.
  • Three years after chemotherapy, thrombocytopenia with the appearance of rare leukemic cells in the PB was noted.
  • Detailed cytomorphological and immunophenotypic studies unveiled the myeloid nature of these leukemic cells, and a diagnosis of therapy-related acute myeloid leukemia was made.
  • This case illustrates the importance of morphologic examination and performing a complete antibody panel in the diagnosis of a suspected relapse in patients with a prior history of lymphoma.

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  • (PMID = 19605331.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 0 / Antigens, CD19; 0 / Antigens, CD43
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6. Watanabe T, Homma N, Ogata N, Saito H, Kanefuji T, Hasegawa K, Soga K, Shibasaki K, Endo T, Ajioka Y: Complete response in a patient with colonic mantle cell lymphoma with multiple lymphomatous polyposis treated with combination chemotherapy using anti-CD20 antibody and cladribine. Gut; 2007 Mar;56(3):449-50
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  • [Title] Complete response in a patient with colonic mantle cell lymphoma with multiple lymphomatous polyposis treated with combination chemotherapy using anti-CD20 antibody and cladribine.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Colonic Neoplasms / drug therapy. Lymphoma, Mantle-Cell / drug therapy

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  • (PMID = 17339260.001).
  • [ISSN] 0017-5749
  • [Journal-full-title] Gut
  • [ISO-abbreviation] Gut
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 47M74X9YT5 / Cladribine; 4F4X42SYQ6 / Rituximab
  • [Other-IDs] NLM/ PMC1856801
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7. Hokama A, Tomoyose T, Yamamoto Y, Watanabe T, Hirata T, Kinjo F, Kato S, Ohshima K, Uezato H, Takasu N, Fujita J: Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis. World J Gastroenterol; 2008 Nov 14;14(42):6584-8
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  • [Title] Adult T-cell leukemia/lymphoma presenting multiple lymphomatous polyposis.
  • Multiple lymphomatous polyposis (MLP) is an unusual form of non-Hodgkin's lymphoma characterized by polyps throughout the gastrointestinal tract.
  • It has been reported that most MLP are observed in cases with mantle cell lymphoma of B-cell type.
  • The patient died despite combination of chemotherapy.
  • [MeSH-major] Colonic Polyps / etiology. Intestinal Polyposis / etiology. Leukemia-Lymphoma, Adult T-Cell / complications
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols. Colonoscopy. Diagnosis, Differential. Fatal Outcome. Humans. Male. Middle Aged. Treatment Failure

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  • (PMID = 19030219.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] China
  • [Number-of-references] 24
  • [Other-IDs] NLM/ PMC2773353
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8. Ruskoné-Fourmestraux A, Audouin J: Primary gastrointestinal tract mantle cell lymphoma as multiple lymphomatous polyposis. Best Pract Res Clin Gastroenterol; 2010 Feb;24(1):35-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary gastrointestinal tract mantle cell lymphoma as multiple lymphomatous polyposis.
  • Primary gastrointestinal involvement of mantle cell lymphoma (MCL) is rare with a frequency reported between 4 and 9% of all gastrointestinal B-cell non-Hodgkin lymphomas.
  • It was first described and so-called as multiple lymphomatous polyposis (MLP).
  • Its clinical presentation is usually characteristic, with multiple lymphomatous polyps involving several digestive tract segments and a marked tendency towards extra-intestinal spread.
  • The constant and typical phenotypic features of the small cleaved tumour cells, characterised as CD20+, CD5+ CD23- with a t(11;14) (q13;q32) and cyclin D1 overexpression on immunochemistry, allow MLP to be considered as the gastrointestinal counterpart of peripheral nodal MCL.
  • Response to intensive chemotherapy regimens usually results in regression of macroscopic and sometimes microscopic lesions but remissions are short and median survival from 3 to 4 years.
  • Earlier diagnosis with further studies integrating novel agents are still required to determine the optimal treatment with less toxicity.
  • [MeSH-major] Gastrointestinal Neoplasms. Intestinal Polyposis. Lymphoma, Mantle-Cell
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Humans. Stem Cell Transplantation. Transplantation, Autologous. Treatment Outcome

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  • [Copyright] 2010 Elsevier Ltd. All rights reserved.
  • (PMID = 20206107.001).
  • [ISSN] 1532-1916
  • [Journal-full-title] Best practice & research. Clinical gastroenterology
  • [ISO-abbreviation] Best Pract Res Clin Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 46
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9. Isomoto H, Maeda T, Akashi T, Tsuchiya T, Kawaguchi Y, Sawayama Y, Koida S, Ohnita K, Kohno S, Tomonaga M: Multiple lymphomatous polyposis of the colon originating from T-cells: a case report. Dig Liver Dis; 2004 Mar;36(3):218-21
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  • [Title] Multiple lymphomatous polyposis of the colon originating from T-cells: a case report.
  • Multiple lymphomatous polyposis is an unusual form of non-Hodgkin's lymphoma characterised by myriad polyps throughout the alimentary tract.
  • Most multiple lymphomatous polyposis cases are derived from B-cell, and there has been little information on multiple lymphomatous polyposis of T-cell origin.
  • The patient was treated with combined chemotherapy, leading to complete resolution of the lesions.

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  • (PMID = 15046193.001).
  • [ISSN] 1590-8658
  • [Journal-full-title] Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
  • [ISO-abbreviation] Dig Liver Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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10. Karoui S, Kchir N, Jemni F, Khalfallah S, Boubaker J, Boussen H, Zitouna MM, Filali A: [Multiple lymphomatous polyposis of the gastrointestinal tract: a Tunisian case]. Tunis Med; 2004 May;82(5):457-60
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  • [Title] [Multiple lymphomatous polyposis of the gastrointestinal tract: a Tunisian case].
  • [Transliterated title] Polypose lymphomateuse multiple du tube digestif: un cas Tunisien.
  • Multiple lymphomatous polyposis is a distinctive primary gastrointestinal lymphoma which endoscopical, histopathological et immunophenotypical characteristics are well known.
  • We report the case of a 75-year-old male patient with multiple lymphomatous polyposis affecting the rectum, the colon and the stomach associated with an involvement of lymphadenopathies, bone marrow and liver.
  • Treatment by chemotherapy was ineffective and patient dead after 3 sessions of CEOP protocol.

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  • (PMID = 15453049.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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11. Remes-Troche JM, De-Anda J, Ochoa V, Barreto-Zuñiga R, Arista-Nasr J, Valdovinos MA: A rare case of multiple lymphomatous polyposis with widespread involvement of the gastrointestinal tract. Arch Pathol Lab Med; 2003 Aug;127(8):1028-30

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of multiple lymphomatous polyposis with widespread involvement of the gastrointestinal tract.
  • Multiple lymphomatous polyposis (MLP) is an uncommon type of primary non-Hodgkin gastrointestinal (GI) B-cell lymphoma characterized by the presence of multiple polyps along the GI tract.
  • Malignant cells of MLP have mantle cell characteristics and thus are considered to be the counterpart of the mantle cell lymphoma (MCL) in the GI tract.
  • The lymphomatous polyps extended from the esophagus to the rectum, with bone marrow infiltration.
  • The patient was treated with a combined cyclophosphamide, vincristine, and prednisone chemotherapy regimen, resulting in a partial response.
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Humans. Lymphoma, Mantle-Cell / drug therapy. Lymphoma, Mantle-Cell / pathology. Male. Middle Aged

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  • (PMID = 12873180.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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12. D'Antonio A, Boscaino A, Addesso M, Liguori G, Nappi O: Nonpolypoid intestinal mantle cell lymphoma resembling MALT lymphoma with successful response to rituximab. South Med J; 2008 Nov;101(11):1168-9
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  • They involved the ileum and right colon without multiple lymphomatous polyposis and morphologically resembled an extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Immunologic Factors / therapeutic use. Lymphoma, Mantle-Cell / drug therapy. Lymphoma, Mantle-Cell / physiopathology
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Murine-Derived. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Humans. Male. Prednisone / therapeutic use. Rituximab. Vincristine / therapeutic use

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  • (PMID = 19088534.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Immunologic Factors; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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13. Murase K, Matsunaga T, Sato T, Kuribayashi K, Kogawa K, Kawano Y, Okamoto T, Takayama T, Watanabe H, Niitsu Y, Hirayama Y: Allogeneic bone marrow transplantation in a patient with T-prolymphocytic leukemia with small-intestinal involvement. Int J Clin Oncol; 2003 Dec;8(6):391-4
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  • [Title] Allogeneic bone marrow transplantation in a patient with T-prolymphocytic leukemia with small-intestinal involvement.
  • We performed an unrelated allogeneic bone marrow transplantation in a patient with T-PLL who had multiple lymphomatous polyposis of the small intestine refractory to combination chemotherapy (cyclophosphamide, vincristine, and prednisolone [COP] and fludarabine plus cyclophosphamide).
  • The patient developed no graft-versus-host disease (GVHD) and remains in complete remission 16 months after the transplantation.
  • T-PLL is usually refractory to chemotherapy and is a T-cell malignancy with poor prognosis.
  • It is suggested that allo-HSCT may improve the prognosis in patients with T-PLL involving the small intestine.
  • [MeSH-major] Bone Marrow Transplantation. Intestinal Polyposis / etiology. Leukemia, Prolymphocytic / complications. Leukemia, Prolymphocytic / therapy. Leukemia, T-Cell / complications. Leukemia, T-Cell / therapy. Vidarabine / analogs & derivatives
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / administration & dosage. Drug Resistance, Neoplasm. Humans. Male. Prednisone / administration & dosage. Transplantation, Homologous. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 14663643.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; FA2DM6879K / Vidarabine; P2K93U8740 / fludarabine; VB0R961HZT / Prednisone; COP protocol 2
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14. Iwamuro M, Okada H, Takenaka R, Kawahara Y, Shinagawa K, Morito T, Ichimura K, Yoshino T, Yamamoto K: [Nine cases of mantle cell lymphoma with gastrointestinal involvement]. Nihon Shokakibyo Gakkai Zasshi; 2009 Apr;106(4):520-8
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  • Nine cases of mantle cell lymphoma with gastrointestinal involvement were retrospectively reviewed, and their clinical features, including the involved organs, macroscopic forms, treatment methods, and prognoses were evaluated.
  • The macroscopic form of the gastric involvement varied, and included the protruding type in 3 cases, the ulcerated type in one, and the superficial type in one.
  • On the other hand, the macroscopic form of the intestinal involvement from the duodenum to the rectum was mostly of the multiple lymphomatous polyposis type, which was observed in 6 cases.
  • A hyper CVAD/MA regimen and high-dose chemotherapy with autologous peripheral blood stem cell transplantation was performed in 5 cases.

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  • (PMID = 19346720.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 33
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15. Huang WT, Hsu YH, Yang SF, Chuang SS: Primary gastrointestinal follicular lymphoma: a clinicopathologic study of 13 cases from Taiwan. J Clin Gastroenterol; 2008 Oct;42(9):997-1002
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: There were 5 men and 8 women with a median age of 58 years (range, 31 to 74; mean, 55).
  • Multiple lymphomatous polyposis was present in 6 patients (46%).
  • Treatment included surgery with or without chemotherapy.
  • At a median follow-up time of 51 months (range, 3 to 180; mean, 63), 11 patients (85%) were disease free and no patient died of lymphoma.
  • These tumors frequently involved ileum with a favorable prognosis.

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  • (PMID = 18719510.001).
  • [ISSN] 1539-2031
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Ruskoné-Fourmestraux A: Gastrointestinal lymphomas: the French experience of the Groupe D'etude des Lymphomes Digestifs (GELD). Recent Results Cancer Res; 2000;156:99-103
MedlinePlus Health Information. consumer health - Lymphoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastrointestinal lymphomas: the French experience of the Groupe D'etude des Lymphomes Digestifs (GELD).
  • Since 1983, the French Groupe d'Etude des Lymphomes Digestifs (GELD), under the aegis of the Fondation Française de Cancérologie Digestive, has aimed to identify the different prognostic groups of the primary digestive-tract lymphomas (PDTL) and their optimal treatment.
  • A marked improvement in their prognosis was obtained by a strategy including precise histologic typing and clinical staging followed by a therapeutic approach combining initial surgical resection, whenever possible or reasonable, followed by chemotherapy adapted to the grade of malignancy and resectability of the lymphoma.
  • However, Helicobacter pylori eradication should be the first treatment in stage IE low-grade gastric mucosa-associated lymphoid tissue (MALT) tumors.
  • The long-term results of such medical treatment are evaluated together with the management and the place of surgery in these localised tumors.
  • Thirty-one cases of multiple lymphomatous polyposis were also collected and confirmed to be a distinct entity among PDTL and the gastrointestinal counterpart of the mantle-cell-zone lymphomas.
  • High-dose radio-chemotherapy supported by auto-transplantation improved their prognosis.
  • [MeSH-minor] Adolescent. Adult. Aged. Combined Modality Therapy. Humans. Middle Aged

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  • (PMID = 10802868.001).
  • [ISSN] 0080-0015
  • [Journal-full-title] Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer
  • [ISO-abbreviation] Recent Results Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] GERMANY
  • [Number-of-references] 7
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17. Nakamura S, Matsumoto T, Iida M: [Malignant lymphoma of the small intestine]. Nihon Rinsho; 2008 Jul;66(7):1297-302
MedlinePlus Health Information. consumer health - Lymphoma.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant lymphoma of the small intestine].
  • The clinicopathologic features of malignant lymphoma of the small intestine were reviewed.
  • Macroscopically, small intestinal lymphomas are classified as polypoid, ulcerative (including stricturing, non-stricturing and aneurysmal forms on radiography), multiple lymphomatous polyposis, diffuse, or other types.
  • A significant correlation is observed between these macroscopic/radiographic and histologic types.
  • The therapeutic strategy, such as surgery, chemotherapy, antibiotics or watch-and-wait, should be determined based on the disease extent, histologic type, and clinical stage.

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  • (PMID = 18616120.001).
  • [ISSN] 0047-1852
  • [Journal-full-title] Nihon rinsho. Japanese journal of clinical medicine
  • [ISO-abbreviation] Nippon Rinsho
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 13
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18. Tamura S, Ohkawauchi K, Yokoyama Y, Higashidani Y, Daibata M, Hiroi M, Yamamori S, Onishi S: Non-multiple lymphomatous polyposis form of mantle cell lymphoma in the gastrointestinal tract. J Gastroenterol; 2004 Oct;39(10):995-1000
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Non-multiple lymphomatous polyposis form of mantle cell lymphoma in the gastrointestinal tract.
  • Multiple lymphomatous polyposis (MLP) is an uncommon disease that is regarded as the intestinal form of MCL.
  • We present a rare case of gastrointestinal MCL without MLP, and demonstrate that rituximab was effective for the treatment of this patient.
  • For treatment, the patient received a total of ten courses of combination chemotherapy consisting of cyclophosphamide (1000 mg), doxorubicin (70 mg), vincristine (2 mg) and prednisolone (50 mg) (CHOP), which led to a partial remission.
  • As the infiltrating lymphoma cells expressed CD20 molecules on their surfaces, the patient was treated with a chimeric anti-CD20 monoclohal antibody, rituximab, which showed significant efficacy, and a second partial remission was achieved.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Gastrointestinal Neoplasms / drug therapy. Lymphoma, Mantle-Cell / drug therapy. Prednisolone / therapeutic use. Vincristine / therapeutic use
  • [MeSH-minor] Antibodies, Monoclonal / therapeutic use. Antibodies, Monoclonal, Murine-Derived. Antineoplastic Agents / therapeutic use. Colonoscopy. Endoscopy, Gastrointestinal. Humans. Immunohistochemistry. Male. Middle Aged. Polymerase Chain Reaction. Remission Induction. Rituximab. Translocation, Genetic

  • Genetic Alliance. consumer health - Mantle cell lymphoma.
  • Hazardous Substances Data Bank. RITUXIMAB .
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  • [CommentIn] J Gastroenterol. 2004 Oct;39(10):1023-4 [15549463.001]
  • (PMID = 15549454.001).
  • [ISSN] 0944-1174
  • [Journal-full-title] Journal of gastroenterology
  • [ISO-abbreviation] J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Antineoplastic Agents; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VAP-cyclo protocol
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19. Michopoulos S, Petraki K, Matsouka C, Kastritis E, Chrysanthopoulou H, Dimopoulos MA: Mantle-cell lymphoma (multiple lymphomatous polyposis) of the entire GI tract. J Clin Oncol; 2008 Mar 20;26(9):1555-7
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mantle-cell lymphoma (multiple lymphomatous polyposis) of the entire GI tract.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Gastrointestinal Neoplasms / diagnosis. Gastrointestinal Neoplasms / drug therapy. Lymphoma, Mantle-Cell / diagnosis. Lymphoma, Mantle-Cell / drug therapy
  • [MeSH-minor] Aged. Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Murine-Derived. Boronic Acids / administration & dosage. Bortezomib. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Gastrointestinal Hemorrhage / etiology. Humans. Immunohistochemistry. Male. Prednisone / administration & dosage. Prognosis. Pyrazines / administration & dosage. Rituximab. Severity of Illness Index. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 18349408.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Boronic Acids; 0 / Pyrazines; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 69G8BD63PP / Bortezomib; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone
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20. Mukogawa T, Fujii H, Koyama F, Matsumoto H, Kojima Y, Takeuchi T, Yagi H, Arai M, Nakajima Y: [Anti-CD20 antibody and combination chemotherapy followed by autologous peripheral blood stem cell transplantation after high-dose chemotherapy induced complete remission in a case of multiple lymphomatous polyposis of the gastrointestinal tract]. Nihon Shokakibyo Gakkai Zasshi; 2003 Dec;100(12):1382-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Anti-CD20 antibody and combination chemotherapy followed by autologous peripheral blood stem cell transplantation after high-dose chemotherapy induced complete remission in a case of multiple lymphomatous polyposis of the gastrointestinal tract].
  • [MeSH-major] Antibodies, Monoclonal / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Intestinal Neoplasms / therapy. Intestinal Polyposis / therapy. Lymphoma, Mantle-Cell / therapy. Peripheral Blood Stem Cell Transplantation
  • [MeSH-minor] Antibodies, Monoclonal, Murine-Derived. Cyclophosphamide / administration & dosage. Cytarabine / administration & dosage. Dexamethasone / administration & dosage. Drug Administration Schedule. Etoposide / administration & dosage. Humans. Male. Middle Aged. Remission Induction. Rituximab

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  • (PMID = 14748324.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 04079A1RDZ / Cytarabine; 4F4X42SYQ6 / Rituximab; 6PLQ3CP4P3 / Etoposide; 7S5I7G3JQL / Dexamethasone; 8N3DW7272P / Cyclophosphamide; CHASE protocol
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