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Items 1 to 27 of about 27
1. Matoba-Ueno K, Fujimoto S, Doi N, Nishino T, Yamano S, Shiiki H, Hashimoto T, Nakamura S: [CHF arising after low dose THP-COP chemotherapy in an elderly patient with malignant lymphoma]. Nihon Ronen Igakkai Zasshi; 2001 Jul;38(4):548-53
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  • [Title] [CHF arising after low dose THP-COP chemotherapy in an elderly patient with malignant lymphoma].
  • A 76-year-old woman was admitted with a one-month history of low grade fever and dizziness.
  • A specimen from the right supraclavicular lymph node showed malignant lymphoma (diffuse large B cell type).
  • We started chemotherapy according to the low-dose THP-COP protocol (pirarubicin, cyclophosphamide, vincristine and prednisolone) on the 31st hospital day.
  • In this case, congestive heart failure developed even though the total dose of pirarubicin was lower than in previous reports of this complication.
  • [MeSH-major] Antibiotics, Antineoplastic / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Doxorubicin / adverse effects. Heart Failure / chemically induced. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy

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  • (PMID = 11523171.001).
  • [ISSN] 0300-9173
  • [Journal-full-title] Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics
  • [ISO-abbreviation] Nihon Ronen Igakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; D58G680W0G / pirarubicin; VEP-THP protocol
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2. Fujita Y, Ikebuchi M, Tarui S, Irie H: Successful combined treatment of primary cardiac malignant lymphoma with urgent cardiac operation and chemotherapy. Circ J; 2009 May;73(5):967-9
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  • [Title] Successful combined treatment of primary cardiac malignant lymphoma with urgent cardiac operation and chemotherapy.
  • A 56-year-old man, suffering from rapidly worsening general fatigue, dyspnea on exercise and epigastralgia, was referred for evaluation and treatment of a cardiac tumor.
  • Lymphoma was highly suggested.
  • Pathological examination suggested malignant lymphoma, diffuse large B-cell type.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cardiac Surgical Procedures. Heart Neoplasms / drug therapy. Heart Neoplasms / surgery. Lymphoma, Large B-Cell, Diffuse / drug therapy. Lymphoma, Large B-Cell, Diffuse / surgery
  • [MeSH-minor] Antibodies, Monoclonal / administration & dosage. Antibodies, Monoclonal, Murine-Derived. Chemotherapy, Adjuvant. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Heart Failure / drug therapy. Heart Failure / etiology. Heart Failure / surgery. Humans. Male. Middle Aged. Prednisone / administration & dosage. Rituximab. Tomography, X-Ray Computed. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 19088397.001).
  • [ISSN] 1346-9843
  • [Journal-full-title] Circulation journal : official journal of the Japanese Circulation Society
  • [ISO-abbreviation] Circ. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone
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3. Tanaka M, Matsuzaki J, Kitami K, Hirokawa M: [A case of primary malignant lymphoma of the pararectal space]. Hinyokika Kiyo; 2002 Sep;48(9):561-4
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  • [Title] [A case of primary malignant lymphoma of the pararectal space].
  • Histopathological diagnosis was non-Hodgkin's malignant lymphoma (diffuse large B-cell type according to the new WHO classification).
  • The results of some examinations were compatible with the diagnosis of primary lymphoma of the pararectal space.
  • The patient underwent 2 courses of combination chemotherapy CHOP (consisting of cyclophosphamide, doxorubichin, vincristine, and prednisolone), and high-dose chemotherapy (ranimustine, etoposide, ifosfamide) with peripheral blood stem cell transplantation.
  • After high-dose chemotherapy, radiation therapy was performed since there was a possibility of residual tumor, and complete remission was achieved.
  • This is probably the first clinical case of malignant lymphoma of the pararectal space ever reported in the Japanese literature.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymphoma, B-Cell / therapy. Lymphoma, Large B-Cell, Diffuse / therapy. Peripheral Blood Stem Cell Transplantation. Rectal Neoplasms / therapy
  • [MeSH-minor] Adolescent. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Drug Administration Schedule. Humans. Male. Prednisone / administration & dosage. Vincristine / administration & dosage

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  • (PMID = 12402484.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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4. Watanabe N, Sugimoto N, Matsushita A, Maeda A, Nagai K, Hanioka K, Takahashi T: Association of intestinal malignant lymphoma and ulcerative colitis. Intern Med; 2003 Dec;42(12):1183-7
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  • [Title] Association of intestinal malignant lymphoma and ulcerative colitis.
  • A 42-year-old woman with refractory ulcerative colitis (UC) developed ascites, pleural effusion, pretibial edema and severe anemia.
  • Colonofiberscopic examination showed a bulky submucosal tumor in the sigmoid colon, which was histologically diagnosed as malignant lymphoma (diffuse large, B cell type).
  • The lymphoma was resistant to chemotherapy.
  • Although the association of intestinal lymphoma with UC is rare, lymphoma should be taken into consideration when the clinical course of UC is atypical or when UC is refractory to therapy.
  • [MeSH-major] Colitis, Ulcerative / complications. Lymphoma / complications. Sigmoid Neoplasms / complications
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / therapeutic use. Colonoscopy. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Etoposide / therapeutic use. Fatal Outcome. Female. Humans. Ifosfamide / therapeutic use. Methotrexate / therapeutic use. Peripheral Blood Stem Cell Transplantation. Vincristine / therapeutic use

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  • (PMID = 14714955.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; UM20QQM95Y / Ifosfamide; YL5FZ2Y5U1 / Methotrexate; CAMBO-VIP protocol
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5. Hamada S, Ito K, Kanbara T, Yoshii T, Sato K, Sumitomo M, Kimura F, Asano T: [A case of malignant lymphoma mimicking a seminal vesicle tumor]. Hinyokika Kiyo; 2010 Jul;56(7):393-6

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  • [Title] [A case of malignant lymphoma mimicking a seminal vesicle tumor].
  • Abdominal computed tomography (CT) showed a mass 7 cm in diameter mimicking a seminal vesicle tumor and magnetic resonance imaging showed a heterogeneously enhanced mass with an unclear borderline to the rectum.
  • Transrectal needle biopsy revealed non-Hodgkin's malignant lymphoma (diffuse large B cell lymphoma).
  • Chest and abdominal CT showed no specific findings except the lesion for the seminal vesicle lesion, but positron emission tomography showed accumulations in the gastrointestinal tract, pleura, and lymph nodes.
  • The patient was thus determined to have stage IV malignant lymphoma and was given two courses of combination chemotherapy including RCHOP.
  • [MeSH-major] Genital Neoplasms, Male / diagnosis. Lymphoma, Large B-Cell, Diffuse / diagnosis. Seminal Vesicles

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  • (PMID = 20724815.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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6. Suzuki T, Koga H, Yamazaki S, Saeki H, Tanaka H, Nishimura M, Nakaseko C, Nakasa H, Nakamura H, Ariyoshi N, Kitada M: Probable interaction between warfarin and antitumor agents used in R-ESHAP chemotherapy. Clin Ther; 2008 Jun;30(6):1155-9
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  • [Title] Probable interaction between warfarin and antitumor agents used in R-ESHAP chemotherapy.
  • BACKGROUND: The pharmacologic effects of warfarin might be altered by various factors, including drug-drug interaction.
  • CASE SUMMARY: A 49-year-old Japanese man (height, 174 cm; weight, 68 kg) presented with a 20-month history of malignant lymphoma (diffuse large B cell lymphoma, clinical stage IV).
  • He was treated with a combination of rituximab chemotherapy and etoposide, cisplatin, high-dose cytarabine, and methyl-prednisolone (R-ESHAP).
  • The INR was increased from 2.44 to 4.71 during chemotherapy but was returned to within the normal range (1.05; normal range: 0.81-1.009) 5 days after chemotherapy was completed.
  • CONCLUSION: In this patient, R-ESHAP chemotherapy might have affected warfarin anticoagulation sensitivity; thus, careful monitoring of INR is essential, particularly in patients receiving warfarin who undergo R-ESHAP chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymphoma, Large B-Cell, Diffuse / drug therapy. Venous Thrombosis / drug therapy. Warfarin / therapeutic use
  • [MeSH-minor] Cisplatin / therapeutic use. Cytarabine / therapeutic use. Drug Interactions. Etoposide / therapeutic use. Follow-Up Studies. Humans. Male. Methylprednisolone / therapeutic use. Middle Aged. Pulmonary Embolism / etiology. Pulmonary Embolism / prevention & control

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  • (PMID = 18640471.001).
  • [ISSN] 0149-2918
  • [Journal-full-title] Clinical therapeutics
  • [ISO-abbreviation] Clin Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 5Q7ZVV76EI / Warfarin; 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin; X4W7ZR7023 / Methylprednisolone; ESAP protocol
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7. Yoshino S, Nakamura S, Matsumoto T, Konomi H, Hirahashi M, Yao T, Iida M: [A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy]. Nihon Shokakibyo Gakkai Zasshi; 2006 Feb;103(2):162-7
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  • [Title] [A case of primary gastric malignant lymphoma perforated immediately after administration of chemotherapy].
  • We diagnosed gastric malignant lymphoma, diffuse large B-cell type and determined stage IV according to the Lugano International Conference classification.
  • Due to gastric perforation occurred on day 4 of chemotherapy, total gastrectomy and partial resection of the transverse colon were performed.
  • Complete remission was achieved by 2 cycles of postoperative chemotherapy together with rituximab.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Lymphoma, B-Cell / complications. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / complications. Lymphoma, Large B-Cell, Diffuse / drug therapy. Stomach Diseases / chemically induced. Stomach Neoplasms / complications. Stomach Neoplasms / drug therapy

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  • (PMID = 16506664.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VEP-THP protocol
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8. Okumoto T, Tomiyama K, Ino H, Kanaya Y, Maruyama S, Otani J, Yokoyama N, Soda M: [A case of malignant lymphoma of the stomach in which preoperative chemotherapy provided a complete response]. Gan To Kagaku Ryoho; 2002 Jun;29(6):943-7
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  • [Title] [A case of malignant lymphoma of the stomach in which preoperative chemotherapy provided a complete response].
  • We have encountered a case of malignant lymphoma of the stomach in which a complete remission was confirmed in a resected specimen after chemotherapy.
  • A biopsy from gastric endoscopy indicated malignant lymphoma of diffuse large B-cell type.
  • The patient was assumed to be inoperable due to enlargement of the tumor and lymph node metastasis, and THP-COP chemotherapy was carried out.
  • Total gastrectomy and splenectomy with lymph node dissection (D2) were performed after chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy. Prednisolone / therapeutic use. Stomach Neoplasms / drug therapy. Vincristine / therapeutic use

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  • (PMID = 12090049.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VEP-THP protocol
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9. Kawakami K, Watanabe Y, Kadowaki S: [Therapy-related acute myelogenous leukemia (AML-M6) with add(11) (q23) and del(20) (q11.2) developing via myelodysplastic syndrome after chemotherapy for malignant lymphoma]. Rinsho Ketsueki; 2003 Mar;44(3):168-73
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  • [Title] [Therapy-related acute myelogenous leukemia (AML-M6) with add(11) (q23) and del(20) (q11.2) developing via myelodysplastic syndrome after chemotherapy for malignant lymphoma].
  • A 62-year-old woman was diagnosed as having malignant lymphoma, diffuse large B-cell type.
  • She underwent chemotherapy with the standard dose of CHOP and MINE regimens, resulting in complete remission.
  • Four months later, the myelodysplastic syndrome of RA (refractory anemia) with pancytopenia developed and rapidly progressed to acute myelogenous leukemia (AML-M6) in 4 months.
  • The autopsy showed no residual disease of lymphoma-related disease.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Chromosome Aberrations. Leukemia, Erythroblastic, Acute / etiology. Leukemia, Erythroblastic, Acute / genetics. Myelodysplastic Syndromes / etiology. Neoplasms, Second Primary / etiology
  • [MeSH-minor] Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 5. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Etoposide / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy. Middle Aged. Mitoguazone / administration & dosage. Prednisolone / administration & dosage. Vinblastine / administration & dosage. Vinblastine / analogs & derivatives. Vincristine / administration & dosage


10. Hiramoto K, Kuroki M, Shoji H, Matsumura Y, Miura A, Kikuchi Y, Hirakawa H, Kimura J, Matsuda M: [A case of primary hepato-biliary malignant lymphoma effectively treated with R-CHOP chemotherapy]. Gan To Kagaku Ryoho; 2010 Jul;37(7):1345-8
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  • [Title] [A case of primary hepato-biliary malignant lymphoma effectively treated with R-CHOP chemotherapy].
  • The specimens obtained with ultrasound-guided needle biopsy showed malignant lymphoma (diffuse large B-cell lymphoma: DLBCL).
  • CHOP with Rituximab therapy (R-CHOP therapy) was performed.
  • The treatment resulted in remarkable reduction of the tumor size and improvement of the biliary stenosis.
  • We should take into consideration malignant lymphoma when we see a patient with a tumor of the hepato-biliary system.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bile Duct Neoplasms / drug therapy. Liver Neoplasms / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy
  • [MeSH-minor] Aged. Antibodies, Monoclonal, Murine-Derived. Biopsy, Needle. Cyclophosphamide / administration & dosage. Cyclophosphamide / therapeutic use. Doxorubicin / administration & dosage. Doxorubicin / therapeutic use. Humans. Magnetic Resonance Imaging. Male. Prednisone / administration & dosage. Prednisone / therapeutic use. Rituximab. Tomography, X-Ray Computed. Vincristine / administration & dosage. Vincristine / therapeutic use

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  • (PMID = 20647724.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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11. Bolanowski M, Kuliszkiewicz-Janus M, Sokolska V: Diffuse malignant lymphoma type B with optic chiasm infiltration, visual disturbances, hypopituitarism, hyperprolactinaemia and diabetes insipidus. Case report and literature review. Endokrynol Pol; 2006 Nov-Dec;57(6):642-7
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  • [Title] Diffuse malignant lymphoma type B with optic chiasm infiltration, visual disturbances, hypopituitarism, hyperprolactinaemia and diabetes insipidus. Case report and literature review.
  • The case is reported of a 55-year-old man with diffuse malignant lymphoma type B associated with transient optic chiasm infiltration and visual disturbances but with persistent hypopituitarism, hyperprolactinaemia and diabetes insipidus.
  • The patient was administered chemotherapy and radiotherapy.
  • Repeated MR and CT scans showed optic chiasm infiltration, which disappeared in the course of the chemotherapy but then recurred, changed its appearance and finally disappeared again.
  • In the meantime visual disturbances occurred and disappeared during the therapy.
  • Hypopituitarism, diabetes insipidus and hyperprolactinaemia were diagnosed and replacement therapy was administered.
  • These were diffuse malignant lymphoma with regional lymphonodulitis in histology.
  • The length of survival time documented following the hypothalamochiasmatic infiltration and diagnosis of lymphoma makes the case an unusual one for patients with CNS lymphoma.
  • [MeSH-major] Lymphoma, Non-Hodgkin / complications

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  • (PMID = 17253438.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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12. Cavalot AL, Preti G, Vione N, Nazionale G, Palonta F, Fadda GL: Isolated primary non-Hodgkin's malignant lymphoma of the larynx. J Laryngol Otol; 2001 Apr;115(4):324-6
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  • [Title] Isolated primary non-Hodgkin's malignant lymphoma of the larynx.
  • We report a case of glottic primary laryngeal lymphoma.
  • Microscopic study showed a diffuse malignant lymphoma of high-grade malignancy (WF sub-division H).
  • A diffuse, large, B-cell-type NHL was diagnosed histopathologically.
  • The patient was treated with combination chemotherapy, including cyclophosphamide, doxorubicin, vincristine and prednisolone (CHOP), which resulted in complete clinical remission after two courses.
  • Four courses of combination chemotherapy were subsequently performed, making a total of six courses of combination chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Laryngeal Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy. Lymphoma, Non-Hodgkin / drug therapy
  • [MeSH-minor] Aged. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Humans. Male. Prednisolone / therapeutic use. Treatment Outcome. Vincristine / therapeutic use

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  • (PMID = 11276342.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone
  • [Number-of-references] 28
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13. Yachida S, Sasako M, Tobinai K, Matsuno Y, Shimoda T: Successful treatment of a primary gastric T-cell lymphoma lacking the human T-cell leukemia virus type 1. Hepatogastroenterology; 2010 Mar-Apr;57(98):383-7
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  • [Title] Successful treatment of a primary gastric T-cell lymphoma lacking the human T-cell leukemia virus type 1.
  • Among the previously reported cases of exceptional primary gastric T-cell lymphomas, most demonstrate evidence of human T-cell leukemia virus type 1 (HTLV-1) infection with a poor prognosis.
  • The present study is a report of a rare case of primary gastric T-cell lymphoma without HTLV-1 which could be successfully treated with surgical resection and adjuvant chemotherapy.
  • Radiographic and endoscopic examinations revealed an ill-demarcated ulcerative lesion in the stomach, and a biopsy specimen confirmed high-grade lymphoma.
  • Histological examination of the gastric lesion revealed a malignant lymphoma, diffuse large cell type, with lymph nodal involvement.
  • On immunohistochemistry, tumor cells were positive for CD3, CD4 and CD30, but negative for CD8, CD20 and CD56, implying a T-cell nature.
  • Following surgery, the patient received 8 cycles of chemotherapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone/CHOP).
  • To date the patient has been free of recurrence for 86 months without further treatment.
  • Review of previously reported cases of primary gastric T-cell lymphoma indicates that the prognosis is better without than with HTLV-1.
  • We conclude that primary gastric T-cell lymphomas without HTLV-1 should be managed in the same way as the more common diffuse large B-cell type gastric lymphomas.
  • [MeSH-major] Lymphoma, T-Cell / drug therapy. Lymphoma, T-Cell / surgery. Stomach Neoplasms / drug therapy. Stomach Neoplasms / surgery
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Combined Modality Therapy. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Gastrectomy. Human T-lymphotropic virus 1. Humans. Lymph Node Excision. Male. Middle Aged. Prednisone / therapeutic use. Vincristine / therapeutic use

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  • (PMID = 20583449.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
  • [Number-of-references] 25
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14. Krásný J, Sach J, Brunnerová R, Konvicka J, Jankovská M, Srp A, Kozák J: [Orbital tumors in adults--a 10-year study]. Cesk Slov Oftalmol; 2008 Nov;64(6):219-27

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  • The authors refer about diagnostic procedures, treatment and follow-up of 87 adult patients with orbital tumors during the period 1998 - 2007 in the Department of Ophthalmology, Faculty Hospital Královské Vinohrady, Charles University, Prague, Czech Republic, E.U.
  • In 49 patients, the tumors were of benign origin (age 18-80 years, median, 48 years), and 38 patients suffered from malign tumors (age 38-89 years, median, 61 years).
  • The anterior diagnostic or therapeutic orbitotomy was used in 72.5% of the cases, lateral osteoplastic orbitotomy (Kronlein) in 14.5%, and exenteration of the orbit in 13% of the cases.
  • Clinically they were of the anterior nodular, or posterior diffuse form, dacryoadenitis or orbital myositis.
  • All patients were treated by means of prednisolon for at least three months; due to the relapse of the immunopathologic process, in 16 % of the cases the therapy was supplemented with azathioprime.
  • The surgical procedure was the choice of treatment in 66% of inflammatory processes in the lacrimal gland region.
  • In four cases the sarcoidosis was established.The second tumor in the final ranking was lymphoma in 19.5%; the MALT-lymphoma was diagnosed in 59% of these cases.
  • The chemotherapy was chosen for the treatment in 2/3 of the cases, and in all cases the remission was reached.The actinotherapy was chosen especially in other types of lymphoma; the follicular form and "molding" lymphoma were the causes of the death in two patients.
  • Among malignant tumors, the most serious clinical courses were histological different primary carcinomas of the orbitopalpebral region in 14% of the cases, and secondary melanoma spreading from the conjunctiva in 5.5%.
  • CONCLUSION: Among orbital tumors in adults, the most common were inflammatory pseudotumor and lymphoma.
  • The decisive procedure was always the histological verification, which directed the following therapy.

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  • (PMID = 19110961.001).
  • [ISSN] 1211-9059
  • [Journal-full-title] Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti
  • [ISO-abbreviation] Cesk Slov Oftalmol
  • [Language] cze
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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15. Epure C, Ionascu L, Hagima N, Nan S, Stefaniu I: [Malignant non-Hodgkin diffuse lymphoma with extranodal orbital involvement--a clinical case]. Oftalmologia; 2005;49(4):29-32
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  • [Title] [Malignant non-Hodgkin diffuse lymphoma with extranodal orbital involvement--a clinical case].
  • [Transliterated title] Limfom malign nonhodgkinian difuz, cu afectare extraganglionară oculară--caz clinic.
  • The subsequent evolution of the disease required extensive investigations which provide the definitive diagnosis of non-Hodgkin, diffuse B-cell lymphoma, with extranodal orbital involvement.
  • In this case, the treatment of choice it must be systemic chemotherapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymphoma, B-Cell / diagnosis. Lymphoma, Non-Hodgkin / diagnosis. Orbital Neoplasms / diagnosis
  • [MeSH-minor] Cyclophosphamide / administration & dosage. Diagnosis, Differential. Female. Humans. Middle Aged. Prednisone / administration & dosage. Treatment Outcome

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  • (PMID = 16524121.001).
  • [ISSN] 1220-0875
  • [Journal-full-title] Oftalmologia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Oftalmologia
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  • [Chemical-registry-number] 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone
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16. Ogawa T, Mizutani M, Yabana T, Miyahara S, Murabayashi K: A Case of Burkitt's Lymphoma Involving Both Breasts. Breast Cancer; 2005;12(3):234-7
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  • [Title] A Case of Burkitt's Lymphoma Involving Both Breasts.
  • Primary malignant lymphoma of the breast is rare, and Burkitt's lymphoma is especially rare.
  • We report the case of a 44-year-old woman in whom Burkitt's lymphoma involving both breasts was diagnosed.
  • The patient was referred to our hospital because of a diffuse, firm swelling, like a bulky ball, in both breasts.
  • Fine-needle aspiration cytology (FNAC) of both breast masses revealed malignant lymphoma(ML), and diffuse large B-cell lymphoma was diagnosed based on the results of immunohistochemical studies of a core needle biopsy specimen.
  • We instituted initial therapy, with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) plus intrathecal chemotherapy without performing a chromosome analysis, because the clinical course was very aggressive.
  • A CR was achieved, but after eight cycles of CHOP therapy, the ML relapsed.
  • We then resected the mass in the left breast, and when examination of the surgical specimen revealed relapse of ML and t (8;11) (q24;q32) translocation, Burkitt's lymphoma was diagnosed.
  • High-dose chemotherapy followed by peripheral-blood stem cell transplantation was performed, but the patient died 10 months after her initial presentation at our hospital.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Breast Neoplasms / diagnosis. Burkitt Lymphoma / diagnosis. Diagnostic Errors
  • [MeSH-minor] Adult. Cyclophosphamide / therapeutic use. Cytarabine / therapeutic use. Dexamethasone / therapeutic use. Doxorubicin / therapeutic use. Etoposide / therapeutic use. Fatal Outcome. Female. Humans. Lymphoma, B-Cell / diagnosis. Lymphoma, B-Cell / therapy. Peripheral Blood Stem Cell Transplantation. Prednisone / therapeutic use. Vincristine / therapeutic use

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  • (PMID = 16110296.001).
  • [ISSN] 1340-6868
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 04079A1RDZ / Cytarabine; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 7S5I7G3JQL / Dexamethasone; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHASE protocol; CHOP protocol
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17. Toyota S, Nakamura N, Dan K: [Coexistence of pure red cell aplasia and autoimmune hemolytic anemia occurring during remission of malignant lymphoma]. Rinsho Ketsueki; 2002 Jun;43(6):493-5
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  • [Title] [Coexistence of pure red cell aplasia and autoimmune hemolytic anemia occurring during remission of malignant lymphoma].
  • A diagnosis of malignant lymphoma (ML) (diffuse mixed, B-cell type) had been made in March 2000 whereafter she had been treated with CHOP chemotherapy and had achieved complete remission (CR).
  • On examination, it was found she had concurrently developed pure red cell aplasia (PRCA) and warm type autoimmune hemolytic anemia (AIHA) without relapse of the ML.
  • [MeSH-major] Anemia, Hemolytic, Autoimmune / etiology. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lymphoma, B-Cell / complications. Lymphoma, Non-Hodgkin / complications. Red-Cell Aplasia, Pure / etiology

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  • (PMID = 12134708.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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18. Iguchi T, Miyazawa K, Okabe S, Kawakubo K, Shimamoto T, Kuriyama Y, Ito Y, Kimura Y, Ohyashiki K, Serizawa H, Iwaya K, Mukai K: [Relapse of diffuse large B cell lymphoma to CD20-negative multiple cutaneous tumors immediately after anti-CD20 monoclonal antibody (rituximab) therapy]. Rinsho Ketsueki; 2004 Oct;45(10):1129-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Relapse of diffuse large B cell lymphoma to CD20-negative multiple cutaneous tumors immediately after anti-CD20 monoclonal antibody (rituximab) therapy].
  • The pathological findings of the cervical lymph nodes revealed that the patient had a malignant lymphoma, of the diffuse large B cell type, at clinical stage IIIB.
  • Immunohistochemistry demonstrated that the lymphoma cells were positive for CD11a, CD19, CD20, CD23, CD25, CD45, IgM, IgD and lambda, but negative for CD5.
  • Although a complete remission was obtained after 8 courses of CHOP therapy, the patient relapsed 32 months later.
  • Two courses of a half dose of CHASE therapy consisting of CPM, ara-C, VP-16 and dexamethasone, followed by rituximab (600 mg/week x4) resulted in a transient re-induction of complete remission.
  • However, multiple cutaneous tumors became apparent just 10 days after the last rituximab therapy.
  • Immunohistochemistry of the cutaneous tumors revealed infiltration of CD20-negative lymphoma cells.
  • A series of chemotherapy including high-dose MTX was ineffective, and the patient died in August 2003.
  • Autopsy findings revealed the systemic intra-capillary infiltration of CD20 negative-lymphoma cells into multiple organs, including the lungs, liver, and kidneys.
  • A CD20 negative-clone selected by rituximab therapy appeared to have expanded in this case.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antigens, CD20 / immunology. Antineoplastic Agents / therapeutic use. Head and Neck Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy. Lymphoma, Large B-Cell, Diffuse / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Antibodies, Monoclonal, Murine-Derived. Capillaries / pathology. Fatal Outcome. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasms, Vascular Tissue / pathology. Remission Induction. Rituximab


19. Asagi A, Miyake Y, Ando M, Yasuhara H, Matsumoto K, Takahara M, Kawai D, Kaji E, Toyokawa T, Onishi T, Miyatani K, Nakatsu M: [Case of primary malignant lymphoma of the liver treated by R-CHOP therapy]. Nihon Shokakibyo Gakkai Zasshi; 2009 Mar;106(3):389-96
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  • [Title] [Case of primary malignant lymphoma of the liver treated by R-CHOP therapy].
  • Computed tomography (CT) revealed a large tumor in the right lobe of the liver.
  • Needle biopsy specimens showed malignant lymphoma (Diffuse large B cell lymphoma).
  • Ga scintigraphy and FDG-PET did not demonstrate other lesions and the definitive diagnosis was primary malignant lymphoma of the liver.
  • CHOP with Rituximab therapy (R-CHOP therapy) was performed.
  • After 8 courses of therapy the FDG-PET results were negative and we considered complete remission.
  • We describe a case of primary malignant lymphoma of the liver treated successfully by R-CHOP therapy.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Liver Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy. Lymphoma, Large B-Cell, Diffuse / drug therapy

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  • (PMID = 19262053.001).
  • [ISSN] 0446-6586
  • [Journal-full-title] Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology
  • [ISO-abbreviation] Nihon Shokakibyo Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 4F4X42SYQ6 / Rituximab; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; VAP-cyclo protocol
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20. Koike H, Morita T, Tamura Y: [Primary malignant lymphoma of the urinary bladder: a case report]. Nihon Hinyokika Gakkai Zasshi; 2004 May;95(4):675-8
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  • [Title] [Primary malignant lymphoma of the urinary bladder: a case report].
  • We report a case of primary malignant lymphoma of the urinary bladder.
  • Macrohematuria appeared, and the submucosal tumor was observed by cystoscopy, and A Transurethral bladder biopsy led to a histopathological diagnosis of non-Hodgkin's malignant lymphoma (diffuse lymphoma, large-sized cell type, B-cell type).
  • The administration of 6-course CHOP chemotherapy had an excellent effect of disappearing the tumor, bilateral hydronephrosis, and bladder-ileum fistula.
  • [MeSH-major] Lymphoma, B-Cell. Lymphoma, Large B-Cell, Diffuse. Urinary Bladder Neoplasms
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Female. Humans. Prednisone / administration & dosage. Remission Induction. Stents. Vincristine / administration & dosage

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  • (PMID = 15198002.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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21. Gono T, Shimojima Y, Hoshi K, Yamamoto K, Tokuda T, Shikama N, Matsuda M, Ikeda S: Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate. Intern Med; 2004 Feb;43(2):135-8
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  • [Title] Malignant lymphoma associated with rheumatoid arthritis, developing shortly after initiation of oral methotrexate.
  • We report a patient with rheumatoid arthritis (RA) who developed malignant lymphoma of the diffuse large B-cell type in the right submandibular region shortly after initiation of oral methotrexate (MTX).
  • Despite cessation of MTX, the lymphadenopathy did not regress, and only reached complete remission after 3 courses of CHOP therapy followed by irradiation.
  • In this patient highly active RA itself was considered to be the main cause of malignant lymphoma, and MTX might have contributed to the development by modifying the immune system.
  • When RA is highly active, MTX should be used carefully because of the possible development of malignant lymphoma as well as other serious complications.
  • [MeSH-major] Antirheumatic Agents / therapeutic use. Arthritis, Rheumatoid / complications. Arthritis, Rheumatoid / drug therapy. Lymphoma, B-Cell / etiology. Lymphoma, Large B-Cell, Diffuse / etiology. Methotrexate / therapeutic use
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Humans. Magnetic Resonance Imaging. Male. Mandibular Neoplasms / drug therapy. Mandibular Neoplasms / etiology. Middle Aged. Prednisolone / therapeutic use. Vincristine / therapeutic use

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  • (PMID = 15005257.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone; YL5FZ2Y5U1 / Methotrexate; VAP-cyclo protocol
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22. Wang FF, Su CC, Chang YH, Pan CC, Tang KT, Jap TS, Lin HD, Won JG: Primary adrenal lymphoma manifestating as adrenal incidentaloma. J Chin Med Assoc; 2003 Jan;66(1):67-71
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  • [Title] Primary adrenal lymphoma manifestating as adrenal incidentaloma.
  • Although involvement of the adrenals by malignant lymphoma is common, primary adrenal lymphoma is extremely rare.
  • Ultrasound-guided biopsy disclosed a picture of malignant lymphoma, diffuse large B cell type.
  • The patient received bilateral adrenalectomy and adjuvant chemotherapy, but succumbed 6 months later.
  • We suggest that, although rare, primary adrenal lymphoma should be considered as a possible cause of bilateral adrenal incidentalomas.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Lymphoma, Non-Hodgkin / diagnosis

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  • (PMID = 12728978.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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23. Buc D, Travade P, Kemeny JL, Bacin F: [A case of primary non-Hodgkin lymphoma of the lacrimal sac]. J Fr Ophtalmol; 2002 Nov;25(9):931-5
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  • [Title] [A case of primary non-Hodgkin lymphoma of the lacrimal sac].
  • [Transliterated title] Lymphome primitif non-hodgkinien du sac lacrymal.
  • Malignant tumors of the lacrimal sac are uncommon, and primary non-Hodgkin lymphomas are rare.
  • Pathological studies of the mass revealed diffuse malignant lymphoma with large B cells.
  • The lymphoma was classified as stage IIE using Ann Arbor staging after clinical, biological and radiological examination.
  • Six CHOP systemic chemotherapy were proposed.
  • Primary non-Hodgkin lymphoma of the lacrimal sac is extremely rare.
  • Collaboration between the ophthalmologist, anatomopathologist and oncologist allowed us to determine the type and the extension and to propose an aggressive but successful treatment in this highly malignant and very localized lymphoma.
  • [MeSH-major] Eye Neoplasms. Lymphoma, B-Cell. Nasolacrimal Duct
  • [MeSH-minor] Aged. Aged, 80 and over. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Combined Modality Therapy. Cyclophosphamide / therapeutic use. Dacryocystorhinostomy. Disease-Free Survival. Doxorubicin / therapeutic use. Female. Follow-Up Studies. Humans. Prednisone / therapeutic use. Time Factors. Tomography, X-Ray Computed. Vincristine / therapeutic use

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  • (PMID = 12515939.001).
  • [ISSN] 0181-5512
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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24. Yumura Y, Chiba K, Saito K, Hirokawa M: [Fournier's gangrene in a patient with malignant lymphoma: a case report]. Hinyokika Kiyo; 2000 Oct;46(10):735-7

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Fournier's gangrene in a patient with malignant lymphoma: a case report].
  • Pathological diagnosis was malignant lymphoma (diffuse large cell type).
  • Three weeks later, he developed reddened scrotal swelling accompanied with high fever (> 39 degrees C).
  • On admission, antibiotic chemotherapy was initiated.
  • Although his general condition was improved, scrotal necrosis had developed.
  • A computed tomography scan demonstrated thickened subcutaneous tissue over the left lumbar region.
  • Excision of necrotic tissue and sequential irrigation using povidone iodine liquid were effective.
  • The patient then underwent chemotherapy for malignant lymphoma at the internal department.
  • [MeSH-major] Fournier Gangrene / etiology. Lymphoma, Large B-Cell, Diffuse / complications
  • [MeSH-minor] Aged. Aged, 80 and over. Genital Diseases, Male / etiology. Genital Diseases, Male / surgery. Humans. Immunocompromised Host. Male. Scrotum. Treatment Outcome

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  • (PMID = 11215202.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 5
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25. Shoji T, Konno H, Tanaka T, Baba M, Kamiya K, Kaneko T, Igarashi A, Nakamura S: Pancreaticoduodenectomy for perforated gastric malignant lymphoma: report of a case. Surg Today; 2002;32(5):468-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pancreaticoduodenectomy for perforated gastric malignant lymphoma: report of a case.
  • We herein report the case of a 65-year old man with gastroduodenal malignant lymphoma (diffuse large B-cell type) accompanied with a bulbar perforation.
  • The postoperative course was uneventful and CHOP therapy (pirarubicin 30 mg/m2, cyclophosphamide 500 mg/m2, vincristine 1 mg/m2, prednisolone 30 mg/m2) was started 1 month after surgery.
  • Seven cycles of CHOP therapy markedly reduced the residual lesions including lymph nodes, and a computed tomography scan after the final chemotherapy revealed no obvious lesions.
  • [MeSH-major] Lymphoma, B-Cell / surgery. Lymphoma, Large B-Cell, Diffuse / surgery. Pancreaticoduodenectomy. Stomach Neoplasms / surgery

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  • (PMID = 12061704.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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26. Yabuki K, Tamasaki Y, Satoh K, Maekawa T, Matsumoto M: Primary gastric lymphoma with spontaneous perforation: report of a case. Surg Today; 2000;30(11):1030-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary gastric lymphoma with spontaneous perforation: report of a case.
  • Primary gastric lymphoma with spontaneous perforation is rare.
  • Emergency endoscopic examination showed a perforated gastric tumor in the lower body of the greater curvature, and a distal subtotal gastrectomy with lymph node dissection was performed.
  • Pathological examination confirmed a diagnosis of B-cell malignant lymphoma of the diffuse, medium-sized cell type.
  • According to the Ann Arbor and Naqvi classifications, the lymphoma was stage II and stage III, respectively.
  • Postoperative adjuvant chemotherapy comprising cyclophosphamide, doxorubicin, vincristine, and prednisolone (CHOP) was given.
  • [MeSH-major] Intestinal Perforation / etiology. Lymphoma, B-Cell / complications. Stomach Neoplasms / complications
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols. Chemotherapy, Adjuvant. Cyclophosphamide. Doxorubicin. Humans. Male. Middle Aged. Prednisone. Rupture, Spontaneous. Vincristine

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  • (PMID = 11110402.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
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27. Ebata K, Masaki Y, Karasawa H, Okada J, Kim CG, Tsuka M, Ogawa N, Wano Y, Hirose Y, Sugai S: [Marginal zone lymphoma associated with Sjögren's syndrome and hepatitis C virus infection]. Nihon Rinsho Meneki Gakkai Kaishi; 2001 Aug;24(4):160-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Marginal zone lymphoma associated with Sjögren's syndrome and hepatitis C virus infection].
  • Histology of the right parotid gland revealed malignant lymphoma, diffuse medium-sized B-cell type, and she was treated with local radiotherapy and chemotherapy.
  • She was rehospitalized in April 1998, because of recurrence of lymphoma in the stomach and the sigmoid colon.
  • Marginal zone B-cell lymphoma mainly consisted of centrocyte-like cells and lymphoepithelial lesions, and CD 20 and IgM-kappa were positive with immunohistochemical staining.
  • Lymphoma involved the gut and spleen.
  • We discuss the correlation of malignant lymphoma with Sjogren's syndrome and HCV infection.
  • [MeSH-major] Hepatitis C / complications. Lymphoma, B-Cell / etiology. Parotid Neoplasms / etiology. Sjogren's Syndrome / complications

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  • (PMID = 16578967.001).
  • [ISSN] 0911-4300
  • [Journal-full-title] Nihon Rinshō Men'eki Gakkai kaishi = Japanese journal of clinical immunology
  • [ISO-abbreviation] Nihon Rinsho Meneki Gakkai Kaishi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD20
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