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Items 1 to 34 of about 34
1. Vakiani E, Savage DG, Pile-Spellman E, El-Tamer M, Singh IR, Murty VS, Alobeid B, Bhagat G: T-Cell lymphoblastic lymphoma presenting as bilateral multinodular breast masses: a case report and review of the literature. Am J Hematol; 2005 Nov;80(3):216-22
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  • [Title] T-Cell lymphoblastic lymphoma presenting as bilateral multinodular breast masses: a case report and review of the literature.
  • Non-Hodgkin lymphoma of T-cell lineage involving the breast is rare.
  • We report on a 41-year-old woman with T-cell lymphoblastic lymphoma who presented with multiple bilateral breast masses.
  • The patient was treated with intensive chemotherapy and mediastinal and whole-brain irradiation.
  • [MeSH-major] Breast Neoplasms / pathology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology

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  • (PMID = 16247747.001).
  • [ISSN] 0361-8609
  • [Journal-full-title] American journal of hematology
  • [ISO-abbreviation] Am. J. Hematol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA149719
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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2. Mizunoe S, Yamasaki T, Tokimatsu I, Kushima H, Matsunaga N, Hashinaga K, Miyazaki Y, Komatsu E, Kadota J: Sarcoidosis associated with renal masses on computed tomography. Intern Med; 2006;45(5):279-82
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  • [Title] Sarcoidosis associated with renal masses on computed tomography.
  • A 50-year-old woman was admitted to our hospital after computed tomography (CT) revealed renal masses and mediastinal lymphadenopathy.
  • Abdominal CT showed multiple low attenuation tumor-like nodules in both kidneys.
  • As lymphoma was considered likely, CT-guided renal biopsy was performed; however, histological examination of the excised specimens revealed noncaseating granulomas.
  • [MeSH-minor] Female. Glucocorticoids / therapeutic use. Humans. Kidney / radionuclide imaging. Lymphatic Diseases / etiology. Lymphatic Diseases / radiography. Mediastinum / radiography. Mediastinum / radionuclide imaging. Middle Aged. Prednisolone / therapeutic use. Tomography, X-Ray Computed. Uveitis / drug therapy. Uveitis / etiology

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  • (PMID = 16595994.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Glucocorticoids; 9PHQ9Y1OLM / Prednisolone
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3. Inokuchi T, Shincho M, Moriwaki Y, Ka T, Takahashi S, Tsutsumi Z, Lin Y, Hirota S, Yamamoto T: Coexistent B-cell lymphoma and cutaneous T-cell lymphoma. Intern Med; 2006;45(9):641-7
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  • [Title] Coexistent B-cell lymphoma and cutaneous T-cell lymphoma.
  • A physical examination showed the left cervical lymph node to be palpable, which was later shown to be caused by a diffuse large B-cell lymphoma.
  • The patient was diagnosed with concurrent mycosis fungoides and a diffuse large B-cell lymphoma.
  • Three courses of chemotherapy were performed, however, the patient died of advanced disease.
  • Autopsy findings showed that the right adrenal and soft tissue masses had an identical B-cell origin.
  • [MeSH-major] Lymphoma, B-Cell. Mycosis Fungoides. Neoplasms, Multiple Primary. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Antibiotics, Antineoplastic / administration & dosage. Antineoplastic Agents, Alkylating / administration & dosage. Antineoplastic Agents, Phytogenic / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Fatal Outcome. Humans. Male. Radionuclide Imaging. Tomography, X-Ray Computed. Vincristine / administration & dosage

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  • (PMID = 16755097.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide
  • [Number-of-references] 19
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4. Franco MI, Waisberg J, Lopes LS: Multiple lymphomatous polyposis of the gastrointestinal tract. Sao Paulo Med J; 2004 May 6;122(3):131-3

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  • [Title] Multiple lymphomatous polyposis of the gastrointestinal tract.
  • CONTEXT: Gastrointestinal multiple lymphomatous polyposis is a rare type of malignant lymphoma that has aggressive biological behavior, early systemic dissemination and poor prognosis.
  • It is considered to be a manifestation of non-Hodgkin lymphoma and represents the gastrointestinal counterpart of mantle cell nodal lymphoma.
  • OBJECTIVE: A case of gastrointestinal multiple lymphomatous polyposis is presented and the anatomopathological, clinical, diagnostic and treatment aspects of this unusual neoplasia are discussed.
  • An opaque enema showed multiple polypoid lesions, especially in the cecum.
  • A rectal biopsy revealed infiltration of the mucosa and submucosa by diffuse lymphoma consisting of small cleaved cells.
  • After two cycles of chemotherapy there was a worsening of the general state, with an increase in the dimensions of the abdominal masses and sepsis, accompanied by progressive respiratory insufficiency, leading to death.
  • [MeSH-major] Gastrointestinal Neoplasms / pathology. Intestinal Polyposis / pathology. Lymphoma, Mantle-Cell / pathology

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  • (PMID = 15448813.001).
  • [ISSN] 1516-3180
  • [Journal-full-title] São Paulo medical journal = Revista paulista de medicina
  • [ISO-abbreviation] Sao Paulo Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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5. Lee CC, Chen WM, Yen CC, Wu HD, Chen TH: Malignant lymphoma in an atomic-bomb survivor. J Chin Med Assoc; 2009 Jul;72(7):388-93

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  • [Title] Malignant lymphoma in an atomic-bomb survivor.
  • Spinal malignant lymphoma among these survivors is rare in established studies from Japan or the United States.
  • Both follicular lymphoma over the right elbow region and vertebral malignant lymphoma were found when she turned 81 years old.
  • However, thoracolumbar spine magnetic resonance imaging showed multiple infiltrative soft tissue masses involving vertebral bodies at the T10-11 level.
  • Computed tomography-guided biopsy further showed lymphocyte infiltration.
  • Fortunately, the neurological deficit was improved after chemotherapy.
  • The diagnosis of malignant lymphoma in atomic bomb survivors should be more careful and aggressive, even when their bone scan results show negative findings.
  • [MeSH-major] Epidural Neoplasms / etiology. Lymphoma, Follicular / etiology. Neoplasms, Radiation-Induced / etiology. Nuclear Warfare. Survivors

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  • (PMID = 19581148.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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6. Rodriguez VR, Joshi A, Peng F, Rabah RM, Stockmann PT, Savaşan S: Positron emission tomography in subcutaneous panniculitis-like T-cell lymphoma. Pediatr Blood Cancer; 2009 Mar;52(3):406-8
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  • [Title] Positron emission tomography in subcutaneous panniculitis-like T-cell lymphoma.
  • Subcutaneous panniculitis-like T-cell lymphoma (SPTCL), an uncommon disorder, was diagnosed in a 17-year-old female when she presented with multiple hard subcutaneous masses that developed over 3 years.
  • She was treated on chemotherapy consisting of cyclophosphamide, doxorubicin, vincristine, and prednisone.
  • Pre- and post-treatment positron emission tomography study demonstrated dramatic resolution of the subcutaneous lesions indicating its usefulness in SPTCL staging and treatment response monitoring.
  • [MeSH-major] Lymphoma, T-Cell / diagnosis. Panniculitis / diagnosis
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Female. Follow-Up Studies. Humans. Positron-Emission Tomography


7. Mlika M, Chelly I, Benrhouma M, Haouet S, Horchani A, Zitouna MM, Kchir N: A Primary Testicular Diffuse Large B-cell Lymphoma Belonging to the Germinal Center B-cell-like Group. J Clin Med Res; 2010 Feb;2(1):47-9
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  • [Title] A Primary Testicular Diffuse Large B-cell Lymphoma Belonging to the Germinal Center B-cell-like Group.
  • Testicular lymphoma was first reported by Malassez and Curling in 1866.
  • Primary testicular lymphoma constitutes only 1 - 7% of all testicular neoplasms and less than 1% of all non Hodgkin lymphoma.
  • The authors report a new case of primary testicular lymphoma and highlight its diagnostic and therapeutic challenge.
  • Radiological findings consisted in multiple hypoechoic masses that corresponded in histological examination to a diffuse intratubular lymphomatous infiltration situated away from the spermatic cord, the epididymis, ductuli efferentes and rete testis.
  • The patient underwent full staging for lymphoma showing no evidence of extra-testicular involvement by lymphoma and no lymph nodes.
  • The diagnosis of stage I primary testicular large B-cell lymphoma of germinal center B-cell-like group was made.
  • The patient is now treated by chemotherapy.
  • Primary testicular lymphoma is a rare tumour whose diagnosis is based on histological findings.
  • Treatment modalities consist in surgical excision, chemotherapy and radiation therapy but the accurate procedures are not standardized.
  • KEYWORDS: Testicular lymphoma; Germinal center; B-cell.

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  • (PMID = 22457702.001).
  • [ISSN] 1918-3003
  • [Journal-full-title] Journal of clinical medicine research
  • [ISO-abbreviation] J Clin Med Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3299176
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8. Matsubara H, Watanabe K, Sakai H, Chang H, Fujino H, Higashi Y, Kobayashi M, Adachi S, Seto S, Nakahata T: Rapid improvement of paraplegia caused by epidural involvements of Burkitt's lymphoma with chemotherapy. Spine (Phila Pa 1976); 2004 Jan 1;29(1):E4-6
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  • [Title] Rapid improvement of paraplegia caused by epidural involvements of Burkitt's lymphoma with chemotherapy.
  • OBJECTIVE: The authors present a case of atypical Burkitt's lymphoma with multiple epidural involvements.
  • MATERIALS AND METHODS: Because the patient showed rapid neurologic deterioration, we started chemotherapy and high-dose steroids without laminectomy or radiotherapy immediately after a tumor biopsy from the left mandible.
  • RESULT: The combined therapies were very effective and his neurologic symptoms improved immediately.
  • The epidural involved masses disappeared in imaging studies after the first course of chemotherapy including methylprednisolone (20 mg/kg per day for 3 consecutive days and gradually tapered off over 2 weeks), vincristine (1.5 mg/m2 per day), cyclophosphamide (2 g/m2 per day for 2 days) and pirarubicin (40 mg/m2 per day).
  • After completing seven courses of chemotherapy, the patient is now fully ambulant.
  • CONCLUSION: Considering the severe late effects of laminectomy and radiotherapy, chemotherapy should be considered as a first choice of treatment for spinal cord compression caused by malignant lymphoma.
  • [MeSH-major] Burkitt Lymphoma / complications. Doxorubicin / analogs & derivatives. Epidural Neoplasms / complications. Paraplegia / drug therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child, Preschool. Cyclophosphamide / administration & dosage. Glucocorticoids / therapeutic use. Humans. Leg. Lumbar Vertebrae. Male. Methylprednisolone / therapeutic use. Pain / drug therapy. Pain / etiology. Time Factors. Treatment Outcome. Vincristine / administration & dosage

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  • (PMID = 14699290.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucocorticoids; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; D58G680W0G / pirarubicin; X4W7ZR7023 / Methylprednisolone
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9. Boni L, Benevento A, Dionigi G, Cabrini L, Dionigi R: Primary pancreatic lymphoma. Surg Endosc; 2002 Jul;16(7):1107-8
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  • [Title] Primary pancreatic lymphoma.
  • Primary pancreatic lymphoma (PPL) is a rare form of extranodal lymphoma (less than 0.5% of pancreatic tumors) originating from the pancreatic parenchyma.
  • Histopathological examination is usually mandatory to obtain a definitive diagnosis since symptoms and radiological features are quite similar to those of other pancreatic masses.
  • Percutaneous fine-needle aspiration (FNA) of the pancreas requires experienced cytopathologists as well as advanced immunohistochemical assays to obtain a final diagnosis on a small amount of tissue.
  • Abdominal computed tomography scan confirmed a diffuse enlargement of the head and body of the pancreas associated with lymphadenopathy along the lesser gastric curvature.
  • Multiple biopsies of the pancreatic head were taken and lymphadenectomy along the lesser curvature and the hepatic hilus was also performed.
  • The definitive histopathological examination of the pancreatic specimen revealed a primary low-grade non-Hodgkin B cell pancreatic lymphoma.
  • The postoperative course was unremarkable; the patient underwent systemic chemotherapy regime for low-grade B cell Hodgkin lymphoma and he was symptom free at 9-month follow-up.
  • [MeSH-major] Lymphoma, B-Cell / surgery. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Diabetes Mellitus, Type 1 / surgery. Diagnostic Techniques, Surgical. Humans. Laparoscopy / methods. Lymph Node Excision / methods. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 11984658.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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10. Agarwala B, Rubin CM: Intracardiac lymphoma in a child: successful treatment with chemotherapy alone. Pediatr Cardiol; 2000 Jul-Aug;21(4):401-2
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  • [Title] Intracardiac lymphoma in a child: successful treatment with chemotherapy alone.
  • A 5-year-old female child with history of non-Hodgkin's lymphoma presented with cough and palpitation.
  • Transthoracic echocardiogram revealed multiple large tumor masses within the right and the left atrium.
  • The tumor resolved completely with chemotherapy without any surgical intervention.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Heart Neoplasms / drug therapy. Lymphoma, B-Cell / drug therapy

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  • (PMID = 10865026.001).
  • [ISSN] 0172-0643
  • [Journal-full-title] Pediatric cardiology
  • [ISO-abbreviation] Pediatr Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; E7WED276I5 / 6-Mercaptopurine
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11. Seker M, Ozdemir B, Bilici A, Ustaalioğlu BB, Sonmez B, Yilmaz BE, Kurnaz E, Gumus M, Yaylaci M: Bilateral conjunctival MALT lymphoma mimicking chronic conjunctivitis. Onkologie; 2010;33(6):317-20
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  • [Title] Bilateral conjunctival MALT lymphoma mimicking chronic conjunctivitis.
  • CASE REPORT: A 60-year-old man was referred to our clinic with bilateral conjunctival masses in May 2005.
  • Although a partial response was achieved, 2 months after the treatment, the patient's complaints returned.
  • He presented with bilateral conjunctival masses resembling conjunctival lymphoma, and a bilateral diagnostic biopsy was performed.
  • Histopathological evaluation of the biopsy specimens revealed mucosa-associated lymphoid tissue (MALT) lymphoma.
  • The patient received CVP chemotherapy (cyclophosphamide, vincristine, prednisolone).
  • After 6 courses of chemotherapy, he achieved partial remission in both eyes.
  • [MeSH-major] Conjunctival Neoplasms / diagnosis. Conjunctivitis, Inclusion / diagnosis. Lymphoma, B-Cell, Marginal Zone / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Chronic Disease. Conjunctiva / pathology. Cyclophosphamide / administration & dosage. Diagnosis, Differential. Follow-Up Studies. Humans. Male. Middle Aged. Prednisone / administration & dosage. Remission Induction. Vincristine / administration & dosage

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  • (PMID = 20523096.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; COP protocol 2
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12. Meshref M, Sassolas F, Schell M, Chalabreysse L, Chassagne C, Mialou V, Marec Bérard P, Di Filippo S, Bergeron C: Primary cardiac Burkitt lymphoma in a child. Pediatr Blood Cancer; 2004 Apr;42(4):380-3
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  • [Title] Primary cardiac Burkitt lymphoma in a child.
  • Primary cardiac lymphoma (PCL) is a rare and usually fatal malignancy, seldom reported in children.
  • This report describes the case of a 10-year-old boy who presented with multiple intracardiac masses which, when biopsied, proved to be small non-cleaved cell (Burkitt's) lymphoma.
  • The first two cycles of chemotherapy according to the LMB 96 protocol were given under close cardiological supervision, with good response.
  • The treatment was then continued with full-dose chemotherapy, without any cardiological complication.
  • The patient who was treated by chemotherapy alone remains in complete remission 36 months after the end of treatment and can presently be considered as cured, without late cardiac effect.
  • [MeSH-major] Burkitt Lymphoma / drug therapy. Heart Neoplasms / drug therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Child. Disease-Free Survival. Echocardiography. Humans. Male. Remission Induction / methods

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  • [Copyright] Copyright 2004 Wiley-Liss, Inc.
  • (PMID = 14966837.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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13. Noronha V, Shafi NQ, Obando JA, Kummar S: Primary non-Hodgkin's lymphoma of the liver. Crit Rev Oncol Hematol; 2005 Mar;53(3):199-207
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  • [Title] Primary non-Hodgkin's lymphoma of the liver.
  • We review the literature on primary hepatic lymphoma (PHL).
  • PHL is a rare malignancy, and constitutes about 0.016% of all cases of non-Hodgkin's lymphoma.
  • Imaging studies reveal solitary, or less often, multiple masses in the liver.
  • The predominant histology is B-cell lymphoma, most commonly diffuse large cell type.
  • Most patients are treated with chemotherapy, with some physicians employing a multimodality approach incorporating surgery and radiotherapy with chemotherapy.
  • The prognosis is variable, with good response to early aggressive combination chemotherapy.
  • [MeSH-major] Liver Neoplasms / pathology. Lymphoma, Non-Hodgkin / pathology
  • [MeSH-minor] B-Lymphocytes / pathology. Combined Modality Therapy. Humans. Prognosis

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  • (PMID = 15718146.001).
  • [ISSN] 1040-8428
  • [Journal-full-title] Critical reviews in oncology/hematology
  • [ISO-abbreviation] Crit. Rev. Oncol. Hematol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 52
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14. Riad R, Omar W, Sidhom I, Zamzam M, Zaky I, Hafez M, Abdel-Dayem HM: False-positive F-18 FDG uptake in PET/CT studies in pediatric patients with abdominal Burkitt's lymphoma. Nucl Med Commun; 2010 Mar;31(3):232-8
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  • [Title] False-positive F-18 FDG uptake in PET/CT studies in pediatric patients with abdominal Burkitt's lymphoma.
  • INTRODUCTION: In pediatric patients with abdominal Burkitt's lymphoma, the involvement of the gastrointestinal tract and abdominal lymph nodes are the main presenting feature of the disease.
  • Chemotherapy is the main treatment modality and could be preceded by surgical excision of the abdominal masses.
  • To achieve cure or long-term disease-free survival a balance has to be struck between aggressive chemotherapy and the probability of tumor necrosis secondary to treatment complicated by acute infections, perforation or intestinal bleeding.
  • F-18 fluorodeoxyglucose-positron emission tomography/computed tomography (F-18 FDG-PET/CT) has been recommended over conventional imaging modalities for the follow-up of these patients and for monitoring treatment response.
  • This is especially important as post-therapy complications might present with nonspecific and nonurgent symptoms.
  • At the same time initiating a second course of salvage chemotherapy is risky.
  • AIM OF STUDY: Retrospectively reviewed F-18 FDG-PET/CT studies for 28 pediatric patients with abdominal Burkitt's lymphoma and diffuse large B-cell lymphoma after their treatment with chemotherapy or surgery.
  • One patient had multiple recurrent lesions in the abdomen after the initial surgical excision and before starting chemotherapy.
  • CONCLUSION: This study confirms the high incidence of tumor necrosis and inflammation after chemotherapy for the abdominal Burkitt's lymphoma and consequently, the incidence of true-positive F-18 FDG studies is low.
  • [MeSH-major] Burkitt Lymphoma / radionuclide imaging. Fluorodeoxyglucose F18 / pharmacology. Positron-Emission Tomography / methods. Radiopharmaceuticals / pharmacology. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Child. Child, Preschool. False Positive Reactions. Female. Humans. Lymphoma, Non-Hodgkin / radionuclide imaging. Male. Necrosis. Reproducibility of Results. Retrospective Studies

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  • (PMID = 20032800.001).
  • [ISSN] 1473-5628
  • [Journal-full-title] Nuclear medicine communications
  • [ISO-abbreviation] Nucl Med Commun
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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15. Fadiora SO, Mabayoje VO, Aderoumu AO, Adeoti ML, Olatoke SA, Oguntola AS: Generalised Burkitt's lymphoma involving both breasts--a case report. West Afr J Med; 2005 Jul-Sep;24(3):280-2
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  • [Title] Generalised Burkitt's lymphoma involving both breasts--a case report.
  • BACKGROUND: Burkitt's lymphoma is a disease of children age ranging 8-10 years.
  • Lymphoma involving the breast is an unusual clinical entity, which is rarely distinguished preoperatively from other more common forms of breast cancer.
  • The Management differs from the more typical adenocarcinoma of the breast in that the emphasis is on systemic therapy.
  • CASE: We report a 27-year-old pregnant Nigerian civil servant at 28 weeks gestation, who presented with multiple organ swellings including both breasts.
  • She was diagnosed histologically as primary breast Burkitt's lymphoma.
  • She was treated with systemic chemotherapy after spontaneous abortion.
  • CONCLUSION: Compared with breast carcinoma, primary breast lymphoma is a rare disease but should be considered in the differential diagnosis of breast masses.
  • [MeSH-major] Breast Neoplasms / pathology. Burkitt Lymphoma / pathology. Pregnancy Complications, Neoplastic / pathology

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  • (PMID = 16276714.001).
  • [ISSN] 0189-160X
  • [Journal-full-title] West African journal of medicine
  • [ISO-abbreviation] West Afr J Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nigeria
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16. Stancu M, Jones D, Vega F, Medeiros LJ: Peripheral T-cell lymphoma arising in the liver. Am J Clin Pathol; 2002 Oct;118(4):574-81
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  • [Title] Peripheral T-cell lymphoma arising in the liver.
  • We report 3 cases of primary hepatic peripheral T-cell lymphoma (PTCL).
  • Imaging studies demonstrated marked hepatomegaly without focal lesions in 1 patient and multiple discrete tumor masses in 2 patients.
  • One patient died of disease shortly after diagnosis, and 2 patients treated with multiagent chemotherapy are in clinical remission with 12 and 84 months of clinicalfollow-up, respectively.
  • These neoplasms respond to chemotherapy, suggesting that this disease is curable if diagnosed at an early stage.
  • [MeSH-major] Liver Neoplasms / pathology. Lymphoma, T-Cell, Peripheral / pathology

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  • (PMID = 12375645.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Receptors, Antigen, T-Cell, gamma-delta
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17. Stefan DC, Van Toorn R, Andronikou S: Spinal compression due to Burkitt lymphoma in a newly diagnosed HIV-infected child. J Pediatr Hematol Oncol; 2009 Apr;31(4):252-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal compression due to Burkitt lymphoma in a newly diagnosed HIV-infected child.
  • We describe a newly diagnosed HIV-infected child, without prior history of AIDS-defining disease, who presented with Burkitt lymphoma-related cauda equina syndrome that rapidly progressed to a flaccid paraplegia.
  • Diagnosis was confirmed on biopsy and magnetic resonance imaging of the spine showed multiple epidural masses with involvement of several vertebral bodies, cord edema and compression of the cord and cauda equina.
  • Chemotherapy (LMB 89 modified protocol) was initiated immediately after histopathologic confirmation, together with highly active antiretroviral therapy.
  • A follow-up magnetic resonance imaging 6 weeks later showed segmental cord atrophy at the site of previous edema despite complete resolution of all the epidural masses.
  • The patient is the first reported case of Burkitt lymphoma-related spinal cord compression as an initial AIDS-defining illness, in a 10-year-old child.
  • The outcome of the case highlights the importance of early diagnosis and prompt treatment of this aggressive tumor to avoid permanent neurologic deficits.
  • [MeSH-major] Burkitt Lymphoma / complications. HIV Infections / complications. Polyradiculopathy / etiology. Spinal Cord Compression / etiology. Spinal Cord Neoplasms / complications

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  • (PMID = 19346875.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Hon C, Chan RT, Ma ES, Shek TW, Yau K, Au WY: Lymphomatous proptosis as a novel feature of mantle cell lymphoma. Leuk Lymphoma; 2006 Jan;47(1):71-5
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  • [Title] Lymphomatous proptosis as a novel feature of mantle cell lymphoma.
  • We describe eight cases of acute proptosis due to mantle cell lymphoma (MCL), among 26 consecutive MCL cases.
  • The median time of onset was 29 months (range 0-102) from diagnosis.
  • Two cases presented initially with orbital masses while five as sudden disease progression after multiple courses of chemotherapy.
  • In each case, there was dramatic loss of vision and severe proptosis, which uniformly responded to radiotherapy and/or further chemotherapy.
  • [MeSH-major] Exophthalmos / etiology. Lymphoma, Mantle-Cell / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Combined Modality Therapy. Disease Progression. Fatal Outcome. Female. Humans. Male. Middle Aged. Orbital Neoplasms / diagnosis. Orbital Neoplasms / therapy. Recurrence. Survival Rate. Treatment Outcome

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  • (PMID = 16321830.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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19. Chaiwun B, Sukhamwang N, Ya-In C, Shuangshoti S: Bilateral low-grade B-cell lymphoma of the breast: a case report with cytological, histological and immunohistochemical studies. J Med Assoc Thai; 2009 Jun;92(6):865-7
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  • [Title] Bilateral low-grade B-cell lymphoma of the breast: a case report with cytological, histological and immunohistochemical studies.
  • A 45-year-old woman presented with bilateral palpable breast masses, which were clinically suspicious of either mammary carcinomas or phyllodes tumors.
  • Fine needle aspiration (FNA) study suggested low-grade lymphoma.
  • Histological and immunohistochemical studies of an incisional biopsy specimen of the left breast lesion confirmed the diagnosis of low-grade B-cell lymphoma.
  • Computerized tomographic scans of chest and abdomen revealed multiple lymphadenopathy in the mediastinum and intra-abdomen.
  • After receiving chemotherapy, marked reduction in size of both breast masses and the internal lymph nodes was observed.
  • FNA is an inexpensive diagnostic tool for breast lumps that can reliably distinguish carcinoma, sarcoma and lymphoma.
  • Although it is often difficult for the cytological study to differentiate low-grade lymphoma from reactive lymphoid proliferation, FNA results in combination with clinical and radiological studies (triple testing) generally provide guidance for appropriate investigations, and helps avoiding unnecessary major operation.
  • [MeSH-major] Breast / cytology. Immunohistochemistry. Lymphoma, B-Cell / pathology. Lymphoma, Non-Hodgkin / pathology
  • [MeSH-minor] Antineoplastic Agents, Alkylating / therapeutic use. Antineoplastic Agents, Phytogenic / therapeutic use. Biopsy, Fine-Needle. Cyclophosphamide / therapeutic use. Female. Glucocorticoids / therapeutic use. Humans. Lymphatic Diseases. Middle Aged. Prednisolone / therapeutic use. Vincristine / therapeutic use

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  • (PMID = 19530595.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Antineoplastic Agents, Phytogenic; 0 / Glucocorticoids; 5J49Q6B70F / Vincristine; 8N3DW7272P / Cyclophosphamide; 9PHQ9Y1OLM / Prednisolone
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20. Cornfield DB, Papiez JS, Lynch JT, Rimsza LM: Natural killer-like T-cell lymphoma of the parotid in a patient infected with human immunodeficiency virus. Arch Pathol Lab Med; 2002 Jun;126(6):738-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Natural killer-like T-cell lymphoma of the parotid in a patient infected with human immunodeficiency virus.
  • A 42-year-old man with acquired immunodeficiency syndrome developed a mass of the right parotid gland and multiple hepatic masses.
  • Hematoxylin-eosin-stained sections of the parotid lesion showed a diffuse infiltrate of large mononuclear cells with vesicular nuclei and prominent nucleoli, consistent with a non-Hodgkin lymphoma.
  • To our knowledge, this is the first reported case of T-cell lymphoma of the parotid in a patient infected with human immunodeficiency virus.
  • After 2 separate chemotherapy regimens, the patient achieved clinical remission for 1(1/2) years; he then developed progressive pulmonary lesions and died.
  • [MeSH-major] HIV / isolation & purification. Killer Cells, Natural / pathology. Lymphoma, AIDS-Related / pathology. Lymphoma, T-Cell / pathology. Parotid Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD / analysis. Antigens, CD45 / analysis. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biomarkers, Tumor / analysis. Cyclophosphamide / administration & dosage. DNA, Neoplasm / analysis. Doxorubicin / administration & dosage. Fatal Outcome. Flow Cytometry. Gene Rearrangement, gamma-Chain T-Cell Antigen Receptor / genetics. Herpesvirus 4, Human / isolation & purification. Herpesvirus 4, Human / physiology. Humans. Male. Polymerase Chain Reaction. Prednisone / administration & dosage. RNA, Viral / analysis. Vincristine / administration & dosage

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  • (PMID = 12033970.001).
  • [ISSN] 0003-9985
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / RNA, Viral; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; EC 3.1.3.48 / Antigens, CD45; VB0R961HZT / Prednisone; CHOP protocol
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21. Shimamoto T, Hayashi S, Ando K, Yguchi M, Miyazawa K, Kimura Y, Mukai K, Serizawa H, Ohyashiki K: Anaplastic large-cell lymphoma which showed severe inflammatory status and myelodysplasia with increased VEGF and IL-6 serum levels after long-term immunosuppressive therapy. Am J Hematol; 2001 Jan;66(1):49-52
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  • [Title] Anaplastic large-cell lymphoma which showed severe inflammatory status and myelodysplasia with increased VEGF and IL-6 serum levels after long-term immunosuppressive therapy.
  • We report a patient with anaplastic large-cell lymphoma (ALCL) who has been given immunosuppressive therapy for Evans syndrome for 10 years.
  • He was admitted with spike fever, intra-abdominal lymphadenopathy, and multiple liver masses.
  • Examination of biopsy specimens obtained by para-aortic lymph nodes and liver masses resulted in a diagnosis of ALCL.
  • He was treated with combination chemotherapy (ABVD regimen), achieving complete remission.
  • Myelodysplasia and serum IL-6 and VEGF also normalized after treatment.
  • We assumed that ALCL resulted from long-term immunosuppressive therapy and that the up-regulation of IL-6 and VEGF played a role in pathogenesis of this type of lymphoma.
  • [MeSH-major] Autoimmune Diseases / drug therapy. Cyclosporine / adverse effects. Endothelial Growth Factors / blood. Immunosuppressive Agents / adverse effects. Interleukin-6 / blood. Lymphokines / blood. Lymphoma, Large B-Cell, Diffuse / drug therapy. Myelodysplastic Syndromes / etiology. Pancytopenia / drug therapy. Prednisolone / adverse effects
  • [MeSH-minor] Abdominal Pain / etiology. Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / administration & dosage. Bone Marrow / pathology. CD4-CD8 Ratio. Cell Lineage. Combined Modality Therapy. DNA, Neoplasm / analysis. DNA, Viral / analysis. Dacarbazine / administration & dosage. Doxorubicin / administration & dosage. Fever / etiology. Fibroblast Growth Factor 2 / blood. Gene Rearrangement, B-Lymphocyte. Humans. Immunocompromised Host. Inflammation. Lymph Nodes / pathology. Male. Middle Aged. Remission Induction. Splenectomy. Syndrome. Vascular Endothelial Growth Factor A. Vascular Endothelial Growth Factors. Vinblastine / administration & dosage

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  • (PMID = 11426493.001).
  • [ISSN] 0361-8609
  • [Journal-full-title] American journal of hematology
  • [ISO-abbreviation] Am. J. Hematol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / DNA, Viral; 0 / Endothelial Growth Factors; 0 / Immunosuppressive Agents; 0 / Interleukin-6; 0 / Lymphokines; 0 / Vascular Endothelial Growth Factor A; 0 / Vascular Endothelial Growth Factors; 103107-01-3 / Fibroblast Growth Factor 2; 11056-06-7 / Bleomycin; 5V9KLZ54CY / Vinblastine; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; 83HN0GTJ6D / Cyclosporine; 9PHQ9Y1OLM / Prednisolone; ABVD protocol
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22. Ariad S, Benharroch D, Lupu L, Davidovici B, Dupin N, Boshoff C: Early peripheral lymph node involvement of human herpesvirus 8-associated, body cavity-based lymphoma in a human immunodeficiency virus-negative patient. Arch Pathol Lab Med; 2000 May;124(5):753-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Early peripheral lymph node involvement of human herpesvirus 8-associated, body cavity-based lymphoma in a human immunodeficiency virus-negative patient.
  • Human herpesvirus 8 is also found in an unusual clinicopathologic form of body cavity-based B-cell lymphoma, which has been named primary effusion lymphoma (PEL) and occurs primarily in HIV-positive patients.
  • PEL is characterized by the formation of lymphomatous effusions, without obvious lymphadenopathy, tumor masses, or bone marrow involvement.
  • We describe a case of an HHV-8-associated lymphoma, with ascites, pleural effusion, and axillary lymphadenopathy in an HIV-negative patient.
  • The patient was a 68-year-old Jewish man of North African extraction, with a previous history of coronary bypass surgery and multiple blood transfusions.
  • The pleural fluid contained large atypical lymphoid cells and was suggestive of lymphoma but could not provide a conclusive diagnosis of PEL.
  • The patient did not respond to combination chemotherapy with cyclophosphamide, doxorubicin, vincristine sulfate, and prednisone and progressively developed, massive intra-abdominal solid tumor formation.
  • [MeSH-major] HIV Seronegativity. Herpesvirus 8, Human / isolation & purification. Lymph Nodes / pathology. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / virology
  • [MeSH-minor] Aged. Antigens, CD30 / analysis. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Axilla. Biopsy. Fatal Outcome. Humans. Male. Mucin-1 / analysis. Pleural Effusion, Malignant / etiology. Pleural Effusion, Malignant / radiography. Polymerase Chain Reaction

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  • (PMID = 10782162.001).
  • [ISSN] 0003-9985
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / Mucin-1
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23. Pinho-Apezzato ML, Tannuri U, Tannuri AC, Mello ES, Lima F, Gibelli NE, Santos MM, Ayoub AA, Maksoud-Filho JG, Velhote MC, Silva MM, Andrade WC, Miyatani HT: Multiple clinical presentations of lymphoproliferative disorders in pediatric liver transplant recipients: a single-center experience. Transplant Proc; 2010 Jun;42(5):1763-8
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  • [Title] Multiple clinical presentations of lymphoproliferative disorders in pediatric liver transplant recipients: a single-center experience.
  • The age at diagnosis ranged from 12 to 258 months (median, 47), and the time from transplantation ranged from 1 to 84 months (median, 13).
  • The clinical signs at presentation were anemia (92.3%), diarrhea and vomiting (69.2%), recurrent upper airway infections (38.4%), Waldeyer ring lymphoid tissue hypertrophy (23.0%), abdominal mass lesions (30.7%), massive cervical and mediastinal adenopathy (15.3%), or gastrointestinal and respiratory symptoms (30.7%).
  • One child developed fulminant hepatic allograft failure secondary to graft involvement by PTLD.
  • Polymorphic PTLD was diagnosed in 6 patients; 7 had the diagnosis of lymphoma.
  • Treatment consisted of stopping immunosuppression as well as starting intravenous gancyclovir and anti-CD20 monoclonal antibody therapy.
  • The other symptoms that may be linked to the diagnosis of PTLD are pancytopenia, tonsil and adenoid hypertrophy, cervical or mediastinal lymph node enlargement, as well as abdominal masses.
  • Despite numerous advances, the optimal treatment approach for PTLD is not completely known and the mortality rate is still high.
  • [MeSH-minor] Biliary Atresia / surgery. Child. Child, Preschool. Colonic Neoplasms / pathology. Cyclosporine / therapeutic use. Drug Therapy, Combination. Epstein-Barr Virus Infections / epidemiology. Female. Herpesvirus 4, Human / isolation & purification. Humans. Immunosuppressive Agents / therapeutic use. Infant. Lymph Nodes / pathology. Lymphoma, B-Cell / pathology. Male. Prednisone / therapeutic use. Retrospective Studies. Survivors. Tacrolimus / therapeutic use

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  • (PMID = 20620519.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; 83HN0GTJ6D / Cyclosporine; VB0R961HZT / Prednisone; WM0HAQ4WNM / Tacrolimus
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24. Chandra P, Wen YH, Tuli S, Raphael BG, Amorosi EL, Medeiros LJ, Ibrahim S: Postchemotherapy histiocyte-rich pseudotumor involving the spleen. Am J Clin Pathol; 2009 Sep;132(3):342-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Each patient had a history of diffuse large B-cell lymphoma, treated with multiagent chemotherapy.
  • Computed tomography scans performed on both patients showed splenic masses.
  • A positron emission tomography scan performed on 1 patient showed increased metabolic activity.
  • The preoperative diagnosis in both patients was recurrent lymphoma, prompting splenectomy.
  • The splenectomy specimens showed multiple, tan-white, firm nodules, up to 3.5 cm in diameter, that were histologically composed of central necrotic B cells (CD20+/CD3-), consistent with necrotic lymphoma, surrounded by numerous lipid-laden (xanthomatous) histiocytes.
  • Clinical staging studies at the time of splenectomy showed no other sites of disease.
  • We conclude that these histologic and immunophenotypic findings represent chemotherapy-induced tumor necrosis with a florid histiocytic reaction mimicking residual viable lymphoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Histiocytosis / etiology. Histiocytosis / pathology. Lymphoma, Large B-Cell, Diffuse / drug therapy. Spleen / drug effects

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  • (PMID = 19687310.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Loggins JP, Urquhart A: Preoperative distinction of parotid lymphomas. J Am Coll Surg; 2004 Jul;199(1):58-61
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  • BACKGROUND: Surgical parotidectomies place parotid lymphoma patients at increased risk of morbidity because of the diffuse infiltrative nature of the disease.
  • These tumors usually respond to radiotherapy or chemotherapy, but are difficult to distinguish from other benign parotid gland tumors preoperatively.
  • The lymphoma cases included four patients with a history of autoimmune disease, and four with a previous diagnosis of lymphoma.
  • Palpable painless masses were present in all cases (14 right, 7 left, 1 bilateral).
  • Two patients had multiple palpable parotid nodules and five had palpable cervical adenopathy.
  • Of 17 patients receiving preoperative CT scans, 4 more patients were revealed to have bilateral disease, 7 more patients had cervical adenopathy, and 5 more patients had multiple parotid nodules.
  • Preoperative fine needle aspiration biopsy was performed in 10 of the 22 lymphomas, revealing 3 reactive nodes, 3 suspicious for lymphoma and 3 nondiagnostic.
  • CONCLUSIONS: Although parotid lymphomas are uncommon, a history of autoimmune disease or previous lymphoma; clinical or radiologic evidence of bilateral, multiple, or poorly circumscribed parotid lesions; and cervical lymphadenopathy should suggest this diagnosis.
  • This may alter the proposed surgery and decrease the potential morbidity associated with superficial parotidectomy in cases of parotid lymphoma.
  • [MeSH-major] Lymphoma / diagnosis. Parotid Gland / radiography. Parotid Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Preoperative Care. Retrospective Studies. Surgical Procedures, Operative / methods. Tomography, X-Ray Computed

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  • (PMID = 15217631.001).
  • [ISSN] 1072-7515
  • [Journal-full-title] Journal of the American College of Surgeons
  • [ISO-abbreviation] J. Am. Coll. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Wong MT, Eu KW: Primary colorectal lymphomas. Colorectal Dis; 2006 Sep;8(7):586-91
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  • Patients often present delayed with nonspecific symptoms and consequently have advanced disease at the time of diagnosis.
  • Treatment often involves a multimodality approach, combining surgery and chemotherapy, with the use of radiotherapy in selected cases.
  • PATIENTS AND METHODS: We reviewed all cases of primary colorectal lymphoma seen at our institution from 1989 to 1999.
  • Patients were included based on standard diagnostic criteria for primary intestinal lymphoma established by Dawson in 1961.
  • The following clinical information was obtained: age, sex, presentation, site of tumour, operation performed, histology, length of stay, intraoperative complications, adjuvant therapy and duration of follow-up.
  • The type of lymphoma was classified according to the WHO classification system.
  • For staging, a modification of the Ann Arbor system for gastrointestinal lymphoma, proposed by Musshoff, was used.
  • The lesions manifested in a variety of ways, ranging from solitary fungating masses to multiple colonic polyps.
  • Eleven patients (78.6%) received postoperative chemotherapy, with a regimen that included cyclophosphamide, vincristine, doxorubicin and prednisone.
  • CONCLUSION: Primary colorectal lymphoma is a rare condition.
  • Therapy usually involves resection of the affected colon and regional lymphovascular structures, followed by adjuvant chemotherapy, with a reported 5-year survival of 27-55%.
  • [MeSH-major] Colorectal Neoplasms. Lymphoma

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  • (PMID = 16919111.001).
  • [ISSN] 1462-8910
  • [Journal-full-title] Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
  • [ISO-abbreviation] Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 29
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27. Nohgawa M, Moriguchi T, Tsudo M: [Intravascular lymphomatosis diagnosed by bone marrow biopsy]. Rinsho Ketsueki; 2000 Jul;41(7):607-11
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  • After admission, respiratory failure due to multiple pulmonary embolisms progressed, and continuous infusion of heparin had no apparent effect.
  • Bone marrow vessels filled with lymphoma cells were observed in a biopsy specimen, thus establishing a diagnosis of IVL.
  • Chemotherapy with the CHOP regimen was immediately instituted.
  • After eight courses of CHOP, low-dose etoposide therapy was administered, and no symptoms of relapse were noticed.
  • The diagnosis of IVL is difficult because it does not form masses of tumor cells.
  • [MeSH-major] Bone Marrow / pathology. Lymphoma / pathology. Vascular Neoplasms / pathology

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  • (PMID = 11020986.001).
  • [ISSN] 0485-1439
  • [Journal-full-title] [Rinshō ketsueki] The Japanese journal of clinical hematology
  • [ISO-abbreviation] Rinsho Ketsueki
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] JAPAN
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28. Ormerod C, Sarkar S, Woodcock B, White D, Lal S: Gastric ulcers and swollen kidneys: a rare diagnosis complicating Crohn's disease. BMJ Case Rep; 2010;2010
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  • Gastroscopy revealed multiple gastric ulcers.
  • A repeat CT scan showed bilateral renal masses and a renal biopsy was arranged.
  • Gastric and renal biopsies were consistent with B cell lymphoma.
  • Chemotherapy was started and resulted in improvement in CT scan findings as well as ulcer healing.
  • [MeSH-major] Crohn Disease / diagnosis. Kidney Diseases / pathology. Liver Abscess / radiography. Lymphoma, B-Cell / diagnosis. Stomach Ulcer / diagnosis
  • [MeSH-minor] Abdominal Pain / diagnosis. Abdominal Pain / etiology. Anti-Bacterial Agents / therapeutic use. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Azathioprine / therapeutic use. Biopsy, Needle. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Immunohistochemistry. Middle Aged. Recurrence. Tomography, X-Ray Computed / methods

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  • [Cites] Gut. 2005 Aug;54(8):1121-5 [16009685.001]
  • [Cites] J Clin Oncol. 2005 Aug 1;23(22):5027-33 [15955905.001]
  • [Cites] Inflamm Bowel Dis. 2007 Oct;13(10):1299-307 [17600819.001]
  • [Cites] Gut. 2008 Dec;57(12):1639-41 [18667489.001]
  • [Cites] Lancet. 2009 Nov 7;374(9701):1617-25 [19837455.001]
  • (PMID = 22778189.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; MRK240IY2L / Azathioprine
  • [Other-IDs] NLM/ PMC3029454
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29. Vincenzi B, Finolezzi E, Fossati C, Verzì A, Santini D, Tonini G, Arullani A, Avvisati G: Unusual presentation of Hodgkin's disease mimicking inflammatory bowel disease. Leuk Lymphoma; 2001 Jul;42(3):521-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • He was treated in the past with adequate medical therapy with considerable improvement of the symptoms.
  • However, after the resolution of the last episode of abdominal pain and diarrhoea, because of multiple protruding masses and sub-stenotic regions found during a colonoscopy, the patient underwent a right enlarged hemicolectomy with jejunal resection.
  • During the surgical procedure 16 enlarged lymphnodes were removed.
  • None of the removed lymphnodes showed the presence of tumor cells, and in addition the systemic staging procedure was negative.
  • This is a rare case of primary extranodal HD localized to the colon, in a patient with a long standing history of IBD, who showed an optimal response to chemotherapy.

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  • (PMID = 11699419.001).
  • [ISSN] 1042-8194
  • [Journal-full-title] Leukemia & lymphoma
  • [ISO-abbreviation] Leuk. Lymphoma
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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30. Nishida H, Kinoshita T, Yashiro N, Ikeda Y, O'Uchi T: MR findings of granulocytic sarcoma of the breasts. Br J Radiol; 2006 Sep;79(945):e112-5
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  • The T2 weighted coronal images on MR showed both multiple ill-defined heterogeneous hyperintense masses relative to breast parenchyma; these masses were seen also with a visual washout enhancement.
  • After chemotherapy and radiotherapy, both breast masses disappeared on MR images.
  • Although the MR findings of granulocytic sarcoma were indistinguishable from those of multicentric carcinoma and malignant lymphoma, the MR images were useful for evaluating and monitoring responses to the treatments, as well as for detecting non-palpable relapsed tumours.

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  • (PMID = 16940364.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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31. Sevmis S, Pehlivan S, Shabazov R, Karakayali H, Ozcay F, Haberal M: Posttransplant lymphoproliferative disease in pediatric liver transplant recipients. Transplant Proc; 2009 Sep;41(7):2881-3
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  • Five children (4.6%), including three girls and two boys of overall mean age, 3.9 year, developed posttransplant lymphoproliferative diseases.
  • Imaging modalities identified generalized lymphadenopathy in one, multiple liver masses in one, a large portal mass in one, multiple stomach ulcers in one, and a large mediastinal mass in one recipient.
  • Four recipients were treated with chemotherapy; the remaining recipient was treated with anti-CD20 monoclonal antibodies.
  • The one recipient who had a large mediastinal mass died at 2 months after receiving the diagnosis of chemotherapy-related sepsis; the remaining four children are alive at 9, 11, 18, and 34 months after treatment.
  • [MeSH-major] Liver Transplantation / adverse effects. Lymphoma, B-Cell / epidemiology. Lymphoproliferative Disorders / epidemiology
  • [MeSH-minor] Adolescent. Adult. Child. Female. Follow-Up Studies. Humans. Liver Neoplasms / epidemiology. Liver Neoplasms / radiography. Male. Postoperative Complications / epidemiology. Survival Rate. Survivors. Time Factors. Young Adult

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  • (PMID = 19765463.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Sanson E, Gassler N, Trautwein C, Wasmuth HE: Cavitating mesenteric lymph node syndrome: a rare complication of refractory celiac disease. Z Gastroenterol; 2010 Sep;48(9):1133-7
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  • Refractory celiac disease (RCD), defined as persisting villous atrophy with crypt hyperplasia despite strict gluten-free diet, is a rare form of celiac disease with poor prognosis due to a higher rate of severe complications such as life-threatening malnutrition or the development of intestinal T-cell lymphoma.
  • During further diagnostic work-up multiple intraabdominal cystic structures were detected by a computed tomography scan and magnetic resonance imaging.
  • A laparotomy was performed to exclude T-cell lymphoma.
  • Histology of the intraabdominal cysts revealed the diagnosis of cavitating mesenteric lymph node syndrome as the underlying cause of the masses.
  • Steroid therapy was initiated which led to complete regression of diarrhoea but did not induce a diminution of mesenteric lymph nodes.
  • Three years after the diagnosis of CMLNS, the patient presented with an acute abdomen due to a small bowel perforation caused by an enteropathy associated T-cell lymphoma.
  • We discuss the differential diagnoses of intraabdominal masses in celiac disease and review the current literature on CMLNS.
  • [MeSH-minor] Chronic Disease. Humans. Male. Middle Aged. Rare Diseases / diagnosis. Rare Diseases / drug therapy. Rare Diseases / etiology. Steroids / therapeutic use. Treatment Failure

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 20839163.001).
  • [ISSN] 1439-7803
  • [Journal-full-title] Zeitschrift für Gastroenterologie
  • [ISO-abbreviation] Z Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Steroids
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33. Akçay MN: Metastatic disease in the breast. Breast; 2002 Dec;11(6):526-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Of solid tumors at other sites, the most common cancers to metastasize to the breast are, in declining order of frequency, malignant melanoma, lymphoma, lung cancer, ovarian carcinoma, soft tissue sarcoma, and gastrointestinal and genitourinary tumors.
  • Lesions that metastasize to the breast may produce changes that look similar to those of primary breast cancer on mammography, but they are more likely to be multiple, are frequently bilateral, and form a nidus of tumor cells that are usually round with fairly well-defined margins.
  • Diagnosis is generally achieved by means of fine-needle aspiration cytology or open biopsy of the breast masses.
  • In recent reports, particular importance has been attached to the performance of fine-needle aspiration cytology diagnosis, to differentiate a metastasis from a second primary tumor, thus making it possible to avoid unnecessary mastectomy and ensure that appropriate chemotherapy and radiotherapy are implemented.

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  • (PMID = 14965721.001).
  • [ISSN] 0960-9776
  • [Journal-full-title] Breast (Edinburgh, Scotland)
  • [ISO-abbreviation] Breast
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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34. Fouda A, Kandil SM, Zalata K, Mansour A, Al-Tonbary Y: Puffiness of the eyelids and lips with multiple subcutaneous masses in 2-month-old infant. Hematol Oncol Stem Cell Ther; 2010;3(4):196-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Puffiness of the eyelids and lips with multiple subcutaneous masses in 2-month-old infant.
  • [MeSH-major] Eyelids / pathology. Lip / pathology. Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Asparaginase / therapeutic use. Common Cold / drug therapy. Daunorubicin / therapeutic use. Female. Humans. Infant. Prednisone / therapeutic use. Subcutaneous Tissue / pathology. Tomography, X-Ray Computed. Vincristine / therapeutic use

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  • (PMID = 21150240.001).
  • [ISSN] 1658-3876
  • [Journal-full-title] Hematology/oncology and stem cell therapy
  • [ISO-abbreviation] Hematol Oncol Stem Cell Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; EC 3.5.1.1 / Asparaginase; VB0R961HZT / Prednisone; ZS7284E0ZP / Daunorubicin; PVDA protocol
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