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Items 1 to 19 of about 19
1. Ogawa S, Fukunaga K, Hiraoka R, Kohda E, Yamaguchi K, Ito D, Hata J: A case of poorly differentiated hilar lung adenocarcinoma of an unidentified histological type. Keio J Med; 2000 Dec;49(4):162-72
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  • [Title] A case of poorly differentiated hilar lung adenocarcinoma of an unidentified histological type.
  • The shadow of a mass was seen at the hilum of the left lung, and the mediastinal lymph nodes on both sides were swollen.
  • No histological diagnosis was obtained even after bronchoscopy, including transbronchial needle aspiration biopsy, but large-cell carcinoma of the lung was diagnosed on the basis of ultrasound-guided biopsy of a shadow in the liver suspected of being a metastatic tumor (T2N3M1, Stage IV).
  • Two courses of chemotherapy (CBCDA + VDS) failed to gain any improvement, and the pain resulting from recurrent bone metastases was managed mainly by the administration of the best supportive care.
  • Autopsy revealed a primary hilar lung tumor with a histological diagnosis of poorly differentiated adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Aged. Bone Neoplasms / secondary. Cell Differentiation. Diagnosis, Differential. Humans. Liver Neoplasms / secondary. Lymphatic Metastasis. Male. Neoplasm Staging. Tomography, X-Ray Computed

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  • (PMID = 11192985.001).
  • [ISSN] 0022-9717
  • [Journal-full-title] The Keio journal of medicine
  • [ISO-abbreviation] Keio J Med
  • [Language] eng
  • [Publication-type] Case Reports; Clinical Conference; Journal Article
  • [Publication-country] Japan
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2. Fujimoto S, Yamaguchi Y, Gotanda H, Shiozawa R, Takemura A, Umeda-Kameyama Y, Yamamoto H, Iijima K, Akishita M, Ouchi Y: [A case of limbic encephalitis with small cell lung carcinoma in which the cognitive function improved and redeteriorated during tumor therapy]. Nihon Ronen Igakkai Zasshi; 2010;47(1):79-85
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  • [Title] [A case of limbic encephalitis with small cell lung carcinoma in which the cognitive function improved and redeteriorated during tumor therapy].
  • A chest X-ray film revealed a mass in the right hilum, while a histological analysis of the biopsied specimen finally established a diagnosis of small cell lung carcinoma.
  • After the 1st course of chemotherapy and whole brain radiation, cognitive function, especially the short-term memory, remarkably improved and the HDS-R score increased to 21/30.
  • However, the tumor again increased in size during the 3(rd) and 4(th) courses of chemotherapy.
  • Interestingly, cognitive function also worsened again and the score of HDS-R declined to 15/30, 20 weeks after the start of chemotherapy.
  • Limbic encephalitis can be associated with malignant tumors, such as small cell lung carcinoma, and some reported cases have shown a cognitive improvement after tumor therapy.
  • [MeSH-major] Cognition Disorders / etiology. Limbic Encephalitis / complications. Lung Neoplasms / complications. Lung Neoplasms / therapy. Small Cell Lung Carcinoma / complications. Small Cell Lung Carcinoma / therapy

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  • (PMID = 20339211.001).
  • [ISSN] 0300-9173
  • [Journal-full-title] Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics
  • [ISO-abbreviation] Nihon Ronen Igakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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3. Yamada N, Okuse C, Nomoto M, Orita M, Katakura Y, Ishii T, Shinmyo T, Osada H, Maeda I, Yotsuyanagi H, Suzuki M, Itoh F: Obstructive jaundice caused by secondary pancreatic tumor from malignant solitary fibrous tumor of pleura: a case report. World J Gastroenterol; 2006 Aug 14;12(30):4922-6
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  • [Title] Obstructive jaundice caused by secondary pancreatic tumor from malignant solitary fibrous tumor of pleura: a case report.
  • A 77-year-old man on systemic chemotherapy against postoperative bilateral multiple lung metastases of malignant solitary fibrous tumor of the pleura suffered from pruritus and jaundice.
  • Abdominal computed tomography showed a tumor with peripheral enhancement in the pancreatic head, accompanied with the dilatation of intra- and extra-hepatic bile ducts.
  • He was diagnosed as having obstructive jaundice caused by a pancreatic head tumor.
  • The pancreatic head tumor was presumably diagnosed as the metastasis of malignant solitary fibrous tumor of the pleura, because the findings on the pancreatic head tumor on abdominal CT were similar to those on the primary lung lesion of malignant solitary fibrous tumor of the pleura.
  • The pancreatic tumor grew rapidly after the implantation of metallic stent in the inferior part of the common bile duct.
  • Autopsy revealed a tumor that spread from the pancreatic head to the hepatic hilum.
  • Immunohistochemically the pancreatic head tumor cells were negative for staining of alpha-smooth muscle actin (alpha-SMA) or CD117, but positive for vimentin, CD34 and CD99.
  • These findings are consistent with those on malignant solitary fibrous tumor of the pleura.
  • We report the first case of obstructive jaundice caused by a secondary pancreatic tumor from malignant solitary fibrous tumor of the pleura.
  • [MeSH-major] Jaundice, Obstructive / etiology. Neoplasms, Fibrous Tissue / pathology. Pancreatic Neoplasms / complications. Pancreatic Neoplasms / secondary. Pleural Neoplasms / pathology
  • [MeSH-minor] Aged. Autopsy. Biomarkers, Tumor / blood. Fatal Outcome. Humans. Male

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  • [Cites] Pathol Int. 2001 Sep;51(9):686-90 [11696171.001]
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  • (PMID = 16937484.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC4087636
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4. Kawahara K, Shiraishi T, Iwasaki A, Yoshinaga Y, Yamamoto S, Yoneda S, Shirakusa T: Thoracoscopic right upper mediastinal dissection for left lung cancer. Jpn J Thorac Cardiovasc Surg; 2002 Oct;50(10):418-23
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  • [Title] Thoracoscopic right upper mediastinal dissection for left lung cancer.
  • OBJECTIVE: In left lung cancer, left and right mediastinum lymphatic spread occur equally frequently.
  • We evaluated the safety and effectiveness of thoracoscopic right upper mediastinal dissection, implemented prior to left lung resection for left lung cancer.
  • METHODS: Between January 1999 and May 2000, 17 patients with left lung cancer underwent thoracoscopic right upper mediastinal dissection prior to resection of the left lung and left mediastinal dissection for left lung cancer.
  • These patients had either enlarged left hilar or bilateral mediastinal nodes, or either a tumor at least 3 cm in diameter or tumor extension to the hilum, mediastinum, or chest wall.
  • Tumor and lymph nodes were examined with hematoxylin and eosin and immunohistochemical staining of cytokeratin for micrometastasis.
  • Postoperative complications occurred in 3 of 4 patients (75%) undergoing induction chemotherapy, but none were lethal.
  • CONCLUSION: Thoracoscopic right upper mediastinal dissection is safe and feasible in treating advanced left lung cancer.
  • [MeSH-major] Lung Neoplasms / surgery. Mediastinum / surgery. Thoracoscopy

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  • (PMID = 12428381.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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5. Nosaka S, Murayama M, Beppu T, Katsuda K, Nakao M, Enomoto M: [Pleomorphic carcinoma of the lung; report of a case]. Kyobu Geka; 2008 Jun;61(6):512-5
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  • [Title] [Pleomorphic carcinoma of the lung; report of a case].
  • Chest radiography and computed tomography (CT) showed a tumor mass near the right hilum and atelectasis of the middle lobe.
  • Bronchoscopy revealed a whitish polypoid tumor obstructing the middle lobe bronchus.
  • Histology by punch biopsy suggested adenocarcinoma Right upper and middle lobectomy was performed, due to the direct invasion of the tumor from the middle lobe to the upper lobe.
  • Histological findings showed adenocarcinoma comprised of spindle cell component, finally diagnosing as pleomorphic carcinoma of the lung.
  • After the operation, systemic chemotherapy, including paclitaxel and carboplatin was performed.
  • [MeSH-major] Carcinoma / surgery. Lung Neoplasms / surgery
  • [MeSH-minor] Aged. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Neoplasms / secondary. Carboplatin / administration & dosage. Chemotherapy, Adjuvant. Fatal Outcome. Female. Humans. Lymph Node Excision. Paclitaxel / administration & dosage. Pneumonectomy. Treatment Outcome

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  • (PMID = 18536305.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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6. Hasturk S, Soylu M, Zeren EH, Hanta I: Basaloid large cell lung carcinoma presenting concurrently with metastatic uveal tumor. Lung Cancer; 2001 Apr;32(1):95-101
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  • [Title] Basaloid large cell lung carcinoma presenting concurrently with metastatic uveal tumor.
  • Chest radiography revealed a left hilar mass and pleural effusion in the left hemithorax.
  • A computed tomography (CT) confirmed the mass in the left hilum and multiple mass lesions consistent with metastasis in the liver and in the body of 12th thoracic vertebra.
  • He died after 4 months with rapid progression of the disease in spite of combined chemotherapy.
  • Although primary lung cancer with concurrent eye metastasis is an uncommon entity, it should always be kept in mind for patients with ocular symptoms.
  • [MeSH-major] Carcinoma, Large Cell / pathology. Carcinoma, Large Cell / secondary. Lung Neoplasms / pathology. Uveal Neoplasms / pathology. Uveal Neoplasms / secondary
  • [MeSH-minor] Carboplatin / therapeutic use. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Paclitaxel / therapeutic use. Pleural Effusion, Malignant / pathology. Smoking / adverse effects. Tomography

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  • (PMID = 11282434.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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7. Kuo SC, Chao Y, Luo JC, Lee KC, Wu CW, Li AF, Lee RC, Li CP: Primary small cell carcinoma of the stomach successfully treated with cisplatin and etoposide. J Chin Med Assoc; 2009 Nov;72(11):598-602
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  • We report a 44-year-old man with primary gastric small cell carcinoma who showed a remarkable response to chemotherapy specific for pulmonary small cell carcinoma.
  • An upper gastrointestinal examination there revealed an ulcerative tumor, 5 cm in diameter, on the lesser curvature side of the cardia, and endoscopic biopsy reported adenocarcinoma.
  • Computed tomography revealed a mass over the lesser curvature of the stomach and some enlarged regional lymph nodes.
  • Pathology revealed gastric mucosa infiltrated by small-sized tumor cells with scanty cytoplasm and hyperchromatic nuclei.
  • Immunohistochemically, the tumor cells were positive for synaptophysin, chromogranin A, and CD56.
  • Follow-up computed tomography showed tumor recurrence with multiple enlarged lymph nodes in the aortocaval region and hepatic hilum.
  • The patient received palliative chemotherapy consisting of cisplatin 80 mg/m(2) on day 1 and etoposide 80 mg/m(2) on days 1-3 every 28 days, and had partial response to the chemotherapy, with a progression-free survival of 10 months.
  • Chemotherapy with cisplatin and etoposide used for small cell carcinoma of the lung is a good treatment for gastric small cell carcinoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Small Cell / drug therapy. Stomach Neoplasms / drug therapy
  • [MeSH-minor] Adult. Cisplatin / administration & dosage. Etoposide / administration & dosage. Humans. Male. Tomography, X-Ray Computed

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  • (PMID = 19948438.001).
  • [ISSN] 1728-7731
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
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8. Yamashita Y, Fujinami K, Hasumi H, Kishida T, Uemura H, Yao M, Noguchi S, Kubota Y: [A case of primary choriocarcinoma of the bladder]. Hinyokika Kiyo; 2004 Apr;50(4):261-4
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  • Cystoscopy revealed a bladder tumor with coagulated blood and necrotic tissue at the dome.
  • We resected the bladder tumor transurethrally.
  • Pathologically, the tumor was shown to be a transitional cell carcinoma with choriocarcinomatous differentiation, G3, > or = pT2.
  • Immunohistochemical staining showed human chorionic gonadotropin (HCG)-positive tumor cells.
  • Pulmonary metastases appeared on a chest X-ray, and combination chemotherapy with cisplatin and etoposide was administered.
  • Although the serum HCG-beta decreased with one course of chemotherapy, it increased immediately thereafter.
  • Lymph node metastases in the pulmonary hilum, mediastinum, and right submaxillary gland were also found.
  • [MeSH-minor] Aged. Chorionic Gonadotropin, beta Subunit, Human / blood. Cystectomy. Humans. Lung Neoplasms / secondary. Male

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  • (PMID = 15188620.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin, beta Subunit, Human
  • [Number-of-references] 12
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9. Yonemori K, Kunitoh H, Sekine I: Small-cell lung cancer with lymphadenopathy in an 18-year-old female nonsmoker. Nat Clin Pract Oncol; 2006 Jul;3(7):399-403; quiz following 403
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  • [Title] Small-cell lung cancer with lymphadenopathy in an 18-year-old female nonsmoker.
  • BACKGROUND: An asymptomatic 18-year-old female presented in December 2002 with a left pulmonary mass, and an enlarged mediastinum and left hilum, detected on a routine chest X-ray.
  • A CT scan of the chest disclosed a round tumor in the left lower lobe and marked enlargement of the ipsilateral hilar and mediastinal lymph nodes.
  • INVESTIGATIONS: CT scan of the chest, routine hematological study, sputum smear and culture for acid-fast bacilli, transbronchial lung biopsy, serum tumor markers, CT scan of the abdomen, MRI scan of the head, bone scintigraphy, lung function tests, blood gas analysis, pathological examination including hematoxylin-eosin staining and immunohistochemistry using chromogranin A, CD56 (neural cell adhesion molecule), and cytokeratin antibodies.
  • DIAGNOSIS: Limited-stage small-cell lung cancer (T1N2M0, clinical stage IIIA).
  • MANAGEMENT: Etoposide plus cisplatin chemotherapy with concurrent accelerated hyperfractionated thoracic radiotherapy, left pneumonectomy and lymph-node dissection.
  • [MeSH-major] Carcinoma, Small Cell. Lung Neoplasms. Lymphatic Diseases
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Diagnosis, Differential. Etoposide / administration & dosage. Female. Humans. Lymph Node Excision. Lymphatic Metastasis. Mediastinal Neoplasms / secondary. Mediastinal Neoplasms / therapy. Neoplasm Staging. Pneumonectomy. Radiotherapy, Adjuvant. Smoking


10. Lin CJ, Perng WC, Chen CW, Lin CK, Su WL, Chian CF: Small cell lung cancer presenting as ectopic ACTH syndrome with hypothyroidism and hypogonadism. Onkologie; 2009 Jul;32(7):427-30
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  • [Title] Small cell lung cancer presenting as ectopic ACTH syndrome with hypothyroidism and hypogonadism.
  • BACKGROUND: Small-cell lung cancer accounts for 15-20% of all lung cancers, and it is the cell type most commonly associated with paraneoplastic syndrome.
  • Small-cell lung cancer presenting as ectopic adrenocorticotropic hormone (ACTH) syndrome associated with hypothyroidism and hypogonadotropic hypogonadism is clinically very rare.
  • CASE REPORT: A 43-year-old man who presented with bilateral lower-extremity edema and hypokalemia had a mass lesion in his left hilum base visible on chest radiograph.
  • Biopsy identified the mass as small-cell lung cancer with focal ACTH staining.
  • RESULTS: Partial remission as evidenced by regression of the tumor mass and return to normal serum cortisol and ACTH levels occurred after the first course of combination chemotherapy using cisplatin and etoposide.
  • An unexpected left-sided spontaneous pneumothorax developed after the first course of chemotherapy and was treated with thoracostomy and a chest tube.
  • The patient developed persistent air leakage and chronic empyema.
  • The treatment of the complicated problems was successful.
  • CONCLUSION: Combination chemotherapy may prove effective in the treatment of small-cell lung cancer with ectopic ACTH syndrome, hypothyroidism and hypogonadism.
  • [MeSH-major] ACTH Syndrome, Ectopic / diagnosis. Hypogonadism / diagnosis. Hypothyroidism / diagnosis. Lung Neoplasms / diagnosis. Small Cell Lung Carcinoma / diagnosis

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19556823.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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11. Nagakawa H, Hiroshima K, Takiguchi Y, Yatomi M, Takahashi Y, Mikami M, Nakatani Y, Kuriyama T: Basaloid squamous-cell carcinoma of the lung in a young woman. Int J Clin Oncol; 2006 Feb;11(1):66-8
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  • [Title] Basaloid squamous-cell carcinoma of the lung in a young woman.
  • We report a rare case of basaloid squamous cell carcinoma of the lung in a young Japanese woman.
  • Chest radiogram and computed tomography (CT) revealed a tumor in the left hilum accompanied by partial atelectasis of the left upper lobe and pleural effusion.
  • Transbronchial fine-needle aspiration cytology supported a tentative diagnosis of primary squamous-cell carcinoma of the lung.
  • Despite a transient response to chemotherapy consisting of carboplatin and paclitaxel, the patient died because of tumor progression 2 months after the start of the chemotherapy.
  • Necropsy established the diagnosis of basaloid squamous-cell carcinoma of the lung.
  • Immunohistochemical studies of the necropsy specimen indicated that the tumor was positive for keratin, vimentin, and S100, and negative for chromogranin A, cytokeratin CAM5.2, and bcl-2.
  • This is the youngest patient with a case of basaloid squamous cell carcinoma of the lung ever reported.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Fatal Outcome. Female. Humans. Neoplasm Staging

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  • (PMID = 16508733.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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12. Infante M, Cariboni U, Alloisio M, Testori A, Cioffi U, Bottoni E: Extended bilateral mediastinal dissection via a limited thoracotomy for right-lung cancer. Minerva Chir; 2006 Apr;61(2):177-80
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  • [Title] Extended bilateral mediastinal dissection via a limited thoracotomy for right-lung cancer.
  • In non small cell lung cancer (NSCLC) patients undergoing surgery after induction chemotherapy, all mediastinal lymphnodes potentially involved by tumor should be resected whenever possible.
  • From the right side, an extensive ipsilateral dissection is feasible through a standard thoracotomy, but contralateral lymphnodes, especially in the left hilum and aortopulmonary window are considered inaccessible.
  • A technical tip is shown to reach and dissect the left paratracheal and aortopulmonary window nodes through a simple right thoracotomy in right-lung cancer.
  • The procedure has been carried out in 3 cases and proved to be technically feasible.
  • The value of such a procedure as to staging accuracy, local disease control and survival should be evaluated in a clinical trial setting.
  • [MeSH-major] Lung Neoplasms / surgery. Lymph Node Excision / methods. Mediastinum / surgery. Pneumonectomy / methods. Thoracotomy / methods

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  • (PMID = 16871151.001).
  • [ISSN] 0026-4733
  • [Journal-full-title] Minerva chirurgica
  • [ISO-abbreviation] Minerva Chir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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13. Kamigaki M, Yamazaki K, Tsujino I, Suga M, Sakaue S, Dosaka-Akita H, Nishimura M: Small cell carcinoma of the lung exclusively localized within the left descending pulmonary artery. Chest; 2005 Jun;127(6):2273-6
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  • [Title] Small cell carcinoma of the lung exclusively localized within the left descending pulmonary artery.
  • A subsequent 2-[18F]fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) scan demonstrated focal uptake in the left hilum.
  • The patient underwent concurrent radiation therapy and chemotherapy with cisplatin and etoposide, resulting in tumor shrinkage and recanalization of the involved PA.
  • This is the first case of small cell carcinoma localized exclusively within the PA, and positive findings on FDG-PET facilitated the unexpected diagnosis.
  • [MeSH-major] Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / therapy. Lung Neoplasms / pathology. Lung Neoplasms / therapy. Pulmonary Artery / pathology
  • [MeSH-minor] Aged. Angiography / methods. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy, Needle. Combined Modality Therapy. Dose Fractionation. Female. Follow-Up Studies. Humans. Immunohistochemistry. Neoplasm Staging. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods. Treatment Outcome

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  • [CommentIn] Chest. 2005 Jun;127(6):1889 [15947298.001]
  • (PMID = 15947349.001).
  • [ISSN] 0012-3692
  • [Journal-full-title] Chest
  • [ISO-abbreviation] Chest
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Nobata K, Fujimura M, Ishiura Y, Shirasaki H, Myou S, Yasui M, Kasahara K, Nonomura A: [A case of adenocarcinoma complicated with massive leukocytosis and hypercalcemia]. Nihon Kokyuki Gakkai Zasshi; 2000 Jul;38(7):530-5
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  • Chest X-ray examination revealed a mass shadow in the right hilum.
  • Transbronchial lung biopsy of the tumor mass yielded a diagnosis of adenocarcinoma.
  • Despite repeated chemotherapy using CDDP and VDS, metastasis to the right adrenal gland and right femur occurred, and was accompanied by hypercalcemia and hypophosphatemia.
  • It appeared that the elevation of G-CSF was induced by IL-6 produced from PTH-rP in cancer tissue.
  • [MeSH-major] Adenocarcinoma / complications. Hypercalcemia / etiology. Leukocytosis / etiology. Lung Neoplasms / complications

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  • (PMID = 11019567.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] JAPAN
  • [Chemical-registry-number] 0 / Parathyroid Hormone; 143011-72-7 / Granulocyte Colony-Stimulating Factor
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15. Kubota T, Daibata M, Kobayashi M, Taguchi H: [A case of pulmonary artery sarcoma successfully treated by total pneumonectomy]. Nihon Kokyuki Gakkai Zasshi; 2007 Jan;45(1):65-70
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

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  • A 39 year-old Japanese man who had been treated for pleuritis developed a tumor in the left lung and was admitted to our hospital.
  • Although evidence of tuberculous pleurisy was not proved medically, he had been treated successfully with antituberculous drugs for 9 months.
  • Two months after completion of antituberculous therapy, his X-ray showed a tumor shadow close to his left hilum.
  • A computed tomography (CT) scan showed a left lung tumor with a diameter of 3.3cm, atelectasis in an ajacent field, and no effusion.
  • Tumor markers targeted for lung cancer remained within normal range.
  • Bronchofiberscopy demonstrated a polypoid tumor from left upper lobe bronchus.
  • The pathological examination of CT guided percutaneous biopsy (CTGB) specimen revealed undifferentiated malignant tumor.
  • He underwent total pneumonectomy of the left lung, and the final pathological diagnosis of pulmonary artery sarcoma was made.
  • He received neither chemotherapy nor radiotherapy.
  • [MeSH-major] Lung Neoplasms / surgery. Pneumonectomy. Pulmonary Artery. Sarcoma / surgery. Vascular Neoplasms / surgery
  • [MeSH-minor] Adult. Humans. Male. Pleural Effusion, Malignant / etiology. Prognosis. Radiography, Thoracic. Survivors. Tomography, X-Ray Computed

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  • (PMID = 17313030.001).
  • [ISSN] 1343-3490
  • [Journal-full-title] Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society
  • [ISO-abbreviation] Nihon Kokyuki Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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16. Hagiuda J, Matsumoto M, Hanawa Y, Ishikawa H, Marumo K: [Adenocarcinoma of the rete testis. A case report]. Nihon Hinyokika Gakkai Zasshi; 2010 Nov;101(7):749-53
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  • Adenocarcinoma of the rete testis is a rare malignant tumor with a poor prognosis.
  • The diagnosis is often difficult and made incidentally.
  • Positron emission tomography (PET) was performed in another hospital, and the patient was referred for a left testicular tumor, multiple lung metastases, and para-aorta lymph node metastasis.
  • Pathological examination revealed a hard whitish mass around the testis involving the epididymis and tunica vaginalis and spreading under the subcutaneous tissue.
  • Histological examination revealed adenocarcinoma in the hilum of the testis, which extended to the subcutaneous tissue but not to the surface of the scrotum.
  • After the histological diagnosis of adenocarcinoma of the rete testis was confirmed, computed tomography (CT) was performed and showed multiple pulmonary nodules and para-aortica lymph node swelling of 3 cm diameter.
  • Because the patient did not wish to receive chemotherapy or other aggressive treatment, he has been followed-up with palliative care since his diagnosis.
  • Although local recurrence has occurred 4 months later, he is still alive for 8 months since his diagnosis.
  • [MeSH-major] Adenocarcinoma / therapy. Testicular Neoplasms / therapy
  • [MeSH-minor] Aged, 80 and over. Humans. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Lymphatic Metastasis. Magnetic Resonance Imaging. Male. Orchiectomy. Palliative Care. Positron-Emission Tomography. Tomography, X-Ray Computed

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  • (PMID = 21174741.001).
  • [ISSN] 0021-5287
  • [Journal-full-title] Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology
  • [ISO-abbreviation] Nippon Hinyokika Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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17. Gironet N, De Muret A, Machet L, Diot P, Rivollier C, Dumont P, Lorette G, Vaillant L: [Paraneoplastic pemphigus revealing dendritic cell sarcoma originating from Castleman's disease of the neck]. Ann Dermatol Venereol; 2005 Jan;132(1):41-4
MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.

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  • The pemphigus was manifested by the most unusual, exclusive, involvement of the mucosa of the mouth and lung.
  • The search for intercellular anti-substance antibodies on rat spleen was positive, corresponding to anti-envoplakin IgG and leading to the diagnosis of paraneoplastic pemphigus.
  • The thoracic x-ray and scan revealed a hilum tumor, the histological examination of which confirmed the diagnosis of Castleman's disease concomitant to sarcomatous transformation.
  • Following surgical treatment, the respiratory failure worsened.
  • The patient improved with systemic corticosteroids at the dose of 2 mg/kg/d and chemotherapy was initiated.
  • The transformation of the Castleman tumor into a sarcoma may have unmasked intra-cellular antigens (plakins), initiating the specific immune reaction.
  • [MeSH-minor] Adrenal Cortex Hormones / therapeutic use. Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cell Transformation, Neoplastic. Dendritic Cells. Diagnosis, Differential. Fatal Outcome. Humans. Male. Oral Ulcer / etiology. Oral Ulcer / pathology. Respiratory Insufficiency

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  • (PMID = 15746607.001).
  • [ISSN] 0151-9638
  • [Journal-full-title] Annales de dermatologie et de vénéréologie
  • [ISO-abbreviation] Ann Dermatol Venereol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones
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18. Kubota T, Ikezoe T, Harada R, Nakata H, Kobayashi M, Taguchi H: [Pancreatic metastasis from lung cancer: report of an autopsy case]. Nihon Kokyuki Gakkai Zasshi; 2003 Dec;41(12):917-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pancreatic metastasis from lung cancer: report of an autopsy case].
  • A 69 year-old man with abnormal lung shadows in the right lung field was admitted to our hospital.
  • A chest computed tomography (CT) scan showed a lung tumor with hilar and mediastinal lymph node swelling.
  • A CT scan of the abdomen demonstrated a solitary pancreatic head tumor with a diameter of 3 cm.
  • Pathological examination of a transbronchial biopsy specimen revealed squamous cell carcinoma (SCC) of the lung.
  • Since obstructive jaundice had progressed rapidly, the patient received endoscopic nasobiliary drainage (ENBD) and stent-drainage therapy prior to chemotherapy using gemcitabine.
  • An autopsy was performed, and microscopic and immunohistochemical examination revealed that the pancreatic tumor was a metastasis from lung cancer.
  • To our knowledge, obstructive jaundice due to pancreatic metastasis from lung SCC, especially that preceding the advent of a clinical manifestation of primary lung cancer, has rarely been reported.
  • [MeSH-major] Carcinoma, Small Cell / secondary. Jaundice, Obstructive / pathology. Lung Neoplasms / pathology. Pancreatic Neoplasms / secondary


19. Kawashima S, Okita K, Yamawaki T, Matsukawa N, Ojika K: [Case of paraneoplastic limbic encephalitis associated with malignant B cell lymphoma]. Brain Nerve; 2009 Feb;61(2):208-12
MedlinePlus Health Information. consumer health - Brain Tumors.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chest computed tomography (CT) revealed a mass lesion on the right hilum of the lung.
  • Therefore, tumor resection was performed.
  • The pathological diagnosis was diffuse large B cell lymphoma.
  • Chemotherapy was performed, but the patient's clinical symptoms failed to improve.
  • We suggest that an early diagnosis of paraneoplastic limbic encephalitis with progressive symptoms such as changes in characteristics is important.
  • Early diagnosis and treatment of malignant tumors is desirable to facilitate clinical recovery and improve prognosis.
  • [MeSH-minor] Autoantibodies. Cognition Disorders / etiology. Combined Modality Therapy. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Receptors, Glutamate / immunology. Weight Gain

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  • (PMID = 19235472.001).
  • [ISSN] 1881-6096
  • [Journal-full-title] Brain and nerve = Shinkei kenkyū no shinpo
  • [ISO-abbreviation] Brain Nerve
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Receptors, Glutamate
  • [Number-of-references] 10
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