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1. Takemoto Y, Kawahara M, Yamamoto S, Iuchi K, Mori T, Ueda E, Tsuchiyama T, Furuse K: Synchronous primary adenocarcinoma of the lung and leiomyosarcoma of the small intestine. Intern Med; 2000 Aug;39(8):655-8
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  • [Title] Synchronous primary adenocarcinoma of the lung and leiomyosarcoma of the small intestine.
  • The occurrence of synchronous epithelial cancer of the lung and leiomyosarcoma of the small intestine is rare.
  • We report here the case of a 62-year-old man with adenocarcinoma of the lung in clinical stage IIIB (T4N0M0).
  • After two courses of chemotherapy (cisplatin, 80 mg/m2 and mitomycin C, 8 mg/m2) the patient developed symptoms of a small bowel obstruction.
  • Palliative surgical resection was performed and a leiomyosarcoma of the small intestine was found and defined by an immunohistological study.
  • The patient died of disseminated adenocarcinoma 26 months following chemotherapy.
  • [MeSH-major] Adenocarcinoma / pathology. Intestinal Neoplasms / pathology. Leiomyosarcoma / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 10939541.001).
  • [ISSN] 0918-2918
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] JAPAN
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2. Hayashi T, Tagawa T, Ashizawa K, Abe K, Kinoshita N, Tsutsui S, Anami M, Nagayasu T: Contrast-enhanced dynamic magnetic resonance imaging of primary pulmonary leiomyosarcoma. Tohoku J Exp Med; 2006 Nov;210(3):263-7
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  • [Title] Contrast-enhanced dynamic magnetic resonance imaging of primary pulmonary leiomyosarcoma.
  • Chest computed tomography (CT) revealed a 55 x 40 mm well-defined mass with smooth margins in the lower lobe of the right lung (S6).
  • However, contrast-enhanced dynamic magnetic resonance imaging (MRI) revealed enhancement of the lesion, which had a clear margin and homogenous consistency, suggesting a benign pulmonary solid tumor.
  • The lesion was accordingly diagnosed as leiomyosarcoma with low grade malignancy, and right lower lobectomy was performed.
  • The patient has remained free from recurrence for 18 months without any additional chemotherapy or radiation therapy.
  • Contrast-enhanced dynamic MRI should be carried out to facilitate accurate preoperative diagnosis and selection of the correct surgical plan.
  • [MeSH-major] Contrast Media / pharmacology. Leiomyosarcoma / diagnosis. Leiomyosarcoma / pathology. Lung Neoplasms / diagnosis. Lung Neoplasms / pathology. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adult. Humans. Immunohistochemistry. Lung / pathology. Male. Radiography, Thoracic / methods. Thoracic Surgery, Video-Assisted. Tomography, X-Ray Computed / methods

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  • (PMID = 17077604.001).
  • [ISSN] 0040-8727
  • [Journal-full-title] The Tohoku journal of experimental medicine
  • [ISO-abbreviation] Tohoku J. Exp. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media
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3. Kitsukawa S, Samejimai T, Noda K, Ito T, Furukawa K, Saito M: [A case of leiomyosarcoma of the scrotum: chemotherapy with anti-cancer agents was effective for the lung metastasis]. Hinyokika Kiyo; 2006 Sep;52(9):737-40
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  • [Title] [A case of leiomyosarcoma of the scrotum: chemotherapy with anti-cancer agents was effective for the lung metastasis].
  • Lung tumors were found 20 months after resection of the origin.
  • Systemic chemotherapy with new anti-cancer agents (Paclitaxel and Gemcitabine) was performed.
  • The main tumor was reduced to 56% in its diameter after 6 courses of chemotherapy.
  • Exclusion of the right middle and lower pulmonary lobe was performed.
  • The final pathological diagnosis of the lung tumor was metastatic liposarcoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Genital Neoplasms, Male / drug therapy. Leiomyosarcoma / drug therapy. Leiomyosarcoma / secondary. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Scrotum
  • [MeSH-minor] Combined Modality Therapy. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Drug Administration Schedule. Humans. Male. Middle Aged. Paclitaxel / administration & dosage. Pneumonectomy

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  • (PMID = 17040063.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0W860991D6 / Deoxycytidine; B76N6SBZ8R / gemcitabine; P88XT4IS4D / Paclitaxel
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4. Moreno Antón F, Casado Herraez A, Puente Vázquez J, Gómez Díaz R, Aragoncillo P, Díaz-Rubio García E: Cardiac metastasis from uterine leiomyosarcoma. Clin Transl Oncol; 2006 May;8(5):375-8
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  • [Title] Cardiac metastasis from uterine leiomyosarcoma.
  • We report the case of a patient who presented with heart metastasis 6 years after resection of an uterine leiomyosarcoma.
  • Although cardiac metastases from uterine leiomyosarcoma are exceptional, they should be suspected in the presence of suggestive symptoms, since they can be associated with long survival after surgical treatment.
  • [MeSH-major] Heart Neoplasms / secondary. Leiomyosarcoma / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Combined Modality Therapy. Dacarbazine / administration & dosage. Dacarbazine / analogs & derivatives. Deoxycytidine / administration & dosage. Deoxycytidine / analogs & derivatives. Diagnostic Errors. Doxorubicin / administration & dosage. Fatal Outcome. Female. Humans. Hysterectomy. Ifosfamide / administration & dosage. Kidney Neoplasms / drug therapy. Kidney Neoplasms / secondary. Kidney Neoplasms / surgery. Leiomyoma / diagnosis. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Middle Aged. Ovariectomy. Taxoids / administration & dosage. Thoracic Surgery, Video-Assisted

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  • (PMID = 16760015.001).
  • [ISSN] 1699-048X
  • [Journal-full-title] Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
  • [ISO-abbreviation] Clin Transl Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Taxoids; 0W860991D6 / Deoxycytidine; 15H5577CQD / docetaxel; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; B76N6SBZ8R / gemcitabine; UM20QQM95Y / Ifosfamide; YF1K15M17Y / temozolomide
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5. Penel N, Italiano A, Isambert N, Bompas E, Bousquet G, Duffaud F, French Sarcoma Group (Groupe Sarcome Français/Groupe d'Etude des Tumeurs Osseuses): Factors affecting the outcome of patients with metastatic leiomyosarcoma treated with doxorubicin-containing chemotherapy. Ann Oncol; 2010 Jun;21(6):1361-5
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  • [Title] Factors affecting the outcome of patients with metastatic leiomyosarcoma treated with doxorubicin-containing chemotherapy.
  • BACKGROUND: To determine whether pulmonary metastasectomy or the addition of ifosfamide/dacarbazine to a doxorubicin-containing regimen offers a survival benefit to adult patients with metastatic leiomyosarcoma.
  • The sole identified prognostic factor for OS was the interval between initial diagnosis and metastatic relapse.


6. Nishida T, Shoji S, Itoh T, Minami H, Akizuki K, Ozuno I, Kageyama H, Ozaki I, Yamamoto K, Yamamoto A, Nishiyama N: [Metastatic lung tumor from uterine leiomyosarcoma]. Kyobu Geka; 2006 Dec;59(13):1191-6
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  • [Title] [Metastatic lung tumor from uterine leiomyosarcoma].
  • We herein present 2 cases of metastatic lung tumor derived from uterine leiomyosarcoma.
  • She had undergone hysterectomy and oophorectomy for uterine leiomyosarcoma 19 months previously.
  • A round 3 cm mass in the right lung (S10) was seen on chest X-ray and computed tomography (CT).
  • No other distant metastases or local recurrence were found, and the right lower lobectomy was perfomed under the clinical diagnosis of metastatic lung tumor.
  • Postoperative pathologic examination revealed the tumor as a metastatic leiomyosarcoma.
  • The patient recovered uneventfully, and there have been no signs of recurrence for 26 months after the pulmonary resection.
  • In the case 2, a 58-year-old woman, who had undergone hysterectomy and oophorectomy for uterine leiomyosarcoma 7 months previously, was admitted to our hospital for further examination of pulmonary tumors on chest X-ray.
  • Two tumors were recognized in the left lung (S8 and S10) on chest X-ray and CT.
  • No other distant metastases or local recurrence were found, and the left lower lobectomy was performed under the clinical diagnosis of metastatic lung tumors.
  • The tumors proved to be lung metastases derived from uterine leiomyosarcoma.
  • However, brain metastasis was found 1 month after the pulmonary resection, and she underwent resection of brain metastasis.
  • Two months after the brain metastasectomy, local recurrence of the brain tumor developed and re-resection followed by stereotactic radiotherapy was performed.
  • Furthermore, intrapelvic recurrence was found 4 months after the pulmonary resection.
  • Exploratory laparotomy revealed the tumor was unresectable, and she received 4 courses of chemotherapy (paclitaxel and carboplatin).
  • For metastatic lung tumor from uterine leiomyosarcoma, surgery has been considered the best choice.
  • However, for patients with uterine leiomyosarcoma who cannot be treated surgically because of multiple metastatic tumors or poor surgical risk chemotherapy (paclitaxel and carboplatin) or stereotactic radiotherapy can be strategies.
  • [MeSH-major] Leiomyosarcoma / secondary. Leiomyosarcoma / surgery. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Uterine Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brain Neoplasms / secondary. Brain Neoplasms / surgery. Carboplatin / administration & dosage. Combined Modality Therapy. Female. Humans. Middle Aged. Neoplasm Recurrence, Local. Paclitaxel / administration & dosage. Pneumonectomy

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  • (PMID = 17163213.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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7. Mayer F, Aebert H, Rudert M, Königsrainer A, Horger M, Kanz L, Bamberg M, Ziemer G, Hartmann JT: Primary malignant sarcomas of the heart and great vessels in adult patients--a single-center experience. Oncologist; 2007 Sep;12(9):1134-42
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  • RESULTS: Tumors were located in the left ventricle (n = 3), left/right atrium (n = 2/3), pulmonary artery (n = 2), and ventricular septum, aorta, pericardium, and inferior vena cava (n = 1 each).
  • The most frequently encountered histologic subtypes were leiomyosarcoma and angiosarcoma.
  • Of those, two developed local recurrence within 2 and 10 months from surgery.
  • Eleven patients received palliative chemotherapy, seven of those as initial treatment.
  • Eight patients attained a response to treatment, two had disease stabilization for 6 and 12 months.
  • After a median follow-up of 14.5 months (range, 2-156), three patients were alive with no evidence of disease 11, 52, and 156 months after diagnosis.
  • Given the promising response to chemotherapy, an optimized treatment approach including neoadjuvant chemo-/radiotherapy in patients with locally advanced disease should be pursued.
  • [MeSH-minor] Adult. Aortic Diseases / epidemiology. Female. Follow-Up Studies. Germany / epidemiology. Hemangiosarcoma / epidemiology. Humans. Leiomyosarcoma / epidemiology. Lung Neoplasms / secondary. Lymphatic Metastasis. Male. Middle Aged. Neoadjuvant Therapy / statistics & numerical data. Pulmonary Artery / pathology. Remission Induction. Retrospective Studies. Survival Rate. Venae Cavae / pathology

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  • (PMID = 17914083.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Nassar OA, Abdul Moaty SB, Khalil el-SA, El-Taher MM, El Najjar M: Outcome and prognostic factors of uterine sarcoma in 59 patients: single institutional results. J Egypt Natl Canc Inst; 2010 Jun;22(2):113-22

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: Uterine corpus sarcomas are rare heterogeneous tumors characterized by rapid progression and poor response to treatment.
  • This series investigated treatment options, relapse pattern, survival and prognostic factors.
  • Leiomyosarcoma accounted for 42.2% followed by carcinosarcoma (35.5%) and endometrial stromal sarcoma (18.6%).
  • Surgery was the primary line of treatment for all cases with total abdominal hysterectomy and bilateral salpingoophorectomy in 88% of cases and 12% had less extensive surgery.
  • Twenty-four (40.7%) patients had surgery alone, 24 (40.7%) had surgery and radiotherapy, 7 (11.9%) had surgery and chemo-irradiation and 4 (6.7%) had surgery and chemotherapy.
  • Neither extent of surgery, chemotherapy, histologic type or grade had significant effect on survival.
  • Adjuvant radiotherapy offered 62% 2-year cumulative overall survival versus 22% for surgery alone and surgery with chemotherapy.
  • Salvage surgery for isolated relapses was performed for 9/32 recurrent patients (28%) including 5 lung metastatectomies and 4 local pelvic resections.
  • Mean survival after pulmonary resections was 7.4 months (6-14).
  • CONCLUSION: Diagnosis of uterine sarcoma is in itself a poor prognostic factor.
  • KEY WORDS: Uterine cancer - Uterine sarcoma - Uterine sarcoma treatment - Sarcoma irradiation - Sarcoma prognosis.

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  • (PMID = 21860468.001).
  • [ISSN] 1110-0362
  • [Journal-full-title] Journal of the Egyptian National Cancer Institute
  • [ISO-abbreviation] J Egypt Natl Canc Inst
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
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9. Ueda T, Emoto M, Fukuoka M, Miyahara D, Horiuchi S, Tsujioka H, Kawarabayashi T: Primary leiomyosarcoma of the fallopian tube. Int J Clin Oncol; 2010 Apr;15(2):206-9
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  • [Title] Primary leiomyosarcoma of the fallopian tube.
  • We report the case of a 69-year-old woman affected with leiomyosarcoma of the left fallopian tube.
  • The preoperative diagnosis was a left adnexal malignant tumor based on pelvic examination, abdominal computed tomography, and magnetic resonance imaging.
  • Following a laparotomy, she was ultimately diagnosed with a FIGO IIc fallopian tube leiomyosarcoma.
  • The patient subsequently received adjuvant chemotherapy with pirarubicin and ifosfamide.
  • Thirty months after the first therapy, a computed tomography scan revealed metastasis of the liver, lung, and supraclavicular lymph node.
  • The patient died of the disease 39 months after the initial treatment.
  • [MeSH-major] Fallopian Tube Neoplasms / diagnosis. Leiomyosarcoma / diagnosis
  • [MeSH-minor] Aged. Biopsy. Chemotherapy, Adjuvant. Fatal Outcome. Female. Humans. Hysterectomy. Liver Neoplasms / secondary. Lung Neoplasms / secondary. Lymph Node Excision. Lymphatic Metastasis. Magnetic Resonance Imaging. Omentum / surgery. Ovariectomy. Rectum / pathology. Rectum / surgery. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20191300.001).
  • [ISSN] 1437-7772
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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10. Nicòtina PA, Antico F, Caruso C, Triolo O: Primary ovarian leiomyosarcoma. Proliferation rate and survival. Eur J Gynaecol Oncol; 2004;25(4):515-6
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  • [Title] Primary ovarian leiomyosarcoma. Proliferation rate and survival.
  • OBJECTIVE: A case of Stage IIA primary ovarian leiomyosarcoma (LMS) with an unfavorable outcome 24 months after total abdominal hysterectomy with bilateral salpingo-oophorectomy, despite chemotherapy treatment, is described.
  • Eighteen months from surgery the patient showed peritoneal spreading with ascites, liver and lung metastases.
  • Immunohistology was also carried out to reveal some intermediate-type filamentous proteins, as histogenetic markers, and the MIB1 monoclonal antibody was used to assess the percent of MIB1-positive nuclei (MIB1 labeling index).
  • RESULTS: The histologic findings and immunohistology of the assayed intermediate filamentous proteins substantiated a diagnosis of LMS, with associated coagulation necrosis and not rare mitotic figures.
  • [MeSH-major] Leiomyosarcoma / pathology. Leiomyosarcoma / surgery. Neoplasm Invasiveness / pathology. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery

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  • (PMID = 15285319.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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11. Wrede J, Völcker HE, Dithmar S: [Subcutaneous leiomyosarcoma metastatic to the eyelid]. Ophthalmologe; 2007 Jan;104(1):66-8
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  • [Title] [Subcutaneous leiomyosarcoma metastatic to the eyelid].
  • Leiomyosarcomas are soft tissue sarcomas arising most commonly in the uterus and gastrointestinal tract, whereas dermal leiomyosarcomas are less frequent.
  • A subcutaneous leiomyosarcoma of the neck had been excised 21 months before with subsequent radiotherapy.
  • Seven months later metastases to the lung, liver, and left upper arm were detected.
  • The patient received chemotherapy.
  • The prognosis of cutaneous/subcutaneous leiomyosarcoma correlates with the depth of the tumor.
  • To our knowledge this is the first presentation of a subcutaneous leiomyosarcoma metastatic to the eyelid.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Eyelid Neoplasms / secondary. Leiomyosarcoma / diagnosis. Leiomyosarcoma / secondary. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary
  • [MeSH-minor] Adult. Female. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / surgery. Humans. Treatment Outcome

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  • (PMID = 16132990.001).
  • [ISSN] 0941-293X
  • [Journal-full-title] Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
  • [ISO-abbreviation] Ophthalmologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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12. Lai DS, Lue KH, Su JM, Chang H: Primary bronchopulmonary leiomyosarcoma of the left main bronchus in a child presenting with wheezing and atelectasis of the left lung. Pediatr Pulmonol; 2002 Apr;33(4):318-21
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  • [Title] Primary bronchopulmonary leiomyosarcoma of the left main bronchus in a child presenting with wheezing and atelectasis of the left lung.
  • Primary lung tumors are rare in children, and primary bronchopulmonary leiomyosarcomas are very rare in children, with only 10 cases reported in the English-language literature.
  • We report on the eleventh case of primary bronchopulmonary leiomyosarcoma in a child, and it is the first case in Taiwan, and also in Asia.
  • Chest roentgenogram and bronchoscopy are helpful in the diagnosis of primary bronchopulmonary tumors, but a definitive diagnosis can only be made by biopsy.
  • The tumor is potentially curable if total excision is possible; irradiation has little therapeutic value, and early excision offers the only hope of cure.
  • The child is alive and well 19 months after pneumonectomy, without having received radiotherapy or chemotherapy.
  • [MeSH-major] Leiomyosarcoma / diagnosis. Lung Neoplasms / diagnosis. Pulmonary Atelectasis / etiology
  • [MeSH-minor] Asthma / diagnosis. Child. Diagnosis, Differential. Humans. Male. Pneumonectomy. Respiratory Sounds / etiology

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  • [Copyright] Copyright 2002 Wiley-Liss, Inc.
  • (PMID = 11921463.001).
  • [ISSN] 8755-6863
  • [Journal-full-title] Pediatric pulmonology
  • [ISO-abbreviation] Pediatr. Pulmonol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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13. Indelicato DJ, Keole SR, Shahlaee AH, Morris CG, Gibbs CP, Scarborough MT, Islam S, Marcus RB: Ewing tumors of the chest wall: Local control and long-term outcomes. J Clin Oncol; 2009 May 20;27(15_suppl):e21501

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  • : e21501 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • Neoadjuvant chemotherapy was performed in 4 cases (3 resected).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Surgical resection is the fundamental therapy, but in the future the role of neoadjuvant CT will increase.

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  • (PMID = 27963390.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Comandone A, Boglione A, Pochettino P, Berno E, Inguì M, Papotti M, Borasio P, Maggi G, Brach Del Prever E, Gino G: Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas. J Clin Oncol; 2009 May 20;27(15_suppl):e21509

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary sarcomas of the lungs and mediastinum: Clinicopathological study and therapy results of Piedmontese Group for Sarcomas.
  • : e21509 Background: Primary sarcomas of the lungs and mediastinum are rare and few data are reported on treatment and results of therapy.
  • Pts characteristics: median age 41 (19-80 y), male/female 19/12; symptoms at diagnosis: dyspnoea (42%), chest and shoulder pain (39%), cough (35%), hemophtoae (13%), discomfort (10%).
  • 26 lung sarcomas presented as a singular mass in 23 cases and as a metastatic disease in 3.
  • RESULTS: In 20/31 cases the tumour was immediately resected (3 mediastinal masses and 17 lung sarcomas).
  • Neoadjuvant chemotherapy was performed in 4 cases (3 resected).
  • The histology were: peripheral nerve tumour 7, leiomyosarcoma 4, MFH 2, fibrosarcoma 2, liposarcoma 1, angiosarcoma 2, undifferentiated sarcoma 1, solitary fibrous tumour 2, rhabdomyosarcoma 2, synovialsarcoma 2, pulmonary artery sarcoma 1, pleuropolmonary blastoma 1, malignant hemangiopericytoma 1, mixoid chondrosarcoma 1, ectopic osteosarcoma 1, aggressive fibromatosis 1.
  • Only 4 pts received neoadjuvant chemotherapy, 11 adjuvant CT, 5 exclusive CT + RT for inoperable disease.
  • Surgical resection is the fundamental therapy, but in the future the role of neoadjuvant CT will increase.

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  • (PMID = 27963441.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Penel N, Italiano A, Isambert N, Bompas E, Bousquet G, Bousquet G, Duffaud F: Effect of metastasectomy and doxorubicin dose on the outcome of patients with metastastic leiomyosarcoma: A multicenter study. J Clin Oncol; 2009 May 20;27(15_suppl):10580

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of metastasectomy and doxorubicin dose on the outcome of patients with metastastic leiomyosarcoma: A multicenter study.
  • : 10580 Background: The role of metastasectomy and front-line chemotherapy modalities remain debated in the metastastatic soft tissue sarcoma setting.
  • The respective impact of treatment modalities on PFS and OS were assessed after adjustment to prognostic factors.
  • RESULTS: This database included 46 (31%) uterus and 101 soft-tissues (69%) M-LMS.
  • After front-line chemotherapy, 36 patients with lung metastasis (24%) underwent subsequent complete metastasectomy.
  • The univariate analysis identified the following prognostic factors for PFS: performance status (PS), grade, presence of liver or lung metastases.
  • Only one treatment parameter was associated with better PFS: planned doxorubicin dose superior to 60 mg/m<sup>2</sup>/3 weeks (HR=7.57 [1.32-10.40], p=0.023).
  • The univariate analysis identified the following prognostic factors: PS, time interval between diagnosis and metastatic relapse, local relapse and grade.
  • Under multivariate analysis, there was only one good prognostic factor for PFS: interval time between initial diagnosis and metastasis > 12 months (p=0.006).
  • Other chemotherapy parameters did not significantly modify OS.
  • CONCLUSIONS: Doxorubicin dose and metastasectomy remain the cornerstone of the optimal treatment of M-LMS.

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  • (PMID = 27963870.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Murakami M, Tsukada H, Ikeda M, Watanabe M, Muramatsu T, Miyamoto T, Makino T, Yasuda S, Ide M, Nasu S: Availability of whole-body positron emission tomography (PET) for the detection of metastatic sites in recurrent uterine sarcoma. J Clin Oncol; 2004 Jul 15;22(14_suppl):5100

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Availability of whole-body positron emission tomography (PET) for the detection of metastatic sites in recurrent uterine sarcoma.
  • Accurate diagnosis of the metastatic sites is important for the treatment strategy.
  • Unfortunately current diagnostic techniques, including CT, MRI, and ultrasonography (US) are not efficient for the detection of recurrence.
  • There is little report of the experience with whole-body 18 fluorodeoxyglucose (FDG)-PET for the detection of recurrence in the follow up of patients with uterine sarcomas.
  • The purpose of this study is to evaluate the availability of FDG-PET for the detection of recurrence in patients with uterine sarcomas.
  • METHODS: Twelve patients with pathologically proven uterine sarcomas (nine leiomyosarcoma and three carcinosarcoma) took FDG-PET, CT, MRI and US for the purpose of the detection of recurrence after the primary treatment.
  • RESULTS: The final diagnoses of recurrence were established in five cases (three carcinosarcoma and two leiomyosarcoma).
  • PET scan showed all recurrent sites of intraperitoneum, liver, lung and retroperitoneal lymph nodes.
  • Positive results of PET scan did not affect the prognosis in four patients, but another patient with solitary intraperitoneal tumor by PET scan could received the chemotherapy and operation, which histologically confirmed the recurrence of leiomyosarcoma.
  • Application of PET scan for the early detection of recurrence may affect the prognosis of some patients with uterine sarcoma.

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  • (PMID = 28015696.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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17. Cautero N, De Luca S, Vecchi A, Garelli P, Nicolini D, Martorelli G, Frascà GM, Gaffi G, Taruscia D, Bearzi I, Adani G, Risaliti A: Peritoneal leiomyosarcoma in a kidney transplant patient: a case report. Transplant Proc; 2007 Jul-Aug;39(6):2038-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peritoneal leiomyosarcoma in a kidney transplant patient: a case report.
  • Our present report focused on a 46-year-old woman who received immunosuppressive therapy based on cyclosporine and steroids for renal transplantation.
  • Eight years after transplantations, she suffered lower abdominal pain and a mass involving peritoneal soft tissues was located near the right iliac vessels.
  • Upon radical tumor excision, the histological examination revealed a high-grade leiomyosarcoma.
  • After 30 days, a computed tomography scan revealed two small pulmonary metastases, so the patient received adriamycin.
  • Six months after the diagnosis, there was no intra-abdominal relapse and the pulmonary metastasis remain stable.
  • The function of the transplanted kidney was normal and the patient was listed for laparoscopic pulmonary resection.
  • Sarcomas in solid organ transplant patients appear to have aggressive features with 62% being high grade and 40% metastatic at the time of primary diagnosis with a recurrence rate of 30% and a 5-year survival rate of 25%.
  • Patients diagnosed with sarcoma should be treated with multimodality therapy.
  • After aggressive surgery whenever possible, a combination of a traditional cytotoxic drug and a "signal" blocking agent like rapamycin may increase selectivity toward tumor cells.
  • [MeSH-major] Kidney Transplantation. Leiomyosarcoma / diagnosis. Peritoneal Neoplasms / diagnosis. Sirolimus / therapeutic use
  • [MeSH-minor] Female. Humans. Immunosuppressive Agents / therapeutic use. Lung Neoplasms / pathology. Middle Aged. Neoplasm Metastasis. Postoperative Complications / diagnosis. Postoperative Complications / radiography. Tomography, X-Ray Computed

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  • (PMID = 17692686.001).
  • [ISSN] 0041-1345
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; W36ZG6FT64 / Sirolimus
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18. Sandruck J, Escobar P, Lurain J, Fishman D: Uterine leiomyosarcoma metastatic to the sphenoid sinus: a case report and review of the literature. Gynecol Oncol; 2004 Feb;92(2):701-4
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  • [Title] Uterine leiomyosarcoma metastatic to the sphenoid sinus: a case report and review of the literature.
  • BACKGROUND: Leiomyosarcoma (LMS) of the uterus is a rare neoplasm with an aggressive growth pattern.
  • The most common sites of recurrent disease are lung, liver, and peritoneal cavity.
  • CASE: A 39-year-old woman underwent a total abdominal hysterectomy, bilateral salpingo-oophorectomy, pelvic and paraaortic lymph node biopsies, omentectomy, and appendectomy for Grade 2 FIGO Stage 1 uterine leiomyosarcoma.
  • She underwent incomplete resection of the recurrence and was treated postoperatively with adjuvant MAID chemotherapy with poor response.
  • Five months later, she was treated with radiation therapy to the base of the skull with no response.
  • She expired from the disease 13 months after the diagnosis of the recurrence.
  • The treatment options are limited.
  • Surgical management should be considered as uterine LMS has a low response to chemotherapy and surgical resection of LMS to sites such as lung and abdomen has been suggested to offer a benefit.
  • Radiation therapy may provide palliative benefit in the setting of metastatic disease.
  • [MeSH-major] Leiomyosarcoma / pathology. Leiomyosarcoma / secondary. Paranasal Sinus Neoplasms / secondary. Sphenoid Sinus. Uterine Neoplasms / pathology

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  • (PMID = 14766270.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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19. Ethunandan M, Stokes C, Higgins B, Spedding A, Way C, Brennan P: Primary oral leiomyosarcoma: a clinico-pathologic study and analysis of prognostic factors. Int J Oral Maxillofac Surg; 2007 May;36(5):409-16
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  • [Title] Primary oral leiomyosarcoma: a clinico-pathologic study and analysis of prognostic factors.
  • The demographic details, clinical presentation, diagnosis, treatment and outcome were documented for the whole group and clinico-pathologic variables analysed to detect potential prognostic factors.
  • Surgical excision was most commonly employed with radiotherapy and chemotherapy being reserved for recurrent and metastatic tumours.
  • [MeSH-major] Leiomyosarcoma / pathology. Mouth Neoplasms / pathology
  • [MeSH-minor] Age Factors. Aged. Aged, 80 and over. Female. Humans. Lung Neoplasms / secondary. Lymphatic Metastasis / pathology. Male. Mandibular Neoplasms / pathology. Maxillary Neoplasms / pathology. Middle Aged. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / radiotherapy. Prognosis. Retrospective Studies. Sex Factors. Survival Rate. Tongue Neoplasms / pathology

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  • (PMID = 17395428.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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20. Steurer S, Huber M, Lintner F: Dedifferentiated chondrosarcoma of the lung: case report and review of the literature. Clin Lung Cancer; 2007 Jul;8(7):439-42
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  • [Title] Dedifferentiated chondrosarcoma of the lung: case report and review of the literature.
  • We report on a case of a 49-year-old woman who presented with a round focus in the upper lobe of the left lung.
  • The performed biopsy showed features of a leiomyosarcoma.
  • After chemotherapy and consecutive tumor resection, the histologic investigation of the entire tumor mass revealed a dedifferentiated chondrosarcoma.
  • Careful clinical and radiologic examinations showed no evidence of further pulmonary and extra-pulmonary tumor lesions.
  • The final diagnosis of a primary dedifferentiated chondrosarcoma of the lung was based on the morphologic criteria and review of the literature.
  • The differential diagnosis of malignant hamartoma was discussed.
  • [MeSH-major] Chondrosarcoma / pathology. Lung Neoplasms / pathology
  • [MeSH-minor] Female. Hamartoma / diagnosis. Hamartoma / pathology. Humans. Middle Aged

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  • (PMID = 17681099.001).
  • [ISSN] 1525-7304
  • [Journal-full-title] Clinical lung cancer
  • [ISO-abbreviation] Clin Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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21. Silvestris N, Piscitelli D, Crucitta E, Fiore M, De Lena M, Lorusso V: Unusual response to second-line single-agent gemcitabine in locally advanced primary leiomyosarcoma of the lung: a case report. J Chemother; 2003 Oct;15(5):507-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual response to second-line single-agent gemcitabine in locally advanced primary leiomyosarcoma of the lung: a case report.
  • Primary leiomyosarcomas (LMSs) of the lung are extremely rare malignancies that have been the subject of single or small series of case reports.
  • Today, the gold standard of treatment in patients with locally advanced and metastatic disease includes one of the many possible regimens containing an anthracycline and/or ifosfamide.
  • Few chemotherapy agents are active in the second-line setting.
  • In particular, gemcitabine is considered quite ineffective in the treatment of first- as well as second-line chemotherapy of soft tissue sarcoma and responses to this agent are seldom reported.
  • In this paper, we report a single patient with primary LMS of the lung previously treated with a combination of epirubicin and ifosfamide.
  • The patient responded to second-line chemotherapy with gemcitabine 1250 mg/m2 given as a 30-minute infusion on days 1, 8, and 15 of a 28-day cycle and showed an 8-month response duration and negligible toxicity.
  • Gemcitabine may represent an alternative to the best supportive care in patients affected with soft tissue sarcoma who fail first-line chemotherapy.
  • [MeSH-major] Antimetabolites, Antineoplastic / therapeutic use. Deoxycytidine / analogs & derivatives. Deoxycytidine / therapeutic use. Leiomyosarcoma / drug therapy. Lung Neoplasms / drug therapy
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Drug Resistance, Neoplasm. Epirubicin / administration & dosage. Epirubicin / pharmacology. Humans. Ifosfamide / administration & dosage. Ifosfamide / pharmacology. Male. Middle Aged

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  • (PMID = 14603882.001).
  • [ISSN] 1120-009X
  • [Journal-full-title] Journal of chemotherapy (Florence, Italy)
  • [ISO-abbreviation] J Chemother
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; 3Z8479ZZ5X / Epirubicin; B76N6SBZ8R / gemcitabine; UM20QQM95Y / Ifosfamide
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22. Brassens S, Chevalier JM, Leblainvaux M: [A strange case of phlebitis]. Ann Cardiol Angeiol (Paris); 2003 Dec;52(6):375-8

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Report of a rare case concerning an elderly man (81 years) suffering from a leiomyosarcoma of the leg already metastasized to the lungs, discovered in connection with a suspected thrombophlebitis.
  • This sarcoma developed from the smooth muscle of a leg vessel, probably a vein.
  • Leiomyosarcoma is a malignant mesenchymal tumor of specialized connective tissue, with a strong potential for local proliferation and metastatic spread.
  • The diagnosis suggested by imaging techniques (in particular MRI) is first and foremost immunohistochemical.
  • The treatment is surgical when possible, associated with radiotherapy and chemotherapy as appropriate.
  • The prognosis is especially poor when the diagnosis is made at the metastatic stage.
  • [MeSH-major] Leiomyosarcoma / diagnosis. Popliteal Vein / pathology. Thrombophlebitis / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Fatal Outcome. Humans. Knee / blood supply. Lung Neoplasms / secondary. Male

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  • (PMID = 14752921.001).
  • [ISSN] 0003-3928
  • [Journal-full-title] Annales de cardiologie et d'angéiologie
  • [ISO-abbreviation] Ann Cardiol Angeiol (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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23. Niamut SM, de Vries PA, van Putten JW, de Jong RS: [Eosinophilia caused by solid malignancy]. Ned Tijdschr Geneeskd; 2004 Sep 18;148(38):1883-6
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  • A 48-year-old woman with exanthema, pruritus and eosinophilia was found upon further examination to have a small-cell bronchus carcinoma; after chemotherapy and radiotherapy there was an almost complete response and the skin symptoms disappeared.
  • He was found to have a metastased leiomyosarcoma and died shortly afterwards.
  • It is important to recognise this phenomenon of paraneoplastic eosinophilia for the timely diagnosis and treatment of the underlying disease.
  • [MeSH-major] Carcinoma, Small Cell / complications. Eosinophilia / etiology. Leiomyosarcoma / complications. Lung Neoplasms / complications

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  • (PMID = 15497785.001).
  • [ISSN] 0028-2162
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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24. Miura S, Meirmanov S, Nakashima M, Hayashi T, Abe K, Tamaru N, Miyahara Y, Sekine I: Intimal sarcoma of the pulmonary artery: report of an autopsy case. Pathol Res Pract; 2005;201(6):469-74
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  • [Title] Intimal sarcoma of the pulmonary artery: report of an autopsy case.
  • Primary pulmonary artery sarcomas (PASs) are rare and lethal tumors.
  • They are easily misdiagnosed as chronic pulmonary embolism, mediastinal mass or tumor emboli, which delay a proper treatment.
  • Although the advanced technologies are now increasingly being used, their diagnosis is usually hard to establish preoperatively at the present time.
  • We report here a case of a 68-year-old female with PAS with lung metastases, who firstly presented with symptoms of common cold and anemia.
  • Although a PAS had been suspected, the final diagnosis of pulmonary intimal sarcoma was made only postoperatively by histological and immunohistochemical examination.
  • The patient died 8 months after the operation because of tumor growth progression, despite adjuvant chemotherapy and radiation therapy.
  • Although pulmonary intimal sarcomas are usually of poorly differentiated mesenchymal malignancy, most reported cases are immunohistochemically positive for vimentin, alpha-smooth muscle actin (SMA), and/or desmin, therefore resembling leiomyosarcomas.
  • However, the diagnosis of leiomyosarcoma should not be made on the basis of immunostains in the absence of typical morphologic features, and PAS, like the present case, should be more appropriately classified as intimal sarcoma according to the new WHO Classification of Tumours of Soft Tissue and Bone published in 2002.
  • [MeSH-major] Lung Neoplasms / secondary. Pulmonary Artery / pathology. Sarcoma / secondary. Tunica Intima / pathology. Vascular Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / metabolism. Endarterectomy. Fatal Outcome. Female. Humans. Neoplasm Recurrence, Local. Radiography, Thoracic. Tomography, X-Ray Computed

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  • (PMID = 16136754.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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25. Emori M, Naka N, Hamada K, Tomita Y, Takami H, Araki N: Soft-tissue sarcomas in the inguinal region may present as deep vein thrombosis. Ann Vasc Surg; 2010 Oct;24(7):951.e7-951.e11
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  • [Title] Soft-tissue sarcomas in the inguinal region may present as deep vein thrombosis.
  • Swelling, pain, and discoloration in the affected extremities are classic symptoms of deep vein thrombosis (DVT), although these symptoms are often unreliable for diagnosis, and wide differential diagnoses exist.
  • Soft-tissue sarcomas arising in the inguinal region may encompass or be adjacent to femoral vessels and result in venous obstruction, mimicking symptoms of DVT.
  • We present two cases of soft-tissue sarcomas in the inguinal region that were initially misdiagnosed as spontaneous DVT and administered unnecessary long-term anticoagulation therapy.
  • In patients diagnosed with unprovoked DVT, especially young patients aged <45 years, we recommend a careful physical examination and ultrasonography in the inguinal region to prevent overlooking possible underlying malignancy, as delays in diagnosis may affect prognosis.
  • [MeSH-major] Diagnostic Errors. Leiomyosarcoma / diagnosis. Lower Extremity / blood supply. Sarcoma, Synovial / diagnosis. Soft Tissue Neoplasms / diagnosis. Vascular Diseases / etiology. Venous Thrombosis / diagnosis
  • [MeSH-minor] Adult. Anticoagulants / administration & dosage. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Biopsy. Blood Vessel Prosthesis Implantation. Chemotherapy, Adjuvant. Constriction, Pathologic. Edema / etiology. Fatal Outcome. Female. Humans. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Magnetic Resonance Imaging. Male. Neoadjuvant Therapy. Time Factors. Treatment Outcome. Ultrasonography, Doppler, Duplex. Unnecessary Procedures. Veins / pathology

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  • [Copyright] Copyright © 2010 Annals of Vascular Surgery Inc. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20471794.001).
  • [ISSN] 1615-5947
  • [Journal-full-title] Annals of vascular surgery
  • [ISO-abbreviation] Ann Vasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticoagulants
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26. Böhm P, Kunz W, Horny HP, Einsele H: Adult Gaucher disease in association with primary malignant bone tumors. Cancer; 2001 Feb 1;91(3):457-62
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  • Thus, the recommendations for an adequate therapy are often based on limited professional experience.
  • To their knowledge, the authors report the first case of a leiomyosarcoma of the bone in a patient with GD and report another patient with GD and an anaplastic large cell non-Hodgkin lymphoma with localized osseous manifestation.
  • Epidemiologic data, clinical data, and treatment results from published reports of 18 patients who had GD and various malignancies and the authors' 2 patients were compared and evaluated.
  • RESULTS: Radiographic examination showed a destructive osteolytic lesion in a case of a leiomyosarcoma of the bone and in a case of anaplastic, large-cell, non-Hodgkin lymphoma.
  • In both patients, chemotherapy was performed.
  • Whereas the patient who had the leiomyosarcoma showed poor recovery of the bone marrow that necessitated withdrawal of aggressive chemotherapy, the patient who had non-Hodgkin lymphoma and enzyme therapy tolerated the chemotherapy well.
  • In spite of local control after preoperative radiotherapy and hemipelvectomy, the first patient developed lung metastases and finally died.
  • The second patient was continuously free of disease at a follow-up examination 32 months after chemotherapy and radiotherapy.
  • CONCLUSIONS: Because there is a relatively high incidence of malignant disorders of the bone, the study suggested that malignant disorders have to be included in the differential diagnosis of painful lytic lesions in patients who have GD.
  • Evaluation of the expense and value of enzyme therapy to patients who have GD should be undertaken with regard to the incidence of malignant disorders and patient survival.
  • [MeSH-minor] Adult. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / therapeutic use. Cyclophosphamide / therapeutic use. Doxorubicin / therapeutic use. Etoposide / therapeutic use. Female. Humans. Ifosfamide / therapeutic use. Male. Prednisone / therapeutic use. Vincristine / therapeutic use

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  • Hazardous Substances Data Bank. ETOPOSIDE .
  • Hazardous Substances Data Bank. IFOSFAMIDE .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • Hazardous Substances Data Bank. PREDNISONE .
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  • [Copyright] Copyright 2001 American Cancer Society.
  • (PMID = 11169926.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 11056-06-7 / Bleomycin; 5J49Q6B70F / Vincristine; 6PLQ3CP4P3 / Etoposide; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; UM20QQM95Y / Ifosfamide; VB0R961HZT / Prednisone; VACOP-B protocol
  • [Number-of-references] 22
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