[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 18 of about 18
1. Hara T, Tsurumi H, Kasahara S, Ogawa K, Takada J, Imai K, Takai K, Kitagawa J, Kiyama S, Imai N, Oyama M, Takami T, Moriwaki H: Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation. Intern Med; 2010;49(20):2253-7
Hazardous Substances Data Bank. VINCRISTINE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Long-term survival of a patient with splenic angiosarcoma after resection, high-dose chemotherapy, and autologous peripheral blood stem cell transplantation.
  • Histological examination was typical for angiosarcoma.
  • Adjuvant chemotherapy was given, and high-dose chemotherapy with autologous peripheral blood stem cell transplantation was performed.
  • Thrombocytopenia developed again in 2008.
  • CT scan showed a hepatic tumor.
  • A fine-needle biopsy of the liver revealed the first relapse.
  • Despite hepatic lobectomy, radiofrequency ablations and administration of recombinant interleukin-2, she died from respiratory failure in 2009.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Hemangiosarcoma / therapy. Peripheral Blood Stem Cell Transplantation. Splenectomy. Splenic Neoplasms / therapy
  • [MeSH-minor] Catheter Ablation. Chemotherapy, Adjuvant. Combined Modality Therapy. Cyclophosphamide / administration & dosage. Doxorubicin / administration & dosage. Fatal Outcome. Female. Hepatectomy. Humans. Interleukin-3 / therapeutic use. Middle Aged. Prednisone / administration & dosage. Recombinant Proteins / therapeutic use. Thrombocytopenia / etiology. Vincristine / administration & dosage

  • Genetic Alliance. consumer health - Transplantation.
  • Hazardous Substances Data Bank. DOXORUBICIN .
  • Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .
  • Hazardous Substances Data Bank. PREDNISONE .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20962445.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Interleukin-3; 0 / Recombinant Proteins; 5J49Q6B70F / Vincristine; 80168379AG / Doxorubicin; 8N3DW7272P / Cyclophosphamide; VB0R961HZT / Prednisone; CHOP protocol
  •  go-up   go-down


2. Sorenmo K, Samluk M, Clifford C, Baez J, Barrett JS, Poppenga R, Overley B, Skorupski K, Oberthaler K, Van Winkle T, Seiler G, Shofer F: Clinical and pharmacokinetic characteristics of intracavitary administration of pegylated liposomal encapsulated doxorubicin in dogs with splenic hemangiosarcoma. J Vet Intern Med; 2007 Nov-Dec;21(6):1347-54
Hazardous Substances Data Bank. DOXORUBICIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical and pharmacokinetic characteristics of intracavitary administration of pegylated liposomal encapsulated doxorubicin in dogs with splenic hemangiosarcoma.
  • BACKGROUND: Canine splenic hemangiosarcoma (HSA) is a fatal malignancy, and most affected dogs die within a few months of diagnosis.
  • All 12 dogs died because of HSA-related causes and had hepatic metastases and hemoabdomen.
  • Results of the postmortem examination and pharmacokinetic analysis confirmed that IP delivery of doxorubicin resulted in an effective drug concentration with a clearance comparable with that after i.v. delivery.

  • MedlinePlus Health Information. consumer health - Cancer Chemotherapy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18196746.001).
  • [ISSN] 0891-6640
  • [Journal-full-title] Journal of veterinary internal medicine
  • [ISO-abbreviation] J. Vet. Intern. Med.
  • [Language] ENG
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / liposomal doxorubicin; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin
  •  go-up   go-down


3. O'Grady JG: Treatment options for other hepatic malignancies. Liver Transpl; 2000 Nov;6(6 Suppl 2):S23-9
MedlinePlus Health Information. consumer health - Liver Transplantation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment options for other hepatic malignancies.
  • 1. Resection rates for cholangiocarcinoma (unrelated to primary sclerosing cholangitis) have increased to 54% to 79%, and the subsequent 5-year survival rates are 24% to 31%.
  • 2. Multimodality approaches involving various combinations of chemotherapy, irradiation, and surgery increasingly are being used to treat cholangiocarcinoma.
  • 3. The role of liver transplantation in the management of cholangiocarcinoma is limited by the perception that it is inappropriate to use scarce organs when 5-year survival rates are 25%.
  • 4. Liver transplantation is an important intervention in patients with tumors that remain unresectable after chemotherapy.
  • The role of liver transplantation in patients with extrahepatic disease that responds to chemotherapy is controversial.
  • Careful timing of surgery is required to avoid secondary drug resistance.
  • 5. Liver transplantation has been successfully applied to a range of rare hepatic malignancies, but small numbers preclude strong recommendations on the appropriateness of this practice.
  • [MeSH-major] Liver Neoplasms / therapy. Liver Transplantation
  • [MeSH-minor] Bile Duct Neoplasms / therapy. Bile Ducts, Intrahepatic. Cholangiocarcinoma / diagnosis. Cholangiocarcinoma / surgery. Cholangiocarcinoma / therapy. Combined Modality Therapy. Cystadenocarcinoma / therapy. Genetic Therapy. Hemangioendothelioma / therapy. Hemangiosarcoma / therapy. Hepatoblastoma / therapy. Humans. Neuroendocrine Tumors / therapy. Palliative Care

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11084081.001).
  • [ISSN] 1527-6465
  • [Journal-full-title] Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
  • [ISO-abbreviation] Liver Transpl.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] UNITED STATES
  • [Number-of-references] 26
  •  go-up   go-down


Advertisement
4. Matthaei H, Boelke E, Eisenberger CF, Alldinger I, Krieg A, Schmelzle M, Poremba C, Schellhammer F, Knoefel WT, Budach W, Peiper M: Interdisciplinary treatment of primary hepatic angiosarcoma: emergency tumor embolization followed by elective surgery. Eur J Med Res; 2007 Dec 14;12(12):591-4
NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Interdisciplinary treatment of primary hepatic angiosarcoma: emergency tumor embolization followed by elective surgery.
  • Among primary hepatic malignancies, sarcomas represent a minority of 2 %.
  • Of those, primary hepatic angiosarcoma is the most common one.
  • Without treatment most of them die after rapid tumor progression with multifocal dissemination.
  • - We herein report the successful interdisciplinary treatment of an 81 year-old woman with a perforated primary hepatic angiosarcoma of the left hepatic lobe.
  • - So far, no standard therapy has established for patients with primary hepatic angiosarcoma.
  • Surgery seems to be the treatment of choice.
  • The value of adjuvant chemotherapy is not yet clarified.
  • - The outcome of most patients with primary hepatic angiosarcoma remains poor and there is a need for clinical studies.
  • [MeSH-major] Embolization, Therapeutic. Hemangiosarcoma / therapy. Liver Neoplasms / therapy
  • [MeSH-minor] Aged, 80 and over. Combined Modality Therapy. Emergency Treatment. Female. Humans. Tomography, X-Ray Computed. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18024270.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


5. Dimashkieh HH, Mo JQ, Wyatt-Ashmead J, Collins MH: Pediatric hepatic angiosarcoma: case report and review of the literature. Pediatr Dev Pathol; 2004 Sep-Oct;7(5):527-32
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pediatric hepatic angiosarcoma: case report and review of the literature.
  • Pediatric hepatic angiosarcoma (PHAS) is a rare tumor, which usually presents as a rapid enlargement of the liver.
  • To date, surgery, chemotherapy, and radiotherapy have not improved the poor prognosis of PHAS with only three survivors reported.
  • The histology of PHAS is distinct from adult angiosarcoma, because PHAS displays hypercellular whorls of sarcomatous cells, or "kaposiform" spindle cells, in addition to the general features of angiosarcoma.
  • We report a case of PHAS that was treated with vascular ablation, chemotherapy, and liver transplantation.
  • [MeSH-major] Hemangiosarcoma / secondary. Hemangiosarcoma / therapy. Liver Neoplasms / pathology. Liver Neoplasms / therapy
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Child, Preschool. Diagnosis, Differential. Embolization, Therapeutic. Female. Humans. Liver Transplantation. Lung Neoplasms / secondary. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Pediatr Dev Pathol. 2004 Sep-Oct;7(5):A5-7 [15568213.001]
  • (PMID = 15547777.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


6. Kim HR, Rha SY, Cheon SH, Roh JK, Park YN, Yoo NC: Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma. Ann Oncol; 2009 Apr;20(4):780-7
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical features and treatment outcomes of advanced stage primary hepatic angiosarcoma.
  • BACKGROUND: Primary hepatic angiosarcoma is a very rare malignancy with a poor prognosis.
  • Nonetheless, treatment protocols have not been established and also there are very few reports on the clinical features and treatment outcomes.
  • PATIENTS AND METHODS: Among 11,939 patients diagnosed with primary hepatic tumors from January 1985 to December 2007 at two centers, five patients were diagnosed with primary hepatic angiosarcoma.
  • We analyzed patients' demographics, tumor characteristics, treatment modality, and outcomes using imaging, serology, and pathology.
  • Two of four patients who received chemotherapy died <3 months after diagnosis, but the other two patients survived >6 months.
  • CONCLUSIONS: A combination of chemotherapy resulted in an improved outcome for two of four patients, suggesting the potential usefulness of palliative chemotherapy to improve survival.
  • This case study may aid in planning chemotherapy for patients with advanced hepatic angiosarcoma.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19179547.001).
  • [ISSN] 1569-8041
  • [Journal-full-title] Annals of oncology : official journal of the European Society for Medical Oncology
  • [ISO-abbreviation] Ann. Oncol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


7. Nord KM, Kandel J, Lefkowitch JH, Lobritto SJ, Morel KD, North PE, Garzon MC: Multiple cutaneous infantile hemangiomas associated with hepatic angiosarcoma: case report and review of the literature. Pediatrics; 2006 Sep;118(3):e907-13
MedlinePlus Health Information. consumer health - Skin Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple cutaneous infantile hemangiomas associated with hepatic angiosarcoma: case report and review of the literature.
  • Multiple cutaneous hemangiomas can be associated with internal hemangiomas, with the liver being the most common site.
  • Here we report a case of a premature female neonate who presented with cardiac failure at birth and had typical-appearing infantile hemangiomas on the skin in association with vascular lesions in the liver.
  • Her clinical presentation was felt to be consistent with cutaneous and hepatic infantile hemangiomas.
  • After failure to respond to systemic steroids and chemotherapy, she underwent liver transplantation.
  • Histopathologic evaluation of the liver revealed a diagnosis of type 2 infantile hepatic hemangioendothelioma (regarded as synonymous with angiosarcoma) rather than benign infantile hemangioma of the liver.
  • Subsequent skin biopsies confirmed that her multiple cutaneous lesions were infantile hemangiomas and not metastatic angiosarcoma.
  • We report this case and a review of the literature on pediatric angiosarcoma of the liver associated with cutaneous infantile hemangiomas.
  • [MeSH-major] Hemangioma / pathology. Hemangiosarcoma / pathology. Liver Neoplasms / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Female. Heart Defects, Congenital. Humans. Infant, Newborn. Liver Transplantation

  • MedlinePlus Health Information. consumer health - Birthmarks.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Pediatrics. 2007 Jun;119(6):1271
  • (PMID = 16880251.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 27
  •  go-up   go-down


8. Rosenthal AK, Klausmeier M, Cronin ME, McLaughlin JK: Hepatic angiosarcoma occurring after cyclophosphamide therapy: case report and review of the literature. Am J Clin Oncol; 2000 Dec;23(6):581-3
Hazardous Substances Data Bank. CYCLOPHOSPHAMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hepatic angiosarcoma occurring after cyclophosphamide therapy: case report and review of the literature.
  • A 54-year-old man with polyarteritis nodosa developed acute onset of right upper quadrant abdominal pain associated with a large liver mass.
  • Transvenous liver biopsy revealed hepatic angiosarcoma, a rare liver tumor classically associated with environmental toxins.
  • A review of the literature revealed two other cases of hepatic angiosarcoma in patients after long-term cyclophosphamide treatment.
  • We propose that cyclophosphamide be added to the list of exposures potentially associated with hepatic angiosarcoma.
  • [MeSH-major] Cyclophosphamide / adverse effects. Hemangiosarcoma / chemically induced. Immunosuppressive Agents / adverse effects. Liver Neoplasms / chemically induced
  • [MeSH-minor] Humans. Male. Middle Aged. Polyarteritis Nodosa / drug therapy

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11202801.001).
  • [ISSN] 0277-3732
  • [Journal-full-title] American journal of clinical oncology
  • [ISO-abbreviation] Am. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunosuppressive Agents; 8N3DW7272P / Cyclophosphamide
  • [Number-of-references] 14
  •  go-up   go-down


9. Alliot C, Tribout B, Barrios M, Gontier MF: Angiosarcoma variant of Kasabach-Merritt syndrome. Eur J Gastroenterol Hepatol; 2001 Jun;13(6):731-4
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma variant of Kasabach-Merritt syndrome.
  • Here we report the case of a 70-year-old man in whom DIC revealed a locally advanced hepatic tumour.
  • Histopathological examination by autopsy allowed the diagnosis of hepatic angiosarcoma.
  • The physiopathogenic mechanisms and treatment options are discussed.
  • [MeSH-major] Disseminated Intravascular Coagulation / etiology. Hemangiosarcoma / pathology. Liver Neoplasms / pathology
  • [MeSH-minor] Aged. Autopsy. Biopsy, Needle. Diagnosis, Differential. Drug Therapy, Combination. Fatal Outcome. Humans. Immunohistochemistry. Male. Syndrome. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11434603.001).
  • [ISSN] 0954-691X
  • [Journal-full-title] European journal of gastroenterology & hepatology
  • [ISO-abbreviation] Eur J Gastroenterol Hepatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


10. Emre S, McKenna GJ: Liver tumors in children. Pediatr Transplant; 2004 Dec;8(6):632-8
MedlinePlus Health Information. consumer health - Liver Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Liver tumors in children.
  • Primary hepatic neoplasms in children are relatively infrequent, accounting for between 0.5 and 2.0% of all pediatric neoplasms.
  • They are clinically relevant tumors however as two thirds of them are malignant.
  • The therapy of these tumors has evolved over time and it currently involves a combination of surgery, adjuvant and neoadjuvant chemotherapy and possible transplantation.
  • [MeSH-major] Liver Neoplasms / diagnosis. Liver Neoplasms / therapy
  • [MeSH-minor] Carcinoma, Hepatocellular / diagnosis. Carcinoma, Hepatocellular / therapy. Child. Hamartoma / diagnosis. Hamartoma / therapy. Hemangioendothelioma / diagnosis. Hemangioendothelioma / therapy. Hemangiosarcoma / diagnosis. Hepatoblastoma / pathology. Hepatoblastoma / therapy. Humans. Neoplasm Staging. Sarcoma / diagnosis. Sarcoma / therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15598339.001).
  • [ISSN] 1397-3142
  • [Journal-full-title] Pediatric transplantation
  • [ISO-abbreviation] Pediatr Transplant
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 66
  •  go-up   go-down


11. Budd GT: Management of angiosarcoma. Curr Oncol Rep; 2002 Nov;4(6):515-9
The Lens. Cited by Patents in .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Management of angiosarcoma.
  • Angiosarcoma is an uncommon tumor that presents in several scenarios.
  • Although angiosarcoma can occur in any organ, it typically presents in the following settings:.
  • 1) in the face or scalp among elderly patients, 2) with chronic lymphedema, 3) after radiotherapy, or 4) as a hepatic primary.
  • In all of these situations, angiosarcoma is associated with multifocality and an insidious growth pattern, making local control difficult.
  • Doxorubicin-ifosfamide chemotherapy produces a modest response rate, and paclitaxel appears to be useful for scalp and facial angiosarcomas.
  • However, improvement in systemic therapy is clearly needed.
  • One logical strategy is to investigate antiangiogenic therapies in this endothelial tumor.
  • Improved therapy for this tumor will come only with greater understanding of its biology.
  • [MeSH-major] Head and Neck Neoplasms / therapy. Hemangiosarcoma / therapy
  • [MeSH-minor] Age Factors. Angiogenesis Inhibitors / therapeutic use. Female. Humans. Interferons / therapeutic use. Liver Neoplasms / etiology. Liver Neoplasms / therapy. Lymphedema / pathology. Male. Neoplasm Recurrence, Local. Prognosis. Sex Factors. Skin Neoplasms / therapy. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Head and Neck Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Cancer Res. 2000 Sep 15;60(18):5117-24 [11016638.001]
  • [Cites] Int J Cancer. 1996 Nov 27;68(5):596-9 [8938140.001]
  • [Cites] N Engl J Med. 1992 May 28;326(22):1456-63 [1489383.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Mar 15;52(4):1032-40 [11958899.001]
  • [Cites] Oncol Rep. 1999 Sep-Oct;6(5):959-64 [10425286.001]
  • [Cites] Am J Pathol. 1998 Nov;153(5):1425-33 [9811333.001]
  • [Cites] J Am Acad Dermatol. 1999 Jun;40(6 Pt 1):925-9 [10365923.001]
  • [Cites] Eur J Dermatol. 2000 Jun;10(4):300-2 [10846259.001]
  • [Cites] Clin Cancer Res. 2002 Jan;8(1):267-74 [11801568.001]
  • [Cites] Oncology. 1995 Jan-Feb;52(1):51-4 [7528371.001]
  • [Cites] Cancer Res. 1999 Jan 1;59(1):99-106 [9892193.001]
  • [Cites] J Surg Oncol. 2000 Mar;73(3):182-8 [10738275.001]
  • [Cites] J Clin Oncol. 1993 Jul;11(7):1276-85 [8315425.001]
  • [Cites] Am J Dermatopathol. 1986 Oct;8(5):371-8 [3777374.001]
  • [Cites] Cancer. 1989 Jul 15;64(2):484-90 [2736494.001]
  • [Cites] Cancer. 1998 Jan 1;82(1):8-34 [9428476.001]
  • [Cites] J Cancer Res Clin Oncol. 2000 Apr;126(4):219-25 [10782895.001]
  • [Cites] J Am Acad Dermatol. 1999 Jul;41(1):127-9 [10411427.001]
  • [Cites] J Clin Oncol. 1987 Jun;5(6):840-50 [3585441.001]
  • [Cites] Cancer. 1948 May;1(1):64-81 [18867440.001]
  • [Cites] Cancer. 1995 Jul 15;76(2):319-27 [8625109.001]
  • [Cites] J Cancer Res Clin Oncol. 1999 Oct;125(10):577-81 [10473871.001]
  • [Cites] J Exp Ther Oncol. 1996 May;1(3):186-90 [9414403.001]
  • [Cites] FASEB J. 2001 May;15(7):1318-20 [11344126.001]
  • [Cites] Clin Cancer Res. 2000 Jan;6(1):166-71 [10656446.001]
  • [Cites] Biochem Pharmacol. 2001 Feb 1;61(3):253-70 [11172729.001]
  • [Cites] Br J Dermatol. 1999 Jun;140(6):1187-8 [10354104.001]
  • [Cites] J Clin Oncol. 1987 Jun;5(6):851-61 [3295129.001]
  • [Cites] Br J Surg. 2000 Nov;87(11):1500-5 [11091236.001]
  • [Cites] N Engl J Med. 2000 Dec 7;343 (23 ):1673-80 [11106716.001]
  • [Cites] Cancer Invest. 1998;16(7):442-6 [9774950.001]
  • [Cites] Clin Cancer Res. 1999 Nov;5(11):3516-22 [10589766.001]
  • [Cites] Cancer. 1995 Dec 1;76(11):2248-52 [8635028.001]
  • [Cites] Head Neck. 2000 Mar;22(2):183-9 [10679908.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1999 Apr 1;44(1):113-9 [10219803.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Apr 1;52(5):1231-7 [11955733.001]
  • [Cites] Arch Dermatol. 1999 Sep;135(9):1035-7 [10490107.001]
  • [Cites] J Clin Oncol. 2000 May;18(10):2081-6 [10811673.001]
  • [Cites] Cancer. 1987 Mar 1;59(5):1046-57 [3815265.001]
  • [Cites] Ann Surg Oncol. 1998 Jan-Feb;5(1):48-53 [9524708.001]
  • [Cites] Cancer Res. 1999 May 15;59(10 ):2376-83 [10344747.001]
  • [Cites] N Engl J Med. 2000 Dec 7;343 (23 ):1666-72 [11106715.001]
  • [Cites] J Interferon Res. 1992 Dec;12 (6):455-8 [1289413.001]
  • [Cites] Lab Invest. 1995 Dec;73(6):859-63 [8558848.001]
  • [Cites] J Clin Oncol. 1995 Jul;13(7):1537-45 [7602342.001]
  • [Cites] J Clin Oncol. 1993 Jul;11(7):1269-75 [8315424.001]
  • [Cites] Cancer. 1999 Nov 15;86(10):2034-7 [10570428.001]
  • [Cites] CA Cancer J Clin. 1981 Sep-Oct;31(5):284-99 [6793218.001]
  • (PMID = 12354365.001).
  • [ISSN] 1523-3790
  • [Journal-full-title] Current oncology reports
  • [ISO-abbreviation] Curr Oncol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 9008-11-1 / Interferons
  • [Number-of-references] 49
  •  go-up   go-down


12. Al Dhaybi R, Agoumi M, Powell J, Dubois J, Kokta V: Lymphangiosarcoma complicating extensive congenital mixed vascular malformations. Lymphat Res Biol; 2010 Sep;8(3):175-9
Genetic Alliance. consumer health - Vascular Malformations.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Pediatric hepatic angiosarcoma is a very rare malignant vascular tumor.
  • A few cases have shown pediatric hepatic angiosarcoma occurring on a background of preexisting vascular lesions.
  • Compressive body suit therapy led to regression of the limbs' cutaneous vascular malformations.
  • Aggressive treatment with prednisone, vincristine, and hepatosplenic embolizations resulted in initial improvement of the hepatosplenic lesions for few months, followed by an increase of the lesions with failure of response to treatment despite adding alpha-interferon-2b to treatment.
  • The autopsy's pathological examination revealed a hepatic-based angiosarcoma with plurimetastatic dissemination to the spleen, lungs, peritoneum, pleura, mesenteric linings as well as the serosa of the stomach and small intestine.
  • We hypothesize that these multiple extensive mixed vascular malformations were associated with chronic lymphedema which probably predisposed to the development of the angiosarcoma in our patient.
  • [MeSH-minor] Autopsy. Fatal Outcome. Female. Humans. Infant. Infant, Newborn. Skin Diseases, Vascular / complications. Skin Diseases, Vascular / congenital. Skin Diseases, Vascular / drug therapy

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20863270.001).
  • [ISSN] 1557-8585
  • [Journal-full-title] Lymphatic research and biology
  • [ISO-abbreviation] Lymphat Res Biol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


13. Fraiman G, Ganti AK, Potti A, Mehdi S: Angiosarcoma of the small intestine: a possible role for thalidomide? Med Oncol; 2003;20(4):397-402
Hazardous Substances Data Bank. THALIDOMIDE .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Angiosarcoma of the small intestine: a possible role for thalidomide?
  • Surgical exploration for possible angiodysplasia, malignancy, and/or mesenteric ischemia revealed an incarcerated hernia, and the histopathological examination of the surgical specimen revealed high-grade angiosarcoma.
  • At that time he was found to have hepatic metastases.
  • [MeSH-major] Angiogenesis Inhibitors / therapeutic use. Hemangiosarcoma / drug therapy. Intestinal Neoplasms / drug therapy. Thalidomide / therapeutic use
  • [MeSH-minor] Aged. Aged, 80 and over. Anemia, Iron-Deficiency / complications. Humans. Liver Neoplasms / secondary. Male

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Pathol. 1978 Aug;92(2):349-76 [567014.001]
  • [Cites] Cancer. 1987 Aug 15;60(4):777-9 [3297296.001]
  • [Cites] Cancer. 1979 Dec;44(6):2049-58 [389408.001]
  • [Cites] Cancer. 1991 May 1;67(9):2275-9 [2013033.001]
  • [Cites] Cancer. 1981 Oct 15;48(8):1907-21 [7197190.001]
  • [Cites] Histopathology. 1979 Mar;3(2):131-52 [457040.001]
  • [Cites] Cancer. 1988 Jul 1;62(1):210-6 [3383117.001]
  • [Cites] Cancer. 1988 Dec 1;62(11):2436-44 [3052791.001]
  • [Cites] Medicine (Baltimore). 1979 Jan;58(1):48-64 [368508.001]
  • [Cites] Am J Gastroenterol. 1983 Apr;78(4):218-21 [6404159.001]
  • [Cites] Am J Gastroenterol. 1994 May;89(5):797-800 [8172159.001]
  • [Cites] N Engl J Med. 1999 Nov 18;341(21):1565-71 [10564685.001]
  • [Cites] Am J Clin Pathol. 1988 Apr;89(4):463-71 [2451419.001]
  • [Cites] Int J STD AIDS. 1998 Dec;9(12):751-5 [9874123.001]
  • [Cites] Cancer. 1979 Dec;44(6):2044-8 [389407.001]
  • [Cites] Br J Cancer. 2000 Feb;82(4):812-7 [10732751.001]
  • [Cites] Surg Gynecol Obstet. 1949 Apr;88(4):281-323 [18113323.001]
  • [Cites] Cancer. 1983 Mar 1;51(5):878-81 [6821853.001]
  • [Cites] J Clin Oncol. 2000 Feb;18(4):708-15 [10673511.001]
  • [Cites] Surg Gynecol Obstet. 1976 Nov;143(5):717-9 [982248.001]
  • [Cites] Hematol Oncol Clin North Am. 2001 Oct;15(5):835-51, viii [11765376.001]
  • [Cites] South Med J. 1981 Oct;74(10):1201-3 [7292058.001]
  • [Cites] Dis Colon Rectum. 1990 Apr;33(4):330-3 [2182313.001]
  • (PMID = 14716038.001).
  • [ISSN] 1357-0560
  • [Journal-full-title] Medical oncology (Northwood, London, England)
  • [ISO-abbreviation] Med. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Angiogenesis Inhibitors; 4Z8R6ORS6L / Thalidomide
  •  go-up   go-down


14. Deutsch M, Wollman MR: Radiotherapy for metastases to the mandible in children. J Oral Maxillofac Surg; 2002 Mar;60(3):269-71
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Six children had a neuroblastoma, 1 had angiosarcoma of the liver, 1 had adenocarcinoma of the rectum, and 1 had peripheral primitive neuroectodermal tumor (Ewing's sarcoma) of the spine.
  • All children had received chemotherapy.
  • RESULTS: All children died of disseminated disease at 5 to 59 months from their initial diagnosis, 5 to 29 months from the detection of metastases to bone, and only 6 days to 17 months (median, 2 months) from the first treatment of metastases to the mandible.
  • CONCLUSIONS: The outlook for children with metastases that involve the mandible is very poor, and we recommend short intensive courses of radiotherapy consisting of 1 to 3 treatments to total doses of 400 to 1,200 cGy for palliation of pain.
  • [MeSH-minor] Adenocarcinoma / radiotherapy. Adenocarcinoma / secondary. Adolescent. Child. Child, Preschool. Female. Hemangiosarcoma / radiotherapy. Hemangiosarcoma / secondary. Humans. Infant. Liver Neoplasms / pathology. Male. Neuroblastoma / radiotherapy. Neuroblastoma / secondary. Pain, Intractable / radiotherapy. Radiotherapy Dosage. Rectal Neoplasms / pathology. Retrospective Studies. Sarcoma, Ewing / radiotherapy. Sarcoma, Ewing / secondary. Spinal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Palliative Care.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2002 American Association of Oral and Maxillofacial Surgeons
  • (PMID = 11887137.001).
  • [ISSN] 0278-2391
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


15. Poggio JL, Nagorney DM, Nascimento AG, Rowland C, Kay P, Young RM, Donohue JH: Surgical treatment of adult primary hepatic sarcoma. Br J Surg; 2000 Nov;87(11):1500-5
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical treatment of adult primary hepatic sarcoma.
  • BACKGROUND: Primary sarcomas of the liver are extremely rare in adults.
  • Optimal therapeutic approaches remain unclear.
  • METHODS: Twenty consecutive adult patients who had surgical treatment for primary hepatic sarcomas were reviewed.
  • Other than one patient with primary hepatic angiosarcoma who had a history of thorium dioxide colloid (Thorotrast) exposure 23 years before diagnosis, no predisposing causes were apparent.
  • Nineteen patients had hepatic resection and one patient had an orthotopic liver transplant.
  • No patient received neoadjuvant chemotherapy or radiotherapy but radiotherapy was delivered intraoperatively in one patient.
  • RESULTS: Leiomyosarcoma was the most common histological type of sarcoma diagnosed (five of 20 patients), followed by malignant solitary fibrous tumour (four) and epithelioid haemangioendothelioma (three).
  • Thirteen patients developed a recurrence.
  • Distant metastases (ten patients) and intrahepatic recurrence (six) were the predominant sites of initial treatment failure.
  • Six patients received salvage chemotherapy.
  • CONCLUSION: Surgical resection is the only effective therapy for primary hepatic sarcomas at present.
  • Better adjuvant therapy is necessary, especially for high-grade malignancies, owing to the high failure rate with operation alone.
  • [MeSH-major] Liver Neoplasms / surgery. Sarcoma / surgery
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antineoplastic Agents / therapeutic use. Disease-Free Survival. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Preoperative Care / methods. Retrospective Studies

  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • MedlinePlus Health Information. consumer health - Soft Tissue Sarcoma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 11091236.001).
  • [ISSN] 0007-1323
  • [Journal-full-title] The British journal of surgery
  • [ISO-abbreviation] Br J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  •  go-up   go-down


16. Srivastava A, Nielsen PG, Dal Cin P, Rosenberg AE: Monophasic synovial sarcoma of the liver. Arch Pathol Lab Med; 2005 Aug;129(8):1047-9
COS Scholar Universe. author profiles.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Monophasic synovial sarcoma of the liver.
  • We report a hepatic monophasic synovial sarcoma in a 60-year-old woman who presented with right upper quadrant pain subsequent to an intrahepatic bleed from a highly vascular tumor mass.
  • Imaging studies showed a dominant tumor mass in the right hepatic lobe with multiple satellite nodules.
  • A detailed physical examination and radiologic workup failed to reveal a primary tumor elsewhere.
  • A right partial hepatectomy was performed with a preoperative differential diagnosis of angiosarcoma versus hepatocellular carcinoma.
  • The patient was started on an aggressive 4-drug chemotherapy regimen, but died 3 months thereafter from widespread metastatic disease.
  • The presence of multiple lesions in the liver certainly suggests the possibility of metastatic disease.
  • It would, however, be very unusual for a synovial sarcoma to present as an occult primary, and the negative radiologic workup 1 month after the partial hepatectomy also argues against this possibility.
  • The clinical presentation, radiographic findings, and subsequent course in this patient was therefore most consistent with a primary monophasic synovial sarcoma of the liver.
  • [MeSH-major] Liver Neoplasms / diagnosis. Sarcoma, Synovial / diagnosis
  • [MeSH-minor] Carcinoma, Hepatocellular / diagnosis. Chemotherapy, Adjuvant. Chromosomes, Human, Pair 18. Chromosomes, Human, X. Diagnosis, Differential. Fatal Outcome. Female. Genetic Markers. Hemangiosarcoma / diagnosis. Hepatectomy. Humans. Middle Aged. Translocation, Genetic

  • Genetic Alliance. consumer health - Synovial sarcoma.
  • MedlinePlus Health Information. consumer health - Liver Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16048399.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Genetic Markers
  •  go-up   go-down


17. Hohenhaus AE: Transfusion issues in the cancer patient. Clin Tech Small Anim Pract; 2003 May;18(2):135-8
MedlinePlus Health Information. consumer health - Blood Transfusion and Donation.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Blood transfusions are a lifesaving but transient therapy used to correct deficiencies of blood cells and coagulation factors that occur in cancer patients.
  • The blood component most commonly recommended for the treatment of anemia is packed red blood cells.
  • Coagulation disorders are common with hemangiosarcoma and diffuse hepatic tumors.
  • Fresh frozen plasma is used as a source for replacement coagulation factors for the treatment of disseminated intravascular coagulation or other cancer-associated coagulopathies.
  • Although thrombocytopenia and neutropenia can be the result of bone-marrow failure from tumor infiltration, chemotherapy, or radiation therapy, these platelets and neutrophils are rarely transfused to veterinary cancer patients.
  • [MeSH-major] Anemia / veterinary. Blood Coagulation Disorders / veterinary. Blood Transfusion / veterinary. Cat Diseases / therapy. Dog Diseases / therapy. Neoplasms / veterinary

  • MedlinePlus Health Information. consumer health - Anemia.
  • MedlinePlus Health Information. consumer health - Bleeding Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 12831078.001).
  • [ISSN] 1096-2867
  • [Journal-full-title] Clinical techniques in small animal practice
  • [ISO-abbreviation] Clin Tech Small Anim Pract
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
  •  go-up   go-down


18. Costero-Barrios CB, Oros-Ovalle C: [Primary renal angiosarcoma]. Gac Med Mex; 2004 Jul-Aug;140(4):463-6
MedlinePlus Health Information. consumer health - Kidney Cancer.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Primary renal angiosarcoma].
  • [Transliterated title] Angiosarcoma renal primario.
  • The twenty-fourth case of primary renal angiosarcoma is described, according to the available international literature, this present in a 71-year-old male, a mechanic by trade, without carcinogenic antecedents.
  • Hematuria, pain in flank, and left-side tumoral mass of approximately 20 cm in diameter located in kidney by computerized axial tomography (CT) constituted manifestations.
  • The patient was subjected to treatment with chemotherapy and radiotherapy (lineal accelerator), but 12 months after surgery he presented retroperitonal tumoral relapse and hepatic metastasis.
  • Diagnostic differentiation with benign vascular tumors is pointed out, as well as carcinomas and sarcomas that showed an outstanding angiomatous component, both primary and/or secondary.
  • Primary renal angiosarcoma exposes the multiplicity of localizations that it is capable of with a tumor of this type, as well as renal parenquimatous capacity to be the seat of a great variety of neoplasias.
  • [MeSH-major] Hemangiosarcoma / pathology. Kidney / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Aged. Humans. Male. Nephrectomy / methods. Tomography, X-Ray Computed. Treatment Outcome

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15456157.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
  •  go-up   go-down






Advertisement