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1. Gómez Esteban JC, Boyero S, Fernández C, Sagasta A, Pérez T, Velasco F, Allue I, Lezcano E, Zarranz JJ: [Baroreflex failure after chemodectoma resection]. Neurologia; 2004 Oct;19(8):452-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Baroreflex failure after chemodectoma resection].
  • [Transliterated title] Fallo barorreflejo tras intervención de un quemodectoma.
  • Baroreflex failure after chemodectoma resection We present a case of baroreflex failure secondary to a unilateral injury of the glossopharyngeal nerve.
  • The patient was operated for a left-sided chemodectoma in the carotid body.
  • The diagnosis was baroreflex failure secondary to unilateral injury of the glossopharyngeal nerve.
  • The case reported herein illustrates the fact that the presence of a bilateral injury is not essential for the occurrence of this disorder.
  • [MeSH-major] Baroreflex. Glossopharyngeal Nerve Injuries. Neurosurgical Procedures / adverse effects. Paraganglioma, Extra-Adrenal / surgery
  • [MeSH-minor] Aged. Angiography. Antihypertensive Agents / therapeutic use. Autonomic Nervous System Diseases / etiology. Blood Pressure / drug effects. Clonidine / pharmacology. Female. Humans. Hypertension / drug therapy

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  • (PMID = 15470587.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antihypertensive Agents; MN3L5RMN02 / Clonidine
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2. Pacheco-Ojeda L: Malignant carotid body tumors: report of three cases. Ann Otol Rhinol Laryngol; 2001 Jan;110(1):36-40

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The first was in a 40-year-old man who presented with pulmonary metastases 6 years after resection of a CBT.
  • He was treated with chemotherapy and interferon, but died with disseminated disease 2 years later.
  • This lesion was completely resected, and a shunt and reconstruction with a saphenous vein graft were performed.
  • Pathology revealed a malignant chemodectoma with invasion to 2 of the 5 lymph nodes removed.
  • Radiotherapy (50 Gy) was given after the operation.
  • She is well and free of disease 68 months after the resection.
  • On computed tomography, the tumor extended to the infratemporal fossa with no bone involvement.
  • The lesion was embolized with a 40% reduction in vascularity.
  • At surgical exploration, the tumor involved the sternocleidomastoid muscle and the lymph nodes at levels II and III, and the internal carotid artery could not be dissected free at the skull base, so only a partial resection was performed.
  • Current multidisciplinary treatments have been unsuccessful in controlling disseminated disease.
  • [MeSH-major] Carotid Body Tumor. Paraganglioma, Extra-Adrenal

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  • (PMID = 11201806.001).
  • [ISSN] 0003-4894
  • [Journal-full-title] The Annals of otology, rhinology, and laryngology
  • [ISO-abbreviation] Ann. Otol. Rhinol. Laryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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3. Horenstein MG, Hitchcock TA, Tucker JA: Dual CD117 expression in gastrointestinal stromal tumor (GIST) and paraganglioma of Carney triad: a case report. Int J Surg Pathol; 2005 Jan;13(1):87-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Dual CD117 expression in gastrointestinal stromal tumor (GIST) and paraganglioma of Carney triad: a case report.
  • Carney triad is a rare syndrome, with only 20 complete cases reported.
  • We report a 36-year-old white woman with complete Carney triad, including metastatic gastric stromal tumor (GIST), pulmonary chondroma, and nonfunctioning extra-adrenal paraganglioma.
  • Immunohistochemistry was positive for CD34 and CD117 (c-kit) in the GIST, and positive for chromogranin and CD117 in the paraganglioma.
  • To our knowledge, this is the 21st complete Carney triad case reported and the first report of dual expression CD117 in both GIST and paraganglioma, a finding with intriguing pathogenetic implications related to the organization of the autonomic nervous system.
  • [MeSH-major] Chondroma / pathology. Gastrointestinal Stromal Tumors / pathology. Leiomyosarcoma / secondary. Lung Neoplasms / pathology. Paraganglioma, Extra-Adrenal / pathology. Proto-Oncogene Proteins c-kit / analysis
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Antineoplastic Agents / therapeutic use. Biomarkers, Tumor / analysis. Chromogranins / analysis. Drug Therapy. Female. Humans. Palliative Care. Syndrome

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  • (PMID = 15735861.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Antineoplastic Agents; 0 / Biomarkers, Tumor; 0 / Chromogranins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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4. Widimský J Jr, Zelinka T, Petrák O, Strauch B, Safarík L, Kasalický M, Vranková A, Holaj R: [Diagnostic and therapeutic procedures in pheochromocytoma: current trends]. Vnitr Lek; 2007 Apr;53(4):428-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Diagnostic and therapeutic procedures in pheochromocytoma: current trends].
  • It is therefore important to correctly diagnose this disease.
  • 24-hour monitoring of blood pressure (BP) can already contribute to the diagnosis of pheochromacytoma based on the frequent occurrence of BP variability and the absence of a night-time fall in BP.
  • 5 gene mutations have so far been identified that may be responsible for the familial form of pheochromacytoma: mutation of the von Hippel-Lindau (VHL) gene, leading to the onset of VHL syndrome, mutation of the RET-proto-oncogene in multiple endocrine adenomatosis type 2, mutation of the type 1 gene for neurofibromatosis, which is associated with von Recklinghausen's disease and finally mutation of the genes encoding the B and D subunits of succinated hydrogenase (SDHB, SDHD), which are associated with familial paragangliomas and pheochromacytoma.
  • The diagnosis of extraadrenal or multiple forms can use not only CT/MR but also imaging using the radiopharmaceutical 123I-Metaiodobenzylguanidine (MIBG) or 18F-fluorodopamine PET (only available in the USA).
  • Pharmacological treatment using alpha or beta receptor blockers with subsequent laparoscopic excision of the tumor is usually successful in benign forms of pheochromocytoma.
  • Unfortunately, there are still no convincingly effective therapeutic procedures available for malign forms.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Pheochromocytoma / diagnosis
  • [MeSH-minor] Humans. Hypertension / etiology. Multiple Endocrine Neoplasia Type 2a / diagnosis. Neurofibromatosis 1 / diagnosis. Paraganglioma / diagnosis. von Hippel-Lindau Disease / diagnosis. von Hippel-Lindau Disease / etiology

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  • (PMID = 17578179.001).
  • [ISSN] 0042-773X
  • [Journal-full-title] Vnitr̆ní lékar̆ství
  • [ISO-abbreviation] Vnitr Lek
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Czech Republic
  • [Number-of-references] 25
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6. Sawhney SA, Chapman AD, Carney JA, Gomersall LN, Dempsey OJ: Incomplete Carney triad--a review of two cases. QJM; 2009 Sep;102(9):649-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • 'Carney's triad' characteristically includes multifocal pulmonary chondroma, gastric stromal sarcoma and extra-adrenal paraganglioma.
  • [MeSH-major] Chondroma / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. Liver Neoplasms / diagnosis. Lung Neoplasms / diagnosis. Paraganglioma, Extra-Adrenal / diagnosis
  • [MeSH-minor] Adult. Anti-Bacterial Agents / therapeutic use. Antineoplastic Agents / therapeutic use. Benzamides. Bronchial Diseases / drug therapy. Bronchial Diseases / etiology. Female. Humans. Imatinib Mesylate. Neoplasms, Multiple Primary / diagnosis. Piperazines / therapeutic use. Pyrimidines / therapeutic use. Tomography, X-Ray Computed

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  • (PMID = 19561114.001).
  • [ISSN] 1460-2393
  • [Journal-full-title] QJM : monthly journal of the Association of Physicians
  • [ISO-abbreviation] QJM
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
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7. Kavakli K, Ozturk M, Ongoru O, Gürkök S, Genc O: Primary pulmonary paraganglioma with Hodgkin's lymphoma. Thorac Cardiovasc Surg; 2009 Sep;57(6):375-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary pulmonary paraganglioma with Hodgkin's lymphoma.
  • Extra-adrenal paragangliomas are uncommon tumors arising from neuroectodermal-derived paraganglionic tissue.
  • There are very few case reports on primary pulmonary paraganglioma in the literature.
  • We present the case of a 21-year-old man who was treated with chemotherapy for Hodgkin's lymphoma.
  • Only a partial response was noted so he underwent additional chemotherapy and involved field radiotherapy.
  • Subsequent bronchoscopic biopsy showed paraganglioma and the patient underwent a left lower lobectomy.
  • [MeSH-major] Hodgkin Disease / diagnosis. Lung Neoplasms / diagnosis. Paraganglioma, Extra-Adrenal / diagnosis
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols. Biopsy. Bronchoscopy. Chemotherapy, Adjuvant. Humans. Lymph Node Excision. Male. Pneumonectomy. Positron-Emission Tomography. Radiotherapy, Adjuvant. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • [Copyright] Georg Thieme Verlag KG Stuttgart New York.
  • (PMID = 19707986.001).
  • [ISSN] 1439-1902
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 7
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