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Items 1 to 13 of about 13
1. Braun RP, French LE, Feldmann R, Chavaz P, Saurat JH: Cutaneous pseudolymphoma, lymphomatoid contact dermatitis type, as an unusual cause of symmetrical upper eyelid nodules. Br J Dermatol; 2000 Aug;143(2):411-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cutaneous pseudolymphoma, lymphomatoid contact dermatitis type, as an unusual cause of symmetrical upper eyelid nodules.
  • We describe a 74-year-old woman who rapidly developed bilateral voluminous nodules on the upper eyelids, following 4 months' treatment for chalazion.
  • Histological and immunohistochemical findings were suggestive of cutaneous pseudolymphoma (CPL), and extensive screening for malignant lymphoma (ML) remained negative.
  • Cutaneous pseudolymphomas are inflammatory diseases that can simulate ML either clinically, histopathologically, or both.
  • They are a rare cause of nodules of the upper eyelids, usually characterized by a benign evolution, that can be secondary to ultraviolet sensitivity, adverse reactions to systemic medications and contact sensitization, among others.
  • In our case, epicutaneous patch tests were strongly positive for a series of allergens contained in the ophthalmological preparations used; therefore, they were suggestive that the patient had CPL, lymphomatoid contact dermatitis type.
  • In addition, the patient had been treated previously with several drugs, known to cause CPL and immune dysregulation.
  • Complete regression of the lesions required treatment with systemic steroids and chlorambucil.
  • [MeSH-major] Dermatitis, Allergic Contact / diagnosis. Eyelid Diseases / diagnosis. Pseudolymphoma / diagnosis
  • [MeSH-minor] Aged. Chalazion / drug therapy. Diagnosis, Differential. Female. Humans. Lymphoma / diagnosis

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  • [CommentIn] Br J Dermatol. 2006 Sep;155(3):633-4 [16911299.001]
  • (PMID = 10951155.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] ENGLAND
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2. Stavrianeas NG, Katoulis AC, Bozi E, Toumbis-Ioannou E, Kanelleas AI, Makris M, Kalogeromitros D, Panayiotides I: Cutaneous pseudolymphoma following administration of lornoxicam. Acta Derm Venereol; 2007;87(5):453-5
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  • [Title] Cutaneous pseudolymphoma following administration of lornoxicam.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / adverse effects. Piroxicam / analogs & derivatives. Pseudolymphoma / chemically induced. Skin Diseases / chemically induced
  • [MeSH-minor] Adult. Back Pain / drug therapy. Humans. Male

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  • (PMID = 17721665.001).
  • [ISSN] 0001-5555
  • [Journal-full-title] Acta dermato-venereologica
  • [ISO-abbreviation] Acta Derm. Venereol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal; 13T4O6VMAM / Piroxicam; ER09126G7A / lornoxicam
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3. Magro CM, Crowson AN, Kovatich AJ, Burns F: Drug-induced reversible lymphoid dyscrasia: a clonal lymphomatoid dermatitis of memory and activated T cells. Hum Pathol; 2003 Feb;34(2):119-29
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  • [Title] Drug-induced reversible lymphoid dyscrasia: a clonal lymphomatoid dermatitis of memory and activated T cells.
  • Certain systemic conditions predispose patients to excessive lymphocyte responses to immune-perturbing drugs, which may progress to malignant lymphoma.
  • Many pathologists and clinicians believe that differentiation of pseudolymphoma from cutaneous T cell lymphoma (CTCL) can be reliably made through phenotypic and molecular analysis.
  • We encountered 15 cases of atypical cutaneous T-cell lymphoid hyperplasia in the setting of drug therapy.
  • The lymphoid infiltrates showed reproducible CD7 and/or CD62 K deletion in concert with T cell clonality and variable CD30 positivity-findings similar to those of CTCL-but the rashes resolved or improved substantially after drug modulation.
  • We propose the term "drug-induced reversible lymphoid dyscrasia" to describe this entity.
  • [MeSH-major] Dermatitis / etiology. Pseudolymphoma / chemically induced. Pseudolymphoma / pathology. T-Lymphocytes / pathology

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  • [Copyright] Copyright 2003, Elsevier Science (USA). All rights reserved.
  • (PMID = 12612879.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD
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4. McComb ME, Telang GH, Vonderheid EC: Secondary syphilis presenting as pseudolymphoma of the skin. J Am Acad Dermatol; 2003 Aug;49(2 Suppl Case Reports):S174-6
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  • [Title] Secondary syphilis presenting as pseudolymphoma of the skin.
  • The papulonodular variant has only been described 11 times in the literature.
  • We describe a case of papulonodular secondary syphilis presenting as an atypical lymphoid hyperplasia suggestive of cutaneous lymphoma.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / pathology. Syphilis, Cutaneous / pathology
  • [MeSH-minor] Adult. Anti-Bacterial Agents. Biopsy, Needle. Diagnosis, Differential. Drug Therapy, Combination / administration & dosage. Follow-Up Studies. Humans. Immunohistochemistry. Male. Risk Assessment. Severity of Illness Index. Treatment Outcome

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  • (PMID = 12894114.001).
  • [ISSN] 0190-9622
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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5. Grogg KL, Jung S, Erickson LA, McClure RF, Dogan A: Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior. Mod Pathol; 2008 Jun;21(6):708-15
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  • [Title] Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior.
  • Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma, a provisional entity in the 2005 WHO-EORTC classification for cutaneous lymphomas, is not well characterized.
  • The majority resolved without relapse, one without treatment, four with excision, and four with radiation therapy.
  • One patient developed local recurrence.
  • The patient with multiple lesions had disease progression despite chemotherapy and stem cell transplant.
  • The differential diagnosis includes reactive lymphoid hyperplasia, mycosis fungoides and cutaneous B-cell lymphomas.
  • In patients with isolated cutaneous lesions, the indolent behavior of this rare T-cell neoplasm should be recognized to avoid unnecessary treatment.
  • [MeSH-major] CD4-Positive T-Lymphocytes / pathology. Lymphoma, T-Cell, Cutaneous / pathology. Skin Neoplasms / pathology

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  • (PMID = 18311111.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Historical Article; Journal Article
  • [Publication-country] United States
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6. Addeo R, Montella L, Baldi A, Cennamo G, Guarrasi R, Faiola V, Caraglia M, Del Prete S: Atypical cutaneous lymphoid hyperplasia induced by chemotherapy in a patient with advanced colon carcinoma. Clin Colorectal Cancer; 2007 Nov;6(10):728-30
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  • [Title] Atypical cutaneous lymphoid hyperplasia induced by chemotherapy in a patient with advanced colon carcinoma.
  • Some conditions are predisposed to excessive lymphocyte responses, which can progress to a benign condition, ie, atypical cutaneous lymphoid hyperplasia (ACLH), or a malignant lymphoma.
  • Clinical diagnosis of drug-associated pseudolymphoma can be based on a temporal association between drug ingestion and lesion onset followed by resolution without recurrence after discontinuation of drug administration.
  • Herein, we report the case of a 66-year-old man with advanced colon carcinoma with ACLH developed while receiving chemotherapy regimen with oxaliplatin/5-fluorouracil/leucovorin.
  • The authors postulate that chemotherapy can promote an aberrant immune response to an antigen that can be the drug itself or other self-antigens.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / adverse effects. Colonic Neoplasms / drug therapy. Drug Eruptions / etiology. Lymphatic Diseases / chemically induced

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  • (PMID = 18039427.001).
  • [ISSN] 1533-0028
  • [Journal-full-title] Clinical colorectal cancer
  • [ISO-abbreviation] Clin Colorectal Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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7. Kim KJ, Lee MW, Choi JH, Sung KJ, Moon KC, Koh JK: CD30-positive T-cell-rich pseudolymphoma induced by gold acupuncture. Br J Dermatol; 2002 May;146(5):882-4
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  • [Title] CD30-positive T-cell-rich pseudolymphoma induced by gold acupuncture.
  • Cases of pseudolymphoma induced by intradermal gold injection or gold piercing have previously been described.
  • Most of these cases showed the histopathological finding of B-lymphocyte predominant lymphocytoma cutis.
  • We describe a patient with gold acupuncture-induced T-cell-rich pseudolymphoma.
  • [MeSH-major] Acupuncture Therapy / adverse effects. Drug Eruptions / etiology. Gold / adverse effects. Pseudolymphoma / chemically induced. T-Lymphocyte Subsets / pathology

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  • (PMID = 12000389.001).
  • [ISSN] 0007-0963
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD30; 7440-57-5 / Gold
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8. Malphettes M, Oksenhendler E, Galicier L, Fieschi C: [Granulomatous disease in common variable immunodeficiency]. Rev Med Interne; 2008 Jan;29(1):28-32
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  • Repeated bacterial infections and/or autoimmune manifestations and/or benign lymphoproliferation (including follicular hyperplasia and/or granulomatous disease) are the hallmark of the disease.
  • This review aims at describing recent advances in the understanding and treatment of granulomatous disease in CVID.
  • Granulomas may be found in several organs in a single patient, and the main features are pulmonary, lymphoid, cutaneous, hepatic or splenic.
  • Treatment consists in immunoglobulins substitution, immunosuppressive agents (corticosteroids, cyclophosphamide) and anti-TNFalpha antibodies.
  • These treatments are difficult to manage in such immunocompromised patients.

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  • (PMID = 18054123.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Immunoglobulins; 0 / Immunologic Factors; 0 / Immunosuppressive Agents
  • [Number-of-references] 21
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9. Wiesli P, Joos L, Galeazzi RL, Dummer R: Cutaneous pseudolymphoma associated with bromocriptine therapy. Clin Endocrinol (Oxf); 2000 Nov;53(5):656-7
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  • [Title] Cutaneous pseudolymphoma associated with bromocriptine therapy.
  • [MeSH-major] Bromocriptine / adverse effects. Drug Eruptions / etiology. Hormone Antagonists / adverse effects. Pseudolymphoma / chemically induced. Skin Diseases / chemically induced

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  • (PMID = 11106930.001).
  • [ISSN] 0300-0664
  • [Journal-full-title] Clinical endocrinology
  • [ISO-abbreviation] Clin. Endocrinol. (Oxf)
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] ENGLAND
  • [Chemical-registry-number] 0 / Hormone Antagonists; 3A64E3G5ZO / Bromocriptine
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10. Prais D, Straussberg R, Amir J, Nussinovitch M, Harel L: Treatment of anticonvulsant hypersensitivity syndrome with intravenous immunoglobulins and corticosteroids. J Child Neurol; 2006 May;21(5):380-4
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  • [Title] Treatment of anticonvulsant hypersensitivity syndrome with intravenous immunoglobulins and corticosteroids.
  • Anticonvulsant hypersensitivity syndrome is a specific severe idiosyncratic reaction to the aromatic antiepileptic drugs.
  • The most frequent presenting symptoms are fever and rash, lymphadenopathy owing to lymphoid hyperplasia, hepatitis, and interstitial nephritis.
  • Early detection is crucial owing to the high mortality rate.
  • Although withdrawal of the offending drug is critical, the optimal treatment approach remains controversial.
  • Previous studies report a severe course and prolonged hospital stay for cutaneous drug-related reactions, including referral to a burn center, skin d├ębridement, and allograft skin coverage.
  • The aim of the present report is to describe four adolescents with antiepileptic drug hypersensitivity syndrome who were treated with intravenous immunoglobulin and systemic corticosteroids.
  • Findings indicate that this regimen might be a promising treatment option in this patient population.
  • Larger, controlled trials are needed to reach a definitive conclusion.
  • [MeSH-major] Anticonvulsants / adverse effects. Drug Hypersensitivity / drug therapy. Glucocorticoids / therapeutic use. Immunoglobulins, Intravenous / therapeutic use. Immunologic Factors / therapeutic use. Methylprednisolone / therapeutic use
  • [MeSH-minor] Adolescent. Drug Therapy, Combination. Female. Humans. Infusions, Intravenous. Syndrome

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  • (PMID = 16901442.001).
  • [ISSN] 0883-0738
  • [Journal-full-title] Journal of child neurology
  • [ISO-abbreviation] J. Child Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Glucocorticoids; 0 / Immunoglobulins, Intravenous; 0 / Immunologic Factors; X4W7ZR7023 / Methylprednisolone
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11. Jain M, Agarwal K, Langer S, Aggarwal M: Cytomorphology of a case of primary cutaneous B-cell lymphoma. Indian J Pathol Microbiol; 2007 Oct;50(4):877-80
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  • [Title] Cytomorphology of a case of primary cutaneous B-cell lymphoma.
  • Primary cutaneous lymphoma designates a heterogenous group of disorders arising from skin T and B cells with no evidence of extra cutaneous disease at the time of diagnosis and six months thereafter.
  • We report the cytomorphological features of a case of primary cutaneous lymphoma, B cell type in a 60 year old female presenting with multiple large bosselated red coloured swellings all over the scalp.
  • On cytology a diagnosis of B-cell cutaneous lymphoid hyperplasia (B-CLH) was given, however cutaneous lymphoma could not be ruled out.
  • On biopsy and immuno-histochemistry a diagnosis of primary cutaneous lymphoma B cell type was made.
  • Patient was started on specific chemotherapy of lymphoma to which she responded completely.
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Biopsy. Female. Humans. Immunohistochemistry. Middle Aged. Scalp / pathology

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  • (PMID = 18306596.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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12. Breza TS Jr, Zheng P, Porcu P, Magro CM: Cutaneous marginal zone B-cell lymphoma in the setting of fluoxetine therapy: a hypothesis regarding pathogenesis based on in vitro suppression of T-cell-proliferative response. J Cutan Pathol; 2006 Jul;33(7):522-8
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  • [Title] Cutaneous marginal zone B-cell lymphoma in the setting of fluoxetine therapy: a hypothesis regarding pathogenesis based on in vitro suppression of T-cell-proliferative response.
  • INTRODUCTION: Drugs may be an important cause of atypical lymphocytic infiltration.
  • We report a patient who developed lymphocytoma cutis temporally associated with initiation of fluoxetine therapy that later went on to develop cutaneous marginal zone B-cell lymphoma.
  • The response of peripheral blood lymphocytes to fluoxetine and other drugs was examined in an attempt to ascertain the potential role for drugs in the propagation of these infiltrates.
  • MATERIALS AND METHODS: Routine light microscopic analysis and phenotypic studies were performed on tissue obtained from a skin biopsy.
  • RESULTS: An initial biopsy was consistent with lymphocytoma cutis.
  • Other tested drugs did not have a similar suppressive effect.
  • [MeSH-minor] Anticonvulsants / pharmacology. Bupropion / pharmacology. Cells, Cultured. Dose-Response Relationship, Drug. Humans. In Situ Hybridization. Lymphocyte Activation / drug effects. Male. Middle Aged. Pseudolymphoma / chemically induced. Pseudolymphoma / pathology. T-Lymphocytes / drug effects. T-Lymphocytes / pathology

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  • (PMID = 16872479.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Anticonvulsants; 0 / Antidepressive Agents, Second-Generation; 01K63SUP8D / Fluoxetine; 01ZG3TPX31 / Bupropion
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13. Wang E, Stoecker M: Primary cutaneous giant cell plasmacytoma in an organ transplant recipient: a rare presentation of a posttransplant lymphoproliferative disorder. Am J Dermatopathol; 2010 Jul;32(5):479-85
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  • [Title] Primary cutaneous giant cell plasmacytoma in an organ transplant recipient: a rare presentation of a posttransplant lymphoproliferative disorder.
  • Posttransplant lymphoproliferative disorder (PTLD) is comprised of a spectrum of lymphoid diseases, ranging from early lesions, such as plasmacytic hyperplasia, to monomorphic neoplasms, including plasmacytoma-like lesions.
  • Although PTLD may involve a variety of organs, primary cutaneous PTLD is rare.
  • We report a unique case of Epstein-Barr virus (EBV)-positive primary cutaneous giant cell plasmacytoma developed 5 years after renal/pancreatic transplant in a 55-year-old male patient.
  • A review of the literature identified additional 49 cases of primary cutaneous B-cell PTLD, including 18 cases of plasmacytoma-like lesions.
  • Primary cutaneous B-cell PTLD usually presents years after transplantation, has male preponderance, tends to occur on extremities, is frequently EBV-associated, and predicts a favorable clinical outcome.
  • Unlike PTLD in general, in which EBV-positive cases usually occur earlier than EBV-negative ones, the longer presentation interval in the cutaneous PTLD seems to be uncorrelated to EBV status.
  • Compared with other subtypes of cutaneous B-cell PTLD, plasmacytoma-like lesions have an increased male preponderance and tendency to present on the extremities.
  • Although the majority of cases have been treated with reduction of immunosuppression, antiviral therapy and/or local radiotherapy, and a few with chemotherapy, the best therapeutic intervention for primary cutaneous B-cell PTLD remains to be further investigated with the analysis of more reported cases and large clinical trials.






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