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1. Ozturk B, Tacoy G, Coskun U, Yaman E, Sahin G, Buyukberber S, Yildiz R, Kaya AO, Topal S, Ozdemir M, Benekli M: Gemcitabine-induced acute coronary syndrome: a case report. Med Princ Pract; 2009;18(1):76-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: To report a case of metastatic leiomyosarcoma, in which a patient developed chest pain accompanied by acute left bundle-branch block (LBBB) after gemcitabine infusion.
  • She was treated with gemcitabine infusion, and 30 min later she experienced severe chest pain accompanied by acute LBBB confirmed by ECG.
  • Her chest pain resolved and LBBB disappeared.
  • CONCLUSION: This case showed that chemotherapeutic agents must be administered with intensive cardiac monitoring especially in patients with cardiac disease and well-known risk factors to prevent the development of cardiac complications, despite an agent not being known to be 'cardiotoxic'.
  • [MeSH-minor] Aspirin / therapeutic use. Coronary Vasospasm / chemically induced. Electrocardiography. Fatal Outcome. Female. Humans. Leiomyosarcoma. Lung Neoplasms / secondary. Middle Aged. Platelet Aggregation Inhibitors / therapeutic use. Risk Factors. Ticlopidine / analogs & derivatives. Ticlopidine / therapeutic use

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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 19060498.001).
  • [ISSN] 1423-0151
  • [Journal-full-title] Medical principles and practice : international journal of the Kuwait University, Health Science Centre
  • [ISO-abbreviation] Med Princ Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Platelet Aggregation Inhibitors; 0W860991D6 / Deoxycytidine; A74586SNO7 / clopidogrel; B76N6SBZ8R / gemcitabine; OM90ZUW7M1 / Ticlopidine; R16CO5Y76E / Aspirin
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2. Ramsay LB, Stany MP, Edison JD, Bernstein SA, Schlegal KE, Hamilton CA: Gemcitabine-associated large vessel vasculitis presenting as fever of unknown origin. J Clin Rheumatol; 2010 Jun;16(4):181-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report a case of significant large vessel vasculitis presenting as fever of unknown origin in a patient treated adjuvantly with docetaxel and gemcitabine for uterine leiomyosarcoma.The patient presented after her first and second exposure to chemotherapy with fever of unknown origin and worsening subsequent chest and neck discomfort.
  • Awareness of this potential complication is essential as discontinuing the inciting drug and initiating corticosteroid treatment can be life-saving.

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  • (PMID = 20407388.001).
  • [ISSN] 1536-7355
  • [Journal-full-title] Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
  • [ISO-abbreviation] J Clin Rheumatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0W860991D6 / Deoxycytidine; 0Z5B2CJX4D / Fluorodeoxyglucose F18; B76N6SBZ8R / gemcitabine
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3. Kokubo Y, Uchida K, Kobayashi S, Yayama T, Sato R, Kakuyama M, Imamura Y, Baba H: Primary osteosarcoma of the thoracic spine: report of an unusual elderly patient with autopsy findings. Spinal Cord; 2005 Aug;43(8):508-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: The histopathological features of osteosarcoma vary widely, often leading to diagnostic difficulties particularly when there is little evidence of osteoid formation.
  • SETTING: Department of Orthopaedics and Rehabilitation Medicine, Fukui University Faculty of Medicine, Fukui, Japan.
  • The tissue also demonstrated positive immunohistochemical staining for vimentin and alpha-smooth muscle actin and a tentative diagnosis of leiomyosarcoma was made.
  • However, a metastatic nodule of the chest wall at autopsy showed focal osteoid formation, a finding not seen in the primary tumor.

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  • (PMID = 15753962.001).
  • [ISSN] 1362-4393
  • [Journal-full-title] Spinal cord
  • [ISO-abbreviation] Spinal Cord
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Vimentin
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4. Hadjiliadis D, Govert JA: Methemoglobinemia after infusion of ifosfamide chemotherapy: first report of a potentially serious adverse reaction related to ifosfamide. Chest; 2000 Oct;118(4):1208-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Acute formation of methemoglobin is a life-threatening condition caused by multiple medications.
  • In this article we report the first case of methemoglobinemia in a patient with metastatic uterine leiomyosarcoma, after infusion of ifosfamide chemotherapy.
  • [MeSH-major] Antineoplastic Agents, Alkylating / adverse effects. Ifosfamide / adverse effects. Leiomyosarcoma / drug therapy. Methemoglobinemia / chemically induced. Uterine Neoplasms / drug therapy

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  • (PMID = 11035699.001).
  • [ISSN] 0012-3692
  • [Journal-full-title] Chest
  • [ISO-abbreviation] Chest
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Alkylating; 0 / Biomarkers; 9008-37-1 / Methemoglobin; UM20QQM95Y / Ifosfamide
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5. Garland MR, Lawler LP, Whitaker BR, Walker ID, Corl FM, Fishman EK: Modern CT applications in veterinary medicine. Radiographics; 2002 Jan-Feb;22(1):55-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Modern CT applications in veterinary medicine.
  • CT and associated three-dimensional reconstruction have a role in diagnosis of a range of illnesses in a variety of animals.
  • In a sea turtle with failure to thrive, CT showed a nodal mass in the chest, granulomas in the lungs, and a ball in the stomach.
  • CT of a sea dragon with balance and movement problems showed absence of the swim bladder.
  • CT of a puffin with failure to thrive showed a mass in the chest, which was found to be a hematoma.
  • CT of a domestic cat with listlessness showed a mass with focal calcification, which proved to be a leiomyosarcoma.
  • CT of a sea otter showed pectus excavatum, which is caused by the animal smashing oysters against its chest.
  • [MeSH-minor] Animals. Anura. Carps. Cats. Image Processing, Computer-Assisted. Otters. Sloths. Turtles

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  • [Copyright] Copyright RSNA, 2002
  • (PMID = 11796898.001).
  • [ISSN] 0271-5333
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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