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1. Reich O: [Is early first intercourse a risk factor for cervical cancer?]. Gynakol Geburtshilfliche Rundsch; 2005 Oct;45(4):251-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Is early first intercourse a risk factor for cervical cancer?].
  • Sexual behavior has long been known to be a risk factor for cervical carcinoma.
  • Certain sexual risk factors are related to an increased risk of chronic infection of the cervical transformation zone with high-risk human papilloma viruses (HPVs).
  • Numerous retrospective analyses consider early first intercourse a probable risk factor for later development of cervical carcinoma.
  • Since risk factors are associated, it is unclear whether early first intercourse is an independent risk factor for cervical neoplasia.
  • It is possible that the cervical transformation zone is particularly vulnerable to infection between menarche and the age of sixteen.
  • During this phase there are a large number of undifferentiated cells at the periphery of the metaplasia, practically at the surface of the cervix.
  • Other possible risk factors for cervical cancer include genetic predisposition, nutrition, smoking, Chlamydia or HSV-2 infections, drug abuse, oral contraception, immune suppression and early first pregnancy.
  • [MeSH-major] Coitus. Uterine Cervical Neoplasms / etiology
  • [MeSH-minor] Adolescent. Cell Transformation, Neoplastic / pathology. Cervix Uteri / pathology. Female. Humans. Papillomavirus Infections / complications. Papillomavirus Infections / etiology. Papillomavirus Infections / pathology. Pregnancy. Risk Factors. Uterine Cervical Dysplasia / etiology. Uterine Cervical Dysplasia / pathology


2. Frikha M, Toumi N, Ghorbel L, Ben Salah H, Khabir A, Karray H, Gargouri R, Boudawara T, Ghorbel A, Daoud J: [Pediatric nasopharyngeal carcinoma: Anatomoclinic aspects, therapeutic results and evolutive particularities]. Cancer Radiother; 2010 Jun;14(3):169-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pediatric nasopharyngeal carcinoma: Anatomoclinic aspects, therapeutic results and evolutive particularities].
  • [Transliterated title] Le cancer du cavum de l'enfant et l'adulte jeune : aspects anatomocliniques, thérapeutiques et particularités évolutives.
  • PURPOSE: We retrospectively analyzed anatomoclinic, therapeutic and evolutive particularities of 74 young patients (< or =20 years) with nasopharyngeal carcinoma treated between 1993 and 2005.
  • Radiotherapy was delivered to a total dose of 70 to 75 Gy to nasopharynx and involved cervical lymph nodes and 50 Gy to the remainder cervical areas.
  • Sixty-three percent of patients had undifferentiated tumors.
  • COMMENTS: Pediatric nasopharyngeal carcinoma is characterized by an early metastatic diffusion.
  • [MeSH-major] Carcinoma / epidemiology. Cobalt Radioisotopes / therapeutic use. Nasopharyngeal Neoplasms / epidemiology. Radioisotope Teletherapy
  • [MeSH-minor] Adolescent. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Bleomycin / administration & dosage. Chemotherapy, Adjuvant. Child. Cisplatin / administration & dosage. Combined Modality Therapy. Disease-Free Survival. Epirubicin / administration & dosage. Female. Fluorouracil / administration & dosage. Follow-Up Studies. Humans. Kaplan-Meier Estimate. Lymphatic Metastasis. Male. Neoadjuvant Therapy. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / radiotherapy. Neoplasms, Radiation-Induced / etiology. Neoplasms, Second Primary / chemically induced. Neoplasms, Second Primary / etiology. Radiotherapy, Conformal. Retrospective Studies. Treatment Outcome. Xerostomia / epidemiology. Xerostomia / etiology. Young Adult

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  • [Copyright] 2010. Published by Elsevier SAS.
  • (PMID = 20347607.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Cobalt Radioisotopes; 11056-06-7 / Bleomycin; 3Z8479ZZ5X / Epirubicin; Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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3. Zannoni GF, Vellone VG, Carbone A: Morphological effects of radiochemotherapy on cervical carcinoma: a morphological study of 50 cases of hysterectomy specimens after neoadjuvant treatment. Int J Gynecol Pathol; 2008 Apr;27(2):274-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphological effects of radiochemotherapy on cervical carcinoma: a morphological study of 50 cases of hysterectomy specimens after neoadjuvant treatment.
  • The introduction of radiochemotherapy for treatment of advanced cervical cancers represents a new chapter in surgical pathology.
  • The study group included 50 women with a histological diagnosis of advanced cervical carcinoma (43 squamous, 3 adenosquamous, 2 adenocarcinoma, 1 glassy cell, and 1 undifferentiated; International Federation of Gynecology and Obstetrics stage Ib-III) receiving a platinum-based chemotherapy concomitant with external beam radiotherapy before radical surgery.
  • In most cases, morphological criteria are sufficient to make a diagnosis, but sometimes, the use of immunohistochemistry (keratins and CD68) is a mandatory method to reveal the nature of the lesion.
  • [MeSH-major] Carcinoma / pathology. Carcinoma, Adenosquamous / pathology. Carcinoma, Squamous Cell / pathology. Hysterectomy. Neoadjuvant Therapy / methods. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Antigens, CD / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Biomarkers, Tumor / metabolism. Cervix Uteri / drug effects. Cervix Uteri / radiation effects. Cervix Uteri / surgery. Combined Modality Therapy. Female. Humans. Keratins / metabolism. Middle Aged

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  • (PMID = 18317212.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD68 antigen, human; 68238-35-7 / Keratins
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4. Paradkar PN, Roth JA: Nitric oxide transcriptionally down-regulates specific isoforms of divalent metal transporter (DMT1) via NF-kappaB. J Neurochem; 2006 Mar;96(6):1768-77
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  • Studies were performed to examine the affect of nitric oxide (NO) on expression of the divalent metal transporter (DMT1) in undifferentiated P19 embryonic carcinoma cells.
  • DMT1 has four known isoforms which differ in both the N- and C-terminals.
  • Results of these studies provide a general mechanism responsible for regulating DMT1 expression induced by stress-related signaling processes in vivo.
  • [MeSH-major] Brain / metabolism. Cation Transport Proteins / genetics. Down-Regulation / physiology. Iron-Binding Proteins / genetics. NF-kappa B / metabolism. Neurons / metabolism. Nitric Oxide / metabolism. Regulatory Elements, Transcriptional / physiology
  • [MeSH-minor] Animals. Animals, Newborn. Cells, Cultured. Humans. Mice. Nitric Oxide Donors / pharmacology. Nitroprusside / pharmacology. PC12 Cells. Promoter Regions, Genetic / drug effects. Promoter Regions, Genetic / genetics. Protein Binding / drug effects. Protein Binding / physiology. Protein Isoforms / drug effects. Protein Isoforms / genetics. Protein Isoforms / metabolism. RNA, Messenger / drug effects. RNA, Messenger / metabolism. Rats. Rats, Sprague-Dawley. Superior Cervical Ganglion / drug effects. Superior Cervical Ganglion / metabolism. Transcription Factor RelA / metabolism

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  • (PMID = 16539692.001).
  • [ISSN] 0022-3042
  • [Journal-full-title] Journal of neurochemistry
  • [ISO-abbreviation] J. Neurochem.
  • [Language] eng
  • [Grant] United States / NIEHS NIH HHS / ES / R01 ES1112
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cation Transport Proteins; 0 / Iron-Binding Proteins; 0 / NF-kappa B; 0 / Nitric Oxide Donors; 0 / Protein Isoforms; 0 / RNA, Messenger; 0 / Rela protein, mouse; 0 / Transcription Factor RelA; 0 / solute carrier family 11- (proton-coupled divalent metal ion transporters), member 2; 169D1260KM / Nitroprusside; 31C4KY9ESH / Nitric Oxide
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5. Takashima T, Nakata B, Hatama M, Nomura S, Komoto M, Ishikawa T, Hirakawa K: Gastric cancer with cervical lymph node metastasis as the first presentation: report of a case. Int Surg; 2008 Sep-Oct;93(5):295-9
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  • [Title] Gastric cancer with cervical lymph node metastasis as the first presentation: report of a case.
  • Aspiration cytology revealed lymph node metastasis of undifferentiated carcinoma.
  • A Borrmann type 3 tumor was detected in the body of the stomach on endoscopic examination.
  • Pathological examination revealed that the histological features of the gastric lesion were identical to those of the cervical lymph node lesion.
  • Irradiation to the left supraclavicular and cervical region and an oral tegafur anticancer agent (TS-1) were started.

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  • (PMID = 19943433.001).
  • [ISSN] 0020-8868
  • [Journal-full-title] International surgery
  • [ISO-abbreviation] Int Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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6. Iagaru A, Masamed R, Singer PA, Conti PS: Detection of occult medullary thyroid cancer recurrence with 2-deoxy-2-[F-18]fluoro-D-glucose-PET and PET/CT. Mol Imaging Biol; 2007 Mar-Apr;9(2):72-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: 2-deoxy-2-[F-18]fluoro-D-glucose (FDG)-positron emission tomography (PET) has an established role in restaging of various cancers, including papillary and undifferentiated thyroid carcinoma.
  • METHODS: This is a retrospective study (Apr 1, 1997-Mar 31, 2004) of 13 patients with histologic diagnosis of MTC, who had PET examinations.
  • The lesions were located in superior mediastinum (4), cervical lymph nodes (3), thyroid bed (2), lung (1) and liver (1).
  • [MeSH-major] Brain Stem Neoplasms / diagnosis. Fluorodeoxyglucose F18. Neoplasm Recurrence, Local / diagnosis. Positron-Emission Tomography / methods. Thyroid Neoplasms / diagnosis

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  • (PMID = 17186139.001).
  • [ISSN] 1536-1632
  • [Journal-full-title] Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
  • [ISO-abbreviation] Mol Imaging Biol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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