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1. Miyake Y, Kato T, Katayama K, Doi T, Oshima K, Handa R, Hoshi M, Makari Y, Oshima S, Iijima S, Kurokawa E, Kikkawa N: [A case of ascending colon carcinoma metastasized to an inguinal hernia sac]. Gan To Kagaku Ryoho; 2007 Nov;34(12):2016-8
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  • [Title] [A case of ascending colon carcinoma metastasized to an inguinal hernia sac].
  • We report a case of ascending colon cancer metastasized to an inguinal hernia sac.
  • A 60-year-old man, who was undergone a right hemicolectomy for an ascending colon cancer, was pointed out a palpable inguinal mass at one year and eight months after the operation.
  • Histological examination revealed that the tumor was metastasis of colon carcinoma.
  • As for the advanced colon cancer, we need to mention the possibility of metastatic saccular tumor.
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Humans. Male. Middle Aged. Neoplasm Metastasis / drug therapy. Neoplasm Metastasis / pathology. Tomography, X-Ray Computed

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  • (PMID = 18219884.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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2. Fujie Y, Ikeda M, Seshimo I, Ezumi K, Hata T, Shingai T, Yasui M, Takayama O, Fukunaga H, Ikenaga M, Takemasa I, Yamamoto H, Ohue M, Sekimoto M, Hirota S, Monden M: Complete response of highly advanced colon cancer with multiple lymph node metastases to irinotecan combined with UFT: report of a case. Surg Today; 2006;36(12):1133-8
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  • [Title] Complete response of highly advanced colon cancer with multiple lymph node metastases to irinotecan combined with UFT: report of a case.
  • Massive lymph node metastasis of the para-aortic region and supraclavicular lymph nodes, Virchow's lymph node metastasis due to colon cancer, is extremely rare.
  • We herein report a case of such systemic lymph node metastasis that was successfully treated with a combination of irinotecan (CPT-11) and UFT, a combination drug of tegafur and uracil.
  • The patient was a 57-year-old woman who had a tumor in the ascending colon, and massively swollen para-aortic and supraclavicular lymph node metastasis.
  • Combination chemotherapy of CPT-11 and UFT may be of potential value in the treatment of advanced colorectal carcinoma, and both histopathological and immunohistochemical confirmation of a complete remission may indicate prolonged disease-free survival.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Camptothecin / analogs & derivatives. Colonic Neoplasms / drug therapy. Enzyme Inhibitors / therapeutic use

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  • [Cites] Arch Surg. 2000 May;135(5):530-4; discussion 534-5 [10807276.001]
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  • (PMID = 17123148.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Enzyme Inhibitors; 0 / Prodrugs; 0H43101T0J / irinotecan; 1548R74NSZ / Tegafur; 56HH86ZVCT / Uracil; XT3Z54Z28A / Camptothecin; 1-UFT protocol
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3. Saito H, Watanuki A, Tabira Y, Ikeda N, Urakawa M, Sakano T: [Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report]. Gan To Kagaku Ryoho; 2009 Nov;36(11):1907-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Huge ascending colon carcinoma, treated successfully with S-1 plus CPT-11, followed by significant tumor reduction and curative resection--a case report].
  • Computed tomography (CT) and colonoscopy (CF)revealed a huge ascending colon tumor, invading the descending part of the duodenum.
  • Resected specimen revealed residual tumor in a small area of the submucosal to proper muscular layer of the contracted ascending colon, without pathological invasion to the duodenum.
  • [MeSH-minor] Aged. Antimetabolites, Antineoplastic / administration & dosage. Antineoplastic Agents, Phytogenic / administration & dosage. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Colonoscopy. Combined Modality Therapy. Drug Combinations. Female. Humans. Oxonic Acid / administration & dosage. Tegafur / administration & dosage. Tomography, X-Ray Computed

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  • (PMID = 19920399.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; 7673326042 / irinotecan; XT3Z54Z28A / Camptothecin
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4. Pramateftakis MG: Optimizing colonic cancer surgery: high ligation and complete mesocolic excision during right hemicolectomy. Tech Coloproctol; 2010 Nov;14 Suppl 1:S49-51
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  • We present our experience with tumors of the proximal colon, for which a radical right hemicolectomy has been performed.
  • The tumor was located in the cecum in 37% of patients, the ascending colon in 58% of the patients and the hepatic flexure in 5% of the patients.
  • One patient developed a metachronous rectal carcinoma 28 months after his surgery, for which he underwent an abdoperineal resection.
  • It is important to remember that colon cancer treatment today is multimodal and that the improvement in patients' survival in the last decades is surely linked with the improvement in chemotherapy and the advances in the agents used.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Colon / blood supply. Colon / surgery. Colonic Neoplasms / surgery. Female. Humans. Ligation. Male. Middle Aged. Survival Analysis

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  • [Cites] Acta Oncol. 2009;48(8):1152-6 [19863223.001]
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  • (PMID = 20697925.001).
  • [ISSN] 1128-045X
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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5. Zambito Y, Baggiani A, Carelli V, Serafini MF, Di Colo G: Matrices for site-specific controlled-delivery of 5-fluorouracil to descending colon. J Control Release; 2005 Feb 16;102(3):669-77
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Matrices for site-specific controlled-delivery of 5-fluorouracil to descending colon.
  • Colon-specific controlled-delivery 5-fluorouracil (5-FU) matrices for the treatment of colorectal carcinoma were prepared and evaluated.
  • There, drug release should be prevented until matrices reach descending colon where release should occur.
  • Drug release was measured by the rotating basket method.
  • The matrix containing 60% w/w drug, prepared by compression of powders, was appropriate to make the planned system, in virtue of its fairly high drug load and its nearly constant and reasonable release rate.
  • When transit of coated matrix through ileum (phosphate buffer (PB) pH 7.4), ascending colon (PB pH 6 containing rat cecal contents) and descending colon (PB pH 7.4) was simulated in vitro, the pH 4.7 of the CH-HCl gel layer and the pH 6 of the ascending colon prevented dissolution of the protective EUD film until descending colon was reached, then controlled release started.
  • [MeSH-major] Colon, Descending / drug effects. Drug Delivery Systems / methods. Fluorouracil / administration & dosage
  • [MeSH-minor] Animals. Delayed-Action Preparations / administration & dosage. Delayed-Action Preparations / pharmacokinetics. Rats. Rats, Wistar

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  • (PMID = 15681088.001).
  • [ISSN] 0168-3659
  • [Journal-full-title] Journal of controlled release : official journal of the Controlled Release Society
  • [ISO-abbreviation] J Control Release
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Delayed-Action Preparations; U3P01618RT / Fluorouracil
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6. Paulsen JE, Elgjo K: Effect of tumour size on the in vivo growth inhibition of human colon carcinoma cells (HT-29) by colon mitosis inhibitor. In Vivo; 2001 Sep-Oct;15(5):397-401
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of tumour size on the in vivo growth inhibition of human colon carcinoma cells (HT-29) by colon mitosis inhibitor.
  • We have previously shown that the colon mitosis inhibitor (CMI) suppresses the growth of transplanted HT-29 human colon carcinoma cells by approximately 40%.
  • After ranking the terminal tumours by ascending size in the control group and the CMI group the growth inhibition was calculated at each rank position.
  • Consequently, a retrospective analysis of the smallest and slowest growing tumours showed a profound growth inhibition (72-81%, p < 0.008), whereas a similar analysis of the large and fast growing tumours revealed no significant CMI effect.
  • [MeSH-major] Adenocarcinoma / pathology. Antineoplastic Agents / therapeutic use. Colonic Neoplasms / pathology. Growth Inhibitors / therapeutic use. Oligopeptides / therapeutic use
  • [MeSH-minor] Animals. Cell Division / drug effects. Clone Cells / drug effects. Clone Cells / transplantation. Disease Progression. Eflornithine / pharmacology. Eflornithine / therapeutic use. Humans. Mice. Mice, Inbred BALB C. Mice, Nude. Neoplasm Transplantation. Pyrrolidonecarboxylic Acid / analogs & derivatives. Tretinoin / pharmacology. Tretinoin / therapeutic use. Tumor Cells, Cultured / drug effects. Tumor Cells, Cultured / transplantation. Xenograft Model Antitumor Assays

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  • (PMID = 11695236.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Growth Inhibitors; 0 / Oligopeptides; 5688UTC01R / Tretinoin; 69275-10-1 / pyroglutamyl-histidyl-glycine; SZB83O1W42 / Pyrrolidonecarboxylic Acid; ZQN1G5V6SR / Eflornithine
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7. Catalano C, Gianesini C, Fabbian F: Erythropoietin is beneficial in mitomycin-induced hemolytic-uremic syndrome. Nephron; 2002 Jun;91(2):324-6
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  • Mitomycin C is a powerful antineoplastic agent.
  • We describe a patient who developed HUS after treatment with mitomycin C (total dose 144 mg/m2) due to a carcinoma of the ascending colon.
  • [MeSH-major] Antibiotics, Antineoplastic / adverse effects. Erythropoietin / therapeutic use. Hemolytic-Uremic Syndrome / chemically induced. Hemolytic-Uremic Syndrome / drug therapy. Mitomycin / adverse effects
  • [MeSH-minor] Colonic Neoplasms / drug therapy. Female. Humans. Middle Aged

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  • [Copyright] Copyright 2002 S. Karger AG, Basel
  • (PMID = 12053072.001).
  • [ISSN] 1660-8151
  • [Journal-full-title] Nephron
  • [ISO-abbreviation] Nephron
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11096-26-7 / Erythropoietin; 50SG953SK6 / Mitomycin
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8. Fujiwara S, Noguchi T, Suehiro S, Kikuchi R, Noguchi T, Uchida Y: [A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy]. Gan To Kagaku Ryoho; 2003 Aug;30(8):1177-81
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  • [Title] [A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy].
  • Colonoscopic examination revealed a type 2 tumor in the ascending colon.
  • We diagnosed this case as ascending colon carcinoma with multiple lung metastases, and performed right hemicolectomy and D1 lymph node dissection.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adjuvants, Immunologic / administration & dosage. Antimetabolites, Antineoplastic / administration & dosage. Cimetidine / administration & dosage. Colonic Neoplasms / drug therapy. Colonic Neoplasms / pathology. Floxuridine / administration & dosage. Histamine H2 Antagonists / administration & dosage. Lung Neoplasms / secondary
  • [MeSH-minor] Aged. Drug Therapy, Combination. Female. Humans

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  • (PMID = 12938277.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Adjuvants, Immunologic; 0 / Antimetabolites, Antineoplastic; 0 / Histamine H2 Antagonists; 039LU44I5M / Floxuridine; 80061L1WGD / Cimetidine; V1JK16Y2JP / doxifluridine
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