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1. del Rosario Usoles E, De Andrés Ibáñez J, Higueras Castellanos R: [Prolonged interscalene block to treat postoperative brachial plexopathy]. Rev Esp Anestesiol Reanim; 2004 Apr;51(4):213-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Prolonged interscalene block to treat postoperative brachial plexopathy].
  • [Transliterated title] Tratamiento de una plexopatía braquial postquirúrgica mediante bloqueo interescalénico prolongado.
  • A 47-year-old woman developed neuropathic pain in the right brachial plexus after surgery to remove a suprasellar tumor.
  • The main cause was injury to the plexus owing to technical difficulties in the preoperative catheterization of the ipsilateral internal jugular vein.
  • The pain, which was intense and refractory to systemic medication, resolved with a continuous interscalene block with ropivacaine, clonidine, and morphine.
  • Injury to the brachial plexus causes neuropathic type pain.
  • A continuous regional block of the brachial plexus to manage refractory neuropathic pain is an effective technique that is seldom mentioned in the literature.
  • [MeSH-major] Brachial Plexus Neuritis / therapy. Nerve Block. Postoperative Complications / therapy

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  • (PMID = 15168929.001).
  • [ISSN] 0034-9356
  • [Journal-full-title] Revista española de anestesiología y reanimación
  • [ISO-abbreviation] Rev Esp Anestesiol Reanim
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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2. Vranken JH, van der Vegt MH, Zuurmond WW, Pijl AJ, Dzoljic M: Continuous brachial plexus block at the cervical level using a posterior approach in the management of neuropathic cancer pain. Reg Anesth Pain Med; 2001 Nov-Dec;26(6):572-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Continuous brachial plexus block at the cervical level using a posterior approach in the management of neuropathic cancer pain.
  • BACKGROUND AND OBJECTIVES: Neuropathic cancer pain due to tumor growth near the brachial plexus is often treated with a combination of nonsteroidal anti-inflammatory drugs, tricyclic antidepressants, anticonvulsants, and oral or transdermal opioids.
  • We propose placement of a catheter along the brachial plexus using a posterior approach for patients not responding to the above-mentioned treatment.
  • Continuous administration of local anesthetics via a brachial plexus catheter inserted at the cervical level using a posterior approach resulted in a markedly improved analgesia and decreased opioid requirement.
  • CONCLUSION: Continuous brachial plexus block should be considered in patients with severe neuropathic cancer pain in the arm and shoulder.
  • To achieve sufficient pain relief for prolonged periods of time, a catheter was inserted to block the brachial plexus using a posterior approach.
  • [MeSH-major] Brachial Plexus. Neoplasms / complications. Nerve Block. Pain / drug therapy. Pain / etiology

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  • (PMID = 11707798.001).
  • [ISSN] 1098-7339
  • [Journal-full-title] Regional anesthesia and pain medicine
  • [ISO-abbreviation] Reg Anesth Pain Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Local; Y8335394RO / Bupivacaine
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3. Esch AT, Esch A, Knorr JL, Boezaart AP: Long-term ambulatory continuous nerve blocks for terminally ill patients: a case series. Pain Med; 2010 Aug;11(8):1299-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All three cases had an unfavorable coagulation status; case 2 had a prior pneumonectomy on the contralateral side and a large tumor on the ipsilateral lung of the continuous brachial plexus block.
  • RESULTS: After infusion and titration of local anesthetic doses, oral opioid medication was significantly reduced, which resulted in an improved quality of life.
  • [MeSH-major] Ambulatory Care. Nerve Block / methods. Pain / drug therapy. Terminally Ill

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  • (PMID = 20704678.001).
  • [ISSN] 1526-4637
  • [Journal-full-title] Pain medicine (Malden, Mass.)
  • [ISO-abbreviation] Pain Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Analgesics, Opioid
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4. Hakozaki M, Hojo H, Sato M, Tajino T, Yamada H, Kikuchi S, Abe M: Establishment and characterization of a novel human malignant peripheral nerve sheath tumor cell line, FMS-1, that overexpresses epidermal growth factor receptor and cyclooxygenase-2. Virchows Arch; 2009 Dec;455(6):517-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Establishment and characterization of a novel human malignant peripheral nerve sheath tumor cell line, FMS-1, that overexpresses epidermal growth factor receptor and cyclooxygenase-2.
  • Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma.
  • We established a new human MPNST cell line (designated FMS-1) from MPNST of the right brachial plexus of a 69-year-old woman with NF1.
  • FMS-1 cells showed a fibrosarcoma-like or epithelioid pattern in the heterotransplanted tumor, compared with a fascicular growth pattern of short-spindle tumor cells in the primary tumor.
  • Immunophenotypically, FMS-1 cells showed almost the same characteristics as the primary tumor.
  • To improve the highly aggressive course and poor prognosis and establish new therapeutic methods, molecular genetic and biological characterizations of MPNST are required.
  • Thus, FMS-1 cells might be useful for investigating biological behaviors and developing new molecular-targeting antitumor drugs for MPNST expressing EGFR or COX-2.
  • [MeSH-major] Cell Line, Tumor. Cyclooxygenase 2 / genetics. Nerve Sheath Neoplasms / pathology. Neurofibromatosis 1 / pathology. Receptor, Epidermal Growth Factor / genetics
  • [MeSH-minor] Aged. Animals. Brachial Plexus Neuropathies / pathology. Female. Genes, p53 / genetics. Humans. Mice. Neoplasm Transplantation. Polymorphism, Single-Stranded Conformational. Reverse Transcriptase Polymerase Chain Reaction


5. Rivera JA, Christopoulos S, Small D, Trifiro M: Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature. J Clin Endocrinol Metab; 2004 Jul;89(7):3183-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Radical interventions, such as extensive tumor debulking and oophorectomy for hormonal control, although effective in many cases, are not always possible or desirable and carry significant morbidity.
  • Here we present two cases of BMLs to illustrate the role of newer therapeutic agents, the estrogen receptor modulators and the aromatase inhibitors, in the hormonal manipulation of these tumors.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Brachial Plexus Neuropathies / drug therapy. Enzyme Inhibitors / therapeutic use. Leiomyoma / drug therapy. Leiomyoma / pathology. Lung Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Adult. Aromatase Inhibitors. Estrogen Receptor Modulators / therapeutic use. Female. Gonadotropin-Releasing Hormone / agonists. Humans. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Neoplasms / diagnosis. Neoplasms / drug therapy. Nitriles / therapeutic use. Radiography, Thoracic. Raloxifene Hydrochloride / therapeutic use. Selective Estrogen Receptor Modulators / therapeutic use. Triazoles / therapeutic use

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  • (PMID = 15240591.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Aromatase Inhibitors; 0 / Enzyme Inhibitors; 0 / Estrogen Receptor Modulators; 0 / Nitriles; 0 / Selective Estrogen Receptor Modulators; 0 / Triazoles; 2Z07MYW1AZ / anastrozole; 33515-09-2 / Gonadotropin-Releasing Hormone; 4F86W47BR6 / Raloxifene Hydrochloride
  • [Number-of-references] 53
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6. Vranken JH, Zuurmond WW, de Lange JJ: Continuous brachial plexus block as treatment for the Pancoast syndrome. Clin J Pain; 2000 Dec;16(4):327-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Continuous brachial plexus block as treatment for the Pancoast syndrome.
  • BACKGROUND: Six patients with severe neuropathic pain caused by a Pancoast tumor were treated with the continuous administration of local anesthetics.
  • These patients had not responded to any other treatment, including nonsteroidal anti-inflammatory drugs, opioids, dexamethasone, tricyclic antidepressants, anticonvulsants, ketamine, and transcutaneous electric nerve stimulation.
  • INTERVENTIONS: An axillary catheter was placed in the brachial plexus using a posterior approach that has not been described previously.
  • CONCLUSIONS: We conclude that neuropathic pain may be treated by local anesthetics administered through an axillary catheter placed in the brachial plexus.
  • [MeSH-major] Brachial Plexus. Nerve Block / methods. Neuralgia / drug therapy. Neuralgia / etiology. Pancoast Syndrome / complications
  • [MeSH-minor] Aged. Aged, 80 and over. Anesthetics, Local / administration & dosage. Axilla. Brachial Plexus Neuropathies / etiology. Brachial Plexus Neuropathies / therapy. Catheterization / methods. Female. Humans. Male. Middle Aged. Pain Measurement. Patient Satisfaction

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  • (PMID = 11153789.001).
  • [ISSN] 0749-8047
  • [Journal-full-title] The Clinical journal of pain
  • [ISO-abbreviation] Clin J Pain
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Local
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7. Ball C, Thomson KR, Kavnoudias H: Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. Anesth Analg; 2010 May 1;110(5):1305-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Bioelectrics, an interesting new area of medicine, combines pulsed high-voltage engineering with cell biology and has many potential applications.
  • METHODS: A clinical trial of IRE as a tumor ablation therapy was performed at our institution.
  • Patients required a relaxant general anesthetic.
  • CONCLUSIONS: Relaxant general anesthesia is required for IRE of the liver, lung, and kidney.
  • Attention to the position of the arms is required to maximize CT scan quality but minimize brachial plexus strain.
  • [MeSH-major] Electroporation / methods. Neoplasms / therapy
  • [MeSH-minor] Acid-Base Imbalance / etiology. Adult. Aged. Aged, 80 and over. Anesthesia, General. Anesthetics, Inhalation. Anesthetics, Intravenous. Arrhythmias, Cardiac / etiology. Electrocardiography. Electrodes. Electroencephalography / drug effects. Female. Humans. Hypertension / etiology. Isoflurane. Male. Middle Aged. Muscle, Skeletal / physiology. Neoplasm Metastasis / therapy. Pain, Postoperative / epidemiology. Pneumothorax / etiology. Propofol. Tomography, X-Ray Computed. Water-Electrolyte Imbalance / etiology

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  • [CommentIn] Anesth Analg. 2010 May 1;110(5):1264 [20418290.001]
  • (PMID = 20142349.001).
  • [ISSN] 1526-7598
  • [Journal-full-title] Anesthesia and analgesia
  • [ISO-abbreviation] Anesth. Analg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Inhalation; 0 / Anesthetics, Intravenous; CYS9AKD70P / Isoflurane; YI7VU623SF / Propofol
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8. Hoşten T, Gürkan Y, Solak M, Toker K: A case of Horner's syndrome following lateral sagittal infraclavicular block. Agri; 2008 Oct;20(4):45-8
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  • Horner's Syndrome results from paralysis of the ipsilateral sympathetic cervical chain (stellate ganglion) caused by surgery, drugs (mainly high concentrations of local anesthetics), local compression (hematoma or tumor), or inadequate perioperative positioning of the patient.
  • It occurs in 100 % of the patients with an interscalene block of the brachial plexus and can also occur in patients with other types of supraclavicular blocks.
  • [MeSH-minor] Adult. Brachial Plexus. Fracture Fixation, Internal. Humans. Humeral Fractures / surgery. Male. Radius Fractures / surgery

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  • (PMID = 19117156.001).
  • [ISSN] 1300-0012
  • [Journal-full-title] Aǧrı : Ağrı (Algoloji) Derneği'nin Yayın organıdır = The journal of the Turkish Society of Algology
  • [ISO-abbreviation] Agri
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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9. Koukourakis MI, Yannakakis D: High dose daily amifostine and hypofractionated intensively accelerated radiotherapy for locally advanced breast cancer. A phase I/II study and report on early and late sequellae. Anticancer Res; 2001 Jul-Aug;21(4B):2973-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intrinsic radioresistance, tumor hypoxia and ability of cancer cells to undergo rapid repopulation during radiotherapy are associated with failure of radiotherapy.
  • Although the therapeutic efficacy of accelerated regimens based on low-dose per fraction may be high since they minimize the adverse role of rapid tumor repopulation, the cellular compartment with low alpha/beta-ratio values (i.e. hypoxic cells) remains a limiting factor.
  • None of these patients showed any signs of late sequellae, such as lung and myoskeletal fibrosis, or brachial plexopathy.
  • [MeSH-major] Amifostine / administration & dosage. Breast Neoplasms / radiotherapy. Radiation Injuries / prevention & control. Radiation-Protective Agents / administration & dosage. Radiotherapy, High-Energy / methods
  • [MeSH-minor] Adult. Aged. Arm / pathology. Brachial Plexus / radiation effects. Breast / pathology. Dose Fractionation. Drug Administration Schedule. Edema / etiology. Feasibility Studies. Female. Fibrosis. Humans. Hypotension / chemically induced. Middle Aged. Peripheral Nervous System Diseases / etiology. Pulmonary Fibrosis / etiology. Radiation Pneumonitis / etiology. Radiodermatitis / etiology. Severity of Illness Index. Survival Analysis. Treatment Outcome. Vomiting / chemically induced

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  • (PMID = 11712796.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Clinical Trial; Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Radiation-Protective Agents; M487QF2F4V / Amifostine
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