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1. Lee YC, Lee JW: Innovative treatment for huge nuchal desmoid tumour: a case report with a 2-year follow-up. J Plast Reconstr Aesthet Surg; 2010 Aug;63(8):e622-6
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  • BACKGROUND: The desmoid tumour is a monoclonal neoplasm originating from musculoaponeurotic tissues.
  • Surgical resection, radiotherapy, chemotherapy, hormonal therapy, non-steroidal anti-inflammatory drugs and even a wait-and-see policy, either alone or in combination, were advocated as treatment modalities.
  • Its intimacy with the carotid artery, jugular vein and brachial plexus made margin-free resection infeasible.
  • [MeSH-major] Embolization, Therapeutic / methods. Fibromatosis, Aggressive / therapy. Head and Neck Neoplasms / therapy. Suture Techniques / instrumentation. Tourniquets

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  • [Copyright] Copyright 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20304713.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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2. Krarup C, Crone C: Neurophysiological studies in malignant disease with particular reference to involvement of peripheral nerves. J Neurol; 2002 Jun;249(6):651-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Neurological and neuromuscular disorders are frequent complications in patients with neoplasms and may involve the neuromuscular system, including motor and sensory nerve cell bodies, axons, myelin, neuromuscular transmission and muscle alone or in combination.
  • Electrophysiological studies are of value in delineating the type, degree and extent of involvement, and may be of assistance in pointing towards the underlying cause: paraneoplastic factors, treatment with chemotherapy or radiation or metastatic infiltration.
  • Even in cases where such studies are obtained, a final diagnosis may only be ascertained during follow up, since the neuromuscular disorders frequently occur before the neoplasm is detected.
  • [MeSH-major] Central Nervous System Diseases / etiology. Meningeal Neoplasms / secondary. Neoplasm Metastasis / physiopathology. Neoplasms / complications. Paraneoplastic Polyneuropathy / physiopathology
  • [MeSH-minor] Animals. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Brachial Plexus Neuropathies / etiology. Brachial Plexus Neuropathies / pathology. Brachial Plexus Neuropathies / physiopathology. Humans. Lumbosacral Plexus / drug effects. Lumbosacral Plexus / physiopathology. Lumbosacral Plexus / radiation effects. Neural Conduction / physiology. Radiotherapy / adverse effects

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  • (PMID = 12111295.001).
  • [ISSN] 0340-5354
  • [Journal-full-title] Journal of neurology
  • [ISO-abbreviation] J. Neurol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Number-of-references] 113
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3. Boes M, Pels H, Klockgether T, Koch A, Schlegel U: High-grade B-cell NHL of the brachial plexus followed by infiltration of the spinal cord. J Neurol; 2008 Jan;255(1):135-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High-grade B-cell NHL of the brachial plexus followed by infiltration of the spinal cord.
  • [MeSH-major] Brachial Plexus Neuropathies / etiology. Brachial Plexus Neuropathies / pathology. Lymphoma, B-Cell / complications. Lymphoma, B-Cell / pathology. Neoplasm Invasiveness / pathology. Spinal Cord Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Arm / innervation. Arm / physiopathology. Brachial Plexus / pathology. Brachial Plexus / physiopathology. Cavernous Sinus Thrombosis / etiology. Cavernous Sinus Thrombosis / pathology. Cavernous Sinus Thrombosis / physiopathology. Cranial Nerve Diseases / etiology. Cranial Nerve Diseases / pathology. Cranial Nerve Diseases / physiopathology. Fatal Outcome. Female. Ganglia, Spinal / pathology. Ganglia, Spinal / physiopathology. Humans. Magnetic Resonance Imaging. Middle Aged. Muscle Weakness / etiology. Muscle Weakness / physiopathology. Neoplasm Metastasis / drug therapy. Neoplasm Metastasis / pathology. Neoplasm Metastasis / physiopathology. Spinal Cord / pathology. Spinal Cord / physiopathology. Spinal Nerve Roots / pathology. Spinal Nerve Roots / physiopathology. Treatment Failure

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  • [Cites] Am J Surg Pathol. 2000 Sep;24(9):1257-65 [10976700.001]
  • [Cites] Neurosurgery. 1997 Mar;40(3):618-21; discussion 621-2 [9055305.001]
  • [Cites] J Neurosurg. 2000 Jan;92(1):165-9 [10616097.001]
  • [Cites] Auris Nasus Larynx. 1999 Jul;26(3):337-42 [10419043.001]
  • [Cites] J Clin Oncol. 2003 Dec 15;21(24):4471-3 [14597745.001]
  • (PMID = 17994311.001).
  • [ISSN] 0340-5354
  • [Journal-full-title] Journal of neurology
  • [ISO-abbreviation] J. Neurol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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4. Ball C, Thomson KR, Kavnoudias H: Irreversible electroporation: a new challenge in "out of operating theater" anesthesia. Anesth Analg; 2010 May 1;110(5):1305-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Bioelectrics, an interesting new area of medicine, combines pulsed high-voltage engineering with cell biology and has many potential applications.
  • METHODS: A clinical trial of IRE as a tumor ablation therapy was performed at our institution.
  • Patients required a relaxant general anesthetic.
  • CONCLUSIONS: Relaxant general anesthesia is required for IRE of the liver, lung, and kidney.
  • Attention to the position of the arms is required to maximize CT scan quality but minimize brachial plexus strain.
  • [MeSH-major] Electroporation / methods. Neoplasms / therapy
  • [MeSH-minor] Acid-Base Imbalance / etiology. Adult. Aged. Aged, 80 and over. Anesthesia, General. Anesthetics, Inhalation. Anesthetics, Intravenous. Arrhythmias, Cardiac / etiology. Electrocardiography. Electrodes. Electroencephalography / drug effects. Female. Humans. Hypertension / etiology. Isoflurane. Male. Middle Aged. Muscle, Skeletal / physiology. Neoplasm Metastasis / therapy. Pain, Postoperative / epidemiology. Pneumothorax / etiology. Propofol. Tomography, X-Ray Computed. Water-Electrolyte Imbalance / etiology

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  • [CommentIn] Anesth Analg. 2010 May 1;110(5):1264 [20418290.001]
  • (PMID = 20142349.001).
  • [ISSN] 1526-7598
  • [Journal-full-title] Anesthesia and analgesia
  • [ISO-abbreviation] Anesth. Analg.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, Inhalation; 0 / Anesthetics, Intravenous; CYS9AKD70P / Isoflurane; YI7VU623SF / Propofol
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5. Rivera JA, Christopoulos S, Small D, Trifiro M: Hormonal manipulation of benign metastasizing leiomyomas: report of two cases and review of the literature. J Clin Endocrinol Metab; 2004 Jul;89(7):3183-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Radical interventions, such as extensive tumor debulking and oophorectomy for hormonal control, although effective in many cases, are not always possible or desirable and carry significant morbidity.
  • Here we present two cases of BMLs to illustrate the role of newer therapeutic agents, the estrogen receptor modulators and the aromatase inhibitors, in the hormonal manipulation of these tumors.
  • [MeSH-major] Antineoplastic Agents, Hormonal / therapeutic use. Brachial Plexus Neuropathies / drug therapy. Enzyme Inhibitors / therapeutic use. Leiomyoma / drug therapy. Leiomyoma / pathology. Lung Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Adult. Aromatase Inhibitors. Estrogen Receptor Modulators / therapeutic use. Female. Gonadotropin-Releasing Hormone / agonists. Humans. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Neoplasms / diagnosis. Neoplasms / drug therapy. Nitriles / therapeutic use. Radiography, Thoracic. Raloxifene Hydrochloride / therapeutic use. Selective Estrogen Receptor Modulators / therapeutic use. Triazoles / therapeutic use

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  • (PMID = 15240591.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Aromatase Inhibitors; 0 / Enzyme Inhibitors; 0 / Estrogen Receptor Modulators; 0 / Nitriles; 0 / Selective Estrogen Receptor Modulators; 0 / Triazoles; 2Z07MYW1AZ / anastrozole; 33515-09-2 / Gonadotropin-Releasing Hormone; 4F86W47BR6 / Raloxifene Hydrochloride
  • [Number-of-references] 53
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6. Pitz CC, de la Rivière AB, van Swieten HA, Duurkens VA, Lammers JW, van den Bosch JM: Surgical treatment of Pancoast tumours. Eur J Cardiothorac Surg; 2004 Jul;26(1):202-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Due to its localisation in the apex of the lung with invasion of the lower part of the brachial plexus, first ribs, vertebrae, subclavian vessels or stellate ganglion, a superior sulcus tumour causes characteristic symptoms, like arm or shoulder pain or Horner's syndrome.
  • This method facilitates better exposure of the extreme apex of the lung, brachial plexus and subclavian vessels.
  • Also the addition of other chemotherapy agents or biologic agents such as angiogenesis inhibitors or tyrosine kinase inhibitors gives a new perspective in the treatment of Pancoast tumours.
  • [MeSH-minor] Combined Modality Therapy. Humans. Neoplasm Recurrence, Local. Neoplasm Staging. Prognosis. Survival Analysis. Treatment Outcome

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  • (PMID = 15201002.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 54
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7. Sekar R, Stone PR: Trastuzumab use for metastatic breast cancer in pregnancy. Obstet Gynecol; 2007 Aug;110(2 Pt 2):507-10
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Antineoplastic Agents / therapeutic use. Breast Neoplasms / drug therapy. Carcinoma, Ductal, Breast / drug therapy. Oligohydramnios / chemically induced. Pregnancy Complications, Neoplastic / drug therapy
  • [MeSH-minor] Adult. Antibodies, Monoclonal, Humanized. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Brachial Plexus Neuropathies / drug therapy. Chemotherapy, Adjuvant. Female. Humans. Infant, Newborn. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Neoplasm Staging. Pregnancy. Pregnancy Outcome. Taxoids / adverse effects. Taxoids / therapeutic use. Trastuzumab


8. Macchiarini P: Resection of superior sulcus carcinomas (anterior approach). Thorac Surg Clin; 2004 May;14(2):229-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is hoped that, in the future, resection of disease invasion of the brachial plexus above C7 will be technically feasible [33], and that new drugs will reduce the risk of systemic relapse after resection.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / surgery. Lung Neoplasms / surgery. Pancoast Syndrome / surgery. Pneumonectomy / methods. Thoracotomy / methods
  • [MeSH-minor] Clavicle / surgery. Female. Humans. Magnetic Resonance Imaging / methods. Male. Neoplasm Staging. Prognosis. Risk Assessment. Sternum / surgery. Survival Analysis. Tomography, X-Ray Computed / methods. Treatment Outcome. Ultrasonography, Doppler

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  • (PMID = 15382299.001).
  • [ISSN] 1547-4127
  • [Journal-full-title] Thoracic surgery clinics
  • [ISO-abbreviation] Thorac Surg Clin
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 31
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9. Molloy FM, Floeter MK, Syed NA, Sandbrink F, Culcea E, Steinberg SM, Dahut W, Pluda J, Kruger EA, Reed E, Figg WD: Thalidomide neuropathy in patients treated for metastatic prostate cancer. Muscle Nerve; 2001 Aug;24(8):1050-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [MeSH-major] Peripheral Nervous System Diseases / chemically induced. Peripheral Nervous System Diseases / diagnosis. Prostatic Neoplasms / drug therapy. Thalidomide / adverse effects
  • [MeSH-minor] Action Potentials / drug effects. Age Factors. Aged. Aged, 80 and over. Brachial Plexus / drug effects. Brachial Plexus / physiopathology. Cohort Studies. Dose-Response Relationship, Drug. Electrodiagnosis. Electromyography. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neural Conduction / drug effects. Neurons, Afferent / drug effects. Prospective Studies. Risk Factors. Sural Nerve / drug effects. Sural Nerve / physiopathology


10. Hakozaki M, Hojo H, Sato M, Tajino T, Yamada H, Kikuchi S, Abe M: Establishment and characterization of a novel human malignant peripheral nerve sheath tumor cell line, FMS-1, that overexpresses epidermal growth factor receptor and cyclooxygenase-2. Virchows Arch; 2009 Dec;455(6):517-26
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Establishment and characterization of a novel human malignant peripheral nerve sheath tumor cell line, FMS-1, that overexpresses epidermal growth factor receptor and cyclooxygenase-2.
  • Malignant peripheral nerve sheath tumor (MPNST) is a rare soft tissue sarcoma.
  • We established a new human MPNST cell line (designated FMS-1) from MPNST of the right brachial plexus of a 69-year-old woman with NF1.
  • FMS-1 cells showed a fibrosarcoma-like or epithelioid pattern in the heterotransplanted tumor, compared with a fascicular growth pattern of short-spindle tumor cells in the primary tumor.
  • Immunophenotypically, FMS-1 cells showed almost the same characteristics as the primary tumor.
  • To improve the highly aggressive course and poor prognosis and establish new therapeutic methods, molecular genetic and biological characterizations of MPNST are required.
  • Thus, FMS-1 cells might be useful for investigating biological behaviors and developing new molecular-targeting antitumor drugs for MPNST expressing EGFR or COX-2.
  • [MeSH-major] Cell Line, Tumor. Cyclooxygenase 2 / genetics. Nerve Sheath Neoplasms / pathology. Neurofibromatosis 1 / pathology. Receptor, Epidermal Growth Factor / genetics
  • [MeSH-minor] Aged. Animals. Brachial Plexus Neuropathies / pathology. Female. Genes, p53 / genetics. Humans. Mice. Neoplasm Transplantation. Polymorphism, Single-Stranded Conformational. Reverse Transcriptase Polymerase Chain Reaction






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