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1. Watanabe Y, Itoh S, Mitsuhata N: [Urachal carcinoma treated with neoadjuvant intra-arterial chemotherapy: a case report]. Hinyokika Kiyo; 2004 Oct;50(10):713-6
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  • [Title] [Urachal carcinoma treated with neoadjuvant intra-arterial chemotherapy: a case report].
  • Ultrasonography and computed tomography demonstrated a tumor at the bladder dome.
  • Cold punch biopsy revealed well-differentiated adenocarcinoma and stage III A urachal carcinoma was diagnosed.
  • Augmentation ilealcystoplasty was subsequently performed to secure bladder capacity.
  • [MeSH-major] Adenocarcinoma, Papillary / drug therapy. Antineoplastic Agents / administration & dosage. Tegafur / administration & dosage. Urachus. Uracil / administration & dosage
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant. Drug Administration Schedule. Drug Combinations. Humans. Infusions, Intra-Arterial. Male

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  • (PMID = 15575224.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Drug Combinations; 0 / UFT(R) drug; 1548R74NSZ / Tegafur; 56HH86ZVCT / Uracil
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2. Hasegawa Y, Kato Y, Wakita T, Hayashi N, Tsukamoto K: [Carcinoma of the urachus: a case report]. Hinyokika Kiyo; 2005 Mar;51(3):191-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cystoscopy revealed a broad-stalk, nonpapillary tumor at the urinary bladder dome, and cold-punch biopsy proved it to be a mucus-producing adenocarcinoma.
  • Abdominal managnetic resonance imaging demonstrated a tumor extending from the umbilicus to the bladder dome, and chest computed tomography (CT) demonstrated a small lung tumor with calcification.
  • We therefore diagnosed an urachal carcinoma with lung metastases.
  • Total cystectomy, umbilical-urachal resection, hysterectomy, ileal neobladder, and partial resection of lung were performed, followed by partial resection of the left lung using thoracoscopy.
  • [MeSH-major] Adenocarcinoma, Mucinous / drug therapy. Adenocarcinoma, Mucinous / surgery. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Urachus
  • [MeSH-minor] Adult. Carboplatin / administration & dosage. Combined Modality Therapy. Cystectomy. Drug Administration Schedule. Female. Humans. Hysterectomy. Lung Neoplasms / secondary. Lung Neoplasms / surgery. Paclitaxel / administration & dosage

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  • (PMID = 15852675.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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3. Tran B, McKendrick J: Metastatic urachal cancer responding to FOLFOX chemotherapy. Can J Urol; 2010 Apr;17(2):5120-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic urachal cancer responding to FOLFOX chemotherapy.
  • Metastatic urachal cancer is a rare disease and subsequently, does not have a defined systemic treatment.
  • Although urachal cancer is most commonly adenocarcinoma and histologically similar to colon cancer, treatment selection is usually based upon location (the proximity of the urachus to the bladder) with bladder cancer regimens the most commonly prescribed.
  • We report a case of metastatic urachal cancer where the immunohistochemical profile's similarities to colon cancer led to treatment with colon cancer specific chemotherapy.
  • Our case is the first to report urachal cancer treated with and responding to modified FOLFOX6.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Urachus / pathology. Urinary Bladder Neoplasms / drug therapy
  • [MeSH-minor] Combined Modality Therapy. Cystectomy. Fluorouracil / administration & dosage. Humans. Leucovorin / administration & dosage. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Male. Middle Aged. Organoplatinum Compounds / administration & dosage. Thyroid Neoplasms / drug therapy. Thyroid Neoplasms / secondary. Treatment Outcome

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  • (PMID = 20398453.001).
  • [ISSN] 1195-9479
  • [Journal-full-title] The Canadian journal of urology
  • [ISO-abbreviation] Can J Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Organoplatinum Compounds; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; Folfox protocol
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4. Kojima Y, Yamada Y, Kamisawa H, Sasaki S, Hayashi Y, Kohri K: Complete response of a recurrent advanced urachal carcinoma treated by S-1/cisplatin combination chemotherapy. Int J Urol; 2006 Aug;13(8):1123-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Complete response of a recurrent advanced urachal carcinoma treated by S-1/cisplatin combination chemotherapy.
  • We report a case of recurrent advanced urachal carcinoma with right internal iliac node and left lung metastases in a 34-year-old man.
  • S-1/cisplatin combination chemotherapy is suggested to be a potent tool for controlling advanced urachal carcinoma.
  • [MeSH-major] Adenocarcinoma / drug therapy. Adenocarcinoma / secondary. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Lung Neoplasms / drug therapy. Lung Neoplasms / secondary. Urachus. Urinary Bladder Neoplasms / drug therapy. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Adult. Cisplatin / administration & dosage. Drug Combinations. Hematuria / etiology. Humans. Iliac Artery. Lymph Node Excision. Lymphatic Metastasis. Male. Oxonic Acid / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 16903943.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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5. Mohile SG, Schleicher L, Petrylak DP: Treatment of metastatic urachal carcinoma in an elderly woman. Nat Clin Pract Oncol; 2008 Jan;5(1):55-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of metastatic urachal carcinoma in an elderly woman.
  • Imaging revealed a large pelvic mass situated on the dome of the bladder, extending from the urachus, without evidence of other sites of metastases.
  • After resection, urachal adenocarcinoma was histologically confirmed.
  • DIAGNOSIS: Metastatic urachal adenocarcinoma.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Carcinoma, Signet Ring Cell / secondary. Cystectomy. Lymph Node Excision. Pelvic Neoplasms / secondary. Urachus. Urinary Bladder Neoplasms / surgery
  • [MeSH-minor] Aged. Camptothecin / administration & dosage. Camptothecin / analogs & derivatives. Combined Modality Therapy. Diagnosis, Differential. Female. Fluorouracil / administration & dosage. Humans. Leucovorin / administration & dosage. Neoplasm Recurrence, Local / drug therapy. Neoplasm Recurrence, Local / radiotherapy. Neoplasm Recurrence, Local / surgery. Radiotherapy, Adjuvant

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  • (PMID = 18097457.001).
  • [ISSN] 1743-4262
  • [Journal-full-title] Nature clinical practice. Oncology
  • [ISO-abbreviation] Nat Clin Pract Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 7673326042 / irinotecan; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil; XT3Z54Z28A / Camptothecin; IFL protocol
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6. Sekita N, Fujimura M, Arai H, Shibata N, Nishikawa R, Sugano I, Mikami K: [A case of urachal carcinoma treated with S-1/CDDP combination chemotherapy]. Hinyokika Kiyo; 2010 Aug;56(8):447-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A case of urachal carcinoma treated with S-1/CDDP combination chemotherapy].
  • No established treatment exists for urachal carcinoma,except curative resection,and its prognosis is poor.
  • More than 80% of urachal carcinomas are adenocarcinomas.
  • We report a case of advanced urachal carcinoma treated with S-1 and cisplatin combination (S-1/CDDP) chemotherapy.
  • A tumor was detected on the bladder dome and transurethral resection was performed.
  • Histopathological findings indicated poorly differentiated adenocarcinoma.
  • The tumor was diagnosed as stage IVB (Sheldon's category) urachal carcinoma.
  • After one cycle of S-1/CDDP chemotherapy,the size of the tumor on the bladder dome decreased,after which total cystectomy was performed.
  • The surgical margin of the cystectomy specimen was negative for malignant cells,although poorly differentiated adenocarcinoma was still observed in this specimen.
  • The findings of this study indicate that this therapy might be beneficial for treating advanced urachal carcinomas.
  • This is the second report of successful treatment of advanced urachal carcinoma with S-1/CDDP chemotherapy.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Urachus / abnormalities. Urinary Bladder Neoplasms / drug therapy
  • [MeSH-minor] Antimetabolites, Antineoplastic / administration & dosage. Antineoplastic Agents / administration & dosage. Cisplatin / administration & dosage. Combined Modality Therapy. Cystectomy. Drug Combinations. Female. Humans. Middle Aged. Oxonic Acid / administration & dosage. Tegafur / administration & dosage

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  • (PMID = 20808064.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents; 0 / Drug Combinations; 150863-82-4 / S 1 (combination); 1548R74NSZ / Tegafur; 5VT6420TIG / Oxonic Acid; Q20Q21Q62J / Cisplatin
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