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1. Guthrie BD, Adler MD, Powell EC: Incidence and trends of pediatric ovarian torsion hospitalizations in the United States, 2000-2006. Pediatrics; 2010 Mar;125(3):532-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All females aged 1 to 20 years who were hospitalized with ovarian torsion in states participating in KID 2000, KID 2003, and KID 2006 representing 900, 1224, and 1232 ovarian torsion-related hospitalizations, respectively, were included.
  • A diagnosis of benign neoplasm increased the adjusted odds of oophorectomy by 2.16.
  • Fewer than 0.5% of ovarian torsion hospitalizations were associated with malignant neoplasm.
  • CONCLUSIONS: Nationally representative hospital data indicate that ovarian torsion is uncommon but occurs in all ages and is typically associated with normal ovaries or benign lesions.

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  • (PMID = 20123766.001).
  • [ISSN] 1098-4275
  • [Journal-full-title] Pediatrics
  • [ISO-abbreviation] Pediatrics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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2. Chung SM, Kim HS, Jung J, Lee HK, Lee WS: Clinical presentation and management of jugular foramen paraganglioma. Clin Exp Otorhinolaryngol; 2009 Mar;2(1):28-32
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  • OBJECTIVES: Jugular foramen paraganglioma is a locally invasive, benign tumor, which grow slowly and causes various symptoms such as pulsatile tinnitus and low cranial nerve palsy.
  • Seven patients were classified as Fisch Type C tumor and remaining 2 as Fisch Type D tumor on radiologic examination.
  • Angiography with embolization is crucial for successful tumor removal without massive bleeding.

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  • [Cites] J Neurosurg. 1994 Jun;80(6):1026-38 [8189258.001]
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  • (PMID = 19434288.001).
  • [ISSN] 1976-8710
  • [Journal-full-title] Clinical and experimental otorhinolaryngology
  • [ISO-abbreviation] Clin Exp Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2671826
  • [Keywords] NOTNLM ; Combined approach / Infratemporal approach / Intracranial extension / Jugular foramen paraganglioma
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3. John BJ, Griffiths C, Ebbs SR: Pleomorphic adenoma of the breast should be excised with a cuff of normal tissue. Breast J; 2007 Jul-Aug;13(4):418-20
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  • Pleomorphic adenoma is a benign tumor found rarely in the breast but commonly in the salivary gland.
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Recurrence, Local / surgery

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  • (PMID = 17593049.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 12
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4. Yamaguchi T, Sakagoshi N, Kobayashi Y: [Papillary fibroelastoma which occurred from the posterior leaflet of the mitral valve; report of a case]. Kyobu Geka; 2007 Feb;60(2):153-5
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  • Papillary fibroelastoma is a rare benign tumor arising from the cardiac endothelium.
  • Echocardiography revealed massive pericardial effusion and a small tumor attached to the posterior mitral leaflet.
  • We excised the tumor including a part of the posterior mitral leaflet, and mitral valve plasty was done.

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  • (PMID = 17305083.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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5. Ayadi-Kaddour A, Saïji E, Ben Slama S, Chelly-Ennaiffer I, Lahmar-Boufaroua A, Goutallier-Ben Fadhel C, Ben Sassi L, Khalfallah MT, Mzabi-Regaya S: [Hepatic mesenchymal hamartoma in adulthood: a case report with literature review]. Tunis Med; 2006 Apr;84(4):263-5
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  • Mesenchymal hamartoma is a rare and benign tumor..
  • Abdominal US and CTscan exminations showed a medial liver tumor with cystic formations suggestive of a hydatid cyst.
  • Treatment is surgical involving in most of the cases; a wide hepatic resection because of the size of the tumor.

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  • (PMID = 16833000.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Tunisia
  • [Number-of-references] 11
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6. Soyer T, Karnak I, Talim B, Tanyel FC: Aneurysmal bone cyst of the rib in a child: report of a case. Surg Today; 2005;35(10):886-9
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  • An aneurysmal bone cyst (ABC) is a benign tumor of the skeletal system, which is rare in childhood and mostly occurs in long bones.

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  • [Cites] Chir Pediatr. 1990;31(3):152-6 [2081362.001]
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  • (PMID = 16175473.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
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7. O'Malley BW Jr, Weinstein GS: Robotic skull base surgery: preclinical investigations to human clinical application. Arch Otolaryngol Head Neck Surg; 2007 Dec;133(12):1215-9
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  • Based on the preclinical work, transoral robotic surgery (TORS) was then performed in February 2007 on 1 human patient with a parapharyngeal to infratemporal fossa cystic neoplasm as part of a large prospective human trial.
  • For the human surgical case, a TORS approach was evaluated on one side for a benign neoplasm.
  • PATIENTS: For the human clinical trial, a TORS approach was evaluated for a patient with a benign neoplasm of the parapharyngeal space and infratemporal fossa.
  • In the first known human surgical case, TORS was used to remove a parapharyngeal space and infratemporal fossa cystic neoplasm.

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  • (PMID = 18086962.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
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8. Reich O, Gratzke C, Bachmann A, Seitz M, Schlenker B, Hermanek P, Lack N, Stief CG, Urology Section of the Bavarian Working Group for Quality Assurance: Morbidity, mortality and early outcome of transurethral resection of the prostate: a prospective multicenter evaluation of 10,654 patients. J Urol; 2008 Jul;180(1):246-9
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  • PURPOSE: Transurethral resection of the prostate has for decades been the standard surgical therapy for lower urinary tract symptoms secondary to benign prostatic hyperplasia, the most common benign neoplasm in men.
  • This most contemporary information should be of use to potential patients and facilitate subsumption of emerging surgical and nonsurgical benign prostatic hyperplasia treatment options.

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  • [CommentIn] J Urol. 2008 Jul;180(1):15-6 [18485411.001]
  • (PMID = 18499179.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
  • [Investigator] Altwein J; Hartung R; Klotz T; Kriegmair M; Liedl B; Ottmann K; Burmeister C
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9. Heinrich UR, Brieger J, Gosepath J, Wierzbicka M, Sokolov M, Roth Y, Szyfter W, Bittinger F, Mann WJ: Frequent chromosomal gains in recurrent juvenile nasopharyngeal angiofibroma. Cancer Genet Cytogenet; 2007 Jun;175(2):138-43
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor, mostly affecting adolescent males.
  • Four patients with one or two recurrences were included in the study; for one of these, no material of the primary tumor was available for analysis.
  • There was no correlation among tumor staging, age, and DNA amplification.
  • No DNA aneuploidy was detected, a finding in accordance with the generally benign characteristics of JNAs.
  • Our observations suggest that in JNA the activation of oncogenes is more likely than the inactivation of tumor suppressor genes.
  • Autosomal gains in the primary tumor should be further evaluated as markers for a potentially increased risk of recurrence after surgical removal in this entity.
  • [MeSH-major] Angiofibroma / genetics. Chromosome Aberrations. Nasopharyngeal Neoplasms / genetics. Neoplasm Recurrence, Local / genetics

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  • (PMID = 17556070.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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10. Taniura T, Marukawa K, Yamada K, Hikasa Y, Ito K: Differential diagnosis of hepatic tumor-like lesions in dog by using dynamic CT scanning. Hiroshima J Med Sci; 2009 Mar;58(1):17-24
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  • [Title] Differential diagnosis of hepatic tumor-like lesions in dog by using dynamic CT scanning.
  • Dynamic liver CT scanning is used to observe the hemodynamics of hepatic tumor-like lesions by taking images sequentially after administration of contrast media.
  • In this study in dogs, we compared the hemodynamic patterns of hepatocellular carcinoma (HCC), one of the malignant tumors, and nodular hyperplasia (NH), a benign tumor that is more common in older dogs.
  • Dynamic liver CT scanning can therefore be considered a useful technique in the differential diagnosis of hepatic tumor-like lesions in dogs.

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  • (PMID = 19400553.001).
  • [ISSN] 0018-2052
  • [Journal-full-title] Hiroshima journal of medical sciences
  • [ISO-abbreviation] Hiroshima J. Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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11. Ławicki S, Czygier M, Bedkowska E, Wojtukiewicz M, Szmitkowski M: Comparative evaluation of plasma levels and diagnostic values of macrophage-colony stimulating factor in patients with breast cancer and benign tumors. Pol Arch Med Wewn; 2008 Sep;118(9):464-9
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  • [Title] Comparative evaluation of plasma levels and diagnostic values of macrophage-colony stimulating factor in patients with breast cancer and benign tumors.
  • The direct production of this cytokine has been reported in tumor cell lines in vitro and in solid tumors in vivo.
  • OBJECTIVES: In the present study, the levels of M-CSF in patients with breast cancer and in those with a benign breast tumor were evaluated.
  • PATIENTS AND METHODS: The study group was made up of 70 patients with breast cancer and 20 patients with benign tumors and the control group of 30 healthy women.
  • RESULTS: Statistically higher levels of M-CSF and CA 15-3 were found in breast cancer patients as compared to the benign tumor and control groups.
  • CONCLUSIONS: The above data suggests that M-CSF might be useful in both diagnostics and differential diagnosis of benign tumors and breast cancer (except for the lowest degree of the clinical progression).
  • [MeSH-major] Biomarkers, Tumor / blood. Breast Neoplasms / blood. Breast Neoplasms / diagnosis. Macrophage Colony-Stimulating Factor / blood
  • [MeSH-minor] Adult. Aged. CA-125 Antigen / blood. Enzyme-Linked Immunosorbent Assay. Female. Humans. Middle Aged. Neoplasm Staging. Poland. Predictive Value of Tests. Sensitivity and Specificity

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  • (PMID = 18846980.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 81627-83-0 / Macrophage Colony-Stimulating Factor
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12. Giorgi Rossi P, Chini F, Barca A, Baiocchi D, Federici A, Farchi S, Borgia P: Efficacy of disease management profiles. The mammographic screening program of Lazio. Tumori; 2008 May-Jun;94(3):297-303
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  • Screening histories of all the incident cases of women surgically treated for a breast neoplasm were reconstructed (not contacted, contacted, non-participants, participants).
  • RESULTS: We identified 3251 women who were treated for malignant neoplasms of the breast and 1562 treated for benign neoplasms.
  • CONCLUSIONS: The first round of screening programs led to more surgical interventions, a similar incidence of mastectomy and of interventions for benign neoplasm, but a lower incidence of unnecessary treatment.
  • [MeSH-minor] Aged. Carcinoma in Situ / diagnostic imaging. Carcinoma in Situ / surgery. Early Diagnosis. Female. Humans. Incidence. Italy / epidemiology. Middle Aged. Neoplasm Staging. Odds Ratio. Program Evaluation. Research Design

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  • (PMID = 18705394.001).
  • [ISSN] 0300-8916
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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13. Cherekaev VA, Gol'bin DA, Kapitanov DN, Belov AI, Arustamian SR, Gromova VV, Imaev AA: [Surgical treatment of extensive craniofacial juvenile angiofibromas]. Zh Vopr Neirokhir Im N N Burdenko; 2009 Apr-Jun;(2):9-14; discussion 14-5
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a rare benign tumor occurring almost exclusively in adolescent and young adult males.
  • The tumor is characterized by slow progression, aggressive growth, high vascularization and increased rate of persistence and recurrence.
  • 4 cases are presented (3 patients with Fisch grade IV tumor and 1 with grade III).

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  • (PMID = 19569543.001).
  • [ISSN] 0042-8817
  • [Journal-full-title] Zhurnal voprosy neĭrokhirurgii imeni N. N. Burdenko
  • [ISO-abbreviation] Zh Vopr Neirokhir Im N N Burdenko
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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14. Zhu DD, Yang ZQ: [Surgical treatment of transclavicular and transsternal tumor]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2006 Nov;41(11):848-50
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  • [Title] [Surgical treatment of transclavicular and transsternal tumor].
  • OBJECTIVE: To investigate surgical treatment approach of transclavicular and transsternal tumor.
  • METHODS: Twelve cases of neck-root and mediastinum thoracis tumor subjected to cervicothoracic-combined surgical treatment were retrospectively analyzed and summarized.
  • RESULTS: Seven cases of benign tumor survived 1-8 years after surgery.
  • The other 5 patients were malignant tumor.
  • CONCLUSIONS: The evaluation of twelve cases of transclavicular and transsternal tumor with adoption of cervicothoracic-combined surgical approach improves and develops traditional knowledge of surgical therapy of neck-root tumors.

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  • (PMID = 17283540.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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15. Gallana-Alvarez S, Mayorga-Jimenez F, Torres-Gómez FJ, Avellá-Vecino FJ, Salazar-Fernandez C: Calcifying odontogenic cyst associated with complex odontoma: case report and review of the literature. Med Oral Patol Oral Cir Bucal; 2005 May-Jul;10(3):243-7
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  • The lesion is a mixed odontogenic benign tumor, and although most of the cases present cystic characteristics, a few are of the solid type (15%), and its rare malignant transformation is well documented.

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  • (PMID = 15876968.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 26
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16. Chakhachiro ZI, Zaatari G: Solid-pseudopapillary neoplasm: a pancreatic enigma. Arch Pathol Lab Med; 2009 Dec;133(12):1989-93
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  • [Title] Solid-pseudopapillary neoplasm: a pancreatic enigma.
  • Solid-pseudopapillary neoplasm of the pancreas is a relatively uncommon tumor.
  • Although previously considered benign, this tumor is currently considered a low-grade malignant epithelial neoplasm with low metastatic rate and high overall survival.
  • Despite the characterization of the morphologic and molecular features of this enigmatic neoplasm, more work is needed to uncover its cell of origin and true histogenesis.
  • [MeSH-minor] Biomarkers, Tumor / genetics. Female. Genetic Predisposition to Disease. Humans. Mutation. Treatment Outcome. beta Catenin / genetics

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  • (PMID = 19961258.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / beta Catenin
  • [Number-of-references] 30
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17. Keita M, Kampo MI, Timbo SK, Traoré CB, Diallo M, Doumbia-Singaré K, Ag Mohamed A: [Morbidity of the tumours of the sphere head and neck in Bamako]. Mali Med; 2009;24(3):1-6
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  • Among the 60 cases, 24 tumours (40%) were malign and 36 were benign.
  • Goiter was the most found benign tumor according to the results of the hystology analysis.

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  • (PMID = 20093222.001).
  • [ISSN] 1993-0836
  • [Journal-full-title] Le Mali médical
  • [ISO-abbreviation] Mali Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Mali
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18. Kim HY, Jung SN, Kwon H, Sohn WI, Moon SH: Angiomyoma in the buccal space. J Craniofac Surg; 2010 Sep;21(5):1634-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiomyoma is a rare benign tumor originated from vascular smooth muscle cells, in other words, the tunica media, and the characteristic is the detection of numerous blood vessels together with spindle-shape smooth muscle cells.

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  • (PMID = 20856064.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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19. Vercillo MS, Kim AW, Pitelka L, Gattuso P, Liptay MJ: Right middle lobectomy for a primary pulmonary leiomyoma: a case report. Cases J; 2009;2:8673
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  • INTRODUCTION: Primary leiomyoma of the lung is a rare benign tumor that usually presents as a solitary lesion predominantly in young females.
  • CONCLUSION: Primary pulmonary leiomyoma is a rare tumor distinct from benign metastasizing leiomyoma.

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  • [Cites] N Engl J Med. 1958 Jan 2;258(1):12-7 [13493727.001]
  • [Cites] Thorax. 1985 Apr;40(4):306-11 [4023981.001]
  • [Cites] Semin Thorac Cardiovasc Surg. 2003 Jul;15(3):310-4 [12973710.001]
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  • [Cites] J Thorac Cardiovasc Surg. 1978 Aug;76(2):257-61 [682658.001]
  • (PMID = 20184689.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827106
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20. Puizina-Ivić N, Sapunar D, Marasović D, Mirić L: An overview of Bcl-2 expression in histopathological variants of basal cell carcinoma, squamous cell carcinoma, actinic keratosis and seborrheic keratosis. Coll Antropol; 2008 Oct;32 Suppl 2:61-5
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  • In this study the authors have analyzed imunohistochemically the expression of Bcl-2 protein in the histopathological variants of the most common malignant tumors of the skin--basal cell carcinoma (BCC) and squamous cell tumor (SCC), as well as in the precancerous lesion actinic keratosis (AK) and in benign tumor seborrheic keratosis (SK).
  • Bcl-2 expression in solid, adenoid and cystic variants of BCC exhibited immunoreactivity of tumor stroma with more intense staining among peripheral palisading cells.
  • Among SCC in all samples, tumor tissue lack to express Bcl-2 positivity.
  • In clonal variant immunostaining was positive among cells in characteristic "nests" Distribution of Bcl-2 protein expression in solid, adenoid and cystic variant of BCC showed that peripheral proliferating cells are protected against apoptosis what permits tumor growth.
  • Bcl-2 expression supports the observation that tumor cells are derived from basal keratinocytes.
  • In SCC, lack of Bcl-2 expression indicates that origin of tumor cells is from more differentiated suprabasal keratinocytes.


21. Musani MA, Sohail Z, Zafar S, Malik S: Morphological pattern of parotid gland tumours. J Coll Physicians Surg Pak; 2008 May;18(5):274-7
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  • RESULTS: Out of 204 cases, 152 (74.5%) were benign and 52 (25.5%) were malignant.
  • Benign tumours were more common in females whereas malignant tumours were common in males.
  • The mean age of patients was 34 years and 42 years for benign and malignant tumours respectively.
  • Pleomorphic adenoma was most common benign tumor (83.5%), followed by Warthins tumour.
  • Superficial lobe of parotid gland was the commonest site, 120 benign and all 52 malignant tumours arising from it while 32 benign tumours originated from deep lobe.
  • Parotid swelling for years was main feature of benign tumours, whereas malignant tumours presented with pain, fixation to skin or underlying structure, cervical lymphadenopathy and facial palsy.
  • CONCLUSION: Pleomorphic adenoma was the most common benign tumour and mucoepidermoid carcinoma was most common malignant tumour.
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Fine-Needle. Child. Diagnosis, Differential. Disease Progression. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Morbidity / trends. Neoplasm Staging / methods. Pakistan / epidemiology. Retrospective Studies. Severity of Illness Index. Tomography, X-Ray Computed

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  • (PMID = 18541080.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Multicenter Study
  • [Publication-country] Pakistan
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22. Xue HD, Jin ZY, Liu W, Wang Y, Zhao WM: [Perfusion characteristics of normal pancreas and insulinoma on multi-slice spiral CT]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2006 Feb;28(1):68-70
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  • RESULTS: Benign insulinoma was pathologically confirmed in 12 out of the 21 subjects, while the remaining 9 subjects were normal.
  • In both normal and tumor-suffered subjects (n = 19), perfusion parameters of normal pancreatic parachyma were measured as follows: BF (p) = 104.
  • In subjects with insulinoma (n = 11), perfusion parameters of tumor tissue were measured as follows: F (i) = 206.5 +/- 42.2, BV (i) = 315.9 +/- 79.0, TFP (i) = 123.2 +/- 18.8, Permeability (i) = 102.5 +/- 54.
  • CONCLUSIONS: Benign insulinoma has perfusion characteristics of increased blood flow and blood volume, but its TTP is consistent with normal pancreas and has normal permeability.
  • MSCT allows further understanding of the blood flow of the normal pancreas and its benign tumor insulinoma.

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  • (PMID = 16548193.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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23. Rakototiana AF, Rakoto-Ratsimba HN, Rakotoarisoa AJ, Hunald FA, Breda Y: [Hemoperitoneum caused by traumatic rupture of mesenteric lymphangioma cyst. Case report from Madagascar]. Med Trop (Mars); 2008 Dec;68(6):645-6
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  • Mesenteric cystic lymphangioma is an uncommon benign tumor.
  • The patient who had a huge preexisting tumor mass presented with hemorrhagic shock symptoms following a severe fall.
  • Exploratory laparotomy revealed a large bleeding cyst-like mesenteric tumor.

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  • (PMID = 19639839.001).
  • [ISSN] 0025-682X
  • [Journal-full-title] Médecine tropicale : revue du Corps de santé colonial
  • [ISO-abbreviation] Med Trop (Mars)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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24. Ray WZ, Blackburn SL, Casavilca-Zambrano S, Barrionuevo C, Orrego JE, Heinicke H, Dowling JL, Perry A: Clinicopathologic features of recurrent dysembryoplastic neuroepithelial tumor and rare malignant transformation: a report of 5 cases and review of the literature. J Neurooncol; 2009 Sep;94(2):283-92
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  • [Title] Clinicopathologic features of recurrent dysembryoplastic neuroepithelial tumor and rare malignant transformation: a report of 5 cases and review of the literature.
  • Dysembryoplastic neuroepithelial tumors (DNETs) have traditionally been viewed as benign "quasihamartomatous" tumors widely considered curable with surgery alone.
  • Although the radiology was often alarming (e.g., new ring enhancing mass), the pathology remained benign in most cases.
  • These findings suggest that these patients may need closer follow-up than initially suggested, lending further support to the notion that this tumor behaves more like a benign neoplasm, rather than a dysplastic or hamartomatous lesion.
  • [MeSH-major] Brain Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Neoplasm Recurrence, Local / diagnosis. Neoplasms, Neuroepithelial / pathology


25. Riopel C, Michot C: [Chordomas]. Ann Pathol; 2007 Feb;27(1):6-15
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  • Chordoma is a rare bone tumor, believed to derive from notochordal rests, which generally arises at the two extremities of axial skeleton.
  • The recognition of new entities such as giant notochordal rest or hamartoma, and notochordal cells benign tumor, can lead to confusion since there is no consensus regarding their nature and whether or not they correspond to chordoma precursors.

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  • [CommentIn] Ann Pathol. 2007 Oct;27(5):389 [18185479.001]
  • (PMID = 17568354.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 53
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26. Casanova Espinosa A, Cisneros Serrano C, Girón Moreno RM, Olivera MJ, Moreno Balsalobre R, Zamora García E: [Pleural empyema associated with endobronchial lipoma]. Arch Bronconeumol; 2005 Mar;41(3):172-4
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  • Bronchial benign tumors comprise fewer than 4% of pulmonary neoplasms.
  • Endobronchial lipoma is an extremely rare benign neoplasm accounting for only 0.1% to 0.5% of all lung tumors.
  • Clinical symptoms of lipoma depend on the location of the tumor, the severity of bronchial obstruction, and the functional and anatomical effects on the parenchyma distal to the obstruction.
  • Computed axial tomography usually reveals the adipose composition of the lipomatous tumor.

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  • (PMID = 15766470.001).
  • [ISSN] 0300-2896
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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27. Revonta M, Raitanen J, Sihvo S, Koponen P, Klemetti R, Männistö S, Luoto R: Health and life style among infertile men and women. Sex Reprod Healthc; 2010 Aug;1(3):91-8
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  • Infertile women also had Chlamydia trachomatis infection, benign tumor in their uterus and intestinal disease more often than fertile women.

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  • [Copyright] Copyright © 2010 Elsevier B.V. All rights reserved.
  • (PMID = 21122604.001).
  • [ISSN] 1877-5764
  • [Journal-full-title] Sexual & reproductive healthcare : official journal of the Swedish Association of Midwives
  • [ISO-abbreviation] Sex Reprod Healthc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Dietary Fats; 0 / Fatty Acids
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28. Tsunezuka Y, Shimizu Y, Tanaka N, Takayanagi T, Kawano M: Positron emission tomography in relation to Noguchi's classification for diagnosis of peripheral non-small-cell lung cancer 2 cm or less in size. World J Surg; 2007 Feb;31(2):314-7
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  • RESULTS: Eighty-three patients had malignant lesions, and 67 patients had benign lesions.
  • CONCLUSION: The accuracy of( 18)F-FDG-PET is generally low in distinguishing malignancy from benign lesions in small lesions (<2.0-cm diameter).
  • The significance of PET as a diagnostic tool is small, especially when the tumor has a ground-glass component at a high rate.
  • The sensitivity of PET is high in small invasive carcinomas without a BAC component, but it is difficult to distinguish carcinoma from benign tumor from its image.
  • [MeSH-major] Adenocarcinoma, Bronchiolo-Alveolar / diagnostic imaging. Carcinoma, Non-Small-Cell Lung / diagnostic imaging. Fluorodeoxyglucose F18. Lung Neoplasms / diagnostic imaging. Mixed Tumor, Malignant / diagnostic imaging. Positron-Emission Tomography. Radiopharmaceuticals

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  • [Cites] J Thorac Cardiovasc Surg. 2002 Aug;124(2):278-84 [12167787.001]
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  • (PMID = 17219276.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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29. Cornette J, Festen S, van den Hoonaard TL, Steegers EA: Mesenchymal hamartoma of the liver: a benign tumor with deceptive prognosis in the perinatal period. Case report and review of the literature. Fetal Diagn Ther; 2009;25(2):196-202
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  • [Title] Mesenchymal hamartoma of the liver: a benign tumor with deceptive prognosis in the perinatal period. Case report and review of the literature.
  • Hepatic mesenchymal hamartoma are rare benign tumors.
  • [MeSH-minor] Adult. Female. Humans. Infant, Newborn. Pregnancy. Prognosis

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  • [Copyright] Copyright (c) 2009 S. Karger AG, Basel.
  • (PMID = 19365132.001).
  • [ISSN] 1421-9964
  • [Journal-full-title] Fetal diagnosis and therapy
  • [ISO-abbreviation] Fetal. Diagn. Ther.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 36
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30. Gupta R, Khurana N, Singh DK, Singh S: Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm. Indian J Pathol Microbiol; 2008 Jul-Sep;51(3):447-8
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  • [Title] Schwannoma of nasal cavity with intracranial extension: a rare but interesting phenomenon in a benign neoplasm.

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  • (PMID = 18723990.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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31. Fukui S, Torimoto K, Nakai Y, Kagebayashi Y, Samma S, Shimada K: [Leiomyoma of the spermatic cord: a case report]. Hinyokika Kiyo; 2009 Apr;55(4):237-9
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  • The patient received a 12-month course of watching without medication, because these findings suggested the mass was a benign tumor.
  • However, the tumor gradually increased in size to 50 mm in diameter during the period.
  • The tumor probably arose from the smooth muscle of the vessel in the spermatic cord.

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  • (PMID = 19462832.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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32. Al-Otaibi M, Lach B, Al Shail E: December 2004: one-year-old girl with aggressive skull tumor. Brain Pathol; 2005 Apr;15(2):171-3
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  • [Title] December 2004: one-year-old girl with aggressive skull tumor.
  • December 2004. Twelve-month old girl presented with recurrent subcutaneous lesion in the left parietal region, one year after excision of a "benign" tumor.
  • An MRI demonstrated left temporo-parietal skull tumor infiltrating the soft tissue, surrounding craniotomy flap, and extending to the brain parenchyma.
  • Biopsy revealed biphasic neoplasm displaying nests of poorly differentiated neuroblastic cells positive for synaptophysin and pigmented cuboidal epithelioid cell positive for keratins, epithelial membrane antigen and MHB-45.
  • Interestingly, cell with the neuroblastic immunophenotype displayed 80% nuclear MIB-1 reactivity indicating that the aggressiveness of the neoplasm was confined mostly to this pattern of differentiation.
  • The overall histological features are consistent with a rare malignant variant of a melanotic neuroectodermal tumor of infancy.
  • [MeSH-major] Neoplasm Recurrence, Local / pathology. Neuroectodermal Tumor, Melanotic / pathology. Parietal Bone / pathology. Skull Neoplasms / pathology

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  • (PMID = 15912891.001).
  • [ISSN] 1015-6305
  • [Journal-full-title] Brain pathology (Zurich, Switzerland)
  • [ISO-abbreviation] Brain Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Switzerland
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33. Wadasadawala T, Trivedi S, Gupta T, Epari S, Jalali R: The diagnostic dilemma of primary central nervous system melanoma. J Clin Neurosci; 2010 Aug;17(8):1014-1017
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  • The CNS can be affected by a spectrum of melanocytic lesions ranging from diffuse neurocutaneous melanosis, to a focal and benign neoplasm (melanocytoma), and to an overtly malignant tumor (melanoma).

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  • (PMID = 20627582.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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34. Kruck S, Bedke J, Hennenlotter J, Ohneseit PA, Kuehs U, Senger E, Sievert KD, Stenzl A: Activation of mTOR in renal cell carcinoma is due to increased phosphorylation rather than protein overexpression. Oncol Rep; 2010 Jan;23(1):159-63
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  • Tissue microarray immunohistochemistry and Western blot analysis of tumor and benign tissue from 10 patients subjected to tumor nephrectomy were investigated.
  • Ratios of tumor versus benign tissue were calculated and compared by the Wilcoxon/Kruskal-Wallis test.
  • Immunohistochemical expressions of mTOR and p-mTOR were 49 and 40% in benign renal parenchyma, whereas it was 20 and 42% in tumor tissue.
  • Ratios of tumor versus benign tissue revealed a reduction to 0.44 for mTOR and corresponding elevation to 1.29 for p-mTOR (p<0.05).
  • The rate of p-mTOR to mTOR was 1.19 in benign, whereas it was 5.30 in tumor tissue.
  • Western blot densitometry detected lower expressions of mTOR in tumor compared to benign tissues.
  • Ratio of p-mTOR to mTOR were significantly different in benign versus tumor tissue (0.86 vs. 1.37; p<0.04).
  • The observation that RCC specimens exhibit higher levels of p-mTOR in RCC compared to benign renal parenchyma indicate the role of mTOR phosphorylation in RCC tumor development and progression.

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  • (PMID = 19956876.001).
  • [ISSN] 1791-2431
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Intracellular Signaling Peptides and Proteins; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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35. Downs LS Jr, Lima PH, Bliss RL, Blomquist CH: Cathepsins B and D activity and activity ratios in normal ovaries, benign ovarian neoplasms, and epithelial ovarian cancer. J Soc Gynecol Investig; 2005 Oct;12(7):539-44
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  • [Title] Cathepsins B and D activity and activity ratios in normal ovaries, benign ovarian neoplasms, and epithelial ovarian cancer.
  • OBJECTIVE: Cathepsins B (CB) and D (CD) belong to a family of proteases felt to be important in tumor metastasis and invasion.
  • Tissue specimens were divided into four groups: normal ovary, benign neoplasm, early-stage (I/II) cancer, and late-stage (III/IV) cancer.
  • CONCLUSIONS: CB activity is associated with invasive ovarian neoplasm.
  • [MeSH-minor] Female. Humans. Isoenzymes. Tumor Cells, Cultured

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  • (PMID = 16202931.001).
  • [ISSN] 1556-7117
  • [Journal-full-title] Journal of the Society for Gynecologic Investigation
  • [ISO-abbreviation] J. Soc. Gynecol. Investig.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Isoenzymes; EC 3.4.22.1 / Cathepsin B; EC 3.4.23.5 / Cathepsin D
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36. Leung TK, Lee CM, Shen LK, Chen YY: Differential diagnosis of cystic lymphangioma of the pancreas based on imaging features. J Formos Med Assoc; 2006 Jun;105(6):512-7
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  • Lymphangioma is a benign tumor, which is a consequence of lymphatic malformation with blockage of lymphatic flow.

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  • (PMID = 16801041.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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37. Tak WY, Park SY, Jeon SW, Cho CM, Kweon YO, Kim SK, Choi YH, Chung JM: Ultrasonography-guided percutaneous radiofrequency ablation for treatment of a huge symptomatic hepatic cavernous hemangioma. J Clin Gastroenterol; 2006 Feb;40(2):167-70
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  • Hepatic cavernous hemangioma is the most common benign tumor of the liver.
  • Appropriate management of this tumor remains a controversial topic.

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  • (PMID = 16394880.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Bertalanffy A, Roessler K, Koperek O, Gelpi E, Prayer D, Knosp E: Recurrent central neurocytomas. Cancer; 2005 Jul 1;104(1):135-42
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  • BACKGROUND: Since the first description of Central neurocytomas (CNs) as a benign tumor entity in 1982, there has been great enthusiasm regarding the benign course and the curative surgical approach to this disease.
  • The MIB-1 proliferation index ranged from 0.8-11% (median of 4.6%), but was reported to be 46.8% in the malignant transformed tumor.
  • [MeSH-major] Brain Neoplasms / epidemiology. Neoplasm Recurrence, Local / epidemiology. Neurocytoma / epidemiology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Female. Follow-Up Studies. Humans. Male. Retrospective Studies. Time Factors

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  • (PMID = 15880432.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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39. Jun F, Li L, Ning L, Yan L, Siquan T, Shixi L: Giant laryngeal angioleiomyomas: a case report with review of literature. Am J Otolaryngol; 2009 May-Jun;30(3):219-20
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  • We report a recently encountered case of vascular leiomyoma in the larynx, a benign tumor that is rare in the organ, in a 52-year-old man.
  • Histologic study showed smooth muscle cell proliferation, especially surrounded by an abundance of blood vessels, and the tumor was diagnosed as a vascular leiomyoma.
  • Tracheotomy was required in this case depending on the occurrence site if the tumor and its size.

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  • (PMID = 19410131.001).
  • [ISSN] 1532-818X
  • [Journal-full-title] American journal of otolaryngology
  • [ISO-abbreviation] Am J Otolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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40. Cosenza UM, Galati G, Zofrea P, Maggi S, Marasco A, Castelli M, Masoni L, Brescia A: Clinical and biological features of an intranodal palisaded myofibroblastoma. Anticancer Res; 2006 May-Jun;26(3B):2349-52
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  • Intranodal palisaded myofibroblastoma (IPM) is a rare benign tumor of the lymph nodes probably arising from smooth muscle-like cells.
  • The tumor is characterized by intranodal proliferation of spindle cells.
  • We report a novel case of IPM that confirms the myofibroblastic differentiation of the tumor.

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  • (PMID = 16821615.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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41. Tweezer-Zaks N, Marai I, Livneh A, Bank I, Langevitz P: Autoimmune phenomena following prostatectomy. Isr Med Assoc J; 2005 Sep;7(9):575-7
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  • BACKGROUND: Benign prostatic hypertrophy is the most common benign tumor in males, resulting in prostatectomy in 20-30% of men who live to the age of 80.


42. Piert M, Park H, Khan A, Siddiqui J, Hussain H, Chenevert T, Wood D, Johnson T, Shah RB, Meyer C: Detection of aggressive primary prostate cancer with 11C-choline PET/CT using multimodality fusion techniques. J Nucl Med; 2009 Oct;50(10):1585-93
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  • Volumes of interest from tumor and benign tissue were defined on the basis of histology and were transferred into coregistered (11)C-choline PET/CT volumes to calculate the mean (T((mean))/B) and maximum (T((max))/B) ratio of tumor to benign prostate background.
  • On the basis of MIB-1/Ki-67 expression in tumor tissues represented on a tissue microarray, we assessed whether (11)C-choline uptake correlated with local Gleason score and tumor proliferation.
  • RESULTS: Histology confirmed 42 tumor nodules with Gleason scores between 3 + 2 and 4 + 4, with volumes ranging from 0.03 to 12.6 cm(3).
  • CONCLUSION: On the basis of our preliminary data using ratios of tumor to benign prostate background, (11)C-choline preferentially identified aggressive primary prostate cancer.
  • [MeSH-minor] Aged. Algorithms. Biomarkers, Tumor / metabolism. Carbon Radioisotopes / chemistry. Gene Expression Regulation, Neoplastic. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Prostatectomy

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  • (PMID = 19759109.001).
  • [ISSN] 1535-5667
  • [Journal-full-title] Journal of nuclear medicine : official publication, Society of Nuclear Medicine
  • [ISO-abbreviation] J. Nucl. Med.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P50 CA069568; United States / NCI NIH HHS / CA / P50 CA069568; United States / NCI NIH HHS / CA / P50 CA069568-10
  • [Publication-type] Clinical Trial; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carbon Radioisotopes; N91BDP6H0X / Choline
  • [Other-IDs] NLM/ NIHMS170399; NLM/ PMC2837847
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43. Matsubayashi S, Nakashima M, Kumagai K, Egashira M, Naruke Y, Kondo H, Hayashi T, Shindo H: Immunohistochemical analyses of beta-catenin and cyclin D1 expression in giant cell tumor of bone (GCTB): a possible role of Wnt pathway in GCTB tumorigenesis. Pathol Res Pract; 2009;205(9):626-33
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  • [Title] Immunohistochemical analyses of beta-catenin and cyclin D1 expression in giant cell tumor of bone (GCTB): a possible role of Wnt pathway in GCTB tumorigenesis.
  • Giant cell tumor of bone (GCTB) is a benign neoplasm but occasionally shows local recurrence, and histologically consists of osteoclast-like giant cells (GC) and stromal mononuclear cells (SC), which are capable of proliferation and osteoblastic differentiation.
  • Importantly, it was suggested that the nuclear beta-catenin staining level might be associated with tumor recurrence in GCTB.
  • [MeSH-major] Bone Neoplasms / metabolism. Cyclin D1 / biosynthesis. Giant Cell Tumor of Bone / metabolism. Wnt Proteins / metabolism. beta Catenin / biosynthesis
  • [MeSH-minor] Adolescent. Adult. Cell Nucleus / metabolism. Female. Gene Expression. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Ki-67 Antigen / biosynthesis. Ki-67 Antigen / genetics. Male. Middle Aged. Neoplasm Recurrence, Local / metabolism. Signal Transduction / physiology. Young Adult

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  • (PMID = 19324500.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Wnt Proteins; 0 / beta Catenin; 136601-57-5 / Cyclin D1
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44. Qi F, Zhang X, Zhang Y, Wang E: [Significance of p53 protein expression and p53 gene mutation in so-called pulmonary sclerosing hemangioma]. Zhongguo Fei Ai Za Zhi; 2006 Apr 20;9(2):147-51
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  • BACKGROUND: So-called pulmonary sclerosing hemangioma (PSH) is an uncommon tumor of the lung and its histogenesis and origin are uncertain to date.
  • A general consensus appears to have been reached that PSH is a benign neoplasm, but a few PSHs are found to invade and metastasize.
  • The expression of p53 protein and mutation of p53 gene are significant parameters which can reflect biological behavior of tumor cells.

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  • (PMID = 21144300.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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45. Torrijos-Aguilar A, Alegre-de Miquel V, Pitarch-Bort G, Mercader-García P, Fortea-Baixauli JM: [Cutaneous granular cell tumor: a clinical and pathologic analysis of 34 cases]. Actas Dermosifiliogr; 2009 Mar;100(2):126-32
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  • [Title] [Cutaneous granular cell tumor: a clinical and pathologic analysis of 34 cases].
  • [Transliterated title] Tumor de células granulares cutáneo: análisis clínico-patológico de treinta y cuatro casos.
  • BACKGROUND: Granular cell tumor (GCT), also known as Abrikossoff tumor, is an uncommon benign neoplasm, probably of neural origin derived from Schwann cells.
  • OBJECTIVES: We aimed to analyze the clinical, histologic, and immunohistochemical characteristics associated with this tumor and to determine whether these findings correspond to those reported to date in the literature.
  • CONCLUSIONS: Our series confirms the characteristics described previously for GCT, except for certain peculiarities, and supports the presence of pustulo-ovoid bodies as an additional histologic finding for diagnosis of this tumor.
  • [MeSH-major] Granular Cell Tumor / epidemiology. Mouth Neoplasms / epidemiology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor. Child. Child, Preschool. Cytoplasmic Granules / ultrastructure. Diagnosis, Differential. Female. Fibroma / diagnosis. Humans. Male. Middle Aged. Retrospective Studies. Skin Neoplasms / chemistry. Skin Neoplasms / diagnosis. Skin Neoplasms / epidemiology. Skin Neoplasms / pathology. Staining and Labeling. Young Adult

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  • (PMID = 19445877.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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46. de Ipolyi AR, Yang I, Buckley A, Barbaro NM, Cheung SW, Parsa AT: Fluctuating response of a cystic vestibular schwannoma to radiosurgery: case report. Neurosurgery; 2008 May;62(5):E1164-5; discussion E1165
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  • OBJECTIVE: A vestibular schwannoma (VS) is a benign tumor of the VIIIth cranial nerve that can often be treated by microsurgery or radiosurgery and demonstrates high tumor control rates.
  • INTERVENTION: After GKS with a 12-Gy dose to the 50% isodose line, the tumor expanded transiently to 3.2 cm and then regressed to 1.0 cm over the next 2 years.
  • After microsurgical tumor excision, the patient's symptoms abated.
  • The mechanisms responsible for radiation-induced cystic tumor expansion have not been thoroughly elucidated.
  • The risk of unpredictable tumor enlargement should be discussed with patients when considering GKS for cystic tumors.
  • [MeSH-major] Neoplasm Recurrence, Local / surgery. Neuroma, Acoustic / pathology. Neuroma, Acoustic / surgery. Radiosurgery

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  • (PMID = 18580785.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Jordan SJ, Green AC, Whiteman DC, Webb PM, Australian Ovarian Cancer Study Group: Risk factors for benign, borderline and invasive mucinous ovarian tumors: epidemiological evidence of a neoplastic continuum? Gynecol Oncol; 2007 Nov;107(2):223-30
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  • [Title] Risk factors for benign, borderline and invasive mucinous ovarian tumors: epidemiological evidence of a neoplastic continuum?
  • OBJECTIVE: Some molecular and histological evidence suggests that mucinous epithelial ovarian cancers develop via a sequence from benign tumor through borderline tumor to invasive cancer.
  • Such a sequence would predict some shared risk factors between the different tumor types.
  • To investigate this, we examined risk factors for benign, borderline and invasive mucinous ovarian tumors.
  • Women with benign (n=133), borderline (n=147) and invasive (n=43) mucinous tumors of the ovary and women from the general population (n=1487) completed comprehensive health and lifestyle questionnaires.
  • RESULTS: Although parity was inversely related to risk of benign, borderline and invasive tumors, increasing numbers of births did not further decrease risk of any of the tumor types.
  • However, 20 or more pack-years of smoking was associated with a more than twofold increase in risk of all three tumor types (OR=2.7, 95% CI 1.6-4.4 for benign tumors; OR=2.7, 95% CI 1.7-4.4 for borderline tumors; and OR=2.1, 95% CI 0.9-5.0 for invasive cancers) compared to never smoking.
  • Furthermore, patterns of risk factors across benign, borderline and invasive mucinous ovarian tumors are generally consistent with an adenoma-to-carcinoma sequence as the developmental pathway for this subtype of ovarian cancer.
  • [MeSH-minor] Adult. Aged. Australia. Case-Control Studies. Cell Transformation, Neoplastic / pathology. Female. Health Status. Humans. Life Style. Middle Aged. Neoplasm Invasiveness. Odds Ratio. Reproductive History. Risk Assessment. Risk Factors. Smoking / adverse effects. Surveys and Questionnaires

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  • (PMID = 17662378.001).
  • [ISSN] 1095-6859
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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48. Roussel A, Thomassin-Naggara I, Darai E, Marsault C, Bazot M: [Value of diffusion-weighted imaging in the evaluation of adnexal tumors]. J Radiol; 2009 May;90(5 Pt 1):589-96
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  • PURPOSE: To determine the value of diffusion-weighted imaging (DWI) in the evaluation of adnexal tumors, especially to distinguish between malignant and benign tumors.
  • Fifty-four patients with pelvic tumors (32 malignant and 22 benign) were referred for MRI of the pelvis.
  • The signal of solid and cystic tumor components was evaluated on T2W and b=1000 DWI, and ADC values were obtained.
  • RESULTS: T2W hypointensity or absence of hyperintense signal on b=1000 DWI sequences was suggestive of a benign tumor.
  • ADC values did not appear to discriminate between malignant and benign tumors.
  • Also, the signal intensity of cystic tumor components on DWI sequences was not helpful to distinguish between malignant and benign tumor.
  • CONCLUSION: The evaluation of solid tumor components on DWI appears to be helpful for adnexal tumor characterization.

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  • (PMID = 19503047.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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49. Hsu CC, Chen DJ, Chen HC: Lipofibromatous hamartoma of the median nerve with long-term follow-up. Chang Gung Med J; 2005 Feb;28(2):111-6
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  • Lipofibromatous hamartoma is a rare, benign tumor that most often involves the median nerve.
  • Although there were no symptoms or signs of carpal tunnel compression, the growth of the tumor was progressing.
  • Treatment of this benign tumor is still controversial.

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  • (PMID = 15880987.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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50. Grabowski L, Kołodziejczyk A, Burzej-Uchto M: [A case of giant pleomorphic adenoma of the parotid gland]. Otolaryngol Pol; 2008;62(2):195-8
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  • Pleomorphic adenoma is the most common benign tumor of the major salivary glands.
  • A review of the literature confirms that this kind of tumor is less common in the minor salivary glands.
  • MATERIAL AND METHOD: We encountered such a tumor in a 55-year-old woman who was admitted to our Hospital.
  • RESULTS: The tumor was located under the right side of the face and was removed surgically.
  • CONCLUSION: Pleomorphic adenoma is the most common benign tumor of the major salivary glands.

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  • (PMID = 18637446.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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51. Tchente Nguefack C, Fogaing AD, Tejiokem MC, Nana Njotang P, Mbu R, Leke R: [Pregnancy outcome in a group of Cameroonian women with uterine fibroids]. J Gynecol Obstet Biol Reprod (Paris); 2009 Oct;38(6):493-9
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  • [Title] [Pregnancy outcome in a group of Cameroonian women with uterine fibroids].
  • [Transliterated title] Evolution de la grossesse sur un utérus fibromyomateux chez un groupe de femmes camerounaises.
  • INTRODUCTION: Uterine fibroids are the most common benign tumor seen in women at reproductive age.
  • The association of pregnancy and uterine fibroids is about 0.5 to 4%.
  • The main objective was to compare the incidence of complications of pregnancy and delivery in two groups of women: group 1 (women with uterine fibroids) and group 2 (women without fibroids).
  • CONCLUSION: We concluded that pregnancy in women with uterine fibroids is a high-risk pregnancy and needs a particular follow-up.
  • [MeSH-minor] Abortion, Threatened / epidemiology. Adult. Cameroon. Case-Control Studies. Cesarean Section / statistics & numerical data. Drug Utilization / statistics & numerical data. Female. Humans. Pregnancy. Premature Birth / epidemiology. Prospective Studies. Tocolytic Agents / therapeutic use

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  • (PMID = 19576703.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Tocolytic Agents
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52. Spielmann PM, Adamson R, Cheng K, Sanderson RJ: Juvenile nasopharyngeal angiofibroma: spontaneous resolution. Ear Nose Throat J; 2008 Sep;87(9):521-3
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  • Juvenile nasopharyngeal angiofibroma is a rare, benign tumor that occurs most often in adolescent males.
  • Common practice is to excise the tumor with open or endoscopic surgery.
  • [MeSH-minor] Adolescent. Biopsy, Needle. Humans. Immunohistochemistry. Magnetic Resonance Imaging / methods. Male. Nasal Obstruction / diagnosis. Nasal Obstruction / etiology. Neoplasm Staging. Remission, Spontaneous. Risk Assessment. Tomography, X-Ray Computed / methods

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  • (PMID = 18800325.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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53. Kajiwara H, Osamura Y: [Trends in gastroenteropancreatic neuroendocrine tumors]. Nihon Geka Gakkai Zasshi; 2008 May;109(3):123-7
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  • In addition, carcinoids were originally thought to be variants of a benign tumor type with a low malignancy rate, but thereafter metastases were observed.
  • [MeSH-minor] Antineoplastic Agents, Hormonal / therapeutic use. Digestive System Surgical Procedures. Humans. Neoplasm Staging. Octreotide / therapeutic use. Receptors, Somatostatin. World Health Organization

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  • (PMID = 18536314.001).
  • [ISSN] 0301-4894
  • [Journal-full-title] Nihon Geka Gakkai zasshi
  • [ISO-abbreviation] Nihon Geka Gakkai Zasshi
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal; 0 / Receptors, Somatostatin; RWM8CCW8GP / Octreotide
  • [Number-of-references] 12
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54. Kato T, Takano M, Mizoguchi K, Ikeda R, Nakamura T, Akakura K, Hikage T, Inoue T: A case of fibrous pseudotumor originating from tunica vaginalis testis. Hinyokika Kiyo; 2005 Jul;51(7):483-6
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  • Based on the preoperative diagnosis of scrotal or spermatic cordal benign tumor, local excision was performed.
  • Fibrous pseudotumor is a benign fibroproliferative lesion with dense hyalinization and sometimes focal calcification.
  • Our case was of a benign pseudotumor and orchiectomy could have been avoided.

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  • (PMID = 16119816.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 6
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55. Uke MS, Kulkarni MB, Ajit D, Gujral S: Diagnosis of hidradenoma papilliferum of the vulva on cytologic smears: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):907-10
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  • BACKGROUND: Hidradenoma papilliferum is a rare benign tumor of the vulva that occurs mainly in women in the skin of the anogenital region.
  • Clinically it may mimic a carcinoma, so the correct cytologic interpretation of the tumor cells with subsequent careful histologic confirmation is essential for good management.
  • Fine needle aspiration cytology and vulvar scraping of the lesion were reported as a malignant tumor, and the case was referred to our center for further management.
  • Repeat vulvar smears showed mainly groups and clusters of benign-looking glandular cells and were interpreted as a benign tumor.
  • The clinical presentation should not mislead the cytologic interpretation of the tumor cells.

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  • (PMID = 21053567.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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56. Ip YT, Yuan JQ, Cheung H, Chan JK: Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor? Am J Surg Pathol; 2010 Nov;34(11):1695-700
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  • [Title] Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor?
  • Hemangioblastoma is a benign tumor that can occur sporadically, or in association with von Hippel-Lindau disease in approximately one-quarter of the cases.
  • Many of the tumor cells showed pleomorphic nuclei, but the mitotic figures were rare.
  • This benign neoplasm which can be mistaken for various malignancies such as renal cell carcinoma, epithelioid angiomyolipoma, adrenal cortical carcinoma, and paraganglioma, deserves wider recognition for its occurrence as a primary renal tumor.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. Hematuria / etiology. Humans. Immunohistochemistry. Inhibins / analysis. Keratins / analysis. Low Back Pain / etiology. Male. Middle Aged. Nephrectomy. Phosphopyruvate Hydratase / analysis. Polycythemia / etiology. S100 Proteins / analysis

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  • [CommentIn] Am J Surg Pathol. 2011 Apr;35(4):623-4 [21378542.001]
  • (PMID = 20924277.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / inhibin-alpha subunit; 57285-09-3 / Inhibins; 68238-35-7 / Keratins; EC 4.2.1.11 / Phosphopyruvate Hydratase
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57. Fu K, Meng ZB, Li J, Li HC: [Repairing the defect of benign bone tumor with the coralline hydroxyapatite]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2008 May;33(5):421-4
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  • [Title] [Repairing the defect of benign bone tumor with the coralline hydroxyapatite].
  • OBJECTIVE: To observe the clinical effect of repairing bone defectin post-operation benign tumor with coralline hydroxyapatite(CHAP).
  • The CHAP was implanted into the lesion after bone tumor curettage to 25 patients.
  • [MeSH-major] Bone Neoplasms / surgery. Ceramics. Giant Cell Tumor of Bone / surgery. Hydroxyapatites. Prostheses and Implants

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  • (PMID = 18544846.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Bone Substitutes; 0 / Hydroxyapatites; 0 / coralline hydroxyapatite
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58. Zacharakis E, Freilich S, Rekhraj S, Athanasiou T, Paraskeva P, Ziprin P, Darzi A: Transanal endoscopic microsurgery for rectal tumors: the St. Mary's experience. Am J Surg; 2007 Nov;194(5):694-8
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  • During the follow-up, benign tumor recurrence was detected in 3 patients (6.3%).
  • COMMENTS: Transanal endoscopic microsurgery is a safe and feasible technique with low incomplete excision rates and may be the preferred method in patients with benign rectal tumors.

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  • (PMID = 17936438.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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59. Gardini A, Dubini A, Saragoni L, Padovani F, Garcea D: [Benign solitary fibrous tumor of the pancreas: a rare location of extra-pleural fibrous tumor. Single case report and review of the literature]. Pathologica; 2007 Feb;99(1):15-8
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  • [Title] [Benign solitary fibrous tumor of the pancreas: a rare location of extra-pleural fibrous tumor. Single case report and review of the literature].
  • [Transliterated title] Tumore fibroso benigno solitario del pancreas: una rara localizzazione di tumore fibroso extrapleurico. Caso clinico e revisione della letteratura.
  • In this report we describe the case of a patient with a single primary solitary fibrous tumor of the pancreatic head with a review of the literature.
  • CONCLUSIONS: Extra pleural solitary fibrous tumor are often benign lesions.

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  • (PMID = 17566307.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 22
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60. Yu DK, Joo YH, Cho KH: Trichoblastoma with apocrine and sebaceous differentiation. Am J Dermatopathol; 2005 Feb;27(1):6-8
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  • Trichoblastoma is a rare, benign tumor that differentiates toward the hair germ, the embryonic precursor of a hair follicle.
  • An immunohistochemical study showed that the neoplasm, or areas in it, stained positive for low molecular cytokeratin, high molecular cytokeratin, EMA, S-100, and GCDFP-15.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Cell Transformation, Neoplastic. Female. Humans. Immunohistochemistry. Middle Aged. Treatment Outcome

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  • (PMID = 15677969.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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61. Zhang B, Zhang J, Xu ZY, Xie HL: Expression of RECK and matrix metalloproteinase-2 in ameloblastoma. BMC Cancer; 2009;9:427
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  • BACKGROUND: Ameloblastoma is a frequent odontogenic benign tumor characterized by local invasiveness, high risk of recurrence and occasional metastasis and malignant transformation.
  • Matrix metalloproteinase-2 (MMP-2) promotes tumor invasion and progression by destroying the extracellular matrix (ECM) and basement membrane.
  • METHODS: Immunohistochemistry and reverse transcription-polymerase chain reaction (RT-PCR) were employed to detect the protein and mRNA expression of RECK and MMP-2 in keratocystic odontogenic tumor (KCOT), ameloblastoma and ameloblastic carcinoma.

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  • (PMID = 19995435.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / RECK protein, human; 0 / RNA, Messenger; EC 3.4.24.24 / Matrix Metalloproteinase 2
  • [Other-IDs] NLM/ PMC2794878
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62. Jung HS, Choi SH, Noh JH, Ohi SH, Ahn YR, Lee MK, Kim KW: Healthy twin birth after autologous islet transplantation in a pancreatectomized patient due to a benign tumor. Transplant Proc; 2007 Jun;39(5):1723-5
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  • [Title] Healthy twin birth after autologous islet transplantation in a pancreatectomized patient due to a benign tumor.
  • PATIENT: A 35-year-old woman who underwent distal pancreatectomy owing to a solid pseudopapillary neoplasm received an autologous islet transplantation (140,000 islet equivalents).
  • RESULTS: The patient showed impaired glucose tolerance before pancreatectomy, but improved to a normal glucose tolerance after transplantation, maintaining euglycemia until pregnancy.
  • Because her fasting glucose levels were within the normal range during pregnancy, fasting insulin represented insulin resistance.
  • Her fasting insulin levels abruptly increased in the third trimester of pregnancy, but returned after delivery.
  • During pregnancy, it increased again, but could not compensate for the insulin resistance.
  • CONCLUSIONS: The current report suggested a successful pregnancy after autologous islet transplantation that did not itself permanently deteriorate graft function.
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Humans. Infant. Infant, Newborn. Pregnancy. Pregnancy Outcome. Transplantation, Autologous


63. Carrieri G, Corvasce T, Annese P, Tolve I, Caniglia A, Di Sabato G: Endoscopic treatment of a large leiomyoma of the bladder. Arch Ital Urol Androl; 2005 Jun;77(2):111-2
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  • Leiomyoma is a benign neoplasm rarely found in the bladder.

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  • (PMID = 16146274.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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64. Schlottmann K: [Reader's letter concerning the article by H. Strunk et al. (Fortschr Röntgenstr 2005, 177:900-904). Erroneous diagnosis of liver metastasis as benign tumor in the contrast media aided "Low-MI-Real-Time" sonography with SonoVue]. Rofo; 2005 Dec;177(12):1722-3; author reply 1723
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  • [Title] [Reader's letter concerning the article by H. Strunk et al. (Fortschr Röntgenstr 2005, 177:900-904). Erroneous diagnosis of liver metastasis as benign tumor in the contrast media aided "Low-MI-Real-Time" sonography with SonoVue].
  • [Transliterated title] Leserbrief zum Beitrag H. Strunk et al. (Fortschr Röntgenstr 2005; 177: 900-904). Fehldiagnose einer Lebermetastase als benigner Tumor in der kontrastmittelgestützten "Low-MI-Real-Time"--Sonographie mit SonoVue.

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  • [CommentOn] Rofo. 2005 Jun;177(6):900-2 [15902642.001]
  • (PMID = 16382508.001).
  • [ISSN] 1438-9029
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] Comment; Letter
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Phospholipids; 0 / contrast agent BR1; WS7LR3I1D6 / Sulfur Hexafluoride
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65. Bignami M, Pistochini A, Meloni F, Delehaye E, Castelnuovo P: A rare case of oncocytic Schneiderian papilloma with intradural and intraorbital extension with notes of operative techniques. Rhinology; 2009 Sep;47(3):316-9
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  • Epithelial cells of cylindrical cell papilloma are oncocytes, which arise from the sinonasal respiratory epithelium, hence the term Oncocytic Schneiderian papilloma.This is a rare and benign neoplasm of the nose and paranasal sinuses and it should be considered in the work-up of all unilateral nasal polypoid lesions.

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  • (PMID = 19839258.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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66. Abrahão AC, Camisasca DR, Bonelli BR, Cabral MG, Lourenço SQ, Torres SR, Pinto DS Jr: Recurrent bilateral gingival peripheral calcifying epithelial odontogenic tumor (Pindborg tumor): a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 Sep;108(3):e66-71
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  • [Title] Recurrent bilateral gingival peripheral calcifying epithelial odontogenic tumor (Pindborg tumor): a case report.
  • Calcifying epithelial odontogenic tumor (CEOT) is an extremely rare, benign neoplasm, accounting for approximately 1% of all odontogenic tumors.
  • Morphologic features, and histochemical and immunohistochemical tests revealed bilateral peripheral calcifying odontogenic epithelial tumor.
  • [MeSH-major] Gingival Neoplasms / diagnosis. Neoplasm Recurrence, Local / diagnosis. Odontogenic Tumors / diagnosis

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  • (PMID = 19716494.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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67. Kim BH, Henderson BA: Intraocular choristoma. Semin Ophthalmol; 2005 Oct-Dec;20(4):223-9
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  • Although it is regarded as a benign tumor, it grows progressively and can decrease visual function.

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  • (PMID = 16352493.001).
  • [ISSN] 0882-0538
  • [Journal-full-title] Seminars in ophthalmology
  • [ISO-abbreviation] Semin Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 54
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68. Welborn J, Fenner S, Parks R: Angioleiomyoma: a benign tumor with karyotypic aberrations. Cancer Genet Cytogenet; 2010 Jun;199(2):147-8
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  • [Title] Angioleiomyoma: a benign tumor with karyotypic aberrations.

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  • (PMID = 20471520.001).
  • [ISSN] 1873-4456
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
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69. Comtesse N, Zippel A, Walle S, Monz D, Backes C, Fischer U, Mayer J, Ludwig N, Hildebrandt A, Keller A, Steudel WI, Lenhof HP, Meese E: Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets. Proc Natl Acad Sci U S A; 2005 Jul 5;102(27):9601-6
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  • [Title] Complex humoral immune response against a benign tumor: frequent antibody response against specific antigens as diagnostic targets.
  • This study was aimed to address the complexity and specificity of humoral immune response against a benign human tumor.
  • We detected 17 antigens exclusively with patient sera, including 12 sera that were reactive against KIAA1344, 9 against natural killer tumor recognition (NKTR), and 7 against SRY (sex determining region Y)-box2 (SOX2).
  • Our results show a highly complex but specific humoral immune response against a benign tumor with a distinct serum reactivity pattern and a decline of complexity with malignancy.
  • [MeSH-major] Antibodies, Neoplasm / blood. Antibody Formation / immunology. Antigens, Neoplasm / immunology. Meningioma / immunology

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  • (PMID = 15983380.001).
  • [ISSN] 0027-8424
  • [Journal-full-title] Proceedings of the National Academy of Sciences of the United States of America
  • [ISO-abbreviation] Proc. Natl. Acad. Sci. U.S.A.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Neoplasm; 0 / Antigens, Neoplasm; 0 / DNA Primers
  • [Other-IDs] NLM/ PMC1172238
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70. Huang HZ, Huang ZQ, Zhao XP, Zhang B: [Intraoral submandibular gland excision and how to deal with external maxillary artery]. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2006 Jul;41(7):514-6
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  • CONCLUSION: Intraoral submandibular gland excision is safe and feasible for chronic sialadenitis and cyst of submandibular gland and some of benign tumor submandibular gland as long as indications strictly controlled and the external maxillary artery well coped with.

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  • (PMID = 17007375.001).
  • [ISSN] 1673-0860
  • [Journal-full-title] Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery
  • [ISO-abbreviation] Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
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71. Zarbis N, Barth TF, Blumstein NM, Schelzig H: Pecoma of the lung: a benign tumor with extensive 18F-2-deoxy-D-glucose uptake. Interact Cardiovasc Thorac Surg; 2007 Oct;6(5):676-8
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  • [Title] Pecoma of the lung: a benign tumor with extensive 18F-2-deoxy-D-glucose uptake.
  • Pecomas of the lung--which include the better known clear cell 'sugar' tumor--are a subset of extremely rare lung tumors which usually react positively to both melanocytic and smooth muscle markers.
  • Although widely presumed as benign in computed tomography (CT) and positron emission tomography (PET)/CT studies they depict as malignant, thus complicating the preoperative diagnosis.

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  • (PMID = 17670735.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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72. Zhao J, Wu W, Wang J, Liu L, Han D: [Clinical observation of 116 cases of laryngofissure avoiding tracheotomy]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Feb;24(3):114-5
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  • RESULT: Of 116 cases, 101 cases had the laryngeal carcinoma; 9 cases had laryngeal stenosis; 6 cases had benign tumor of larynx.
  • No recurrence in 6 cases of benign tumor of larynx.

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  • (PMID = 20429381.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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73. Jidveianu NH, Puscasiu L, Vonica OC: Newborn's giant sacrococcigeal teratoma. Chirurgia (Bucur); 2010 May-Jun;105(3):423-5
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  • A sacrococcigeal tumor was detect at ultrasound maternal exam in 25TH week of pregnancy.
  • The newborn present a tumor with 12 cm diameter, situated in sacrococcigeal region, with a large base of implantation and with posteroinferior growth.
  • This tumor produced a dislocation of the rectum and a perineal area.
  • We removed a large tumor (600 gr) with the coccys bone and we obtained a good repair of anatomy of the region, without postoperatory functional troubles.
  • The histopatologic exam confirmed that the tumor was benign.
  • [MeSH-minor] Female. Humans. Infant, Newborn. Pregnancy. Sacrococcygeal Region. Treatment Outcome

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  • (PMID = 20726314.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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74. Yavisheva TM, Shcherbakov SD, Golubeva IS, Savluchinskaya LA: Comparative analysis of the work of morphofunctional zones in normal epithelium, fibroadenoma, and cancer of the breast. Bull Exp Biol Med; 2005 Aug;140(2):231-4
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  • The number of cambial cells in morphofunctional zone of a malignant tumor is reduced at least 2-fold.
  • The percentage of cambial cells in a benign tumor decreases 1.5 times.

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  • (PMID = 16283009.001).
  • [ISSN] 0007-4888
  • [Journal-full-title] Bulletin of experimental biology and medicine
  • [ISO-abbreviation] Bull. Exp. Biol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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75. Konan KE, Diabate AS, N'Guessan ND, Anzouan KE, Yapi-Yapo CP, Assouan C, Assa A, Ouattara DN: [Diagnostic and surgical approach to an hourglass-shaped nasopalatine glioma in an infant]. Odontostomatol Trop; 2010 Sep;33(131):5-10
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  • It is a benign tumor that fits into the nosology of the masses of the midline.
  • Histology examination of the surgical specimen confirmed the nature of astrocytic neuroglial tumor.
  • The location of the tumor pedide palate to that of the left nostril is special and especially histological diagnosis of this congenital malformation.

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  • (PMID = 21328923.001).
  • [ISSN] 0251-172X
  • [Journal-full-title] Odonto-stomatologie tropicale = Tropical dental journal
  • [ISO-abbreviation] Odontostomatol Trop
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Senegal
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76. Bioulac-Sage P, Laumonier H, Laurent C, Blanc JF, Balabaud C: Benign and malignant vascular tumors of the liver in adults. Semin Liver Dis; 2008 Aug;28(3):302-14
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  • [Title] Benign and malignant vascular tumors of the liver in adults.
  • Vascular tumors of the liver in adult patients include cavernous hemangioma, a common benign tumor; epithelioid hemangioendothelioma, a rare, usually low-grade malignant tumor; and angiosarcoma, a rare and very aggressive tumor.
  • Hemangioma follows a benign course, and a nonoperative approach for the majority of these lesions is recommended.

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  • (PMID = 18814083.001).
  • [ISSN] 0272-8087
  • [Journal-full-title] Seminars in liver disease
  • [ISO-abbreviation] Semin. Liver Dis.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 45
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77. Zatonski T, Bolanowski M, Skrzypek A, Morawska-Kochman M, Kaluzny M, Zatonska K, Moron K, Badowski R, Krecicki T: Evaluation of temporal bone computed tomography and paranasal sinuses magnetic resonance images in acromegalic patients. Neuro Endocrinol Lett; 2010;31(6):796-800
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  • OBJECTIVE: Acromegaly is a rare disease, which symptoms are caused by excess secretion of a growth hormone (GH) from the anterior pituitary benign tumor - adenoma.

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  • (PMID = 21206436.001).
  • [ISSN] 0172-780X
  • [Journal-full-title] Neuro endocrinology letters
  • [ISO-abbreviation] Neuro Endocrinol. Lett.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Sweden
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78. Popovska S: [Granular cell tumor of the breast--review of the literature and research for a period of 5 years]. Khirurgiia (Sofiia); 2006;(1):53-5
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  • [Title] [Granular cell tumor of the breast--review of the literature and research for a period of 5 years].
  • Granular cell tumor is relatively rare neoplasm, and always benign in its prognostic behavior.
  • Location of this tumor in the breast presents serious problems for differential diagnosis, both from a clinical point of view and at gross pathologic examination, because of its resemblance to carcinoma.
  • [MeSH-major] Breast Neoplasms / pathology. Granular Cell Tumor / pathology

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  • (PMID = 18771140.001).
  • [ISSN] 0450-2167
  • [Journal-full-title] Khirurgii︠a︡
  • [ISO-abbreviation] Khirurgiia (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Bulgaria
  • [Number-of-references] 11
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79. Paiva Nunes A, Mendes I, Godinho T, Lourenço I, Jordão A, Gorjão Clara J: [Solitary fibrous tumor of the pleura]. Rev Port Cir Cardiotorac Vasc; 2007 Oct-Dec;14(4):203-5
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  • [Title] [Solitary fibrous tumor of the pleura].
  • [Transliterated title] Tumor fibroso solitário da pleura.
  • In half of the cases, the neoplasm presents as an asymptomatic mass, often with quite large dimensions.
  • It is a benign tumor in 80% of the cases and even when considered malignant has a good prognosis if totally removed.
  • We present the case of a 78-year-old female, who was evaluated for lower respiratory infection, in whom the diagnosis of Giant Solitary Fibrous Tumor of the Pleura was made.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural

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  • (PMID = 18408817.001).
  • [ISSN] 0873-7215
  • [Journal-full-title] Revista portuguesa de cirurgia cardio-torácica e vascular : órgão oficial da Sociedade Portuguesa de Cirurgia Cardio-Torácica e Vascular
  • [ISO-abbreviation] Rev Port Cir Cardiotorac Vasc
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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80. Hodges JM, McDevitt AS, El-Sayed Ali AI, Sebelik ME: Juvenile nasopharyngeal angiofibroma: current treatment modalities and future considerations. Indian J Otolaryngol Head Neck Surg; 2010 Sep;62(3):236-47
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  • Juvenile angiofibroma (JNA) is a relatively uncommon, highly vascular and benign tumor that presents most commonly in adolescent males.

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  • (PMID = 23120720.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450247
  • [Keywords] NOTNLM ; Angiofibroma / Cyberknife / Embolization / Endoscopic surgery / IMRT / Image guided robotic radiotherapy / Skull base / Vascular tumor
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81. Białas M, Szczepański W, Szpor J, Okoń K, Kostecka-Matyja M, Hubalewska-Dydejczyk A, Tomaszewska R: Adenomatoid tumour of the adrenal gland: a case report and literature review. Pol J Pathol; 2010;61(2):97-102
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  • Adenomatoid tumour (AT) is a rare, benign neoplasm of mesothelial origin, which usually occurs in the genital tract of both sexes.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Asymptomatic Diseases. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Incidental Findings. Male. Radiography, Abdominal. Tomography, X-Ray Computed

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  • (PMID = 20924994.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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82. Hsu TL, Changchien CC, Huang CC, Lin H: Angioleiomyoma originating from the ovary of an eleven-year-old premenarchal girl. Gynecol Obstet Invest; 2008;65(4):262-5
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  • BACKGROUND: Angioleiomyoma (ALM) is a rare, benign neoplasm involving the peripheral soft tissues.
  • The final pathologic report of the resected tumor was consistent with an ALM.

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  • [Copyright] (c) 2008 S. Karger AG, Basel
  • [CommentIn] Gynecol Obstet Invest. 2010;70(1):8-10 [20130412.001]
  • (PMID = 18196910.001).
  • [ISSN] 1423-002X
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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83. Edelweiss M, Gupta N, Resetkova E: Preoperative diagnosis of clear cell "sugar" tumor of the lung by computed tomography-guided fine-needle biopsy and core-needle biopsy. Ann Diagn Pathol; 2007 Dec;11(6):421-6
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  • [Title] Preoperative diagnosis of clear cell "sugar" tumor of the lung by computed tomography-guided fine-needle biopsy and core-needle biopsy.
  • Clear cell "sugar" tumor (CCST) of the lung is a very rare benign neoplasm believed to arise from epithelioid cells of perivascular differentiation.
  • This tumor is typically diagnosed by thoracotomy.

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  • (PMID = 18022127.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Atallah D, Checrallah A, Rouzier R, Ghossain MA, Chahine G: Retroperitoneal lymphangioleiomyoma mimicking ovarian tumor emerging after tamoxifen therapy. Obstet Gynecol; 2006 Sep;108(3 Pt 2):762-4
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  • [Title] Retroperitoneal lymphangioleiomyoma mimicking ovarian tumor emerging after tamoxifen therapy.
  • We speculate that tamoxifen treatment may play a role in the development of this benign tumor.

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  • Hazardous Substances Data Bank. TAMOXIFEN .
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  • (PMID = 17018494.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 094ZI81Y45 / Tamoxifen
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85. Chadha M, Agarwal A, Wadhwa N: Chondroid chordoma of the L5 spinous process and lamina: a case report. Eur Spine J; 2005 Oct;14(8):803-6
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  • Chordoma is a rare bone tumor that originates from the remnants of the notochord.
  • A differential diagnosis of a benign tumor (giant cell tumor, aneurysmal bone cyst or osteoblastoma) was made initially.
  • The tumor was removed enbloc.
  • Histopathological examination revealed the tumor mass to be chordoma.

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  • [Cites] Spine (Phila Pa 1976). 2000 Oct 1;25(19):2537-40 [11013508.001]
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  • (PMID = 15895260.001).
  • [ISSN] 0940-6719
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC3489257
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86. Leal D, Fariña L, Pesqueira D, Meijide F, Quintana JL, Muller C, Regojo JM, Antón I: [Testicular epidermoid cyst]. Actas Urol Esp; 2010 Mar;34(3):274-7
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  • Epidermoid cyst of the testis is a rare benign tumor, and its differential diagnosis from malignant testicular tumors is difficult.

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  • (PMID = 20416245.001).
  • [ISSN] 1699-7980
  • [Journal-full-title] Actas urologicas españolas
  • [ISO-abbreviation] Actas Urol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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87. Hsiao KH, Lin LH, Chen DF, Huang SH: Hepatic mesenchymal hamartoma combined with infantile hepatic hemangioendothelioma in an infant. J Formos Med Assoc; 2007 Mar;106(3 Suppl):S1-4
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  • Hepatic mesenchymal hamartoma is a rare benign tumor in children, and infantile hepatic hemangioendothelioma is also a rare liver neoplasm.
  • Three tumor masses were detected this time, and the serum alpha-fetoprotein (AFP) was 6700 ng/mL.
  • After half a year of regular follow-up, the AFP level decreased gradually to 79.5 ng/mL, without evidence of tumor recurrence.

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  • (PMID = 17493912.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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88. Fotiadis E, Akritopoulos P, Samoladas E, Akritopoulou K, Kenanidis E: Chondromyxoid fibroma: a rare tumor with an unusual location. Arch Orthop Trauma Surg; 2008 Apr;128(4):371-5
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  • [Title] Chondromyxoid fibroma: a rare tumor with an unusual location.
  • Chondromyxoid fibroma constitutes a rare benign tumor of the bones, which has a potential of regional enlargement towards the local tissues.
  • After the removal of the tumor with curettage, both with curette and with a high-speed burr, osseous cement was placed in the cavity of the lesion.
  • The biopsy of the tumor confirmed the diagnosis of the chondromyxoid fibroma.
  • This is the first unusual location of the tumor in the national bibliography.
  • The patient after 5 years post-operatively does not show either clinical or radiological signs of regional recurrence of the tumor.

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  • (PMID = 17342522.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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89. Aoun N, Zafatayeff S, Smayra T, Haddad-Zebouni S, Tohmé C, Ghossain M: Adenomyoma of the ampullary region: imaging findings in four patients. Abdom Imaging; 2005 Jan-Feb;30(1):86-9
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  • BACKGROUND: We report the imaging features of adenomyoma of the distal common bile duct (CBD) and increase awareness of this rare benign disease.
  • CONCLUSION: Although imaging findings are not specific, their presence should raise the possibility of a benign tumor.

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  • (PMID = 15647876.001).
  • [ISSN] 0942-8925
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Yang J, Wang D: [Clinical value of tumor-associated growth factor detection in the diagnosis of colorectal carcinoma]. Nan Fang Yi Ke Da Xue Xue Bao; 2007 Oct;27(10):1577-9
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  • [Title] [Clinical value of tumor-associated growth factor detection in the diagnosis of colorectal carcinoma].
  • OBJECTIVE: To investigate the diagnostic value of tumor-supplied growth factors (TSGF) in patients with colorectal carcinoma.
  • METHODS: The serum content of TSGF was determined in 71 patients with colorectal carcinoma 71, 55 with benign tumor, and 100 healthy volunteers with colorimetry.
  • RESULTS: TSGF concentration and its positivity rate were both significantly higher in colorectal carcinoma patients (81.5 x 10(3) U/L/71%) than in normal controls (55.7 x 10(3) U/L/3%) and patients with benign tumor (57.2 x 10(3)U/L/7.4%).TSGF positivity rate was independent of the patients' age, gender and stage of colorectal carcinoma.
  • [MeSH-major] Biomarkers, Tumor / blood. Colorectal Neoplasms / blood

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  • (PMID = 17959542.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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91. Bakari A, Afolabi OA, Adoga AA, Kodiya AM, Ahmad BM: Clinico-pathological profile of sinonasal masses: an experience in national ear care center Kaduna, Nigeria. BMC Res Notes; 2010;3:186
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  • About 59 (77.6%) were benign, 2 (2.6%) were malignant and 15 (19.7%) were lost to follow up.
  • CONCLUSIONS: Nasal obstruction and rhinorrhea are the commonest symptoms of presentation, simple inflammatory nasal polyp is still the commonest histological pattern seen in our environment, and surgery is still the best modality of treatment for benign tumor thus the need for advocacy for early recognition and referral to the ENT surgeon.

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  • [Cites] Can Fam Physician. 1988 Dec;34:2706-9 [20469495.001]
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  • (PMID = 20618972.001).
  • [ISSN] 1756-0500
  • [Journal-full-title] BMC research notes
  • [ISO-abbreviation] BMC Res Notes
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2916008
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92. Zhang J, Chen AP, Wang B, Zhao SP, Liu LZ, Dai SZ: [Correlations of EGFR and LRP to chemotherapy resistance and prognosis of ovarian cancer]. Ai Zheng; 2008 Dec;27(12):1331-6
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  • BACKGROUND & OBJECTIVE: Abnormal expression and activation of epidermal growth factor receptor (EGFR), which is closely related to the recurrence and poor prognosis of ovarian cancer, can promote chemotherapy resistance of tumor cells.
  • METHODS: Expressions of EGFR and LRP in 76 specimens of ovarian malignant tumor, nine borderline tumor, 17 benign tumor and 15 normal ovary were studied using immunohistochemistry.
  • RESULTS: The positive rates of EGFR and LRP in malignant specimens (73.68% and 71.79%) were significantly higher than those in normal and benign ones (P <0.01).
  • [MeSH-major] Cystadenocarcinoma, Serous / metabolism. Drug Resistance, Neoplasm. Ovarian Neoplasms / metabolism. Receptor, Epidermal Growth Factor / metabolism. Vault Ribonucleoprotein Particles / metabolism
  • [MeSH-minor] Antineoplastic Combined Chemotherapy Protocols / therapeutic use. Cisplatin / administration & dosage. Cisplatin / pharmacology. Cystadenocarcinoma, Mucinous / drug therapy. Cystadenocarcinoma, Mucinous / metabolism. Cystadenocarcinoma, Mucinous / pathology. Cystadenoma, Mucinous / drug therapy. Cystadenoma, Mucinous / metabolism. Cystadenoma, Mucinous / pathology. Cystadenoma, Serous / drug therapy. Cystadenoma, Serous / metabolism. Cystadenoma, Serous / pathology. Female. Follow-Up Studies. Humans. Middle Aged. Neoplasm Staging. Survival Rate


93. Kollová A, Liscák R, Novotný J Jr, Vladyka V, Simonová G, Janousková L: Gamma Knife surgery for benign meningioma. J Neurosurg; 2007 Aug;107(2):325-36
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  • [Title] Gamma Knife surgery for benign meningioma.
  • OBJECT: Meningioma is the most frequent benign tumor treated with Gamma Knife surgery (GKS); however, the assessment of its efficacy and safety in slow-growing tumors is an ongoing process, requiring analysis of long-term results.
  • The median tumor volume was 4.4 cm3 (range 0.11-44.9 cm3).
  • The median tumor margin dose to the 50% isodose line was 12.55 Gy (range 6.5-24 Gy).
  • The actuarial tumor control rate was 97.9% at 5 years post-GKS.
  • RESULTS: A significantly higher incidence of tumor volume increase was observed in men compared with women and in tumors treated with a margin dose lower than 12 Gy.
  • Significant risk factors for edema included an age greater than 60 years, no previous surgery, perilesional edema before radiosurgery, a tumor volume greater than 10 cm3, a tumor location in the anterior fossa, and a margin dose greater than 16 Gy.
  • A minimum margin dose of 12 to 16 Gy seems to represent the therapeutic window for benign meningiomas with a high tumor control rate in a mid-term follow-up period.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Male. Middle Aged. Retrospective Studies. Time Factors. Treatment Outcome. Tumor Burden

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  • (PMID = 17695387.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Hansen SL, Dosanjh A, Young DM, Boudreau N, Hoffman WY: Hemangiomas and homeobox gene expression. J Craniofac Surg; 2006 Jul;17(4):767-71
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  • Hemangiomas are the most common benign tumor of childhood.
  • Homeobox (Hox) genes are master transcription factors, which have a centrol role during organogenesis, and more recently have been documented to be involved in postnatal tissue remodeling and tumor angiogenesis.

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  • (PMID = 16877932.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / F32GM2084901; United States / PHS HHS / / K0-8 G00674; United States / NIGMS NIH HHS / GM / P50GM27345
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cytokines; 0 / DNA-Binding Proteins; 0 / Homeodomain Proteins; 0 / Transcription Factors; 127609-92-1 / HOXA4 protein, human
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95. El Idrissi F, Fadli A: [Erosive adenomatosis of the nipple]. J Gynecol Obstet Biol Reprod (Paris); 2005 Dec;34(8):813-4
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  • First rule out galactophoric carcinoma underlying all the erosions of the nipple or a breast tumor.
  • A 52-year-old woman consulted for a right breast tumor that had developing for more than four years due to a serious nipple flow.
  • Physical examination disclosed an ulcer tumor of the nipple and the superior quadrant of the areole.
  • Wide tumor resection was performed.
  • Erosive adenomatosis of the nipple is a benign tumor which developing within the lactic nipple.
  • Erosive adenomatosis of the nipple is very rare and should be suspected in patients with nipple erosions or a nipple tumor.

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  • (PMID = 16319774.001).
  • [ISSN] 0368-2315
  • [Journal-full-title] Journal de gynécologie, obstétrique et biologie de la reproduction
  • [ISO-abbreviation] J Gynecol Obstet Biol Reprod (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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96. Idrees MT, Deligdisch L, Altchek A: Squamous papilloma with hyperpigmentation in the skin graft of the neovagina in Rokitansky syndrome: literature review of benign and malignant lesions of the neovagina. J Pediatr Adolesc Gynecol; 2009 Oct;22(5):e148-55
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  • [Title] Squamous papilloma with hyperpigmentation in the skin graft of the neovagina in Rokitansky syndrome: literature review of benign and malignant lesions of the neovagina.
  • BACKGROUND: It is rare for a benign or malignant neoplasm to develop in a neovagina.
  • Despite the dark color of the vaginal lesion, bleeding and rapid appearance our patient had a benign tumor.

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  • (PMID = 19616457.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 46
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97. Taira N, Aogi K, Ohsumi S, Takashima S, Kawamura S, Nishimura R: Epidermal inclusion cyst of the breast. Breast Cancer; 2007;14(4):434-7
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  • Mammography revealed a round and smoothly outlined mass, which indicated a benign tumor, and sonography showed an irregularly shaped and heterogeneous hypoechoic mass.
  • A phyllodes tumor or a giant fibroadenoma was suspected on the basis of clinical and imaging findings, but the resected specimen revealed an epidermal inclusion cyst.

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  • (PMID = 17986812.001).
  • [ISSN] 1880-4233
  • [Journal-full-title] Breast cancer (Tokyo, Japan)
  • [ISO-abbreviation] Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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98. Nah YW, Suh JH, Choi DH, Ko BK, Nam CW, Kim GY, Im YC, Cho HR: Benign retroperitoneal schwannoma: surgical consideration. Hepatogastroenterology; 2005 Nov-Dec;52(66):1681-4
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  • [Title] Benign retroperitoneal schwannoma: surgical consideration.
  • Schwannoma, which arises from the neural sheath of peripheral nerves, is the most common benign tumor in the retroperitoneum in adults.
  • There are few vessels, if any, on the anterior and lateral surfaces of the tumor.
  • In conclusion, considering such multiple small tumor vessels running adjacent to the aorta, the surgeon should pay close attention to the course of central dissection of these tumors in the retroperitoneum.
  • [MeSH-minor] Adult. Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Korea. Laparoscopy / methods. Laparotomy / methods. Middle Aged. Neoplasm Staging. Retrospective Studies. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome. Ultrasonography, Doppler

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  • (PMID = 16334756.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
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99. Krengel S: Nevogenesis--new thoughts regarding a classical problem. Am J Dermatopathol; 2005 Oct;27(5):456-65
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  • As a consequence, there are two main perspectives to nevi: that of a hamartoma and that of a benign tumor.
  • In this review, dermatopathological studies on congenital and acquired nevi, including studies on age-related and location-dependent changes, are analyzed.

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  • (PMID = 16148419.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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100. Liu J, Zheng S, Yu JK, Zhang JM, Chen Z: Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor. J Zhejiang Univ Sci B; 2005 Jan;6(1):4-10
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  • [Title] Serum protein fingerprinting coupled with artificial neural network distinguishes glioma from healthy population or brain benign tumor.
  • To screen and evaluate protein biomarkers for the detection of gliomas (Astrocytoma grade I-IV) from healthy individuals and gliomas from brain benign tumors by using surface enhanced laser desorption/ionization time of flight mass spectrometry (SELDI-TOF-MS) coupled with an artificial neural network (ANN) algorithm.
  • SELDI-TOF-MS protein fingerprinting of serum from 105 brain tumor patients and healthy individuals, included 28 patients with glioma (Astrocytoma I-IV), 37 patients with brain benign tumor, and 40 age-matched healthy individuals.
  • An accuracy of 95.7%, sensitivity of 88.9%, specificity of 100%, positive predictive value of 90% and negative predictive value of 100% were obtained in a blinded test set comparing gliomas patients with healthy individuals; an accuracy of 86.4%, sensitivity of 88.9%, specificity of 84.6%, positive predictive value of 90% and negative predictive value of 85.7% were obtained when patient's gliomas was compared with benign brain tumor.
  • The high sensitivity and specificity achieved by the use of selected biomarkers showed great potential application for the discrimination of gliomas patients from healthy individuals and gliomas from brain benign tumors.
  • [MeSH-major] Astrocytoma / blood. Astrocytoma / diagnosis. Biomarkers, Tumor / blood. Brain Neoplasms / blood. Brain Neoplasms / diagnosis. Diagnosis, Computer-Assisted / methods. Neoplasm Proteins / blood. Peptide Mapping / methods

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  • (PMID = 15593384.001).
  • [ISSN] 1673-1581
  • [Journal-full-title] Journal of Zhejiang University. Science. B
  • [ISO-abbreviation] J Zhejiang Univ Sci B
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Controlled Clinical Trial; Letter; Research Support, Non-U.S. Gov't; Validation Studies
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
  • [Other-IDs] NLM/ PMC1390751
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