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Items 1 to 100 of about 260
1. Wakoh M, Yonezu H, Otonari T, Sano T, Matsuzaka K, Inoue T, Wada N: Two cases of schwannoma with marked cystic changes. Dentomaxillofac Radiol; 2005 Jan;34(1):44-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The extirpated tumour specimen measured 58 mm x 58 mm x 30 mm.
  • Panoramic radiography and lateral oblique mandible projection, which were used together with conventional sialography of the submandibular gland, revealed the so-called "ball in hand" appearance of the submandibular gland, and contrast-enhanced CT identified a lesion of 30 mm diameter with a well-defined annular margin and homogeneous low-density near the tumour centre.
  • Benign pleomorphic adenoma was suspected, but histopathological examination identified schwannoma, predominantly comprising Antoni B type tissue.
  • [MeSH-minor] Adult. Female. Humans. Lymph Nodes / pathology. Lymph Nodes / radiography. Magnetic Resonance Imaging. Male. Middle Aged. Neck / pathology. Neck / radiography. Temporal Muscle / pathology

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  • (PMID = 15709106.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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2. Suárez C, Rodrigo JP, Ferlito A, Cabanillas R, Shaha AR, Rinaldo A: Tumours of familial origin in the head and neck. Oral Oncol; 2006 Nov;42(10):965-78
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumours of familial origin in the head and neck.
  • Individuals with inherited cancer syndromes are at significant risk of developing both benign and malignant tumours as a result of a germline mutation in a specific tumour suppressor gene.
  • Tumours of familial origin are a rare event in the head and neck but despite this, they deserve a growing interest.
  • No clear correlation of MEN-1 genotype with genotype has emerged to date, and MEN-1 mutation testing in tumours is not used clinically because it have not implications for tumour staging.
  • Multiple endocrine neoplasia type 2 is due to a germline mutation in the RET proto-oncogene.
  • The elucidation of the cellular processes affected by dysfunction in familial tumours of the head and neck may serve to identify potential targets for future therapeutic interventions.
  • [MeSH-major] Head and Neck Neoplasms / genetics. Neoplastic Syndromes, Hereditary / genetics
  • [MeSH-minor] Carcinoma, Squamous Cell / genetics. Humans. Multiple Endocrine Neoplasia / genetics. Nasopharyngeal Neoplasms / genetics. Neurofibromatoses / genetics. Paraganglioma / genetics

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  • (PMID = 16857415.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 121
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3. Betz CS, Jäger HR, Brookes JA, Richards R, Leunig A, Hopper C: Interstitial photodynamic therapy for a symptom-targeted treatment of complex vascular malformations in the head and neck region. Lasers Surg Med; 2007 Aug;39(7):571-82
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  • [Title] Interstitial photodynamic therapy for a symptom-targeted treatment of complex vascular malformations in the head and neck region.
  • The photosensitizing drug Foscan is licensed in the EU for the treatment of advanced head and neck cancer.
  • The light can be applied by surface illumination or directly into tumour tissue by optical fibres.
  • This raises the possibility of using this therapy in the treatment of benign neoplasms in the head and neck.
  • CONCLUSION: This minimally invasive approach to treat complex benign neoplasias seems promising.
  • [MeSH-minor] Adult. Diagnosis, Differential. Follow-Up Studies. Head. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neck. Retrospective Studies. Tomography, X-Ray Computed

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  • (PMID = 17868106.001).
  • [ISSN] 0196-8092
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Mesoporphyrins; 0 / Photosensitizing Agents; FU21S769PF / temoporfin
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4. Koumanis DJ, Glickman LT: Facial neurothekeoma in a 10-year-old child. Can J Plast Surg; 2007;15(3):175-7
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  • Neurothekeoma is a rare and benign tumour that occurs most frequently on the head and neck.
  • It is classified as a nerve sheath tumour and epidemiologically occurs in young adults.

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  • [Cites] J Dermatol. 1999 Jun;26(6):363-7 [10405481.001]
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  • (PMID = 19554154.001).
  • [ISSN] 1195-2199
  • [Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique
  • [ISO-abbreviation] Can J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2687505
  • [Keywords] NOTNLM ; Immunohistochemistry / Nerve sheath tumour / Neurothekeoma / Reconstructive surgery
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5. Kanzaki S, Nameki H: Standardised method of selecting surgical approaches to benign parapharyngeal space tumours, based on pre-operative images. J Laryngol Otol; 2008 Jun;122(6):628-34
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  • [Title] Standardised method of selecting surgical approaches to benign parapharyngeal space tumours, based on pre-operative images.
  • In order to determine the best surgical approach for each tumour, we first subdivided the parapharyngeal space into six compartments, based on anatomical landmarks seen on computed tomography and/or magnetic resonance imaging scans.
  • We then determined the location of each tumour relative to these six parapharyngeal space compartments.
  • To remove a large tumour in the middle and inferior portion of the parapharyngeal space, a transparotid approach was the most suitable.
  • Finally, a tumour in the inferior portion of the parapharyngeal space was best accessed through a transcervical approach.

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  • (PMID = 17655777.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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6. Fei Z, Zhang X, Jiang XF, Liu WP, Wang XL, Xie L: Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation. J Craniomaxillofac Surg; 2007 Jan;35(1):30-4
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  • [Title] Removal of large benign cephalonasal tumours by transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation.
  • In 20 cases neuronavigation was used in addition to locate the tumour and adjoining structures.
  • RESULTS: Twenty-seven cases had a complete removal of the tumour whilst the others had only a subtotal resection.
  • CONCLUSION: Transbasal surgery combined with endonasal endoscopic sinus surgery and neuronavigation is a particularly useful technique for resecting large benign cephalonasal tumours.
  • [MeSH-major] Endoscopy / methods. Head and Neck Neoplasms / surgery. Neuronavigation / methods. Skull Base / surgery
  • [MeSH-minor] Abducens Nerve Diseases / etiology. Adolescent. Adult. Child. Child, Preschool. Deglutition Disorders / etiology. Female. Follow-Up Studies. Humans. Male. Middle Aged. Nasal Cavity / surgery. Neoplasm Recurrence, Local / surgery. Neoplasm, Residual / pathology. Nose Neoplasms / surgery. Olfaction Disorders / etiology. Ophthalmoplegia / etiology. Paralysis / etiology. Paranasal Sinus Neoplasms / surgery. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Skull Base Neoplasms / surgery

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  • (PMID = 17261369.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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7. Sevilla García MA, Llorente Pendás JL, Rodrigo Tapia JP, García Rostán G, Suárez Fente V, Coca Pelaz A, Suárez Nieto C: [Head and neck paragangliomas: revision of 89 cases in 73 patients]. Acta Otorrinolaringol Esp; 2007 Mar;58(3):94-100
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  • [Title] [Head and neck paragangliomas: revision of 89 cases in 73 patients].
  • [Transliterated title] Paragangliomas de cabeza y cuello: revisión de 89 casos en 73 pacientes.
  • PGL are usually clinically benign tumours, although metastasis has been reported and invasive growth can occur in adjacent tissues (<10 %).
  • The surgical approach was evaluated in terms of tumour origin, sequelae, and subsequent evolution, as well as the relapses and their relation with location of the primary tumour.
  • CONCLUSIONS: With this article we try to reflect our experience in the treatment of this type of tumour.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Paraganglioma / pathology

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  • (PMID = 17371691.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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8. Johnson MA, Rajendran S, Balachandar TG, Kannan DG, Jeswanth S, Ravichandran P, Surendran R: Central pancreatectomy for benign pancreatic pathology/trauma: is it a reasonable pancreas-preserving conservative surgical strategy alternative to standard major pancreatic resection? ANZ J Surg; 2006 Nov;76(11):987-95
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  • [Title] Central pancreatectomy for benign pancreatic pathology/trauma: is it a reasonable pancreas-preserving conservative surgical strategy alternative to standard major pancreatic resection?
  • BACKGROUND: The aim of this study was to assess the technical feasibility, safety and outcome of central pancreatectomy (CP) with pancreaticogastrostomy or pancreaticojejunostomy in appropriately selected patients with benign central pancreatic pathology/trauma.
  • Benign lesions/trauma of the pancreatic neck and proximal body pose an interesting surgical challenge.
  • CP is an operation that allows resection of benign tumours located in the pancreatic isthmus that are not suitable for enucleation.
  • The indications for CP were: non-functional islet cell tumours in two patients, traumatic pancreatic neck transection in two and one each for insulinoma, solid pseudopapillary tumour, splenic artery pseudoaneurysm and pseudocyst.
  • CONCLUSION: When technically feasible, CP is a safe, pancreas-preserving pancreatectomy for non-enucleable benign pancreatic pathology/trauma confined to pancreatic isthmus that allows for cure of the disease without loss of substantial amount of normal pancreatic parenchyma with preservation of exocrine/endocrine function and without interruption of enteric continuity.

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  • [CommentIn] ANZ J Surg. 2006 Nov;76(11):959-60 [17054540.001]
  • (PMID = 17054548.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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9. Eloy-Garcia Carrasco C, Benguigui Benadiva J, Martinez Garcia S, Sanz Trelles A, Palacios S: Atypical primary carcinoid tumour of the skin. J Cutan Pathol; 2006 Sep;33 Suppl 2:32-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Atypical primary carcinoid tumour of the skin.
  • We present a new case of a primary carcinoid tumour of the skin.
  • Literature review showed this to be only the seventh case of primary carcinoid tumour of the skin.
  • Although the number of cases is too small to draw definitive conclusions, information to date suggests that this type of tumour can be expected to have a benign behaviour, despite the presence in some cases of criteria suggestive of uncertainty, such as the presence of mitosis.
  • [MeSH-major] Carcinoid Tumor / pathology. Head and Neck Neoplasms / pathology. Skin Neoplasms / pathology

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  • (PMID = 16972951.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Denmark
  • [Number-of-references] 7
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10. Ram H, Mohammad S, Husain N, Gupta PN: Ameloblastic carcinoma. J Maxillofac Oral Surg; 2010 Dec;9(4):415-9
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  • Ameloblastic carcinoma (AC) is a rare aggressive malignant epithelial odontogenic tumor of the maxillofacial skeleton with a distinct predilection in the mandible.
  • It may present as a cystic lesion with benign clinical features or as a large tissue mass with ulceration, significant bone resorption and tooth mobility.
  • Direct extension of the tumour, lymph node involvement and metastasis to various sites has been reported.

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  • (PMID = 22190836.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3177477
  • [Keywords] NOTNLM ; Ameloblastic carcinoma / Ameloblastoma / Odontogenic tumor
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11. Karonidis A, Rigby HS, Orlando A: Collagenosis Nuchae: a case report of a rare and often misdiagnosed condition. J Plast Reconstr Aesthet Surg; 2007;60(3):320-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CN is a rare benign soft tissue tumour that arises from the posterior cervical subcutaneous tissue with predilection for the interscapular and paraspinal regions.
  • The true incidence of CN is probably higher than recognised and CN should be in the differential diagnosis of head and neck lesions.
  • [MeSH-major] Fibroma / diagnosis. Head and Neck Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 17293293.001).
  • [ISSN] 1748-6815
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 10
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12. Shaw CK, Sood S, Bradley PJ, Krishnan S: Unusual mass in the parapharyngeal space: a Warthin's tumour. ANZ J Surg; 2006 Mar;76(3):193-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Unusual mass in the parapharyngeal space: a Warthin's tumour.
  • Warthin's tumour, another benign salivary tumour involving the PPS has been rarely reported.
  • A case of bilateral, metachronous Warthin's tumour involving the PPS is reported here.
  • PPS Warthin's tumour is a very rare condition that if undiagnosed may result in considerable morbidity.
  • [MeSH-minor] Aged. Female. Humans. Neoplasm Invasiveness. Parotid Gland / surgery. Tomography, X-Ray Computed

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  • (PMID = 16626365.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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13. Sharma V, Koirala K: Lateral rhinotomy vs mid-facial degloving for T3 inverted papilloma of nose and paranasal sinus. Nepal Med Coll J; 2009 Jun;11(2):115-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Inverted papillomas are rare, benign epithelial tumours of the nasal cavity and paranasal sinuses.
  • All patients initially underwent nasal biopsy for confirmation of the diagnosis and pre-operative C.T. scan for tumour staging.
  • [MeSH-minor] Aged. Biopsy. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 19968152.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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14. Gupta M, Motwani G, Gupta P: Extranasopharyngeal angiofibroma arising from the infratemporal region. Indian J Otolaryngol Head Neck Surg; 2006 Jul;58(3):312-5
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  • Angiofibroma is a histologically benign but locally invasive tumour of the blood vessels characterized by architecturally irregular vessels set in a fibrous stroma.
  • The likely theory of origin of the tumour and its management is also discussed.

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  • (PMID = 23120330.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450408
  • [Keywords] NOTNLM ; Extranasopharyngeal angiofibroma
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15. Zhang GY, Ahmed N, Riley C, Oliva K, Barker G, Quinn MA, Rice GE: Enhanced expression of peroxisome proliferator-activated receptor gamma in epithelial ovarian carcinoma. Br J Cancer; 2005 Jan 17;92(1):113-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A total of 56 ovarian specimens including 10 normal, eight benign, 10 borderline, seven grade 1, nine grade 2 and 12 grade 3 were analysed using immunohistochemistry.
  • Out of eight benign and 10 borderline tumours, only one tumour in each group showed weak cytoplasmic PPARgamma expression.
  • Significantly increased PPARgamma immunoreactivity was observed in malignant ovarian tumours (grade 1, 2 and 3) compared to benign and borderline tumours (chi2 = 48.80, P < 0.001).
  • Western blot analyses showed significant elevation in the expression of immunoreactive PPARgamma in grade 3 ovarian tumours compared with that of normal ovaries and benign ovarian tumours (P < 0.01).

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  • (PMID = 15583697.001).
  • [ISSN] 0007-0920
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / PPAR gamma
  • [Other-IDs] NLM/ PMC2361744
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16. Frosini P, Picarella G, De Campora E: Antrochoanal polyp: analysis of 200 cases. Acta Otorhinolaryngol Ital; 2009 Feb;29(1):21-6
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  • Antrochoanal polyp is a benign lesion originating from the mucosa of the maxillary sinus, growing through the accessory ostium into the middle meatus and, thereafter, protruding posteriorly to the choana and nasopharynx.
  • Whether the antrochoanal polyp is a benign tumour or not?

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  • (PMID = 19609378.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2689564
  • [Keywords] NOTNLM ; Accessory ostium / Antral cyst / Antrochoanal polyp / Maxillary ostium obstruction
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17. Lips C, Lentjes E, Höppener J, Luijt Rv, Moll F: Familial paragangliomas. Hered Cancer Clin Pract; 2006;4(4):169-76
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  • They are usually benign and have a low mortality.
  • Genetic predisposition can occur within the familial tumour syndromes multiple endocrine neoplasia type 2 (MEN 2), von Hippel-Lindau (VHL) and neurofibromatosis type 1 (NF-1), or be due to mutations in genes specific to the development of paraganglioma only.
  • Tumours should be diagnosed and resected as early as possible, as it has been shown that morbidity is related to tumour size.

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  • (PMID = 20223020.001).
  • [ISSN] 1897-4287
  • [Journal-full-title] Hereditary cancer in clinical practice
  • [ISO-abbreviation] Hered Cancer Clin Pract
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC2837305
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18. Shah N, Tighe JV, Barrett AW, Kumar S, Allen JP: Bilateral intraparotid and extraparotid Warthin's tumours. Br J Oral Maxillofac Surg; 2007 Apr;45(3):238-9
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  • Warthin's tumour is a benign adenoma in the parotid gland, but extraparotid and synchronous bilateral Warthin's tumours may occur.
  • In this report, we describe a patient with simultaneous bilateral involvement of the parotid glands and neck by multiple Warthin's tumours, an occurrence not previously described.
  • [MeSH-major] Adenolymphoma / diagnosis. Head and Neck Neoplasms / diagnosis. Parotid Neoplasms / diagnosis

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  • (PMID = 16207506.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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19. Debnath SC, Adhyapok AK: Pleomorphic adenoma (benign mixed tumour) of the minor salivary glands of the upper lip. J Maxillofac Oral Surg; 2010 Jun;9(2):205-8
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  • [Title] Pleomorphic adenoma (benign mixed tumour) of the minor salivary glands of the upper lip.
  • Pleomorphic adenoma is the benign tumor of salivary glands, which originates from the myoepithelial cells and intercalated duct cells.
  • This tumor is more common in major salivary glands.
  • The tumor was a circumscribed, submucosal nodule, about 2.0 cm in diameter and was characterized by slow growth and rubbery consistency.
  • Complete excision was performed and the histopathological analysis showed an epithelial salivary gland tumor with islands of plasmacytoid cells, duct like structures, in a variable stroma with chondroid, fibrous and myxoid appearance.

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  • (PMID = 22190789.001).
  • [ISSN] 0974-942X
  • [Journal-full-title] Journal of maxillofacial and oral surgery
  • [ISO-abbreviation] J Maxillofac Oral Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3244097
  • [Keywords] NOTNLM ; Minor salivary glands / Pleomorphic adenoma / Upper lip
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20. de Ru JA, van Benthem PP, Bleys RL, Hordijk GJ: Prevention of Frey syndrome in parotid gland surgery. J Otolaryngol; 2007 Oct;36(5):291-5
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  • RESULTS: Eighty-one patients were operated on for a parotid gland tumour.
  • CONCLUSION: We advocate our technique in primary benign tumours.

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  • (PMID = 17963668.001).
  • [ISSN] 0707-7270
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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21. O'Sullivan PJ, Harris AC, Munk PL: Radiological features of synovial cell sarcoma. Br J Radiol; 2008 Apr;81(964):346-56
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  • Synovial cell sarcoma is an uncommon soft-tissue malignant tumour.
  • These tumours have common radiological features with a variety of both benign and malignant lesions.
  • This pictorial review aims to describe the imaging features of synovial sarcoma in a series of cases with various age ranges and tumour locations.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / therapy. Heart Neoplasms / diagnosis. Heart Neoplasms / therapy. Humans. Lower Extremity. Magnetic Resonance Imaging. Male. Middle Aged. Pericardium. Prognosis. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / therapy. Thoracic Wall. Tomography, X-Ray Computed. Upper Extremity

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  • (PMID = 18250123.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 21
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22. Fiorella R, Di Nicola V, Fiorella ML, Spinelli DA, Coppola F, Luperto P, Madami L: Major salivary gland diseases. Multicentre study. Acta Otorhinolaryngol Ital; 2005 Jun;25(3):182-90
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  • Benign tumours account for 80% of case histories with a relationship 1:4 M/F, the most frequent being pleomorphic adenoma (57.3% of cases), followed by Warthin's tumour (32.4%), this rating not having been confirmed in case histories (8-10%) in the literature.
  • Surgical treatment of benign tumours consisted, in 50% of cases, in superficial paroditectomy and in approximately 30% of total paroditectomy.
  • The lateral neck dissection most frequently carried out was of functional type in 54% and selective type in 46% with removal of levels I-III and II-IV in approximately 60% of cases.
  • When no clinically evident lymph nodes were present (NO) considering the tumour histotype, two thirds of patients underwent surgery or radiotherapy, while in the remainder the wait-and-see attitude was prefered.
  • Oncological results obtained were compared with those reported in the literature: in fact for all benign neoplasms relapse ratings are about 5%, while for malignant tumours the worst prognosis was in squamous cell carcinoma with median of 37.7 on survival and metastasis rate of 16.5%.
  • [MeSH-minor] Adult. Female. Humans. Male. Middle Aged. Neoplasm Staging. Otorhinolaryngologic Surgical Procedures. Surveys and Questionnaires

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  • (PMID = 16450775.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2639866
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23. Ghosh A, Talwar OP, Pradhan SV: Tumour and tumour-like conditions of peripheral nerve origin: ten years' experience. Kathmandu Univ Med J (KUMJ); 2010 Jan-Mar;8(29):97-101
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  • [Title] Tumour and tumour-like conditions of peripheral nerve origin: ten years' experience.
  • BACKGROUND: There are four major lesions which may arise in the peripheral nerve, namely neuroma, schwannoma, neurofibroma and malignant peripheral nerve sheath tumor.
  • OBJECTIVE: In the present study we look into the spectrum of peripheral neural tumors including their age distribution site distribution and histopathology.
  • The commonest site involved for both schwannoma and neurofibroma was scalp-face-neck followed by back.
  • CONCLUSION: The majority of the tumor are benign and the commonest benign tumor was neurofibroma of sporadic type, closely followed by schwannoma.
  • In our study the commonest site was scalp-face-neck unlike other studies.

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  • (PMID = 21209517.001).
  • [ISSN] 1812-2078
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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24. Santeusanio G, Schiaroli S, Ortenzi A, Mulè A, Perrone G, Fadda G: Solitary fibrous tumour of thyroid: report of two cases with immunohistochemical features and literature review. Head Neck Pathol; 2008 Sep;2(3):231-5
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  • [Title] Solitary fibrous tumour of thyroid: report of two cases with immunohistochemical features and literature review.
  • Solitary fibrous tumour (SFT) is a rare tumour principally found in adults in the pleural cavity.
  • Tumour cells revealed a diffuse strong positivity for CD34, CD99, bcl-2 and Vimentin, but negativity for Desmin, EMA, AE1/AE3, SMA, S-100 and CD31 antibodies.
  • The differential diagnosis of thyroid SFT includes different types of spindle cell proliferation, benign and malignant mesenchymal tumours, medullary thyroid carcinoma, fasciitis-like papillary carcinoma, and undifferentiated (anaplastic) carcinoma.
  • [MeSH-major] Solitary Fibrous Tumors / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Carcinoma / diagnosis. Carcinoma, Medullary / diagnosis. Carcinoma, Papillary / diagnosis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Mesenchymoma / diagnosis. Middle Aged

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  • (PMID = 20614321.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807559
  • [Keywords] NOTNLM ; Immunohistochemistry / Review / Solitary fibrous tumour / Thyroid
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25. Saw S, Thomas N, Gleeson MJ, Bódi I, Connor S, Hortobágyi T: Giant cell tumour and central giant cell reparative granuloma of the skull: do these represent ends of a spectrum? A case report and literature review. Pathol Oncol Res; 2009 Jun;15(2):291-5
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  • [Title] Giant cell tumour and central giant cell reparative granuloma of the skull: do these represent ends of a spectrum? A case report and literature review.
  • Giant cell tumour (GCT) of bone is an uncommon primary bone neoplasm typically occurring at the epiphyses of long bones in young adults.
  • They demonstrate benign histological features, but are locally aggressive and surgical excision is the treatment of choice.
  • We present a case of a giant cell tumour of the temporal bone which illustrates and re-emphasises this concept and review the literature on these lesions.
  • [MeSH-major] Giant Cell Tumors / pathology. Granuloma, Giant Cell / pathology. Skull Neoplasms / pathology

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  • (PMID = 19011995.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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26. Morais D, Santos J, Alonso M, Ovelar Y: [Schwannoma of the external auditory canal: an exceptional location]. Acta Otorrinolaringol Esp; 2007 Apr;58(4):169-70
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  • Solitary schwannoma is a benign, encapsulated tumour of Schwann cell origin, therefore the olfactory and optic nerves are never affected.
  • About 25%-45% of all schwannomas occur in the head and neck but schwannoma of the external auditory canal is a rare finding, and we have found only 6 previous cases reported in the literature world-wide.
  • Our patient was discovered by chance during a stapedectomy because the tumour was sited in the external auditory canal without distorting it.

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  • (PMID = 17428415.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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27. Ashraf M, Kumar P, Reza MA, Ragesh KP: Neoplastic diseases of the head & neck in children. Indian J Otolaryngol Head Neck Surg; 2006 Oct;58(4):343-6
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  • [Title] Neoplastic diseases of the head & neck in children.
  • Pediatric neoplasm is next only to trauma as the most common cause of death.
  • The cervicofacial malignancies presents a unique challenge owing to potential adverse effects of both the disease process and the treatment employed on critical developing head and neck structures.This study comprised of 106 children below 12 years age group conducted during 1999-2003 at JNMC, Aligarh.
  • Of 106 cases 70 were benign neoplasms and 36 malignant neoplasms.
  • Nasopharyngeal angiofibroma was the commonest benign tumour and lymphoma was the commonest malignant neoplasm.

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  • (PMID = 23120341.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450388
  • [Keywords] NOTNLM ; Lymphoma / Nasopharyngeal angiofibroma / Neoplasm / Rhabdomyosarcoma
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28. Oxenius I, Vacirca F: [A rare case of fibroepithelial polyp of the proximal urethra in a young woman]. Urologia; 2008 Jul-Sep;75(3):193-4
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  • Fibroepithelial polyps are benign epithelial tumours which are rare in adults.
  • We report a case of a twenty-seven-year-old woman, presenting with painless terminal gross haematuria, affected by a neoplasm located in the proximal urethra near the bladder neck.
  • Endoscopic image of the tumour and histopatological details are shown.

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  • (PMID = 21086351.001).
  • [ISSN] 0391-5603
  • [Journal-full-title] Urologia
  • [ISO-abbreviation] Urologia
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] United States
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29. Bajaj Y, Singh S, Cozens N, Sharp J: Critical clinical appraisal of the role of ultrasound guided fine needle aspiration cytology in the management of parotid tumours. J Laryngol Otol; 2005 Apr;119(4):289-92
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  • OBJECTIVE: Fine needle aspiration cytology is a well established tool for investigating many head and neck conditions.
  • RESULTS: Histological evaluation revealed 13 malignant tumours and 56 benign lesions.
  • Its enhancement of the pre-operative recognition of malignant parotid tumours may alert more stringent attention to the operative margin and hence better tumour clearance.

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  • (PMID = 15949083.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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30. Zhang G, Rodriguez X, Hussain A, Desrosiers M: Outcomes of the extended endoscopic approach for management of inverted papilloma. J Otolaryngol; 2007 Apr;36(2):83-7
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  • BACKGROUND: Inverted papilloma (IP) is a benign tumour involving the paranasal sinuses.
  • The tumour is debulked, and its attachment points are identified.

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  • (PMID = 17459277.001).
  • [ISSN] 0381-6605
  • [Journal-full-title] The Journal of otolaryngology
  • [ISO-abbreviation] J Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
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31. Pratibha R, Ahmed S: Angiomatoid variant of fibrous histiocytoma: a case report and review of literature. Int J Paediatr Dent; 2006 Sep;16(5):363-9
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  • Fibrous histiocytomas by themselves are not very common in the head and neck region.
  • Apart from considering the above fact, this report describes a unique and relatively rare variant of the neoplasm - the angiomatoid fibrous histiocytoma (AFH) which has a characteristic appearance and predilection for young individuals that occurred in the left lower border of the mandible in a 13-year-old girl.
  • Angiomatoid fibrous histiocytoma is a distinct fibrohistiocytic tumour of children and young adults that combines features of both fibrohistiocytic and vascular neoplasm.
  • It is considered to be a tumour of intermediate malignancy because of its less aggressive course in contrast to the conventional malignant fibrous histiocytoma.
  • The authors would like to stress upon the fact that clinicians should not overlook swellings that may not appear distinct visually and therefore consider it to be a part of normal anatomy, dismiss it as an anomaly with no significance, or treat it injudiciously, for ultimately it may prove to be a tumour that would require appropriate treatment and follow-up.

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  • (PMID = 16879335.001).
  • [ISSN] 0960-7439
  • [Journal-full-title] International journal of paediatric dentistry
  • [ISO-abbreviation] Int J Paediatr Dent
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 35
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32. Glynn F, Keogh IJ, Ali TA, Timon CI, Donnelly M: Routine nasopharyngeal biopsy in adults presenting with isolated serous otitis media: is it justified? J Laryngol Otol; 2006 Jun;120(6):439-41
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  • Nasopharyngeal malignancy accounts for less than 2 per cent of all head and neck cancers.
  • All other patients with masses were found to have benign lymphoid hyperplasia.
  • We would advocate a high index of suspicion of a nasopharyngeal tumour in adults presenting with SOM.

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  • (PMID = 16772052.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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33. Torres-Eguía RJ, Colmenero Rolón CA, Arauz De Robles S, Guillen García P: Epiphyseal femoral tumour resection under intraosseous endoscopic control. Hip Int; 2010;20 Suppl 7:S32-5
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  • [Title] Epiphyseal femoral tumour resection under intraosseous endoscopic control.
  • We have resected 4 benign cystic femoral head tumours under intraosseous endoscopic control.
  • The resections were completely extraarticular through a tunnel made in the femoral neck from the lateral cortex.

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  • (PMID = 20512769.001).
  • [ISSN] 1724-6067
  • [Journal-full-title] Hip international : the journal of clinical and experimental research on hip pathology and therapy
  • [ISO-abbreviation] Hip Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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34. Ahmad F, Waqar-uddin, Khan MY, Khawar A, Bangush W, Aslam J: Management of parapharyngeal space tumours. J Coll Physicians Surg Pak; 2006 Jan;16(1):7-10
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  • The most common clinical features were neck mass (93%) and bulge in lateral pharyngeal wall (80%).
  • The CT scan showed exact location and extent of tumour in 11 out of 15 cases.
  • CONCLUSION: This study indicates that PPS tumours are usually benign neurogenous and salivary gland tumours presenting with neck mass and bulge in oropharynx.

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  • (PMID = 16441979.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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35. Targa-Stramandinoli R, Torres-Pereira C, Piazzetta CM, Giovanini AF, Amenábar JM: [Minor salivary gland tumours: a 10-year study]. Acta Otorrinolaringol Esp; 2009 May-Jun;60(3):199-201
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  • Salivary gland tumours represent between 2 % and 6.5 %, approximately, of all head and neck tumours.
  • Fourteen cases of salivary gland tumours were found, of which 7 were benign and 7 malignant.
  • These findings suggest that salivary gland tumours have a low incidence in the population and that the pleomorphic adenoma is the most common type of tumour, followed by mucoepidermoid carcinoma.

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  • (PMID = 19558907.001).
  • [ISSN] 0001-6519
  • [Journal-full-title] Acta otorrinolaringológica española
  • [ISO-abbreviation] Acta Otorrinolaringol Esp
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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36. de Ru JA, van Benthem PP, Hordijk GJ: Morbidity of parotid gland surgery: results 1 year post-operative. Eur Arch Otorhinolaryngol; 2006 Jun;263(6):582-5
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  • Nowadays, major complications such as recurrence of tumour and permanent facial nerve paresis are rare after primary surgery.
  • Among those with primary benign tumours, we found no recurrences and no permanent paresis, nor did starch-iodine testing reveal any cases of Frey's syndrome.

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  • (PMID = 16506039.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
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  • [Publication-type] Journal Article
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37. Driemel O, Kraft K, Hemmer J: [DNA ploidy and proliferative activity in salivary gland tumours]. Mund Kiefer Gesichtschir; 2007 Aug;11(3):139-44
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  • All 229 benign neoplasms were diploid while 12 of 50 malignant tumours showed cell populations with aneuploid DNA content.
  • The SPF values of diploid malignancies were significantly higher if compared with pleomorphic adenomas but did not differ from that of the zystadenolymphoma (Warthin tumour) group.
  • [MeSH-major] Cell Division / genetics. DNA, Neoplasm / genetics. Ploidies. Salivary Gland Neoplasms / genetics

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  • (PMID = 17505845.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / DNA, Neoplasm
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38. Pitale A, Andrabi SI, Dolan SJ, Russell CF: Minimally invasive parathyroid exploration for solitary adenoma. Initial experience with an open, 'short incision' approach. Ulster Med J; 2008 May;77(2):115-8
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  • BACKGROUND: In the vast majority of patients with primary hyperparathyroidism (HPT) the causative pathology is a benign solitary adenoma.
  • However, in recent years new techniques have permitted accurate preoperative localisation of the single parathyroid tumour in many patients.
  • More recently we have progressed to a minimally invasive surgical approach for such individuals in whom the tumour has been localised preoperatively.
  • PATIENTS & METHODS: Between September 2004 and July 2006, 24 patients with proven HPT, underwent focused, unilateral cervical exploration through a short (2.5-3 cm) incision placed low on the appropriate side of the neck.

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  • (PMID = 18711630.001).
  • [ISSN] 0041-6193
  • [Journal-full-title] The Ulster medical journal
  • [ISO-abbreviation] Ulster Med J
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Northern Ireland
  • [Other-IDs] NLM/ PMC2516437
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39. Health Quality Ontario: Energy delivery systems for treatment of benign prostatic hyperplasia: an evidence-based analysis. Ont Health Technol Assess Ser; 2006;6(17):1-121
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  • [Title] Energy delivery systems for treatment of benign prostatic hyperplasia: an evidence-based analysis.
  • OBJECTIVE: The Ontario Health Technology Advisory Committee asked the Medical Advisory Secretariat (MAS) to conduct a health technology assessment on energy delivery systems for the treatment of benign prostatic hyperplasia (BPH).
  • CLINICAL NEED: TARGET POPULATION AND CONDITION BPH is a noncancerous enlargement of the prostate gland and the most common benign tumour in aging men. (1) It is the most common cause of lower urinary tract symptoms (LUTS) and bladder outlet obstruction (BOO) and is an important cause of diminished quality of life among aging men. (2) The primary goal in the management of BPH for most patients is a subjective improvement in urinary symptoms and quality of life.
  • Complications after TURP include hemorrhage during or after the procedure, which often necessitates blood transfusion; transurethral resection (TUR) syndrome; urinary incontinence; bladder neck stricture; and sexual dysfunction.
  • A retrospective review of 4,031 TURP procedures performed by one surgeon between 1979 and 2003 showed that the incidence of complications was 2.4% for blood transfusion, 0.3% for TUR syndrome, 1.5% for hemostatic procedures, 2.8% for bladder neck contracture, and 1% for urinary stricture.

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  • (PMID = 23074487.001).
  • [ISSN] 1915-7398
  • [Journal-full-title] Ontario health technology assessment series
  • [ISO-abbreviation] Ont Health Technol Assess Ser
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC3379165
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40. Vijayendra H, Nanjundappa, Sangeetha R: Laryngeal schwannomas-case reports with rare presentations. Indian J Otolaryngol Head Neck Surg; 2008 Jun;60(2):185-7
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  • Schwannomas also known as Neurilemmomas are benign encapsulated, slow growing perineural tumours of Neuro-ectodermal origin that arise from the sheet of schwann cells.
  • Two cases are being presented due to their rarity and in both cases the diagnosis was arrived at after the excision of the tumour.

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  • (PMID = 23120537.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450511
  • [Keywords] NOTNLM ; Indirect laryngoscopy examination / Schwannomas
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41. Sze H, Yeung MW: Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine. Hong Kong Med J; 2009 Jun;15(3):221-3
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  • [Title] Fibromatosis of the neck causing airway obstruction managed effectively with weekly low-dose methotrexate and vinblastine.
  • Fibromatosis is a rare disease with benign histology.
  • We report a case of a 40-year-old woman with fibromatosis of the neck requiring an emergency operation for acute upper airway obstruction.
  • Gross residual tumour was left behind but excellent tumour shrinkage was achieved by using weekly low-dose methotrexate and vinblastine.

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  • (PMID = 19494380.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antimetabolites, Antineoplastic; 0 / Antineoplastic Agents, Phytogenic; 5V9KLZ54CY / Vinblastine; YL5FZ2Y5U1 / Methotrexate
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42. Knight DM, Birch R, Pringle J: Benign solitary schwannomas: a review of 234 cases. J Bone Joint Surg Br; 2007 Mar;89(3):382-7
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  • [Title] Benign solitary schwannomas: a review of 234 cases.
  • We reviewed 234 benign solitary schwannomas treated between 1984 and 2004.
  • There were 170 tumours (73%) in the upper limb, of which 94 (40%) arose from the brachial plexus or other nerves within the posterior triangle of the neck.
  • There were 198 primary referrals (19 of whom had a needle biopsy in the referring unit) and in these patients the tumour was excised.

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  • (PMID = 17356155.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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43. Tse GM, Wong FC, Tsang AK, Lee CS, Lui PC, Lo AW, Law BK, Scolyer RA, Karim RZ, Putti TC: Stromal nitric oxide synthase (NOS) expression correlates with the grade of mammary phyllodes tumour. J Clin Pathol; 2005 Jun;58(6):600-4
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  • [Title] Stromal nitric oxide synthase (NOS) expression correlates with the grade of mammary phyllodes tumour.
  • BACKGROUND: Nitric oxide synthase (NOS), particularly endothelial and inducible forms (e/i-NOS), are expressed in various cancers, including breast cancer.
  • In mammary fibroepithelial lesions, NOS expression in stromal cells has been reported to be lower in fibroadenomas than in phyllodes tumours.
  • AIMS: To investigate NOS expression in phyllodes tumours of varying degrees of malignancy.
  • METHODS: One hundred and sixty seven mammary phyllodes tumours (97 benign, 47 borderline malignant, and 23 frankly malignant) were evaluated for e-NOS and i-NOS expression by immunohistochemistry.
  • RESULTS: Stromal expression of e-NOS was absent, weak, moderate, and strong in 43%, 31%, 13%, and 13% of benign tumours; 17%, 26%, 13%, and 44% of borderline malignant tumours; and 17%, 35%, 13%, and 35% of frankly malignant tumours, respectively.
  • Stromal expression of i-NOS was 77%, 18%, 4%, and 1% in benign tumours; 42%, 28%, 19%, and 11% in borderline malignant tumours; and 43%, 13%, 26%, and 18% in frankly malignant tumours, respectively.
  • Stromal expression of both i-NOS and e-NOS was significantly different between the benign and malignant (borderline and frank) groups of phyllodes tumours (p < 0.0001).
  • Furthermore, the expression of i-NOS correlated with stromal VEGF expression and microvessel density.
  • The expression of NOS in the epithelial cells was strong, and showed no differences between the different groups of tumours.
  • CONCLUSIONS: Higher stromal expression of NOS in phyllodes tumours is associated with malignancy, suggesting a possible role in malignant progression, particularly metastasising potential.
  • [MeSH-major] Breast Neoplasms / enzymology. Nitric Oxide Synthase / metabolism. Phyllodes Tumor / enzymology

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  • (PMID = 15917410.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Vascular Endothelial Growth Factor A; EC 1.14.13.39 / NOS2 protein, human; EC 1.14.13.39 / NOS3 protein, human; EC 1.14.13.39 / Nitric Oxide Synthase; EC 1.14.13.39 / Nitric Oxide Synthase Type II; EC 1.14.13.39 / Nitric Oxide Synthase Type III
  • [Other-IDs] NLM/ PMC1770683
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44. Schache AG, Hall G, Woolgar JA, Nikolaidis G, Triantafyllou A, Lowe D, Risk JM, Shaw RJ, Liloglou T: Quantitative promoter methylation differentiates carcinoma ex pleomorphic adenoma from pleomorphic salivary adenoma. Br J Cancer; 2010 Dec 7;103(12):1846-51
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  • BACKGROUND: potential epigenetic biomarkers for malignant transformation to carcinoma ex pleomorphic adenoma (Ca ex PSA) have been sought previously with and without specific comparison with the benign variant, pleomorphic salivary adenoma (PSA).
  • We sought to demonstrate quantitative promoter methylation across a panel of tumour suppressor genes (TSGs) in both Ca ex PSA and PSA.
  • METHODS: quantitative methylation-specific real-time polymerase chain reaction (qMSP) analysis of p16(INK4A), CYGB, RASSF1, RARβ, human telomerase reverse transcriptase (hTERT), Wilms' tumour 1 (WT1) and TMEFF2 gene promoters was undertaken on bisulphite-converted DNA, previously extracted from archival fixed tissue specimens of 31 Ca ex PSA and an unrelated cohort of 28 PSA.
  • All target regions examined had formerly been shown to be hypermethylated in salivary and/or mucosal head and neck malignancies.
  • CONCLUSIONS: we demonstrate the successful application of qMSP to a large series of historical Ca ex PSA samples and report on a panel of TSGs with significant differences in their methylation profiles between benign and malignant variants of pleomorphic salivary adenoma. qMSP analysis could be developed as a useful clinical tool to differentiate between Ca ex PSA and its benign precursor.
  • [MeSH-minor] Genes, Tumor Suppressor. Humans. Membrane Proteins / genetics. Neoplasm Proteins / genetics. Polymerase Chain Reaction. Telomerase / genetics. WT1 Proteins / genetics

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  • [Copyright] 2010 Cancer Resaerch UK.
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  • (PMID = 21063414.001).
  • [ISSN] 1532-1827
  • [Journal-full-title] British journal of cancer
  • [ISO-abbreviation] Br. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Membrane Proteins; 0 / Neoplasm Proteins; 0 / TMEFF2 protein, human; 0 / WT1 Proteins; EC 2.7.7.49 / TERT protein, human; EC 2.7.7.49 / Telomerase
  • [Other-IDs] NLM/ PMC3008600
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45. Darling MR, Tsai S, Jackson-Boeters L, Daley TD, Diamandis EP: Human kallikrein 8 expression in salivary gland tumors. Head Neck Pathol; 2008 Sep;2(3):169-74
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  • [Title] Human kallikrein 8 expression in salivary gland tumors.
  • The aim of this study was to determine whether KLK8 is expressed in salivary gland tissues and salivary gland tumors (both benign and malignant), in order to compare normal with tumor tissues.
  • Pleomorphic adenomas, adenoid cystic carcinomas, polymorphous low grade adenocarcinomas, acinic cell carcinomas, mucoepidermoid carcinomas, and adenocarcinomas NOS of both minor and major salivary glands were examined.
  • The results of this study indicate that most salivary gland tumors show high levels of expression of KLK8.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Carcinoma, Acinar Cell / metabolism. Carcinoma, Acinar Cell / pathology. Carcinoma, Adenoid Cystic / metabolism. Carcinoma, Adenoid Cystic / pathology. Humans. Immunoenzyme Techniques

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  • (PMID = 20614312.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.21.- / KLK8 protein, human; EC 3.4.21.- / Kallikreins
  • [Other-IDs] NLM/ PMC2807567
  • [Keywords] NOTNLM ; Human kallikrein 8 / Immunohistochemistry / Kallikreins / Prognostic markers / Salivary gland tumors
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46. Bakshi J, Parida PK: Syringocystadenoma papilliferum: report of first case on the pinna. J Laryngol Otol; 2006 Dec;120(12):e45
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  • Syringocystadenoma papilliferum is a benign adnexal skin tumour, which, in a third of cases, arises from an organoid nevus on the head and neck.

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  • (PMID = 17105677.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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47. Adeyemi BF, Ogun GO, Akang EE: Retrospective analysis of intra-oral salivary gland tumours in Ibadan, Nigeria. West Afr J Med; 2010 Mar-Apr;29(2):98-103
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  • Information obtained about each patient included age, sex, tumour location and histological classification based on the 1991 WHO recommendations.
  • RESULTS: Of a total of 309 neoplasms of salivary gland origin, 92 were from the intra-oral minor salivary glands constituting 4.5% of head and neck neoplasm.
  • Fifty-seven (62%) cases were malignant, while 35 (38%) were benign.
  • The most frequently diagnosed tumour was adenoid cystic carcinoma 35(38%), followed by pleomorphic adenoma 30(32.6%).
  • Patients with malignant neoplasms were about 10 years older than those with benign tumours (p=0.012).

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  • (PMID = 20544634.001).
  • [ISSN] 0189-160X
  • [Journal-full-title] West African journal of medicine
  • [ISO-abbreviation] West Afr J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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48. Kaushik V, Bhalla RK, Nicholson C, de Carpentier JP: The chondroid syringoma: report of a case arising from the external auditory canal. Eur Arch Otorhinolaryngol; 2005 Oct;262(10):868-70
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  • Chondroid syringoma is an uncommon, benign skin adnexal tumour.

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  • (PMID = 15739085.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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49. Agrawal A, Kumar A, Sinha AK, Kumar B, Sabira KC: Chondroid syringoma. Singapore Med J; 2008 Feb;49(2):e33-4
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  • Pleomorphic adenoma, or chondroid syringoma (CS), is a rare, benign, skin appendageal tumour.
  • Because of the unremarkable clinical presentation of this rare tumour, the diagnosis is made on microscopic examination.
  • The usual presentation is of an asymptomatic, slowly-growing mass, typically located in the head and neck region.
  • In the evaluation of a middle-aged male patient with a small cutaneous nodule in the head and neck region, chondroid syringoma should also be considered in the differential diagnosis.

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  • (PMID = 18301822.001).
  • [ISSN] 0037-5675
  • [Journal-full-title] Singapore medical journal
  • [ISO-abbreviation] Singapore Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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50. Lee TX, Packer MD, Huang J, Akhmametyeva EM, Kulp SK, Chen CS, Giovannini M, Jacob A, Welling DB, Chang LS: Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells. Eur J Cancer; 2009 Jun;45(9):1709-20
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  • [Title] Growth inhibitory and anti-tumour activities of OSU-03012, a novel PDK-1 inhibitor, on vestibular schwannoma and malignant schwannoma cells.
  • Small-molecule inhibitors of AKT signalling may have therapeutic potential in suppressing the growth of benign VS and malignant schwannomas.
  • METHOD: Primary VS and Schwann cells, human malignant schwannoma HMS-97 cells and mouse Nf2(-/-) Schwann cells and schwannoma cells were prepared to investigate the growth inhibitory and anti-tumour activities of OSU-03012, a celecoxib-derived small-molecule inhibitor of phosphoinositide-dependent kinase-1.
  • The anti-tumour activity correlated with reduced AKT phosphorylation.

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  • (PMID = 19359162.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / DC005985-04; United States / NIDCD NIH HHS / DC / R01 DC005985; United States / NIDCD NIH HHS / DC / R01 DC005985-04
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / OSU 03012; 0 / Protein Kinase Inhibitors; 0 / Pyrazoles; 0 / Sulfonamides; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.2 / pyruvate dehydrogenase (acetyl-transferring) kinase
  • [Other-IDs] NLM/ NIHMS103963; NLM/ PMC2692816
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51. Sato T, Kawabata Y, Kobayashi Y, Suenaga S, Indo H, Kawano K, Iwashita Y, Morita Y, Majima HJ: Scintigraphy for interpretation of malignant tumours of the head and neck: comparison of technetium-99m-hexakis-2-methoxyisobutylisonitrile (Tc-MIBI) and thallium-201-chloride (Tl-201). Dentomaxillofac Radiol; 2005 Sep;34(5):268-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Scintigraphy for interpretation of malignant tumours of the head and neck: comparison of technetium-99m-hexakis-2-methoxyisobutylisonitrile (Tc-MIBI) and thallium-201-chloride (Tl-201).
  • METHODS: Dynamic and static scintigraphic imaging with 99Tc(m)-MIBI and Tl-201 were performed on patients with a variety of malignant and benign tumours.
  • Factors of the grade of the static scan, the blood flow index, the early and delayed retention indexes, and the tumour retention index were obtained from the scintigraphy.
  • In addition to these factors, the grade of tissue differentiation and tumour size were evaluated to clarify the difference between 99Tc(m)-MIBI and Tl-201 for the diagnosis of malignant tumours of the head and neck.
  • RESULTS: 99Tc(m)-MIBI accumulation depended upon the blood flow index in the early static scan, but this accumulation did not correlate with tumour size.
  • The accumulation in most subjects decreased in the delayed static scan, and the tumour retention index had a tendency to decrease with the grade of tissue differentiation.
  • Tl-201 accumulation depended upon the blood flow index in the early static scan similar to 99Tc(m)-MIBI, and the accumulation correlated with tumour size, unlike 99Tc(m)-MIBI.
  • The tumour retention index had a tendency to increase with the grade of tissue differentiation.
  • Thus, the tumour retention indexes showed opposite behaviours between 99Tc(m)-MIBI and Tl-201, but they both accurately determined tumour malignancy.
  • CONCLUSIONS: There was no major difference between 99Tc(m)-MIBI and Tl-201scintigraphy with respect to accuracy of diagnosis of malignant tumours of the head and neck.
  • [MeSH-major] Carcinoma, Squamous Cell / radionuclide imaging. Head and Neck Neoplasms / radionuclide imaging. Radiopharmaceuticals. Technetium Tc 99m Sestamibi. Thallium Radioisotopes

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  • (PMID = 16120875.001).
  • [ISSN] 0250-832X
  • [Journal-full-title] Dento maxillo facial radiology
  • [ISO-abbreviation] Dentomaxillofac Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0 / Thallium Radioisotopes; 7791-12-0 / thallium chloride; 971Z4W1S09 / Technetium Tc 99m Sestamibi; AD84R52XLF / Thallium
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52. Atespare A, Keskin G, Erçin C, Keskin S, Camcioglu A: Actinomycosis of the tongue: a diagnostic dilemma. J Laryngol Otol; 2006 Aug;120(8):681-3
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  • A mass that may mimic both benign and malignant neoplasms can be seen at clinical presentation and may mislead the diagnosis.
  • We report a patient who presented with a tumour-like tongue mass causing speech disturbance, diagnosed as actinomycosis.

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  • (PMID = 16716241.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents; 74469-00-4 / Amoxicillin-Potassium Clavulanate Combination
  • [Number-of-references] 13
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53. De Medts J, Dick C, Casselman J, Van Den Berghe I: Intraoral multifocal adult rhabdomyoma: a case report. B-ENT; 2007;3(4):205-8
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  • Adult rhabdomyomas are rare, benign striated-muscle neoplasms that occur in the head and neck region.
  • Radiological investigation showed the multilobulated aspect of the lesion, and an incisional biopsy of the submandibular tumour led to the diagnosis of adult-type rhabdomyoma.

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  • (PMID = 18265727.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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54. Sinha BK, Thapa N, Banskota DK: Lipoblastoma in head and neck--a rare childhood tumour. Kathmandu Univ Med J (KUMJ); 2006 Jan-Mar;4(1):94-7
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  • [Title] Lipoblastoma in head and neck--a rare childhood tumour.
  • Lipoblastoma is an uncommon benign mesenchymal tumour that occurs primarily in children younger than 3 yrs of age.
  • Despite the lesions being benign, great difficulty can be encountered in its management because of its tendency to invade the different fascial planes.
  • This huge tumour was completely and successfully removed through cheek incision without any postoperative complications.
  • [MeSH-major] Head and Neck Neoplasms / surgery. Lipoma / surgery

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  • (PMID = 18603878.001).
  • [ISSN] 1812-2027
  • [Journal-full-title] Kathmandu University medical journal (KUMJ)
  • [ISO-abbreviation] Kathmandu Univ Med J (KUMJ)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
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55. Suen DT, Chow TL, Lam CY, Wong ES, Lam SH: Sensation recovery improved by great auricular nerve preservation in parotidectomy: a prospective double-blind study. ANZ J Surg; 2007 May;77(5):374-6
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  • METHODS: Patients undergoing superficial or total conservative parotidectomy for benign tumours were recruited consecutively from November 1998 to September 2001.
  • There was no difference in sex distribution, type of operation and pathology of parotid tumour between the two groups.
  • CONCLUSION: Great auricular nerve preservation minimizes the postoperative sensory disturbance and should be considered whenever tumour clearance is not compromised.

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  • (PMID = 17497980.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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56. Hussein MR, Elsers DA, Fadel SA, Omar AE: Immunohistological characterisation of tumour infiltrating lymphocytes in melanocytic skin lesions. J Clin Pathol; 2006 Mar;59(3):316-24
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  • [Title] Immunohistological characterisation of tumour infiltrating lymphocytes in melanocytic skin lesions.
  • BACKGROUND: Although the presence of tumour infiltrating lymphocytes (TIL) is a constant feature in melanomas, their immunophenotypic characterisation is still incomplete.
  • We hypothesise that the transition from normal skin to benign naevi (BN) to melanocytic dysplastic naevi (MDN) to radial growth phase cutaneous malignant melanoma (RGP-CMM) to vertical growth phase cutaneous malignant melanoma (VGP-CMM) is associated with alterations in TIL.
  • CONCLUSIONS: The gradual increase in TIL during melanoma tumorigenesis may reflect increased antigenicity of the tumour cells.
  • [MeSH-major] Biomarkers, Tumor / analysis. Lymphocytes, Tumor-Infiltrating / pathology. Melanocytes / pathology. Melanoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Analysis of Variance. Antigens, CD20 / analysis. Antigens, CD3 / analysis. Antigens, CD45 / analysis. Case-Control Studies. Disease Progression. Humans. Immunohistochemistry / methods. Immunophenotyping. Lymphocyte Count. Neoplasm Staging. Nevus / immunology. Nevus / pathology. T-Lymphocytes, Cytotoxic / pathology

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  • (PMID = 16505286.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD3; 0 / Biomarkers, Tumor; EC 3.1.3.48 / Antigens, CD45
  • [Other-IDs] NLM/ PMC1860334
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57. Bozza F, Vigili MG, Ruscito P, Marzetti A, Marzetti F: Surgical management of parapharyngeal space tumours: results of 10-year follow-up. Acta Otorhinolaryngol Ital; 2009 Feb;29(1):10-5
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  • Although primary tumours of the parapharyngeal space are rare and account for only 0.5% of head and neck neoplasms, they represent a formidable challenge to the surgeon both in the assessment of the preoperative condition and the appropriate surgical approach.
  • Of these, 8 (66.6%) were benign and 4 (33.4%) malignant.
  • The positive predictive value of our fine-needle aspiration biopsy was 75% for benign tumours (3/4) and 100% (4/4) for malignant tumours.
  • These 12 parapharyngeal space tumours were treated with use of one of the various surgical approaches described in relation to the histopathological diagnosis (benign or malignant), to the side (prestyloid or poststyloid) and to the size (+/-4 cm) of the neoplasia and, moreover, were observed at long-term follow-up.
  • [MeSH-major] Head and Neck Neoplasms / surgery

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  • (PMID = 19609376.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2689563
  • [Keywords] NOTNLM ; Mandibulotomy / Parapharyngeal space / Parapharyngeal tumour / Parotid / Pleomorphic adenoma / Surgical approach
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58. Sajid MS, Hamilton G, Baker DM, Joint Vascular Research Group: A multicenter review of carotid body tumour management. Eur J Vasc Endovasc Surg; 2007 Aug;34(2):127-30
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  • [Title] A multicenter review of carotid body tumour management.
  • OBJECTIVE: Carotid body tumour (CBT) is a rare but the most common form of head and neck paraganglioma (PGL).
  • Generic terms including carotid body tumour/s, or paraganglioma/s were used to search a variety of electronic database in order to get latest informations available in literature.
  • Neck lump (98%) and pressure symptoms including cranial nerve deficits and pain were main presenting complaints.
  • Mostly CBT is benign but malignant forms are not uncommon.
  • [MeSH-major] Carotid Body Tumor / surgery. Head and Neck Neoplasms / surgery. Vascular Surgical Procedures

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  • (PMID = 17400487.001).
  • [ISSN] 1078-5884
  • [Journal-full-title] European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
  • [ISO-abbreviation] Eur J Vasc Endovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
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59. Brazão-Silva MT, Fernandes AV, Durighetto-Júnior AF, Cardoso SV, Loyola AM: Central odontogenic fibroma: a case report with long-term follow-up. Head Face Med; 2010;6:20
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  • An osteolytic tumour of the mandible with prominent expansive growth on the alveolar ridge and displacement of the involved teeth is described in a 28-year-old man.
  • The lesion was diagnosed as a central odontogenic fibroma, an uncommon benign neoplasm derived from dental apparatus, and was removed by curettage.
  • [MeSH-major] Fibroma / surgery. Gingival Neoplasms / surgery. Odontogenic Tumors / surgery

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  • (PMID = 20707924.001).
  • [ISSN] 1746-160X
  • [Journal-full-title] Head & face medicine
  • [ISO-abbreviation] Head Face Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2927520
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60. Basu D, Sengupta A, Adhikari D, Dam A, Anwar T: Granular cell myoblastoma of the tongue in a 2-year-old girl: a case report. J Indian Med Assoc; 2010 Mar;108(3):170, 175
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  • Granular cell tumours are uncommon lesions, although the head and neck region accounts for approximately 50% of all lesions.
  • It is not clear whether or not granular cell tumour is a true neoplasm, a developmental anomaly, or a trauma-induced proliferation.
  • The other head and neck site likely to be involved is the larynx.
  • The tumour generally occurs in middle or older aged adults.
  • As most of the granular cell tumours are benign, surgical excision of the lesion is the treatment of choice.
  • [MeSH-major] Granular Cell Tumor / pathology. Tongue Neoplasms / pathology

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  • (PMID = 21043356.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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61. Smehák G, Rovó L, Tiszlavicz L, Jóri J: Perineurioma originating from the recurrent laryngeal nerve, and the phonochirurgical treatment of the developed vocal fold palsy. Eur Arch Otorhinolaryngol; 2008 Feb;265(2):237-41
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  • Perineurioma is a rare, benign tumour of the perineurium, which develops mostly on the nerves of the extremities.
  • The neoplasm related to a genetic mutation on the 22nd chromosome, is a rarity on the vagal nerve branches.
  • After the removal of the tumour together with the involved 2-cm-long part of the nerve, vocal fold palsy developed with aphonia (left vocal fold was in intermedian position).

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  • (PMID = 17687560.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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62. Jensen SG, Krogdahl A, Godballe C: [Aggressive fibromatosis of the frontal sinus]. Ugeskr Laeger; 2009 Jan 26;171(5):324-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Aggressive fibromatosis (AF) is a benign tumour with expansive and locally invasive growth.
  • It is very rarely seen in the head and neck area.
  • The condition was initially mistaken for chronic sinusitis however computed tomography indicated tumour.


63. Lukes P, Pácová H, Kucera T, Veselý D, Martínek J, Astl J: Expression of endothelial and inducible nitric oxide synthase and caspase-3 in tonsillar cancer, chronic tonsillitis and healthy tonsils. Folia Biol (Praha); 2008;54(5):141-5
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  • NO, synthesized by NOS, plays an important role in tumour growth, dissemination and vascularization.
  • The differences in localization of eNOS and caspase-3 expression between benign and malignant processes may be a promising tool for precise morphological distinction of chronic inflammation and tumours.

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  • (PMID = 19178812.001).
  • [ISSN] 0015-5500
  • [Journal-full-title] Folia biologica
  • [ISO-abbreviation] Folia Biol. (Praha)
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Cytokines; EC 1.14.13.39 / NOS2 protein, human; EC 1.14.13.39 / NOS3 protein, human; EC 1.14.13.39 / Nitric Oxide Synthase Type II; EC 1.14.13.39 / Nitric Oxide Synthase Type III; EC 3.4.22.- / Caspase 3
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64. Trivedi A, Patel J: A rare case of inflammatory pseudotumour of the submandibular lymphnode. Indian J Otolaryngol Head Neck Surg; 2006 Oct;58(4):408-9
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  • Inflammatory pseudotumour (IPT), also known as inflammatory myofibroblastic tumour, is a rare cause of benign cervical lymphadenopathy.
  • Radical surgery should be avoided before there is histological proof of a malignant tumor.

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  • [Cites] Otolaryngol Head Neck Surg. 1993 Sep;109(3 Pt 1):548-51 [8414578.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2003 Jun;67(6):649-53 [12745159.001]
  • [Cites] AJNR Am J Neuroradiol. 2001 Aug;22(7):1394-7 [11498435.001]
  • (PMID = 23120369.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450364
  • [Keywords] NOTNLM ; Inflammatory pseudotumour / radio-patho findings / steroids / submandibular lymphnode
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65. Grant DG, Breitenfeldt N, Shepherd NA, Thomas DM: Intranodal neurilemmoma presenting as parotid mass. J Laryngol Otol; 2009 Aug;123(8):912-4
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  • OBJECTIVE: We report a case of benign intranodal neurilemmoma, an extremely rare tumour arising from a nerve sheath within a lymph node.
  • Histopathological analysis revealed a tumour arising from a lymph node within the superficial lobe of the parotid gland.
  • The tumour demonstrated histological features of an intranodal neurilemmoma.

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  • (PMID = 18940018.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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66. Lillo FB: Human papillomavirus infection and its role in the genesis of dysplastic and neoplastic lesions of the squamous epithelia. New Microbiol; 2005 Apr;28(2):111-8
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  • Extensive laboratory and epidemiological evidence demonstrate that human papillomavirus (HPV) is the major cause of squamous cervical carcinoma (SCC), its precursor lesions (cervical intraepithelial neoplasia - CIN) and several other benign and malign clinical manifestations including genital warts, condylomata acuminata, Bowenoid papulosis, vaginal, vulvar and anal intraepithelial neoplasia (VIN and AIN) and carcinoma, penile carcinoma and other squamous neoplasias of the head and neck districts.
  • The relevance and high level of scientific interest surrounding HPVs are related to the oncogenic potential of some viral types belonging to this family and the possibility to influence the incidence of various tumour forms likecervical carcinoma, improving the efficacy of specific screening programs or defining preventive strategies like vaccination.
  • [MeSH-major] Carcinoma, Squamous Cell. Cervical Intraepithelial Neoplasia. Papillomaviridae / pathogenicity. Papillomavirus Infections / virology

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  • (PMID = 16035255.001).
  • [ISSN] 1121-7138
  • [Journal-full-title] The new microbiologica
  • [ISO-abbreviation] New Microbiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 40
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67. Hassan S, Abdullah J, Abdullah B, Jihan Wd S, Jaafar H, Abdullah S: Appraisal of clinical profile and management of juvenile nasopharyngeal angiofibroma in malaysia. Malays J Med Sci; 2007 Jan;14(1):18-22
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  • Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally invasive tumour.

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  • [Cites] J Laryngol Otol. 2000 Sep;114(9):727-30 [11091844.001]
  • [Cites] Laryngoscope. 2002 Jul;112(7 Pt 1):1213-20 [12169902.001]
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  • (PMID = 22593647.001).
  • [ISSN] 1394-195X
  • [Journal-full-title] The Malaysian journal of medical sciences : MJMS
  • [ISO-abbreviation] Malays J Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
  • [Other-IDs] NLM/ PMC3351213
  • [Keywords] NOTNLM ; Juvenile nasopharyngeal angiofibroma / clinical profile / diagnosis / maxillary swing / surgical options
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68. Bayindir T, Kalcioglu MT, Kizilay A, Karadag N, Akarcay M: Ancient schwannoma of the parotid gland: a case report and review of the literature. J Craniomaxillofac Surg; 2006 Jan;34(1):38-42
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  • Schwannomas are encapsulated benign tumours arising from nerve sheath cells, of which ancient schwannoma is one of five variants.
  • Since the first description, only a few ancient schwannomas have been reported in different locations in the head and neck region.
  • In the parotid gland, this tumour is very rare.

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  • (PMID = 16343919.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 30
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69. Erkan AN, Bal N, Kiroglu E: A case report of hemangioendothelioma of the hard palate. B-ENT; 2008;4(3):175-8
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  • Hemangioendothelioma is a rare vascular tumour with potential for malignancy that is intermediate between that of a benign hemangioma and a malignant angiosarcoma.
  • This tumour occurs infrequently in the head and neck regions.

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  • (PMID = 18949965.001).
  • [ISSN] 1781-782X
  • [Journal-full-title] B-ENT
  • [ISO-abbreviation] B-ENT
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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70. Daniels JS: Granular cell tumour of tongue: A case report. Saudi Dent J; 2009 Jul;21(2):75-8
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  • [Title] Granular cell tumour of tongue: A case report.
  • Granular cell tumour, also known as Abrikossoff tumour, is a relatively uncommon benign neoplasm, which is more commonly found in females in the 4th to 6th decades of life even though it can occur in all ages.
  • It occurs in all areas of the body but about 45-65% of all lesions are reported in the head and neck region.
  • Intraoral lesions represent about 70% of the granular cell tumours of the head and neck, and account for 1/3 of all cases affecting the whole body.
  • Although majority of granular cell tumours are benign, some are clinically aggressive and a few frankly malignant forms have been reported.
  • Some benign lesions exhibit surface ulcerations and this clinical appearance, combined with the overlying pseudoepitheliomatous hyperplasia, seen histologically, may lead to misdiagnosis of malignancy if adequate biopsy material was not taken.
  • A case of granular cell tumour which occurred on the midline area of the dorsum of the posterior 1/3 of the tongue is reported in a 20-year-old female patient.
  • It is interesting because the patient was younger than the average age of occurrence and the tumour occurred in a similar site to that of a lingual thyroid.

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  • (PMID = 23960463.001).
  • [ISSN] 1013-9052
  • [Journal-full-title] The Saudi dental journal
  • [ISO-abbreviation] Saudi Dent J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Saudi Arabia
  • [Other-IDs] NLM/ PMC3722994
  • [Keywords] NOTNLM ; Dorsum of posterior one-third of tongue / Granular cell tumour / Lingual thyroid / Pseudoepitheliomatous hyperplasia / Squamous cell carcinoma of tongue
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71. Schulten EA, Winters HA, Koch AE: [Reconstruction after surgical treatment of head and neck cancer: surgical and prosthetic possibilities]. Ned Tijdschr Tandheelkd; 2008 Apr;115(4):215-23
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  • [Title] [Reconstruction after surgical treatment of head and neck cancer: surgical and prosthetic possibilities].
  • Soft and hard tissue defects in the head and neck region after benign or malignant tumour resection, can be reconstructed by surgical techniques, such as tissue transplantation, and/or prostheses.
  • [MeSH-major] Dental Implantation, Endosseous / methods. Head and Neck Neoplasms / rehabilitation. Patient Satisfaction. Reconstructive Surgical Procedures / methods

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  • (PMID = 18512520.001).
  • [ISSN] 0028-2200
  • [Journal-full-title] Nederlands tijdschrift voor tandheelkunde
  • [ISO-abbreviation] Ned Tijdschr Tandheelkd
  • [Language] dut
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 22
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72. Mazlina S, Putra SH, Shiraz MA, Hazim MY, Roszalina R, Abdul AR: Maxillary sinus tumours--a review of twenty-nine patients treated by maxillectomy approach. Med J Malaysia; 2006 Aug;61(3):284-7
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  • Seventeen patients (59%) presented with malignant tumours while 12 patients (41%) with benign tumours.
  • Inverted papilloma (50%) was the commonest benign tumour and squamous cell carcinoma (36%) was the commonest malignancy.

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  • (PMID = 17240576.001).
  • [ISSN] 0300-5283
  • [Journal-full-title] The Medical journal of Malaysia
  • [ISO-abbreviation] Med. J. Malaysia
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Malaysia
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73. Ahmad Z, Khurshid A, Qureshi A: Primary orbital yolk sac tumour in a 14-year-old girl. BMJ Case Rep; 2009;2009
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  • [Title] Primary orbital yolk sac tumour in a 14-year-old girl.
  • Yolk sac tumour is a common malignant germ cell tumour, which usually occurs in the testes or ovaries of infants.
  • Extragonadal germ cell tumours of the head and neck region account for 5% of all benign and malignant germ cell tumours.
  • The orbit is an extremely unusual location for development of primary yolk sac tumour.
  • The present report concerns the case of a yolk sac tumour in a 14-year-old girl, arising as a primary tumour of the orbit with invasion of periorbital and intracranial spaces.

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  • (PMID = 22096462.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027343
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74. Linecker A, Kermer C, Sulzbacher I, Angelberger P, Kletter K, Dudczak R, Ewers R, Becherer A: Uptake of (18)F-FLT and (18)F-FDG in primary head and neck cancer correlates with survival. Nuklearmedizin; 2008;47(2):80-5; quiz N12
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  • [Title] Uptake of (18)F-FLT and (18)F-FDG in primary head and neck cancer correlates with survival.
  • The aim of the study was to determine the practicability of (18)F-FLT in tumours of the head and neck area in terms of visualization, a possible correlation between FLT uptake and proliferation fraction as determined by Ki-67 immunostaining, and if tumoural FLT-uptake has a prognostic meaning, as determined by a correlation to patient survival time.
  • PATIENTS, METHODS: 20 patients with previously untreated lesions of the head and neck area, which were clinically highly suspicious to be malignant, underwent PET scans with (18)F-FLT and (18)F-FDG, a CT of the head and neck area, and a biopsy.
  • Tumour tracer uptake was determined by standardized uptake value (SUV) normalized to body weight and /non-tumor ratios (T/N). (18)F-FDG and (18)F-FLT uptake were compared with histopathologic and immunohistochemical results.
  • RESULTS: 19 patients had malignant tumours; one patient had a benign cystadenoma (so called Warthin's tumour) of the parotid gland.
  • One negative lesion turned out to be a malignant T1 stage squamous cell carcinoma in both PET scans, the Warthin's tumour was false positive with (18)F-FDG but showed only faint uptake with (18)F-FLT, resulting in a sensitivity of 95 % for both tracers.
  • CONCLUSION: In head and neck cancer in the primary setting (18)F-FLT does not provide additional visual information in comparison to (18)F-FDG.(18)F-FLT uptake is inversely correlated with patient survival, as well as (18)F-FDG.
  • [MeSH-major] Dideoxynucleosides. Fluorodeoxyglucose F18 / pharmacokinetics. Head and Neck Neoplasms / mortality. Head and Neck Neoplasms / radionuclide imaging. Radioisotopes

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  • (PMID = 18392317.001).
  • [ISSN] 0029-5566
  • [Journal-full-title] Nuklearmedizin. Nuclear medicine
  • [ISO-abbreviation] Nuklearmedizin
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Dideoxynucleosides; 0 / Fluorine Radioisotopes; 0 / Radioisotopes; 0Z5B2CJX4D / Fluorodeoxyglucose F18; PG53R0DWDQ / alovudine
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75. Heal C, Buettner P, Raasch B, Browning S: Minor skin excisions in general practice in North Queensland. Aust Fam Physician; 2006 Oct;35(10):825-8
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  • Our number needed to treat (benign or dysplastic naevi excised per melanoma) was 8.4.
  • Relative tumour density was greatest in the face, scalp and neck region for all skin cancers.

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  • (PMID = 17019461.001).
  • [ISSN] 0300-8495
  • [Journal-full-title] Australian family physician
  • [ISO-abbreviation] Aust Fam Physician
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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76. Aust W, Bloching M, Holzhausen HJ, Kösling S, Knipping S: [Tuberculosis of the parotid gland]. HNO; 2008 Apr;56(4):425-8
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  • The different tumours of the parotid gland can be divided in benign or malignant tumours, regional inflammations and enlarged lymph nodes.
  • We report on a 26-year-old male from Uganda with a slowly growing tumour of the right parotid gland for several months.
  • The CT scan showed a poorly defined intraparotideal tumour.
  • Suspecting a neoplasm of the parotid gland we decided to perform a superficial parotidectomy for histological examination.

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  • [Cites] HNO. 2002 Apr;50(4):332-8 [12063691.001]
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  • (PMID = 17380314.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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77. Dellmann A, Schroeder HG, Donhuijsen K: Destructive tumours of the larynx mimicking osteosarcoma: two cases of osteoblastoma with organ-saving resection and follow-up. Eur Arch Otorhinolaryngol; 2010 Jan;267(1):151-4
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  • Osteoblastoma of the larynx is an extremely rare type of locally progressive and destructive tumour which is mimicking osteosarcoma radiologically and histologically.
  • Since prognostic and therapeutic strategies for benign osteoblastoma differ from the more common osteosarcoma of the larynx, a meticulous pre-operative histological diagnosis is required to avoid over-therapy.
  • We report about two patients with osteoblastoma of the larynx with organ-saving resection and long-period follow-up without tumour recurrence.

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  • (PMID = 19760213.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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78. Ramchandani PL, Sabesan T, Hussein K: Angiolymphoid hyperplasia with eosinophilia masquerading as Kimura disease. Br J Oral Maxillofac Surg; 2005 Jun;43(3):249-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Angiolymphoid hyperplasia with eosinophilia is a rare benign vasoproliferative disease of unknown cause, which can present as tumour-like nodules in the head and neck.

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  • (PMID = 15888362.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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79. Watkinson JC: Fifteen years' experience in thyroid surgery. Ann R Coll Surg Engl; 2010 Oct;92(7):541-7
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  • Surgery usually entails either lobectomy or total thyroidectomy, and for malignancy, patients may need a neck dissection.
  • PATIENTS AND METHODS: In the study cohort, 1113 patients had benign disease and 387 malignancy.
  • For benign disease, 716 patients had lobectomy or isthmusectomy, 44 had near-total thyroidectomy and 318 a total thyroidectomy.
  • The role of pituitary tumour transforming gene (PTTG), PTTG binding factor (PBF) and sodium iodide symporter (NIS) in thyroid cell function was then evaluated.

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  • (PMID = 20883601.001).
  • [ISSN] 1478-7083
  • [Journal-full-title] Annals of the Royal College of Surgeons of England
  • [ISO-abbreviation] Ann R Coll Surg Engl
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3229340
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80. Listewnik MH, Birkenfeld B, Chosia M, Elbl B, Niedziałkowska K, Sawrymowicz M: The occurrence of malignant thyroid lesions in patients after radioiodine treatment due to benign thyroid diseases. Endokrynol Pol; 2010 Sep-Oct;61(5):454-7
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  • [Title] The occurrence of malignant thyroid lesions in patients after radioiodine treatment due to benign thyroid diseases.
  • INTRODUCTION: Radioiodine treatment (RT) of benign thyroid diseases is a well-known, safe, and effective treatment.
  • Apart from thyroid function estimation, if needed, fine needle aspiration biopsy (FNAB) of the thyroid or neck focal lesions was performed based on ultrasonographic or clinical examination.
  • Suspicious thyroid lesion results were found in 9 patients (8 F, 1 M), aged 46-73 (average 56 years) followed up for 3-57 months after RT: papillary cancer in two patients, Hürthle cell tumour in one patient, and suspicious cells in two patients (with benign lesions on postoperative histopathology).
  • A follicular tumour in FNAB was suspected in two cases (no data about the first, and the second with lung cancer was not operable).
  • CONCLUSIONS: Malignant thyroid lesions in patients after RT due to benign thyroid diseases are seldom detected.

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  • (PMID = 21049457.001).
  • [ISSN] 0423-104X
  • [Journal-full-title] Endokrynologia Polska
  • [ISO-abbreviation] Endokrynol Pol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Iodine Radioisotopes; Thyroid cancer, Hurthle cell; Thyroid cancer, papillary
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81. Giannone N, Lo Muzio L, Politi M: Extracapsular lumpectomy and SMAS flap for benign parotid tumours: an early outcome in a small number of cases on Frey's syndrome and facial nerve dysfunction. J Craniomaxillofac Surg; 2008 Jun;36(4):239-43
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  • [Title] Extracapsular lumpectomy and SMAS flap for benign parotid tumours: an early outcome in a small number of cases on Frey's syndrome and facial nerve dysfunction.
  • Parotidectomy is the most common approach for benign salivary neoplasms.
  • The aim of the present study was to retrospectively analyse no. 34 extracapsular lumpectomies (ELs) performed with superficial musculoaponeurotic system (SMAS) flaps on 32 patients for benign parotid tumours.
  • None of the patients affected by pleomorphic adenoma or Warthin's tumour had a complete facial palsy.
  • [MeSH-minor] Adult. Aged. Connective Tissue / surgery. Facial Paralysis / etiology. Fascia / surgery. Female. Humans. Male. Middle Aged. Neck Muscles / surgery. Retrospective Studies. Sweating, Gustatory / etiology. Temporal Arteries

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  • (PMID = 18313936.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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82. Manganaris A, Tsompanidou C, Manganaris T: A peripheral nerve sheath tumour as a cause of nasal obstruction. J Laryngol Otol; 2006 Dec;120(12):e44
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  • [Title] A peripheral nerve sheath tumour as a cause of nasal obstruction.
  • Neurogenic tumours form a very small percentage of all neoplastic lesions of the head and neck region.
  • However, the head and neck region is by far the most common location for benign peripheral nerve tumours.

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  • (PMID = 17112398.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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83. Hussein MR, Elsers DA, Fadel SA, Omar AE: Clinicopathological features of melanocytic skin lesions in Egypt. Eur J Cancer Prev; 2006 Feb;15(1):64-8
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  • The lesions examined included 12 benign naevi (BN), 10 dysplastic naevi (DN), and 21 cutaneous malignant melanomas (CMMs).
  • The lower limb (13/21, 62%), head and neck (7/21, 33%) were the most common sites for CMMs.
  • The mean tumour thickness (Breslow) was 6+/-0.5 mm.
  • In Egypt, CMM is the third most common cutaneous neoplasm following squamous and basal cell carcinomas.

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  • (PMID = 16374232.001).
  • [ISSN] 0959-8278
  • [Journal-full-title] European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
  • [ISO-abbreviation] Eur. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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84. Pestoni C, Paredes-Suarez C, Peteiro C, Toribio J: Early detection of cutaneous angiosarcoma of the face and scalp and treatment with placitaxel. J Eur Acad Dermatol Venereol; 2005 May;19(3):357-9
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  • Cutaneous angiosarcoma (AS) of the face and scalp of the elderly is a rare malignant tumour with a very poor prognosis.
  • The variable presentation and the benign appearance of the cutaneous AS may often delay the correct diagnosis.
  • [MeSH-major] Antineoplastic Agents, Phytogenic / therapeutic use. Facial Neoplasms / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangiosarcoma / diagnosis. Paclitaxel / therapeutic use. Scalp. Skin Neoplasms / diagnosis

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  • (PMID = 15857466.001).
  • [ISSN] 0926-9959
  • [Journal-full-title] Journal of the European Academy of Dermatology and Venereology : JEADV
  • [ISO-abbreviation] J Eur Acad Dermatol Venereol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Phytogenic; P88XT4IS4D / Paclitaxel
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85. Wiegand S, Zimmermann AP, Eivazi B, Sesterhenn AM, Sekundo W, Bien S, Werner JA, Barth PJ: Analysis of clinically suspected orbital cavernomas. Br J Ophthalmol; 2010 Dec;94(12):1653-6
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  • BACKGROUND: Orbital cavernomas are low-flow vascular malformations that are the most common benign neoplasms of the orbit in adults, typically becoming symptomatic in the middle age.
  • Two of them were haemorrhagic lymphangiomas, and one was a solitary fibrous tumour.

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  • (PMID = 20494913.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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86. Cherif F, Dhaoui A, Kort R, Haouet S, El Euch D, Ben Osman Dhahri A: [Eccrine poroma of the scalp: A study of three cases]. Tunis Med; 2006 Jun;84(6):391-3
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  • The eccrine poroma is a rare benign sudoral tumour, which creates a fleshy formation.
  • [MeSH-major] Acrospiroma. Head and Neck Neoplasms. Scalp. Sweat Gland Neoplasms

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  • (PMID = 17042218.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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87. Li ZG, Zou SQ, Pan XY: [Calcifying epithelioma in the neck: report of one case]. Shanghai Kou Qiang Yi Xue; 2009 Dec;18(6):665-6
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  • [Title] [Calcifying epithelioma in the neck: report of one case].
  • Calcifying epithelioma is one kind of benign tumour,which rarely happens in the neck.
  • This paper reported one case of calcifying epithelioma in the neck, and discussed its clinical features and therapy based on literature review.
  • [MeSH-major] Head and Neck Neoplasms. Skin Neoplasms

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  • (PMID = 20143035.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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88. Zanoletti E, Mazzoni A, Barbò R: Pseudotumoural hypertrophic neuritis of the facial nerve. Acta Otorhinolaryngol Ital; 2008 Apr;28(2):55-60
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  • In a retrospective study of our cases of recurrent paralysis of the facial nerve of tumoural and non-tumoural origin, a tumour-like lesion of the intra-temporal course of the facial nerve, mimicking facial nerve schwannoma, was found and investigated in 4 cases.
  • The picture was one of recurrent acute facial palsy with incomplete recovery and imaging of a benign tumour.

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  • (PMID = 18669068.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
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89. Al Salamah SM, Khalid K, Khan IA, Gul R: Outcome of surgery for parotid tumours: 5-year experience of a general surgical unit in a teaching hospital. ANZ J Surg; 2005 Nov;75(11):948-52
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  • BACKGROUND: Most of the recent reports on the surgical management of parotid gland disorders come from specialist divisions of otolaryngology, head and neck, or faciomaxillary surgery.
  • Warthin's tumour was more common among male patients and was the only pathology with bilateral involvement.
  • Malignant tumour was found in five patients (13.5%).
  • There was no recurrence identified in patients with benign diseases during the mean follow up of 38.5 months.

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  • (PMID = 16336383.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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90. Peycru T, Tardat E, Schwartz A, Dufau JP, Benois A, Durand-Dastes F: Hibernoma of the neck: a rare benign tumour. Can J Surg; 2009 Jun;52(3):E52-3
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  • [Title] Hibernoma of the neck: a rare benign tumour.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Head and Neck Neoplasms / surgery. Lipoma / diagnosis. Lipoma / surgery

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  • (PMID = 19503645.001).
  • [ISSN] 1488-2310
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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91. Iacono C, Bortolasi L, Serio G: Indications and technique of central pancreatectomy-early and late results. Langenbecks Arch Surg; 2005 Jun;390(3):266-71
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  • BACKGROUND AND AIM: Central pancreatectomy (CP) is an operation that allows one to resect benign or low grade malignant tumours located in the pancreatic isthmus that are not suitable for enucleation.
  • PATIENTS AND METHODS: The operation is carried out by exposition of the pancreatic neck involved by the lesion.
  • The indications for CP were: serous cystadenoma in seven patients, mucinous in three, solid cystic papillary tumour in one, metastasis from renal cancer in one and endocrine tumour in eight patients.
  • CONCLUSION: CP is a safe technique for benign or low-grade malignant tumours of the pancreatic neck that allows one to cure the tumour with evident functional results without increasing the risk to the patient.

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  • (PMID = 15864637.001).
  • [ISSN] 1435-2443
  • [Journal-full-title] Langenbeck's archives of surgery
  • [ISO-abbreviation] Langenbecks Arch Surg
  • [Language] eng
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92. De Vincentiis M, Greco A, Mascelli A, Soldo P, Zambetti G: Lipoma of the larynx: a case report. Acta Otorhinolaryngol Ital; 2010 Feb;30(1):58-63
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  • Lipoma is a benign tumour of mesenchymal origin with a very rare occurrence in the upper aero-digestive tract.
  • It is very important to completely remove these benign neoplasms in order to avoid local recurrence.

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  • (PMID = 20559475.001).
  • [ISSN] 1827-675X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2881609
  • [Keywords] NOTNLM ; Imaging / Larynx / Lipoma / Surgical techniques
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93. Scaranelo AM, Bukhanov K, Crystal P, Mulligan AM, O'Malley FP: Granular cell tumour of the breast: MRI findings and review of the literature. Br J Radiol; 2007 Dec;80(960):970-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Granular cell tumour of the breast: MRI findings and review of the literature.
  • Granular cell tumours (GCTs) are uncommon, usually benign neoplasms that can mimic malignancy on breast imaging.
  • GCTs can originate anywhere in the body but are most frequently found in the head and neck area, particularly in the oral cavity.
  • We report a case of granular cell tumour of the breast presenting as a suspicious lesion on breast imaging, and review the MRI features of GCTs.
  • [MeSH-major] Breast Neoplasms / diagnosis. Granular Cell Tumor / diagnosis

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  • (PMID = 17940129.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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94. Oeken J, Törpel J: [The influence of navigation on endoscopic sinus surgery]. HNO; 2008 Feb;56(2):151-4, 156-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • RESULTS: Navigated ESS was carried out on 106 patients (54 male symbol; 52 female symbol, average age 55 years) with the following diagnoses: 59 chronic sinusitis with nasal polyposis (13 primary surgery, 46 revision surgery), 14 mucocele, 8 benign tumour, 10 malignant sinonasal tumour, and 15 other diseases.
  • The degree of benefit of navigation for the different diagnoses was in descending order: recurrent polyposis, mucocele, osteoma, malignant tumors, polyposis (primary surgery) and inverted papilloma.

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  • [Cites] HNO. 2003 Mar;51(3):209-15 [12627248.001]
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  • (PMID = 17520232.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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95. Kohlhof JK, Müller-Richter U, Driemel O, Sachs H: [Pleomorphic malignant fibrous histiocytoma of the periorbital region]. Klin Monbl Augenheilkd; 2007 Mar;224(3):203-6
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  • About 3 % percent of all pleomorphic malignant fibrous histiocytomas arise in the head and neck region.
  • PATIENT: A 91 year old female patient presented because of a prominent tumour in the upper right periorbital region.
  • As stated in the case history, the tumour had developed within the previous 6 months.
  • The tumour measured about 3 x 4 cm.
  • Due to the mass of the tumour a ptosis was present.
  • CLINIC: Neither CT nor MRI could give a clue to the tumour entity.
  • A biopsy was classified as a malignant fibrous tumour with the subclassification of an atypical fibroxanthoma.
  • The final histopathological classification after total excision of the tumour showed perineural growth and angioinvasion.
  • Therefore the tumour classification was changed to pleomorphic malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma).
  • Immunohistochemical stainings (Vimentin) were carried out to characterise the tumour.
  • In the process of finding the right diagnosis sometimes a change from benign to malignant occurs and alters the treatment regime.


96. Jurado-Ramos A, Ropero Romero F, Cantillo Baños E, Salas Molina J: Minimally invasive endoscopic techniques for treating large, benign processes of the nose, paranasal sinus, and pterygomaxillary and infratemporal fossae: solitary fibrous tumour. J Laryngol Otol; 2009 Apr;123(4):457-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Minimally invasive endoscopic techniques for treating large, benign processes of the nose, paranasal sinus, and pterygomaxillary and infratemporal fossae: solitary fibrous tumour.
  • The tumour was resected by means of sinonasal endoscopic surgery; an endoscopic medial maxillectomy with extension to the pterygomaxillary and infratemporal regions was performed.
  • Histological analysis confirmed the diagnosis of solitary fibrous tumour.
  • [MeSH-major] Endoscopy / methods. Nose Neoplasms / surgery. Solitary Fibrous Tumors / surgery. Temporal Bone / surgery

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  • (PMID = 18405404.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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97. Syed A, Iraqi AA, Azam Q, Ahmad S: Lipoblastoma--a rare paediatric foot tumour. Acta Orthop Belg; 2007 Jun;73(3):400-2
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  • [Title] Lipoblastoma--a rare paediatric foot tumour.
  • Lipoblastoma, a rare benign tumour arising from embryonic fat, is usually found in areas of abundant adipose tissue.
  • Various reports describe a predilection of lipoblastoma for sites with primitive adipose tissue such as axilla, neck, retroperitoneum and prevertebral soft tissue.

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  • (PMID = 17715735.001).
  • [ISSN] 0001-6462
  • [Journal-full-title] Acta orthopaedica Belgica
  • [ISO-abbreviation] Acta Orthop Belg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Belgium
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98. Simon Cypel TK, Vijayasekaran V, Somers GR, Zuker RM: Pilomatricoma: experience of the hospital for sick children. Can J Plast Surg; 2007;15(3):159-61
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  • BACKGROUND: Pilomatricoma (calcifying epithelioma of Malherbe) is a common skin neoplasm in the pediatric population that is often misdiagnosed as other skin conditions or tumours.
  • OBJECTIVES: The objective of the present retrospective study was to review the clinical and histopathological presentation of this neoplasm in children.
  • The records of these patients were reviewed to determine sex, age, location and size of the tumour, pathological features and recurrence rate.
  • The most common sites of occurrence were the face (48%), neck (21%) and upper limbs (18%).
  • CONCLUSIONS: This entity should be considered with other benign or malignant conditions in the clinical differential diagnosis of solitary firm skin nodules, especially those on the face, neck and upper limbs.

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  • (PMID = 19554149.001).
  • [ISSN] 1195-2199
  • [Journal-full-title] The Canadian journal of plastic surgery = Journal canadien de chirurgie plastique
  • [ISO-abbreviation] Can J Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2687500
  • [Keywords] NOTNLM ; Calcifying epithelioma of Malherbe / Pilomatricoma / Pilomatrixoma
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99. Sakai H, Minemura T, Ito N, Miyazawa H, Kurashina K: Isolated osteochondroma near the mandibular angle. Int J Oral Maxillofac Surg; 2007 Mar;36(3):274-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A benign tumour of osseous and cartilaginous origins, osteochondroma generally develops in osseous tissue and is frequently found near the end of long bones.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Osteochondroma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 17052896.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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100. Galvan O, Gassner EM, Neher A, Gunkel AR: Fibro-osseous lesion of the middle turbinate: ossifying fibroma or fibrous dysplasia? J Laryngol Otol; 2007 Dec;121(12):1201-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign fibro-osseous tumours of the head and neck region seldom appear in the midface and nasal cavity.
  • The rather uncommon case of a 14-year-old boy with a tumour of the middle turbinate is presented.
  • The radiologic appearance of the tumour, on computed tomography and magnetic resonance imaging scans, was consistent with fibrous dysplasia.
  • Angiography revealed extensive vascularisation of the tumour from both the internal and external carotid arteries.
  • The tumour was completely resected via an endoscopic approach.

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  • (PMID = 17349097.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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