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1. Garteiz-Martínez D, Romero-Lagarza P, Maya-Goldsmit D, Weber-Sánchez A, Bravo-Torreblanca C, Carbo-Romano R, Vega-Rivera F: [Pelvic solitary fibrous nodule, incidental finding and laparoscopic resection. Case report]. Ginecol Obstet Mex; 2010 Sep;78(9):504-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Nódulo fibroso solitario pélvico, hallazgo incidental y resección laparoscópica. Reporte de un caso.
  • The solitary fibrous nodule is a rare clinical disease that mainly affects the pleura, but has been occasionally described in other anatomical sites.
  • A peritoneal pelvic tumor with smooth surface, 20,2 g, firm was detected.
  • The histopathologic report described that the tumor contained sclerosed cells with collagenous bands and sings of hemorrhage and calcification, compatible with a benign pelvic solitary fibrous tumor.
  • The solitary fibrous nodule is a rare, benign disease, but with malignant potential.
  • [MeSH-major] Fibroma / complications. Peritoneal Neoplasms / complications. Pregnancy Complications, Neoplastic / diagnosis. Pregnancy, Ectopic / surgery

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  • (PMID = 21961368.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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2. Larsen SR, Godballe C, Krogdahl A: Solitary fibrous tumor arising in an intrathoracic goiter. Thyroid; 2010 Apr;20(4):435-7
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  • [Title] Solitary fibrous tumor arising in an intrathoracic goiter.
  • BACKGROUND: Solitary fibrous tumor (SFT) is a rare spindle cell tumor most often found in the mediastinal pleura.
  • Complete surgical removal of tumor is the treatment of choice.
  • All cases of this site of origin reported have had a benign clinical course.
  • [MeSH-major] Solitary Fibrous Tumors / diagnosis
  • [MeSH-minor] Antigens, CD34 / metabolism. Goiter / diagnosis. Humans. Male. Middle Aged. Proto-Oncogene Proteins c-bcl-2 / metabolism. Thyroid Neoplasms / diagnosis. Tomography, X-Ray Computed. Vimentin / metabolism

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  • (PMID = 20373988.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2; 0 / Vimentin
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3. Garrido Abad PG, Del Peso AC, Herranz Fernández LM, Jiménez Gálvez M, Bocardo Fajardo G, Arellano Gañán RA, Arellano Sanz IA, Reina Durán TR: [Solitary malignant fibrous inguinal tumor. Case report]. Arch Esp Urol; 2007 Dec;60(10):1.200-1.203
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary malignant fibrous inguinal tumor. Case report].
  • [Transliterated title] Tumor fibroso solitario inguinal maligno. Aportación de un caso.
  • OBJECTIVE: Solitary fibrous tumours (SFTs) are rare neoplasias that were first reported in pleura, but can occur in different sites.
  • After surgical extirpation, solitary fibrous tumour was diagnosed.
  • CONCLUSIONS: The vast majority of solitary fibrous tumours (SFTs) have a benign course.
  • [MeSH-major] Inguinal Canal. Solitary Fibrous Tumors / diagnosis

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  • (PMID = 18273978.001).
  • [ISSN] 0004-0614
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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4. Cardinale L, Ardissone F, Garetto I, Marci V, Volpicelli G, Solitro F, Fava C: Imaging of benign solitary fibrous tumor of the pleura: a pictorial essay. Rare Tumors; 2010;2(1):e1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Imaging of benign solitary fibrous tumor of the pleura: a pictorial essay.
  • Solitary fibrous tumor of the pleura (SFTP) is a mesenchymal tumor that tends to involve the pleura, and is also described in other thoracic and extrathoracic sites.
  • SFTP usually presents as a peripheral mass abutting the pleural surface, to which it is attached by a broad base or by a pedicle that allows it to be mobile.
  • SFTPs exist in benign and malignant forms.
  • A precise pre-operative diagnosis can be arrived at with a cutting-needle biopsy, although most cases are diagnosed with postoperative histology and immunohistochemical analysis.

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  • (PMID = 21139938.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994496
  • [Keywords] NOTNLM ; computed tomography / pleura / solitary fibrous tumor of the pleura / tumor / ultrasonography
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5. Martínez Martínez P, Moldes Rodríguez M, Moreno Mata N, Simón Adiego C, Cebollero Presmanes M, González Aragoneses F: [Immunohistochemistry and surgical approaches in solitary fibrous tumor of the pleura]. Cir Esp; 2007 Mar;81(3):155-8
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  • [Title] [Immunohistochemistry and surgical approaches in solitary fibrous tumor of the pleura].
  • [Transliterated title] Inmunohistoquímica y vías de abordaje en el tumor fibroso pleural.
  • Solitary fibrous tumor of the pleura (SFTP) is a rare, benign, slow-growing neoplasm that arises from the submesothelial cells of the pleura.
  • Usually, resection of the tumor and adjacent structures are sufficient for resolution.
  • Only four patients were symptomatic at diagnosis.
  • Because of the malignant potential of this tumor, long-term follow-up is mandatory.
  • [MeSH-major] Neoplasms, Fibrous Tissue / immunology. Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / immunology. Pleural Neoplasms / surgery. Thoracic Surgery, Video-Assisted / instrumentation
  • [MeSH-minor] Adult. Aged. Antigens, CD34 / immunology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Mesothelioma / immunology. Mesothelioma / pathology. Mesothelioma / surgery. Middle Aged

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  • (PMID = 17349242.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, CD34
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6. Emanuel P, Qin L, Harpaz N: Calcifying fibrous tumor of small intestine. Ann Diagn Pathol; 2008 Apr;12(2):138-41
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  • [Title] Calcifying fibrous tumor of small intestine.
  • Calcifying fibrous tumor (CFT) is a rare benign tumor with a predilection for children and young adults that usually arises in the subcutaneous and deep soft tissues, pleura, or peritoneum.
  • Calcifying fibrous tumor of the gastrointestinal tract is exceedingly rare and therefore prone to confusion with other spindle cell lesions more commonly encountered in this location.
  • We describe 4 cases of calcifying fibrous tumor arising in the terminal ileum, one of which caused the heretofore unreported complication of intestinal intussusception, and discuss the differential diagnosis with other common and uncommon spindle cell lesions.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Fibromatosis, Aggressive / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. Humans. Male

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  • (PMID = 18325476.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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7. Dango S, Kirschbaum B, Passlick B: [Solitary fibroma of the pleura - clinical findings and prognosis]. Zentralbl Chir; 2008 Jun;133(3):227-30
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  • [Title] [Solitary fibroma of the pleura - clinical findings and prognosis].
  • [Transliterated title] Solitäre fibröse Tumoren der Pleura - Klinik und Prognose.
  • Solitary fibrous tumours of the pleura can arise from either the visceral or the parietal pleura.
  • Female and male subjects are affected equally; solitary tumours of the pleura are found at all ages with a main incidence in the sixth and seventh decades.
  • The current literature describes the origin of both benign and malign tumour cells as being from multipotential submesothelial fibrous cells.
  • The clinical appearance is unspecific and characteristic symptoms are lacking; cough, feeling of pressure in the thoracic chest or dyspnoea are the main leading symptoms and correlate with tumour size.
  • Frequently, a solitary tumour of the pleura is found incidentally.
  • Paraneoplastic syndromes are described and hypertrophic pulmonary osteoarthropathia (HPO) is the most common in cases of a solitary fibrous tumour of the pleura.
  • Patients with a benign solitary fibrous tumour of the pleura have a far better survival compared to those with the malignant variant.
  • In two recent reviews, the 5- and 10-year survival rates are described as being 97 and 90 %, respectively, for benign tumours compared with 89 and 88 % for malignant fibromas.
  • [MeSH-major] Pleural Neoplasms / surgery. Solitary Fibrous Tumor, Pleural / surgery
  • [MeSH-minor] Diagnosis, Differential. Disease-Free Survival. Humans. Incidental Findings. Osteoarthropathy, Secondary Hypertrophic / radiography. Paraneoplastic Syndromes / radiography. Pleura / pathology. Pleura / surgery. Prognosis. Tomography, X-Ray Computed

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  • (PMID = 18563686.001).
  • [ISSN] 0044-409X
  • [Journal-full-title] Zentralblatt für Chirurgie
  • [ISO-abbreviation] Zentralbl Chir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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8. Szczepulska-Wójcik E, Langfort R, Roszkowski-Sliz K: [A comparative evaluation of immunohistochemical markers for the differential diagnosis between malignant mesothelioma, non-small cell carcinoma involving the pleura, and benign reactive mesothelial cell proliferation]. Pneumonol Alergol Pol; 2007;75(1):57-69
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  • [Title] [A comparative evaluation of immunohistochemical markers for the differential diagnosis between malignant mesothelioma, non-small cell carcinoma involving the pleura, and benign reactive mesothelial cell proliferation].
  • INTRODUCTION: Histopathological diagnosis of malignant mesothelioma (MM) and differentiating it from tumors infiltrating the pleura is very difficult.
  • Distinguishing benign reactive mesothelial cell proliferation from MM also presents problems.
  • The objective of this study was to evaluate the significance of selected immunohistochemical stains in differentiating MM from non-small cell lung cancers infiltrating the pleura and from benign reactive mesothelial cell proliferation.
  • MATERIAL AND METHODS: The material encompassed 86 cases of MM, 54 cases of NSCLC infiltrating the pleura, and 43 cases of benign reactive mesothelial cell proliferation.
  • Non-small cell lung cancers infiltrating the pleura: Coexpression of cytokeratin and vimentin was found in 17.6% of the cases, positive staining of membranes for EMA, in 13% cases.
  • Benign reactive mesothelial cell proliferation: Protein p53 was present in 9.3% of cases, whereas no positive staining for EMA was found.
  • In the diagnosis of spindle-cell pleural tumors and the fibrous form of MM and benign reactive mesothelial cell proliferation , markers of mesothelial cells are noncontributory.
  • Immunohistochemical staining fails to identify a reactive process, but a diffuse, positive stain for EMA and the presence of protein p53 support the diagnosis of MM.
  • [MeSH-major] Antigens, Tumor-Associated, Carbohydrate / analysis. Biomarkers, Tumor / analysis. Carcinoma, Non-Small-Cell Lung / pathology. Mesothelioma / pathology. Neoplasm Proteins / analysis. Neoplasms, Mesothelial / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Aged. Antibodies, Monoclonal / analysis. Diagnosis, Differential. Epithelium / chemistry. Epithelium / pathology. Female. Humans. Hyperplasia / pathology. Immunohistochemistry. Lung / chemistry. Lung / pathology. Male. Middle Aged. Pleura / chemistry. Pleura / pathology. Pleural Effusion / chemistry. Sensitivity and Specificity

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  • (PMID = 17541913.001).
  • [ISSN] 0867-7077
  • [Journal-full-title] Pneumonologia i alergologia polska
  • [ISO-abbreviation] Pneumonol Alergol Pol
  • [Language] pol
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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9. Garg K, Lee P, Ro JY, Qu Z, Troncoso P, Ayala AG: Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 cases. Ann Diagn Pathol; 2005 Feb;9(1):11-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Adenomatoid tumor of the adrenal gland: a clinicopathologic study of 3 cases.
  • Adenomatoid tumors are relatively uncommon benign neoplasms of mesothelial origin, usually occurring in the male and female genital tracts.
  • Rare extragenital adenomatoid tumors have been identified in the adrenal glands, heart, mesentery, pleura, and lymph nodes.
  • The differential diagnosis includes adrenocortical carcinoma and metastatic carcinoma, especially signet ring cell carcinoma.
  • Because of its glandular pattern, an adenomatoid tumor may be confused with an adenocarcinoma.
  • The tumor was an incidental radiological finding in another case and was discovered during the course of a workup for hypertension in the third case.
  • In our experience, the key to the diagnosis of this rare benign tumor is to consider adenomatoid tumor in the differential diagnosis of any glandular tumor occurring in the adrenal gland.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adult. Biomarkers, Tumor / metabolism. Calbindin 2. Carcinoma, Signet Ring Cell / diagnosis. Carcinoma, Signet Ring Cell / secondary. Cysts / complications. Cysts / metabolism. Cysts / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Keratins / metabolism. Male. Middle Aged. S100 Calcium Binding Protein G / metabolism. Treatment Outcome

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  • (PMID = 15692945.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 68238-35-7 / Keratins
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10. Radak V, Radovanović D, Grubor N, Micev M, Colović R: [Solitary fibrous tumor of the visceral pleura of the right lung base]. Srp Arh Celok Lek; 2006 Sep-Oct;134(9-10):441-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary fibrous tumor of the visceral pleura of the right lung base].
  • Within thorax, they usually originate from pleura, most frequently the visceral one.
  • Authors present a 67- year old male in whom the tumor was diagnosed during the investigation for dyspnea.
  • During operation, solitary, well circumscribed, firm, ruber-like tumour, 11 x 10 x 9 cm in diameter, covered with serosa, arising from the visceral pleura of the base of the right lung was easily excised.
  • The classical histological and immunohistochemical examinations confirmed the diagnosis of benign fibrous tumor.
  • [MeSH-major] Fibroma / pathology. Pleural Neoplasms / pathology

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  • (PMID = 17252914.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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11. Heffner JE, Klein JS: Recent advances in the diagnosis and management of malignant pleural effusions. Mayo Clin Proc; 2008 Feb;83(2):235-50
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recent advances in the diagnosis and management of malignant pleural effusions.
  • Malignant pleural effusions (MPEs) are an important complication for patients with intrathoracic and extrathoracic malignancies.
  • Median survival after diagnosis of an MPE is 4 months.
  • However, almost all tumor types have been reported to cause MPEs.
  • New imaging modalities assist the evaluation of patients with a suspected MPE; however, positive cytologic or tissue confirmation of malignant cells is necessary to establish a diagnosis.
  • Even in the presence of known malignancy, up to 50% of pleural effusions are benign, underscoring the importance of a firm diagnosis to guide therapy.
  • This review summarizes the pathogenesis, diagnosis, and management of MPE.
  • Studies in the English language were identified by searching the MEDLINE database (1980-2007) using the search terms pleura, pleural, malignant, pleurodesis, and thoracoscopy.
  • [MeSH-major] Pleural Effusion, Malignant / diagnosis. Pleural Effusion, Malignant / therapy

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  • [ErratumIn] Mayo Clin Proc. 2009 Sep;84(9):847
  • (PMID = 18241636.001).
  • [ISSN] 0025-6196
  • [Journal-full-title] Mayo Clinic proceedings
  • [ISO-abbreviation] Mayo Clin. Proc.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 224
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12. Liu J, He JX, Cai CJ, Chen HZ, Wei B, Shao WL, Li SB: [The analysis on the misdiagnosis of solitary fibrous tumor of the pleura]. Zhonghua Jie He He Hu Xi Za Zhi; 2010 Jun;33(6):432-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The analysis on the misdiagnosis of solitary fibrous tumor of the pleura].
  • OBJECTIVE: To report the characteristics of solitary fibrous tumor of the pleura (SFTP), and to analyze the factors associated with the misdiagnosis of this disease.
  • RESULTS: The preoperative diagnosis was pleural mesothelioma in 7 cases, neurogenic tumor in 6, lung cancer in 4, SFTP in 2, hilar lymph node tuberculosis in 1 and inflammatory granuloma in 1 case.
  • All the cases underwent radical resection, and postoperative pathology and immunohistochemical study were performed, and the diagnosis of benign solitary fibrous tumor of the pleura was confirmed.
  • CONCLUSION: The recognition of the clinical characteristics of pleural solitary fibrous tumor is essential for improving the diagnosis of this uncommon disease.
  • [MeSH-major] Diagnostic Errors. Pleural Neoplasms / diagnosis. Solitary Fibrous Tumor, Pleural / diagnosis

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  • (PMID = 20979815.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Ohar JA, Ampleford EJ, Howard SE, Sterling DA: Identification of a mesothelioma phenotype. Respir Med; 2007 Mar;101(3):503-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Despite the strong association of asbestos exposure to mesothelioma, only a fraction of persons exposed develop this neoplasm which is characterized by long latency and shortened survival.
  • To identify a more extensive set of traits that would define a mesothelioma phenotype for the purpose of genetic analysis, we set to determine characteristics that distinguish mesothelioma patients from others exposed to asbestos and to identify factors that predict the presence of mesothelioma over other mesenchymal tumors of the peritoneum and carcinoma metastatic to the pleura.
  • We compared demographics in four asbestos-exposed groups (controls n=347, bronchogenic cancer n=67, mesothelioma n=179 and benign asbestos-induced lung disease (BALD) n=3757).
  • We found that compared to other asbestos-exposed groups, subjects with mesothelioma were younger at first asbestos exposure, had a greater risk of a second cancer diagnosis (odds ratio=3.29), had a longer disease latency, and had a greater risk of cancer among first-degree relatives (point estimate for risk 2.93; 95% CI 2.5-3.5).
  • Thoracic tumor location, work exposure and male gender were consistently associated with shortened survival (1.9+/-1.3 years).
  • We conclude that thoracic tumor location, work exposure, male gender, long latency, early age at first exposure, presence of a second cancer, and first-degree relative with cancer define a phenotype that sets mesothelioma patients with a short survival apart from other asbestos-exposed individuals.
  • [MeSH-minor] Age Factors. Aged. Educational Status. Family Health. Female. Humans. Male. Middle Aged. Neoplasms, Multiple Primary. Occupational Exposure / adverse effects. Peritoneal Neoplasms / genetics. Peritoneal Neoplasms / mortality. Phenotype. Pleural Neoplasms / genetics. Pleural Neoplasms / mortality. Risk Factors. Sex Factors. Smoking / adverse effects


14. Heyer CM, Kagel T, Lemburg SP, Walter JW, de Zeeuw J, Junker K, Mueller KM, Nicolas V, Bauer TT: Transbronchial biopsy guided by low-dose MDCT: a new approach for assessment of solitary pulmonary nodules. AJR Am J Roentgenol; 2006 Oct;187(4):933-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SUBJECTS AND METHODS: We included 33 consecutive patients (25 men; mean age +/- SD, 64 +/- 9.6 years) with solitary pulmonary nodules at different sites and with a lesion-to-pleura distance of at least 2 cm who previously underwent conventional bronchoscopy that did not result in histologic diagnosis.
  • RESULTS: The diagnostic yield was 24 in 33 selected patients (overall accuracy, 72.7%): 13 (54%) had primary lung cancer and 11 (46%) had benign diagnoses.
  • The final diagnoses of the remaining nine patients in whom transbronchial bronchoscopic biopsy was not diagnostic were non-small cell lung cancer (n = 3); small cell lung cancer (n = 3); and alveolar carcinoma, carcinoid tumor, and hemorrhaged bulla (n = 1 each).
  • [MeSH-major] Biopsy, Needle / methods. Lung / pathology. Lung Neoplasms / diagnosis. Radiography, Interventional. Solitary Pulmonary Nodule / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 16985137.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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15. Tanaka M, Sawai H, Okada Y, Yamamoto M, Funahashi H, Hayakawa T, Takeyama H, Manabe T: Malignant solitary fibrous tumor originating from the peritoneum and review of the literature. Med Sci Monit; 2006 Oct;12(10):CS95-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant solitary fibrous tumor originating from the peritoneum and review of the literature.
  • BACKGROUND: Solitary fibrous tumor (SFT) is a rare neoplasm frequently involving the pleura.
  • Benign and malignant forms of the tumor occur, the benign variant being three to four times more common than the malignant.
  • CASE REPORT: We present herein a rare case of large malignant solitary fibrous tumor (SFT) originating from the peritoneum.
  • An abdominal computed tomography scan revealed a well-defined solid tumor with mixed density.
  • An abdominal ultrasonography (US) revealed a well-circumscribed solid tumor containing a partially cystic lesion.
  • Liposarcoma originating from the retroperitoneum was suggested, and the patient underwent a complete resection of the tumor as well as the left kidney because tumor invasion of the upper left kidney was suspected.
  • Immunohistochemically, the spindle-shaped cells were positive for CD34, and the diagnosis was SFT originating from the peritoneum.
  • CONCLUSIONS: This case gave us some difficulty, and the correct diagnosis of the peritoneal mass was valuable.
  • To diagnose the malignant potential of this type of tumor accurately may have value to direct the appropriate therapeutic operations after surgery and postoperative progress observation.
  • [MeSH-major] Neoplasms, Fibrous Tissue / diagnosis. Neoplasms, Fibrous Tissue / pathology. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / pathology

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  • (PMID = 17006407.001).
  • [ISSN] 1234-1010
  • [Journal-full-title] Medical science monitor : international medical journal of experimental and clinical research
  • [ISO-abbreviation] Med. Sci. Monit.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antigens, CD34
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16. Alobid I, Alós L, Maldonado M, Menéndez LM, Bernal-Sprekelsen M: Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report. Eur Arch Otorhinolaryngol; 2005 Apr;262(4):286-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laryngeal solitary fibrous tumor treated with CO2 laser excision: case report.
  • The solitary fibrous tumor is an uncommon unilateral benign lesion that usually arises from the pleura.
  • To date, only two cases of solitary fibrous tumor arising from the larynx have been reported in the scientific literature.
  • We describe a new case of laryngeal solitary fibrous tumor localized at the right false vocal fold.
  • A mass lesion was recognized in the right false vocal fold, and CT scan demonstrated a large, well-defined tumor without signs of infiltration.
  • The tumor was removed by transoral CO(2) laser surgery.
  • The definitive diagnosis was obtained by immunohistochemical analysis that showed vimentin and CD34-positive cells.
  • The patient remains free of tumor after 15 months of follow-up.

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  • [Cites] Mod Pathol. 1999 Nov;12(11):1034-42 [10574600.001]
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  • (PMID = 15170575.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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17. Saka H: [Ultrathin bronchoscopy]. Kyobu Geka; 2007 Jul;60(8 Suppl):734-8
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  • To evaluate the clinical benefits of ultrathin bronchoscope in the pathological diagnosis of peripheral lung lesions, we routinely used a 2.8 mm outer diameter ultrathin for the peripheral lesions with fluoroscopic guidance.
  • The diagnostic rates were not different as to the size of the tumor of less than 2.0 cm or more.
  • In the final diagnoses of benign lesions 39% received pathological diagnosis at the first bronchoscopy.
  • In 2 patients, ultrathin scope penetrated visceral pleura.
  • Ultrathin bronchoscopy is a safe and reliable method to obtain the pathological specimen in the diagnosis of peripheral lesions under fluoroscopic guidance.
  • [MeSH-minor] Biopsy / instrumentation. Humans. Lung Diseases / diagnosis. Retrospective Studies

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  • (PMID = 17763677.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Japan
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18. Hayakawa M: [Pleural lipoma: report of a case]. Kyobu Geka; 2005 Dec;58(13):1185-8
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  • [Title] [Pleural lipoma: report of a case].
  • Although lipomas are the most common form of the benign neoplasm, occurrence within the thoracic cage is uncommon, and lipomas originating from the pleura are very rare.
  • A chest wall tumor was suspected based on the findings of computed tomography (CT) of the thorax.
  • The tumor was resected by video-assisted thoracoscopic surgery and the patient remains well with no recurrence 4 years postoperatively.
  • The resected tumor was a yellowish pleural mass and the pathological diagnosis was a benign lipoma.
  • It is possible to make a diagnosis of lipoma preoperatively by CT and magnetic resonance imaging (MRI), however, the correct differential diagnosis of lipoma and liposarcoma is imperfect only by radiological findings necessitating surgical removal if possible.
  • [MeSH-major] Lipoma / surgery. Pleural Neoplasms / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 16359024.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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19. Cardillo G, Carbone L, Carleo F, Masala N, Graziano P, Bray A, Martelli M: Solitary fibrous tumors of the pleura: an analysis of 110 patients treated in a single institution. Ann Thorac Surg; 2009 Nov;88(5):1632-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura: an analysis of 110 patients treated in a single institution.
  • BACKGROUND: Solitary (localized) fibrous tumors of the pleura (SFTP) are rare slow-growing neoplasms that generally have a favorable prognosis.
  • The visceral pleura was the site of origin in 95 tumors, the parietal pleura in 13, the mediastinal pleura in 2 cases.
  • Tumors were pathologically benign in 95 cases (86.4%), and malignant in 15 (13.6%).
  • The overall disease-free survival rate was 90.8% (95.7% in benign cases and 67.1% in malignant cases; p < 0.05).
  • Eight patients presented with recurrence of disease, 4 cases of which were malignant and 4 were benign.
  • CONCLUSIONS: Solitary fibrous tumor of the pleura is a rare disease that includes both benign and malignant variants.The outcome is mostly benign, with an overall 10-year survival rate of 97.5%.
  • Pathologically benign lesions show a better disease-free survival rate than malignant lesions (95.7% versus 67.1%; p < 0.05).
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / surgery

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  • (PMID = 19853123.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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20. Fujiu K, Miyamoto H, Sakuma H, Mori M: Solitary fibrous tumors of the pleura presenting satellite tumors. Gen Thorac Cardiovasc Surg; 2009 Jul;57(7):382-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura presenting satellite tumors.
  • Computed tomography revealed a tumor adjacent to the diaphragm.
  • A sessile tumor measuring 10.5 x 8.5 x 4.5 cm arising from the parietal pleura was resected.
  • The tumor was accompanied by several little tumors on the nearby diaphragm.
  • Pathologically, the major tumor consisted of typical spindle-shaped cells with myxoid degeneration.
  • We diagnosed benign solitary fibrous tumor of the pleura with satellite tumors.
  • We must be aware of the possibility of satellite tumors when we treat patients with a benign solitary fibrous tumor.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / pathology

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  • [Cites] Am J Surg Pathol. 1989 Aug;13(8):640-58 [2665534.001]
  • [Cites] Ann Thorac Surg. 2006 Jul;82(1):342-5 [16798253.001]
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  • (PMID = 19597930.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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21. Gómez-Oliveira G, Alvarez-Flores M, Arribas-García I, Martínez-Gimeno C: Solitary fibrous tumor surrounding the carotid sheath. Med Oral Patol Oral Cir Bucal; 2010 Mar;15(2):e395-7
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  • [Title] Solitary fibrous tumor surrounding the carotid sheath.
  • Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms that are mostly found arising from the pleura.
  • SFTs are benign in most cases.
  • In this article, we present a case of a Solitary Fibrous Tumor arising in the parapharyngeal space in a 20-year-old man, involving the carotid sheath, treated by surgical excision with no recurrence after 1 year.

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  • (PMID = 19767703.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Spain
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22. Gratzinger D, Zhao S, West R, Rouse RV, Vogel H, Gil EC, Levy R, Lossos IS, Natkunam Y: The transcription factor LMO2 is a robust marker of vascular endothelium and vascular neoplasms and selected other entities. Am J Clin Pathol; 2009 Feb;131(2):264-78
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  • The transcription factor LMO2 is involved in vascular and hematopoietic development and hematolymphoid neoplasia.
  • LMO2 is uniformly expressed in benign vascular and lymphatic neoplasms and in most malignant vascular neoplasms with the exception of epithelioid vascular neoplasms of pleura and bone.
  • Among nonvascular neoplasms, LMO2 reactivity is present in giant cell tumor of tendon sheath, juvenile xanthogranuloma, a subset of gastrointestinal stromal tumors, small round blue cell tumors, and myoepithelial-derived neoplasms.

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  • (PMID = 19141387.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P01 CA034233; United States / NCI NIH HHS / CA / CA34233; United States / NCI NIH HHS / CA / CA122105; United States / NCI NIH HHS / CA / CA33399; United States / NCI NIH HHS / CA / R37 CA033399; United States / NCI NIH HHS / CA / R01 CA109335; United States / NCI NIH HHS / CA / R01 CA122105; United States / NCI NIH HHS / CA / CA109335; United States / NCI NIH HHS / CA / P30 CA124435
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / Biomarkers, Tumor; 0 / DNA-Binding Proteins; 0 / LIM Domain Proteins; 0 / LMO2 protein, human; 0 / Metalloproteins; 0 / Proto-Oncogene Proteins
  • [Other-IDs] NLM/ NIHMS636776; NLM/ PMC4305438
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23. Grigoriu BD, Scherpereel A, Devos P, Chahine B, Letourneux M, Lebailly P, Grégoire M, Porte H, Copin MC, Lassalle P: Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment. Clin Cancer Res; 2007 May 15;13(10):2928-35
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  • [Title] Utility of osteopontin and serum mesothelin in malignant pleural mesothelioma diagnosis and prognosis assessment.
  • PURPOSE: Malignant mesothelioma is a highly aggressive tumor and is often diagnosed too late for a curative treatment.
  • We compared diagnostic and prognostic values of mesothelin and osteopontin in 172 patients suspected of malignant pleural mesothelioma (MPM) and in a control group of 112 asymptomatic asbestos-exposed subjects.
  • EXPERIMENTAL DESIGN: Osteopontin and mesothelin were assayed with commercial ELISA kits in a series of 43 patients with pleural metastases of various carcinomas, 33 patients with benign pleural lesions associated with asbestos exposure, 96 patients with MPMs, and 112 asbestos-exposed healthy subjects.
  • Results were correlated with patient's diagnosis and survival.
  • However, osteopontin was unable to distinguish between MPM and pleural metastatic carcinoma or benign pleural lesions associated with asbestos exposure.
  • Neither plasma nor pleural fluid osteopontin were more powerful in this respect.
  • Survival analysis identified tumor histologic subtype along with serum osteopontin and serum mesothelin as independent prognostic factors in mesothelioma patients.
  • [MeSH-major] Membrane Glycoproteins / blood. Mesothelioma / diagnosis. Osteopontin / blood. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Aged. Extracellular Fluid / chemistry. Female. GPI-Linked Proteins. Humans. Male. Middle Aged. Pleura / chemistry. Prognosis. Survival Analysis

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  • (PMID = 17504993.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / mesothelin; 106441-73-0 / Osteopontin
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24. Liu FY, Wang MQ, Fan QS, Duan F, Wang ZJ, Song P: Supplementary inferior phrenic artery embolization in the interventional treatment of hemoptysis. Chin Med J (Engl); 2009 Mar 5;122(5):514-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In 11 cases, contrast material was seen in vessels supplying the tumor and in the tumor.
  • Lesions were closely related to the pleura in 25 patients.
  • Fifteen lesions were close to the diaphragmatic pleura, seven close to the mediastinal pleura, and three close to the lateral pleura of the lower lung.
  • Eleven cases had inferior thoracic pleural thickening and adhesions.
  • The involvement of IPA in the blood supply of the hemoptysis was not correlated with the characteristic of the lung lesions (benign or malignant) (P = 1.0000).

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  • (PMID = 19323900.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
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25. D'Andrilli A, Andreetti C, Ibrahim M, Rendina EA: The evolution of a pleural nodule into a giant fibrous tumor associated with hypoglycemic coma. Eur J Cardiothorac Surg; 2007 May;31(5):955-7
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  • [Title] The evolution of a pleural nodule into a giant fibrous tumor associated with hypoglycemic coma.
  • We hereby present the exceptional case of hypoglycemic coma associated with a giant benign localized fibrous tumor of the pleura (LFTP).
  • A fine needle aspiration biopsy provided a diagnosis of LFTP, but the patient refused surgery.
  • The tumor was completely resected, and complete relief of the hypoglycemic and respiratory symptoms was achieved.
  • [MeSH-major] Insulin Coma / etiology. Neoplasms, Fibrous Tissue / complications. Pleural Neoplasms / complications

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  • (PMID = 17317199.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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26. Kawamura S, Nakamura T, Oya T, Ishizawa S, Sakai Y, Tanaka T, Saito S, Fukuoka J: Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy. Pathol Int; 2007 Apr;57(4):213-8
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  • [Title] Advanced malignant solitary fibrous tumor in pelvis responding to radiation therapy.
  • Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm that is benign in most cases.
  • Although SFT was first recognized to arise only in the pleura, recent reports indicate that SFT can involve a wide range of anatomical sites.
  • Along with massive invasion to adjacent organs and multiple lung metastases detected on radiography, biopsy from the tumor through the vaginal wall showed malignant looking spindle-cell neoplasm with increased cellularity, areas of necrosis, and high mitotic activity (5/10 high-power fields).
  • Immunohistochemically, the tumor cells were diffusely and strongly positive for CD34, CD99, and bcl-2.
  • Based on pathological features and clinical presentation, diagnosis of malignant SFT was made.
  • Initial chemotherapies failed to control the tumor.
  • [MeSH-minor] Aged. Disease Progression. Female. Humans. Magnetic Resonance Imaging. Neoplasm Metastasis / pathology

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  • (PMID = 17316417.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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27. Sakurai H, Kaji M, Yamazaki K, Suemasu K: Intrathoracic lipomas: their clinicopathological behaviors are not as straightforward as expected. Ann Thorac Surg; 2008 Jul;86(1):261-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Lipomas are a common type of benign tumor, and may involve numerous sites.
  • Symptoms caused by the tumor were seen in only one patient.
  • Intrathoracic lipomas were most frequently seen in the parietal pleura.
  • The resected tumor size ranged from 1.0 to 6.0 cm.
  • One of these three ended in an incomplete resection because the tumor infiltrated the brachial plexus.
  • One patient had a recurrent tumor arising from a resected margin.
  • CONCLUSIONS: Intrathoracic lipomas should be surgically resected if they are detected, because the possibility of liposarcoma or infiltrating development of the tumor cannot be excluded preoperatively.
  • We think that surgical resection of the tumor, rather than conservative management by close observation alone, is a safer treatment.
  • [MeSH-major] Lipoma / diagnosis. Lipoma / surgery. Precancerous Conditions / surgery. Thoracic Neoplasms / diagnosis. Thoracic Neoplasms / surgery

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  • (PMID = 18573434.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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28. Cerdá-Nicolás M, Löpez-Gines C, Gil-Benso R, Benito R, Pellin A, Ruiz-Saurí A, Sanchos-Garcia J, Roldan P, Talamantes F, Barberá J: Solitary fibrous tumor of the orbit: morphological, cytogenetic and molecular features. Neuropathology; 2006 Dec;26(6):557-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the orbit: morphological, cytogenetic and molecular features.
  • Solitary fibrous tumor (SFT), a benign neoplasm arising in mesenchymal structures, was initially described in the pleura but subsequently has also been documented in other locations.
  • It is uncommon in the orbit, where it closely resembles other benign spindle-shaped mesenchymal tumors of this area such as schwannoma, meningioma or hemangiopericytoma.
  • Measurement of DNA content revealed a DNA index of 1, indicating a diploid peak in 95% of the tumor cells.
  • No p14(ARF), p15(INK4B) and p16(INK4A) deletions or hypermethylation were observed in this benign tumor.
  • Following surgical resection and radiotherapy, the patient showed no tumor relapse after one year of follow-up.
  • [MeSH-minor] Adult. Cyclin-Dependent Kinase Inhibitor p15 / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. DNA Methylation. Exons / genetics. Female. Gene Deletion. Genes, p53 / genetics. Humans. Magnetic Resonance Imaging. Point Mutation. Proto-Oncogene Proteins c-mdm2 / genetics. Soft Tissue Neoplasms / genetics. Soft Tissue Neoplasms / pathology. Tumor Suppressor Protein p14ARF / genetics

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  • (PMID = 17203593.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Cyclin-Dependent Kinase Inhibitor p15; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p14ARF; EC 6.3.2.19 / MDM2 protein, human; EC 6.3.2.19 / Proto-Oncogene Proteins c-mdm2
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29. Levy AD, Rimola J, Mehrotra AK, Sobin LH: From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation. Radiographics; 2006 Jan-Feb;26(1):245-64
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  • [Title] From the archives of the AFIP: benign fibrous tumors and tumorlike lesions of the mesentery: radiologic-pathologic correlation.
  • Mesenteric fibromatosis, sclerosing mesenteritis, inflammatory pseudotumor, and extrapleural solitary fibrous tumor constitute a loosely associated group of benign fibrous tumors and tumorlike lesions of the mesentery.
  • Mesenteric fibromatosis is a locally aggressive, benign proliferative process that may occur sporadically or in association with familial adenomatous polyposis.
  • Sclerosing mesenteritis is a rare idiopathic disorder that most commonly produces a stellate mass within the mesentery and should be differentiated from metastatic disease, specifically metastatic carcinoid, because it frequently responds to conservative or medical management.
  • Inflammatory pseudotumor (inflammatory myofibroblastic tumor) is a benign, chronic inflammatory disorder of unknown cause that manifests as a solid mesenteric mass, indistinguishable from malignancy.
  • Extrapleural solitary fibrous tumor is a tumor of submesothelial origin that is identical to the solitary fibrous tumor of the pleura.
  • When located in the mesentery or peritoneal cavity, extrapleural solitary fibrous tumor has an imaging pattern that must be differentiated from metastatic disease, soft-tissue sarcomas, and other benign and malignant neoplasms of the mesentery and peritoneum.
  • Knowledge of this group of benign fibrous tumors and tumorlike lesions of the mesentery is important in the preoperative evaluation of a mesenteric mass.
  • [MeSH-major] Mesentery. Peritoneal Diseases / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Child. Female. Fibroma / diagnosis. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Panniculitis, Peritoneal / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 16418255.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 57
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30. Rakovich G, Laflamme M, Ouellette D, Beauchamp G: Solitary fibrous tumour of the pleura: A case report. Can Respir J; 2010 May-Jun;17(3):113-4
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  • [Title] Solitary fibrous tumour of the pleura: A case report.
  • Solitary fibrous tumours of the pleura are rare pleural neoplasms that are distinct from mesothelioma.
  • Most of them are benign, although some behave aggressively; morphological and pathological features are important in distinguishing them from mesothelioma and in predicting clinical behaviour.
  • In cases of benign lesions, complete resection is usually curative.
  • A case involving a 62-year-old woman who underwent surgical resection of a solitary fibrous tumour of the pleura measuring 25 cm in size is described.
  • [MeSH-major] Pleura / pathology. Solitary Fibrous Tumor, Pleural / pathology

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  • [Cites] J Thorac Imaging. 2005 May;20(2):118-9 [15818213.001]
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  • (PMID = 20617210.001).
  • [ISSN] 1916-7245
  • [Journal-full-title] Canadian respiratory journal
  • [ISO-abbreviation] Can. Respir. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Canada
  • [Other-IDs] NLM/ PMC2900141
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31. Fibla JJ, Gómez G, Salord N, Penagos JC, Estrada G, León C: [Giant solitary fibrous tumor of the pleura]. Cir Esp; 2005 May;77(5):290-2
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  • [Title] [Giant solitary fibrous tumor of the pleura].
  • [Transliterated title] Tumor fibroso solitario pleural gigante.
  • Primitive neoplasms of the pleura are uncommon.
  • Solitary fibrous tumor of the pleura (SFTP) is a benign variety of primitive pleural tumor, which is usually asymptomatic and discovered as an incidental finding.
  • [MeSH-major] Pleural Neoplasms / pathology

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  • (PMID = 16420936.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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32. Mizobuchi T, Masahiro N, Iwai N, Kohno H, Okada N, Nakada S: Clear cell tumor of the lung: surgical and immunohistochemical findings. Gen Thorac Cardiovasc Surg; 2010 May;58(5):243-7
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  • [Title] Clear cell tumor of the lung: surgical and immunohistochemical findings.
  • We encountered a clear cell tumor of the lung (CCTL) that was located peripherally, adjacent to the visceral pleura.
  • The tumor could be directly observed during surgery.
  • The in vivo color of the tumor was red, suddenly changing to white after the tumor was clamped.
  • Immunohistochemistry revealed tumor cells positive for vimentin and melanocytic markers (HMB-45 and melan-A) and negative for epithelial membrane antigen and cytokeratin.
  • With the absence of clinical findings in both kidneys, the tumor was diagnosed as a benign CCTL.
  • [MeSH-major] Biomarkers, Tumor / analysis. Immunohistochemistry. Lung Neoplasms / chemistry. Lung Neoplasms / surgery. Perivascular Epithelioid Cell Neoplasms / chemistry. Perivascular Epithelioid Cell Neoplasms / surgery. Thoracic Surgery, Video-Assisted
  • [MeSH-minor] Aged. Antigens, Neoplasm / analysis. Female. Humans. Incidental Findings. MART-1 Antigen. Melanoma-Specific Antigens. Neoplasm Proteins / analysis. Tomography, X-Ray Computed. Treatment Outcome. Vimentin / analysis

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  • (PMID = 20449716.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / MART-1 Antigen; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / Vimentin
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33. Alvarado-Cabrero I, Hernández S, Kelly G J, Cuenca-Buele S: [Pleura's solitary fibrous tumor. Clinical pathology analysis of 17 cases]. Rev Med Inst Mex Seguro Soc; 2006 Sep-Oct;44(5):397-402
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  • [Title] [Pleura's solitary fibrous tumor. Clinical pathology analysis of 17 cases].
  • [Transliterated title] Tumor fibroso solitario de la pleura. Análisis clínico-patológico de 17 casos.
  • INTRODUCTION: Solitary fibrous tumor of the pleura (SFTP) is a rare neoplasm that usually originates from the visceral pleura, but it can occur in a wide range of tissues.
  • Approximately 12% of pleural cases are malignant tumors and surgical excision usually become curative.
  • MATERIAL AND METHODS: We did a retrospective review of the patients who had primary pleural tumors from January 1995 to August 2005.
  • RESULTS: Among a total of 94 primary pleural tumors, 17 patients were enrolled in this study, 8 men and 9 women, with a mean age of 63 years.
  • Thirteen cases (76%) were benign and four cases (23%) were malignant.
  • CONCLUSIONS: SFTP shows a benign biologic outcome in most of the cases.
  • There are some histological characteristics that led to distinguish between benign and malign neoplasm.
  • [MeSH-major] Neoplasms, Fibrous Tissue / pathology. Pleural Neoplasms / pathology

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  • (PMID = 17207398.001).
  • [ISSN] 0443-5117
  • [Journal-full-title] Revista médica del Instituto Mexicano del Seguro Social
  • [ISO-abbreviation] Rev Med Inst Mex Seguro Soc
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Mexico
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34. Guinee DG, Allen TC: Primary pleural neoplasia: entities other than diffuse malignant mesothelioma. Arch Pathol Lab Med; 2008 Jul;132(7):1149-70
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  • [Title] Primary pleural neoplasia: entities other than diffuse malignant mesothelioma.
  • CONTEXT: Overwhelmingly, the most common neoplasm involving the pleura is metastatic carcinoma.
  • In contrast, diffuse malignant mesothelioma occurs relatively rarely; however, it is nonetheless the most common neoplasm primary to the pleura.
  • Other primary pleural neoplasms occur uncommonly or rarely, with their own prognostic and therapeutic characteristics.
  • OBJECTIVE: To review primary pleural neoplasms other than diffuse malignant mesothelioma, to better ensure correct diagnosis and optimal assessment of prognosis and treatment.
  • CONCLUSIONS: A nonexhaustive group of uncommon to rare benign and malignant primary pleural neoplasms--other than diffuse malignant mesothelioma--are presented, of which one must be aware in order to maintain an appropriate index of suspicion to include them in the differential diagnosis of a pleural tumor.
  • [MeSH-major] Pleural Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Prognosis

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  • (PMID = 18605768.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 244
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35. Yamagishi S, Koizumi K, Hirata T, Hirai K, Kurita J, Shimizu K: Experience of thoracoscopic extirpation of intrapulmonary lymphangioma. Jpn J Thorac Cardiovasc Surg; 2005 Jun;53(6):313-6
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  • Radiologically, we diagnosed this lesion as a benign cystic tumor in the lung.
  • Thoracoscopic observation revealed a cystic lesion just beneath the visceral pleura of the upper lobe adjacent to the interlobular pulmonary artery.
  • As this suggested a benign bronchogenic cyst, we performed extirpation of the cyst under thoracoscopy.

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  • (PMID = 15997754.001).
  • [ISSN] 1344-4964
  • [Journal-full-title] The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyōbu Geka Gakkai zasshi
  • [ISO-abbreviation] Jpn. J. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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36. Song SW, Jung JI, Lee KY, Kim MY, Park SH: Malignant solitary fibrous tumor of the pleura: computed tomography-pathological correlation and comparison with computed tomography of benign solitary fibrous tumor of the pleura. Jpn J Radiol; 2010 Oct;28(8):602-8
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  • [Title] Malignant solitary fibrous tumor of the pleura: computed tomography-pathological correlation and comparison with computed tomography of benign solitary fibrous tumor of the pleura.
  • PURPOSE: The aim of this study was to determine the computed tomography (CT)-pathological correlation of malignant solitary fibrous tumors of the pleura (MSFP) and to compare these findings with CT findings of benign solitary fibrous tumors of the pleura (BSFTP).
  • Pleural metastasis (57.1%) and lung metastasis (14.3%) were associated.
  • MSFPs showed a higher incidence of intratumoral low-attenuation areas (P = 0.034) and pleural metastasis (P = 0.009); and on CT, MSFPs tended to be larger than BSFTPs (P = 0.076).
  • CONCLUSION: MSFPs showed a >10 cm pleural mass with low-attenuation regions on CT, which corresponded to hemorrhage, necrosis, cystic, or myxoid degeneration.
  • MSFPs had a higher incidence of intratumoral low-attenuation areas and pleural metastasis, and on CT they tended to be larger than BSFTPs.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / diagnostic imaging. Tomography, X-Ray Computed / methods

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  • (PMID = 20972860.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media
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37. Bodtger U, Pedersen JH, Skov BG, Clementsen P: Giant solitary fibrous tumour of the pleura: a rare but usually benign intrathoracic neoplasm. Clin Respir J; 2009 Apr;3(2):109-11
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  • [Title] Giant solitary fibrous tumour of the pleura: a rare but usually benign intrathoracic neoplasm.
  • METHODS: A case report of an 83-year-old women with progressing dyspnoea secondary to a huge left-side neoplasm.
  • RESULTS: Work-up reveal an FEV(1) of 0.4 L, and a giant solitary fibrous tumor of the pleura.
  • The tumor was surgically removed in toto without complications: weighting approximately 3 kg, and benign histology.
  • CONCLUSION: Safe and curative surgery is possible in patients with extrapulmonal neoplasm despite poor FEV(1).
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / pathology. Solitary Fibrous Tumor, Pleural / surgery. Thoracic Surgical Procedures / methods
  • [MeSH-minor] Aged, 80 and over. Biopsy, Needle. Dyspnea / diagnosis. Dyspnea / etiology. Female. Follow-Up Studies. Humans. Immunohistochemistry. Postoperative Care / methods. Preoperative Care / methods. Radiography, Thoracic. Severity of Illness Index. Thoracotomy / methods. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20298386.001).
  • [ISSN] 1752-699X
  • [Journal-full-title] The clinical respiratory journal
  • [ISO-abbreviation] Clin Respir J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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38. Harrison-Phipps KM, Nichols FC, Schleck CD, Deschamps C, Cassivi SD, Schipper PH, Allen MS, Wigle DA, Pairolero PC: Solitary fibrous tumors of the pleura: results of surgical treatment and long-term prognosis. J Thorac Cardiovasc Surg; 2009 Jul;138(1):19-25
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  • [Title] Solitary fibrous tumors of the pleura: results of surgical treatment and long-term prognosis.
  • OBJECTIVE: We sought to define the long-term outcome of surgically treated solitary fibrous tumors of the pleura.
  • Surgical resection included pulmonary wedge excision in 62 patients, lobectomy in 4 patients, segmentectomy in 2 patients, chest wall resection in 3 patients, isolated pleural resection in 7 patients, and chest wall resection with pulmonary wedge excision, lobectomy, or pneumonectomy in 3, 2, and 1 patients, respectively.
  • Histopathology was benign in 73 and malignant in 11 patients.
  • Nine (82%) patient with malignant tumors and 37 (54%) patients with benign tumors were symptomatic (P = .11).
  • The median tumor diameters for malignant and benign tumors were 12.0 and 4.5 cm, respectively (P = .001).
  • Median survival for patients with benign and malignant tumors was 284 and 55 months, respectively, and 5-year survival was 88.9% and 45.5%, respectively (P = .0005).
  • Eight (9.5%) patients had recurrent solitary fibrous tumors of the pleura.
  • Recurrences were malignant in 6 and benign in 2 patients.
  • CONCLUSION: Resection of benign solitary fibrous tumors of the pleura carries an excellent prognosis.
  • Both benign and malignant tumors can recur.

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  • (PMID = 19577049.001).
  • [ISSN] 1097-685X
  • [Journal-full-title] The Journal of thoracic and cardiovascular surgery
  • [ISO-abbreviation] J. Thorac. Cardiovasc. Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA090628-09; United States / NCI NIH HHS / CA / K12 CA090628; United States / NCI NIH HHS / CA / K12 CA090628-09
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS217187; NLM/ PMC2930758
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39. Leoncini G, Maio V, Puccioni M, Franchi A, De Giorgi V, Ucci F, Santucci M, Massi D: Orbital solitary fibrous tumor: a case report and review of the literature. Pathol Oncol Res; 2008 Jun;14(2):213-7
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  • [Title] Orbital solitary fibrous tumor: a case report and review of the literature.
  • Solitary fibrous tumor (SFT) is a rare spindle cell neoplasm typically arising in the pleura and involving the orbit as its most common extra-pleural location.
  • The tumor had a benign clinical course, with radical surgical excision followed by regression of the clinical symptoms.
  • We review the clinical, histopathological, and immunohistochemical features of the orbital SFT described so far, with particular emphasis on differential diagnosis with other spindle cell orbital neoplasms.
  • [MeSH-major] Orbital Neoplasms / diagnosis. Orbital Neoplasms / surgery. Solitary Fibrous Tumors / diagnosis. Solitary Fibrous Tumors / surgery
  • [MeSH-minor] Diagnosis, Differential. Exophthalmos / etiology. Female. Humans. Immunohistochemistry. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18493869.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 26
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40. Wang W, Quan CB, Li N, Wang XJ, Song JY, Jia SL, Lin MG: [Diagnosis of pleural cavity extraskeletal osteosarcoma: a case report and literature review]. Zhonghua Jie He He Hu Xi Za Zhi; 2010 Mar;33(3):202-5
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  • [Title] [Diagnosis of pleural cavity extraskeletal osteosarcoma: a case report and literature review].
  • OBJECTIVE: To describe the manifestations and diagnosis of pleural cavity extraskeletal osteosarcoma (ESO).
  • RESULTS: Chest CT of a middle-aged man revealed an enormous heterogeneous neoplasm, about 10.9 cm x 9.2 cm x 17.7 cm in size, in the left pleural cavity.
  • There was abundant calcification in the tumor, with signs of invasion into the diaphragm and the pleura.
  • Pleural effusion of the left thoracic cavity was also seen on the chest CT.
  • Osteosarcoma was confirmed by pathological study after surgical resection of the tumor.
  • Pleural cavity ESO is insidious and imaging studies often reveal a huge mass with abundant calcification.
  • The differential diagnosis includes benign and malignant diseases of the thorax.
  • [MeSH-major] Osteosarcoma. Pleural Cavity / pathology

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  • (PMID = 20450640.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
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41. Hayashi S, Kitada M, Ozawa K, Sato K, Hirata S, Tokusashi Y, Miyokawa N, Sasajima T: [Solitary fibrous tumor of the visceral pleura being suspected of chest wall origin: report of a case]. Kyobu Geka; 2009 Nov;62(12):1097-100
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  • [Title] [Solitary fibrous tumor of the visceral pleura being suspected of chest wall origin: report of a case].
  • We report a case of a solitary fibrous tumor (SFT) of the pleura which is suspected of chest wall tumor.
  • Chest X-ray and computed tomography showed a circumscribed mass of 35 x 22 mm in diameter arising from the parietal pleura.
  • The pedunculated tumor attached to the visceral pleura.
  • The tumor was diagnosed as a benign SFT in intraoperative diagnosis.
  • Long term clinical follow-up is recommended for patients with SFT, because the tumor recurrence and malignant transformation may occur in tumors with benign histological features.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / diagnosis. Thoracic Neoplasms / diagnosis. Thoracic Wall
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 19894579.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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42. Białas M, Szczepański W, Szpor J, Okoń K, Kostecka-Matyja M, Hubalewska-Dydejczyk A, Tomaszewska R: Adenomatoid tumour of the adrenal gland: a case report and literature review. Pol J Pathol; 2010;61(2):97-102
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  • [Title] Adenomatoid tumour of the adrenal gland: a case report and literature review.
  • Adenomatoid tumour (AT) is a rare, benign neoplasm of mesothelial origin, which usually occurs in the genital tract of both sexes.
  • Occasionally these tumours are found in extra genital locations such as heart, pancreas, skin, pleura, omentum, lymph nodes, retroperitoneum, intestinal mesentery and adrenal gland.
  • The tumour was an incidental finding during abdominal CT-scan for an unrelated condition.
  • We also present a review of the literature concerning adrenal gland AT and give possible differential diagnosis.
  • [MeSH-major] Adenomatoid Tumor / pathology. Adrenal Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Asymptomatic Diseases. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Incidental Findings. Male. Radiography, Abdominal. Tomography, X-Ray Computed

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  • (PMID = 20924994.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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43. Brauner M, Brillet PY: [Other malignant tumors of the pleura]. Rev Pneumol Clin; 2006 Apr;62(2):124-7
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  • [Title] [Other malignant tumors of the pleura].
  • Malignant tumors of the pleura are most often diffuse, nethertheless they are sometimes localized.
  • There is an overlap of the radiologic features of the benign and malignant pleural lesions.
  • The differential diagnosis may be difficult, even on histological sample.
  • Imaging allows the diagnosis of pleural involvement, suggests the malignity, guides percutaneous or thoracoscopic biopsies of the pleura, defines extent of the tumor and follows the course of the disease.
  • We will describe the malignant pleural tumors: pleural metastases, pleural involvement of broncho-pulmonary cancer, of lymphoma and leukaemia.
  • Then the rare pleural tumors will be described: malignant pleural fibroma, sarcoma, histiocytoma and hemangiopericytoma.
  • [MeSH-major] Pleural Neoplasms / pathology. Pleural Neoplasms / secondary

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  • (PMID = 16670666.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 12
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44. Hara M, Kume M, Oshima H, Shibamoto Y, Iida A, Mori Y, Nakamura A, Murase T: F-18 FDG uptake in a malignant localized fibrous tumor of the pleura. J Thorac Imaging; 2005 May;20(2):118-9
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  • [Title] F-18 FDG uptake in a malignant localized fibrous tumor of the pleura.
  • It was suggested that FDG-PET is helpful to know which parts of lesions are benign or malignant in patients with LFTP whose prognoses are usually difficult to predict.
  • [MeSH-major] Fluorodeoxyglucose F18. Neoplasms, Fibrous Tissue / diagnosis. Pleural Cavity / radionuclide imaging. Pleural Neoplasms / diagnosis. Radiopharmaceuticals
  • [MeSH-minor] Aged. Contrast Media / administration & dosage. Diagnosis, Differential. Female. Gadolinium DTPA. Humans. Magnetic Resonance Imaging / methods. Positron-Emission Tomography / methods. Thoracotomy / methods. Tomography, X-Ray Computed / methods

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  • (PMID = 15818213.001).
  • [ISSN] 0883-5993
  • [Journal-full-title] Journal of thoracic imaging
  • [ISO-abbreviation] J Thorac Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18; K2I13DR72L / Gadolinium DTPA
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45. Cabay RJ, Siddiqui NH, Alam S: Paratesticular papillary mesothelioma: a case with borderline features. Arch Pathol Lab Med; 2006 Jan;130(1):90-2
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  • Most often, mesotheliomas involve the serosal (serous) membranes of the pleura and peritoneum.
  • This combination of benign and semimalignant characteristics can make the diagnosis of such a lesion problematic.
  • We think that a diagnosis of "borderline papillary mesothelioma" can be considered for similar mesothelial proliferations to allow for a possible increase in diagnostic accuracy and provide an enhanced informational platform from which patients and clinicians can benefit.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Disease-Free Survival. Humans. Immunohistochemistry. Male. Middle Aged. Treatment Outcome

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  • (PMID = 16390245.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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46. Gossot D, Izquierdo RR, Girard P, Stern JB, Magdeleinat P: Thoracoscopic resection of bulky intrathoracic benign lesions. Eur J Cardiothorac Surg; 2007 Dec;32(6):848-51
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  • [Title] Thoracoscopic resection of bulky intrathoracic benign lesions.
  • BACKGROUND: Video-assisted thoracic surgery (VATS) is used for the diagnosis and treatment of some mediastinal lesions.
  • In 4 cases, the mass originated from the pleura, and in 10 cases from the mediastinum.
  • The final pathological diagnoses were the following: solitary fibrous tumours of the pleura (4), benign thymic cysts (2), teratomas (2), bronchogenic cyst (1), benign thymoma (1), pleuropericardial cyst (1) and benign neurogenic tumours (3).
  • It should be considered as a reliable alternate for tumours that are benign and most often asymptomatic.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Solitary Fibrous Tumor, Pleural / surgery. Thoracic Surgery, Video-Assisted / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Magnetic Resonance Imaging. Male. Mediastinal Cyst / diagnosis. Mediastinal Cyst / surgery. Middle Aged. Teratoma / diagnosis. Teratoma / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17913504.001).
  • [ISSN] 1010-7940
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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47. Liu CC, Wang HW, Li FY, Hsu PK, Huang MH, Hsu WH, Hsu HS, Wang LS: Solitary fibrous tumors of the pleura: clinicopathological characteristics, immunohistochemical profiles, and surgical outcomes with long-term follow-up. Thorac Cardiovasc Surg; 2008 Aug;56(5):291-7
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  • [Title] Solitary fibrous tumors of the pleura: clinicopathological characteristics, immunohistochemical profiles, and surgical outcomes with long-term follow-up.
  • BACKGROUND: Solitary fibrous tumors of the pleura (SFTP) are rare.
  • (2) to determine whether an immunohistochemical (IHC) study can be helpful in distinguishing benign from malignant SFTPs; and (3) to provide more complete information to better predict prognosis.
  • All cytologic studies of pleural effusion were negative for malignant cells.
  • Complete pleural resection with adequate safe margins was performed for all patients.
  • Eleven cases proved to have benign tumors and 4 had malignancies.
  • Conventional factors, including tumor size, tumor shape, symptomatic presentation, and histological type did not affect prognosis.
  • Interestingly, p16 expression was significantly associated with tumor recurrence ( P = 0.009).
  • CONCLUSION: Complete pleural resection with adequate safe margins can achieve satisfactory outcomes in a majority of cases, but long-term follow-up for all patients is recommended due to the potential for late tumor recurrence.
  • However, IHC studies of the CD-34 and bcl-2 biomarkers can be important for further differential diagnosis, and p16 expression can be used to predict tumor recurrence.
  • [MeSH-major] Biomarkers, Tumor / analysis. Immunohistochemistry. Pulmonary Surgical Procedures. Solitary Fibrous Tumor, Pleural
  • [MeSH-minor] Aged. Diagnosis, Differential. Disease-Free Survival. Female. Humans. Kaplan-Meier Estimate. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors. Treatment Outcome

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  • (PMID = 18615377.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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48. Takagi M, Kuwano K, Watanabe K, Akiba T: A case of recurrence and rapid growth of pleural solitary fibrous tumor 8 years after initial surgery. Ann Thorac Cardiovasc Surg; 2009 Jun;15(3):178-81
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  • [Title] A case of recurrence and rapid growth of pleural solitary fibrous tumor 8 years after initial surgery.
  • A 69-year-old woman underwent resection of a solitary fibrous tumor (SFT) of the left pleura in April 1997 and of locally recurrent SFT in the left thoracic cavity in September 2003.
  • A postoperative follow-up chest CT scan in March 2005 revealed pleural thickening at two sites of the left thoracic cavity.
  • The two resected tumors were benign SFT, and were diagnosed as locally recurrent SFT in the left thoracic cavity.
  • It has been reported that despite its benign histopathology, pleural SFT recurs more than once after surgery, and the interval between recurrences tends to shorten from the second recurrence.
  • In this patient, the tumor recurred twice and showed a rapidly enlarging tendency at the time of the second recurrence, suggesting the need for careful follow-up at short intervals.
  • [MeSH-major] Neoplasm Recurrence, Local. Pleural Neoplasms / surgery. Pulmonary Surgical Procedures. Solitary Fibrous Tumor, Pleural / surgery

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  • (PMID = 19597394.001).
  • [ISSN] 2186-1005
  • [Journal-full-title] Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
  • [ISO-abbreviation] Ann Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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49. Paiva Nunes A, Mendes I, Godinho T, Lourenço I, Jordão A, Gorjão Clara J: [Solitary fibrous tumor of the pleura]. Rev Port Cir Cardiotorac Vasc; 2007 Oct-Dec;14(4):203-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary fibrous tumor of the pleura].
  • [Transliterated title] Tumor fibroso solitário da pleura.
  • Solitary fibrous tumors of the pleura are rare tumors originating from the mesenchymal cells of the submesothelial tissue of the pleura.
  • In half of the cases, the neoplasm presents as an asymptomatic mass, often with quite large dimensions.
  • It is a benign tumor in 80% of the cases and even when considered malignant has a good prognosis if totally removed.
  • We present the case of a 78-year-old female, who was evaluated for lower respiratory infection, in whom the diagnosis of Giant Solitary Fibrous Tumor of the Pleura was made.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural

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  • (PMID = 18408817.001).
  • [ISSN] 0873-7215
  • [Journal-full-title] Revista portuguesa de cirurgia cardio-torácica e vascular : órgão oficial da Sociedade Portuguesa de Cirurgia Cardio-Torácica e Vascular
  • [ISO-abbreviation] Rev Port Cir Cardiotorac Vasc
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Portugal
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50. Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ, Hatabu H: Morphologic and functional imaging of malignant pleural mesothelioma. Eur J Radiol; 2007 Dec;64(3):356-66
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  • [Title] Morphologic and functional imaging of malignant pleural mesothelioma.
  • Malignant pleural mesothelioma (MPM) is an aggressive tumor that arises from the pleura and frequently extends to adjacent structures.
  • Major findings include nodular pleural thickening, unilateral pleural effusion, and tumor invasion of adjacent structures.
  • Because of its excellent contrast resolution, MRI is superior to CT, both in the differentiation of malignant from benign pleural disease, and in the assessment of chest wall and diaphragmatic involvement.
  • Perfusion MRI is the most promising technique for the assessment of the tumor microvasculature.
  • It has been shown that FDG-PET is useful for the differentiation of benign from malignant lesions, for staging and monitoring metabolic response to therapy against MPM, and that it has prognostic value.
  • An initial report on PET/CT imaging of MPM has shown increased accuracy of overall staging, improving the assessment of tumor resectability.
  • [MeSH-major] Diagnostic Imaging / methods. Mesothelioma / diagnosis. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Humans. Magnetic Resonance Imaging / methods. Neoplasm Staging. Neovascularization, Pathologic / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods


51. Kayser K, Hoshang SA, Metze K, Goldmann T, Vollmer E, Radziszowski D, Kosjerina Z, Mireskandari M, Kayser G: Texture- and object-related automated information analysis in histological still images of various organs. Anal Quant Cytol Histol; 2008 Dec;30(6):323-35
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  • MATERIALS: A generalized algorithm was developed that permits the evaluation of diagnosis-associated image features obtained from hematoxylin-eosin-stained histopathologic slides.
  • The procedure was tested for screening of tumor tissue vs. tumor-free tissue in 1,442 cases of various organs.
  • Tissue samples studied include colon, lung, breast, pleura, stomach and thyroid.
  • RESULTS: The accuracy of automated crude classification was between 95% and 100% based upon a learning set of 10 cases per diagnosis class.
  • The algorithm can also distinguish between benign and malignant tumors of colon, between epithelial mesothelioma and pleural carcinomatosis or between different common pulmonary carcinomas.
  • It is a promising technique that can assist tissue-based diagnosis and be expanded to virtual slide evaluation.

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  • (PMID = 19160697.001).
  • [ISSN] 0884-6812
  • [Journal-full-title] Analytical and quantitative cytology and histology
  • [ISO-abbreviation] Anal. Quant. Cytol. Histol.
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Miyamoto H, Molena DA, Schoeniger LO, Haodong Xu: Solitary fibrous tumor of the pancreas: a case report. Int J Surg Pathol; 2007 Jul;15(3):311-4
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  • [Title] Solitary fibrous tumor of the pancreas: a case report.
  • Solitary fibrous tumor (SFT) is an unusual mesenchymal neoplasm that most often arises in the pleura; however, it has recently been described in a number of extrapleural sites.
  • This report describes an extremely rare case of a benign SFT arising in the pancreas.
  • An endocrine tumor was clinically suspected.
  • Microscopically, the tumor was composed of bland uniform spindle cells arranged between collagen bundles.
  • Based on the light microscopic morphology and immunohistochemical staining profile, the diagnosis of SFT was rendered.
  • [MeSH-major] Neoplasms, Fibrous Tissue / diagnosis. Pancreatic Neoplasms / diagnosis

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  • (PMID = 17652547.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2
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53. Woenckhaus M, Grepmeier U, Werner B, Schulz C, Rockmann F, Wild PJ, Röckelein G, Blaszyk H, Schuierer M, Hofstaedter F, Hartmann A, Dietmaier W: Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology. J Mol Diagn; 2005 Oct;7(4):517-24
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  • [Title] Microsatellite analysis of pleural supernatants could increase sensitivity of pleural fluid cytology.
  • Pleural effusions may result from various inflammatory, hemodynamic, or neoplastic conditions.
  • A common diagnostic problem lies in distinguishing malignant from benign pleural effusions using routine cytological evaluation.
  • We studied pleural fluid samples obtained from 14 patients with histologically confirmed malignancy and from 6 patients with benign pleural effusions using 12 microsatellite markers from 8 different chromosomal regions.
  • Supernatants and cellular sediments of all 20 pleural fluid samples were analyzed.
  • Microsatellite analyses of pleural fluid supernatants showed genetic alterations in tumor patients only.
  • However, 50% of pleural effusions that were considered negative for malignancy by routine cytological analysis showed either loss of heterozygosity or microsatellite instability.
  • The sensitivity of pleural fluid examination rose to 79% when routine cytological assessment was supplemented by molecular studies.
  • Our data suggest that microsatellite analysis increases the sensitivity of cytological pleural fluid examination in assessing potential malignancy and that combining cytological and molecular methods may improve yield and certainty in diagnostically challenging cases.
  • [MeSH-major] Body Fluids / metabolism. Diagnostic Tests, Routine / methods. Microsatellite Repeats / genetics. Pleura / metabolism. Pleura / pathology
  • [MeSH-minor] Aged. Aged, 80 and over. Female. Genetic Markers / genetics. Humans. Loss of Heterozygosity / genetics. Male. Middle Aged. Neoplasms / diagnosis. Neoplasms / genetics. Neoplasms / pathology. Sensitivity and Specificity

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  • (PMID = 16237222.001).
  • [ISSN] 1525-1578
  • [Journal-full-title] The Journal of molecular diagnostics : JMD
  • [ISO-abbreviation] J Mol Diagn
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Genetic Markers
  • [Other-IDs] NLM/ PMC1888495
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54. Lu C, Ji Y, Shan F, Guo W, Ding J, Ge D: Solitary fibrous tumor of the pleura: an analysis of 13 cases. World J Surg; 2008 Aug;32(8):1663-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the pleura: an analysis of 13 cases.
  • BACKGROUND: Solitary fibrous tumor of the pleura is a rare soft-tissue tumor.
  • In search of appropriate diagnosis and treatment methods, we present our experience with 13 patients.
  • Seven tumors were malignant and the other six were benign.
  • Immunohistochemical staining showed nestin was positive in three malignant solitary fibrous tumors of pleura (3/7), which were negative for CD34.
  • CONCLUSION: Ultrasonography-guided core needle biopsy combined with immunohistochemical analysis might be a safe and rapid method to provide a confirmatory diagnosis before resection.
  • We speculate that CD34-negative and nestin-positive might be a malignant marker for solitary fibrous tumor of pleura.
  • [MeSH-major] Neoplasms, Fibrous Tissue / diagnosis. Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / diagnosis. Pleural Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Biopsy, Needle / methods. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Metastasis. Radiography, Thoracic. Thoracic Surgery, Video-Assisted. Tomography, X-Ray Computed. Ultrasonography, Interventional

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  • (PMID = 18427887.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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55. Stević R, Jovanović D, Mandarić M, Pesut D, Masulović D, Stosić-Opinćal T, Adzić T, Vasić N: [Radiologic manifestation of primary pleural tumors]. Acta Chir Iugosl; 2009;56(4):63-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Radiologic manifestation of primary pleural tumors].
  • OBJECTIVES: To show the radiological manifestations of primary pleural tumors.
  • PATIENTS AND METHODS: we carried out a retrospective analysis of radiological findings in 62 patients with primary malignant tumor of pleura.
  • Malignant tumors were present in 92.7% of the patients and benign ones in 7.2%.
  • The most common malignant tumor was mesothelioma (85.4%), and solitary fibrous tumor prevailed among benign tumors (9.7%).
  • Diffuse malignant mesothelioma manifested on computed tomography (CT) as a pleural thickening and effusion in 67.4% of the patients, tumors and effusion in 11.7%, and only as an effusion in 9.8% cases.
  • Thickening of the pleura appeared diffuse in 54% of patients and most often it had nodular pattern.
  • Both localized malignant and all benign tumors presented as tumor-like changes with the signs of necrosis in 50%.
  • CONCLUSION: The imaging methods have a key role in the diagnosis of pleural tumors.
  • CT shows different morphologic features of pleural lesions that have been established as a useful tool for differentiating malignant from benign disease.
  • However, magnetic resonance is preferred imaging method for assessing the extent and resectability of pleural tumors.
  • [MeSH-major] Pleural Neoplasms / radiography

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  • (PMID = 20419999.001).
  • [ISSN] 0354-950X
  • [Journal-full-title] Acta chirurgica Iugoslavica
  • [ISO-abbreviation] Acta Chir Iugosl
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia
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56. Chatti K, Nouira K, Ben Reguigua M, Bedioui H, Oueslati S, Laabidi B, Alaya M, Ben Abdallah N: [Solitary fibrous tumor of the pancreas. A case report]. Gastroenterol Clin Biol; 2006 Feb;30(2):317-9
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  • [Title] [Solitary fibrous tumor of the pancreas. A case report].
  • [Transliterated title] Tumeur fibreuse solitaire du pancréas. A propos d'un cas.
  • Solitary fibrous tumour (SFT), a rare mesenchymal neoplasm usually arising from the pleura, may also occur in many other extra pleural sites.
  • This report describes the case of a benign SFT of the pancreas occurring in a 41-year-old man who presented with a solid epigastric mass.
  • Surgical resection of the tumour was performed, and the patient died from postoperative complications.
  • [MeSH-major] Neoplasms, Fibrous Tissue / diagnosis. Pancreatic Neoplasms / diagnosis

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  • (PMID = 16565671.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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57. Carretta A, Bandiera A, Melloni G, Ciriaco P, Arrigoni G, Rizzo N, Negri G, Zannini P: Solitary fibrous tumors of the pleura: Immunohistochemical analysis and evaluation of prognostic factors after surgical treatment. J Surg Oncol; 2006 Jul 1;94(1):40-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura: Immunohistochemical analysis and evaluation of prognostic factors after surgical treatment.
  • BACKGROUND AND OBJECTIVES: Solitary fibrous tumors of the pleura (SFTP) are rare neoplasms with unusual histological and clinical features.
  • Although surgery is the treatment of choice for SFTP, tumor recurrence may occur after complete resection, even in tumors with benign histological features.
  • Mean tumor size was 10 cm.
  • Histological features were benign in 16 patients and malignant in 2.
  • A higher incidence of tumor recurrence was observed when SFTP originated from the parietal pleura, had malignant histological features and a lower expression of progesterone receptors (P < 0.05).
  • [MeSH-major] Fibroma / pathology. Fibroma / surgery. Neoplasm Recurrence, Local / pathology. Pleural Neoplasms / pathology. Pleural Neoplasms / surgery

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  • [Copyright] Copyright 2006 Wiley-Liss, Inc.
  • (PMID = 16788942.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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58. Pinedo-Onofre JA, Robles-Pérez E, Peña-Mirabal ES, Hernández-Carrillo JA, Téllez-Becerra JL: Giant solitary fibrous tumor of the pleura. Cir Cir; 2010 Jan-Feb;78(1):31-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant solitary fibrous tumor of the pleura.
  • BACKGROUND: Solitary fibrous tumor is the second primary malignancy of the pleura and can reach up to 39 cm in diameter; however, to be referred to as 'giant' it must occupy at least 40% of the affected hemithorax.
  • Although this tumor usually shows a benign behavior, malignancy criteria have been described.
  • METHODS: We performed a descriptive, observational, longitudinal, and retrospective study from 2002 to 2006 on patients who underwent surgery with a diagnosis of giant solitary fibrous tumor of the pleura.
  • Accurate diagnosis is critical because surgical resection involves a potential cure; however, long-term follow-up is mandatory.
  • Preoperative embolization is recommended due to tumor size.
  • [MeSH-major] Pleural Neoplasms / surgery. Solitary Fibrous Tumors / surgery

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  • (PMID = 20226126.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] eng; spa
  • [Publication-type] Journal Article
  • [Publication-country] Mexico
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59. Sung SH, Chang JW, Kim J, Lee KS, Han J, Park SI: Solitary fibrous tumors of the pleura: surgical outcome and clinical course. Ann Thorac Surg; 2005 Jan;79(1):303-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura: surgical outcome and clinical course.
  • BACKGROUND: The aim of this study was to define more precisely the surgical outcome and clinical course of solitary fibrous tumors of the pleura.
  • METHODS: We conducted a retrospective review of the clinical records of patients who had undergone surgical resection for benign and malignant solitary fibrous tumors of the pleura during a 10-year period (1993 to 2003).
  • Thirty-six patients (57.1%) were symptomatic at the time of diagnosis.
  • Forty-four cases (69.8%) were benign and 19 (30.2%) were malignant.
  • Symptomatic presentation and the impression of a nonpleural tumor by imaging study were found to be related to a malignant pathologic diagnosis.
  • The radiologic impression of solitary fibrous tumors of the pleura was also related to mass excision only.
  • [MeSH-major] Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / surgery. Thoracic Surgery, Video-Assisted. Thoracotomy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biopsy, Fine-Needle. Child. Child, Preschool. Female. Humans. Incidental Findings. Life Tables. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Sternum / surgery. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 15620963.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 17
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60. Wang H, Jiang G, Wang D, Liu J, Wang J: [mRNA expression of MAGE genes in benign and malignant pleural effusion]. Zhongguo Fei Ai Za Zhi; 2006;9(4):329-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [mRNA expression of MAGE genes in benign and malignant pleural effusion].
  • BACKGROUND: Melanoma antigen genes (MAGE) are tumor specific genes.
  • The aim of this study is to explore the feasibility of MAGE genes detection as a diagnostic method for malignant pleural effusion.
  • METHODS: The expression of MAGE-1, -2, -3 and -4 mRNA was detected in 18 benign and 22 malignant pleural effusion samples by RT-PCR.
  • RESULTS: No MAGE gene expressed in the 18 cases of benign pleural effusion.
  • Out of the 22 cases of malignant pleural effusion, 8 cases were positive by cytological examination, who all showed positive expression of MAGA genes; in the other 14 patients who were positive by pleural biopsy but negative by cytological examination, 11 cases showed positive expression of MAGE genes in both the pleural effusion and pleura samples, while the other 3 cases showed negative MAGE expression in both the pleural effusion and pleura samples.
  • CONCLUSIONS: Detection of MAGE genes in pleural effusion may be an effective method in the differential diagnosis of benign and malignant pleural effusion.

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  • (PMID = 21176448.001).
  • [ISSN] 1009-3419
  • [Journal-full-title] Zhongguo fei ai za zhi = Chinese journal of lung cancer
  • [ISO-abbreviation] Zhongguo Fei Ai Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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61. Szkorupa M, Klein J, Bohanes T, Neoral C, Chudácek J: [Solitary fibrous tumor of pleural cavity]. Rozhl Chir; 2010 Dec;89(12):750-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary fibrous tumor of pleural cavity].
  • [Transliterated title] Solitární fibrózní tumor pleurální dutiny.
  • INTRODUCTION: Solitary fibrous pleural tumor (SFT) is, in most cases, a benign tumor arising from mesenchymal cells.
  • A malignant version of the tumor is rare and its histopathological evaluation is quite difficult.
  • Usually, SFT affects visceral, as well as parietal pleura, most commonly in a form of a pedunculated tumor.
  • Adjuvant therapy is indicated in malignant varieties of the tumor, however, its outcome is uncertain.
  • SUBJECTS AND METHODS: The authors present a group of 11 patients with solitary fibrous pleural tumors, who were operated at the Ist Faculty Hospital Surgical Clinic of the LF UP (Medical Faculty of the Palacky University) in Olomouc from 2006 to 2009.
  • CONCLUSION: Solitary pleural tumors are fairly rare tumors arising from fibroblastic cells, Its biological characteristics is uncertain and, in some cases, is difficult to assess based on immunohistochemical, as well as morphological indicators.
  • The treatment is surgical--removal of the tumor as far as the healthy tissue.
  • Adjuvant therapy is indicated in malignant varieties of the tumor.
  • SFT relaps rate is fairly high, depending on the tumor biological characteristics and its morphological features.
  • [MeSH-major] Pleural Neoplasms. Solitary Fibrous Tumor, Pleural

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  • (PMID = 21404515.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] cze
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Czech Republic
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62. Zhou X, Yi XH, Kong J: [The clinicopathological features and surgical treatment of solitary fibrous tumor of the pleura]. Zhonghua Jie He He Hu Xi Za Zhi; 2007 Apr;30(4):284-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The clinicopathological features and surgical treatment of solitary fibrous tumor of the pleura].
  • OBJECTIVE: To investigate the clinicopathological features and surgical treatment of solitary fibrous tumor of the pleura (SFTP).
  • Five cases had pleural effusion.
  • Eight cases received tumor resection by wedge resection of the lung, and the other 3 patients by middle and lower lobe resection, lower lobe resection and chest wall tumor resection, respectively.
  • Nine tumors were located in the visceral pleura, 1 tumor below the visceral pleura, and 1 tumor in parietal pleura.
  • There were abundant gross collagenous fibers and thick-walled blood vessels around tumor cells.
  • The tumor cells were stained with vimentin (100%, 11/11), CD(34) (100%, 11/11), CD(99) (63.6%, 7/11), and bcl-2 (63.6%, 7/11), but no expression of CD(31).
  • Of the 11 cases, 9 were histologically diagnosed as benign SFTP, 1 as cell-abundant type of SFTP, and another as malignant SFTP.
  • CONCLUSIONS: SFTP should be considered when chest X-ray and CT showed single nodule or mass in the pleura.
  • The diagnosis is based on examination of histopathology and immunohistochemistry.
  • For a tumor with a diameter les than 5 cm, resection by VATS or VATS plus small thoracotomy is a good surgical procedure.
  • [MeSH-major] Neoplasms, Fibrous Tissue / pathology. Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / pathology. Pleural Neoplasms / surgery

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  • (PMID = 17651613.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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63. Toporcer T, Belák J, Böör A, Kudlác M, Lakyová L, Radonak J: [Giant solitary fibrous tumor of the pleura--case report]. Rozhl Chir; 2009 Mar;88(3):97-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Giant solitary fibrous tumor of the pleura--case report].
  • [Transliterated title] Obrovský solitárny fibrózny tumor pleury--kazuistika.
  • Solitary fibrous tumors of the pleura are rare malignant pathological findings, accounting for only 5% of all pleural neoplasms.
  • The authors performed right-sided thoracotomy and removed an encapsulated solid tumor measuring 24 x 16 x 13.5 cm and weighting 2850 grams from the thoracic cavity.
  • Benign solitary fibrous tumor was diagnosed on histology.
  • The postoperative course was complicated by bleeding into the pleural cavity, which was managed conservatively and did not require subsequent surgical revision.
  • The aim of the study is to draw attention to this tumorous disorder of the pleura - the solitary fibrous tumor.
  • [MeSH-major] Pleural Neoplasms / pathology. Solitary Fibrous Tumor, Pleural / pathology

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  • (PMID = 19526938.001).
  • [ISSN] 0035-9351
  • [Journal-full-title] Rozhledy v chirurgii : měsíčník Československé chirurgické společnosti
  • [ISO-abbreviation] Rozhl Chir
  • [Language] slo
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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64. Granville L, Laga AC, Allen TC, Dishop M, Roggli VL, Churg A, Zander DS, Cagle PT: Review and update of uncommon primary pleural tumors: a practical approach to diagnosis. Arch Pathol Lab Med; 2005 Nov;129(11):1428-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Review and update of uncommon primary pleural tumors: a practical approach to diagnosis.
  • OBJECTIVE: We address the current classifications and new changes regarding uncommon primary pleural tumors.
  • Primary pleural tumors are divided according to their behavior and are discussed separately as benign tumors, tumors of low malignant potential, and malignant neoplasms.
  • DATA SOURCES: Current literature concerning primary pleural neoplasms was collected and reviewed.
  • STUDY SELECTION: Studies emphasizing clinical, radiological, or pathologic findings of primary pleural neoplasms were obtained.
  • DATA EXTRACTION: Data deemed helpful to the general surgical pathologist when confronted with an uncommon primary pleural tumor was included in this review.
  • (1) benign, (2) low malignant potential, and (3) malignant.
  • A practical approach to the diagnosis of these neoplasms in surgical pathology specimens is offered.
  • The differential diagnosis, including metastatic pleural neoplasms, is also briefly addressed.
  • CONCLUSIONS: Uncommon primary pleural neoplasms may mimic each other, as well as mimic metastatic cancers to the pleura and diffuse malignant mesothelioma.
  • Correct diagnosis is important because of different prognosis and treatment implications for the various neoplasms.
  • [MeSH-major] Medical Oncology / methods. Mesothelioma / pathology. Neoplasm Metastasis / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Pleura / pathology

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  • (PMID = 16253024.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Review
  • [Publication-country] United States
  • [Number-of-references] 131
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65. Stanić V, Vulović T, Ilić S, Stamenović D: Solitary fibrous tumors of the pleura. J BUON; 2006 Apr-Jun;11(2):241-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura.
  • Two cases of female patients with solitary fibrous tumor of the pleura are described.
  • Transthoracic needle biopsy of the masses showed benign fibrous tissue.
  • The tumors arose from the visceral pleura, were peduncular, appeared well-circumscribed with exterior surface smooth, firm and multinodular.
  • The pathological diagnosis was benign solitary fibrous tumor of the pleura.
  • [MeSH-major] Fibroma / pathology. Pleural Neoplasms / pathology

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  • (PMID = 17318979.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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66. Kyriafinis G, Constantinidis J, Karkavelas G, Triaridis S, Daniilidis J: [Solitary fibrous tumor of the nose and paranasal sinuses]. HNO; 2006 Dec;54(12):962-6
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  • [Title] [Solitary fibrous tumor of the nose and paranasal sinuses].
  • [Transliterated title] Solitärer fibröser Tumor der Nasenhaupt- und Nasennebenhöhlen.
  • OBJECTIVE: The solitary fibrous tumor is an uncommon, benign lesion with a mesenchymal origin which arises most commonly from the pleura and, in extremely rare cases, from the mucosa of the nose and paranasal sinuses.
  • PATIENT AND METHODS: We describe a case of solitary fibrous tumor in the nasal cavity with an extension into both ethmoid sinuses and destruction of the nasal septum in a 64-year-old woman presenting with nasal obstruction and frontal headache.
  • In the histopathologic examination and by immunohistochemistry, the tumor was composed of spindle cells and nodular collagen, and was confirmed as a solitary fibrous tumor.
  • CONCLUSIONS: Solitary fibrous tumor should be included in diagnostic considerations in patients with sinonasal masses, especially in cases with the appearance of spindle cells.

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  • (PMID = 16477466.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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67. Chua TC, Yan TD, Morris DL: Surgical biology for the clinician: peritoneal mesothelioma: current understanding and management. Can J Surg; 2009 Feb;52(1):59-64
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  • Mesothelioma is an asbestos-related tumour.
  • Mesothelioma in the thorax occurs on the pleura and is known as pleural mesothelioma.
  • Early diagnosis of peritoneal mesothelioma is often difficult because the early symptoms are often overlooked as being a benign ailment of the gastrointestinal tract.
  • Therefore, diagnosis often occurs at an advanced stage when disease is widespread throughout the peritoneal cavity.
  • [MeSH-major] Mesothelioma / diagnosis. Mesothelioma / therapy. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / therapy
  • [MeSH-minor] Asbestos / adverse effects. Biomarkers, Tumor. Chemotherapy, Cancer, Regional Perfusion. Diagnostic Imaging. Endoscopy, Gastrointestinal. Humans. Hyperthermia, Induced

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  • (PMID = 19234654.001).
  • [ISSN] 1488-2310
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 1332-21-4 / Asbestos
  • [Number-of-references] 54
  • [Other-IDs] NLM/ PMC2637623
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68. Kristensen PL, Petersen RH, Hansen PB: [Spontaneous hemothorax from a fibrous pleural tumour in an expectant father. Is the delivery room a dangerous place for men?]. Ugeskr Laeger; 2007 Apr 2;169(14):1325-6
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  • [Title] [Spontaneous hemothorax from a fibrous pleural tumour in an expectant father. Is the delivery room a dangerous place for men?].
  • [Transliterated title] Spontan haemothorax fra en fibrøs pleural tumor hos en vordende far. Er fødestuer farlige for maend?
  • An X-ray of the chest showed a tumour in the left side of the mediastinum and a large left pleural effusion.
  • During the operation a benign solitary fibrous tumour was radically resected from the pleura and a large hemothorax was removed.
  • This unusual presentation with severe bleeding from a pleural tumour was most probably initiated by the expectant father's excitement during his wife's labour.
  • [MeSH-major] Hemothorax / etiology. Neoplasms, Fibrous Tissue / complications. Pleural Neoplasms / complications
  • [MeSH-minor] Adult. Age of Onset. Diagnosis, Differential. Emotions. Fathers / psychology. Humans. Male. Risk Factors

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  • (PMID = 17437697.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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69. Robinson LA: Solitary fibrous tumor of the pleura. Cancer Control; 2006 Oct;13(4):264-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the pleura.
  • BACKGROUND: The solitary fibrous tumor of the pleura (SFTP) is a rare primary tumor arising from mesenchymal cells in the areolar tissue subjacent to the mesothelial-lined pleura.
  • The tumor appears to be unrelated to malignant pleural mesothelioma, the most common primary tumor of the pleura.
  • METHODS: In just over half of these cases, the neoplasm presents as an asymptomatic mass, is often quite large, and is benign in 78% to 88% of patients.
  • The initial evaluation and diagnosis, tumor classification, surgical treatment, results of therapy, and long-term prognosis are reviewed, based on a selective review of the literature from MEDLINE beginning 1980.
  • RESULTS: Complete en bloc surgical resection is the preferred treatment of benign and malignant varieties of the tumor.
  • The pedunculated tumors attached to the visceral pleura can be effectively treated with a wedge resection of lung.
  • CONCLUSIONS: Benign SFTP has a high cure rate and an 8% local recurrence rate that is usually amenable to curative re-excision.
  • The majority of patients with recurrent disease die of the tumor within 2 years.
  • [MeSH-major] Neoplasms, Fibrous Tissue / diagnosis. Neoplasms, Fibrous Tissue / therapy. Pleural Neoplasms / diagnosis. Pleural Neoplasms / therapy
  • [MeSH-minor] Diagnosis, Differential. Humans. Incidence. Neoadjuvant Therapy. Thoracic Surgical Procedures. Tomography, X-Ray Computed. United States / epidemiology

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  • (PMID = 17075563.001).
  • [ISSN] 1073-2748
  • [Journal-full-title] Cancer control : journal of the Moffitt Cancer Center
  • [ISO-abbreviation] Cancer Control
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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70. Minato H, Nojima T, Kurose N, Kinoshita E: Adenomatoid tumor of the pleura. Pathol Int; 2009 Aug;59(8):567-71
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  • [Title] Adenomatoid tumor of the pleura.
  • A case of adenomatoid tumor of the pleura is reported, and its differential diagnosis from benign and malignant pleural lesions is discussed.
  • A small pleural nodule was incidentally found during a thoracic operation in a 54-year-old woman with esophageal cancer.
  • A 7 mm, circumscribed tumor had characteristic features of adenomatoid tumor.
  • The tumor was composed of an aggregation of irregularly shaped tubulocystic spaces with fibrous stoma.
  • On immunohistochemistry the tumor cells were positive for AE1/AE3, CAM5.2, vimentin, cytokeratin 5/6, D2-40, calretinin, thrombomodulin, and WT-1, but negative for CEA, Leu M1 (CD15), thyroid transcription factor-1, epithelial membrane antigen, desmin, glucose transporter-1 (GLUT-1), CD31, and CD34.
  • Adenomatoid tumor of the pleura is rare, and the pathogenesis has not been elucidated.
  • Recognition of these benign mesothelial lesions in the pleura is important to avoid misdiagnosis.
  • [MeSH-major] Adenomatoid Tumor / pathology. Neoplasms, Multiple Primary / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Dermatomyositis / complications. Esophageal Neoplasms / complications. Esophageal Neoplasms / pathology. Female. Humans. Immunohistochemistry. Incidental Findings. Liver Cirrhosis, Biliary / complications. Middle Aged

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  • (PMID = 19627540.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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71. Santos RS, Haddad R, Lima CE, Liu YL, Misztal M, Ferreira T, Boasquevisque CH, Luketich JD, Landreneau RJ: Patterns of recurrence and long-term survival after curative resection of localized fibrous tumors of the pleura. Clin Lung Cancer; 2005 Nov;7(3):197-201
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  • [Title] Patterns of recurrence and long-term survival after curative resection of localized fibrous tumors of the pleura.
  • BACKGROUND: Localized fibrous tumors of the pleura (LFTPs) are uncommon thoracic neoplasms with variable malignant potential that were previously classified as benign presentation of mesothelioma.
  • The malignant potential of the tumor was estimated through histologic assessment of the degree of cellularity, mitotic activity, and nuclear pleomorphism.
  • Ipsilateral pleural recurrence remote to the original tumor site occurred in 6 of these patients with malignant microscopic characteristics at a mean of 9 months after resection.
  • There have been no recurrences among the other 27 patients with benign histologic features, and 31 patients remain alive at a median follow-up of 34.5 months.
  • [MeSH-major] Neoplasm Recurrence, Local. Neoplasms, Fibrous Tissue / surgery. Pleura / surgery. Pleural Neoplasms / surgery

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  • (PMID = 16354315.001).
  • [ISSN] 1525-7304
  • [Journal-full-title] Clinical lung cancer
  • [ISO-abbreviation] Clin Lung Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Davini F, Gonfiotti A, Vaggelli L, De Francisci A, Gigli P, Janni A: Thoracoscopic localization techniques for patients with solitary pulmonary nodule: radioguided surgery versus hookwire localization. J Cardiovasc Surg (Torino); 2006 Jun;47(3):355-9
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  • Inclusion criteria was: a maximum nodule diameter of less than 3 cm and a maximum distance from the visceral pleura of 3 cm.
  • RESULTS: The frozen section revealed a primitive pulmonary tumor in 13 cases, intestinal adenocarcinoma metastasis in 3 cases and renal cancer metastasis in 1 case.
  • The remaining 13 cases were pathologically benign: sarcoidosis in 6 cases, hamartochondroma in 3 cases, scleroanthracosis in 2 cases and tuberculoma in 2 cases.
  • CONCLUSION: On the basis of our experience, the conclusion is drawn that this methods has been proven efficacious in the diagnosis of SPN, and video-assisted thoracoscopy allows for the removal of pulmonary nodules without complications.

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  • (PMID = 16760874.001).
  • [ISSN] 0021-9509
  • [Journal-full-title] The Journal of cardiovascular surgery
  • [ISO-abbreviation] J Cardiovasc Surg (Torino)
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] Italy
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73. Santambrogio L, Nosotti M, Palleschi A, Rosso L, Tosi D, De Simone M, Ciulla MM, Maggioni M, Cioffi U: Solitary fibrous tumor of the pleura presenting with syncope episodes when coughing. World J Surg Oncol; 2008;6:86
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  • [Title] Solitary fibrous tumor of the pleura presenting with syncope episodes when coughing.
  • BACKGROUND: Solitary fibrous tumor of the pleura is a rarely encountered clinical entity which may have different clinical pictures.
  • Although the majority of these neoplasms have a benign course, the malignant form has also been reported.
  • Hystological examination of the surgical specimen showed an encapsulated mass measuring 12 x 11.5 x 6 cm consistent with a solitary fibrous tumor of the pleura.
  • [MeSH-major] Cough / etiology. Nerve Compression Syndromes / etiology. Phrenic Nerve. Solitary Fibrous Tumor, Pleural / complications. Syncope / etiology

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  • (PMID = 18713458.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2531110
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74. Balduyck B, Lauwers P, Govaert K, Hendriks J, De Maeseneer M, Van Schil P: Solitary fibrous tumor of the pleura with associated hypoglycemia: Doege-Potter syndrome: a case report. J Thorac Oncol; 2006 Jul;1(6):588-90
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  • [Title] Solitary fibrous tumor of the pleura with associated hypoglycemia: Doege-Potter syndrome: a case report.
  • Tumor-associated hypoglycemia as a paraneoplastic phenomenon is a well-known entity and is referred to as Doege-Potter syndrome.
  • All investigations proved to be normal, except for a chest x-ray, which showed a large pleural mass.
  • On transthoracic puncture, a tumor of pleural origin was diagnosed.
  • This tumor, presenting as a large, well-circumscribed encapsulated mass, was removed by thoracotomy.
  • On pathologic examination, the diagnosis of a solitary fibrous tumor with benign characteristics was made.
  • Solitary fibrous tumors are localized tumors of the pleura with an unpredictable behavior.
  • [MeSH-major] Neoplasms, Fibrous Tissue / pathology. Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / pathology. Pleural Neoplasms / surgery. Pneumonectomy / methods
  • [MeSH-minor] Aged. Biopsy, Needle. Bronchoscopy. Follow-Up Studies. Humans. Immunohistochemistry. Male. Neoplasm Staging. Radiography, Thoracic. Thoracotomy / methods. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17409923.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Liu J, Cai C, Wang D, Chen H, Cheng L, Shao W, Li S, Guan Y, Gu Y, He J: Video-assisted thoracoscopic surgery (VATS) for patients with solitary fibrous tumors of the pleura. J Thorac Oncol; 2010 Feb;5(2):240-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Video-assisted thoracoscopic surgery (VATS) for patients with solitary fibrous tumors of the pleura.
  • OBJECTIVES: To present our experience of video-assisted thoracoscopic surgery (VATS) for patients with solitary fibrous tumors of the pleura (SFTPs) and to discuss the treatment of choice of such neoplasms.
  • There were 18 pathologically benign SFTP cases (85.7%) and 3 malignant SFTP cases (14.3%).
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / surgery. Thoracic Surgery, Video-Assisted

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  • (PMID = 20009773.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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76. Kotoulas C, Fotinou M, Tsaroucha E, Konstantinou M, Lioulias A: Images in cardiothoracic surgery. Localized fibrous mesothelioma: an extremely rare benign pleural tumor. Ann Thorac Surg; 2006 Jun;81(6):2316
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Images in cardiothoracic surgery. Localized fibrous mesothelioma: an extremely rare benign pleural tumor.
  • [MeSH-major] Mesothelioma / radiography. Pleural Neoplasms / radiography. Tomography, X-Ray Computed

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  • (PMID = 16731187.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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77. Perna V, Rivas F, Morera R, Saumench J, Ramos R, Macia I, Ureña A, Escobar I, Villalonga R, Moya J: Localized (solitary) fibrous tumors of the pleura: an analysis of 15 patients. Int J Surg; 2008 Aug;6(4):298-301
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  • [Title] Localized (solitary) fibrous tumors of the pleura: an analysis of 15 patients.
  • BACKGROUND: Localized fibrous tumors of the pleura (LFTPs) are rare neoplasms, which are considered to originate from submesothelial connective tissue.
  • Malignant transformation was seen in 1 patient 26 months after resection of a benign tumor.
  • One of these underwent redo-surgery and required pneumonectomy; in the other one surgery is not indicated because at the time of diagnosis the patient was 85 years.
  • CONCLUSIONS: For histologically benign tumors, because of the risk of recurrence and malignant transformation, complete surgical resection is indicated and long-term follow-up is recommended in all patients.
  • [MeSH-major] Fibroma / mortality. Fibroma / pathology. Pleural Neoplasms / mortality. Pleural Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Pleura / pathology. Pleura / surgery. Prognosis. Radiography, Thoracic. Retrospective Studies. Risk Assessment. Survival Rate. Thoracotomy / methods. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18579460.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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78. Fatima S, Ahmed Z, Azam M: Benign metastasizing leiomyoma. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):802-4
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  • [Title] Benign metastasizing leiomyoma.
  • Benign metastasizing leiomyoma (BML) is a rare condition, affecting predominantly reproductive-age females with uterine leiomyomata and is most often associated with multiple benign-appearing smooth muscle tumors in lungs.
  • Postoperatively, she developed left-sided pleural effusion.
  • Histopathology of one of the pleura-based nodules revealed a neoplasm composed of interlacing fascicles of spindle cells with uniform nuclei.
  • The tumor cells were positive for alpha-smooth muscle actin and negative for CD34 immunohistochemical stain.
  • [MeSH-major] Leiomyoma / diagnosis. Lung Neoplasms / secondary. Pleural Neoplasms / secondary. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Actins / analysis. Adult. Antigens, CD34 / analysis. Female. Histocytochemistry. Humans. Hysterectomy. Immunohistochemistry. Microscopy. Pleural Effusion / diagnosis. Radiography, Thoracic. Tomography, X-Ray Computed

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  • (PMID = 21045423.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Antigens, CD34
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79. Krause E, Gürkov R, Klauss V: [Solitary fibrous tumor in the orbit. Case report and review of the literature]. HNO; 2009 Feb;57(2):169-72
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  • [Title] [Solitary fibrous tumor in the orbit. Case report and review of the literature].
  • [Transliterated title] Solitärer fibröser Tumor in der Orbita. Fallbericht und Literaturübersicht.
  • BACKGROUND: Solitary fibrous tumor (SFT) is a mesenchymal neoplasm with a benign growth behavior.
  • It was initially described in the pleura and has since been found in extrathoracic locations.
  • Tumor growth over 7 years led to a severe exophthalmos with loss of vision.
  • CONCLUSION: SFT is a rare differential diagnosis of orbital lesions and can be appropriately treated by surgical resection.

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  • [Cites] Eye (Lond). 2001 Feb;15(Pt 1):102-4 [11318269.001]
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  • (PMID = 19221826.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 18
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80. Takizawa I, Saito T, Kitamura Y, Arai K, Kawaguchi M, Takahashi K, Hara N: Primary solitary fibrous tumor (SFT) in the retroperitoneum. Urol Oncol; 2008 May-Jun;26(3):254-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary solitary fibrous tumor (SFT) in the retroperitoneum.
  • BACKGROUND: Solitary fibrous tumor (SFT) is an infrequent but distinct neoplasm, which generally arises from submesothelial connective tissue in the pleura.
  • The tumor size ranged between 2 and 26 (mean 9.1) cm.
  • The tumor cells were immunoreactive for vimentin in all cases, CD34 in 91% and Bcl-2 in 86%.
  • No significant difference was found between the recurrence rate of histologically benign and malignant cases.

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  • (PMID = 18452815.001).
  • [ISSN] 1078-1439
  • [Journal-full-title] Urologic oncology
  • [ISO-abbreviation] Urol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Proto-Oncogene Proteins c-bcl-2
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81. Filosso PL, Asioli S, Ruffini E, Rovea P, Macri' L, Sapino A, Bretti S, Lyberis P, Oliaro A: Radical resection of a giant, invasive and symptomatic malignant Solitary Fibrous Tumour (SFT) of the pleura. Lung Cancer; 2009 Apr;64(1):117-20
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  • [Title] Radical resection of a giant, invasive and symptomatic malignant Solitary Fibrous Tumour (SFT) of the pleura.
  • Solitary Fibrous Tumours (SFTs) of the pleura are rare neoplasms, with unpredictable biological behaviour.
  • Although usually benign, malignant SFTs are described, and they are often associated with large, necrotic and locally invasive tumours.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / pathology. Solitary Fibrous Tumor, Pleural / surgery

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  • (PMID = 19046791.001).
  • [ISSN] 0169-5002
  • [Journal-full-title] Lung cancer (Amsterdam, Netherlands)
  • [ISO-abbreviation] Lung Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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82. Regal MA, Al Rubaish AM, Al Ghoneimy YF, Hammad RI: Solitary benign fibrous tumors of the pleura. Asian Cardiovasc Thorac Ann; 2008 Apr;16(2):139-42
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  • [Title] Solitary benign fibrous tumors of the pleura.
  • Solitary benign fibrous tumors of the pleura are very rare.
  • Needle biopsy suggested the benign nature of the lesion.
  • Five tumors arose from visceral pleura, and 2 from parietal pleura.
  • The mean tumor diameter was 7.5 cm (range, 8-14 cm).
  • Histopathology and immunohistochemical staining confirmed the benign nature of the tumors.
  • All patients remained tumor-free during follow-up.
  • Wide local excision, including pulmonary and pleural resection, is recommended as the best therapeutic option.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / pathology

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  • (PMID = 18381873.001).
  • [ISSN] 1816-5370
  • [Journal-full-title] Asian cardiovascular & thoracic annals
  • [ISO-abbreviation] Asian Cardiovasc Thorac Ann
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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83. Deniz K, Kontas O, Tucer B, Kurtsoy A: Meningeal solitary fibrous tumor: report of a case and literature review. Folia Neuropathol; 2005;43(3):178-85
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  • [Title] Meningeal solitary fibrous tumor: report of a case and literature review.
  • Solitary fibrous tumor is a rare neoplasm that most often involves the pleura.
  • The increasing numbers of this neoplasm have also been reported to date in extrapleural sites.
  • Histologically, the tumor composed of spindle cell proliferation.
  • Tumor cells were found to be positive for CD34 and CD117 with immunohistochemical studies.
  • Seventy seven cases of meningeal solitary fibrous tumor from the literature are analysed and pathological, immunohistochemical and clinical features are discussed.
  • Solitary fibrous tumor has a slight female predominance, with a male to female ratio of 1:1.5.
  • A differential diagnosis is important because most of the solitary fibrous tumors usually behave in a benign fashion.

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  • (PMID = 16245214.001).
  • [ISSN] 1641-4640
  • [Journal-full-title] Folia neuropathologica
  • [ISO-abbreviation] Folia Neuropathol
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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84. Vo QT, Wolf JA, Turner JW, Murkis M, Saw D, Shemen LJ: Solitary fibrous tumor of the parapharyngeal space. Ear Nose Throat J; 2007 Aug;86(8):502-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the parapharyngeal space.
  • Solitary fibrous tumors are benign neoplasms of mesenchymal origin.
  • They usually arise from the visceral or parietal pleura and peritoneum, although they have been found in many areas throughout the body.
  • We report a case of solitary fibrous tumor of the parapharyngeal space.
  • Microscopically, the tumor contained spindle cells with areas of marked hypercellularity without a definitepattern.
  • Consistent with a benign lesion, there were few mitoses and no necrosis.
  • The tumor cells stained strongly positive for CD34 and vimentin.

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  • (PMID = 17915675.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Guo J, Chu X, Sun YE, Zhang L, Zhou N: Giant solitary fibrous tumor of the pleura: an analysis of five patients. World J Surg; 2010 Nov;34(11):2553-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Giant solitary fibrous tumor of the pleura: an analysis of five patients.
  • BACKGROUND: Solitary fibrous tumor of the pleura (SFTP) represents a clinical entity rarely encountered, especially in giant forms.
  • Complete surgical resection for giant tumor of pleura is a challenge.
  • All five patients underwent angiography and embolization of the tumor-supplying vessels within 24 h of surgery.
  • Tumors in three patients were pathologically benign; those in the other two were malignant.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / diagnosis. Solitary Fibrous Tumor, Pleural / surgery

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  • [Cites] Ann Thorac Surg. 2000 Dec;70(6):1808-12 [11156076.001]
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  • (PMID = 20628740.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2949573
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86. Shibata K, Yuki D, Sakata K: Multiple calcifying fibrous pseudotumors disseminated in the pleura. Ann Thorac Surg; 2008 Feb;85(2):e3-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple calcifying fibrous pseudotumors disseminated in the pleura.
  • Calcifying fibrous pseudotumor is an extremely rare benign lesion that develops in the pleura.
  • We describe a case of multiple lesions in the pleura.
  • The diagnosis was established by percutaneous needle biopsy.
  • The largest tumor was hanging down from the parietal pleura, and additional small nodules were disseminated throughout the pleural cavity.
  • [MeSH-major] Calcinosis / pathology. Pleural Diseases / pathology. Thoracic Surgery, Video-Assisted / methods
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Granuloma, Plasma Cell / pathology. Humans. Immunohistochemistry. Middle Aged. Neoplasm Staging. Risk Assessment. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 18222223.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 9
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87. Shimoyama T, Kimura B: [Peripheral intrapulmonary lipoma: report of a case]. Kyobu Geka; 2009 Dec;62(13):1186-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The differential diagnosis included benign lung tumors, such as intrapulmonary lymph nodes, granuloma etc.
  • To make diagnosis, a wedge resection of the pulmonary nodule was performed.
  • The tumor was diagnosed as a lipoma.
  • Although peripheral intrapulmonary lipoma is very rare, it should be kept in mind in the differential diagnosis of an intrapulmonary nodule.
  • [MeSH-minor] Female. Humans. Middle Aged. Pleura

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  • (PMID = 19999101.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Japan
  • [Number-of-references] 5
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88. Krishnadas R, Froeschle PO, Berrisford RG: Recurrence and malignant transformation in solitary fibrous tumour of the pleura. Thorac Cardiovasc Surg; 2006 Feb;54(1):65-7
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  • [Title] Recurrence and malignant transformation in solitary fibrous tumour of the pleura.
  • Solitary fibrous tumours of the pleura are mesenchymal neoplasms and recurrence with malignant progression after complete resection rarely occurs.
  • Even though the vast majority of these tumours are benign, complete resection as well as clinical and radiological follow-up are highly recommended because of the potentially adverse biological behaviour and the lack of radical treatment options other than surgery.
  • [MeSH-major] Neoplasm Recurrence, Local. Neoplasms, Fibrous Tissue / pathology. Pleural Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / blood. Bronchoscopy. Female. Humans. Immunohistochemistry. Neoplasm Staging. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 16485194.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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89. Meignan M, Paone G: [18-Fluoro-deoxy-glucose (15FDG) positon emission tomography (PET) for the evaluation of malignant pleural disease]. Rev Pneumol Clin; 2006 Apr;62(2):128-34
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [18-Fluoro-deoxy-glucose (15FDG) positon emission tomography (PET) for the evaluation of malignant pleural disease].
  • [Transliterated title] La tomographie par émission de positons (TEP) au 18-fluoro-déoxy-glucose (18FDG) dans l'évaluation de la pathologie pleurale maligne.
  • Use of 18FDG-PET for malignant tumors of the pleura raises certain technical difficulties because of the small size of the tumors and their diffuse distribution, but hybrid PET/CT machines offer a better localization of FDG uptake.
  • FDG-PET can discriminate between malignant and benign pleural tumors FDG uptake in the pleura is the best diagnostic criteria of malignancy.
  • The presence of FDG uptake in pleural effusion is less discriminate between benign and malignant disease.
  • For mesotheliomas, FDG-PET can difference malignant tumors from benign tumors of the pleura on the basis of the SUV value (<or > 2).
  • SUV<4 associated with an epithelial tumor is a sign of good prognosis at three years.
  • SUV > 4 associated with a non-epithelial tumor is a sign of poor prognosis.
  • [MeSH-major] Fluorodeoxyglucose F18. Pleural Neoplasms / diagnosis. Positron-Emission Tomography. Radiopharmaceuticals
  • [MeSH-minor] Humans. Mesothelioma / diagnosis

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  • (PMID = 16670667.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 19
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90. Pak PS, Yanagawa J, Abtin F, Wallace WD, Holmes EC, Lee JM: Surgical management of endobronchial solitary fibrous tumors. Ann Thorac Surg; 2010 Aug;90(2):659-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Solitary fibrous tumors of the pleura are rare neoplasms with both benign and malignant behaviors that are not reliably predicted by histologic findings.
  • The mass was tissue diagnosed to be a solitary fibrous tumor preoperatively, and was completely resected by sleeve resection of the left mainstem bronchus with lung preservation.
  • This report describes the challenging surgical management of an infrequently encountered tumor in a unique location.

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  • [Copyright] Copyright 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • [Cites] Ann Thorac Surg. 2002 Jul;74(1):285-93 [12118790.001]
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  • (PMID = 20667378.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / K23 CA131577-01A1; United States / NCI NIH HHS / CA / L30 CA142223-01; United States / NCI NIH HHS / CA / K23 CA131577; United States / NCI NIH HHS / CA / CA142223-01; United States / NCI NIH HHS / CA / K23 CA131577-02; United States / NCI NIH HHS / CA / CA131577-01A1; United States / NCI NIH HHS / CA / CA131577-02; United States / NCI NIH HHS / CA / L30 CA142223
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS311923; NLM/ PMC3158992
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91. Deniz H, Kibar Y, Güldür ME, Bakir K: Is D2-40 a useful marker for distinguishing malignant mesothelioma from pulmonary adenocarcinoma and benign mesothelial proliferations? Pathol Res Pract; 2009;205(11):749-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Is D2-40 a useful marker for distinguishing malignant mesothelioma from pulmonary adenocarcinoma and benign mesothelial proliferations?
  • Since pulmonary adenocarcinomas, malignant mesotheliomas (MM), and sometimes benign mesothelial proliferations show a great histomorphological resemblance to each other, an immunohistochemical panel is usually necessary for differential diagnosis.
  • The aim of this study is to compare D2-40 immunostaining in MM, pulmonary adenocarcinoma, and benign mesothelial proliferations.
  • In this retrospective study, D2-40 immunostaining was investigated in 37 cases of MM, 36 cases of pulmonary adenocarcinoma, and 31 cases of benign mesothelial proliferation.
  • The diagnosis of MM had previously been confirmed by a panel including calretinin, CK5/6, and CEA.
  • Predominantly membranous immunoreactivity was observed in 51% of MMs and in 55% of benign mesothelial proliferations.
  • We believe that D2-40 may be helpful in the differential diagnosis of MM from pleural involvement of pulmonary adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Antibodies, Monoclonal. Lung / metabolism. Lung Neoplasms / diagnosis. Mesothelioma / diagnosis. Solitary Fibrous Tumor, Pleural / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antibodies, Monoclonal, Murine-Derived. Biomarkers, Tumor / metabolism. Chi-Square Distribution. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Pleura / metabolism. Pleural Neoplasms / diagnosis. Pleural Neoplasms / metabolism

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  • (PMID = 19573998.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / monoclonal antibody D2-40
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92. Kelly RJ, Barrett C, Swan N, McDermott R: Metastatic phyllodes tumor causing small-bowel obstruction. Clin Breast Cancer; 2009 Aug;9(3):193-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Metastatic phyllodes tumor causing small-bowel obstruction.
  • Cystosarcoma phyllodes is an important but relatively uncommon fibroepithelial breast neoplasm that accounts for 0.5%-1.0% of female breast carcinomas.
  • These usually metastasize to the lung, pleura, bone, and liver.
  • This report highlights a unique case of a metastatic phyllodes breast tumor leading to small bowel obstruction.
  • Phyllodes tumors are generally classified into histologic subtypes of benign, intermediate, and malignant, using agreed classification systems.
  • The tumor characteristics that can lead to the dedifferentiation of a relatively benign phenotype to an overt malignant process are discussed.
  • [MeSH-major] Breast Neoplasms / pathology. Ileal Neoplasms / secondary. Intestinal Obstruction / etiology. Phyllodes Tumor / pathology
  • [MeSH-minor] Antibiotics, Antineoplastic / administration & dosage. Antineoplastic Agents, Alkylating / administration & dosage. Combined Modality Therapy. Doxorubicin / administration & dosage. Female. Humans. Ifosfamide / administration & dosage. Mastectomy. Middle Aged. Neoplasm Recurrence, Local

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  • Hazardous Substances Data Bank. DOXORUBICIN .
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  • (PMID = 19661046.001).
  • [ISSN] 1938-0666
  • [Journal-full-title] Clinical breast cancer
  • [ISO-abbreviation] Clin. Breast Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 0 / Antineoplastic Agents, Alkylating; 80168379AG / Doxorubicin; UM20QQM95Y / Ifosfamide
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93. Chermiti Ben Abdallah F, Bousnina S, Racil H, Ismail L, El Mezni F, Megdiche ML, Chabbou A: [Solitary malignant fibrous tumors of the pleura]. Rev Pneumol Clin; 2010 Jun;66(3):187-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Solitary malignant fibrous tumors of the pleura].
  • [Transliterated title] Les tumeurs fibreuses solitaires malignes de la plèvre.
  • Solitary fibrous tumours of the pleura are usually benign.
  • The roentgenograms and computed tomography scanning revealed a pleural tumour in both cases.
  • The immunohistochemical study confirmed the diagnosis of malignant solitary pleural fibroma.
  • Histopathology is very helpful in the diagnosis of malignant pleural fibroma.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural

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  • [Copyright] Copyright 2009. Published by Elsevier Masson SAS.
  • (PMID = 20561484.001).
  • [ISSN] 0761-8417
  • [Journal-full-title] Revue de pneumologie clinique
  • [ISO-abbreviation] Rev Pneumol Clin
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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94. Orki A, Kosar A, Akin O, Haciibrahimoglu G, Arman SB: Solitary fibrous tumor of the pleura. Thorac Cardiovasc Surg; 2008 Aug;56(5):287-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the pleura.
  • BACKGROUND: The aim of this study was to evaluate the clinical behavior of solitary fibrous tumors of the pleura and consider the optimal surgical approach for these rare tumors.
  • MATERIAL AND METHODS: We retrospectively reviewed the records of nine patients who underwent thoracotomy for tumor resection in our clinic between 1997 and 2006.
  • The tumor originated from the visceral pleura in 7 patients and was parietal in 2.
  • Pathological investigation reported the tumors to be a benign solitary fibrous tumor of the pleura in all 9 patients.
  • CONCLUSIONS: Solitary fibrous tumors of the pleura are rare neoplasms and can have giant diameters.
  • [MeSH-major] Solitary Fibrous Tumor, Pleural / surgery. Thoracotomy

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  • (PMID = 18615376.001).
  • [ISSN] 0171-6425
  • [Journal-full-title] The Thoracic and cardiovascular surgeon
  • [ISO-abbreviation] Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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95. Cichoz-Lach H, Kasztelan-Szczerbińska B, Słomka M: Gastrointestinal stromal tumors: epidemiology, clinical picture, diagnosis, prognosis and treatment. Pol Arch Med Wewn; 2008 Apr;118(4):216-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gastrointestinal stromal tumors: epidemiology, clinical picture, diagnosis, prognosis and treatment.
  • They may be benign or malignant (30%), and occur in every part of the gastrointestinal tract, however the stomach is the most common localization.
  • Symptoms are not typical and depend on the localization and the tumor size.
  • The metastases are rarely found in the lungs, pleura and bones.
  • The final diagnosis is mostly based on the pathologic findings of the removed tumor.
  • [MeSH-major] Biomarkers, Tumor / analysis. Gastrointestinal Neoplasms. Gastrointestinal Stromal Tumors. Proto-Oncogene Proteins c-kit / analysis

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  • (PMID = 18575421.001).
  • [Journal-full-title] Polskie Archiwum Medycyny Wewnetrznej
  • [ISO-abbreviation] Pol. Arch. Med. Wewn.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Number-of-references] 46
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96. Lee SC, Tzao C, Ou SM, Hsu HH, Yu CP, Cheng YL: Solitary fibrous tumors of the pleura: clinical, radiological, surgical and pathological evaluation. Eur J Surg Oncol; 2005 Feb;31(1):84-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumors of the pleura: clinical, radiological, surgical and pathological evaluation.
  • AIMS: To report a clinicopathological series of cases of solitary fibrous tumor of the pleura from Taiwan.
  • RESULTS: Eight patients, three men and five women aging from 34 to 71 years, underwent tumor resection and were followed in a period from 7 months to 13.5 years.
  • Six patients underwent standard thoracotomy and two had VATS for tumor excision.
  • Tumors were pathologically benign in seven patients and malignant in one.
  • Patients were all alive with no evidence of tumor recurrence at the time of this report.
  • [MeSH-major] Neoplasms, Fibrous Tissue / surgery. Pleural Neoplasms / surgery

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  • (PMID = 15642431.001).
  • [ISSN] 0748-7983
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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97. Znati K, Chbani L, El Fatemi H, Harmouch T, Kamaoui I, Tazi F, Bennis S, Amarti A: Solitary fibrous tumor of the kidney: a case report and review of the literature. Rev Urol; 2007;9(1):36-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the kidney: a case report and review of the literature.
  • A solitary fibrous tumor (SFT) is an unusual spindle cell neoplasm that usually occurs in the pleura but has recently been described in diverse extrapleural sites.
  • The tumor was well circumscribed and composed of a mixture of spindle cells and dense collagenous bands, with areas of necrosis or cystic changes noted macroscopically and microscopically.
  • Immunohistochemical studies revealed reactivity for CD34, CD99, and Bcl-2 protein, with no staining for keratin, S-100 protein, or muscle markers, confirming the diagnosis of SFT.
  • This tumor is benign in up to 90% of cases.
  • The immunohistochemical study is the key to diagnosis.

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  • (PMID = 17396171.001).
  • [ISSN] 1523-6161
  • [Journal-full-title] Reviews in urology
  • [ISO-abbreviation] Rev Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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98. de Castro MA Jr, Rosemberg NP, de Castro MA, de Castro AP, Wietzycoscki C, Mespaque C: Mediastinal teratoma mimicking pleural effusion on chest X-rays. J Bras Pneumol; 2007 Jan-Feb;33(1):113-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal teratoma mimicking pleural effusion on chest X-rays.
  • On a tomography scan of the chest, a collection of heterogeneous fluid, with irregular borders and 10.1 x 11.7 cm in size, was seen in the pleura of the lower two-thirds of the right hemithorax but was not encroaching on any of the adjacent structures.
  • Based on the hypothesis that these findings represented a benign mediastinal teratoma, an exploratory thoracotomy was performed, during which such a teratoma was found and completely excised.
  • The atypical presentation and considerable growth of the tumor hindered the pre-operative diagnosis.
  • [MeSH-major] Mediastinal Neoplasms / radiography. Pleural Effusion / radiography. Teratoma / radiography
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Radiography, Thoracic. Tomography, X-Ray Computed

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  • (PMID = 17568878.001).
  • [ISSN] 1806-3756
  • [Journal-full-title] Jornal brasileiro de pneumologia : publicaça̋o oficial da Sociedade Brasileira de Pneumologia e Tisilogia
  • [ISO-abbreviation] J Bras Pneumol
  • [Language] eng; por
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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99. Patel T, Bansal R, Trivedi P, Modi L, Shah MJ: Subcutaneous metastases of sarcomatoid mesothelioma with its differential diagnosis on fine needle aspiration--a case report. Indian J Pathol Microbiol; 2005 Oct;48(4):482-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Subcutaneous metastases of sarcomatoid mesothelioma with its differential diagnosis on fine needle aspiration--a case report.
  • Metastasis of mesothelioma of the pleura, to the skin and subcutis is an extremely rare occurrence.
  • A 25 year old woman, who had undergone chemotherapy, partial excision of tumor followed by radiotherapy of sarcomatoid mesothelioma of the pleura, presented three months later with painless widespread subcutaneous nodules.
  • It is essential to differentiate neoplasm metastatic to the skin and subcutis from primary and benign lesions of the same region.
  • FNAC is accurate and efficient, in conjugation with clinical history, and it also prevents surgical biopsy in the diagnosis of metastatic subcutaneous lesion.
  • [MeSH-major] Mesothelioma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Pleural Neoplasms. Skin Neoplasms / diagnosis. Skin Neoplasms / secondary. Subcutaneous Tissue

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  • (PMID = 16366102.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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100. Miyoshi K, Okumura N, Kokado Y, Matsuoka T, Kameyama K, Nakagawa T: Solitary fibrous tumor of the pleura with a minute malignant component and diaphragmatic vascular supply: report of a case. Surg Today; 2008;38(4):344-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the pleura with a minute malignant component and diaphragmatic vascular supply: report of a case.
  • We resected a fist-sized, solitary fibrous tumor of the pleura (SFTP) with a minute malignant component, following percutaneous embolization of its feeding artery.
  • The tumor had macroscopic characteristics of a benign SFTP, and most parts of it were microscopically benign.
  • We report this case to show that large and mostly benign SFTPs may contain malignant components, which can be overlooked.
  • [MeSH-major] Diaphragm / blood supply. Embolization, Therapeutic / methods. Pneumonectomy / methods. Solitary Fibrous Tumor, Pleural / blood supply. Thoracic Arteries
  • [MeSH-minor] Aged. Angiography. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Pulmonary Veins. Radiography, Thoracic. Thoracotomy / methods. Tomography, X-Ray Computed

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  • (PMID = 18368325.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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