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1. Paramés F, Freitas I, Martins JD, Trigo C, Pinto MF: Cardiac tumors: the 17-year experience of pediatric cardiology department. Rev Port Cardiol; 2009 Sep;28(9):929-40
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  • INTRODUCTION: Primary cardiac tumork may be benign or malignant and may arise anywhere in the endocardium, myocardium or pericardium.
  • They are rare in pediatric age-groups, with a prevalence in autopsy findings of 0.0017 to 0.28%; most are benign, malignant tumors accounting for only 10% of the total.
  • The diagnosis of primary cardiac tumor was based on echocardiography and/or magnetic resonance imaging.
  • The most frequent cardiac tumor was rhabdomyoma (67%), usually associated with tuberous sclerosis, followed by fibroma (17%) and fibroelastoma (8%) Although biopsy is the diagnostic gold standard, it was only performed in two patients.
  • Surgical removal of the tumor was performed in a single patient (with fibroelastoma) due to the perceived risk of pulmonary embolization.
  • DISCUSSION AND CONCLUSIONS: In our population, the most frequent tumor was rhabdomyoma associated with tuberous sclerosis.

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  • (PMID = 19998805.001).
  • [ISSN] 0870-2551
  • [Journal-full-title] Revista portuguesa de cardiologia : orgão oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology
  • [ISO-abbreviation] Rev Port Cardiol
  • [Language] eng; por
  • [Publication-type] Journal Article
  • [Publication-country] Portugal
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2. Karatolios K, Alter P, Maisch B: [Differentiation of malignant from nonmalignant, inflammatory pericardial effusions with biomarkers]. Herz; 2009 Dec;34(8):624-33
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  • [Title] [Differentiation of malignant from nonmalignant, inflammatory pericardial effusions with biomarkers].
  • Disorders of the pericardium are commonly associated with pericardial effusion.
  • Pericardiocentesis, pericardioscopy and targeted epicardial biopsy with consecutive pericardial fluid and epicardial biopsy analysis by cytology, molecular biology and immunology establish the underlying etiology in the majority of cases.
  • Of particular therapeutic and prognostic importance is the definite differentiation of malignant pericardial effusion from benign pericardial effusion.
  • With respect to pericardial disorders, a comprehensive approach combining clinical information, imaging biomarkers, biomarkers of pericardial effusion and analysis of epicardial biopsies often leads to the definite etiologic diagnosis of pericardial effusion.
  • Biomarkers of pericardial effusion include biochemical markers, autoantibodies, tumor markers, and cytokines.
  • Analysis of pericardial fluid specific gravity, protein level and lactate dehydrogenase (LDH) separates transudates from exsudates.
  • High adenosine deaminase levels (ADA) and low levels of carcinoembryonic antigen (CEA) in the pericardial effusion are observed in tuberculous pericarditis allowing the differentiation from malignant pericardial effusion.
  • Tumor markers in pericardial fluid have been used to diagnose malignant pericarditis.
  • CEA levels are significantly higher in malignant than benign effusion.
  • By a cutoff level of CEA > 5 ng/ml the diagnostic sensitivity and specificity are 75% and 100%, respectively, in the diagnosis of malignant pericardial effusion.
  • Further analysis of cytokines and mediators, serologic, immunologic and inflammatory markers may help to understand the pathophysiology of the pericardial disease and provide useful diagnostic information.
  • [MeSH-major] Biomarkers / blood. Heart Neoplasms / diagnosis. Myocarditis / blood. Myocarditis / diagnosis. Pericardial Effusion / blood. Pericardial Effusion / diagnosis

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  • (PMID = 20024642.001).
  • [ISSN] 1615-6692
  • [Journal-full-title] Herz
  • [ISO-abbreviation] Herz
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers
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3. Chryssagis K, Liangos A, Westhof F, Batz G, Diegeler A: Transesophageal echocardiography for detection of a papillary fibroelastoma of the aortic valve. Hellenic J Cardiol; 2010 Mar-Apr;51(2):170-4
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  • Papillary fibroelastoma (PF) is a benign cardiac tumor, typically attached to the cardiac valves.
  • After complete surgical removal of the tumor, we reconstructed the left coronary cusp with autologous pericardium.

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  • (PMID = 20378521.001).
  • [ISSN] 2241-5955
  • [Journal-full-title] Hellenic journal of cardiology : HJC = Hellēnikē kardiologikē epitheōrēsē
  • [ISO-abbreviation] Hellenic J Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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4. Cortesão N, Figueiredo A, Barata F, de Matos AC, Janelas C: [Pericardioperitoneal shunt in the treatment of pericardial effusions in neoplasic patients]. Rev Port Pneumol; 2007 Jan-Feb;13(1):71-81
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  • [Title] [Pericardioperitoneal shunt in the treatment of pericardial effusions in neoplasic patients].
  • [Transliterated title] Derivação pericardioperitoneal no tratamento de derrames pericárdicos em doentes neoplásicos.
  • Neoplasia-related pericardial effusions are a frequent finding and pose diagnostic and therapeutic challenges.
  • Although they appear in the context of an underlying neoplastic disease, 50% of these effusions have a benign etiology; they are indirectly caused by the tumor.
  • The remaining cases (neoplastic pericardial effusions - NPE) derive from extension of tu- moral disease to the epi and/or pericardium and have, therefore, a worst prognosis.
  • Pericardioperitoneal shunt (PPS) is a surgical pericardial drainage method, which has demonstrated its usefulness in the management of NPE.
  • [MeSH-major] Heart Neoplasms / complications. Pericardial Effusion / etiology. Pericardial Effusion / surgery. Pericardium / surgery. Peritoneum / surgery

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  • (PMID = 17315091.001).
  • [ISSN] 0873-2159
  • [Journal-full-title] Revista portuguesa de pneumologia
  • [ISO-abbreviation] Rev Port Pneumol
  • [Language] por
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Portugal
  • [Number-of-references] 18
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5. Joaquim MR, Braile DM, Arruda MV, Soares MJ: Right atrial lipoma resection and partial reconstruction using bovine pericardium. Rev Bras Cir Cardiovasc; 2009 Apr-Jun;24(2):239-41
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  • [Title] Right atrial lipoma resection and partial reconstruction using bovine pericardium.
  • Lipoma consists of a benign tumour corresponding to about 8% of all primary heart tumors.
  • When present, the symptoms are related to the size and location of such tumor.
  • We report a case of a 27-year-old man with a lipoma in the right atrium who underwent surgical treatment with tumor resection and partial reconstruction of the right atrium using bovine pericardium.
  • [MeSH-major] Heart Neoplasms / surgery. Lipoma / surgery. Pericardium / transplantation

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  • (PMID = 19768305.001).
  • [Journal-full-title] Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular
  • [ISO-abbreviation] Rev Bras Cir Cardiovasc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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6. Kraemer N, Balzer JC, Schoth F, Neizel M, Kuehl H, Günther RW, Krombach G: [Atrial tumors in cardiac MRI]. Rofo; 2009 Nov;181(11):1038-49
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  • About 75 % of them are benign.
  • The most common cardiac tumor is the myxoma.
  • Lymphogenic metastases favor the pericardium, while hematogenic spread prefers the myocardium.
  • [MeSH-minor] Diagnosis, Differential. Electrocardiography. Fibroma / diagnosis. Germany. Heart Valves / pathology. Heart Ventricles / pathology. Hemangioma / diagnosis. Hemangiosarcoma / diagnosis. Humans. Lipoma / diagnosis. Lymphoma / diagnosis. Myxoma / diagnosis. Pericardium / pathology. Practice Guidelines as Topic. Rhabdomyoma / diagnosis. Rhabdomyosarcoma / diagnosis. Sarcoma / diagnosis. Thrombosis / diagnosis

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  • (PMID = 19830642.001).
  • [ISSN] 1438-9010
  • [Journal-full-title] RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
  • [ISO-abbreviation] Rofo
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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7. Karpuz V, Ikitimur B, Karpuz H: [A survey of heart tumors: clinical and echocardiographic approach]. Anadolu Kardiyol Derg; 2007 Dec;7(4):427-35
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  • Heart tumors can be primary in origin, can develop from direct extension of a neighboring tumor or they can be the manifestation of metastasis of a distant tumor.
  • Myxomas are the most frequently encountered primary benign cardiac tumors.
  • Heart tumors may involve myocardium, endocardium, epicardium, pericardium, or any combination of the aforementioned layers.
  • On the other hand, the usual site for metastasis to the heart is the pericardium.
  • Surgery is the principal therapeutic option in benign tumors and when recurrences are not taken into account, they have favorable prognoses.

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  • (PMID = 18065342.001).
  • [ISSN] 1308-0032
  • [Journal-full-title] Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology
  • [ISO-abbreviation] Anadolu Kardiyol Derg
  • [Language] tur
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 49
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8. Cusimano RJ: Surgical management of cardiac tumors. Semin Diagn Pathol; 2008 Feb;25(1):76-81
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  • Although most are benign and have good long-term prognosis, surgery for malignant tumors, whether primary or secondary, usually carries poor long-term survival.
  • Bovine pericardium, Dacron grafts, and prosthetic valves are used for reconstruction.
  • Although cardiac transplantation has been used for tumors, long-term survival for anything but benign tumors is limited, making transplant a poor solution for any malignant tumors.
  • Outcome of resection of heart or great vessel tissue for tumors arising elsewhere is related more to the primary tumor than it is to the cardiac resection and reconstruction.

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  • (PMID = 18350926.001).
  • [ISSN] 0740-2570
  • [Journal-full-title] Seminars in diagnostic pathology
  • [ISO-abbreviation] Semin Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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9. Luna A, Ribes R, Caro P, Vida J, Erasmus JJ: Evaluation of cardiac tumors with magnetic resonance imaging. Eur Radiol; 2005 Jul;15(7):1446-55
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  • Primary cardiac neoplasms are rare, and are more commonly benign than malignant.
  • MRI allows evaluation of myocardial infiltration, pericardial involvement and/or extracardiac extension.
  • Suggestive features of malignancy are right side location, extracardiac extension, inhomogeneity in signal intensity of the tumor and pericardial effusion.
  • The use of intravenous contrast material improves tumor characterization and depiction of tumor borders.
  • MRI also allows differentiation of tumor from other nontumoral masses such as intracavitary tumors or fibromuscular elements of the posterior wall of the right atrium.
  • [MeSH-minor] Contrast Media. Humans. Image Enhancement / methods. Myocardium / pathology. Neoplasm Invasiveness. Pericardium / pathology

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  • (PMID = 15627179.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 33
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10. Rodríguez-Ortega MF, Jacobo-Valdivieso EJ, Flores-Calderón O, Del Sol García-Ortegón M, León-Hernández G, Luna-Saucedo MD: [Papillary cardiac fibroelastoma. An unusual presentation]. Cir Cir; 2007 Jul-Aug;75(4):293-6
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  • BACKGROUND: Papillary fibroelastoma is a rare benign tumor characterized morphologically since first being described in 1976.
  • Nevertheless, this tumor can be presented with a variety of clinical manifestations, making diagnosis challenging for the physician.
  • Echocardiogram reported degree I diastolic dysfunction, apical ventricular aneurysm, and unusual apical tumor of the septum and left ventricle.
  • Surgical procedure of choice is total tumor resection along with valve repair or replacement, if necessary, and in some cases cardiac endothelium resection and repair, with or without pericardium patch replacement.

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  • (PMID = 18053362.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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11. Meuris B, Gewillig M, Meyns B: Extreme levels of alpha-fetoprotein in a newborn with a benign intrapericardial teratoma. Cardiol Young; 2006 Feb;16(1):76-7
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  • [Title] Extreme levels of alpha-fetoprotein in a newborn with a benign intrapericardial teratoma.
  • We report a neonate presenting with an intrapericardial benign teratoma and an exceptionally high level of alpha-fetoprotein.
  • The tumour in our patient, however, proved to be completely benign.
  • [MeSH-major] Biomarkers, Tumor / blood. Heart Neoplasms / blood. Pericardium. Teratoma / blood. alpha-Fetoproteins / metabolism

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  • (PMID = 16454881.001).
  • [ISSN] 1047-9511
  • [Journal-full-title] Cardiology in the young
  • [ISO-abbreviation] Cardiol Young
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / alpha-Fetoproteins
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12. Comoglio C, Sansone F, Delsedime L, Campanella A, Ceresa F, Rinaldi M: Mesothelial cyst of the pericardium, absent on earlier computed tomography. Tex Heart Inst J; 2010;37(3):354-7
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  • [Title] Mesothelial cyst of the pericardium, absent on earlier computed tomography.
  • Pericardial cysts are benign intrathoracic lesions that are considered to be congenital.
  • Computed tomography revealed a pericardial cyst on the right side of the anterior mediastinum, near the confluence of the brachiocephalic vein and the superior vena cava and very close to the ascending aorta.
  • Due to the cyst's unusual location and the ineffectiveness of medical therapy, we excised the tumor via median sternotomy.
  • We found a large (7 x 4-cm), well-circumscribed, unilocular cyst, which unexpectedly involved the outside pericardial surface and the phrenic nerve.
  • Histopathologic examination confirmed that the lesion was a simple mesothelial cyst of the pericardium.
  • We know of no other report of a pericardial cyst that had gone undetected upon earlier computed tomography.
  • We believe that surgical treatment of pericardial cysts should be reserved for patients who have severe symptoms due to complications, or when diagnosis is uncertain and malignancy is suspected.

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  • (PMID = 20548822.001).
  • [ISSN] 1526-6702
  • [Journal-full-title] Texas Heart Institute journal
  • [ISO-abbreviation] Tex Heart Inst J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2879185
  • [Keywords] NOTNLM ; Dyspnea/etiology / mediastinal cyst/complications/diagnosis/pathology/radiography/surgery/ultrasonography / pericardial effusion/etiology / tomography, X-ray computed / treatment outcome
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13. Kolettis TN, Tsourelis LP, Stavridis GT, Alivizatos PA: Right atrial and septal reconstruction after tumor excision: the single-patch technique. Interact Cardiovasc Thorac Surg; 2009 May;8(5):561-2
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  • [Title] Right atrial and septal reconstruction after tumor excision: the single-patch technique.
  • Surgical excision is the only therapy for benign atrial tumors, if serious complications are to be avoided.
  • We propose a simplified technique whereupon a single autologous pericardial patch is used to not only close the septal defect, but to also reconstruct the right atrium.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / surgery. Pericardium / transplantation

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  • (PMID = 19240059.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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14. Ramasubbu K, Wheeler TM, Reardon MJ, Dokainish H: Visceral pericardial hemangioma: unusual location for a rare cardiac tumor. J Am Soc Echocardiogr; 2005 Sep;18(9):981
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Visceral pericardial hemangioma: unusual location for a rare cardiac tumor.
  • Magnetic resonance imaging confirmed the presence of the tumor, without extension into adjacent cardiac chambers or pericardial effusion.
  • At operation, a 4.6- x 3.0-cm tumor attached to the visceral pericardium was excised.
  • Hemangiomas account for 2% to 5% of benign cardiac tumors, arising from the cardiac ventricles, atria, valves, and, rarely, the epicardium/pericardium.
  • This case illustrates a very rare location for an unusual benign cardiac tumor.
  • [MeSH-major] Heart Neoplasms / surgery. Heart Neoplasms / ultrasonography. Hemangioma / surgery. Hemangioma / ultrasonography. Pericardium / surgery. Pericardium / ultrasonography

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  • (PMID = 16153530.001).
  • [ISSN] 1097-6795
  • [Journal-full-title] Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
  • [ISO-abbreviation] J Am Soc Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Takeda M, Kasai T, Enomoto Y, Takano M, Morita K, Kadota E, Nonomura A: 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis. Pathol Int; 2010 May;60(5):395-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens.
  • The purpose of this study is to evaluate the diagnostic utility of 9p21 homozygous deletion assessed by FISH in mesothelial neoplasm and hyperplasia of Japanese patients using paraffin-embedded tissue.
  • In contrast, no cases of adenomatoid tumor, benign mesothelial multicystic tumor, reactive mesothelial hyperplasia or pleuritis showed 9p21 deletion (P < 0.005).
  • 9p21 homozygous deletion correlated well with p16 protein expression in the tumor cells.
  • [MeSH-minor] Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. DNA, Neoplasm / analysis. Epithelium / pathology. Female. Gene Deletion. Gene Dosage. Humans. Pericardium / metabolism. Pericardium / pathology

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  • (PMID = 20518890.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
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16. Georghiou GP, Shapira Y, Stamler A, Birk E, Berman M, Vidne BA, Sahar G: Surgical excision of papillary fibroelastoma for known or potential embolization. J Heart Valve Dis; 2005 Nov;14(6):843-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND AND AIM OF THE STUDY: Papillary fibroelastoma (PFE) is a rare and histologically benign tumor, but it may have malignant propensity for life-threatening complications.
  • Indications for surgery were myocardial infarction (both aortic tumors), previous stroke (mitral tumor), and preventive (tricuspid tumor).
  • For the first aortic tumor, the aortic valve was reconstructed with a patch of autologous pericardium.

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  • (PMID = 16359067.001).
  • [ISSN] 0966-8519
  • [Journal-full-title] The Journal of heart valve disease
  • [ISO-abbreviation] J. Heart Valve Dis.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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17. Liddle AD, Anderson DR, Mishra PK: Intrapericardial teratoma presenting in fetal life: intrauterine diagnosis and neonatal management. Congenit Heart Dis; 2008 Nov-Dec;3(6):449-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intrapericardial teratoma is a rare and often fatal germ-cell tumor of neonates.
  • It is usually histologically benign but may cause death in utero by hydrops fetalis or by pericardial tamponade in the early days of life.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Neoplasms / ultrasonography. Pericardium / ultrasonography. Teratoma / ultrasonography. Ultrasonography, Prenatal

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  • (PMID = 19037988.001).
  • [ISSN] 1747-0803
  • [Journal-full-title] Congenital heart disease
  • [ISO-abbreviation] Congenit Heart Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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18. Dorobantu M, Fruntelata A, Constantinescu D, Racoveanu I, Ardeleanu C, Tatu-Chitoiu G, Lazar IC: Primary left heart malignant fibrous histiocytoma. Eur J Echocardiogr; 2005 Jun;6(3):225-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We present the case of a 53 years-old woman presenting with congestive heart failure and pleural and pericardial effusions, in whom transthoracic and transesophageal echocardiography revealed multilocular cardiac tumor involving the left atrium wall, extending into the pericardium.
  • Tumor was excised surgically and proved to be a malignant fibrous histiocytoma, primarily confined to the heart.
  • The pericardial involvement has been only rarely reported.
  • [MeSH-major] Echocardiography. Heart Neoplasms / ultrasonography. Histiocytoma, Benign Fibrous / ultrasonography

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  • (PMID = 15894243.001).
  • [ISSN] 1525-2167
  • [Journal-full-title] European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology
  • [ISO-abbreviation] Eur J Echocardiogr
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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19. Kisselbach C, Ristic AD, Pankuweit S, Karatolius K, Maisch B: [Women and pericardial neoplastic manifestations of the heart and pericardium]. Herz; 2005 Aug;30(5):409-15; quiz 429-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Women and pericardial neoplastic manifestations of the heart and pericardium].
  • Data on epidemiology and incidence are rare: there is only an estimated incidence of cardiac neoplasm at necropsy ranging from 0,001% to 0,3%.
  • The majority of the primary tumors are benign.
  • The most common tumor entity is benign cardiac myxoma.
  • Indeed in women breast cancer is the most common metastatic tumor associated with pericardial effusion.
  • To prevent death from tamponade, pericardiocentesis, in addition to the systemic chemotherapy, is mandatory, best when instillation of chemotherapeutics (cisplatin or thiotepa) or radioisotopes is given into the pericardial sac to prevent recurrence of the effusion.
  • METHODS: A retrospective study was conducted of all patients with cardiac and pericardial neoplasm exactly diagnosed by endomyocardial or epicardial biopsy and pericardiocentesis, using hospital medical records and a biopsy and pericardiocentesis registry from 2000-2005 with 297 patients.
  • Pericardial effusion and biopsy analyses included biochemistry, cytology, serology, microbiology, histology, immunohistology, and polymerase chain reaction (PCR).
  • RESULTS: In 76 cases (25.6%) a neoplasm was the reason for a pericardial effusion.
  • 36 women suffered from the breast carcinoma (47%) and 40 males lung cancer (42%) as the firstly metastatic tumor.
  • There was no recurrence of a relevant pericardial effusion in patients who were treated by intrapericardial instillation of cisplatin (30 mg/m2 body surface in 100 ml 0.9% NaCl).
  • By contrast, the preventive checkup and aftercare will gain more prognostic importance, especially in case of breast cancer, to earlier recognize a secondary cardiac neoplasm by biopsy and pericardiocentesis with intrapericardial treatment of neoplastic pericarditis.

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  • (PMID = 16132244.001).
  • [ISSN] 0340-9937
  • [Journal-full-title] Herz
  • [ISO-abbreviation] Herz
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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20. Alsaileek A, Tepe SM, Alveraz L, Miller DV, Tajik J, Breen J: Diagnostic features of cardiac hemangioma on cardiovascular magnetic resonance, a case report. Int J Cardiovasc Imaging; 2006 Oct;22(5):699-702
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cardiac hemangiomas are benign cardiac tumors that account for 5-10% of all benign tumors of the heart (Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR.
  • They occur in any cardiac location, including the pericardium (Brodwater B, Erasmus J, McAdams HP, Dodd L.
  • Magnetic resonance imaging (MRI) has an excellent contrast resolution and multiplanar capability to allow optimal evaluation of myocardial infiltration, pericardial involvement and/or extracardiac extension (Brown JI, Barakos JA, Higgins CB.
  • It illustrates the capability of the MRI to non-invasively detect histological and flow characteristics of the tumor.
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Female. Gadolinium. Heart Septum / pathology. Heart Ventricles / pathology. Humans. Middle Aged. Neoplasm Invasiveness. Ultrasonography

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  • (PMID = 16705478.001).
  • [ISSN] 1569-5794
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; AU0V1LM3JT / Gadolinium
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21. Suehiro K, Pritzwald-Stegmann P, Lee KM, Teoh HH, Alison PM: Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor. Ann Thorac Surg; 2006 Jun;81(6):2289-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mediastinal and pulmonary metastases of malignant ossifying fibromyxoid tumor.
  • Ossifying fibromyxoid tumor is usually a benign tumor.
  • However some of these tumors with histologic and clinical evidence of malignancy have also been reported and little information is available regarding surgery for metastatic ossifying fibromyxoid tumor.
  • We present a case involving extensive excision of a huge metastatic ossifying fibromyxoid tumor occupying the upper mediastinum and upper half of the right hemithorax.
  • [MeSH-minor] Adult. Brain Neoplasms / complications. Brain Neoplasms / secondary. Diagnostic Errors. Fatal Outcome. Female. Head and Neck Neoplasms / pathology. Head and Neck Neoplasms / surgery. Humans. Lipoma / diagnosis. Neoplasm Invasiveness. Pericardium / pathology. Pericardium / surgery. Phrenic Nerve / pathology. Phrenic Nerve / surgery. Pneumonectomy. Radiotherapy, Adjuvant. Reoperation. Seizures / etiology. Skin Neoplasms / pathology. Skin Neoplasms / surgery. Superior Vena Cava Syndrome / etiology

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  • (PMID = 16731174.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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22. Novitzky D, Guglin M, Sheffield C: Cardiac autotransplantation for removal of left atrial hemangioma and a review of the literature. Heart Surg Forum; 2009 Oct;12(5):E279-84
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A mobile left atrial tumor measuring 6 x 4 x 5 cm was found attached to the left atrial dome, left atrial cuff, and left pulmonary veins.
  • The tumor could not be adequately excised, and reconstruction of the defect was not feasible with the heart in situ.
  • We therefore decided to explant the heart and excise the tumor with a 0.5-cm margin of healthy tissue.
  • The broad left atrial defect was reconstructed with bovine pericardium.
  • The heart was reimplanted back into the pericardial cavity.
  • The pathology diagnosis was a benign cavernous hemangioma.
  • To our knowledge, this report is the first of cardiac autotransplantation for benign hemangioma.

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  • (PMID = 19833595.001).
  • [ISSN] 1522-6662
  • [Journal-full-title] The heart surgery forum
  • [ISO-abbreviation] Heart Surg Forum
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 38
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23. Ramírez GA, Spattini G, Altimira J, García B, Vilafranca M: Clinical and histopathological features of a thymolipoma in a dog. J Vet Diagn Invest; 2008 May;20(3):360-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • This study presents a case of a canine thymolipoma, which is a rare, slow-growing, benign tumor of the thymus composed of mature adipose tissue and thymic tissue.
  • The mass was attached to, and silhouetted, the adjacent pericardium.
  • To the authors' knowledge, this is the first description of this uncommon neoplasm in a dog.
  • The possible histogenesis for this neoplasia in a dog is also discussed.

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  • (PMID = 18460628.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Baghai-Wadji M, Sianati M, Nikpour H, Koochekpour S: Pleomorphic adenoma of the trachea in an 8-year-old boy: a case report. J Pediatr Surg; 2006 Aug;41(8):e23-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The patient was subjected to right carinal resection, pneumonectomy, and pericardial patch tracheoplasty for reconstruction of the trachea.
  • Histopathological examination and immunohistochemical staining of tumor specimens were compatible with pleomorphic adenoma.
  • Postoperative follow-up of this patient for a period of 6 months showed satisfactory results with no complications or tumor recurrence.
  • We present not only a very rare benign tracheal tumor in children but also demonstrate successful usage of a free pericardial patch for tracheal reconstruction, although direct anastomosis failed to provide an adequate anastomotic lumen.
  • [MeSH-minor] Child. Humans. Male. Pericardium / transplantation. Respiratory Insufficiency / etiology

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  • (PMID = 16863832.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Ucak A, Inan K, Onan B, Yilmaz AT: Resection of intrapericardial hibernoma associated with constrictive pericarditis. Interact Cardiovasc Thorac Surg; 2009 Oct;9(4):717-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Hibernoma is a benign soft-tissue tumor, which arises from the remnants of fetal brown adipose tissue.
  • Out of less than 300 cases of hibernoma described to date, pericardial sac is an unusual localization to develop.
  • When the tumor increases in size, this benign pathology can lead to compression of cardiac chambers and cause life-threatening complications in an asymptomatic patient.
  • Here, the authors present the case of a 20-year-old male who underwent an operation for the treatment of constrictive pericarditis, in which an intrapericardial sessile lesion over diaphragmatic surface of pericardial sac was incidentally discovered.
  • The tumor was excised and diagnosed as hibernoma.
  • [MeSH-major] Cardiac Surgical Procedures. Heart Diseases / surgery. Lipoma / surgery. Pericarditis, Constrictive / surgery. Pericardium / surgery

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  • (PMID = 19596706.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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26. Gonzalez M, Krueger T, Schaefer SC, Ris HB, Perentes JY: Asymptomatic intrapericardial mature teratoma. Ann Thorac Surg; 2010 Jun;89(6):e46-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Benign mature teratomas are the most common type of germ cell tumors that arise in the anterior mediastinum.
  • Intrapericardial teratomas are a rare manifestation of this tumor type, which are generally diagnosed during infancy because of the heart compression symptoms they produce.
  • [MeSH-major] Heart Neoplasms / diagnosis. Pericardium. Teratoma / diagnosis

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20494011.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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