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1. Tiufekchieva E: [Seven-year-experience in the hysteroresection of submucous myomas]. Akush Ginekol (Sofiia); 2007;46(4):23-8
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  • [Title] [Seven-year-experience in the hysteroresection of submucous myomas].
  • AIM OF THE RESEARCH: to summarize the results of hysteroscopic resections of submucous myomas, performed in the last 7 years in our clinic and to compare the results with those cited in the literature.
  • RESULTS: 142 submucous myomas were resected.
  • The mean diameter was 32.15 mm (from 5 to 55 mm); 8 myomas were 50 mm and more in diameter.
  • After 3 years 7 women, out of 31 observed, had abnormal bleeding; 5 women underwent hysterectomies because of intramural myomas, atypical endometrial hyperplasia, endometrial cancer, uterine prolapse.
  • CONCLUSION: The results of the study confirmed the advantages and the excellent potentialities of the hysteroscopy in the treatment of the submucous myomas.
  • For this reason hysteroscopy should be the method of choice for treatment of the submucous myomas.

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  • (PMID = 17974191.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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2. Shi HM, Wang PZ, Wang SY, Yu Q: [Imaging features and differentiated diagnosis of desmoplastic fibroma of the jaw bones]. Shanghai Kou Qiang Yi Xue; 2007 Oct;16(5):489-92
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  • RESULTS: On conventional radiographs, the lesion was presented as a purely lytic tumor that did not contain any mineralized matrix.
  • The zone of transition between tumor and normal bone was typically narrow and well defined but not sclerotic.
  • On CT scan, increased bone marrow density (n=3), a homogeneous soft-tissue density mass displaced adjacent muscle with lingual cortex eroded (n=3) were noted.
  • CONCLUSIONS: Recognition of DF is important because DF is more aggressive than other benign fibrous lesions, necessitating a wide surgical and careful long-term follow-up for local recurrence.

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  • (PMID = 18004478.001).
  • [ISSN] 1006-7248
  • [Journal-full-title] Shanghai kou qiang yi xue = Shanghai journal of stomatology
  • [ISO-abbreviation] Shanghai Kou Qiang Yi Xue
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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3. Fayad LM, Wang X, Salibi N, Barker PB, Jacobs MA, Machado AJ, Weber KL, Bluemke DA: A feasibility study of quantitative molecular characterization of musculoskeletal lesions by proton MR spectroscopy at 3 T. AJR Am J Roentgenol; 2010 Jul;195(1):W69-75
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  • SUBJECTS AND METHODS: Thirty-three subjects with 34 musculoskeletal lesions (four histologically proven malignant, 13 histologically proven benign or proven benign by follow-up analysis, and 17 posttreatment fibrosis with documented stability for 6-36 months) underwent single-voxel 3-T MRS studies.
  • The choline concentrations of benign and malignant lesions were compared using the Mann-Whitney test.
  • For five benign lesions (two neurofibromas, two schwannomas, and one enchondroma), the choline concentrations were 0.11, 0.28, 0.13, 0.8, and 1.2 mmol/kg, respectively.
  • For seven benign lesions (two hematomas, two bone cysts, one lipoma, one giant cell tumor, and one pigmented villonodular synovitis), the spectra showed negligible choline content.
  • Average choline concentrations were different for malignant and benign lesions (2.7 vs 0.5 mmol/kg; p = 0.01).

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  • (PMID = 20566784.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 1R01CA100184; United States / NCI NIH HHS / CA / CA100184-01A2; United States / Intramural NIH HHS / / ZIA CL090019-01; United States / NCI NIH HHS / CA / CA100184-03; United States / NCI NIH HHS / CA / CA100184-02; United States / NCI NIH HHS / CA / P50CA103175; United States / Intramural NIH HHS / / ZIA EB000072-01; United States / NCI NIH HHS / CA / R01 CA100184-02; United States / NCI NIH HHS / CA / P50 CA103175; United States / NCI NIH HHS / CA / R01 CA100184-03; United States / NCI NIH HHS / CA / R01 CA100184-01A2; United States / NCI NIH HHS / CA / R01 CA100184
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Contrast Media; 0 / Protons; N91BDP6H0X / Choline
  • [Other-IDs] NLM/ NIHMS245710; NLM/ PMC3035623
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4. Taveira-DaSilva AM, Pacheco-Rodriguez G, Moss J: The natural history of lymphangioleiomyomatosis: markers of severity, rate of progression and prognosis. Lymphat Res Biol; 2010 Mar;8(1):9-19
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  • Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, characterized by proliferation of abnormal smooth muscle-like cells (LAM cells) that can metastasize, leading to the formation of lung cysts, fluid-filled cystic structures in the axial lymphatics (e.g., lymphangioleiomyomas), and angiomyolipomas, benign tumors usually involving the kidneys, comprising LAM cells and adipocytes, intermixed with incompletely developed vascular structures.
  • LAM occurs sporadically or in association with tuberous sclerosis complex, an autosomal dominant syndrome characterized by hamartoma-like tumor growths.
  • Methods used to grade the severity of disease are the LAM histology score, semiquantitative and quantitative computer tomography, pulmonary function testing, and cardiopulmonary exercise testing.
  • Currently, progression of disease is best assessed by serial measurements of FEV(1), DL(CO), and exercise performance.
  • Several potential biomarkers, such as LAM cells in peripheral blood, urine, and chyle and chemokines, vascular endothelial growth factors, and matrix metalloproteinases, may be useful as diagnostic tools or markers of organ involvement, disease severity, and progression.

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  • (PMID = 20235883.001).
  • [ISSN] 1557-8585
  • [Journal-full-title] Lymphatic research and biology
  • [ISO-abbreviation] Lymphat Res Biol
  • [Language] ENG
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2883494
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5. Fatima S, Ahmed Z, Azam M: Benign metastasizing leiomyoma. Indian J Pathol Microbiol; 2010 Oct-Dec;53(4):802-4
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  • [Title] Benign metastasizing leiomyoma.
  • Benign metastasizing leiomyoma (BML) is a rare condition, affecting predominantly reproductive-age females with uterine leiomyomata and is most often associated with multiple benign-appearing smooth muscle tumors in lungs.
  • Histopathology of one of the pleura-based nodules revealed a neoplasm composed of interlacing fascicles of spindle cells with uniform nuclei.
  • The tumor cells were positive for alpha-smooth muscle actin and negative for CD34 immunohistochemical stain.

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  • (PMID = 21045423.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / ACTA2 protein, human; 0 / Actins; 0 / Antigens, CD34
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6. Tzanakis NE, Giannopoulos GA, Efstathiou SP, Rallis GE, Nikiteas NI: Angiomyofibroblastoma of the spermatic cord: a case report. J Med Case Rep; 2010;4:79
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  • INTRODUCTION: Angiomyofibroblastoma is a benign soft tissue tumor with tendency to arise in the vulva.
  • At operation, a 4.5 cm well-circumscribed solid tumor was found adherent to the spermatic cord.
  • The tumor consisted of spindle-shaped cells proliferating in short fascicles between numerous medium-sized blood vessels with thin and hyalinized walls.
  • Immunostaining showed positivity for vimentin, CD34, desmin and smooth muscle actin.
  • CONCLUSION: This unusual neoplasm should be distinguished from aggressive angiomyxoma and other myxoid malignant tumors with widespread metastatic potential.

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  • (PMID = 20202207.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
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7. Lokeshwar VB, Cerwinka WH, Lokeshwar BL: HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion. Cancer Res; 2005 Mar 15;65(6):2243-50
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  • [Title] HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion.
  • Hyaluronic acid promotes tumor progression; however, the functions of hyaluronidase in cancer are largely unknown.
  • Whereas HYAL1-S and vector tumors infiltrated skeletal muscle and blood vessels, HYAL1-AS tumors resembled benign neoplasia.
  • HYAL1-S and vector tumors expressed significantly higher amounts of HYAL1 (in tumor cells) and hyaluronic acid (in tumor-associated stroma) than HYAL1-AS tumors.
  • These results show that HYAL1 expression in bladder cancer cells regulates tumor growth and progression and therefore serves as a marker for high-grade bladder cancer.
  • [MeSH-minor] Apoptosis / physiology. Cell Cycle / physiology. Cell Growth Processes / physiology. Cell Line, Tumor. Extracellular Matrix / metabolism. Humans. Hyaluronic Acid / metabolism. Neoplasm Invasiveness. Neoplasm Transplantation. Neovascularization, Pathologic / enzymology. Neovascularization, Pathologic / pathology. Transfection. Transplantation, Heterologous

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  • (PMID = 15781637.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA 072821-06A2
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 9004-61-9 / Hyaluronic Acid; EC 3.2.1.35 / Hyaluronoglucosaminidase
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8. Zhu L, Lang JH, Liu CY, Shi HH, Sun ZJ, Fan R: Clinical assessment for three routes of hysterectomy. Chin Med J (Engl); 2009 Feb 20;122(4):377-80
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  • METHODS: One hundred and one women undergoing hysterectomy for myoma had the procedure performed by laparoscopic assisted vaginal hysterectomy (LAVH), total vaginal hysterectomy (TVH) or total abdominal hysterectomy (TAH) in a randomized study.
  • Vaginal hysterectomy is the most cost-effective approach but the final choice for the route of hysterectomy can depend on many factors such as gynecological disease, patients' health status and experiences of the gynecologist.
  • [MeSH-major] Hysterectomy / methods. Hysterectomy / standards. Myoma / surgery

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  • (PMID = 19302739.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] China
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9. Jeremic K, Gojnic M, Milenkovic V, Boskovic V, Berisavac M, Zecević N: Placental site trophoblastic tumor: a case report. Eur J Gynaecol Oncol; 2006;27(1):98-100
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  • [Title] Placental site trophoblastic tumor: a case report.
  • Patient K.N., age 30, nulliparous deliveries and with one miscarriage, was admitted to the Institute of Gynecology and Obstetrics, Clinical Center of Serbia, in December 2000 with the following diagnosis: Uterine myoma and adnexal mass.
  • [MeSH-major] Chorionic Gonadotropin / blood. Trophoblastic Tumor, Placental Site / pathology. Trophoblastic Tumor, Placental Site / surgery. Uterine Neoplasms / pathology. Uterine Neoplasms / surgery
  • [MeSH-minor] Adult. Biopsy, Needle. Female. Follow-Up Studies. Humans. Hysterectomy / methods. Immunohistochemistry. Magnetic Resonance Imaging. Magnetic Resonance Spectroscopy. Neoplasm Staging. Pregnancy. Risk Assessment. Treatment Outcome

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  • (PMID = 16550983.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Chorionic Gonadotropin
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10. Markowska A, Belloni AS, Rucinski M, Parenti AR, Nardelli GB, Drews K, Nussdorfer GG, Malendowicz LK: Leptin and leptin receptor expression in the myometrium and uterine myomas: Is leptin involved in tumor development? Int J Oncol; 2005 Dec;27(6):1505-9
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  • [Title] Leptin and leptin receptor expression in the myometrium and uterine myomas: Is leptin involved in tumor development?
  • Evidence has been provided that leptin, in addition to being involved in obesity development, plays a role in the regulation of the female reproductive system, angiogenesis and tumor growth.
  • Uterine myoma is a rather common disease that develops more frequently in obese than lean women, where plasma leptin concentrations are elevated.
  • RT-PCR and Western blotting showed that leptin was expressed, as mRNA and protein, in several uterine myomas but not in normal myometrium, while leptin receptors were expressed in both tissues.
  • Immunocytochemistry indicated that leptin-immunoreactivity was located in both myometrial cells and blood-vessel walls of uterine myomas.
  • Leptin(22-56), at concentrations of 10(-7) and 10(-6) M, enhanced the proliferative activity of both the normal myometrium and myoma cells in primary culture.
  • Taken together, our findings allow us to suggest that leptin, acting through autocrine-paracrine mechanism(s), may be involved in the development of uterine myomas.
  • [MeSH-major] Leptin / genetics. Myoma / genetics. Myometrium / metabolism. Receptors, Cell Surface / genetics. Uterine Neoplasms / genetics
  • [MeSH-minor] Blotting, Western. Cell Proliferation / drug effects. Dose-Response Relationship, Drug. Female. Gene Expression. Humans. Immunohistochemistry. RNA, Messenger / genetics. RNA, Messenger / metabolism. Receptors, Leptin. Reverse Transcriptase Polymerase Chain Reaction. Tumor Cells, Cultured

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  • (PMID = 16273205.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Leptin; 0 / RNA, Messenger; 0 / Receptors, Cell Surface; 0 / Receptors, Leptin; 0 / leptin receptor, human
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11. Hakverdi S, Dolapçioğlu K, Güngören A, Yaldiz M, Hakverdi AU: Multiple uterine angioleiomyomas mimicking an ovarian neoplasm: a case report. Eur J Gynaecol Oncol; 2009;30(5):592-4
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  • [Title] Multiple uterine angioleiomyomas mimicking an ovarian neoplasm: a case report.
  • Angioleiomyoma is a rare benign neoplasm that originates from smooth muscle cells and contains thick-walled blood vessels.
  • On pathologic examination of the specimen, the tumor was diagnosed as an angioleiomyoma.
  • Here, we present a case of giant-multiple uterine angioleiomyomas mimicking an ovarian neoplasm.
  • [MeSH-major] Angiomyoma / diagnosis. Angiomyoma / pathology. Ovarian Neoplasms / diagnosis. Uterine Diseases / diagnosis. Uterine Diseases / pathology

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  • (PMID = 19899426.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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12. Arrabal-Polo MA, Arrabal-Martin M: Resolution of right ureteral lesion after subtotal hysterectomy due to benign pathology. A clinical case study. Int Urogynecol J; 2010 Nov;21(11):1435-7
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  • [Title] Resolution of right ureteral lesion after subtotal hysterectomy due to benign pathology. A clinical case study.
  • INTRODUCTION: Ureteral lesion during gynecological surgery to correct benign uterine pathology is around 0.03-2.0%, and usually occurs at the ligature of blood vessels.
  • DISCUSSION: We describe here the case story of a 40-year-old female patient, who, after subtotal hysterectomy for myomas, presented with acute abdominal pain, and was diagnosed with a right ureteral lesion, via CAT imaging; the patient received direct ureterovesical implantation of double J catheter, which was kept in place for 8 weeks.

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  • [Cites] Obstet Gynecol. 2009 Jan;113(1):6-10 [19104353.001]
  • [Cites] Clin Obstet Gynecol. 1998 Sep;41(3):755-63 [9742371.001]
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  • (PMID = 20571768.001).
  • [ISSN] 1433-3023
  • [Journal-full-title] International urogynecology journal
  • [ISO-abbreviation] Int Urogynecol J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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13. Kang JL, Wang DY, Wang XX, Yu J: Up-regulation of apoptosis by gonadotrophin-releasing hormone agonist in cultures of endometrial cells from women with symptomatic myomas. Hum Reprod; 2010 Sep;25(9):2270-5
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  • [Title] Up-regulation of apoptosis by gonadotrophin-releasing hormone agonist in cultures of endometrial cells from women with symptomatic myomas.
  • BACKGROUND: The aim of the present study was to evaluate the effect of gonadotrophin-releasing hormone agonist (GnRH-a), which is widely used in the medical treatment of symptomatic myomas, on the rate of endometrial cell apoptosis in cultures from women with symptomatic myomas.
  • METHODS: The study included 36 women with symptomatic myomas without endometrial hyperplasia or endometrial carcinoma, and 22 controls.
  • RESULTS: Levels of spontaneous apoptosis were significantly lower in endometrial cultures from patients with symptomatic myomas than in those from control subjects (P < 0.01).
  • Concentrations as low as 10(-7) M GnRH-a enhanced apoptosis in endometrial cultures from patients with symptomatic myomas (3.48% +/- 0.27% apoptotic cells in untreated samples and 25.45 +/- 0.95% in cells treated with 10(-7) M GnRH-a; P <0.01).
  • CONCLUSIONS: GnRH-a stimulates apoptosis in endometrial cells from patients with symptomatic myomas and this could, at least in part, account for the therapeutic action of GnRH-a.
  • [MeSH-minor] Adult. Annexin A5 / metabolism. Biopsy. Female. Flow Cytometry. Humans. In Situ Nick-End Labeling. Middle Aged. Osmolar Concentration. Time Factors. Triptorelin Pamoate / pharmacology. Tumor Cells, Cultured. Uterine Hemorrhage / prevention & control

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  • (PMID = 20634188.001).
  • [ISSN] 1460-2350
  • [Journal-full-title] Human reproduction (Oxford, England)
  • [ISO-abbreviation] Hum. Reprod.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Annexin A5; 0 / Antineoplastic Agents, Hormonal; 33515-09-2 / Gonadotropin-Releasing Hormone; 57773-63-4 / Triptorelin Pamoate
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14. Zaitseva M, Vollenhoven BJ, Rogers PA: Retinoic acid pathway genes show significantly altered expression in uterine fibroids when compared with normal myometrium. Mol Hum Reprod; 2007 Aug;13(8):577-85
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  • Fibroids are benign neoplasms of myometrial smooth muscle cells (SMC).
  • Despite being the most common tumor in humans, their etiology is poorly understood.

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  • (PMID = 17553814.001).
  • [ISSN] 1360-9947
  • [Journal-full-title] Molecular human reproduction
  • [ISO-abbreviation] Mol. Hum. Reprod.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Isoenzymes; 0 / RBP1 protein, human; 0 / RBP2 protein, human; 0 / Retinol-Binding Proteins; 0 / Retinol-Binding Proteins, Cellular; 5688UTC01R / Tretinoin; EC 1.1.1.1 / Alcohol Dehydrogenase; EC 1.2.1.- / aldehyde dehydrogenase 1; EC 1.2.1.3 / Aldehyde Dehydrogenase; EC 1.2.1.36 / Retinal Dehydrogenase; EC 2.1.1.43 / Histone-Lysine N-Methyltransferase
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15. Bhattacharya B, Dilworth HP, Iacobuzio-Donahue C, Ricci F, Weber K, Furlong MA, Fisher C, Montgomery E: Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions. Am J Surg Pathol; 2005 May;29(5):653-9
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  • [Title] Nuclear beta-catenin expression distinguishes deep fibromatosis from other benign and malignant fibroblastic and myofibroblastic lesions.
  • They must be distinguished from a host of fibroblastic and myofibroblastic lesions as well as from smooth muscle neoplasms.
  • Formalin-fixed, paraffin-embedded sections from 21 lesions from 20 patients with deep fibromatoses were stained with monoclonal beta-catenin antibody (Transduction Laboratories) and compared with low-grade fibromyxoid sarcoma (n=12), leiomyosarcoma (n=10), various other fibrosarcoma variants (n=13, including 3 myofibrosarcomas, 3 sclerosing epithelioid fibrosarcomas, 5 low-grade fibrosarcomas, 1 classic fibrosarcoma arising in dermatofibrosarcoma protuberans, 1 inflammatory myxohyaline tumor/myxoinflammatory fibroblastic sarcoma), myofibroma/myofibromatosis (n=12), nodular fasciitis (n=11), and scars (n=9).
  • All other lesions tested (n=67) lacked nuclear labeling for beta-catenin, showing only cytoplasmic accumulation. beta-Catenin immunohistochemistry separates deep fibromatosis from entities in the differential diagnosis, a finding that can be exploited for diagnosis.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Cicatrix / metabolism. Cicatrix / pathology. Cytoplasm / metabolism. Cytoplasm / pathology. Diagnosis, Differential. Fasciitis / metabolism. Fasciitis / pathology. Female. Humans. Male. Middle Aged. beta Catenin

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  • (PMID = 15832090.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CTNNB1 protein, human; 0 / Cytoskeletal Proteins; 0 / Trans-Activators; 0 / beta Catenin
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16. Levy AD, Arnáiz J, Shaw JC, Sobin LH: From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. Radiographics; 2008 Mar-Apr;28(2):583-607; quiz 621-2
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  • Primary malignant mesothelioma, multicystic mesothelioma, primary peritoneal serous carcinoma, leiomyomatosis peritonealis disseminata, and desmoplastic small round cell tumor are the most prominent of these rare lesions.
  • Multicystic mesothelioma occurs most frequently in women and has benign or indolent biologic behavior in the majority of patients.
  • Leiomyomatosis peritonealis disseminata is a rare, benign proliferative process that also occurs exclusively in women and is characterized by multiple smooth muscle nodules throughout the peritoneum.
  • Desmoplastic small round cell tumor is a highly aggressive malignancy of unknown origin that occurs most often in the peritoneal cavity of young men.
  • Knowledge of the spectrum of imaging findings in this group of primary peritoneal tumors, along with their clinical and pathologic characteristics, is important in the evaluation of patients with diffuse peritoneal disease.

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  • (PMID = 18349460.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 55
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17. Meng GZ, Zhang HY, Bu H, Zhang XL, Pang ZG, Ke Q, Liu X, Yang G: Myofibroblastic sarcomas: a clinicopathological study of 20 cases. Chin Med J (Engl); 2007 Mar 5;120(5):363-9
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  • BACKGROUND: Myofibroblastic sarcoma was used to be a controversial neoplasm.
  • Immunohistochemically, the tumor cells expressed smooth muscle actin (18/20), muscle specific actin (16/20), fibronectin (20/20) and desmin (2/20).
  • Ultrastructurally, the tumor cells revealed abundant rough endoplasmic reticulum and longitudinally arranged fine filaments with focal densities in the cytoplasm.
  • Nine cases recurred locally 17 to 46 months after the initial excision, and 9 cases were alive with no evidence of disease.
  • CONCLUSIONS: Myofibroblastic sarcomas, which exhibit diverse histological appearance, can easily be misdiagnosed as benign tumors.

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  • (PMID = 17376304.001).
  • [ISSN] 0366-6999
  • [Journal-full-title] Chinese medical journal
  • [ISO-abbreviation] Chin. Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Desmin
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18. Yang J, Frassica FJ, Fayad L, Clark DP, Weber KL: Analysis of nondiagnostic results after image-guided needle biopsies of musculoskeletal lesions. Clin Orthop Relat Res; 2010 Nov;468(11):3103-11
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  • METHODS: We retrospectively reviewed data from a prospectively collected database for a case-control study of 508 image-guided needle biopsies of patients with suspected musculoskeletal tumors between 2003 and 2008.
  • Malignant tumors had a higher IC rate than benign tumors (5% vs. 0%); fibromyxoid sarcoma and rare subtypes of osteosarcoma had higher IC rates than other diagnoses.
  • We believe these biopsies appropriate in selected circumstances but a key factor for appropriate use is an experienced musculoskeletal tumor team with frequent communication to correlate clinical, radiographic, and histologic information for each patient.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Bone Neoplasms / pathology. Muscle Neoplasms / pathology. Radiography, Interventional. Tomography, X-Ray Computed. Ultrasonography, Interventional

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  • (PMID = 20383617.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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19. Mangioni S, Viganò P, Lattuada D, Abbiati A, Vignali M, Di Blasio AM: Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor. J Clin Endocrinol Metab; 2005 Sep;90(9):5349-55
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  • [Title] Overexpression of the Wnt5b gene in leiomyoma cells: implications for a role of the Wnt signaling pathway in the uterine benign tumor.
  • The molecular causes of the disease remain unknown.
  • OBJECTIVE: Using an oligonucleotide microarray-based hybridization analysis, we observed that a Wnt family member transcript, Wnt5b, was overexpressed in smooth muscle cells (SMC) derived from leiomyomas when compared with matched myometrial cells.
  • Based on this finding and on previous observations, we have hypothesized that altered expression of specific Wnt family members might be involved in leiomyoma formation and/or growth.

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  • (PMID = 15972578.001).
  • [ISSN] 0021-972X
  • [Journal-full-title] The Journal of clinical endocrinology and metabolism
  • [ISO-abbreviation] J. Clin. Endocrinol. Metab.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cell Cycle Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / Proto-Oncogene Proteins; 0 / RNA, Messenger; 0 / SFRP1 protein, human; 0 / WNT5B protein, human; 0 / Wnt Proteins
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20. Hsu WC, Hwang JS, Chang WC, Huang SC, Sheu BC, Torng PL: Prediction of operation time for laparoscopic myomectomy by ultrasound measurements. Surg Endosc; 2007 Sep;21(9):1600-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The myoma weights were calculated and converted into mass units (g) by an assumed smooth muscle density of 1.04 g/cm3.
  • Myomas were weighed immediately after operation, and the correlation between these two weights was assessed by linear regression and limits of agreement.
  • RESULTS: Of 109 patients, 203 myomas were removed laparoscopically with a mean ultrasound-measured myoma weight of 137.9 (100.7) g, a diameter of the dominant myoma of 6.30 (1.92) cm, and an operation time of 125 (41) min.
  • Strong correlations were observed between the ultrasound-measured and operated myoma weights.
  • A predictive model, in which operation time = 0.14 x ultrasound-measured myoma weight + 1.68 x BMI + 5.21 x operated myoma number + 0.06 x (ultrasound-measured myoma weight x operated myoma number) + 43.97, was developed.
  • CONCLUSIONS: Operation time was significantly related to the myoma weight measured by ultrasound.

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  • (PMID = 17294306.001).
  • [ISSN] 1432-2218
  • [Journal-full-title] Surgical endoscopy
  • [ISO-abbreviation] Surg Endosc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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21. Leite GK, Korkes HA, Viana Ade T, Pitorri A, Kenj G, Sass N: [Myomectomy in the second trimester of pregnancy: case report]. Rev Bras Ginecol Obstet; 2010 Apr;32(4):198-201
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  • [Transliterated title] Miomectomia em gestação de segundo trimestre: relato de caso.
  • Uterine leiomyomas are characterized as a benign disease and are observed in 2 to 3% of all normal pregnancies.
  • Ultrasonography revealed a myoma nodule measuring 9.1 x 7.7 cm; the patient was hospitalized and medicated, being also submitted to laparotomy and myomectomy due to worsening of her condition.

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  • (PMID = 20625689.001).
  • [ISSN] 1806-9339
  • [Journal-full-title] Revista brasileira de ginecologia e obstetrícia : revista da Federação Brasileira das Sociedades de Ginecologia e Obstetrícia
  • [ISO-abbreviation] Rev Bras Ginecol Obstet
  • [Language] por
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Brazil
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22. Erian J, El-Toukhy T, Chandakas S, Theodoridis T, Hill N: One hundred cases of laparoscopic subtotal hysterectomy using the PK and Lap Loop systems. J Minim Invasive Gynecol; 2005 Jul-Aug;12(4):365-9
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  • DESIGN: Prospective observational study (Canadian Task Force classification II-2).
  • Clinically, the uterus was enlarged in 70 patients, and preoperative ultrasound scanning suggested the presence of uterine myomas in 42 patients.

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  • (PMID = 16036200.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Chiu YC, Lin JW, Changchien CS, Huang CC, Liu SY, Yi LN, Chiu KW, Wu KL, Chen YY, Chou FF, Hu TH: Clinicopathological characteristics and prognosis of patients with small intestinal stromal tumors. J Formos Med Assoc; 2005 Dec;104(12):905-12
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  • METHODS: A total of 82 surgically resected and pathologically diagnosed smooth muscle tumors of small bowel in patients treated from January 1986 to December 2000 were included.
  • Immunohistochemical studies were performed on these tumors with antibodies of CD117, CD34, smooth muscle actin (SMA), desmin and S-100.
  • Survival analysis demonstrated that tumor size < 5 cm (p = 0.021), mitosis number < 5/50 high-power field (p < 0.001), SMA-positive (p = 0.027), non-epithelioid cell type (p = 0.005) and tumor with skeinoid fibers (p = 0.010) predicted longer disease-free survival after operation.
  • Multivariate analysis revealed that mitotic number (p = 0.001), cell morphology (p = 0.031) and tumor size (p = 0.004) were independent prognostic factors.
  • SMA reactivity is a predictor of benign clinical behavior in SISTs.
  • Tumor mitotic numbers, tumor size, and cell type were independent prognostic factors for patients with SISTs after operation.

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  • (PMID = 16607447.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Singapore
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24. Hsieh CH, Wei MC, Hsu YP, Chong NS, Chen YJ, Hsiao SM, Hsieh YP, Wang LY, Shueng PW: Should helical tomotherapy replace brachytherapy for cervical cancer? Case report. BMC Cancer; 2010;10:637
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  • Magnetic resonance imaging (MRI) showed a cervical tumor with direct invasion of the right parametrium, bilateral hydronephrosis, and multiple uterine myomas.
  • International Federation of Gynecology and Obstetrics (FIGO) stage IIIB cervical cancer was diagnosed.
  • Concurrent chemoradiation therapy (CCRT) followed by SBRT delivered via HT was administered instead of brachytherapy because of the presence of multiple uterine myomas with bleeding tendency.
  • Total abdominal hysterectomy was performed after 6 weeks of treatment because of the presence of multiple uterine myomas.
  • Neither pelvic MRI nor results of histopathologic examination at X-month follow-up showed evidence of tumor recurrence.
  • [MeSH-minor] Biopsy. Chemotherapy, Adjuvant. Dose Fractionation. Female. Humans. Hysterectomy. Magnetic Resonance Imaging. Middle Aged. Neoplasm Invasiveness. Treatment Outcome. Uterine Hemorrhage / etiology. Uterine Hemorrhage / therapy. Vaginal Smears

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  • (PMID = 21092235.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3001446
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25. Lasmar RB, Barrozo PR, Dias R, Oliveira MA: Submucous myomas: a new presurgical classification to evaluate the viability of hysteroscopic surgical treatment--preliminary report. J Minim Invasive Gynecol; 2005 Jul-Aug;12(4):308-11
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  • [Title] Submucous myomas: a new presurgical classification to evaluate the viability of hysteroscopic surgical treatment--preliminary report.
  • STUDY OBJECTIVE: To develop a new preoperative classification of submucous myomas for evaluating the viability and the degree of difficulty of hysteroscopic myomectomy.
  • DESIGN: Retrospective study (Canadian Task Force classification II-3) SETTING: University teaching hospitals.
  • PATIENTS: Fifty-five patients who underwent hysteroscopic resection of submucous myomas.
  • INTERVENTION: The possibility of total resection of the myoma, the operating time, the fluid deficit, and the frequency of any complications were considered.
  • The myomas were classified according to the Classification of the European Society for Gynaecological Endoscopy (ESGE) and by our group's new classification (NC), which considers not only the degree of penetration of the myoma into the myometrium, but also adds in such parameters as the distance of the base of the myoma from the uterine wall, the size of the nodule (cm), and the topography of the uterine cavity.
  • MEASUREMENTS AND MAIN RESULTS: In 57 myomas, hysteroscopic surgery was considered complete.
  • CONCLUSIONS: We believe that the NC gives more clues as to the difficulties of a hysteroscopic myomectomy than the standard ESGE classification.
  • It should be stressed that the number of hysteroscopic myomectomies used in this analysis was low, and it would be interesting to evaluate the performance of the classification in a larger number of patients.
  • [MeSH-major] Hysteroscopy. Leiomyoma / classification. Leiomyoma / surgery. Uterine Neoplasms / classification. Uterine Neoplasms / surgery

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  • (PMID = 16036188.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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26. Nasiadek M, Krawczyk T, Sapota A: Tissue levels of cadmium and trace elements in patients with myoma and uterine cancer. Hum Exp Toxicol; 2005 Dec;24(12):623-30
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  • [Title] Tissue levels of cadmium and trace elements in patients with myoma and uterine cancer.
  • The aim of this study was to investigate the cadmium (Cd), copper (Cu), zinc (Zn), iron (Fe), magnesium (Mg) and calcium (Ca) concentrations in uterine cancer and uterine myoma.
  • Tissue levels of six elements in 15 uterine cancers and 28 uterine myomas were measured by atomic absorption spectrometry.
  • The samples were collected from women aged 32-79 (uterine myomas, uterine cancer and non-lesion uterine tissues from the same women).
  • The results showed that the tissue Cd concentration was significantly lower in myoma than in non-lesion tissue.
  • In uterine myoma, a significant increase of Mg and Mg/Ca ratio, as well as a decrease in Fe concentration were found.
  • Statistical analysis showed no correlation between smoking habits, age, menopausal status and concentration of Cu, Zn, Fe, Mg and Ca trace metals in myoma or cancer tissue.

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  • (PMID = 16408615.001).
  • [ISSN] 0960-3271
  • [Journal-full-title] Human & experimental toxicology
  • [ISO-abbreviation] Hum Exp Toxicol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Trace Elements; 00BH33GNGH / Cadmium
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27. Touboul C, Fernandez H, Deffieux X, Berry R, Frydman R, Gervaise A: Uterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility. Fertil Steril; 2009 Nov;92(5):1690-3
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  • [Title] Uterine synechiae after bipolar hysteroscopic resection of submucosal myomas in patients with infertility.
  • INTERVENTION(S): Patients underwent bipolar hysteroscopic resection of myomas between 2001 and 2006, and an outpatient hysteroscopy was performed 2 months after the fibroid resection.
  • RESULT(S): The submucosal myomas were intracavitary class 0 (n = 12), intramural class 1 (n = 19), and intramural class 2 (n = 22).
  • The mean myoma size was 25 +/- 11 mm.
  • Myoma size >or=3.5 cm and age <35 years were associated with a significantly higher pregnancy rate in univariate and multivariate analysis.
  • [MeSH-major] Hysteroscopy / adverse effects. Infertility, Female / epidemiology. Myoma / surgery. Uterine Diseases / epidemiology. Uterine Neoplasms / surgery


28. Dilek S, Ertunc D, Tok EC, Cimen R, Doruk A: The effect of myomectomy on health-related quality of life of women with myoma uteri. J Obstet Gynaecol Res; 2010 Apr;36(2):364-9
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  • [Title] The effect of myomectomy on health-related quality of life of women with myoma uteri.
  • Many studies have evaluated the effect of other methods rather than myomectomy on HRQoL, and have focused solely on the presence of myoma without regarding any concurrent pelvic pathology.
  • METHODS: This study involved 80 patients with myomas and 75 controls.
  • Domains of the Short Form - 36 (SF-36) questionnaire were evaluated pre- and postoperatively in 72 women with myomas.
  • Furthermore, any correlations between myoma characteristics and SF-36 physical components (PC) and mental components (MC) were investigated.
  • RESULTS: All SF-36 domains were lower in women with myoma uteri than in the control group, except for physical and social function.
  • There was no correlation between PC and MC scores and the number, location and total volume of the myomas.
  • However, fundal and posteriorly positioned myomas were related with the PC score, and posterior myomas with the MC score.
  • CONCLUSION: The findings from this study suggest that myomectomy improves HRQoL, and that myoma characteristics may modulate quality of life domains.

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  • (PMID = 20492389.001).
  • [ISSN] 1447-0756
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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29. Lardinois D, Weder W, Roudas M, von Schulthess GK, Tutic M, Moch H, Stahel RA, Steinert HC: Etiology of solitary extrapulmonary positron emission tomography and computed tomography findings in patients with lung cancer. J Clin Oncol; 2005 Oct 1;23(28):6846-53
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  • Histopathologic examinations of these 32 lesions revealed a second clinically unsuspected malignancy or a recurrence of a previous diagnosed carcinoma in six patients (19%) and a benign tumor or inflammatory lesion in 26 patients (81%).
  • Benign tumors and inflammatory lesions included eight colon adenomas, four Warthin's tumors, one granuloma of the lower jaw, one adenoma of the thyroid gland, one compensatory muscle activity due to vocal chord palsy, two occurrences of arthritis, three occurrences of reflux esophagitis, two occurrences of pancreatitis, two occurrences of diverticulitis, one hemorrhoidal inflammation, and one rib fracture.
  • CONCLUSION: Solitary extrapulmonary FDG accumulations in patients with newly diagnosed lung cancer should be analyzed critically for correct staging and optimal therapy, given that up to half of the lesions may represent unrelated malignancies or benign disease.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / radionuclide imaging. Lung Neoplasms / radionuclide imaging. Neoplasm Metastasis / radionuclide imaging. Positron-Emission Tomography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Female. Fluorodeoxyglucose F18. Humans. Inflammation. Male. Middle Aged. Neoplasm Staging. Prospective Studies. Radiopharmaceuticals. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 16192576.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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30. Ozturk E, Ugur MG, Balat O, Kutlar I, Dikensoy E, Cebesoy B: An analysis of hysteroscopy experience over a seven-year period. Clin Exp Obstet Gynecol; 2010;37(2):150-1
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  • The most common pathologies for referal to operative hysteroscopy were uterine septum, endometrial polyps, Asherman's syndrome, submucous myomas, and other uterine anomalies.
  • [MeSH-major] Hysteroscopy. Uterine Diseases / diagnosis

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  • (PMID = 21077511.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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31. Kook PH, Wiederkehr D, Makara M, Reusch CE: [Megaesophagus secondary to an esophageal leiomyoma and concurrent esophagitis]. Schweiz Arch Tierheilkd; 2009 Oct;151(10):497-501
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  • The only clinical abnormality was halitosis, a neurological examination was normal.
  • No other disorder causing abnormal esophageal motor function could be identified.
  • Microscopically a leio-myoma with mild multifocal mixed-cell esophagitis was diagnosed.
  • This report illustrates how a potentially curable disease such as leiomyoma can clinically mimic acquired idiopathic megaesophagus and emphasizes that additional diagnostic procedures (contrast study, esophagoscopy) can be indicated in individual cases.
  • [MeSH-major] Dog Diseases / diagnosis. Esophageal Achalasia / veterinary. Esophageal Neoplasms / veterinary. Esophagitis / veterinary. Leiomyoma / veterinary

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  • (PMID = 19780011.001).
  • [ISSN] 0036-7281
  • [Journal-full-title] Schweizer Archiv für Tierheilkunde
  • [ISO-abbreviation] Schweiz. Arch. Tierheilkd.
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Switzerland
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32. Chen HW, Tzeng CR: Applications of microarray in reproductive medicine. Chang Gung Med J; 2006 Jan-Feb;29(1):15-24
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  • Recent studies of microarray-related techniques used to study oocyte fertilization, early embryo development, implantation and some infertility-related diseases (endometriosis and myoma) are discussed and summarized in this review.

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  • (PMID = 16642725.001).
  • [ISSN] 2072-0939
  • [Journal-full-title] Chang Gung medical journal
  • [ISO-abbreviation] Chang Gung Med J
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China (Republic : 1949- )
  • [Number-of-references] 64
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33. Krysiak R, Okopień B, Herman ZS: [Gonadotropin-releasing hormone analogs]. Pol Merkur Lekarski; 2005 May;18(107):585-9
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  • Moreover, we review the potential role of these agents in pharmacotherapy of endometriosis, uterine myomas and central precocious puberty.

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  • (PMID = 16161962.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 33515-09-2 / Gonadotropin-Releasing Hormone
  • [Number-of-references] 38
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34. Makris N, Vomvolaki E, Mantzaris G, Kalmantis K, Hatzipappas J, Antsaklis A: Role of a bipolar resectoscope in subfertile women with submucous myomas and menstrual disorders. J Obstet Gynaecol Res; 2007 Dec;33(6):849-54
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  • [Title] Role of a bipolar resectoscope in subfertile women with submucous myomas and menstrual disorders.
  • METHODS: From January 2000 to December 2005, we studied 59 women of reproductive age with menorrhagia, submucous myomas and one or more infertility factors.
  • Fifteen of the 59 women displayed submucous myoma type O (intracavitary), 34 displayed submucous myoma type I (less than 50% within the myometrium) and the remaining 10 women displayed myoma type II (over 50% being within the myometrium).
  • The mean age and standard deviation of these patients was 34.6 +/- 4.4 years and the average size of myomas was 15 +/- 10 mm.
  • Treatment of these myomas was by hysteroscopic resection using a bipolar resectoscope.
  • The pregnancy rate was notably higher when the sole reason of subfertility was the presence of myoma (54.16%), and when the size of the myoma was equal to 2.5 cm (75%) or more.
  • CONCLUSION: The use of the bipolar resectoscope in hysteroscopic removal of small submucous myomas is shown to be both feasible and effective in controlling menorrhagia and increasing the pregnancy rate in subfertile women, when submucous myomas are the only reason of infertility.

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  • (PMID = 18001453.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Japan
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35. Takeuchi H, Kitade M, Kikuchi I, Shimanuki H, Kumakiri J, Kinoshita K: Adhesion-prevention effects of fibrin sealants after laparoscopic myomectomy as determined by second-look laparoscopy: a prospective, randomized, controlled study. J Reprod Med; 2005 Aug;50(8):571-7
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  • A total of 91 patients showing a minimal myoma > 5 cm, excluding pedunculated myomas, underwent LM alone: 32 patients in the control group, 29 in the fibrin gel group and 30 patients in the fibrin sheet group.
  • Although no significant differences were found in the incidence of de novo adnexal adhesions, the lowest rate was found in the fibrin gel group, with 4/32 patients (12.5%) in the control group, 2/29 patients (6.8%) in the fibrin gel group and 5/30 patients (16.7%) in the fibrin sheet group.
  • CONCLUSION: After LM for myomas as large as > or = 5 cm, postoperative adhesions were observed in > or = 50% of patients.
  • [MeSH-major] Fibrin Tissue Adhesive / therapeutic use. Leiomyoma / surgery. Postoperative Complications / prevention & control. Tissue Adhesives / therapeutic use. Uterine Diseases / prevention & control. Uterine Neoplasms / surgery

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  • (PMID = 16220761.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fibrin Tissue Adhesive; 0 / Gels; 0 / Tissue Adhesives
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36. Kongnyuy EJ, van den Broek N, Wiysonge CS: A systematic review of randomized controlled trials to reduce hemorrhage during myomectomy for uterine fibroids. Int J Gynaecol Obstet; 2008 Jan;100(1):4-9
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  • There was no evidence of effect in blood loss with myoma enucleation by morcellation and oxytocin.

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  • (PMID = 17894936.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0E43V0BB57 / Misoprostol; 11000-17-2 / Vasopressins; 50-56-6 / Oxytocin; Y8335394RO / Bupivacaine
  • [Number-of-references] 25
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37. Horo GA, Touré-Ecra FA, Fanny M, N'Gbesso D, Koné M: [Diagnosis of endometrial pathologies in West Africa: contribution of saline infusion sonography. Experience of Yopougon's teaching hospital (Abidjan, Ivory Coast)]. Gynecol Obstet Fertil; 2006 Dec;34(12):1142-6
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  • [Transliterated title] Diagnostic des pathologies endométriales en Afrique subsaharienne: contribution de l'hystérosonographie. Expérience du CHU de Yopougon (Abidjan, Côte d'Ivoire).
  • The polyps (23,8%), and the mucous myomas (14%) dominate the endometrial pathologies.
  • [MeSH-major] Uterine Diseases / diagnosis. Uterine Diseases / ultrasonography. Uterus / ultrasonography

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  • (PMID = 17113809.001).
  • [ISSN] 1297-9589
  • [Journal-full-title] Gynécologie, obstétrique & fertilité
  • [ISO-abbreviation] Gynecol Obstet Fertil
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 451W47IQ8X / Sodium Chloride
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38. Kaymak O, Ustunyurt E, Okyay RE, Kalyoncu S, Mollamahmutoglu L: Myomectomy during cesarean section. Int J Gynaecol Obstet; 2005 May;89(2):90-3
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  • MATERIALS AND METHODS: Using a retrospective case-control design; 40 patients who underwent myomectomy at time of cesarean delivery were compared with the control group consisted of 80 patients with myomas who underwent cesarean delivery alone.


39. Blockeel C, De Beeck BO, Bourgain C, Amy JJ: Myomatous erythrocytosis syndrome. Natl Med J India; 2005 Sep-Oct;18(5):247-9
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  • Uterine myomas are common but erythrocytosis caused by these is rarely seen.
  • A voluminous, retroperitoneally located and focally degenerated myoma was associated with severe secondary erythrocytosis (haematocrit: 65.5%) which resolved after hysterectomy.
  • Local tissue hypoxia, which is more prone to develop in a pedunculated myoma, stimulates the process.
  • Other prerequisites are a very large size of the myoma and the absence of menometrorrhagia of a severity such as to cause a depletion in iron reserves.

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  • (PMID = 16433138.001).
  • [ISSN] 0970-258X
  • [Journal-full-title] The National medical journal of India
  • [ISO-abbreviation] Natl Med J India
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Receptors, Erythropoietin; 11096-26-7 / Erythropoietin
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40. Chiang ER, Chen TH: Multiple glomus tumors in gastrocnemius muscle: a case report. Arch Orthop Trauma Surg; 2008 Jan;128(1):29-31
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  • [Title] Multiple glomus tumors in gastrocnemius muscle: a case report.
  • Glomus tumors are rare benign tumors that account 1-5% of soft tissue tumors of the hand.
  • We describe an unusual case of recurrent glomus tumor located in lower leg.
  • [MeSH-major] Glomus Tumor / diagnosis. Muscle Neoplasms / diagnosis. Muscle, Skeletal. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17624538.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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41. Mentzel T, Kutzner H: Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm. Am J Dermatopathol; 2009 Feb;31(1):44-9
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  • [Title] Dermatomyofibroma: clinicopathologic and immunohistochemical analysis of 56 cases and reappraisal of a rare and distinct cutaneous neoplasm.
  • Dermatomyofibroma represents a rare and distinct benign cutaneous mesenchymal neoplasm of fibroblastic/myofibroblastic differentiation.
  • Histologically, an ill-defined, plaque-like dermal neoplasm of varying cellularity was seen in all cases, composed of bland spindle-shaped tumor cells often oriented parallel to the overlying epidermis.
  • Immunohistochemically, tumor cells in 11 of 48 cases tested stained positively for alpha-smooth muscle actin, and a focal expression of this marker was noted in 20 cases.
  • Dermatomyofibroma represents a benign fibroblastic/myofibroblastic dermal neoplasm.
  • [MeSH-major] Histiocytoma, Benign Fibrous / metabolism. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / metabolism. Skin Neoplasms / pathology

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  • (PMID = 19155724.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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42. Nishi SP, Brey NV, Sanchez RL: Dermal nodular fasciitis: three case reports of the head and neck and literature review. J Cutan Pathol; 2006 May;33(5):378-82
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  • Nodular fasciitis is a benign reactive myofibroblastic proliferative process of unknown etiology.
  • Diagnosis is often a challenge because it may be confused with a malignant tumor due to its aggressive clinical behavior and histological features.
  • The majority of cases arise in the soft tissue, i.e. fascia, muscle, or subcutaneous tissue.
  • [MeSH-major] Fasciitis / pathology. Skin Diseases / pathology

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  • (PMID = 16640547.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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43. Sills ES, Doan TB, Mock RJ, Dixson GR, Rohlfing MB: Immunohistochemical localization patterns for vimentin and other intermediate filaments in calcified ovarian fibrothecoma. Diagn Pathol; 2006;1:28
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  • Endoscopy identified three benign intestinal tubular adenomas.
  • Following laparoscopic excision of the pelvic tumor immunohistochemical analysis of the mass showed negative staining for keratin, S100 protein, inhibin, calretinin, melan A, smooth muscle actin, CD34, CD117, and desmin.
  • CONCLUSION: Ovarian fibrothecomas represent an ovarian stromal neoplasm developing in a wide spectrum of clinical settings.

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  • [Cites] J Med Invest. 2000 Aug;47(3-4):148-51 [11019495.001]
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  • (PMID = 16965622.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1570478
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44. Holub Z, Mára M: [Myomas, fertility and pregnancy]. Ceska Gynekol; 2008 Oct;73(5):307-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Myomas, fertility and pregnancy].
  • OBJECTIVE: The objective of this paper is give to guideline to the management of myoma, fertility and pregnancy.


45. Massoner P, Haag P, Seifarth C, Jurgeit A, Rogatsch H, Doppler W, Bartsch G, Klocker H: Insulin-like growth factor binding protein-3 (IGFBP-3) in the prostate and in prostate cancer: local production, distribution and secretion pattern indicate a role in stromal-epithelial interaction. Prostate; 2008 Aug 1;68(11):1165-78
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  • RESULTS: All cell types of a panel of benign epithelial, stromal and tumor prostate cells expressed IGFBP-3.
  • IGFBP-3 levels were increased in primary tumors but did not differ from benign epithelium in metastases and local recurrent tumors.
  • [MeSH-minor] Cell Communication / physiology. Cell Line, Transformed. Cell Line, Tumor. Coculture Techniques. Fluorescent Antibody Technique. Gene Expression Regulation, Neoplastic. Humans. Insulin-Like Growth Factor Binding Protein 3. Male. Myocytes, Smooth Muscle / cytology. Prostate / metabolism. Prostate / pathology. Prostate / secretion. Reverse Transcriptase Polymerase Chain Reaction. Transforming Growth Factor beta / pharmacology. Up-Regulation / drug effects. Up-Regulation / physiology

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  • [Copyright] Copyright (c) 2008 Wiley-Liss, Inc.
  • (PMID = 18459102.001).
  • [ISSN] 0270-4137
  • [Journal-full-title] The Prostate
  • [ISO-abbreviation] Prostate
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / IGFBP3 protein, human; 0 / Insulin-Like Growth Factor Binding Protein 3; 0 / Insulin-Like Growth Factor Binding Proteins; 0 / Transforming Growth Factor beta
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46. Nikolov A, Nashar S, Jankova J, Jarukova N, Dimitrov A: [Caesarean section by vertical incision of lower uterine segment]. Akush Ginekol (Sofiia); 2009;48(3):3-9
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  • RESULTS. Vertical incision of the uterus is performed in 57.5% due to prematurity and lack of enough space for transversal incision (lower uterine segment not yet formed), in 25 % the cause is situs transverses of the foetus and the rest of the cases are related with technical difficulties in isthmicotransversal approach (myoma praevia, anomalies of the uterus, adhesions of the omentum). C.S. is performed for mean 66 min. in the main group vs. 74 min. with controls (p < 0.05).

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  • (PMID = 20198756.001).
  • [ISSN] 0324-0959
  • [Journal-full-title] Akusherstvo i ginekologii︠a︡
  • [ISO-abbreviation] Akush Ginekol (Sofiia)
  • [Language] bul
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Bulgaria
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47. Kandemir NO, Barut F, Ekinci T, Karagülle C, Ozdamar SO: Intranodal palisaded myofibroblastoma (intranodal hemorrhagic spindle cell tumor with amianthoid fibers): a case report and literature review. Diagn Pathol; 2010;5:12
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  • [Title] Intranodal palisaded myofibroblastoma (intranodal hemorrhagic spindle cell tumor with amianthoid fibers): a case report and literature review.
  • Intranodal palisaded myofibroblastoma (IPM) is a benign mesenchymal neoplasm originating from smooth muscle cells and myofibroblasts.
  • With Masson's trichrome, spindle cells stained as smooth muscle, whereas collagen staining was observed in homogeneous eosinophilic accumulations.
  • IPM is an uncommon neoplasm originating from the stromal component of the lymph node.
  • Although IPM is benign, it is frequently confused with metastatic lesions.
  • [MeSH-major] Lymph Nodes / pathology. Neoplasms, Muscle Tissue / pathology
  • [MeSH-minor] Actins / analysis. Aged, 80 and over. Biomarkers, Tumor / analysis. Cell Proliferation. Groin. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Lymph Node Excision. Male. Staining and Labeling. Vimentin / analysis

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  • (PMID = 20181136.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Ki-67 Antigen; 0 / Vimentin
  • [Other-IDs] NLM/ PMC2829510
  • [General-notes] NLM/ Original DateCompleted: 20100524
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48. Le Corroller T, Kovacs TJ, Champsaur P: Nodular fasciitis with cortical involvement. Joint Bone Spine; 2009 Jan;76(1):101-3
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  • Nodular fasciitis is a commonly encountered benign soft-tissue fibrous tumor that typically involves the upper extremity and may be mistaken for a sarcomatous lesion because of its rapid growth.
  • Lesions of the intramuscular subtype, because of their large size and deep location, usually require preoperative MR-imaging.
  • [MeSH-major] Fasciitis / diagnosis. Muscle, Skeletal / pathology

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  • (PMID = 18993101.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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49. Mavroudis K, Aloumanis K, Papapetrou PD, Voros D, Spanos I: Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle. Fertil Steril; 2007 Jun;87(6):1468.e13-6
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  • [Title] Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle.
  • OBJECTIVE: Virilization due to androgen-secreting neoplasms in women is a result of androgen overproduction from benign or malignant tumors that are found in the ovaries or rarely in the adrenal glands.
  • We describe a very rare case of an ectopic androgen-producing adrenal tumor.
  • RESULT(S): An ectopic mass was detected behind the left iliopsoas muscle.
  • CONCLUSION(S): This case illustrates difficulties in detecting and localizing the rare contingence of an ectopic adrenocortical androgen-secreting tumor.
  • [MeSH-major] Adrenal Gland Neoplasms / surgery. Muscle, Skeletal. Virilism / etiology

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  • (PMID = 17368455.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Sakurai H, Kaji M, Yamazaki K, Suemasu K: Intrathoracic lipomas: their clinicopathological behaviors are not as straightforward as expected. Ann Thorac Surg; 2008 Jul;86(1):261-5
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  • BACKGROUND: Lipomas are a common type of benign tumor, and may involve numerous sites.
  • Symptoms caused by the tumor were seen in only one patient.
  • The resected tumor size ranged from 1.0 to 6.0 cm.
  • Pathologically, three lesions showed an infiltrating type in which mature fat cells were seen between and within muscle or nerve fascicles.
  • One of these three ended in an incomplete resection because the tumor infiltrated the brachial plexus.
  • One patient had a recurrent tumor arising from a resected margin.
  • CONCLUSIONS: Intrathoracic lipomas should be surgically resected if they are detected, because the possibility of liposarcoma or infiltrating development of the tumor cannot be excluded preoperatively.
  • We think that surgical resection of the tumor, rather than conservative management by close observation alone, is a safer treatment.

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  • (PMID = 18573434.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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51. Wang PH, Liu WM, Fuh JL, Chao HT, Chao KC, Yuan CC: Laparoscopic uterine vessel occlusion in the treatment of women with symptomatic uterine myomas with and without adding laparoscopic myomectomy: 4-year results. J Minim Invasive Gynecol; 2008 Nov-Dec;15(6):712-8
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  • [Title] Laparoscopic uterine vessel occlusion in the treatment of women with symptomatic uterine myomas with and without adding laparoscopic myomectomy: 4-year results.
  • STUDY OBJECTIVE: To estimate the necessity of laparoscopic myomectomy (LM) in the treatment of women with symptomatic uterine myomas who are undergoing laparoscopic uterine vessel occlusion (LUVO).
  • DESIGN: A comparative observational study (Canadian Task Force classification II-3).
  • PATIENTS: In all, 163 patients with symptomatic, uncomplicated myomas warranting myomectomy.
  • INTERVENTIONS: Symptomatic myomas treated by LUVO with or without LM.
  • CONCLUSION: Although LUVO is a less invasive procedure in the treatment of most women with symptomatic myomas, it is also less effective for symptom control and has shorter durable symptom relief compared with LUVO+LM.
  • [MeSH-minor] Adult. Female. Humans. Hysterectomy / methods. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Parity. Pregnancy. Retrospective Studies

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  • (PMID = 18971134.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Kawai A, Kadota H, Yamaguchi U, Morimoto Y, Ozaki T, Beppu Y: Blood loss and transfusion associated with musculoskeletal tumor surgery. J Surg Oncol; 2005 Oct 1;92(1):52-8
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  • [Title] Blood loss and transfusion associated with musculoskeletal tumor surgery.
  • BACKGROUND AND OBJECTIVES: No organized data regarding the blood losses associated with musculoskeletal tumor surgery has been existed.
  • The present study aimed to examine the extent of blood loss and the transfusion requirement associated with various kinds of musculoskeletal tumor surgeries in a large, well-defined sample.
  • Wide resections for malignant tumors were associated with significantly more blood loss than marginal resections for benign ones.
  • CONCLUSIONS: Our results provide the first exhaustive data about blood loss and the subsequent need for transfusion associated with various kinds of musculoskeletal tumor surgeries that may be helpful for establishing a guideline for perioperative patient management.
  • [MeSH-major] Blood Loss, Surgical. Blood Transfusion. Bone Neoplasms / surgery. Muscle Neoplasms / surgery

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  • (PMID = 16180233.001).
  • [ISSN] 0022-4790
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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53. Cheng MH, Wang PH: Uterine myoma: a condition amenable to medical therapy? Expert Opin Emerg Drugs; 2008 Mar;13(1):119-33
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  • [Title] Uterine myoma: a condition amenable to medical therapy?
  • BACKGROUND: Uterine myomas are the most common benign tumors of the female reproductive tract.
  • OBJECTIVE: To review the literature on medical treatments that are available or being developed for women with uterine myomas.
  • METHODS: Literature review of articles pertaining to medical therapeutic strategies of uterine myomas. (Articles were searched by means of a computerized PubMed and Cochrane Library search with the following keywords: uterine myomas, leiomyomata, fibroids, and medical treatment.
  • This review will explore the recent advances in medical treatment for the management of uterine myomas.
  • [MeSH-major] Leiomyoma / therapy. Myoma / therapy. Uterine Neoplasms / therapy

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  • (PMID = 18321152.001).
  • [ISSN] 1744-7623
  • [Journal-full-title] Expert opinion on emerging drugs
  • [ISO-abbreviation] Expert Opin Emerg Drugs
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents
  • [Number-of-references] 191
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54. Yan L, Tian Y, Fu Y, Zhao X: Successful pregnancy after fertility-preserving surgery for endometrial stromal sarcoma. Fertil Steril; 2010 Jan;93(1):269.e1-3
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  • PATIENT(S): A 25-year-old woman (gravida 0, para 0) with a misdiagnosis of myoma who received a pathologic diagnosis of endometrial stromal sarcoma after the first surgery.
  • CONCLUSION(S): Endometrial stromal sarcoma is a rare uterine tumor with a poor prognosis.

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  • [Copyright] Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19880109.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Richter C, Baetje M, Bischof A, Makovitzky J, Richter DU, Gerber B, Briese V: Expression of the glycodelin A gene and the detection of its protein in tissues and serum of ovarian carcinoma patients. Anticancer Res; 2007 Jul-Aug;27(4A):2023-5
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  • MATERIALS AND METHODS: We investigated serum, tissue and cyst fluid samples of patients with an ovarian carcinoma in contrast to patients with benign and malignant diseases such as uterine myoma, endometriosis, cervical, uterine and breast cancer, and metastases of bladder and colon carcinoma.
  • CONCLUSION: These results indicate that determination of GdA is not sensitive or specific enough for use as a tumour marker.
  • [MeSH-major] Biomarkers, Tumor / analysis. Gene Expression. Glycoproteins / biosynthesis. Ovarian Neoplasms / diagnosis. Pregnancy Proteins / biosynthesis

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  • (PMID = 17649816.001).
  • [ISSN] 0250-7005
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glycoproteins; 0 / PAEP protein, human; 0 / Pregnancy Proteins; 0 / RNA, Messenger
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56. Kim MD, Lee HS, Lee MH, Kim HJ, Cho JH, Cha SH: Long-term results of symptomatic fibroids treated with uterine artery embolization: in conjunction with MR evaluation. Eur J Radiol; 2010 Feb;73(2):339-44
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  • Tumor regrowth from incomplete infarction was a cause of recurrence in one patient and newly developed leiomyomas in the other one.
  • Of the 14 necrotic myomas on short-term follow up MR after UFE, eight (57.1%) demonstrated maintaining necrosis with further shrinkage and six (42.9%) were no longer visualized on long-term follow up MR images.
  • Long-term MR imaging after UFE revealed persistent necrotic fibroid, non-visualization of fibroids and tumor regrowth when incompletely infarcted.

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  • [Copyright] Copyright (c) 2008 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19084365.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] Ireland
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57. Chen SY, Chang DY, Sheu BC, Torng PL, Huang SC, Hsu WC, Chang WC: Laparoscopic-assisted vaginal hysterectomy with in situ morcellation for large uteri. J Minim Invasive Gynecol; 2008 Sep-Oct;15(5):559-65
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  • DESIGN: Prospective study (Canadian Task Force classification II-1).
  • PATIENTS: In all, 147 women with myoma or adenomyosis weighing more than 500 g from January 2004 through December 2007 were enrolled.

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  • (PMID = 18657481.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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58. Palomba S, Zupi E, Zullo F: Fanfani F, et al. A prospective study of laparoscopy versus minilaparotomy in the treatment of uterine myomas. J Minim Invasive Gynecol; 2006 May-Jun;13(3):253; author reply 253-4
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  • [Title] Fanfani F, et al. A prospective study of laparoscopy versus minilaparotomy in the treatment of uterine myomas.

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  • [CommentOn] J Minim Invasive Gynecol. 2005 Nov-Dec;12(6):470-4 [16337572.001]
  • (PMID = 16698538.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fertility Agents, Female; 33515-09-2 / Gonadotropin-Releasing Hormone
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59. Lee WL, Liu WM, Fuh JL, Tsai YC, Shih CC, Wang PH: Use of uterine vessel occlusion in the management of uterine myomas: two different approaches. Fertil Steril; 2010 Oct;94(5):1875-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of uterine vessel occlusion in the management of uterine myomas: two different approaches.
  • OBJECTIVE: To evaluate the difference between uterine artery occlusion alone (UAO) and combined (UVO) with simultaneous blockage of anastomosis between the uterine and ovarian vessels in the management of women with myomas in a 3-year follow-up.
  • This finding is worthy of further investigation.
  • [MeSH-major] Gynecologic Surgical Procedures / methods. Myoma / surgery. Uterine Artery / surgery. Uterine Neoplasms / surgery. Vascular Surgical Procedures / methods

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  • [Copyright] Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20045514.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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60. Lupattelli T, Clerissi J, Basile A, Minnella DP, Donati Sarti R, Gerli S, Di Renzo G: [Treatment of uterine fibromyoma with bilateral uterine artery embolization: state of the art]. Minerva Ginecol; 2007 Aug;59(4):427-39
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  • The gynecologist is likely to be the primary initial consultant to patients who present with myomas symptoms.

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  • (PMID = 17923833.001).
  • [ISSN] 0026-4784
  • [Journal-full-title] Minerva ginecologica
  • [ISO-abbreviation] Minerva Ginecol
  • [Language] ita
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 72
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61. Bouchelouche K, Alvarez S, Horn T, Nordling J, Bouchelouche P: Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha. Urology; 2006 Jan;67(1):214-9
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  • [Title] Human detrusor smooth muscle cells release interleukin-6, interleukin-8, and RANTES in response to proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha.
  • OBJECTIVES: Recently, we have demonstrated that human detrusor smooth muscle cells in culture secrete the chemokine monocyte chemoattractant protein 1.
  • In the present study, we extended these studies to include the effect of the proinflammatory cytokines tumor necrosis factor (TNF)-alpha and interleukin (IL)-1beta on IL-8, IL-6, and RANTES (regulated on activation, normal T cell expressed and secreted) release by human detrusor smooth muscle cells (HDSMCs) and examined their regulation.
  • METHODS: With ethical approval, detrusor muscle biopsies were obtained from patients with benign noninvasive bladder diseases undergoing control cystoscopy.
  • The new evidence that HDSMCs secrete immunomodulatory proteins makes the detrusor muscle cell a target for anti-inflammatory therapy.
  • [MeSH-major] Chemokine CCL5 / secretion. Interleukin-1 / physiology. Interleukin-6 / secretion. Interleukin-8 / secretion. Muscle, Smooth / cytology. Muscle, Smooth / secretion. Tumor Necrosis Factor-alpha / physiology. Urinary Bladder / cytology. Urinary Bladder / secretion

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  • (PMID = 16413378.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Chemokine CCL5; 0 / Interleukin-1; 0 / Interleukin-6; 0 / Interleukin-8; 0 / Tumor Necrosis Factor-alpha
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62. Kiss S, Gragoudas ES, Dryja TP, Jakobiec FA: Response of choroidal leiomyoma to treatment with proton beam radiation. Retin Cases Brief Rep; 2010;4(2):168-73
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  • PURPOSE: Uveal leiomyoma is a rare, benign smooth muscle neoplasm usually diagnosed only after local resection or enucleation.
  • The neoplasm was treated with a total of 70 cobalt gray equivalents of external proton beam radiation in 5 fractions over 7 days.
  • Biannual follow-up examinations over 3 years showed a funduscopically and ultrasonographically regressing tumor.
  • Microscopic and immunohistochemical examination of the mass revealed a choroidal neoplasm expressing smooth muscle antigens consistent with a uveal leiomyoma.

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  • (PMID = 25390394.001).
  • [ISSN] 1935-1089
  • [Journal-full-title] Retinal cases & brief reports
  • [ISO-abbreviation] Retin Cases Brief Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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63. Ferrero S, Bentivoglio G: Adenomyosis in a patient with mosaic Turner's syndrome. Arch Gynecol Obstet; 2005 Mar;271(3):249-50
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  • At transabdominal ultrasound a myoma (15 x 8.5 x 8 cm) arising from the posterior uterine wall was suspected.
  • Histologic examination confirmed the presence of the myoma and revealed the presence of focal adenomyosis.

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  • (PMID = 15014950.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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64. Carrera JE, Castillo PA, Molina OM: [Lumbar osteochondroma and radicular compression. A case report]. Acta Ortop Mex; 2007 Sep-Oct;21(5):261-6
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  • [Transliterated title] Osteocondroma de lámina lumbar y compresión radicular. Reporte de un caso.
  • Most cartilage forming tumors are benign and rarely affect the spinal canal, their principal location is in humerus metaphysis, femur and tibia.
  • They represent 2% of all tumors and 2.6% of the benign tumors of the spine, usually located at the cervical spine.
  • CASE PRESENTATION: 50-year-old male who began his illness four years ago with pain in the lumbar region with right leg paresthesias, muscle strength 4/5 in the dermatomes L4 and L5, pain was increasing in intensity and frequently.
  • It was performed: total removal of the tumor effectively and symptoms disappeared.

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  • (PMID = 18159915.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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65. Ali AE, Fazl M, Bilbao JM: Primary intracranial leiomyoma: a case report and literature review. Virchows Arch; 2006 Sep;449(3):382-4
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  • However, histologically, the tumor had the characteristic appearance of benign smooth muscle.
  • Benign metastasizing leiomyoma was excluded by thorough imaging.
  • [MeSH-minor] Adult. Biomarkers, Tumor. Brain / pathology. Calmodulin-Binding Proteins / analysis. Cytoplasmic Vesicles / ultrastructure. Female. Humans. Intermediate Filaments / ultrastructure. Magnetic Resonance Imaging

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  • [Cites] Brain Pathol. 1999 Jul;9(3):609-10 [10416997.001]
  • [Cites] Neuroradiology. 1998 Apr;40(4):238-41 [9592794.001]
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  • (PMID = 16896888.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Calmodulin-Binding Proteins
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66. Barroca H, Farinha NJ, Lobo A, Monteiro J, Lopes JM: Deep-seated congenital juvenile xanthogranuloma: report of a case with emphasis on cytologic features. Acta Cytol; 2007 May-Jun;51(3):473-6
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  • BACKGROUND: Juvenile xanthogranuloma (JXG) is a rare, benign non-Langerhans cell histiocytosis that usually occurs in the head, neck or upper trunk of neonates and young children.
  • The surgical specimen histology revealed a JXG with skeletal muscle invasion.
  • Complete reexcision was performed 2 months later after regrowth of the tumor.


67. Plewka A, Madej P, Plewka D, Nowaczyk G, Morek M, Bogunia E, Ciupińska-Kajor M, Sieroń-Stołtny K: The TRAF2 and TRAF6 expression in myomas and myometrium of women in reproduction and perimenopausal age. Folia Histochem Cytobiol; 2010 Sep 30;48(3):407-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The TRAF2 and TRAF6 expression in myomas and myometrium of women in reproduction and perimenopausal age.
  • Uterine myomas represent one of the most common female diseases.
  • Uterine myomas or fibromas are benign, hormone-responding tumours of, respectively, smooth muscles and fibroblasts and their aetiology induces a significant interest.
  • In myomas the presence of aromatase was detected and, in addition, oestrogen was found to be synthesized in myoma cells.
  • The studies were performed on myoma patients of generative age and those in peri-menopausal age.
  • Expression of TRAF2 and TRAF6 proteins was examined using immunohistochemistry and Western blot approach in small and large uterine myomas isolated from women of various age.
  • In addition, the evaluation was conducted at the periphery of every myoma.
  • We indicated that the level of both tested proteins in myomas is higher than in control.
  • TRAF2 level in myometrium was lower than in myomas but higher than in control.

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  • (PMID = 21071347.001).
  • [ISSN] 1897-5631
  • [Journal-full-title] Folia histochemica et cytobiologica
  • [ISO-abbreviation] Folia Histochem. Cytobiol.
  • [Language] ENG
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / TNF Receptor-Associated Factor 2; 0 / TNF Receptor-Associated Factor 6; EC 1.14.14.1 / Aromatase
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68. Ip PP, Cheung AN, Clement PB: Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases. Am J Surg Pathol; 2009 Jul;33(7):992-1005
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases.
  • BACKGROUND: The current World Health Organization classification indicates that a uterine smooth muscle tumor that cannot be histologically diagnosed as unequivocally benign or malignant should be termed "smooth muscle tumor of uncertain malignant potential" (STUMP).
  • DESIGN: The clinicopathologic features of 16 cases of STUMP that exhibited usual smooth muscle differentiation, diagnosed between 1992 and 2006 from 11 hospitals, were studied and classified into 4 subgroups using terminology and criteria described by Stanford investigators.
  • RESULTS: The tumors were classified as follows: 6 as "atypical leiomyoma with limited experience", 7 as "smooth muscle tumor of low malignant potential", 2 as "atypical leiomyoma, low risk of recurrence," and 1 as "mitotically active leiomyoma, limited experience."
  • Only 2 tumors recurred, at 15 and 51 months, respectively; both were atypical leiomyoma with limited experience (multifocal moderate-to-severe atypia, no tumor cell necrosis, and mitotic counts of 4 and 5 mitotic figures /10 high-power fields, respectively).
  • Both tumors had areas that were indistinguishable from benign leiomyoma and both had diffuse immunoreactivity for p16 and p53.
  • Six other tumors that had focal staining for these markers all had a benign outcome.
  • All the other patients were alive and disease-free.
  • CONCLUSIONS: This and other studies suggest that uterine tumors classified as STUMPs using criteria proposed by Stanford investigators are usually clinically benign but should be considered tumors of low malignant potential because they can occasionally recur, in some cases, years after hysterectomy.
  • [MeSH-major] Smooth Muscle Tumor / pathology. Uterine Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cyclin-Dependent Kinase Inhibitor p16 / biosynthesis. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / pathology. Receptors, Estrogen / biosynthesis. Receptors, Progesterone / biosynthesis. Tumor Suppressor Protein p53 / biosynthesis. Ubiquitin-Protein Ligases / biosynthesis

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  • (PMID = 19417585.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / Tumor Suppressor Protein p53; EC 6.3.2.19 / MIB1 ligase, human; EC 6.3.2.19 / Ubiquitin-Protein Ligases
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69. Sinha R, Sundaram M, Lakhotia S, Hegde A: Cervical myomectomy with uterine artery ligation at its origin. J Minim Invasive Gynecol; 2009 Sep-Oct;16(5):604-8
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  • This study was performed to examine the feasibility, blood loss, duration of surgery, and complications in patients with cervical myomas in whom the uterine artery was ligated before myomectomy.
  • Laparoscopic cervical myomectomy was performed in 12 women with cervical myomas and menorrhagia.
  • Myomectomy was subsequently performed, and the myomas were enucleated by incising the capsule anteriorly or posteriorly depending on their location.
  • Even large cervical myomas were removed with minimal blood loss.


70. Reinblatt SL, Krishnamurthy S, Valenti D, Tulandi T: Septic uterus after uterine artery embolization for uterine myomas triggered by endometrial biopsy. J Obstet Gynaecol Can; 2008 Apr;30(4):344-346
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  • [Title] Septic uterus after uterine artery embolization for uterine myomas triggered by endometrial biopsy.
  • Both patients had large and necrotic intramural myomas adjacent to the endometrium.
  • CONCLUSION: Because of the high risk of infection, women with a history of UAE and necrotic myoma adjacent to the endometrium should not undergo endometrial biopsy.
  • We recommend evaluation of the relation of myomas to the endometrium.
  • [MeSH-major] Abscess / etiology. Embolization, Therapeutic / adverse effects. Uterine Diseases / etiology. Uterine Hemorrhage / therapy. Uterus / blood supply

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  • (PMID = 18430385.001).
  • [ISSN] 1701-2163
  • [Journal-full-title] Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
  • [ISO-abbreviation] J Obstet Gynaecol Can
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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71. Hyams ES, Provet J: Angiomyolipoma of the left ureterovesical junction. Rev Urol; 2007;9(2):84-8
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  • Angiomyolipoma (AML) is a benign tumor that typically consists of 3 tissue elements: thick-walled blood vessels, smooth muscle cells, and adipocytes.

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  • [Cites] Br J Radiol. 1998 Sep;71(849):977-9 [10195016.001]
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  • (PMID = 17592543.001).
  • [ISSN] 1523-6161
  • [Journal-full-title] Reviews in urology
  • [ISO-abbreviation] Rev Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1892627
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72. Palade R, Grigoriu M, Voiculescu D: [Gallbladder leiomyoma]. Chirurgia (Bucur); 2006 Jul-Aug;101(4):415-8
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  • [Transliterated title] Leiomiomul de veziculă biliară.
  • Leiomyoma, benign tumor generated by wall's smooth muscle proliferation, is extremely rare revealed.
  • Laparoscopic cholecystectomy is the sufficient and recommended procedure; only even the benignity of the tumor is pathologically established.

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  • (PMID = 17059154.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
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73. Ballesteros Manzo A, Barros Delgadillo JC, Ochoa Rueda S, Villalobos Acosta S, Barroso Villa G, Sánchez Solís V, Gaviño Gaviño F: [Effect of intramural and subserous myomas on in vitro fertilization cycles and their perinatal results]. Ginecol Obstet Mex; 2006 Jan;74(1):55-65
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  • [Title] [Effect of intramural and subserous myomas on in vitro fertilization cycles and their perinatal results].
  • [Transliterated title] Efecto de los miomas intramurales y subserosos en los ciclos de fertilización in vitro y sus resultados perinatales.
  • OBJECTIVE: To evaluate the effect of intramural and subserous myomas in in vitro fertilization cycles, as well as its perinatal results.
  • The variables of size and type of myomas, as well as variables of IVF cycles, implantation and pregnancy rates, and perinatal results were analyzed.
  • We calculated the chi-square test to analyze the relationship between myomas and pregnancy.
  • RESULTS: We analyzed 431 cycles made in 364 patients divided into two groups: study cases (with myomas-65 cycles) and control cases (without myomas-366 cycles).
  • Logistic regression showed that myomas do not affect the possibility of getting pregnant.
  • CONCLUSION: Intramural and subserous myomas < 5 cm do not seem to have an effect in the IVF cycles nor in its perinatal results.
  • In women with myomas < 5 cm that no dot distortion the uterine cavity it is questionable the usefulness of a myomectomy prior to IVF cycles.
  • [MeSH-minor] Adult. Female. Humans. Myoma. Pregnancy. Pregnancy Rate

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  • (PMID = 16634354.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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74. Anderson SE, Nonaka D, Chuai S, Olshen AB, Chi D, Sabbatini P, Soslow RA: p53, epidermal growth factor, and platelet-derived growth factor in uterine leiomyosarcoma and leiomyomas. Int J Gynecol Cancer; 2006 Mar-Apr;16(2):849-53
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  • Uterine leiomyosarcoma (ULMS) is an aggressive gynecological disease.
  • Although ULMS are often found in association with benign leiomyoma (LMA), little is known regarding the relationship between these benign and malignant smooth muscle neoplasms.
  • The objective of this study was to evaluate the expression of epidermal growth factor (EGFR), platelet-derived growth factor (PDGFR), and p53 in ULMS specimens, their prognostic relevance, and the expression of these molecular markers when compared to benign LMA specimens.
  • Tissue microarray was created with three representative cores from each of the ULMS cases as well as from 19 patients with benign uterine leiomyomata.
  • ULMS tumor stage had the strongest association with overall survival (P= 0.05).
  • [MeSH-major] Epidermal Growth Factor / metabolism. Leiomyoma / metabolism. Leiomyosarcoma / metabolism. Platelet-Derived Growth Factor / metabolism. Tumor Suppressor Protein p53 / metabolism. Uterine Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Disease-Free Survival. Female. Humans. Immunoenzyme Techniques. Middle Aged. Survival Rate


75. Squillaci S, Cecchetti D, Tallarigo F, Pontieri F, Filardo AV: [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature]. Pathologica; 2005 Dec;97(6):378-82
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  • [Title] [Myopericytoma-type perivascular myoma located in the soft tissue of the foot: a case report and review of the literature].
  • [Transliterated title] Mioma perivascolare di tipo miopericitoma dei tessuti molli del piede: descrizione di un caso e revisione della letteratura.
  • We describe a rare case of myopericytoma-type perivascular myoma (MTPM) which arose in acral location and the literature on this field is briefly reviewed.
  • Immunohistochemically, the neoplastic cells were positive for vimentin, smooth muscle actin, desmin and calponin, negative for S-100 protein, CD34, CD31 and cytokeratins (AE1/AE3, Cam 5.2).
  • [MeSH-major] Foot Diseases / pathology. Myoma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 16619980.001).
  • [ISSN] 0031-2983
  • [Journal-full-title] Pathologica
  • [ISO-abbreviation] Pathologica
  • [Language] ita
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 16
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76. Ouellet P, Bergeron ME, Lapointe D, Laberge P, Côté M: [Severe hyponatremia associated with transcervical resection of a uterine myoma]. Can J Anaesth; 2010 Feb;57(2):181-2
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  • [Title] [Severe hyponatremia associated with transcervical resection of a uterine myoma].
  • [Transliterated title] Hyponatrémie sévère au cours d'une résection endoscopique d'un myome utérin.

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  • [CommentOn] Can J Anaesth. 2009 Apr;56(4):316-9 [19252964.001]
  • (PMID = 19904578.001).
  • [ISSN] 1496-8975
  • [Journal-full-title] Canadian journal of anaesthesia = Journal canadien d'anesthésie
  • [ISO-abbreviation] Can J Anaesth
  • [Language] fre
  • [Publication-type] Comment; Comparative Study; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anesthetics, General; 0 / Anesthetics, Local; TE7660XO1C / Glycine
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77. Palmara V, Triolo O, Benedetto V, Lo Re C, Sturlese E, Retto G, Santoro G: Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate. Gynecol Obstet Invest; 2010;69(2):131-5
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  • [Title] Morphologic patterns of human endometrial epithelium in women with uterine myomata treated with leuprorelin acetate.
  • AIM: We studied morphologic modifications of the endometrium induced by leuprorelin acetate, a gonadotropin-releasing hormone agonist, in women with uterine myomata.
  • RESULTS: A near-normal endometrium was observed after 2 months of therapy, while treatment with 6 cycles of leuprorelin acetate induced a uniform morphologic regression of the uterine mucosa.


78. Cheng L, Bostwick DG: Atypical sclerosing adenosis of the prostate: a rare mimic of adenocarcinoma. Histopathology; 2010 Apr;56(5):627-31
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  • AIMS: Sclerosing adenosis of the prostate is a benign, small, acinar proliferation in dense spindle cell stroma, with a distinct immunohistochemical profiles.
  • All cases of typical and atypical sclerosing adenosis displayed an intact basal cell layer, which was immunoreactive for high-molecular-weight keratin, S100 protein, smooth muscle actin, and prostate-specific antigen, with no differences between ASA and the control group.
  • ASA is a benign lesion and aggressive treatment is unwarranted.
  • [MeSH-major] Adenocarcinoma / diagnosis. Prostatic Diseases / diagnosis. Prostatic Hyperplasia / diagnosis
  • [MeSH-minor] Aged. Biomarkers, Tumor / metabolism. Biopsy, Needle. Diagnosis, Differential. Humans. Male. Middle Aged. Sclerosis

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  • (PMID = 20459573.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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79. Gavai M, Berkes E, Fekete T, Lazar L, Takacs ZF, Papp Z: Analysis of perioperative morbidity according to whether the uterine cavity is opened or remains closed during abdominal myomectomy--results of 423 abdominal myomectomy cases. Clin Exp Obstet Gynecol; 2008;35(2):107-12
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  • When submucosal myomas are present or multiple fibroids are to be removed, opening the uterine cavity during the surgical procedure is more likely to happen.

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  • (PMID = 18581763.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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81. Litta P, Merlin F, Saccardi C, Pozzan C, Sacco G, Fracas M, Capobianco G, Dessole S: Role of hysteroscopy with endometrial biopsy to rule out endometrial cancer in postmenopausal women with abnormal uterine bleeding. Maturitas; 2005 Feb 14;50(2):117-23
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  • RESULTS: Histological findings for <4 mm level revealed that atrophy was present in 48 (65%) and in 2 cases (2.7%) endometrial cancer was found; for > or = 4 mm values polyps and myomas were present in 86 (59%) and there were 11 (7.5%) endometrial cancer.
  • CONCLUSIONS: In conclusion, endometrial thickness <4 mm can miss malignancies but trans-vaginal ultrasound remains the first line diagnostic procedure in postmenopausal women without AUB, because it is not invasive and has high sensitivity for detecting endometrial cancer and other endometrial disease; according to our experience, outpatient hysteroscopy with biopsy is mandatory in all postmenopausal women with AUB.


82. Zhang L, Liao Q: Effects of testosterone and metformin on glucose metabolism in endometrium. Fertil Steril; 2010 May 1;93(7):2295-8
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  • PATIENT(S): Premenopausal women undergoing total abdominal hysterectomy for uterine myoma or adenomyosis.
  • [MeSH-minor] Adult. Cells, Cultured. Endometriosis / metabolism. Endometriosis / pathology. Epithelial Cells / drug effects. Epithelial Cells / metabolism. Female. Follicular Phase / metabolism. Gene Expression Regulation / drug effects. Glucose Transporter Type 4 / genetics. Glucose Transporter Type 4 / metabolism. Humans. Hypoglycemic Agents / pharmacology. Insulin Receptor Substrate Proteins / genetics. Insulin Receptor Substrate Proteins / metabolism. Leiomyoma / metabolism. Leiomyoma / pathology. Middle Aged. Uterine Diseases / metabolism. Uterine Diseases / pathology. Uterine Neoplasms / metabolism. Uterine Neoplasms / pathology

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  • [Copyright] Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19328476.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Glucose Transporter Type 4; 0 / Hypoglycemic Agents; 0 / IRS1 protein, human; 0 / Insulin Receptor Substrate Proteins; 3XMK78S47O / Testosterone; 9100L32L2N / Metformin; IY9XDZ35W2 / Glucose
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83. Zhu Y, Cuevas IC, Gabriel RA, Su H, Nishimura S, Gao P, Fields A, Hao Q, Young WL, Yang GY, Boudreau NJ: Restoring transcription factor HoxA5 expression inhibits the growth of experimental hemangiomas in the brain. J Neuropathol Exp Neurol; 2009 Jun;68(6):626-32
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  • Hemangiomas are angiogenesis-dependent benign vascular tumors that can rupture and cause intracranial hemorrhages.
  • The EOMA cells induced brain hemangiomas characterized by large cystlike spaces lined by thin walls of endothelial cells surrounded by scant smooth muscle cells.

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  • (PMID = 19458547.001).
  • [ISSN] 0022-3069
  • [Journal-full-title] Journal of neuropathology and experimental neurology
  • [ISO-abbreviation] J. Neuropathol. Exp. Neurol.
  • [Language] ENG
  • [Grant] United States / NINDS NIH HHS / NS / R21 NS050668-02; United States / NINDS NIH HHS / NS / P01 NS044155-05; United States / NINDS NIH HHS / NS / R21 NS050668; United States / NINDS NIH HHS / NS / P01 NS044155; United States / NINDS NIH HHS / NS / R01 NS027713; United States / NINDS NIH HHS / NS / R01 NS27713; United States / NINDS NIH HHS / NS / NS044155-05; United States / NINDS NIH HHS / NS / NS027713-17; United States / NINDS NIH HHS / NS / R21 NS50668; United States / NINDS NIH HHS / NS / P01 NS44145; United States / NINDS NIH HHS / NS / R01 NS027713-17; United States / NINDS NIH HHS / NS / NS050668-02
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Actins; 0 / Hif1a protein, mouse; 0 / Homeodomain Proteins; 0 / Hoxa5 protein, mouse; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Lectins; 0 / Phosphoproteins; 0 / RNA, Messenger; 0 / Thrombospondins; 0 / thrombospondin 2
  • [Other-IDs] NLM/ NIHMS118393; NLM/ PMC2728585
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84. Jha P, Moosavi C, Fanburg-Smith JC: Giant cell fibroblastoma: an update and addition of 86 new cases from the Armed Forces Institute of Pathology, in honor of Dr. Franz M. Enzinger. Ann Diagn Pathol; 2007 Apr;11(2):81-8
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  • A quarter of a century ago at the International Academy of Pathology in Boston, Mass, Drs Enzinger and Shmookler's seminal abstract on giant cell fibroblastoma (GCF) included 20 GCFs on the back and thigh of mostly male children.
  • All cases had benign behavior, but almost half recurred.
  • The caveat was mistaking this tumor for a malignancy.
  • They proposed a relationship of this childhood tumor to dermatofibrosarcoma protuberans (DFSP).
  • Since these original descriptions of GCF, there has been additional immunohistochemical and molecular support for a relationship between DFSP and GCF.
  • Most cases were dermal and subcutaneous, 3 purely dermal, and 5 involved superficial skeletal muscle.
  • Two cases of pure GCF recurred as a hybrid tumor with DFSP areas, one of these with hypercellular DFSP.
  • Most cases studied were positive for CD34 (more intense in DFSP than relatively hypocellular GCF areas) and negative for smooth muscle actin, desmin, HMB-45, keratin, and S100 protein.
  • Additional observations of marked perivascular and onionskin-like chronic inflammation and consistent hemorrhage may aid in the diagnosis of this previously well-described tumor.
  • Collectively, we now have even more convincing morphologic, immunophenotypic, and molecular evidence that GCF is on a spectrum with DFSP.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / metabolism. Child. Child, Preschool. Female. History, 20th Century. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Registries

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  • (PMID = 17349565.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Personal-name-as-subject] Enzinger FM
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85. Kwon YI, Kim TH, Sohn JW, Yoon HJ, Shin DH, Park SS: Benign pulmonary metastasizing leiomvomatosis: case report and a review of the literature. Korean J Intern Med; 2006 Sep;21(3):173-7
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  • [Title] Benign pulmonary metastasizing leiomvomatosis: case report and a review of the literature.
  • She had undergone hysterectomy 16 years previously for uterine myoma.
  • An open lung biopsy revealed tumor that was composed of interlacing bundles of spindle cells with cigar shaped nucleus and eosinophilic myofibrils in the cytoplasm; consistent with multiple leiomyomas.
  • We report here on an interesting case of benign metastasizing leiomyoma (BML) in 51-year-old patient.
  • [MeSH-minor] Disease Progression. Female. Humans. Hysterectomy. Middle Aged. Ovariectomy

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  • (PMID = 17017666.001).
  • [ISSN] 1226-3303
  • [Journal-full-title] The Korean journal of internal medicine
  • [ISO-abbreviation] Korean J. Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 18
  • [Other-IDs] NLM/ PMC3890720
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86. Saitoh M, Hayasaka T, Ohmichi M, Kurachi H, Motoyama T: Primary mucinous adenocarcinoma of the vagina: possibility of differentiating from metastatic adenocarcinomas. Pathol Int; 2005 Jun;55(6):372-5
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  • The patient, a 44-year-old woman, had undergone vaginal total hysterectomy 10 years previously for myoma uteri corporis.
  • The histological features of the vaginal intramural tumor found in this patient resembled those of mucinous adenocarcinoma of the endocervical type.
  • Therefore, it was necessary to determine whether or not the tumor was metastatic from an occult cervical adenocarcinoma.
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Mucin 5AC. Mucin-1 / analysis. Mucin-2. Mucin-6. Mucins / analysis. Neoplasm Metastasis. Vagina / chemistry. Vagina / pathology

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  • (PMID = 15943796.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / MUC2 protein, human; 0 / MUC5AC protein, human; 0 / MUC6 protein, human; 0 / Mucin 5AC; 0 / Mucin-1; 0 / Mucin-2; 0 / Mucin-6; 0 / Mucins
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87. Zhang YX, Chen HL, Ye B, Yang F, Yu LY: [Study on expression and methylation of caveolin 1 gene in non-small cell lung cancers]. Zhonghua Bing Li Xue Za Zhi; 2008 May;37(5):300-4
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  • METHODS: Immunohistochemistry and quanta Qd600 staining were used to detect the expression of Cav-1 in tissues from benign lung lesions (n = 17) and NSCLC (n = 123).
  • RESULTS: Cav-1 protein was highly expressed in cytoplasm and cell membrane of normal bronchial epithelium, alveolar epithelium, endothelial cells, fibroblasts and smooth muscle cells.
  • Amongst the NSCLC group, there was no statistically significant difference in Cav-1 protein expression in different histologic types (P = 0.552) and tumor grades (P = 0.160).
  • On the other hand, Cav-1 protein immunoreactivity was remarkably higher in advanced tumor stage: 72.7% in stage III A + III B, compared with 9.4% in stage I A + I B and 38.3% in stage II A + II B (P = 0.001).
  • CONCLUSIONS: High expression of Cav-1 protein is respected of the aggressive clinical behavior and advanced tumor stage.
  • [MeSH-minor] Aged. DNA Methylation. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging / methods. Somatoform Disorders

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  • (PMID = 18956646.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Caveolin 1
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88. Ławicki S, Bedkowska GE, Gacuta-Szumarska E, Czygier M, Szmitkowski M: [The plasma levels and diagnostic utility of stem cell factor in patients with endometrial cancer and myoma uteri]. Pol Merkur Lekarski; 2009 Jun;26(156):609-15
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  • [Title] [The plasma levels and diagnostic utility of stem cell factor in patients with endometrial cancer and myoma uteri].
  • THE AIM OF THE STUDY: The plasma level and diagnostic utility of SCF have been investigated in endometrial cancer and myoma patients.
  • MATERIAL AND METHODS: The plasma level of SCF and tumor markers like CA 125 and SCC-Ag in endometrial cancer (50 patients), in myoma uteri (25 patients) and in 25 healthy subjects were determined using enzyme-linked immunosorbent assay (ELISA) and chemiluminescence immunoassay (CMIA).
  • RESULTS: SCF plasma level was significantly higher in endometrial cancer patients comparing to the group with myoma and to the control.
  • The diagnostic sensitivity of SCF was slightly lower than CA 125, and was higher in more advanced tumor stage.
  • Positive and negative predictive values were high for SCF and for CA 125, and were higher in more advanced tumor stage.
  • CONCLUSIONS: Our study suggests that tested cytokine (SCF) can be clinically useful in differentiation of endometrial cancer and myoma uteri.
  • [MeSH-major] Biomarkers, Tumor / blood. CA-125 Antigen / blood. Endometrial Neoplasms / blood. Endometrial Neoplasms / diagnosis. Leiomyoma / blood. Leiomyoma / diagnosis. Stem Cell Factor / blood

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  • (PMID = 19711726.001).
  • [ISSN] 1426-9686
  • [Journal-full-title] Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego
  • [ISO-abbreviation] Pol. Merkur. Lekarski
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / Stem Cell Factor
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89. Pejić S, Todorović A, Stojiljković V, Cvetković D, Lucić N, Radojicić RM, Saicić ZS, Pajović SB: Superoxide dismutase and lipid hydroperoxides in blood and endometrial tissue of patients with benign, hyperplastic and malignant endometrium. An Acad Bras Cienc; 2008 Sep;80(3):515-22
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  • [Title] Superoxide dismutase and lipid hydroperoxides in blood and endometrial tissue of patients with benign, hyperplastic and malignant endometrium.
  • The objective of the present study was to examine changes in activities and levels of copper/zinc superoxide dismutase (CuZnSOD) and lipid hydroperoxides (LOOH) in blood and endometrial tissue of patients diagnosed with uterine myoma, endometrial polypus, hyperplasia simplex, hyperplasia complex and adenocarcinoma endometrii.
  • Decrease of both SOD activity and level was found in endometrium of patients with hyperplasia simplex, hyperplasia complex and adenocarcinoma in comparison to women with polypus or myoma.
  • LOOH level was elevated in both tissues of patients with hyperplasia or adenocarcinoma in comparison to healthy subjects or patients with benign diagnosis.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. Humans. Middle Aged. Polyps / blood. Polyps / enzymology. Uterine Neoplasms / blood. Uterine Neoplasms / enzymology

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  • (PMID = 18797802.001).
  • [ISSN] 0001-3765
  • [Journal-full-title] Anais da Academia Brasileira de Ciências
  • [ISO-abbreviation] An. Acad. Bras. Cienc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Lipid Peroxides; EC 1.15.1.1 / Superoxide Dismutase
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90. Gesundheit B, Parkin P, Greenberg M, Baruchel S, Senger C, Kapelushnik J, Smith C, Klement GL: The role of angiogenesis in the transformation of plexiform neurofibroma into malignant peripheral nerve sheath tumors in children with neurofibromatosis type 1. J Pediatr Hematol Oncol; 2010 Oct;32(7):548-53
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  • PURPOSE: The role of angiogenesis in the transformation of peripheral neurofibroma (PNF) to malignant peripheral nerve sheath tumor (MPNST) in neurofibromatosis type 1 (NF1) remains elusive and forms the objective of this study.
  • The role of proangiogenic growth factors such as Vascular Endothelial Growth Factor (VEGF), and its receptors Flk-1 and Flt-1, and vessel maturity, defined as von Willebrand factor (vWf), α-smooth muscle actin+ (SMA+), were evaluated by immuno-histochemistry.
  • In NF and PNF tumor cells were VEGF-, in contrast to VEGF+ tumor cells in MPNST.
  • VEGF receptors also manifested a tumor stage-specific pattern.
  • It permits a pair-wise evaluation of the malignant conversion of benign PNF into its malignant counterpart, in the same patients.

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  • (PMID = 20686424.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / von Willebrand Factor; EC 2.7.10.1 / FLT1 protein, human; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-1; EC 2.7.10.1 / Vascular Endothelial Growth Factor Receptor-2
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91. McLucas B: Collateral supply to uterine leiomyomata from an unnamed vessel: a case report. Minim Invasive Ther Allied Technol; 2009;18(2):106-8
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  • However, myomata have been reported to recruit collateral supply, usually from the ovarian arteries, which may contribute to clinical failure of uterine artery embolization.
  • This case report describes a patient in whom a uterine myoma developed collateral supply de novo.

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  • (PMID = 19255925.001).
  • [ISSN] 1365-2931
  • [Journal-full-title] Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy
  • [ISO-abbreviation] Minim Invasive Ther Allied Technol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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92. Georgiev D, Iankov M, Katsulov A, Vasileva M: [Myoma uteri permagna in pregnancy--a case report and clinical practice]. Akush Ginekol (Sofiia); 2005;44 Suppl 1:6-7
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  • [Title] [Myoma uteri permagna in pregnancy--a case report and clinical practice].


93. Fedele L, Bianchi S, Frontino G: Hormonal treatments for adenomyosis. Best Pract Res Clin Obstet Gynaecol; 2008 Apr;22(2):333-9
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  • Like endometriosis and uterine myomas, adenomyosis presents the typical characteristics of oestrogen-dependent diseases.
  • The medical treatment of adenomyosis is based on the hormonal dependency of the disease and its strongly debated similarities with endometriosis.
  • Although the two diseases have distinct epidemiological features, they have the same 'target tissue' for hormonal therapy, namely ectopic endometrium.
  • Recognized approaches are systemic hormonal treatments, which are generally used for endometriosis and are capable of suppressing the oestrogenic induction of the disease, and local hormonal treatment that targets the ectopic endometrium directly.

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  • (PMID = 17765017.001).
  • [ISSN] 1521-6934
  • [Journal-full-title] Best practice & research. Clinical obstetrics & gynaecology
  • [ISO-abbreviation] Best Pract Res Clin Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Estrogen Antagonists; 33515-09-2 / Gonadotropin-Releasing Hormone; 5W7SIA7YZW / Levonorgestrel; N29QWW3BUO / Danazol
  • [Number-of-references] 39
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94. Sato H, Nanjo H, Tanaka H, Tanaka T: Arias-Stella reaction in an adenomyomatous polyp of the uterus. Acta Obstet Gynecol Scand; 2007;86(1):106-8
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  • A 33-year-old Japanese woman, gravida 1, para 1, presented for an initial prenatal examination at 6-week gestation; ultrasound revealed a myoma-like solid mass in the cervical canal.


95. Kumakiri J, Kikuchi I, Kitade M, Kumakiri Y, Kuroda K, Matsuoka S, Tokita S, Takeda S: Evaluation of factors contributing to uterine scar formation after laparoscopic myomectomy. Acta Obstet Gynecol Scand; 2010 Aug;89(8):1078-83
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  • Factors influencing scar formation in 305 patients with an enucleated solitary myoma.
  • Deformation of the endometrium found by preoperative imaging and complete myometrial penetration during LM had a positive correlation and the number of enucleated myomas a negative correlation with scar formation.
  • Significant factors associated with scar formation were complete myometrial penetration (odds ratio, 2.53; 95% confidence interval, 1.30-4.93; p = 0.006) and enucleation of a subserosal myoma (odds ratio, 0.23; 95% confidence interval, 0.08-0.70; p = 0.009).

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  • (PMID = 20636246.001).
  • [ISSN] 1600-0412
  • [Journal-full-title] Acta obstetricia et gynecologica Scandinavica
  • [ISO-abbreviation] Acta Obstet Gynecol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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96. Junqueira MG, da Silva ID, Nogueira-de-Souza NC, Carvalho CV, Leite DB, Gomes MT, Baracat EC, Lopes LA, Nicolau SM, Gonçalves WJ: Progesterone receptor (PROGINS) polymorphism and the risk of endometrial cancer development. Int J Gynecol Cancer; 2007 Jan-Feb;17(1):229-32
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  • The progesterone receptor gene (PROGINS) has been identified as a risk modifier for benign and malignant gynecological diseases.
  • Regarding the clinical and pathologic findings observed within the group of patients with endometrial cancer, there was significant correlation between T1/T2 genotype and the presence of myoma (P= 0.048).
  • [MeSH-minor] Aged. Alleles. Case-Control Studies. Female. Genetic Predisposition to Disease. Humans. Middle Aged. Neoplasm Staging. Polymorphism, Genetic

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  • (PMID = 17291258.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Progesterone
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97. Martín-Ondarza C, Gil-Moreno A, Torres-Cuesta L, García A, Eyzaguirre F, Díaz-Feijoo B, Xercavins J: Endometrial cancer in polyps: a clinical study of 27 cases. Eur J Gynaecol Oncol; 2005;26(1):55-8
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  • Ultrasonography performed in 22 patients showed images compatible with an endometrial polyp in 50% of cases, myoma in 5%, and inconclusive findings in 45%.

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  • (PMID = 15755002.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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98. Crha I, Pospísil L, Stroblová H, Ventruba P, Záková J, Huser M: [Antibodies against the chlamydial heat shock protein in women with periadnexal adhesions]. Ceska Gynekol; 2006 Mar;71(2):127-31
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  • RESULTS: Twenty-four women (31.6%) had normal finding in small pelvis.
  • Periadnexal adhesions were detected in 43 (56.6%) patients, hydrosalpinx in 13 cases (17.1%), endometriosis in 27 (35.5%) patients and uterine myomas in 11 (145%) women.

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  • (PMID = 16649414.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Chaperonin 60; 0 / Immunoglobulin G
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99. Steiner RA, Fehr PM: [Minimal invasive surgery in gynaecology]. Ther Umsch; 2005 Feb;62(2):127-38
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  • [Transliterated title] Minimal-invasive Chirurgie in der Gynäkologie.
  • Today patients can profit of these new techniques in all fields of gynaecological surgery, some of which are described: The treatment of benign adnexal pathology including ectopic pregnancy is a domain of laparoscopy.
  • Also symptomatic myomas can be enucleated by laparoscopy with favourable pregnancy outcome.
  • The role of endoscopy in malignant disease has still to be defined though pelvic and paraaortal lymphonodectomy and even radical hysterectomy have been shown to be feasible.
  • Pathology of the uterine cavity (myomas, polyps, septae) is routinely treated by hysteroscopy.
  • [MeSH-major] Genital Diseases, Female / surgery. Hysteroscopy. Laparoscopy. Minimally Invasive Surgical Procedures

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  • (PMID = 15756923.001).
  • [ISSN] 0040-5930
  • [Journal-full-title] Therapeutische Umschau. Revue thérapeutique
  • [ISO-abbreviation] Ther Umsch
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 60
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100. Darwish AM, Nasr AM, El-Nashar DA: Evaluation of postmyomectomy uterine scar. J Clin Ultrasound; 2005 May;33(4):181-6
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  • A preoperative myoma size greater than 110 cm(3), the use of a tourniquet, and the experience of the surgeon were significantly correlated with formation of uterine scar hematomas.






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