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Items 1 to 94 of about 94
1. Johnson C, Nagaraj U, Esguerra J, Wasdahl D, Wurzbach D: Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor. Pediatr Radiol; 2007 Jan;37(1):101-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Nasal chondromesenchymal hamartoma: radiographic and histopathologic analysis of a rare pediatric tumor.
  • Nasal chondromesenchymal hamartoma (NCMH) is an extremely rare benign pediatric tumor that was described in 1998.
  • Her medical history was significant for a rare ovarian tumor and pleuropulmonary blastoma.
  • Histologic and immunohistochemical analyses of the tumor were consistent with NCMH.
  • The imaging characteristics of the tumor are reviewed.
  • [MeSH-major] Cartilage Diseases / diagnostic imaging. Hamartoma / diagnostic imaging. Paranasal Sinus Diseases / diagnostic imaging

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  • [CommentIn] Pediatr Radiol. 2011 May;41(5):675-7 [21400084.001]
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  • (PMID = 17091268.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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2. Veras EF, Santamaria IB, Luna MA: Sinonasal chondromyxoid fibroma. Ann Diagn Pathol; 2009 Feb;13(1):41-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondromyxoid fibroma (CMF) is a rare benign cartilaginous tumor that usually arises from the metaphysis of long bones.
  • The initial radiographic findings were suggestive of a vascular tumor or a malignancy, but microscopic examination revealed the typical pathologic features of CMF, and SOX9 immunostaining confirmed its cartilaginous origin.
  • The tumor was successfully excised, and the patient was free of disease at 12-month follow-up.
  • [MeSH-major] Chondroma / pathology. Fibroma / pathology. Nasal Septum / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 19118781.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / SOX9 Transcription Factor; 0 / SOX9 protein, human
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3. Kim HS, Kwon JW, Ahn JH, Chang MJ, Cho EY: Localized tenosynovial giant cell tumor in both knee joints. Skeletal Radiol; 2010 Sep;39(9):923-6
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  • [Title] Localized tenosynovial giant cell tumor in both knee joints.
  • Tenosynovial giant cell tumor, previously called pigmented villonodular synovitis (PVNS), is a rare benign neoplastic process that may involve the synovium of the joint.
  • Herein, we present a case of localized intra-articular tenosynovial giant cell tumor in a 29-year-old man involving both knee joints with a description of the MR imaging and histological findings.
  • [MeSH-major] Cartilage, Articular / pathology. Giant Cell Tumors / pathology. Knee Joint / pathology. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / pathology

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  • (PMID = 20354849.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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4. Karabakhtsian R, Heller D, Hameed M, Bethel C: Periosteal chondroma of the rib--report of a case and literature review. J Pediatr Surg; 2005 Sep;40(9):1505-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Periosteal chondroma is a rare benign tumor of hyaline cartilage.
  • [MeSH-major] Cartilage / pathology. Chondroma / pathology. Ribs / pathology

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  • (PMID = 16150361.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Lucas DR: Osteoblastoma. Arch Pathol Lab Med; 2010 Oct;134(10):1460-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Osteoblastoma is a rare benign bone tumor.
  • It can mimic a variety of other benign bone tumors, but more importantly, distinguishing it from osteoblastoma-like osteosarcoma can be difficult.
  • [MeSH-major] Bone Neoplasms / pathology. Osteoblastoma / pathology. Spinal Neoplasms / pathology
  • [MeSH-minor] Adolescent. Cartilage, Articular / pathology. Cartilage, Articular / radiography. Diagnosis, Differential. Humans. Male. Osteoblasts / pathology. Osteoblasts / radiography. Osteoclasts / pathology. Osteoclasts / radiography. Tomography, X-Ray Computed

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  • (PMID = 20923301.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Kwon H, Kim HY, Jung SN, Sohn WI, Yoo G: Extraskeletal chondroma in the auricle. J Craniofac Surg; 2010 Nov;21(6):1990-1
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Extraskeletal chondroma is a rare benign tumor that develops in soft tissues, and histologically, it is a lobulated nodule surrounded by a fibrous capsule, and the inside consists of mature cartilage cells and diffuse hyalinized matrix.
  • [MeSH-major] Chondroma / diagnosis. Ear Auricle / pathology. Ear Neoplasms / diagnosis

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  • (PMID = 21119479.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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7. Sheff JS, Wang S: Extraskeletal osteochondroma of the foot. J Foot Ankle Surg; 2005 Jan-Feb;44(1):57-9
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  • An extraskeletal osteochondroma is an infrequently encountered benign cartilaginous tumor with a predilection for the hands and feet that usually does not exceed 3 cm in diameter.
  • This diagnosis can be misleading because it bears the same name as the osseous neoplasm more commonly referred to as an exostosis.
  • [MeSH-major] Foot Diseases / pathology. Osteochondroma / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 15704084.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Vujanić GM, Kelsey A, Perlman EJ, Sandstedt B, Beckwith JB: Anaplastic sarcoma of the kidney: a clinicopathologic study of 20 cases of a new entity with polyphenotypic features. Am J Surg Pathol; 2007 Oct;31(10):1459-68
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We report 20 cases of a distinct, previously unrecognized renal neoplasm, anaplastic sarcoma of the kidney with polyphenotypic features.
  • The tumors were identified by re-reviewing tumors with unusual anaplastic features from the National Wilms Tumor Study Pathology Center, the International Society of Pediatric Oncology and the United Kingdom Children's Cancer Study Group trials.
  • Chondroid differentiation was seen in 16 cases, usually in the form of islands of hyaline cartilage (13 cases) or chondroid matrix (3 cases).
  • The nodules of cartilage showed both benign and malignant features, often within the same tumor.
  • Cytokeratin, using the antibody CAM5.2, was uniformly negative within the tumor cells.
  • Tumor stage was known in 15 patients including 7 stage I, 4 stage II, 3 stage III, and 1 stage IV tumors.
  • One patient with stage I tumor developed widespread metastases and died.
  • Five stage I patients were alive and free of tumor at last follow-up.
  • In the differential diagnosis, anaplastic Wilms tumor, primary renal synovial sarcoma, malignant mesenchymoma, ectomesenchymoma, and mesenchymal chondrosarcomas have been considered but none of these tumors shared the same features as the 20 cases described here which represent a distinct clinicopathologic entity with morphologic features of a polyphenotypic anaplastic sarcoma of the kidney.
  • [MeSH-major] Kidney Neoplasms / pathology. Sarcoma / pathology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Child. Child, Preschool. Desmin / analysis. Disease-Free Survival. Female. Gene Expression. Humans. Immunoenzyme Techniques. Infant. Male. Neoplasm Recurrence, Local. Neoplasm Staging. Nephrectomy. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. Phenotype. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Vimentin / analysis

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  • (PMID = 17895746.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Oncogene Proteins, Fusion; 0 / RNA, Messenger; 0 / SYT-SSX fusion protein; 0 / Vimentin
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9. Zustin J, Akpalo H, Gambarotti M, Priemel M, Rueger JM, Luebke AM, Reske D, Lange C, Pueschel K, Lohmann C, Rüther W, Amling M, Alberghini M: Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study. Am J Pathol; 2010 Sep;177(3):1072-8
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  • [Title] Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.
  • Chondromyxoid fibroma represents a rare benign cartilaginous tumor of young patients occurring in a subcortical metaphyseal location.
  • The histogenesis of chondromyxoid fibroma has not yet been postulated, even though the conventional histology and recent immunohistochemical studies on phenotype of the mesenchymal cells and extracellular matrix components suggested its origin in immature cartilage.
  • Therefore, we wished to compare the morphological pattern of immature cartilage tissue with chondromyxoid fibroma to investigate a possible developmental counterpart of chondromyxoid fibroma.
  • Vascularized cartilage canals growing into the fetal cartilage from the perichondrium displayed characteristic glomeruloid structures with central arterioles within the immature mesenchymal stroma and numerous superficial sinusoidal blood vessels accompanied by macrophage infiltration.
  • Based on the observed substantial morphological similarity between the cartilage canals and chondromyxoid fibroma, we suggest that the chondromyxoid fibroma represents a neoplasm originating from or mimicking the fetal cartilage canals within the immature cartilage.
  • [MeSH-major] Cartilage / pathology. Chondroma / pathology. Femoral Neoplasms / pathology. Fibroma / pathology

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  • (PMID = 20671262.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2928941
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10. Almeida G, Silveira F, do Val I, Correa A: Extraosseous vulvar chondroma: a case report. J Reprod Med; 2007 Jan;52(1):35-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Extraosseous chondromas are cartilaginous tissue tumors with a nodular appearance on the hands and feet.
  • Treatment is by surgery and requires removing the tumor with a safety margin.
  • CASE: An 11-year-old girl was referred for a painless solid tumor located on the mons pubis.
  • Surgical removal of the tumor with a safety margin was performed.
  • Macroscopically, the tumor was shiny when cut open and yellowish.
  • Microscopic examination revealed a very distinct cartilage-forming tumor compatible with extraosseous chondroma.
  • CONCLUSION: Extraosseous chondroma is a rare benign tumor.
  • This appears to be the first such report of this type of tumor in this region and age range.

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  • (PMID = 17286066.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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11. Nishihara E, Miyauchi A, Hirokawa M, Kudo T, Ohye H, Ito M, Kubota S, Fukata S, Amino N, Kuma K: Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature. Endocrine; 2006 Oct;30(2):231-6
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  • [Title] Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature.
  • Benign thyroid teratomas are rare in adolescents and adults.
  • We report on three cases of benign thyroid teratomas that presented as painful tumors in the neck after puberty.
  • The tumor adjacent to the thyroid in each case showed rapid enlargement with predominant cystic lesions within several months.
  • Ultrasonography and computed tomography revealed few findings suggesting the origin of the tumor.
  • The patients subsequently underwent resection of the tumor, and microscopic examination revealed various types of tissue including pancreas, adipose, cartilage, muscle, and skin, and the cystic wall was lined by gastric, intestinal, respiratory, and stratified squamous epithelium.
  • Surgical resection was curative, and subsequent histologic examination revealed mature benign teratomas of the thyroid.
  • The main characteristic of our cases presented the painful tumors due to the enlarged cystic formation lined by a variety of different types of epithelium, which agreed with previous cases of benign thyroid teratomas in adolescents and adults.
  • [MeSH-major] Pain / diagnosis. Teratoma / diagnosis. Thyroid Neoplasms / diagnosis. Thyroid Nodule / diagnosis
  • [MeSH-minor] Adolescent. Adult. Female. Humans. Male. Neoplasms / diagnosis

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  • (PMID = 17322585.001).
  • [ISSN] 1355-008X
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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12. Znati K, Ahaouch M, Fatemi H, Chbani L, Affifi A, Kamaoui I, Bennis S, Amarti A: [Femoral metaphyso-diaphyseal chondroblastoma: a case report]. Rev Chir Orthop Reparatrice Appar Mot; 2007 May;93(3):283-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Chondroblastome métaphyso-diaphysaire du fémur: à propos d'un cas.
  • Chondroblastoma is a rare benign tumor of cartilage tissue accounting for less than 1% of all bone tumors.
  • We discuss the anatomic aspects and the clinical course of this rare tumor and present current knowledge of the histogenesis.
  • [MeSH-major] Chondroblastoma / diagnosis. Femoral Neoplasms / diagnosis

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  • (PMID = 17534212.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / S100 Proteins; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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13. Ho L, Stojanovski A, Whetstone H, Wei QX, Mau E, Wunder JS, Alman B: Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors. Cancer Cell; 2009 Aug 4;16(2):126-36
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Gli2 and p53 cooperate to regulate IGFBP-3- mediated chondrocyte apoptosis in the progression from benign to malignant cartilage tumors.
  • Clinical evidence suggests that benign cartilage lesions can progress to malignant chondrosarcoma, but the molecular events in this progression are unknown.
  • Mice that develop benign cartilage lesions due to overexpression of Gli2 in chondrocytes developed lesions similar to chondrosarcomas when they were also deficient in p53.
  • [MeSH-major] Apoptosis / genetics. Bone Neoplasms / pathology. Chondrocytes / pathology. Chondrosarcoma / pathology. Insulin-Like Growth Factor Binding Protein 3 / physiology. Kruppel-Like Transcription Factors / physiology. Tumor Suppressor Protein p53 / physiology

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  • (PMID = 19647223.001).
  • [ISSN] 1878-3686
  • [Journal-full-title] Cancer cell
  • [ISO-abbreviation] Cancer Cell
  • [Language] eng
  • [Databank-accession-numbers] GEO/ GSE15118
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Collagen Type X; 0 / Gli2 protein; 0 / Insulin-Like Growth Factor Binding Protein 3; 0 / Kruppel-Like Transcription Factors; 0 / Somatomedins; 0 / Tumor Suppressor Protein p53
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14. Skinner R, Beall DP, Webb HR, Ly JQ, Fish JR: Calcaneal osteochondroma. J Okla State Med Assoc; 2007 Apr;100(4):120-4
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  • These benign cartilage producing neoplasms are generally asymptomatic and have a relatively small potential for adverse effects.
  • HME, the familial form of this tumor, is associated with a greater incidence of complications, the most significant of which is sarcomatous degeneration to secondary chondrosarcomas.
  • Various imaging techniques can be used to characterize these lesions, but in the absence of symptoms or signs of complications, plain-film radiography is usually sufficient for diagnosis as this tumor has a characteristic radiographic appearance.
  • Once this benign tumor is identified and more serious forms of tumor are ruled out, treatment is generally not needed.
  • [MeSH-major] Bone Neoplasms / pathology. Calcaneus. Exostoses, Multiple Hereditary / pathology. Osteochondroma / pathology

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  • (PMID = 17476996.001).
  • [ISSN] 0030-1876
  • [Journal-full-title] The Journal of the Oklahoma State Medical Association
  • [ISO-abbreviation] J Okla State Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Semenova LA, Bulycheva IV: [Chondromas (enchondroma, periosteal chondroma, enchondromatosis)]. Arkh Patol; 2007 Sep-Oct;69(5):45-8
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  • Chondromas combine a group of benign cartilaginous tissue tumors with common histological manifestations.
  • Chondromas are generally hypocellular, avascular tumors with an abundance of hyaline cartilage matrix and chondrocytes located diffusely, in clones or lobules.
  • Small bone chondromas, Ollier's disease, and Mafucci's syndrome are characterized by the tumor tissue containing a large number of cells and by greater cytological atypia.
  • [MeSH-major] Bone Neoplasms / pathology. Chondrocytes / pathology. Chondroma / pathology. Enchondromatosis / pathology. Extracellular Matrix / pathology. Hyaline Cartilage / pathology

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  • (PMID = 18074822.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Russia (Federation)
  • [Number-of-references] 30
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16. Chatziavramidis A, Grekou A, Thomaidis I, Sidiras T: Myoepithelioma of the larynx: a case report. Cases J; 2009;2:8085
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  • Myoepithelioma of the larynx is a very rare tumor with nonspecific local symptoms.
  • We present the second known case, focusing on the peculiarities of the differential diagnosis for this type of tumor that are crucial for the right histologic diagnosis and furthermore for the therapeutic outcome.We report a 37-year-old male presenting with hoarseness and dyspnea.
  • The indirect laryngoscopy revealed a gross glottic tumor from the right vocal cord who occupied the greater part of the glottis.
  • No apparent cartilage invasion was shown in the CT.
  • A modified vertical partial laryngectomy, under temporary tracheostomy, with muscle reconstruction for the deficit of the right vocal cord was applied for the removal of the tumor.
  • The benign character of the disease in conjunction with its slow progression could delay its detection and diagnosis, leading to a more destructive surgery.

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  • [Cites] Ultrastruct Pathol. 1989 Mar-Jun;13(2-3):187-224 [2544051.001]
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  • (PMID = 19918450.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769400
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17. Luevitoonvechkij S, Arphornchayanon O, Leerapun T, Khunsree S: Periosteal chondroma of the proximal humerus: a case report and review of the literature. J Med Assoc Thai; 2006 Nov;89(11):1970-5
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  • Periosteal chondroma is a slow growing benign cartilaginous tumor of bone.
  • [MeSH-major] Bone Neoplasms / surgery. Chondroma / surgery. Humerus

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  • (PMID = 17205883.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Thailand
  • [Number-of-references] 17
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18. te Winkel ML, Lequin MH, de Bruyn JR, van de Ven CP, de Krijger RR, Pieters R, van den Heuvel-Eibrink MM: Self-limiting sternal tumors of childhood (SELSTOC). Pediatr Blood Cancer; 2010 Jul 15;55(1):81-4
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  • BACKGROUND: Because a sternal mass is often alarming, it is important to identify the clinical features of benign processes.
  • PROCEDURE: Data on clinical presentation, diagnostics, treatment and outcome of pediatric patients presenting with a sternal tumor between 2001 and 2009 were collected from medical records.
  • On radiology, dumbbell-shaped lesions extended to the area behind the sternal bone, involving the cartilage, leading to increased distance between ossification centers.
  • CONCLUSIONS: This study reports 14 young children with a rapidly growing sternal mass due to aseptic inflammation, that we named self-limiting sternal tumor of childhood (SELSTOC).
  • [MeSH-major] Bone Neoplasms / diagnosis. Sternum / pathology

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  • (PMID = 20213849.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Bacterial Agents
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19. Bagga R, Keepanasseril A, Srinivasan R, Dey P, Gainder S, Saha SC, Dhaliwal LK, Patel F: Adenosarcoma of the uterine cervix with heterologous elements: a case report and review of literature. Arch Gynecol Obstet; 2010 Apr;281(4):669-75
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  • INTRODUCTION: Adenosarcoma of the uterus is a rare tumor composed of benign epithelial and malignant stromal components, usually encountered in young women.
  • MATERIALS AND METHODS: We describe a case of mullerian adenosarcoma with heterologous elements of rhabdomyosarcoma and benign cartilage presenting as a cervical polyp in a young girl.
  • [MeSH-major] Adenosarcoma / pathology. Cervix Uteri / pathology. Uterine Cervical Neoplasms / pathology
  • [MeSH-minor] Adolescent. Cartilage / pathology. Female. Humans. Rhabdomyosarcoma / pathology


20. Nyman HT, Nielsen OL, McEvoy FJ, Lee MH, Martinussen T, Hellmén E, Kristensen AT: Comparison of B-mode and Doppler ultrasonographic findings with histologic features of benign and malignant mammary tumors in dogs. Am J Vet Res; 2006 Jun;67(6):985-91
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  • [Title] Comparison of B-mode and Doppler ultrasonographic findings with histologic features of benign and malignant mammary tumors in dogs.
  • OBJECTIVE: To compare and correlate B-mode and color Doppler ultrasonographic characteristics with the histologic findings of benign and malignant mammary tumors in dogs.
  • Paraffin-embedded microsections of the tumors were stained with H&E and examined for presence of necrosis, cysts, cartilage, bone, mineralization, invasion of surrounding tissue, and tissue heterogeneity.
  • RESULTS: Tumor echogenicity and echopattern on ultrasonographic images correlated with tissue heterogeneity detected histologically.
  • Tumor invasion into surrounding tissues as determined ultrasonographically did not correlate with the histologic findings.
  • Data suggest that ultrasonography may have an important role in the evaluation of mammary tumors in dogs, particularly in the evaluation of tissue composition and tumor vascularity.
  • [MeSH-major] Dog Diseases / ultrasonography. Mammary Neoplasms, Animal / ultrasonography

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  • (PMID = 16740091.001).
  • [ISSN] 0002-9645
  • [Journal-full-title] American journal of veterinary research
  • [ISO-abbreviation] Am. J. Vet. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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21. Smith CA, Magenis RE, Himoe E, Smith C, Mansoor A: Chondromyxoid fibroma of the nasal cavity with an interstitial insertion between chromosomes 6 and 19. Cancer Genet Cytogenet; 2006 Dec;171(2):97-100
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  • Chondromyxoid fibroma is an uncommon benign cartilaginous tumor that rarely presents in the sino-nasal region as a locally destructive, erosive lesion.
  • Histology of the tumor, especially with a small sample, can be challenging because of its heterogeneous nature showing an admixture of fibrous, myxoid, and chondroid areas.
  • These results illustrate the distinctive nature of this tumor and may help identify genes involved in the pathogenesis of this tumor.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 6. DNA Transposable Elements. Fibroma / genetics. Nasal Cavity. Nose Neoplasms / genetics. Translocation, Genetic

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  • (PMID = 17116486.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Transposable Elements
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22. Burnei G, Burnei C, Hodorogea D, Gavriliu S, Georgescu I, Vlad C: Osteoarticular reconstructive surgery in malignant bone tumors: the importance of external fixators. J Med Life; 2008 Jul-Sep;1(3):295-306
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  • The patients with malignant bone tumors (table 1.) were studied by sex, tumor type, location, age at the moment of diagnosis, age at the moment of the last evaluation, type of surgery, external fixator implanted, complications, results and survival period.
  • We also considered for each patient the extent of the tumor to diaphysis, soft tissue involvement, involvement of physis and epiphyseal invasion, articular extent, vessels and nerves invasion, presence of metastases and local skin invasion.
  • The development of reconstructive bone surgery is sustained by the possibility to delineate the tumor by diagnosis based on imaging and by the possibility to use modern preoperative and postoperative chemotherapy and radiotherapy.
  • Limb conservation was possible only in aggressive benign tumors up to 1970.
  • Oncologic surgery consists of "en bloc" tumor resection followed by bone reconstruction or modular prosthetic replacement.
  • Modular prosthetic replacement leads to the loss of at least one growing cartilage.
  • [MeSH-major] Bone Neoplasms / surgery. Chondrosarcoma / surgery. External Fixators. Giant Cell Tumor of Bone / surgery. Osteosarcoma / surgery

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  • (PMID = 20108507.001).
  • [ISSN] 1844-122X
  • [Journal-full-title] Journal of medicine and life
  • [ISO-abbreviation] J Med Life
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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23. Wootton-Gorges SL: MR imaging of primary bone tumors and tumor-like conditions in children. Magn Reson Imaging Clin N Am; 2009 Aug;17(3):469-87, vi
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  • [Title] MR imaging of primary bone tumors and tumor-like conditions in children.
  • This article provides a review of the MR imaging features of the major primary malignant and benign bone tumors and tumorlike conditions encountered in the pediatric population.
  • Benign lesions discussed include simple bone cysts, aneurysmal bone cysts, giant cell tumor, osteochondroma, enchondroma, chondroblastoma, osteoid osteoma, osteoblastoma, nonossifying fibroma, fibrous dysplasia, osteofibrous dysplasia, hemangioma, and histiocytosis.
  • [MeSH-major] Bone Neoplasms / diagnosis. Magnetic Resonance Imaging / methods
  • [MeSH-minor] Adolescent. Bone Cysts / diagnosis. Bone Cysts / pathology. Cartilage Diseases / diagnosis. Cartilage Diseases / pathology. Child. Contrast Media. Humans

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  • (PMID = 19524197.001).
  • [ISSN] 1557-9786
  • [Journal-full-title] Magnetic resonance imaging clinics of North America
  • [ISO-abbreviation] Magn Reson Imaging Clin N Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 44
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24. Shelekhova KV, Hejda V, Kazakov DV, Michal M: Mature cystic teratoma of the ovary with male accessory sexual glands including seminal vesicles, prostatic tissue, and bulbo-urethral glands: a case report. Virchows Arch; 2008 Jan;452(1):109-11
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  • We present an extremely rare case of a benign cystic ovarian teratoma with structures of male accessory sexual glands.
  • A unilocular cystic tumor, measuring 5 cm in the largest diameter, was found in her right ovary and was removed.
  • The teratoma contained epidermis, skin appendages, respiratory and intestinal epithelia, cartilage, muscle, and nervous and connective tissue.
  • [MeSH-major] Bulbourethral Glands / pathology. Ovarian Neoplasms / pathology. Prostate / pathology. Seminal Vesicles / pathology. Teratoma / pathology

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  • (PMID = 18066589.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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25. Bancroft LW, Peterson JJ, Kransdorf MJ: MR imaging of tumors and tumor-like lesions of the hip. Magn Reson Imaging Clin N Am; 2005 Nov;13(4):757-74
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  • [Title] MR imaging of tumors and tumor-like lesions of the hip.
  • In conclusion, a wide variety of tumors and tumor-like conditions have a predilection for the hip.
  • The MR imaging signal characteristics and enhancement patterns of malignant and benign hip tumors permit specific diagnoses in some cases.
  • Synovial-based tumor-like processes of the hip can be characterized by MR signal characteristics, such as the hemosiderin within PVNS or the cartilage within synovial chondromatosis.
  • Finally, MR imaging can serve to exclude underlying osseous or soft tissue tumors when radiographs display aggressive features of tumor-like processes.
  • [MeSH-major] Bone Neoplasms / diagnosis. Hip Joint. Magnetic Resonance Imaging / methods. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 16275582.001).
  • [ISSN] 1064-9689
  • [Journal-full-title] Magnetic resonance imaging clinics of North America
  • [ISO-abbreviation] Magn Reson Imaging Clin N Am
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 57
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26. Yildirim C, Rodop O, Kuşkucu M, Sahin O, Gamsizkan M: Giant solitary osteochondroma arising from the fifth metatarsal bone: a case report. J Foot Ankle Surg; 2010 May-Jun;49(3):298.e9-298.e15
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  • Accounting for 20% to 50% of all benign forms, solitary osteochondroma is the most common bone tumor.
  • Osteochondromas are benign osseous neoplasms with a distinct hyaline cartilage cap originating from the physis, and they cease to grow with skeletal maturity.
  • This case demonstrated that, despite the benign nature of the lesion, a large osteochondroma could localize to a metatarsal.
  • [MeSH-major] Bone Neoplasms / pathology. Metatarsal Bones / pathology. Osteochondroma / pathology
  • [MeSH-minor] Biopsy, Needle. Follow-Up Studies. Humans. Immunohistochemistry. Male. Neoplasm Staging. Radiographic Image Enhancement. Risk Assessment. Tomography, X-Ray Computed / methods. Treatment Outcome. Young Adult

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  • [Copyright] Copyright 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20605564.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Donthineni R, Ofluoğlu O: Solitary enchondromas of long bones: pattern of referral and outcome. Acta Orthop Traumatol Turc; 2010;44(5):397-402
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  • OBJECTIVES: Enchondromas are benign cartilaginous tumors, often found incidentally and diagnosed by the radiographic appearance.
  • Very few had the classic signs of an aggressive/growing cartilage tumor.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chondroma / diagnosis. Femur. Humerus. Referral and Consultation

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  • (PMID = 21343691.001).
  • [ISSN] 1017-995X
  • [Journal-full-title] Acta orthopaedica et traumatologica turcica
  • [ISO-abbreviation] Acta Orthop Traumatol Turc
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Turkey
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28. Pelosi G, Rosai J, Viale G: Immunoreactivity for sex steroid hormone receptors in pulmonary hamartomas. Am J Surg Pathol; 2006 Jul;30(7):819-27
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  • No data are available, however, on their expression in pulmonary hamartoma, a benign biphasic tumor consisting of reactive epithelial cells and neoplastic fibromyxoid stroma, cartilage and fat, which shares some morphologic, immunophenotypic, and genotypic features to pleomorphic adenoma of major salivary glands.
  • In conclusion, sex steroid hormone receptor expression is a nonrandom event in pulmonary hamartoma, and may be related to the development and growth of this tumor.

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  • (PMID = 16819323.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Receptors, Androgen; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone; 0 / Receptors, Steroid
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29. Radev BR, Kase JA, Askew MJ, Weiner SD: Potential for thermal damage to articular cartilage by PMMA reconstruction of a bone cavity following tumor excision: A finite element study. J Biomech; 2009 May 29;42(8):1120-6
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  • [Title] Potential for thermal damage to articular cartilage by PMMA reconstruction of a bone cavity following tumor excision: A finite element study.
  • Benign, giant cell tumors are often treated by intralesional excision and reconstruction with polymethylmethacrylate (PMMA) bone cement.
  • The exothermic reaction of the in-situ polymerizing PMMA is believed to beneficially kill remaining tumor cells.
  • However, at issue is the extent of this necrotic effect into the surrounding normal bone and the adjacent articular cartilage.
  • However, as long as there were at least 2mm of uniform subchondral bone above the PMMA implant, the necrotic regions did not extend into the overlying articular cartilage.
  • If the subchondral bone is not of sufficient thickness, or is not continuous, then care should be taken to protect the articular cartilage from thermal damage as a result of the reconstruction of the tumor cavity with PMMA bone cement.
  • [MeSH-major] Bone Cements / toxicity. Bone Neoplasms / surgery. Cartilage, Articular / physiology. Finite Element Analysis. Giant Cell Tumor of Bone / surgery. Polymethyl Methacrylate / toxicity

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  • (PMID = 19344902.001).
  • [ISSN] 1873-2380
  • [Journal-full-title] Journal of biomechanics
  • [ISO-abbreviation] J Biomech
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Cements; 9011-14-7 / Polymethyl Methacrylate
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30. Inaba K, Sakurai Y, Umeki Y, Kanaya S, Komori Y, Uyama I: Laparoscopic excision of subdiaphragmatic bronchogenic cyst occurring in the retroperitoneum: report of a case. Surg Laparosc Endosc Percutan Tech; 2010 Dec;20(6):e199-203
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  • Although bronchogenic cysts (BCs) are benign congenital malformations usually occur in thoracic cavity, retroperitoneal location is extremely uncommon.
  • A 64-year-old Japanese woman was admitted to the hospital because of submucosal tumor in the upper part of the stomach.
  • An upper gastrointestinal endoscopy revealed a submucosal tumor located just distal to the esophagogastric junction.
  • The cystic tumor was completely excised with a laparoscopic procedure.
  • The histologic findings indicated that the cyst was surfaced by the ciliated pseudostratified epithelium without the presence of the cartilage, which was compatible with the BC of the retroperitoneum.

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  • (PMID = 21150402.001).
  • [ISSN] 1534-4908
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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31. Gelderblom H, Hogendoorn PC, Dijkstra SD, van Rijswijk CS, Krol AD, Taminiau AH, Bovée JV: The clinical approach towards chondrosarcoma. Oncologist; 2008 Mar;13(3):320-9
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  • Chondrosarcomas that arise de novo are primary chondrosarcomas, whereas chondrosarcomas developing superimposed on pre-existing benign cartilage neoplasms such as enchondromas or osteochondromas are referred to as secondary chondrosarcomas.
  • [MeSH-major] Bone Neoplasms / therapy. Chondrosarcoma, Mesenchymal / therapy

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  • [ErratumIn] Oncologist. 2008 May;13(5):618
  • (PMID = 18378543.001).
  • [ISSN] 1083-7159
  • [Journal-full-title] The oncologist
  • [ISO-abbreviation] Oncologist
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 91
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32. Kucur M, Isman FK, Balci C, Onal B, Hacibekiroglu M, Ozkan F, Ozkan A: Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia. Urol Oncol; 2008 Jan-Feb;26(1):47-52
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  • [Title] Serum YKL-40 levels and chitotriosidase activity as potential biomarkers in primary prostate cancer and benign prostatic hyperplasia.
  • BACKGROUND: YKL-40, also called human cartilage glycoprotein-39 (HC gp-39) and chitotriosidase are homologs of family 18 glycosyl hydrolases secreted by human macrophages.
  • PURPOSE: The purpose of this study was to compare serum YKL-40 levels and chitotriosidase activity both in benign prostatic hyperplasia and primary prostate cancer.
  • METHODS: YKL-40 and chitotriosidase were determined in serum samples from 93 patients with primary prostate cancer and 61 patients with benign prostatic hyperplasia.
  • CONCLUSION: High serum YKL-40 levels in patients with primary prostate cancer indicate that YKL-40 may have a function in the progression of malignant diseases, whereas no significant elevation was observed in benign prostatic hyperplasia.
  • [MeSH-major] Biomarkers, Tumor / blood. Glycoproteins / blood. Hexosaminidases / blood. Prostatic Hyperplasia / diagnosis. Prostatic Neoplasms / diagnosis


33. Falcone G, Rossi ED, Maccauro G, de Santis V, Rosa MA, Capelli A, Fadda G: Diagnostic relevance of the immunohistochemical detection of growth factors in benign and malignant cartilaginous tumors. Appl Immunohistochem Mol Morphol; 2006 Sep;14(3):334-40
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  • [Title] Diagnostic relevance of the immunohistochemical detection of growth factors in benign and malignant cartilaginous tumors.
  • The goal of this study was to evaluate the diagnostic relevance of the expression of growth factors in cartilaginous tumors and to investigate on the possible correlation with grade, local recurrence, metastatic potential, and survival.
  • Expression of VEGF, PDGF, FGF1, TFGbeta2, TNFalpha, Ki-67, and p53 was analyzed in 21 cases of benign and malignant cartilaginous tumors using immunohistochemistry.
  • These data suggest a progressive modification in the biologic behavior of malignant cartilaginous tumors.

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  • (PMID = 16932026.001).
  • [ISSN] 1541-2016
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Growth Substances
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34. Vincourt JB, Etienne S, Cottet J, Delaunay C, Malanda CB, Lionneton F, Sirveaux F, Netter P, Plénat F, Mainard D, Vignaud JM, Magdalou J: C-propeptides of procollagens I alpha 1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration. Cancer Res; 2010 Jun 1;70(11):4739-48
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  • [Title] C-propeptides of procollagens I alpha 1 and II that differentially accumulate in enchondromas versus chondrosarcomas regulate tumor cell survival and migration.
  • Chondrogenic tumors that exhibit benign or malignant behaviors synthesize variable amounts of cartilage-like extracellular matrix.
  • To define the regulators of these phenotypes, we performed a proteomic comparison of multiple human chondrogenic tumors, which revealed differential accumulation of the C-propeptides of procollagens Ialpha1 and II (PC1CP and PC2CP) in malignant versus benign tumors, respectively.
  • Expression patterns of PC1CP correlated with levels of tumor vascularization, whereas expression patterns of PC2CP suggested its susceptibility to immobilization within the extracellular matrix.
  • Our findings suggest that PC1CP favors angiogenesis and tumor progression, but that PC2CP acts in a more complex manner, exerting antitumor and antiangiogenic properties through apoptosis induction when immobilized, but progression and metastasis when soluble.
  • In summary, the relative levels of PC1CP and PC2CP and their interactions within the extracellular matrix contribute to tumor progression, angiogenesis, and metastasis in chondrogenic tumors.
  • [MeSH-major] Bone Neoplasms / metabolism. Chondroma / metabolism. Chondrosarcoma / metabolism. Collagen Type I / metabolism. Collagen Type II / metabolism

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  • [Copyright] Copyright 2010 AACR.
  • [ErratumIn] Cancer Res. 2010 Jul 1;70(13):5639. Malanda, Bantsimba [corrected to Malanda, Claudie Bantsimba]
  • (PMID = 20460531.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD29; 0 / COL2A1 protein, human; 0 / Collagen Type I; 0 / Collagen Type II; 0 / Disulfides; 0 / Protein Precursors; 0 / Recombinant Proteins; 0 / collagen type I, alpha 1 chain
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35. Wani Y, Notohara K, Tsukayama C, Okumura N: Sclerosing hemangioma with florid endobronchial and endobronchiolar growth. Virchows Arch; 2007 Feb;450(2):221-3
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  • The tumor was 4.8 x 3.5 cm in size, tan-brown, and elastically soft.
  • Furthermore, the main tumor also spread into segmental bronchi and peripheral bronchioles.
  • Microscopically, the tumor consisted of round to cuboidal cells with papillary and solid patterns, partly showing sclerosis and hemorrhage.
  • To form an endobronchial component, it seems to be crucial that the parenchymal SH is located adjacent to the bronchus and involves it, followed by the destruction of the bronchial cartilage.
  • [MeSH-major] Bronchi / pathology. Histiocytoma, Benign Fibrous / pathology

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  • (PMID = 17120028.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
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36. Kubo T, Sugita T, Shimose S, Matsuo T, Arihiro K, Ochi M: Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours. J Bone Joint Surg Br; 2008 Mar;90(3):364-70
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  • [Title] Expression of hypoxia-inducible factor-1alpha and its relationship to tumour angiogenesis and cell proliferation in cartilage tumours.
  • We investigated the use of hypoxia-inducible factor (HIF) proteins as prognostic markers in chondrosarcoma and the relationship of HIF to the biological characteristics of cartilage tumours.
  • The expression of HIF-1alpha, HIF-2alpha, proliferating cell nuclear antigen (PCNA) and microvessel density (MVD) were measured immunohistochemically in 29 specimens of cartilage tumour.
  • There was no HIF-1alpha and HIF-2alpha staining in any of the nine benign cartilage tumours.
  • [MeSH-major] Biomarkers, Tumor / analysis. Chondrosarcoma / metabolism. Chondrosarcoma / pathology. Hypoxia-Inducible Factor 1, alpha Subunit / analysis. Neoplasms, Connective Tissue / metabolism. Neoplasms, Connective Tissue / pathology

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  • (PMID = 18310762.001).
  • [ISSN] 0301-620X
  • [Journal-full-title] The Journal of bone and joint surgery. British volume
  • [ISO-abbreviation] J Bone Joint Surg Br
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Basic Helix-Loop-Helix Transcription Factors; 0 / Biomarkers, Tumor; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / Proliferating Cell Nuclear Antigen; 0 / endothelial PAS domain-containing protein 1
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37. Tiet TD, Hopyan S, Nadesan P, Gokgoz N, Poon R, Lin AC, Yan T, Andrulis IL, Alman BA, Wunder JS: Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation. Am J Pathol; 2006 Jan;168(1):321-30
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  • [Title] Constitutive hedgehog signaling in chondrosarcoma up-regulates tumor cell proliferation.
  • Chondrosarcoma is a malignant cartilage tumor that may arise from benign precursor lesions, such as enchondromas.
  • Treatment with triparanol, an inhibitor of Hedgehog signaling, resulted in a 60% decrease in tumor volume, a 30% decrease in cellularity, and a 20% reduction in proliferation rate.
  • These results show that Hedgehog signaling is active in chondrosarcoma and benign cartilage tumors and regulates tumor cell proliferation.
  • Our data raise the intriguing possibility that Hedgehog blockade could serve as an effective treatment for chondrosarcoma, a tumor for which there are currently no universally effective nonsurgical management options.
  • [MeSH-major] Bone Neoplasms / metabolism. Cell Proliferation. Chondrosarcoma / metabolism. Parathyroid Hormone-Related Protein / metabolism. Signal Transduction / physiology. Trans-Activators / metabolism

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  • (PMID = 16400033.001).
  • [ISSN] 0002-9440
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Gli protein; 0 / Hedgehog Proteins; 0 / Hypolipidemic Agents; 0 / Oncogene Proteins; 0 / Parathyroid Hormone-Related Protein; 0 / Receptors, Cell Surface; 0 / Trans-Activators; 0 / Transcription Factors; 0 / patched receptors; 63S8C3RXGS / Triparanol
  • [Other-IDs] NLM/ PMC1592680
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38. Newton JR, Ruckley RW, Earl UM: Laryngeal neurilemmoma: a case report. Ear Nose Throat J; 2006 Jul;85(7):448-9
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  • Published reports of benign nerve sheath tumors of the larynx are extremely rare.
  • We report a case of a neurilemmoma that arose from the right arytenoid muscle adjacent to the arytenoid cartilage.
  • We discuss the diagnosis and management of this rare tumor.
  • [MeSH-major] Laryngeal Muscles / pathology. Laryngeal Neoplasms / diagnosis. Laryngeal Neoplasms / surgery. Neurilemmoma / diagnosis. Neurilemmoma / surgery
  • [MeSH-minor] Airway Obstruction / prevention & control. Arytenoid Cartilage / pathology. Female. Follow-Up Studies. Humans. Larynx / surgery. Middle Aged. Treatment Outcome

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  • (PMID = 16909818.001).
  • [ISSN] 0145-5613
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Stanić V, Vulović T, Stamenović D, Dordević G: Use of Marlex mesh with methylmethacrylate to repair large full-thickness defects after subtotal sternectomy caused by chondroma. Vojnosanit Pregl; 2008 Feb;65(2):175-7
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  • BACKGROUND: Sternal benign neoplasms are extremely rare.
  • Chondroma is a benign tumor of cartilage and can be single or multple.
  • CASE REPORT: We presented a case of 28-year-old woman with chondroma of the sternum treated by "en bloc" resection of the tumor (subtotal sternectomy).
  • [MeSH-major] Bone Neoplasms / surgery. Chondroma / surgery. Methylmethacrylate. Polypropylenes. Sternum. Surgical Mesh. Thoracic Wall / surgery

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  • (PMID = 18365678.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
  • [Chemical-registry-number] 0 / Polypropylenes; 196OC77688 / Methylmethacrylate
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40. Schrage YM, Machado I, Meijer D, Briaire-de Bruijn I, van den Akker BE, Taminiau AH, Kalinski T, Llombart-Bosch A, Bovée JV: COX-2 expression in chondrosarcoma: a role for celecoxib treatment? Eur J Cancer; 2010 Feb;46(3):616-24
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  • A subset of chondrosarcomas arises secondarily in the benign tumour syndromes enchondromatosis (EC) and multiple osteochondromas (MO), and prevention of tumour development would greatly improve prognosis.
  • COX-2 expression was studied in central- and peripheral cartilaginous tumours.
  • Also the role of high-dose prophylactic celecoxib in preventing the development of benign and malignant cartilage tumours in EC and MO patients deserves further investigation.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Bone Neoplasms / enzymology. Chondrosarcoma / enzymology. Cyclooxygenase 2 / metabolism. Pyrazoles / therapeutic use. Sulfonamides / therapeutic use
  • [MeSH-minor] Animals. Celecoxib. Cell Survival / drug effects. Cyclooxygenase 2 Inhibitors / blood. Cyclooxygenase 2 Inhibitors / therapeutic use. Disease Models, Animal. Drug Evaluation, Preclinical / methods. Humans. Male. Mice. Mice, Nude. Tumor Cells, Cultured. Xenograft Model Antitumor Assays

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  • [Copyright] Copyright (c) 2009 Elsevier Ltd. All rights reserved.
  • (PMID = 20004565.001).
  • [ISSN] 1879-0852
  • [Journal-full-title] European journal of cancer (Oxford, England : 1990)
  • [ISO-abbreviation] Eur. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Cyclooxygenase 2 Inhibitors; 0 / Pyrazoles; 0 / Sulfonamides; EC 1.14.99.1 / Cyclooxygenase 2; JCX84Q7J1L / Celecoxib
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41. Fanburg-Smith JC, Auerbach A, Marwaha JS, Wang Z, Rushing EJ: Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and beta-catenin, Sox9, and osteocalcin immunostaining of 22 cases. Hum Pathol; 2010 May;41(5):653-62
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  • [Title] Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and beta-catenin, Sox9, and osteocalcin immunostaining of 22 cases.
  • Mesenchymal chondrosarcoma, a rare malignant round cell and hyaline cartilage tumor, is most commonly intraosseous but can occur in extraskeletal sites.
  • Immunohistochemistry and follow-up were obtained on mesenchymal chondrosarcoma and tumor controls.
  • The hyaline cartilage in most tumors revealed a consistent linear progression of chondrocyte morphology, from resting to proliferating to hypertrophic chondrocytes.
  • SOX9 was positive in both components of 21 of 22 cases of mesenchymal chondrosarcoma. beta-Catenin highlighted rare nuclei at the interface between round cells and hyaline cartilage in 35% cases.
  • Mesenchymal chondrosarcoma demonstrates centrally located hyaline cartilage with a linear progression of chondrocytes from resting to proliferative to hypertrophic, which undergoes endochondral ossification, recapitulating growth plate cartilage and suggesting that this component of mesenchymal chondrosarcoma may be a differentiated (benign or metaplastic) component of a malignant metastasizing tumor.
  • This hyaline cartilage component is morphologically different from cartilage of control chondrosarcoma.
  • Mesenchymal chondrosarcoma can be separated from small cell osteosarcoma, using Sox 9 for cartilage and osteocalcin for osteoblastic phenotype.
  • Rare nuclear beta-catenin expression at the interface between hyaline cartilage and small round cells potentially implicates the APC/Wnt pathway during endochondral ossification in morphologically benign hyaline cartilage component of mesenchymal chondrosarcoma.
  • [MeSH-major] Bone Neoplasms / pathology. Bone and Bones / pathology. Brain Neoplasms / pathology. Chondrosarcoma, Mesenchymal / pathology. Hyaline Cartilage / pathology. Osteocalcin / metabolism. SOX9 Transcription Factor / metabolism. beta Catenin / metabolism


42. Mnif H, Koubaa M, Zrig M, Zammel N, Abid A: Peroneal nerve palsy resulting from fibular head osteochondroma. Orthopedics; 2009 Jul;32(7):528
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  • The patient underwent surgical decompression of the right peroneal nerve after resection of the bone tumor.
  • Osteochondroma is a benign tumor consisting of projecting bone capped by cartilage.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / surgery. Fibula / surgery. Osteochondroma / complications. Osteochondroma / surgery. Peroneal Neuropathies / etiology. Peroneal Neuropathies / surgery

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  • (PMID = 19634838.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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43. Riddle ND, Gorden L, Rojiani MV, Hakam A, Rojiani AM: CD44 and p53 immunoexpression patterns in NF1 neoplasms - indicators of malignancy and infiltration. Int J Clin Exp Pathol; 2010;3(5):515-21
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  • [Title] CD44 and p53 immunoexpression patterns in NF1 neoplasms - indicators of malignancy and infiltration.
  • The tumor suppressor gene, p53, has also been implicated in malignant progression of various human tumors including malignant peripheral nerve sheath tumors (MPNST).
  • Thirteen of 28 (46%) benign neurofibroma also had some expression of p53 above 'normal level', although much lower than the MPNST.
  • Plexiform neurofibroma did not differ from other benign lesions in their expression of p53.
  • 70% of benign neurofibroma demonstrated some, usually focal, CD44 positivity.
  • CD44v6 expression was positive in control tissues but was not identified in any of tumor samples.
  • This is interpreted as a reflection of the interaction of CD44+ tumor cells with extracellular matrix, hence facilitating infiltrative behavior.
  • [MeSH-major] Antigens, CD44 / biosynthesis. Neurofibromatosis 1 / metabolism. Neurofibromatosis 1 / pathology. Tumor Suppressor Protein p53 / biosynthesis
  • [MeSH-minor] Biomarkers, Tumor / analysis. Disease Progression. Gene Expression. Gene Expression Profiling. Humans. Immunohistochemistry

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  • (PMID = 20606732.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD44; 0 / Biomarkers, Tumor; 0 / Tumor Suppressor Protein p53
  • [Other-IDs] NLM/ PMC2897111
  • [Keywords] NOTNLM ; CD44 / Neurofibromatosis type 1 (NF1) / immunohistochemistry / infiltration / p53 / tumor markers
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44. Budny AM, Ismail A, Osher L: Chondromyxoid fibroma. J Foot Ankle Surg; 2008 Mar-Apr;47(2):153-9
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  • Chondromyxoid fibroma is an uncommon benign cartilaginous tumor accounting for less than 1% of all bone tumors.

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  • (PMID = 18312923.001).
  • [ISSN] 1067-2516
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Mortazavi SM, Wenger D, Asadollahi S, Shariat Torbaghan S, Unni KK, Saberi S: Periosteal osteoblastoma: report of a case with a rare histopathologic presentation and review of the literature. Skeletal Radiol; 2007 Mar;36(3):259-64
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  • Osteoblastoma is an uncommon benign bone tumor most commonly located in the vertebral column or metaphysis of a long bone.
  • Plate-like arrangements of cartilage in the margin of the neoplastic tissue were also identified.
  • Although extremely unusual, the presence of cartilage does not necessarily exclude the diagnosis of osteoblastoma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Knee Joint / pathology. Osteoblastoma / diagnosis. Periosteum / pathology

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  • (PMID = 16868789.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 29
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46. Haskell HD, Butt KM, Woo SB: Pleomorphic adenoma with extensive lipometaplasia: report of three cases. Am J Surg Pathol; 2005 Oct;29(10):1389-93
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  • In addition, one case consists of a proliferation of spindle cells with an interesting combination of mature adipose tissue, hyaline cartilage, and bone in the absence of ductal structures.
  • The differential diagnosis, as it pertains to other fat-containing tumors (such as lipoadenoma, spindle cell lipoma, interstitial lipomatosis, and benign mesenchymoma), is discussed.
  • It is likely that the ability of myoepithelial cells to undergo various metaplasias is the cause of the unusual histologic appearances of this tumor.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Adipocytes / pathology. Parotid Neoplasms / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands, Minor / pathology

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  • (PMID = 16160483.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Fraquet N, Faizon G, Rosset P, Phillipeau J-, Waast D, Gouin F: Long bones giant cells tumors: treatment by curretage and cavity filling cementation. Orthop Traumatol Surg Res; 2009 Oct;95(6):402-6
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  • OBJECTIVE: Giant cell tumors (GCT) of bone are benign tumors with local aggressiveness that most of the time occur around the metaphyseal area of long bones, often in contact with the articular cartilage.
  • Preoperative radiological evaluation with standard X-rays showed that the tumor measured a mean 71x45mm, for a mean volume of 78cm(3).
  • Seventy-three percent of these GCT were in direct contact with the articular cartilage and 40% extended to the soft tissues as seen on the CAT scan and/or MRI.
  • [MeSH-major] Bone Cements / therapeutic use. Bone Neoplasms / surgery. Femur / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Tibia / surgery

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  • [Copyright] 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 19767256.001).
  • [ISSN] 1877-0568
  • [Journal-full-title] Orthopaedics & traumatology, surgery & research : OTSR
  • [ISO-abbreviation] Orthop Traumatol Surg Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Bone Cements
  • [General-notes] NLM/ Original DateCompleted: 20100201
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48. Gajewski DA, Burnette JB, Murphey MD, Temple HT: Differentiating clinical and radiographic features of enchondroma and secondary chondrosarcoma in the foot. Foot Ankle Int; 2006 Apr;27(4):240-4
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  • BACKGROUND: Enchondroma is the most common benign tumor of the bones of the foot.
  • Concern for malignant change is warranted for cartilage bone tumors of the foot if they exceed 5 cm(2), or if they arise in the midfoot or hindfoot.
  • [MeSH-major] Bone Neoplasms / diagnostic imaging. Bone Neoplasms / pathology. Chondroma / diagnostic imaging. Chondroma / pathology. Chondrosarcoma / diagnostic imaging. Chondrosarcoma / pathology


49. Pelosi G, Rodriguez J, Viale G, Rosai J: Salivary gland-type tumors with myoepithelial differentiation arising in pulmonary hamartoma: report of 2 cases of a hitherto unrecognized association. Am J Surg Pathol; 2006 Mar;30(3):375-87
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  • Reported is a hitherto unrecognized association of pulmonary hamartomas with salivary gland-type tumors showing myoepithelial differentiation, namely, a case of myoepithelioma arising in a otherwise classic hamartoma with cartilage predominance, and a case of malignant mixed tumor arising in a predominantly fibrous hamartoma resembling müllerian adenofibroma.
  • The myoepithelioma patient was well with no signs of recurrent disease at 6-month clinical control, but she was then lost to follow-up; the malignant mixed tumor patient is alive and well after 6 months since operation.
  • The lack of individual cell necrosis, mitotic activity, cell atypia, and pulmonary parenchyma infiltration supported a diagnosis of benign or unproven malignant potential tumor for the myoepithelioma, whereas the reverse held true for the other tumor in which the diagnosis of malignant mixed tumor of the lung was rendered.
  • [MeSH-major] Hamartoma / pathology. Lung Neoplasms / pathology. Mixed Tumor, Malignant / pathology. Myoepithelioma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor. Biopsy, Needle. Cell Transformation, Neoplastic. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Lung Diseases / metabolism. Lung Diseases / pathology. Lung Diseases / surgery. Salivary Glands / pathology

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  • (PMID = 16538059.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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50. Benbenisty KM, Andea A, Metcalf J, Cook J: Atypical cellular neurothekeoma treated with Mohs micrographic surgery. Dermatol Surg; 2006 Apr;32(4):582-7; discussion 587
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  • BACKGROUND: Atypical cellular neurothekeoma is a rare neoplasm generally regarded as a benign tumor with locally aggressive behavior.
  • RESULTS: The neoplasm was extirpated in a three-stage, five section Mohs surgery procedure.
  • The resulting defect was repaired by a two-stage, pedicled nasolabial transposition flap with a cartilage graft taken from the ipsilateral ear.
  • Debate in the literature is ongoing regarding the true histogenesis of this rare tumor.
  • Because of this tumor's local destructive behavior and propensity to recur with inadequate resection, we recommend Moths micrographic surgery for the treatment of cellular neurothekeomas.
  • [MeSH-major] Mohs Surgery. Neurothekeoma / surgery. Nose Neoplasms / surgery

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  • [CommentIn] Dermatol Surg. 2008 Mar;34(3):428 [18248473.001]
  • (PMID = 16681671.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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51. Song SY, Noh JH, Lee SJ, Son HJ: Bronchogenic cyst of the stomach masquerading as benign stromal tumor. Pathol Int; 2005 Feb;55(2):87-91
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  • [Title] Bronchogenic cyst of the stomach masquerading as benign stromal tumor.
  • Neither cartilage nor gastrointestinal epithelium was identified.
  • [MeSH-major] Bronchogenic Cyst / pathology. Gastrointestinal Stromal Tumors / diagnosis. Stomach Diseases / pathology. Stomach Neoplasms / diagnosis


52. Stieber JR, Dormans JP: Manifestations of hereditary multiple exostoses. J Am Acad Orthop Surg; 2005 Mar-Apr;13(2):110-20
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  • The solitary osteochondroma, a common pediatric bone tumor, is a cartilage-capped exostosis.
  • Although exostoses are benign lesions, they are often associated with characteristic progressive skeletal deformities and may cause clinical symptoms.
  • Patients with hereditary multiple exostosis have a slight risk of sarcomatous transformation of the cartilaginous portion of the exostosis.


53. Morozov A, Downey RJ, Healey J, Moreira AL, Lou E, Franceschino A, Dogan Y, Leung R, Edgar M, LaQuaglia M, Maki RG, Moore MA: Benign mesenchymal stromal cells in human sarcomas. Clin Cancer Res; 2010 Dec 1;16(23):5630-40
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  • [Title] Benign mesenchymal stromal cells in human sarcomas.
  • We further characterized primary cultures as either benign or malignant by the presence of tumor-defining genetic lesions and tumor formation in immunocompromised mice.
  • RESULTS: We show that a dedifferentiated liposarcoma cell line DDLS8817 posesses fat, bone, and cartilage trilineage differentiation potential characteristic of MSCs.
  • Surprisingly, many of these cultures are benign, as they do not form tumors in mice and lack sarcoma-defining genetic lesions.
  • Consistent with the recently proposed pericyte origin of MSCs in normal human tissues, sarcoma-derived benign MSCs (SDBMSCs) express markers of pericytes and cooperate with endothelial cells in tube formation assays.
  • CONCLUSIONS: SDBMSCs/pericytes represent a previously undescribed stromal cell type in sarcoma that may contribute to tumor formation.

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  • [Copyright] ©2010 AACR.
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  • (PMID = 21138865.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / KL2 RR024997; United States / NCRR NIH HHS / RR / RR024997-01; United States / NCRR NIH HHS / RR / KL2RR024997
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Il2rg protein, mouse; 0 / Interleukin Receptor Common gamma Subunit
  • [Other-IDs] NLM/ NIHMS224015; NLM/ PMC3820159
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54. Kim WJ, Kim KJ, Lee SK, Choy WS: Solitary pelvic osteochondroma causing L5 nerve root compression. Orthopedics; 2009 Dec;32(12):922
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  • Osteochondroma is the most common benign bone tumor, accounting for more than one-third of all benign bone tumors.
  • Thus, surgical excision is not routinely recommended unless the tumor causes clinical symptoms or cosmetic distress.
  • An exostotic bony projection composed of dense calcification of the cartilaginous cap arose from the iliac crest, which was located just lateral to the right sacroiliac joint in the paravertebral area, L5 level.
  • Magnetic resonance imaging showed an irregular, exophytic outgrowing calcified mass with cartilage cap and exostotic mass compressed to the proximal part of the right L5 nerve root lateral to the nerve root foramen.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / surgery. Decompression, Surgical / methods. Osteochondroma / complications. Osteochondroma / surgery. Pelvic Bones / radiography. Pelvic Bones / surgery. Radiculopathy / etiology. Radiculopathy / surgery

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  • [Copyright] Copyright 2009, SLACK Incorporated.
  • (PMID = 19968229.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. van den Brink-Knol H, van Esch E: Spontaneous malignant mixed Müllerian tumor in a Wistar rat: a case report including immunohistochemistry. Vet Pathol; 2010 Nov;47(6):1105-10
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  • [Title] Spontaneous malignant mixed Müllerian tumor in a Wistar rat: a case report including immunohistochemistry.
  • This report presents a rare, spontaneous, heterologous, malignant mixed Müllerian tumor observed in a 98-week-old untreated Wistar rat.
  • The solid part exhibited characteristics of a highly infiltrative adenocarcinoma, whereas the composition of the polypoid mass was heterogeneous, consisting of a variety of benign and malignant epithelial and mesenchymal elements.
  • The mesenchymal components consisted of well-differentiated cartilage and bone along with chondrosarcomatous, rhabdomyomatous, and other mesenchymal elements.
  • Immunohistochemical analysis further supported the diagnosis of malignant mixed Müllerian tumor.
  • [MeSH-major] Mixed Tumor, Mullerian / veterinary. Rats, Wistar. Uterine Neoplasms / veterinary

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  • (PMID = 20587687.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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56. Finitsis S, Giavroglou C, Potsi S, Constantinidis I, Mpaltatzidis A, Rachovitsas D, Tzioufa V: Nasal chondromesenchymal hamartoma in a child. Cardiovasc Intervent Radiol; 2009 May;32(3):593-7
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  • Nasal chondromesenchymal hamartoma (NCMH) is a benign tumor that was described in 1998.
  • The tumor was completely resected surgically.
  • Histopathology and immunohistochemical analyses of the tumor disclosed a NCMH.
  • The imaging characteristics of the tumor are described and the radiology literature is reviewed.
  • [MeSH-major] Cartilage Diseases / diagnosis. Hamartoma / diagnosis. Nose Diseases / diagnosis

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  • (PMID = 18972159.001).
  • [ISSN] 1432-086X
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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57. Jin MS, Ha HJ, Baek HJ, Lee JC, Koh JS: Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report. Acta Cytol; 2008 May-Jun;52(3):357-60
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  • [Title] Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report.
  • BACKGROUND: Typical cytologic features of pulmonary hamartoma (PH) are usually smears of hyaline cartilage, fibrous tissue, smooth muscle, adipocytic components and respiratory epithelium.
  • Cytologic features of adenomyomatous hamartoma, a special variant of PH, are not documented in the literature and are confused with epithelial neoplasm in the case of sparse stromal cellularity.
  • Fine needle aspiration biopsy (FNAB) revealed numerous mucinous epithelial cells presenting predominantly in cohesive cellular sheets that suggested benign mucinous epithelial lesion.
  • The patient underwent surgery for the tumor, and it was histologically proven to be an adenomyomatous hamartoma.
  • [MeSH-major] Biopsy, Fine-Needle. Hamartoma / diagnosis. Lung Neoplasms / diagnosis

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  • (PMID = 18540306.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Káram-Orantes M, Fonte-Avalos V, Zuloaga-Salcedo S, Domínguez-Cherit J: [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006]. Gac Med Mex; 2007 Sep-Oct;143(5):371-5
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  • [Title] [Frequency of benign tumors at the Hospital General "Dr. Manuel Gea Gonzalez". Record review between 2000-2006].
  • [Transliterated title] Frecuencia de tumores benignos durante el periodo de 2000-2006 en el Hospital General "Dr. Manuel Gea González".
  • BACKGROUND: Benign skin neoplasms are defined as autonomous growing tissue unrelated to normal growing of the skin, that persist even after the originating stimulus dissapears.
  • Almost all human beings have a certain number of benign cutaneous neoplasms and many never seek medical attention.
  • The aim of this study was to record the number of benign tumors studied at the Dermatology Department of a medical facility.
  • We included year of admission, number of biopsies, sex, age, tumor location, histological and clinical diagnoses.
  • RESULTS: We analyzed 9,436 biopsies of which 3,765 constituted benign neoplasms; 595 were not included and our total sample was 3,170 tumors.
  • The most frequent tumors according to histopathological diagnoses in descending order were: melanocytic, cutaneous cysts, fibrous tumors, vascular tumors, epidermal tumors, fat tumors, tumors with hair differentiation, neural tumors, glandular tumors, tumors with sebaceous differentiation, cartilage and bone tumors, and smooth muscle tumors.
  • The most common benign tumors were: Melanocytic nevi, epidermal cysts, seborrheic keratoses, pyogenic granulomas, lipomas and dermatofibromas.
  • CONCLUSIONS: Melanocytes represented by melanocytic nevi (junctional, intradermic and compound) were the most frequent benign neoplasms, followed by epidermoid cysts.
  • Our results illustrate the most common benign tumors observed in a dermatology department.
  • [MeSH-major] Neoplasms / epidemiology

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  • (PMID = 18246930.001).
  • [ISSN] 0016-3813
  • [Journal-full-title] Gaceta médica de México
  • [ISO-abbreviation] Gac Med Mex
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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59. Yang SW, Lin CY: A peculiar site of chondroma: the epiglottis. Acta Otolaryngol; 2005 Aug;125(8):906-9
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  • Chondroma of the laryngeal cartilage is an uncommon benign cartilaginous neoplasm.
  • The commonest location is the posterior lamina of the cricoid cartilage, followed by the thyroid cartilage.
  • We present this case to highlight the occurrence of this rare benign lesion in the epiglottis, and stress that it should not be neglected in the differential diagnosis of an epiglottic mass.
  • [MeSH-major] Chondroma / diagnosis. Epiglottis / surgery. Laryngeal Neoplasms / diagnosis

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  • (PMID = 16158541.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Norway
  • [Number-of-references] 11
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60. Chen C, Zhou H, Xu L, Liu X, Liu Z, Ma D, Chen Y, Ma Q: Prognostic significance of downregulated expression of programmed cell death 5 in chondrosarcoma. J Surg Oncol; 2010 Dec 1;102(7):838-43
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  • METHODS: The mRNA and protein levels of PDCD5 in chondrosarcoma and matched corresponding non-tumor tissues were evaluated by real-time PCR and Western blot, respectively.
  • RESULTS: The mRNA and protein levels of PDCD5 were significantly decreased in chondrosarcoma compared with corresponding non-tumor tissues.
  • Low expression of PDCD5 protein was 61.8% (21/34) in chondrosarcomas, as compared 12.5% (1/8) in normal bones, as well as compared 23.5% (4/17) in benign cartilage tumors.
  • [MeSH-major] Apoptosis Regulatory Proteins / genetics. Bone Neoplasms / genetics. Bone and Bones / metabolism. Chondrosarcoma / genetics. Neoplasm Proteins / genetics
  • [MeSH-minor] Apoptosis. Blotting, Western. Case-Control Studies. Down-Regulation. Follow-Up Studies. Humans. Immunoenzyme Techniques. Neoplasm Staging. Prognosis. RNA, Messenger / genetics. Reverse Transcriptase Polymerase Chain Reaction. Survival Rate

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  • [Copyright] 2010 Wiley-Liss, Inc.
  • (PMID = 20872801.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Neoplasm Proteins; 0 / PDCD5 protein, human; 0 / RNA, Messenger
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61. Kanngurn S, Somran J, Art-Ong C, Lamlertthon W, Porncharoenpong S: Primary peritoneal adenosarcoma with stromal overgrowth and fetal type cartilage: a case report and literature review. J Med Assoc Thai; 2005 Jun;88(6):849-54
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  • [Title] Primary peritoneal adenosarcoma with stromal overgrowth and fetal type cartilage: a case report and literature review.
  • Primary peritoneal adenosarcoma with sarcomatous overgrowth and fetal-type cartilage presented in a 48-year-old female patient is described.
  • The tumor seems likely to have derived from the pelvic peritoneum, wheareas the uterus, ovaries and tubes were uninvolved.
  • It was composed of benign-appearing glands and a sarcomatous component showing cartilaginous differentiation.
  • [MeSH-major] Adenosarcoma / pathology. Cartilage / pathology. Peritoneal Neoplasms / pathology

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  • (PMID = 16083229.001).
  • [ISSN] 0125-2208
  • [Journal-full-title] Journal of the Medical Association of Thailand = Chotmaihet thangphaet
  • [ISO-abbreviation] J Med Assoc Thai
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Thailand
  • [Number-of-references] 22
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62. Sohn SH, Koh SA, Kim DG, Park SW, Lee KH, Kim MK, Choi JH, Hyun MS: A case of spine origin chondroblastoma metastasis to lung. Cancer Res Treat; 2009 Dec;41(4):241-4
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  • Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur.
  • Unlike previously published examples of metastatic chondroblastoma, these metastasis developed before any operative manipulation of the primary tumor.
  • And primary tumor site was also unusual.

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  • (PMID = 20057972.001).
  • [ISSN] 2005-9256
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2802843
  • [Keywords] NOTNLM ; Chondroblastoma / Lung metastasis / Spine origin
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63. Rodriguez FJ, Aubry MC, Tazelaar HD, Slezak J, Carney JA: Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma. Am J Surg Pathol; 2007 Dec;31(12):1844-53
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  • [Title] Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma.
  • The Carney triad is the clinical association of gastric stromal sarcomas, pulmonary cartilaginous tumors, and extra-adrenal paragangliomas.
  • The pulmonary tumors are its second commonest component and have been misinterpreted clinically and pathologically as metastases from the gastric tumors and pulmonary cartilaginous hamartomas, respectively.
  • They have not been previously described in detail in the pathology literature or compared with pulmonary cartilaginous hamartomas.
  • Forty-two patients with pulmonary cartilaginous tumors as a component of Carney triad were identified.
  • Hematoxylin and eosin-stained sections of the neoplasms were evaluated for a series of histologic features.
  • A subgroup of 41 tumors from the latter was compared with those in a group of pulmonary cartilaginous hamartomas.
  • Their pulmonary neoplasm(s) were usually asymptomatic, often multiple, well circumscribed, medium-sized (mean diameter=2.8 cm), and composed almost exclusively of cartilage and bone surrounded by a fibrous pseudocapsule.
  • The cartilage was usually myxoid, less frequently hyaline, and commonly calcified, ossified, or both.
  • The pulmonary neoplasms in the Carney triad are well-differentiated benign cartilaginous tumors that are best designated as chondromas.
  • They differ pathologically from pulmonary cartilaginous hamartomas on the basis of the presence of a thin fibrous pseudocapsule, frequent bone metaplasia, and calcification, and also the absence of entrapped epithelium and fat.
  • [MeSH-major] Chondroma / pathology. Hamartoma / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology

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  • (PMID = 18043038.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Hondar Wu HT, Chen W, Lee O, Chang CY: Imaging and pathological correlation of soft-tissue chondroma: a serial five-case study and literature review. Clin Imaging; 2006 Jan-Feb;30(1):32-6
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  • Histopathology showed hyaline cartilage with nests of chondrocytes in the lacunae.
  • Soft-tissue chondroma is a rare, benign soft-tissue tumor.
  • [MeSH-major] Chondroma / pathology. Finger Phalanges / pathology. Soft Tissue Neoplasms / pathology. Toe Phalanges / pathology. Wrist Joint / pathology

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  • (PMID = 16377482.001).
  • [ISSN] 0899-7071
  • [Journal-full-title] Clinical imaging
  • [ISO-abbreviation] Clin Imaging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
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65. Altay M, Bayrakci K, Yildiz Y, Erekul S, Saglik Y: Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients. J Orthop Sci; 2007 Sep;12(5):415-23
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  • [Title] Secondary chondrosarcoma in cartilage bone tumors: report of 32 patients.
  • BACKGROUND: Secondary malignancies arising from benign bone tumors are rare.
  • In this study, malignant transformation rates of various histological types of benign cartilage-forming bone tumors in large series were evaluated.
  • METHODS: Between 1986 and 2004, a retrospective analysis of 627 cartilage-forming benign bone tumors revealed that 32 patients had malignant transformation.
  • RESULTS: The rate of malignant transformation for cartilage-originating tumors was 5.1% (solitary osteochondromas 4.2%, multiple osteochondromas 9.2%, solitary enchondromas 4.2%).
  • Five patients (15.6%) died of tumor recurrence or metastasis at an average of 20.6 months.
  • One patient is alive with tumor at 104 months.
  • CONCLUSIONS: Cartilage-forming benign bone tumors are rather prone to undergo malignant transformation.
  • Although malignant transformation of a benign bone tumor is a rarely encountered situation, orthopedic surgeons should be cautious while following patients with a benign bone neoplasm.
  • [MeSH-major] Bone Neoplasms / pathology. Cartilage / pathology. Chondrosarcoma / secondary. Neoplasms, Second Primary / pathology. Osteochondroma / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cell Transformation, Neoplastic / pathology. Female. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 17909925.001).
  • [ISSN] 0949-2658
  • [Journal-full-title] Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association
  • [ISO-abbreviation] J Orthop Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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66. Sassi SH, Doghri R, Kanoun ML, Maitig MB, Driss M, Mrad K, Abbes I, Esaadam H, Romdhane KB: [Desmoplastic fibroblastoma of the foot]. Rev Chir Orthop Reparatrice Appar Mot; 2008 Apr;94(2):188-92
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  • [Transliterated title] Le fibroblastome desmoplastique du pied A propos d'un cas.
  • Desmoplastic fibroblastoma is a benign, rare, slow-growing soft tissue tumor which is found in a wide anatomic distribution, predominantly in adult males.
  • The characteristic gross aspect is that of a typical cartilage-like tumor which histologically presents regular fibroblastic proliferation, often in a stellar shape within a dense collagen or myxo-collagen stroma.
  • [MeSH-major] Fibroma, Desmoplastic. Foot Diseases. Soft Tissue Neoplasms

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  • (PMID = 18420065.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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67. Ribas Mde O, Martins WD, de Sousa MH, Zanferrari FL, Lanzoni T: Osteochondroma of the mandibular condyle: literature review and report of a case. J Contemp Dent Pract; 2007;8(4):52-9
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  • BACKGROUND: While osteochondroma is the most common tumor of skeletal bones, it is relatively uncommon in the jaws occurring at the condyle or the tip of the coronoid process.
  • This benign cartilage-capped growth is usually discovered incidentally on radiographic examination or on palpation of a protruding mass in the affected area.
  • Surgical treatment was tumor resection, grafting, and reshaping of the mandibular angle and ramus.
  • SUMMARY: Condylectomy cannot be recommended as routine in all cases.37 Common surgical treatments include condylectomy and reconstruction.24 If the tumor involves only a limited area of the condylar surface, then preservation of the remaining portion of the condyle and reshaping should be done.
  • [MeSH-major] Mandibular Condyle / surgery. Mandibular Neoplasms / surgery. Oral Surgical Procedures / methods. Osteochondroma / surgery

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  • (PMID = 17486187.001).
  • [ISSN] 1526-3711
  • [Journal-full-title] The journal of contemporary dental practice
  • [ISO-abbreviation] J Contemp Dent Pract
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 49
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68. Güvenç BH, Etus V, Muezzinoglu B: Lumbar teratoma presenting intradural and extramedullary extension in a neonate. Spine J; 2006 Jan-Feb;6(1):90-3
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  • Total removal of the tumor was achieved.
  • The pathological examination showed a benign teratoma containing mature cartilage, muscle, adipose tissue, and glandular tissue.
  • CONCLUSION: Accompanying a spinal dysraphic state, the mature teratoma in our case may support the idea of a tumor actually arising from a dysraphism and growing outward to produce the mass.
  • [MeSH-major] Lumbar Vertebrae. Neoplasm Invasiveness / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Neoplasms / diagnosis. Teratoma / diagnosis
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Humans. Immunohistochemistry. Infant, Newborn. Magnetic Resonance Imaging. Neoplasm Staging. Neurosurgical Procedures / methods. Recovery of Function. Risk Assessment

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  • (PMID = 16413454.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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69. Alman BA, Wunder JS: Parathyroid hormone-related protein regulates glioma-associated oncogene transcriptional activation: lessons learned from bone development and cartilage neoplasia. Ann N Y Acad Sci; 2008 Nov;1144:36-41
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  • [Title] Parathyroid hormone-related protein regulates glioma-associated oncogene transcriptional activation: lessons learned from bone development and cartilage neoplasia.
  • By studying the interaction of the pathways in normal and neoplastic growth-plate chondrocytes (from enchondromas, a benign cartilage tumor), an unexpected direct regulation of hedgehog-mediated transcriptional activation by parathyroid hormone-related protein was uncovered.
  • [MeSH-major] Bone Development / genetics. Bone Neoplasms / metabolism. Cartilage / metabolism. Chondroma / metabolism. Chondrosarcoma / metabolism. Parathyroid Hormone-Related Protein / metabolism. Transcription Factors / metabolism. Transcriptional Activation

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  • (PMID = 19076361.001).
  • [ISSN] 1749-6632
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Hedgehog Proteins; 0 / Parathyroid Hormone-Related Protein; 0 / Transcription Factors
  • [Number-of-references] 32
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70. Hakan T, Vardar Aker F: Chondromyxoid fibroma of frontal bone: a case report and review of the literature. Turk Neurosurg; 2008 Jul;18(3):249-53
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  • Chondromyxoid fibroma is an unusual benign tumor of cartilaginous tissues that may be confused with other some malign tumors.
  • The patient underwent tumor excision with craniectomy, then acrylic cranioplasty.
  • In conclusion, chondromyxoid fibroma is a benign primary bone tumor that is located extremely rarely in the frontal bone.
  • En block surgical resection of the tumor is the cornerstone of treatment.
  • [MeSH-major] Chondroma / pathology. Fibroma / pathology. Frontal Bone / pathology. Skull Neoplasms / pathology

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  • (PMID = 18814113.001).
  • [ISSN] 1019-5149
  • [Journal-full-title] Turkish neurosurgery
  • [ISO-abbreviation] Turk Neurosurg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 22
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71. Vialle R, Feydy A, Rillardon L, Tohme-Noun C, Anract P, Colombat M, De Pinieux G, Drapé JL, Guigui P: Chondroblastoma of the lumbar spine. Report of two cases and review of the literature. J Neurosurg Spine; 2005 May;2(5):596-600
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  • Chondroblastoma is a benign cartilaginous neoplasm that generally affects the appendicular skeleton.
  • Magnetic resonance imaging allowed the authors to study the tumor's local extension.
  • [MeSH-major] Chondroblastoma / pathology. Chondroblastoma / surgery. Spinal Fusion. Spinal Neoplasms / pathology. Spinal Neoplasms / surgery
  • [MeSH-minor] Adult. Female. Humans. Low Back Pain / etiology. Lumbar Vertebrae / pathology. Lumbar Vertebrae / surgery. Magnetic Resonance Imaging. Middle Aged. Neoplasm Recurrence, Local

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  • (PMID = 15945435.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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72. Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M: Osteochondromas: review of the clinical, radiological and pathological features. In Vivo; 2008 Sep-Oct;22(5):633-46
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  • Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones.
  • This tumor takes the form of a cartilage-capped bony outgrowth on the surface of the bone.
  • [MeSH-major] Bone Neoplasms / pathology. Bone Neoplasms / radiography. Osteochondroma / pathology. Osteochondroma / radiography

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  • (PMID = 18853760.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
  • [Number-of-references] 125
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73. Chen S, Wang S, Gao J, Zhang S: [Pleuropulmonary blastoma: a clinicopathological analysis]. Zhongguo Fei Ai Za Zhi; 2010 May;13(5):550-3
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  • BACKGROUND AND OBJECTIVE: Pleuropulmonary blastoma (PPB) is a rare malignant tumor with unique clinicopathological features.
  • Histologically, these tumors included 1 case of type I PPB which showed pure cystic architecture; 2 cases were type II PPB which showed cystic and solid masses accompanied with rhabdomyoblastic differentiation and nodules of cartilage; the other 2 cases were type III PPB and characterized by absolute solid masses with anaplastic undifferentiated sarcomatous components.
  • Immunohistochemical studies showed that tumor cells were positive for Vimentin and some for Desmin and Myogenin, the nodules of cartilage were positive for S-100.
  • The tumor cells were negative for PCK, EMA and CD99.
  • This kind of tumor should be distinguished from some benign and malignant diseases such as congenital cystic adenomatoid malformation (CCAM) and embryonal rhabdomyosarcoma.
  • [MeSH-major] Lung Neoplasms / pathology. Pleural Neoplasms / pathology. Pulmonary Blastoma / pathology


74. Ito R, Fujiwara M, Takagaki K, Nagasako R: Chondrolipoma of the toe. J Dermatol; 2007 Aug;34(8):570-2
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  • Chondrolipoma is a rare benign mesenchymoma composed of mature cartilage and adipose tissue.
  • On histological examination, the tumor contained both mature fat cells and chondrocytes.
  • [MeSH-major] Foot Diseases / diagnosis. Mesenchymoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adipose Tissue / pathology. Aged. Cartilage / pathology. Humans. Magnetic Resonance Imaging. Male. S100 Proteins / analysis. Toes / pathology. Toes / radiography

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  • (PMID = 17683390.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / S100 Proteins
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75. Jundt G, Baumhoer D: [Cartilage tumors of the skeleton]. Pathologe; 2008 Nov;29 Suppl 2:223-31
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  • [Title] [Cartilage tumors of the skeleton].
  • Although the spectrum of benign and malignant cartilaginous bone tumors is extremely wide, a distinct diagnosis, even from small biopsy specimens, is almost always possible if radiological findings, age, clinical data, and localization within the skeleton as well as within the bone are considered.
  • With limitations, this also holds true for distinguishing enchondromas from low-grade chondrosarcomas; however, extensive experience in multidisciplinary bone tumor diagnosis is required.
  • [MeSH-major] Bone Neoplasms / pathology. Chondroblastoma / pathology. Chondroma / pathology. Chondrosarcoma / pathology. Osteochondroma / pathology

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  • [Cites] Ann R Coll Surg Engl. 2003 Jul;85(4):272-6 [12855033.001]
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  • (PMID = 18820927.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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76. Karkuzhali P, Chithralekha S, Muthuvel E, Daniel RB: Chondromyxoid fibroma of the parietal bone. Neuropathology; 2005 Mar;25(1):84-8
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  • Chondromyxoid fibroma is a benign cartilaginous neoplasm, which can be easily mistaken for chondrosarcoma, especially in small biopsies.
  • [MeSH-major] Chondroblastoma / pathology. Parietal Bone / pathology. Skull Neoplasms / pathology

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  • (PMID = 15822822.001).
  • [ISSN] 0919-6544
  • [Journal-full-title] Neuropathology : official journal of the Japanese Society of Neuropathology
  • [ISO-abbreviation] Neuropathology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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77. Sheahan P, Hafidh M, Toner M, Timon C: Unexpected findings in neck dissection for squamous cell carcinoma: incidence and implications. Head Neck; 2005 Jan;27(1):28-35
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  • These included metastatic papillary thyroid carcinoma, leukemia, lymphoma, Warthin's tumor, and tuberculosis.
  • Two of three patients with benign-appearing thyroid tissue within lymph nodes received no further treatment, and both remained well beyond 6 years.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Head and Neck Neoplasms / surgery. Neck Dissection
  • [MeSH-minor] Adenolymphoma / pathology. Adenolymphoma / therapy. Aged. Aged, 80 and over. Carcinoma, Papillary / pathology. Carcinoma, Papillary / secondary. Carcinoma, Papillary / surgery. Cricoid Cartilage / pathology. Female. Humans. Leukemia, Lymphocytic, Chronic, B-Cell / pathology. Leukemia, Lymphocytic, Chronic, B-Cell / therapy. Lymphatic Metastasis. Lymphoma, B-Cell / pathology. Lymphoma, B-Cell / therapy. Male. Middle Aged. Retrospective Studies. Thyroid Neoplasms / pathology. Thyroid Neoplasms / secondary. Thyroid Neoplasms / surgery. Thyroidectomy. Tuberculosis, Lymph Node / drug therapy. Tuberculosis, Lymph Node / pathology


78. Hill DA, Jarzembowski JA, Priest JR, Williams G, Schoettler P, Dehner LP: Type I pleuropulmonary blastoma: pathology and biology study of 51 cases from the international pleuropulmonary blastoma registry. Am J Surg Pathol; 2008 Feb;32(2):282-95
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  • Pleuropulmonary blastoma (PPB) is a malignant neoplasm of the lung that presents in early childhood.
  • Type I PPB is a delicate multilocular cyst with variable numbers of primitive mesenchymal cells beneath a benign epithelial surface.
  • Rhabdomyoblasts and cartilage nodules are seen in 49% and 40% of cases, respectively.
  • Early tumors have a subtle transition between normal developing lung and tumor, showing bland interstitial mesenchymal cells uniformly expanding the alveolar septa.
  • This phenomenon may explain the variable and sometimes sparse tumor cellularity seen in some type I PPBs.
  • Factors that control the balance between progression and regression may be important in predicting tumor behavior and determining which patients will benefit from adjuvant chemotherapy.
  • In the meantime, recognition of this lesion as a neoplasm with malignant potential rather than a developmental cystic malformation is vital so the child can receive complete excision and appropriate follow-up care.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / pathology. Lung Neoplasms / pathology. Pleural Neoplasms / pathology. Pulmonary Blastoma / pathology


79. Boulytcheva IV, Kushlinskii NE, Dvorova EK, Kazachok IV, Makhson AN: Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitor-1 in cartilage-forming osteal tumors. Bull Exp Biol Med; 2010 Sep;149(3):341-6
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  • [Title] Expression of matrix metalloproteinases 1, 2, 9 and their tissue inhibitor-1 in cartilage-forming osteal tumors.
  • The expression of MMP-1, -2, -9 and TIMP-1 was studied in 10 benign cartilage-forming osteal tumors (5 osteochondromas and 5 chondromas) and 39 chondrosarcomas (14 central, 4 periosteal, 7 dedifferentiated, and 14 secondary tumors).
  • No expression of MMP and TIMP-1 was detected in benign cartilage-forming osteal tumors.
  • The expression of MMP-1 was not associated with patient gender, maximum size and degree of differentiation of the tumor, but was linked with age.
  • The expression of MMP-1 in the tumor was associated with unfavorable course of the disease.
  • [MeSH-minor] Age Factors. Cartilage / metabolism. Female. Humans. Immunohistochemistry. Male. Prognosis. Sex Factors

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  • (PMID = 21246097.001).
  • [ISSN] 1573-8221
  • [Journal-full-title] Bulletin of experimental biology and medicine
  • [ISO-abbreviation] Bull. Exp. Biol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tissue Inhibitor of Metalloproteinase-1; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; EC 3.4.24.7 / Matrix Metalloproteinase 1
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80. Sepah YJ, Umer M, Minhas K, Hafeez K: Chondroblastoma of the cuboid with an associated aneurysmal bone cyst: a case report. J Med Case Rep; 2007;1:135
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  • We report the case of a young adult who presented with a painful foot due to chondroblastoma associated with an aneurismal bone cyst.Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for approximately 1% of all bone tumors and characteristically arises in the epiphysis of a long bone, particularly the humerus, tibia, and femur.

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  • (PMID = 17999776.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2194702
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81. Yamaguchi R, Tanaka M, Yokoyama T, Nonaka Y, Kojima K, Terasaki H, Yamaguchi M, Fukunaga M, Toh U, Nakashima O, Kage M, Yano H: Clinicocytopathology of breast cancers with a ring-like appearance on ultrasonography and/or magnetic resonance imaging. Pathol Int; 2010 Jan;60(1):22-6
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  • On breast cancer imaging some cancers have an anechoic or high-echoic zone in the tumor on ultrasonography and ring-shaped enhancement on contrast-enhanced magnetic resonance imaging (MRI) with high intensity in the central area of the tumor on T2-weighted imaging, necessitating their differentiation from benign disease.
  • Histologically the cancer cells of these lesions showing a ring-like appearance were located in the periphery of the tumor, with a central hypocellular zone.
  • The percentage ratio of the cancer-zone width to the tumor diameter was 26.4 +/- 7.8 and 8.0 +/- 3.2 (mean +/- SD), respectively (P= 0.003).
  • In two MPC and three CAC, cartilage matrix and amorphous material, respectively, were observed in the background.
  • [MeSH-major] Breast Neoplasms / diagnosis. Carcinoma, Acinar Cell / diagnosis

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  • [ErratumIn] Pathol Int. 2010 Apr;60(4):336. Nonaka, Hideyuki [corrected to Nonaka, Yasuhide]
  • (PMID = 20055948.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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82. Meyer MA, Becker JM, Quinones W: Endobronchial granular cell tumor: a case report. J Radiol Case Rep; 2010;4(8):29-35
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  • [Title] Endobronchial granular cell tumor: a case report.
  • Granular cell tumors (GCTs) are benign neoplasms that are most commonly found in the head and neck region.
  • We present a case of endobronchial granular cell tumor presenting as hemoptysis in a 22-year-old African American female.
  • Patient subsequently underwent a right upper and middle lobectomy, and upon histologic analysis was found to have GCT with borders impinging upon cartilage and adjacent peribronchial lymph nodes.

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  • (PMID = 22470750.001).
  • [ISSN] 1943-0922
  • [Journal-full-title] Journal of radiology case reports
  • [ISO-abbreviation] J Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3303395
  • [Keywords] NOTNLM ; Granular cell tumor / endobronchial
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83. Bulycheva IV, Semenov LA, Makhson AN, Zhukov AG: [Chondroblastoma]. Arkh Patol; 2007 May-Jun;69(3):53-6
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  • Chondroblastom, benign cartilage tissue neoplasm, accounts for 1% of all bone tumors.
  • Cartilaginous portions of chondroblastoma form lobular structures.
  • The tumor always comprises single-to-multiple multinucleate giant cells.
  • [MeSH-major] Bone Neoplasms / radiography. Bone Neoplasms / therapy. Chondroblastoma / radiography. Chondroblastoma / therapy

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  • (PMID = 17722601.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Lectures
  • [Publication-country] Russia (Federation)
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84. Rubin G, Wolovelsky A, Rinott M, Rozen N: Osteoid osteoma of the hamate: an unusual cause of ulnar-sided wrist pain. Orthopedics; 2010 Jul;33(7):513
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  • Osteoid osteoma is a benign skeletal neoplasm of unknown etiology that is composed of osteoid and woven bone.
  • Its incidence is 11% of benign tumors and 3% of all primary bone tumors, with 6% to 13% of all cases occurring in the hand.
  • Osteoid osteoma of the hamate can produce ulnar-sided wrist pain in the dorsal or volar aspect of the wrist, depending on the location of the tumor in the bone.
  • Occasionally it destroys the articular cartilage by erosion or penetration.
  • A tumor located in the hook will produce volar pain.
  • [MeSH-major] Arthralgia / diagnosis. Bone Neoplasms / pathology. Hamate Bone / pathology. Osteoma, Osteoid / pathology. Ulna / pathology

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20608627.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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85. Romeo S, Duim RA, Bridge JA, Mertens F, de Jong D, Dal Cin P, Wijers-Koster PM, Debiec-Rychter M, Sciot R, Rosenberg AE, Szuhai K, Hogendoorn PC: Heterogeneous and complex rearrangements of chromosome arm 6q in chondromyxoid fibroma: delineation of breakpoints and analysis of candidate target genes. Am J Pathol; 2010 Sep;177(3):1365-76
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  • Chondromyxoid fibroma (CMF) is an uncommon benign cartilaginous tumor of bone usually occurring during the second decade of life.
  • Two known tumor suppressor genes map to the latter region: PLAGL1 and UTRN.
  • [MeSH-major] Bone Neoplasms / genetics. Chromosome Aberrations. Chromosomes, Human, Pair 6. Fibroma / genetics
  • [MeSH-minor] Cartilage / metabolism. Cartilage / pathology. Cytogenetic Analysis. Humans. Immunohistochemistry. In Situ Hybridization. Polymerase Chain Reaction. Repressor Proteins / genetics. Repressor Proteins / metabolism. Tumor Suppressor Proteins / genetics. Tumor Suppressor Proteins / metabolism. Utrophin / genetics. Utrophin / metabolism

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  • (PMID = 20696777.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / BCLAF1 protein, human; 0 / Repressor Proteins; 0 / Tumor Suppressor Proteins; 0 / Utrophin
  • [Other-IDs] NLM/ PMC2928969
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86. Kiralj A, Ilić M, Markov B, Dedić S, Pejaković B, Nalić B: [Chondroma of the skull base and maxilla]. Med Pregl; 2007 Nov-Dec;60(11-12):649-51
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  • INTRODUCTION: Chondromas are uncommon benign tumors of cartilaginous origin.
  • A chondroma is a painless, slow growing tumor causing destruction and exfoliation of teeth.
  • On a radiograph, the tumor appears as a cyst-like radiolucent lesion, while some are sclerotic.
  • DISCUSSION AND CONCLUSION: Chondromyxoid fibroma (CMF) is a rare, benign cartilaginous tumor that often occurs in the metaphyses of proximal tibia, proximal and distal femur and small bones of the foot.
  • The differential diagnosis is wide and includes simple or aneyrismal bone cyst, giant cell tumor, nonossifying fibroma, fibrous dysplasia, enchondroma, chondroblastoma, eosinophilic granuloma and fibrous cortical defect.
  • In the diagnosis of an intracranial chondrocytic tumor, it is important to distinguish it from enchondroma and chondrosarcoma.
  • [MeSH-major] Chondroma. Maxillary Neoplasms. Skull Base Neoplasms

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  • (PMID = 18666612.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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87. Villanueva J, González A, Cornejo M, Núñez C, Encina S: Osteochondroma of the coronoid process. Med Oral Patol Oral Cir Bucal; 2006 May;11(3):E289-91
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  • Osteochondroma is the most common benign neoplasia of the skeleton.
  • In panoramic radiographs was evident a coronoid tumor localized in the union of zigomatic arch and bone.
  • Histopatological examinations revealed normal trabecular bone covered with hyaline cartilage.
  • [MeSH-major] Mandibular Neoplasms. Osteochondroma

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  • (PMID = 16648770.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 13
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88. Hwang HS, Lee WJ, Lim HK, Chun HK, Ahn GH: Chondrolipoma in the pelvic cavity: a case report. Korean J Radiol; 2008 Nov-Dec;9(6):563-7
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  • A chondrolipoma is an extremely rare form of a benign mesenchymal tumor containing mature cartilage and fatty tissue.
  • [MeSH-major] Chondroma / diagnosis. Lipoma / diagnosis. Mesenchymoma / diagnosis. Pelvic Neoplasms / diagnosis

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  • (PMID = 19039275.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627234
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89. Yalniz E, Alicioglu B, Yalcin O, Yilmaz B: Non specific magnetic resonance features of chondromyxoid fibroma of the iliac bone. J BUON; 2007 Jul-Sep;12(3):407-9
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  • Chondromyxoid fibroma is a benign cartilaginous neoplasm.
  • The tumor is rare, perhaps the rarest of all bone tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Chondroma / diagnosis. Fibroma / diagnosis. Ilium. Magnetic Resonance Imaging

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  • (PMID = 17918298.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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90. McLoughlin GS, Sciubba DM, Wolinsky JP: Chondroma/Chondrosarcoma of the spine. Neurosurg Clin N Am; 2008 Jan;19(1):57-63
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondromas and chondrosarcomas are cartilage-forming tumors that occur rarely in the spine.
  • These neoplasms exist on opposite ends of the pathologic spectrum, ranging from the benign chondroma to the malignant, high-grade chondrosarcoma.
  • Unlike other sarcomas, a patient's long-term prognosis is influenced by the grade of the tumor.
  • Hypofractionated stereotactic radiation therapy may slow tumor progression, although the long-term effect of this modality is unknown.
  • [MeSH-major] Chondroma / pathology. Chondroma / surgery. Chondrosarcoma / pathology. Chondrosarcoma / surgery. Spinal Neoplasms / pathology. Spinal Neoplasms / surgery
  • [MeSH-minor] Humans. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / prevention & control. Neurosurgical Procedures / methods. Prognosis. Radiosurgery / methods. Radiotherapy / methods. Spine / pathology. Spine / surgery

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  • (PMID = 18156048.001).
  • [ISSN] 1558-1349
  • [Journal-full-title] Neurosurgery clinics of North America
  • [ISO-abbreviation] Neurosurg. Clin. N. Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 49
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91. Choi YD, Kim SS, Lee JS, Nam JH, Choi C, Na KJ, Lee JH: Abundant cartilage formation of congenital pulmonary airway malformation--a case report. Pathol Res Pract; 2009;205(7):494-7
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  • [Title] Abundant cartilage formation of congenital pulmonary airway malformation--a case report.
  • We report an unusual case of type 1 CPAM with abundant cartilage in a 5-year-old boy.
  • On chest radiography, a left lung mass was detected incidentally, and tumor resection was performed under the impression of a benign tumor.
  • The pathological examination of the mass revealed abundant cartilage in the walls of malformed bronchioles with partially cystic dilatation.
  • We think that this case represents a cartilaginous variant of CPAM.
  • The cartilaginous variant of CPAM should be differentiated pathologically from other pulmonary neoplasms containing abundant cartilage, such as chondroid hamartoma.
  • [MeSH-major] Bronchioles / abnormalities. Cartilage / pathology. Incidental Findings. Lung Neoplasms / diagnosis. Respiratory System Abnormalities / pathology

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  • (PMID = 19231095.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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92. Mohler DG, Chiu R, McCall DA, Avedian RS: Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function. Clin Orthop Relat Res; 2010 Oct;468(10):2765-73
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  • [Title] Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function.
  • Grade 1 chondrosarcomas have little or no metastatic potential and are often difficult to distinguish from painful benign enchondromas.
  • Patients were followed a minimum of 18 months (average, 47.2. months; range, 18-134 months) for evidence of recurrence and for assessment of Musculoskeletal Tumor Society (MSTS) functional score.
  • RESULTS: Two of the 46 patients had recurrences in the original tumor site (4.3% recurrence rate), which subsequently were removed by wide excision, and both patients were confirmed to be disease-free 36 and 30 months, respectively, after the second surgery.
  • [MeSH-major] Bone Neoplasms / surgery. Chondroma / surgery. Chondrosarcoma / surgery. Cryosurgery. Curettage
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Recovery of Function. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 20574801.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3049634
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93. Storlazzi CT, Wozniak A, Panagopoulos I, Sciot R, Mandahl N, Mertens F, Debiec-Rychter M: Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22). Int J Cancer; 2006 Apr 15;118(8):1972-6
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  • [Title] Rearrangement of the COL12A1 and COL4A5 genes in subungual exostosis: molecular cytogenetic delineation of the tumor-specific translocation t(X;6)(q13-14;q22).
  • Subungual exostosis is a benign bone- and cartilage-producing tumor occurring in the hands and feet of children and young adults.
  • The recent identification of a recurrent chromosomal translocation t(X;6)(q24-q26;q15-21) in short-term-cultured tumor cells strongly suggests that subungual exostosis is a neoplastic lesion caused by rearrangement of genes in the two breakpoints.

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16284948.001).
  • [ISSN] 0020-7136
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / COL4A5 protein, human; 0 / Collagen Type IV; 0 / Collagen Type XI
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94. Carrera JE, Castillo PA, Molina OM: [Lumbar osteochondroma and radicular compression. A case report]. Acta Ortop Mex; 2007 Sep-Oct;21(5):261-6
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  • [Transliterated title] Osteocondroma de lámina lumbar y compresión radicular. Reporte de un caso.
  • Most cartilage forming tumors are benign and rarely affect the spinal canal, their principal location is in humerus metaphysis, femur and tibia.
  • They represent 2% of all tumors and 2.6% of the benign tumors of the spine, usually located at the cervical spine.
  • It is speculated that the secondary ossification center may be aberrant cartilaginous tissue that causes the formation of osteochondroma.
  • It was performed: total removal of the tumor effectively and symptoms disappeared.
  • [MeSH-major] Lumbar Vertebrae / surgery. Nerve Compression Syndromes / etiology. Osteochondroma / complications. Spinal Cord Compression / etiology. Spinal Neoplasms / complications. Spinal Nerve Roots

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  • (PMID = 18159915.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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