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Items 1 to 33 of about 33
1. Samaila MO: Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med; 2008 Mar;7(1):6-10
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  • [Title] Adnexal skin tumors in Zaria, Nigeria.
  • BACKGROUND: Adnexal skin tumors share many features in common and differentiate along one line.
  • METHOD: A 16-year retrospective analysis of all adnexal skin tumors seen in a large University Teaching Hospital in Nigeria from January 1991- December 2006.
  • Only two cases had a clinical diagnosis of adnexal tumor.
  • Forty-six lesions (88.5%) were benign and six (11.5%) malignant.
  • CONCLUSION: Adnexal skin tumors have distinct histological patterns which differentiates them from other cutaneous tumors.
  • They are commonly distributed in the head, neck and trunk.
  • [MeSH-major] Carcinoma, Skin Appendage / classification. Neoplasms, Adnexal and Skin Appendage / classification

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  • (PMID = 18702242.001).
  • [ISSN] 1596-3519
  • [Journal-full-title] Annals of African medicine
  • [ISO-abbreviation] Ann Afr Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nigeria
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2. Kong YY, Kong JC, Shi DR, Lu HF, Zhu XZ, Wang J, Chen ZW: Cutaneous rosai-dorfman disease: a clinical and histopathologic study of 25 cases in China. Am J Surg Pathol; 2007 Mar;31(3):341-50
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  • Cutaneous Rosai-Dorfman disease (CRDD) is a rare proliferative disorder of histiocytes with unknown etiology, broadly different from systemic Rosai-Dorfman disease.
  • Clinically, 39 skin lesions in 25 patients were divided into 3 main types: papulonodular type (79.5%), indurated plaque type (12.8%), and tumor type (7.7%).
  • Extremities were the most frequently involved, followed by trunk and face.
  • Owing to its favorable outcome, CRDD should be differentiated from a variety of benign and malignant lesions.
  • Recognition of its wide clinical spectrum and histologic features combined with S-100 protein stain can help to establish the correct diagnosis.
  • [MeSH-major] Histiocytosis, Sinus / pathology. Skin Diseases / pathology

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  • (PMID = 17325475.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / S100 Proteins
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3. Na JI, Cho KH, Kim YG, Park KC: Angioblastoma showing aggravation after treatment with long-pulsed Nd:YAG laser (1064 nm). Pediatr Dermatol; 2007 Jul-Aug;24(4):397-400
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  • Angioblastoma usually develops in infancy or early childhood on the neck or upper trunk.
  • It is known to be slowly progressive and benign in nature, but treatment guidelines have not yet been established.
  • However, unexpectedly, the tumor was rapidly aggravated.
  • [MeSH-major] Hemangioblastoma / pathology. Hemangioblastoma / radiotherapy. Lasers / adverse effects. Skin Neoplasms / pathology. Skin Neoplasms / radiotherapy

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  • (PMID = 17845165.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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4. Vandergriff TW, Reed JA, Orengo IF: An unusual presentation of atypical fibroxanthoma. Dermatol Online J; 2008;14(1):6
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  • Atypical fibroxanthoma (AFX) is a rare cutaneous spindle-cell neoplasm.
  • The tumor occurs most commonly in sun-damaged skin of the head and neck in elderly patients.
  • A small subset of patients (approximately one in five cases) is middle-aged and presents with AFX of the trunk or extremities in areas without evidence of actinic damage.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 18319023.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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5. Kutzner H, Mentzel T, Palmedo G, Hantschke M, Rütten A, Paredes BE, Schärer L, Guillen CS, Requena L: Plaque-like CD34-positive dermal fibroma ("medallion-like dermal dendrocyte hamartoma"): clinicopathologic, immunohistochemical, and molecular analysis of 5 cases emphasizing its distinction from superficial, plaque-like dermatofibrosarcoma protuberans. Am J Surg Pathol; 2010 Feb;34(2):190-201
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  • We analyzed the clinical, histomorphologic, and molecular criteria of 5 DH and 7 DFSP to delineate diagnostically relevant differences between incipient dermal DFSP and its benign look-alike, DH.
  • Both PDF/DH and DFSP presented as slightly pigmented and indurated plaques on neck, trunk, and extremities.
  • [MeSH-major] Antigens, CD34 / metabolism. Dermatofibrosarcoma / diagnosis. Fibroma / diagnosis. Hamartoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Child. Diagnosis, Differential. Disease-Free Survival. Female. Gene Rearrangement. Humans. In Situ Hybridization, Fluorescence. Male. Middle Aged. Oncogene Proteins, Fusion / genetics. Oncogene Proteins, Fusion / metabolism. Reverse Transcriptase Polymerase Chain Reaction. Sequence Analysis, DNA


6. García-Gutiérrez M, Toussaint-Caire S, González-Sánchez P, Ortiz-Hidalgo C: Multiple desmoplastic cellular neurothekeomas localized to the face of a 16-year-old boy. Am J Dermatopathol; 2010 Dec;32(8):841-5
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  • Cellular neurothekeomas are relative uncommon benign dermal tumors of uncertain histogenesis.
  • Most commonly they arise as a solitary papule or nodule on the head and neck or upper trunk of young adults with a slight female predominance.
  • Immunohistochemical staining showed that the cells of interest expressed S100A6, vimentin, CD63 (NKI/C3), PGP 9.5, and factor XIIIa and were negative for CD68, glial fibrillary acid protein (GFAP), S-100, HMB-45, epithelial membrane antigen, actin, and CD57 consistent with a diagnosis of multiple desmoplastic cellular neurothekeomas.
  • [MeSH-major] Facial Neoplasms / pathology. Neurothekeoma / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biomarkers, Tumor / analysis. Biopsy. Humans. Immunohistochemistry. Male

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  • (PMID = 21137111.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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7. Nishi SP, Brey NV, Sanchez RL: Dermal nodular fasciitis: three case reports of the head and neck and literature review. J Cutan Pathol; 2006 May;33(5):378-82
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  • Nodular fasciitis is a benign reactive myofibroblastic proliferative process of unknown etiology.
  • The condition is self-limited, and proper diagnosis is essential to avoid unnecessary aggressive treatment.
  • Diagnosis is often a challenge because it may be confused with a malignant tumor due to its aggressive clinical behavior and histological features.
  • Immunohistochemical staining can be a useful tool to aid in the diagnosis.
  • Although most commonly located on the extremities and then the trunk, it is estimated that the head and neck region represents only 10 to 20%.
  • [MeSH-major] Fasciitis / pathology. Skin Diseases / pathology
  • [MeSH-minor] Adolescent. Adult. Diagnosis, Differential. Female. Head and Neck Neoplasms / pathology. Humans. Immunohistochemistry. Male. Skin Neoplasms / pathology

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  • (PMID = 16640547.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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8. Billings SD, Folpe AL: Diagnostically challenging spindle cell lipomas: a report of 34 "low-fat" and "fat-free" variants. Am J Dermatopathol; 2007 Oct;29(5):437-42
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  • Spindle cell lipomas (SCL) classically occur as subcutaneous masses in the upper trunk/neck of older men and are composed of mature fat, CD34-positive spindled cells, ropey collagen, myxoid matrix, and blood vessels.
  • A review of over 300 consultation cases diagnosed as SCL revealed 34 cases in which fat was noted to be present in <5% of the tumor (n = 30) or absent (n = 4).
  • In the majority, referring pathologists considered benign diagnoses, usually benign nerve sheath tumors, but in four cases low-grade sarcoma was considered.
  • A high index of suspicion based on clinical context and identification of other typical features of SCL are key features to the diagnosis of low-fat and fat-free SCL.
  • [MeSH-major] Adipocytes / pathology. Lipoma / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 17890910.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34
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9. Cohen PR, Martinelli PT, Schulze KE, Nelson BR: The cuticular purse string suture: a modified purse string suture for the partial closure of round postoperative wounds. Int J Dermatol; 2007 Jul;46(7):746-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: The purse string suture can be used to provide primary closure for small skin defects or as a partial closure for larger round wounds.
  • The size of the defect is reduced secondary to the tension placed on the suture, which uniformly advances the skin from the entire periphery of the wound.
  • RESULTS: Postoperative wounds were created following Mohs' micrographic excision of nonmelanoma skin cancer (basal cell carcinoma, 44; squamous cell carcinoma, 25), wide local excision of melanoma (29), or conservative excision of benign cutaneous neoplasms (two).
  • The incidence of purse string suture for partial closure of each tumor was 4.1% for basal cell carcinoma, 7.3% for squamous cell carcinoma, and 46.3% for melanoma.
  • The tumors were equally distributed on the trunk, head and neck, and extremities; however, purse string closures for basal cell carcinomas were more frequent on the trunk, head, and neck, relative to squamous cell carcinomas and melanomas, which were more common on the extremities.
  • CONCLUSION: The cuticular purse string suture is a rapid and simple procedure that provides complete or partial closure of round skin defects and excellent long-term cosmetic and functional results.
  • The purse string suture is also useful following nonmelanoma skin cancer removal in patients who insist on maintaining an active lifestyle in the immediate postoperative period, who are receiving one or more systemic anticoagulant and/or antiplatelet agents, and who have large surgical wounds that would require either a skin graft or a local cutaneous flap in order to close the postoperative defect.
  • [MeSH-major] Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Melanoma / surgery. Skin Neoplasms / surgery. Suture Techniques

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  • (PMID = 17614809.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Tanaka H, Yamazaki N, Kawabe M, Watanabe H, Nakade M: [Ganglioneuroma derived from inferior trunk of the brachial plexus and first intercostal nerve]. Kyobu Geka; 2009 Aug;62(9):799-801
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  • [Title] [Ganglioneuroma derived from inferior trunk of the brachial plexus and first intercostal nerve].
  • A 62-years-old Japanese male, who had mediastinal tumor at the left thoracic inlet, was admitted to our hospital to receive surgical treatment.
  • The tumor behind the left subclavian artery was guessed to be neurogenic benign tumor, though the involvement of the brachial plexus was unclear.
  • We approached the tumor by means of left hemi-collar skin incision, resulting in performing safe operation with directly looking at the tumor that communicated with 1st intercostal nerve and inferior trunk of the left brachial plexus.
  • Pathological diagnosis of the resected tumor was ganglioneuroma.
  • Cervical approach by means of hemi-collar skin incision is thought to be available for surgical treatment of tumors at the thoracic inlet because of easy accessibility and less invasiveness than other approach with dividing bones, such as clavicle, sternum, or ribs.

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  • (PMID = 19670782.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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11. Breiting L, Christensen L, Dahlstrøm K, Breiting V, Winther JF: Primary mucinous carcinoma of the skin: a population-based study. Int J Dermatol; 2008 Mar;47(3):242-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary mucinous carcinoma of the skin: a population-based study.
  • BACKGROUND: Primary mucinous carcinoma of the skin (PMCS) is a rare malignant tumor deriving from the sweat glands.
  • It is typically located on the head and is often mistaken for a metastasis from a more common primary tumor of the breast or gastrointestinal tract.
  • Seven cases were found on the scalp or neck, five on the eyelids, two on the face, and one on the trunk.
  • CONCLUSION: PMCS is a rare, slow-growing tumor which rarely metastasizes and is associated with low mortality.
  • However, the precise number may be higher, since PMCS is an indolent tumor, which may be mistaken for a benign tumor and thus not always examined histologically.
  • [MeSH-major] Adenocarcinoma, Mucinous / epidemiology. Skin Neoplasms / epidemiology

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  • (PMID = 18289323.001).
  • [ISSN] 1365-4632
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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12. Repertinger S, Wang J, Adickes E, Sarma DP: Melanoma in-situ arising in seborrheic keratosis: a case report. Cases J; 2008;1(1):263
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  • BACKGROUND: Seborrheic keratosis is a very common benign skin tumor in man.
  • Melanoma is rare but is the most dreaded of all malignant skin tumors.
  • CASE PRESENTATION: An-86-year-old male with a history of multiple actinic keratoses and seborrheic keratoses of the head and trunk presented with a mid-back skin lesion.

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  • [Cites] Australas J Dermatol. 2006 May;47(2):109-13 [16637806.001]
  • [Cites] J Am Acad Dermatol. 2000 May;42(5 Pt 1):831-3 [10775864.001]
  • [Cites] Dermatol Surg. 2004 Apr;30(4 Pt 1):559-61 [15056152.001]
  • [Cites] Am J Dermatopathol. 1996 Jun;18(3):278-82 [8806962.001]
  • (PMID = 18947402.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2577645
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13. Abbasi NR, Brownell I, Fangman W: Familial multiple angiolipomatosis. Dermatol Online J; 2007;13(1):3
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  • An 80-year-old man presented with a 50-year history of asymptomatic, subcutaneous masses on the arms, trunk, and legs.
  • Histopathologic examination showed a benign angiolipoma; the same diagnosis has been made on several previous biopsy specimens.
  • This patient's history and physical examination support the diagnosis of familial angiolipomatosis, which is a benign, autosomal-dominant condition that may be regarded as a subtype of familial multiple lipomatosis (FML) or as a distinct entity.
  • Management of this condition may include liposuction or surgery to reduce the tumor burden.
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male. Severity of Illness Index. Skin / pathology

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  • (PMID = 17511936.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Mentzel T, Dei Tos AP, Sapi Z, Kutzner H: Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases. Am J Surg Pathol; 2006 Jan;30(1):104-13
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  • [Title] Myopericytoma of skin and soft tissues: clinicopathologic and immunohistochemical study of 54 cases.
  • Perivascular neoplasms comprise traditionally glomus tumor and hemangiopericytoma (HPC).
  • Whereas glomus tumor represents a well-defined entity, the existence of HPC as a separate entity has been questioned because a number of neoplasms of different lines of differentiation are characterized by a HPC-like vascular growth pattern.
  • A large series of myopericytoma of skin and soft tissues has been analyzed to further characterize the clinicopathologic spectrum of this entity.
  • Fifty-four cases of myopericytoma of skin and soft tissues were retrieved and the histology reviewed.
  • The lower extremities were most commonly affected (26 cases) followed by the upper extremities (16 cases), the head and neck region (4 cases), and the trunk (2 cases); exact location was unknown in 5 cases.
  • Histologically, in all cases, numerous thin-walled vessels and a concentric, perivascular arrangement of ovoid, plump spindled to round myoid tumor cells was seen.
  • Despite overlapping morphologic features to angioleiomyoma and myofibroma, myopericytoma represents a distinct perivascular, myoid neoplasm of skin and soft tissues, characterized by a broad morphologic spectrum of concentrically, perivascularly growing myoid tumor cells that stain positively for ASMA and often for h-caldesmon, whereas desmin is usually negative.
  • Most cases of myopericytoma behave in a benign fashion, but local recurrences and rarely metastases may occur in atypical and malignant neoplasms.
  • [MeSH-major] Biomarkers, Tumor / analysis. Neoplasms, Vascular Tissue / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Angiomyoma / pathology. Diagnosis, Differential. Female. Glomus Tumor / pathology. Hemangiopericytoma / metabolism. Hemangiopericytoma / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Myofibroma / pathology

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  • (PMID = 16330949.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Hoekzema R, Zonneveld IM, van der Wal AC: Type 2 segmental glomangiomas. Dermatol Online J; 2010;16(1):8
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  • Glomangiomas of the skin, currently named glomuvenous malformations (GVMs), are benign vascular lesions composed of thin-walled distorted blood vessels, surrounded by variable rows of glomus cells.
  • In this report we describe a 39-year-old man who developed unilateral segmental GVMs on his trunk in early childhood, with the histological features of glomangiomas.
  • As several satellite lesions emerged at distant skin sites later in life, our case probably represents type 2 segmental GVMs, caused by localized loss of heterozygosity in an individual carrying a heterozygous germline mutation in the glomulin gene.
  • [MeSH-major] Adaptor Proteins, Signal Transducing / genetics. Glomus Tumor / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology

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  • (PMID = 20137750.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / GLMN protein, human
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16. Gerber PA, Schulte KW, Ruzicka T, Bruch-Gerharz D: Eccrine porocarcinoma of the head: an important differential diagnosis in the elderly patient. Dermatology; 2008;216(3):229-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Eccrine porocarcinoma of the head: an important differential diagnosis in the elderly patient.
  • BACKGROUND: Eccrine porocarcinoma is a rare malignant tumor of the sweat gland, characterized by a broad spectrum of clinicopathologic presentations.
  • Surprisingly, unlike its benign counterpart eccrine poroma, eccrine porocarcinoma is seldom found in areas with a high density of eccrine sweat glands, like the palms or soles.
  • Instead, eccrine porocarcinoma frequently occurs on the lower extremities, trunk and abdomen, but also on the head, resembling various other skin tumors, as illustrated in the patients described herein.
  • All patients were initially diagnosed as having epidermal or melanocytic skin tumors.
  • Porocarcinomas are commonly overlooked, or misinterpreted as squamous or basal cell carcinomas as well as other common malignant and even benign skin tumors.
  • Knowledge of the clinical pattern and histologic findings, therefore, is crucial for an early therapeutic intervention, which can reduce the risk of tumor recurrence and serious complications.
  • [MeSH-major] Carcinoma, Skin Appendage / diagnosis. Eccrine Glands / pathology. Head and Neck Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Immunohistochemistry. Male. Middle Aged. Prognosis. Skin Neoplasms / diagnosis

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  • (PMID = 18182815.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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17. Chen CC, Chang YT, Liu HN: Clinical and histological characteristics of poroid neoplasms: a study of 25 cases in Taiwan. Int J Dermatol; 2006 Jun;45(6):722-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Eccrine poroma (EP) are relatively common benign eccrine neoplasms.
  • Other poroid neoplasms (PNs), namely hidroacanthoma simplex (HS), dermal duct tumor (DDT), and poroid hidradenoma (PH), are seldom reported.
  • Most EPs were located on hair-bearing regions of the limbs (37.5%) and trunk (25%), instead of soles (18.8%) and palms (6.3%).
  • Histopathologically, it is not justified to exclude PN diagnosis by noticing horn cysts.
  • [MeSH-major] Skin Neoplasms / pathology. Sweat Gland Diseases / pathology

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  • (PMID = 16796636.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Miettinen M, Fetsch JF: Reticulohistiocytoma (solitary epithelioid histiocytoma): a clinicopathologic and immunohistochemical study of 44 cases. Am J Surg Pathol; 2006 Apr;30(4):521-8
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  • Reticulohistiocytoma and multicentric reticulohistiocytosis are designations for uncommon, incompletely characterized histiocytic proliferations of the skin or soft tissues.
  • All patients had a superficial, circumscribed, mildly elevated, solitary lesion (size range, 1.5-11 mm; median, 4 mm), located in the trunk wall (n = 16), lower extremity (n = 12), head and neck (n = 8, including 2 in the oral cavity), upper extremity (n = 6), penis (n = 1), and an unspecified site (n = 1).
  • SEH is a benign, probably reactive, histiocytic proliferation of unknown etiology.
  • [MeSH-major] Epithelioid Cells / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Biomarkers, Tumor / metabolism. Child. Child, Preschool. Diagnosis, Differential. Female. Histiocytoma, Malignant Fibrous / diagnosis. Histiocytosis, Sinus / diagnosis. Humans. Male. Middle Aged. Sarcoma / diagnosis. Sex Distribution. Xanthogranuloma, Juvenile / diagnosis

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  • (PMID = 16625100.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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19. Wagamon K, Somach SC, Bass J, Sigel JE, Xue W, Schluchter M, Jaworsky C: Lipidized dermatofibromas and their relationship to serum lipids. J Am Acad Dermatol; 2006 Mar;54(3):494-8
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  • Lesion location on the body was grouped into 4 sites: leg, thigh, trunk, and upper extremity.
  • Of the 23 patients in the experimental group, 10 had lesions on the legs, 5 had lesions on the thighs, 2 had lesions on the trunk, and 5 had lesions on the upper extremities.
  • Of the 41 patients in the control group, 15 had lesions on the legs, 7 had lesions on the thighs, 9 had lesions on the trunk, and 10 had lesions on the upper extremities.
  • CONCLUSIONS: Our data show that lipidized dermatofibromas do not differ clinically from nonlipidized dermatofibromas in age distribution of patients, tumor location, or underlying serum lipid levels.
  • [MeSH-major] Cholesterol / blood. Histiocytoma, Benign Fibrous / blood. Skin Neoplasms / blood

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  • (PMID = 16488302.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 97C5T2UQ7J / Cholesterol
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20. Alexis AF, Sergay AB, Taylor SC: Common dermatologic disorders in skin of color: a comparative practice survey. Cutis; 2007 Nov;80(5):387-94
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  • [Title] Common dermatologic disorders in skin of color: a comparative practice survey.
  • There is a paucity of data on the epidemiology of dermatologic disease in populations with skin of color.
  • We reviewed the diagnosis codes of 1412 patient visits from August 2004 through July 2005 at the Skin of Color Center at St. Luke's-Roosevelt Hospital Center, in New York.
  • During visits by white patients, the 5 most common diagnoses recorded were acne (ICD-9 706.1); lesion of unspecified behavior (ICD-9 238.2); benign neoplasm of skin of trunk (ICD-9 216.5); contact dermatitis and other eczema, unspecified cause (ICD-9 692.9); and psoriasis (ICD-9 696. 1).
  • [MeSH-major] Skin Diseases / diagnosis. Skin Diseases / ethnology
  • [MeSH-minor] Acne Vulgaris / diagnosis. Acne Vulgaris / ethnology. African Continental Ancestry Group. Dermatitis, Contact / diagnosis. Dermatitis, Contact / ethnology. Dermatitis, Seborrheic / diagnosis. Dermatitis, Seborrheic / ethnology. Eczema / diagnosis. Eczema / ethnology. European Continental Ancestry Group. Humans. Psoriasis / diagnosis. Psoriasis / ethnology. Retrospective Studies. Skin Neoplasms / diagnosis. Skin Neoplasms / ethnology

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  • (PMID = 18189024.001).
  • [ISSN] 0011-4162
  • [Journal-full-title] Cutis
  • [ISO-abbreviation] Cutis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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21. Lucas A, Betlloch I, Planelles M, Martínez T, Pérez-Crespo M, Mataix J, Belinchón I: Non-melanocytic benign skin tumors in children. Am J Clin Dermatol; 2007;8(6):365-9
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  • [Title] Non-melanocytic benign skin tumors in children.
  • BACKGROUND: Dermatologists often attend children with benign skin tumors and cysts.
  • The decision to perform dermatologic surgery in children may be difficult to make, especially in cases of benign tumors.
  • OBJECTIVE: The objective of this study was to determine the nature of non-melanocytic benign skin tumors amenable to dermatologic surgery in children.
  • METHODS: Histopathologic studies of skin tumors in children treated by our department between January 2004 and December 2005 were studied.
  • Age, sex, type of tumor, diagnostic category, site, size, reason for removal, type of anesthesia, and any other associated disorders were recorded.
  • RESULTS: The records revealed that 121 patients presented 129 non-melanocytic benign skin tumors (73 in boys and 56 in girls).
  • Tumors were located on the head and neck (45.7%), trunk (34.1%), and limbs (20.1%).
  • The reasons that led to removal of the tumors were: increase in the size of the tumor (49%); various types of discomfort, such as severe itching or pain (30%); parental concern (4%); diagnostic uncertainty (16%); and esthetic reasons (1%).
  • CONCLUSION: There is a wide diversity of non-melanocytic benign skin tumors in children, some of which require surgical treatment.
  • Pilomatrixomas appear to be the most frequent benign tumors; there are also high frequencies of infundibular cysts, pyogenic granulomas, and viral tumors.
  • [MeSH-major] Skin Neoplasms / pathology

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  • (PMID = 18039019.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
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22. de Feraudy S, Fletcher CD: Intradermal nodular fasciitis: a rare lesion analyzed in a series of 24 cases. Am J Surg Pathol; 2010 Sep;34(9):1377-81
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  • Nodular fasciitis, a benign myofibroblastic proliferation that usually occurs in the subcutaneous tissues of the upper extremities, trunk, as well as head and neck of young adults, is not widely recognized to arise primarily within the dermis.
  • Nine cases (37.5%) arose on limbs, 9 cases (37.5%) on the trunk, and 6 (25%) on the head and neck.
  • Only one tumor "recurred" locally.
  • In summary, intradermal nodular fasciitis occurs most commonly on the limbs and trunk of young adults, shows morphologic features similar to nodular fasciitis at conventional sites and should not be confused with sarcoma.
  • [MeSH-major] Dermis / pathology. Fasciitis / pathology. Skin Diseases / pathology

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  • (PMID = 20716998.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers
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23. Bowen AR, LeBoit PE: Fibroepithelioma of pinkus is a fenestrated trichoblastoma. Am J Dermatopathol; 2005 Apr;27(2):149-54
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  • The delineation of trichoblastoma as the general term for the benign counterpart of BCC raises the possibility that the fibroepithelioma of Pinkus (FEP) would be better classified under that rubric.
  • Unlike the common types of BCC, FEP has an overwhelming predilection for the trunk and extremities, and only 5% of tumors are set in a dermis with significant amounts of solar elastosis.
  • FEP also shows retention of Merkel cells, a characteristic of benign neoplasms with follicular germinative differentiation but not in general of BCC.
  • [MeSH-major] Carcinoma, Basal Cell / classification. Hair Diseases / pathology. Neoplasms, Fibroepithelial / classification. Neoplasms, Fibroepithelial / pathology. Skin Neoplasms / classification
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Child. Female. Humans. Immunohistochemistry. Male. Middle Aged. Sex Factors

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  • (PMID = 15798442.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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24. Cibull TL, Billings SD: Cutaneous malignant ossifying fibromyxoid tumor. Am J Dermatopathol; 2007 Apr;29(2):156-9
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  • [Title] Cutaneous malignant ossifying fibromyxoid tumor.
  • The tumor, partially surrounded by a shell of woven and lamellar bone, had a lobular arrangement of highly cellular islands of tumor cells embedded in a variably fibrous to myxoid stroma.
  • Areas of tumor necrosis were present.
  • The tumor was diagnosed as an ossifying fibromyxoid tumor (OFMT).
  • OFMT is a rare tumor first described in 1989.
  • OFMT usually present in adults on the extremities or trunk.
  • Most are histologically bland and apparently benign tumors, but OFMT with high nuclear grade, high cellularity, and >2 MF/50 high-power fields have shown potential for aggressive behavior including metastasis.
  • Given the histologic features, this tumor was considered a malignant OFMT.
  • [MeSH-major] Buttocks. Fibroma / pathology. Neoplasms, Bone Tissue / pathology. Sarcoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Ossification, Heterotopic

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  • (PMID = 17414437.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Rodríguez-Martín M, Sánchez González R, Sáez-Rodríguez M, García-Bustínduy M, Martín-Herrera A, Noda-Cabrera A: An unusual case of congenital linear eccrine spiradenoma. Pediatr Dermatol; 2009 Mar-Apr;26(2):180-3
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  • Eccrine spiradenoma (ES) is a benign uncommon tumor of skin adnexa with a characteristic clinical and histopathological presentation.
  • Typically, it presents as a painful, slow growing and solitary nodule on the head or upper trunk in adult patients.

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  • (PMID = 19419467.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Ibrahim M, Shwayder T: Hobnail hemangioma in a nine-year-old boy: a rare case presented with dermoscopy. Dermatol Online J; 2010;16(4):7
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  • Hobnail hemangioma is a benign vascular tumor that typically occurs on the trunk and extremities.
  • [MeSH-major] Hemangioma / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 20409414.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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27. Zedek DC, White WL, McCalmont TH: Desmoplastic cellular neurothekeoma: Clinicopathological analysis of twelve cases. J Cutan Pathol; 2009 Nov;36(11):1185-90
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  • BACKGROUND: Cellular neurothekeoma is a benign lesion most commonly found on the face and upper extremities in the first two decades of life.
  • The site was the head and neck in 3 cases, upper extremity in 4, lower extremity in 2, and trunk/abdomen in 3.
  • CONCLUSIONS: The immunohistochemical staining pattern, clinical findings, and benign nature are similar to "conventional" cellular neurothekeomas.
  • The differential diagnosis includes desmoplastic melanocytic lesions, desmoplastic spindle cell carcinoma, dermatofibroma, "immature" scar, plexiform fibrohistiocytic tumor, perineurioma, and piloleiomyoma.
  • [MeSH-major] Neurothekeoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Young Adult

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  • (PMID = 19469877.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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28. Wang WL, Patel KU, Coleman NM, Smith-Zagone MJ, Ivan D, Reed JA, López-Terrada D, Lazar AJ, Prieto VG: COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin. Am J Dermatopathol; 2010 Apr;32(2):149-53
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  • [Title] COL1A1:PDGFB chimeric transcripts are not present in indeterminate fibrohistiocytic lesions of the skin.
  • Indeterminate fibrohistiocytic lesions of the skin share histological and immunohistochemical features of both benign fibrous histiocytoma/dermatofibroma and dermatofibrosarcoma protuberans (DFSP).
  • The most common site was the extremities (n = 8) followed by the trunk (n = 2) and the head and neck region (n = 2).
  • Of the 6 patients with follow-up, 2 had residual tumor excised, but no patient developed a recurrence.
  • [MeSH-major] Chimera / genetics. Collagen Type I / genetics. Dermatofibrosarcoma / genetics. Histiocytoma, Benign Fibrous / genetics. Proto-Oncogene Proteins c-sis / genetics. Skin Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Biopsy. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Histiocytes / metabolism. Histiocytes / pathology. Humans. Immunohistochemistry. Male. Middle Aged. Prevalence. Retrospective Studies. Skin / metabolism. Skin / pathology


29. Gleason BC, Fletcher CD: Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol; 2008 Mar;32(3):354-62
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  • [Title] Deep "benign" fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential.
  • Benign fibrous histiocytoma (FH) is one of the most common mesenchymal neoplasms of the skin.
  • Deep benign FH is an uncommon and poorly recognized clinical subtype that arises in subcutaneous or deep soft tissue.
  • The most common anatomic location was the extremities (58%); the remainder arose on the head and neck (22%), trunk (11%), and in the deep soft tissue of the retroperitoneum, mediastinum, or pelvis (9%).
  • Of the 37 patients for whom clinical follow-up was available (median, 40 mo), 8 (22%) had a local recurrence; in all 8 cases, the tumor had been marginally or incompletely excised.
  • The metastasizing tumors were large (6 and 9 cm) and 1 had tumor necrosis but they were otherwise histologically identical to the nonmetastasizing lesions.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Neoplasm Metastasis / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, CD34 / analysis. Child. Desmin / analysis. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mitosis. Necrosis. Neoplasm Recurrence, Local

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  • (PMID = 18300816.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Desmin
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30. Samaila MO, Mbibu HN, Oluwole OP: Human mycetoma. Surg Infect (Larchmt); 2007 Oct;8(5):519-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • However, the disease may present without these characteristic features, thus causing diagnostic difficulty with other chronic granulomatous infections such as tuberculosis or benign skin lesions.
  • Clinical presentation included pigmented cutaneous nodules, depigmented spots, multiple discharging sinuses, or a fungating mass with bone erosion, involving almost any part of the body (face, trunk, and leg).
  • The range of clinical misdiagnoses included skin tuberculosis, fibroma, amelanotic melanoma, basal-cell carcinoma, and brain tumor.
  • The presentation and clinical course may be confused with those of many skin diseases.
  • Knowledge of mycetoma pathology is important for prompt diagnosis and treatment of this indolent clinical entity.
  • [MeSH-major] Mycetoma / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged

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  • (PMID = 17999585.001).
  • [ISSN] 1096-2964
  • [Journal-full-title] Surgical infections
  • [ISO-abbreviation] Surg Infect (Larchmt)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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31. Wollina U, Hansel G, Schönlebe J, Haroske G: Myxoid neurothekeoma--a painful case in a less common location. Dermatol Online J; 2009;15(4):3
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  • Myxoid neurothekeoma is a rare benign asymptomatic tumor of the skin.
  • We present a 19-year-old female patient with a relapsing tumor of this type in a less common localization, i.e., lower trunk, and with painful sensations under mechanical pressure.
  • [MeSH-major] Neurothekeoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Back. Biomarkers, Tumor. Diagnosis, Differential. Female. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Pain / etiology. S100 Proteins / analysis. Subcutaneous Tissue. Young Adult

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  • (PMID = 19450396.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / S100 Proteins
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32. Scalvenzi M, De Natale F, Francia MG, Balato A: Dermoscopy of microvenular hemangioma: report of a case. Dermatology; 2007;215(1):69-71
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  • The tumor cells lacked cellular atypia.
  • Microvenular hemangioma is a rare, slowly growing, benign vascular tumor.
  • It usually presents on the trunk or the extremities of young to middle-aged adults.
  • Microvenular hemangioma is a benign vascular tumor with distinct dermoscopic and histopathological features which enable it to be distinguished from other vascular neoplasms.
  • [MeSH-major] Dermoscopy / methods. Hemangioma, Capillary / pathology. Skin Neoplasms / pathology

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  • [Copyright] 2007 S. Karger AG, Basel
  • (PMID = 17587844.001).
  • [ISSN] 1421-9832
  • [Journal-full-title] Dermatology (Basel, Switzerland)
  • [ISO-abbreviation] Dermatology (Basel)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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33. Moosavi C, Jha P, Fanburg-Smith JC: An update on plexiform fibrohistiocytic tumor and addition of 66 new cases from the Armed Forces Institute of Pathology, in honor of Franz M. Enzinger, MD. Ann Diagn Pathol; 2007 Oct;11(5):313-9
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  • [Title] An update on plexiform fibrohistiocytic tumor and addition of 66 new cases from the Armed Forces Institute of Pathology, in honor of Franz M. Enzinger, MD.
  • The seminal article of Drs Franz Enzinger and Renyuan Zhang in 1988 defined plexiform fibrohistiocytic tumor (PFHT) as a distinctive entity.
  • Twenty-eight cases occurred in the upper extremity (mostly forearm), 16 in lower extremity, 11 in trunk, 9 in head and neck, and 2 of unknown site.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Actins / metabolism. Adolescent. Adult. Aged. Antigens, CD / metabolism. Antigens, Differentiation, Myelomonocytic / metabolism. Child. Child, Preschool. Female. Humans. Immunophenotyping. Infant. Male. Middle Aged. Neurothekeoma / diagnosis. Neurothekeoma / metabolism. Neurothekeoma / pathology

  • MedlinePlus Health Information. consumer health - Skin Cancer.
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  • (PMID = 17870015.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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