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1. Zhuang L, Lee CS, Scolyer RA, McCarthy SW, Zhang XD, Thompson JF, Screaton G, Hersey P: Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor-related apoptosis-inducing ligand. Hum Pathol; 2006 Oct;37(10):1286-94
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  • [Title] Progression in melanoma is associated with decreased expression of death receptors for tumor necrosis factor-related apoptosis-inducing ligand.
  • Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis in melanoma by interaction with death receptors TRAIL-R1 (DR4) or TRAIL-R2 (DR5) on melanoma cells or resists apoptosis by interaction with decoy receptors TRAIL-R3 (DcR1) or TRAIL-R4 (DcR2).
  • Immunohistochemical staining for DR4, DR5, and DcR1/DcR2 was performed on formalin-fixed paraffin-embedded sections of 100 cases of primary melanoma, metastatic melanoma, and benign nevi.
  • Percentage expressions of DR4 versus DR5 in benign nevi, primary melanoma, and melanoma metastases were 40% versus 90%, 69% versus 98%, and 55% versus 66%, respectively.
  • DcR1/DcR2 was found in 75% of benign nevi, 62% of primary melanomas, and 74% melanoma metastases.
  • [MeSH-major] Apoptosis Regulatory Proteins / metabolism. Melanoma / metabolism. Membrane Glycoproteins / metabolism. Nevus / metabolism. Skin Neoplasms / metabolism. Tumor Necrosis Factor-alpha / metabolism
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cell Count. Disease Progression. Disease-Free Survival. Female. Humans. Immunohistochemistry. Lymph Nodes / metabolism. Lymph Nodes / pathology. Lymphatic Metastasis. Male. Middle Aged. Subcutaneous Tissue / metabolism. Subcutaneous Tissue / pathology. Survival Rate. TNF-Related Apoptosis-Inducing Ligand


2. Saadat P, Doostan A, Vadmal MS: Folliculosebaceous smooth muscle hamartoma. J Am Acad Dermatol; 2007 Jun;56(6):1021-5
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  • Cutaneous hamartomas are a group of heterogenous benign skin conditions demonstrating epithelial and mesenchymal components in varying proportions.
  • Folliculosebaceous (cystic) hamartomas comprise a distinct group of uncommon cutaneous tumor-like malformations.

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  • (PMID = 17504719.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Glick A, Ryscavage A, Perez-Lorenzo R, Hennings H, Yuspa S, Darwiche N: The high-risk benign tumor: evidence from the two-stage skin cancer model and relevance for human cancer. Mol Carcinog; 2007 Aug;46(8):605-10
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  • [Title] The high-risk benign tumor: evidence from the two-stage skin cancer model and relevance for human cancer.
  • Benign tumors that form following chemical initiation and promotion in the mouse skin can be grouped into two classes.
  • The majority of papillomas do not progress to squamous cell carcinoma (SCC), and these are designated as low-risk or terminally benign papillomas.
  • In standard two-stage carcinogenesis studies both tumor types are present, but grossly indistinguishable.
  • [MeSH-major] Carcinoma, Squamous Cell / etiology. Disease Models, Animal. Papilloma / etiology. Skin Neoplasms / etiology

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  • (PMID = 17538943.001).
  • [ISSN] 0899-1987
  • [Journal-full-title] Molecular carcinogenesis
  • [ISO-abbreviation] Mol. Carcinog.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA117957; United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Review
  • [Publication-country] United States
  • [Number-of-references] 27
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4. Ali F, Brown A, Gottwald L, Thomas J: Basal cell carcinoma with matrical differentiation in a transplant patient: a case report and review of the literature. J Cutan Pathol; 2005 Jul;32(6):445-8
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  • BACKGROUND: Shadow cells, characterized by basaloid squamous cells with a distinct well-defined border and a central unstained area as a shadow of lost nuclei, are characteristic of pilomatricoma, a distinct neoplasm of hair matrix differentiation.
  • The presence of shadow cells within tumor islands composed of follicular germinative cells of an otherwise classic basal cell carcinoma (BCC) has been considered as a distinct diagnostic category of BCC with matrical differentiation.
  • In these areas, the tumor nodules were connected to the epidermis, whereas in others, it extended deep into the reticular dermis to the subcutaneous fat junction.
  • Elsewhere, the majority of the tumor contained a population of shadow cells, similar to those in pilomatricoma, with basaloid-appearing matrical cells in the periphery.
  • Areas of cystic degeneration were present throughout the tumor.
  • CONCLUSION: BCC with matrical differentiation is a distinct pathologic entity and a rare subtype of BCC featuring shadow and matrical cells, typically seen in pilomatricoma, a benign hair matrix neoplasm.
  • This tumor has not yet been reported in an immunosuppressed transplant patient.
  • [MeSH-major] Carcinoma, Basal Cell / immunology. Carcinoma, Basal Cell / pathology. Heart Transplantation. Immunocompromised Host. Skin Neoplasms / immunology. Skin Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Hair Diseases / pathology. Hand / pathology. Humans. Male. Middle Aged. Pilomatrixoma / pathology

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  • (PMID = 15953381.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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5. Ahokas K, Skoog T, Suomela S, Jeskanen L, Impola U, Isaka K, Saarialho-Kere U: Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis. J Invest Dermatol; 2005 Apr;124(4):849-56
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  • [Title] Matrilysin-2 (matrix metalloproteinase-26) is upregulated in keratinocytes during wound repair and early skin carcinogenesis.
  • We studied its role in benign skin disorders characterized by epithelial proliferation, in wound repair, skin cancer, and regulation in keratinocyte (KC) cultures.
  • MMP-26 is expressed by laminin-5-positive KC in the migrating area during wound repair, in benign skin disorders characterized by inflammation and microdisruptions of basement membrane, but in intact skin only in hair follicles.
  • Although MMP-26 was expressed in grades I and II squamous cell cancers (SCC), it was not present in dedifferentiated grade III tumors.
  • But in tissue samples it either co-localized or was detected in adjacent cells of same regions with the tumor suppressor p16.
  • In KC and HaCaT cell cultures, 12-phorbol-13-myristate-acetate, epidermal growth factor, tumor necrosis factor-alpha, transforming growth factor-beta1, interleukin-1 (IL-1)beta, IL-6, insulin-like growth factor, gamma-IFN, retinoic acid, dexamethasone, four matrices or ras-transformation were unable to upregulate MMP-26 expression.
  • [MeSH-major] Biomarkers, Tumor / genetics. Carcinoma, Squamous Cell / physiopathology. Keratinocytes / physiology. Matrix Metalloproteinases / genetics. Skin Neoplasms / physiopathology
  • [MeSH-minor] Cell Line, Transformed. Cell Line, Tumor. Gene Expression Regulation, Neoplastic. Humans. Matrix Metalloproteinases, Secreted. Up-Regulation. Wound Healing / physiology

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  • (PMID = 15816845.001).
  • [ISSN] 0022-202X
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.4.24.- / MMP26 protein, human; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.- / Matrix Metalloproteinases, Secreted
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6. Mathew RA, Schlauder SM, Calder KB, Morgan MB: CD117 immunoreactivity in atypical fibroxanthoma. Am J Dermatopathol; 2008 Feb;30(1):34-6
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  • Atypical fibroxanthoma (AFX) is a spindle cell neoplasm of the skin seen typically on sun-damaged skin of the elderly.
  • Though described as a benign entity, local recurrence and distant metastasis have been reported.
  • The percentage of positive cells for CD117 expression among all tumors was approximately 30%.
  • [MeSH-major] Biomarkers, Tumor / analysis. Histiocytoma, Benign Fibrous / metabolism. Proto-Oncogene Proteins c-kit / biosynthesis. Skin Neoplasms / metabolism

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  • [CommentIn] Am J Dermatopathol. 2008 Aug;30(4):401-2 [18645317.001]
  • [CommentIn] Am J Dermatopathol. 2009 Feb;31(1):96-8 [19155737.001]
  • [CommentIn] Am J Dermatopathol. 2008 Dec;30(6):640-2 [19033951.001]
  • (PMID = 18212542.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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7. Tanahashi J, Kashima K, Daa T, Kondo Y, Kuratomi E, Yokoyama S: A case of cutaneous myoepithelial carcinoma. J Cutan Pathol; 2007 Aug;34(8):648-53
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  • [Title] A case of cutaneous myoepithelial carcinoma.
  • BACKGROUND: Cutaneous myoepithelioma, both benign and malignant, is a rare neoplasm composed of neoplastic myoepithelial cells showing diverse histopathological features, and criteria for discriminating benign or malignant have not been fully clarified.
  • PATIENT: We present a case of cutaneous myoepithelial carcinoma in a 62-year-old woman presenting a solid mass in the right back.
  • RESULTS: Resected tumor was located in the whole dermis and subcutis.
  • Tumor cells were all epithelioid, although plasmacytoid and glycogen-rich clear cells were also observed within the large nodules of the deep part.
  • CONCLUSION: The final diagnosis was cutaneous myoepithelial carcinoma.
  • At present, it seems to be difficult to predict the behavior of myoepithelioma of the skin and soft tissue, although atypia and high mitotic rate are reported to be associated with local recurrence and metastasis.
  • [MeSH-major] Myoepithelioma / pathology. Skin Neoplasms / pathology

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  • (PMID = 17640237.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers
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8. Schön M, Kähne T, Gollnick H, Schön MP: Expression of gp130 in tumors and inflammatory disorders of the skin: formal proof of its identity as CD146 (MUC18, Mel-CAM). J Invest Dermatol; 2005 Aug;125(2):353-63
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  • [Title] Expression of gp130 in tumors and inflammatory disorders of the skin: formal proof of its identity as CD146 (MUC18, Mel-CAM).
  • Two antibodies, BT14 and L101, detect a tumor-associated cell surface glycoprotein (gp130) whose properties in normal and diseased skin were assessed, and whose molecular identity was determined in this study.
  • In normal skin, gp130 was constitutively expressed on dermal blood vessels and epidermal appendages, but not in interfollicular epidermis.
  • Marked induction was detected within benign and malignant tumors of various origins including viral warts, basal cell carcinomas, squamous cell carcinomas, metastatic melanomas, and cutaneous T cell lymphomas.
  • Surprisingly, gp130 was also induced in inflammatory skin diseases including psoriasis and allergic contact dermatitis.
  • [MeSH-major] Antigens, CD / metabolism. Carcinoma, Squamous Cell / metabolism. Membrane Glycoproteins / metabolism. Neural Cell Adhesion Molecules / metabolism. Skin Neoplasms / metabolism

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  • (PMID = 16098047.001).
  • [ISSN] 0022-202X
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD146; 0 / MCAM protein, human; 0 / Membrane Glycoproteins; 0 / Neural Cell Adhesion Molecules; GZP2782OP0 / N-Acetylneuraminic Acid
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9. Busam KJ: Desmoplastic Melanoma. Surg Pathol Clin; 2009 Sep;2(3):511-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is typically found in the head and neck region on chronically sun-damaged skin of older individuals.
  • It may simulate a sclerosing melanocytic nevus and various benign and malignant nonmelanocytic lesions.
  • It may be prominent throughout the entire tumor (pure DM) or represent a portion of an otherwise nondesmoplastic melanoma (combined DM).

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  • [Copyright] Copyright © 2009 Elsevier Inc. All rights reserved.
  • (PMID = 26838536.001).
  • [ISSN] 1875-9181
  • [Journal-full-title] Surgical pathology clinics
  • [ISO-abbreviation] Surg Pathol Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Desmoplastic melanoma / Desmoplastic nevus / Melanoma diagnosis / Prognosis / Sarcomatoid skin tumors
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10. van Doorn R, Zoutman WH, Dijkman R, de Menezes RX, Commandeur S, Mulder AA, van der Velden PA, Vermeer MH, Willemze R, Yan PS, Huang TH, Tensen CP: Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73. J Clin Oncol; 2005 Jun 10;23(17):3886-96
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epigenetic profiling of cutaneous T-cell lymphoma: promoter hypermethylation of multiple tumor suppressor genes including BCL7a, PTPRG, and p73.
  • PURPOSE: To analyze the occurrence of promoter hypermethylation in primary cutaneous T-cell lymphoma (CTCL) on a genome-wide scale, focusing on epigenetic alterations with pathogenetic significance.
  • Bisulfite sequence analysis was applied for confirmation and detection of hypermethylation of eight selected tumor suppressor genes.
  • RESULTS: The DNA methylation patterns of CTCLs emerging from differential methylation hybridization analysis included 35 CpG islands hypermethylated in at least four of the 28 studied CTCL samples when compared with benign T-cell samples.
  • Hypermethylation of the putative tumor suppressor genes BCL7a (in 48% of CTCL samples), PTPRG (27%), and thrombospondin 4 (52%) was confirmed and demonstrated to be associated with transcriptional downregulation.
  • In addition, the promoters of the selected tumor suppressor genes p73 (48%), p16 (33%), CHFR (19%), p15 (10%), and TMS1 (10%) were hypermethylated in CTCL.
  • CONCLUSION: Malignant T cells of patients with CTCL display widespread promoter hypermethylation associated with inactivation of several tumor suppressor genes involved in DNA repair, cell cycle, and apoptosis signaling pathways.
  • [MeSH-major] DNA Methylation. DNA-Binding Proteins / genetics. Genes, Tumor Suppressor / physiology. Lymphoma, T-Cell, Cutaneous / genetics. Microfilament Proteins / genetics. Nerve Tissue Proteins / genetics. Nuclear Proteins / genetics. Oncogene Proteins / genetics. Protein Tyrosine Phosphatases / genetics. Skin Neoplasms / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, CD30 / metabolism. Base Sequence. CpG Islands. DNA, Neoplasm / genetics. Epigenesis, Genetic. Female. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Gene Silencing. Genome, Human. Humans. Male. Microarray Analysis. Middle Aged. Molecular Sequence Data. Promoter Regions, Genetic. Receptor-Like Protein Tyrosine Phosphatases, Class 5. Thrombospondins / genetics. Tumor Suppressor Proteins

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  • (PMID = 15897551.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / BCL7A protein, human; 0 / DNA, Neoplasm; 0 / DNA-Binding Proteins; 0 / Microfilament Proteins; 0 / Nerve Tissue Proteins; 0 / Nuclear Proteins; 0 / Oncogene Proteins; 0 / Thrombospondins; 0 / Tumor Suppressor Proteins; 0 / thrombospondin 4; 0 / tumor suppressor protein p73; EC 3.1.3.48 / PTPRG protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.1.3.48 / Receptor-Like Protein Tyrosine Phosphatases, Class 5
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11. Tanaka H, Yamazaki N, Kawabe M, Watanabe H, Nakade M: [Subpectoral lipoma developing to cervix; report of a case]. Kyobu Geka; 2010 Mar;63(3):248-50
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  • The lipoma was dissected successfully from adjacent subclavian artery and vein, brachial nerve, and surrounding muscles through sub-and supra-clavicular small skin incision without cut of the clavicle.
  • Subpectoral lipoma is one of the benign tumor and at the operation less invasive and cosmetically superior approach should be adopted except for inevitable cases.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Lipoma / pathology. Soft Tissue Neoplasms / pathology. Thoracic Neoplasms / pathology

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  • (PMID = 20214358.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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12. Langbein L, Cribier B, Schirmacher P, Praetzel-Wunder S, Peltre B, Schweizer J: New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma. Br J Dermatol; 2008 Sep;159(3):633-45
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  • [Title] New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma.
  • CONCLUSIONS: Syringomas are benign tumours of luminal cells of the lowermost intraglandular sweat duct.
  • [MeSH-major] Adenoma, Sweat Gland / chemistry. Biomarkers, Tumor / analysis. Eccrine Glands / chemistry. Keratin-1 / analysis. Sweat Gland Neoplasms / chemistry

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  • (PMID = 18647305.001).
  • [ISSN] 1365-2133
  • [Journal-full-title] The British journal of dermatology
  • [ISO-abbreviation] Br. J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT1 protein, human; 0 / KRT77 protein, human; 0 / Keratin-1
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13. Ko JY, Kim JE, Kim YH, Ro YS: Cutaneous plexiform schwannomas in a patient with neurofibromatosis type 2. Ann Dermatol; 2009 Nov;21(4):402-5
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  • [Title] Cutaneous plexiform schwannomas in a patient with neurofibromatosis type 2.
  • Plexiform schwannoma is a rare benign neoplasm of the neural sheath characterized by a multinodular plexiform growth pattern.
  • The tumor usually occurs as an isolated finding, although rare cases have been reported in association with neurofibromatosis type 2 (NF2).
  • He had an asymptomatic skin-colored nodule on his neck that had been present for 10 years.
  • A histopathological examination of the skin-colored nodule also showed the typical microscopic features of a plexiform schwannoma, including the characteristic Antoni type A areas showing frequent nuclear palisading and Verocay bodies.
  • Herein we report a rare case of cutaneous plexiform schwannomas in a patient with NF2.

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  • [Cites] Arch Pathol Lab Med. 1996 Apr;120(4):399-401 [8619756.001]
  • [Cites] Cancer. 1995 Oct 1;76(7):1181-6 [8630895.001]
  • [Cites] J Invest Dermatol. 1995 Jan;104(1):74-7 [7798645.001]
  • [Cites] Cell. 1993 Mar 12;72(5):791-800 [8453669.001]
  • [Cites] Histopathology. 1986 Sep;10(9):971-80 [3096870.001]
  • [Cites] Mod Pathol. 1989 Jan;2(1):20-6 [2493641.001]
  • [Cites] Am J Surg Pathol. 1983 Oct;7(7):691-7 [6638259.001]
  • [Cites] Int J Dermatol. 2004 May;43(5):336-40 [15117362.001]
  • [Cites] J Med Genet. 2000 Dec;37(12):897-904 [11106352.001]
  • [Cites] J Dermatol. 2007 Jan;34(1):60-4 [17204104.001]
  • [Cites] Br J Neurosurg. 2005 Feb;19(1):5-12 [16147576.001]
  • [Cites] J Thorac Cardiovasc Surg. 1998 Jan;115(1):240-2 [9451070.001]
  • [Cites] Histopathology. 1998 Mar;32(3):264-70 [9568513.001]
  • (PMID = 20523833.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2861261
  • [Keywords] NOTNLM ; Neurofibromatosis type 2 / Plexiform / Schwannoma
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14. Yeh I, Tran DT, Davis TL, Argenyi ZB: An infiltrative variant of non-neural granular cell tumor: a case report. J Cutan Pathol; 2009 Oct;36 Suppl 1:46-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An infiltrative variant of non-neural granular cell tumor: a case report.
  • Dermal non-neural granular cell tumors are rare tumors of indeterminate lineage that typically present as well-circumscribed tumors with nuclear pleomorphism and mitotic activity.
  • We describe a dermal non-neural granular cell tumor with a distinctive growth pattern with granular cells interspersed between collagen bundles.
  • The immunohistochemical characteristics were similar to those of previously reported dermal non-neural granular cell tumors.
  • Our case could represent a dermal non-neural granular cell tumor with unique architecture, a granular cellular neurothekeoma or a granular cell dermatofibroma.
  • As both dermal non-neural granular cell tumor and cellular neurothekeoma are of indeterminate lineage, our case with features characteristic of both entities may suggest a common precursor or lineage for dermal non-neural granular cell tumor and cellular neurothekeoma.
  • [MeSH-major] Granular Cell Tumor / pathology. Neurothekeoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / metabolism. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / surgery. Humans. Immunohistochemistry. Middle Aged. Scapula / pathology. Scapula / surgery

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  • (PMID = 19187104.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Urquhart JL, Uzieblo A, Kohler S: Detection of HHV-8 in pyogenic granuloma-like Kaposi sarcoma. Am J Dermatopathol; 2006 Aug;28(4):317-21
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  • Kaposi sarcoma (KS) is a low-grade vascular neoplasm associated with human herpesvirus-8 (HHV-8) infection.
  • Recently, we encountered 6 KS tumors that histologically mimicked pyogenic granuloma (PG), a common benign vascular tumor of the skin that usually does not figure in the histologic differential diagnosis of KS.
  • [MeSH-major] Granuloma, Pyogenic / pathology. Herpesvirus 8, Human / isolation & purification. Sarcoma, Kaposi / diagnosis. Sarcoma, Kaposi / virology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, Viral / metabolism. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Nuclear Proteins / metabolism. Phosphoproteins / metabolism

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  • (PMID = 16871034.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Viral; 0 / Nuclear Proteins; 0 / Phosphoproteins; 0 / latent nuclear antigen (LNA)
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16. Temam F, Bizuneh E, Leekassa R: Disseminated form of syringoma (eruptive syringoma) sparing the face-a rare presentation causing diagnostic challenge. Ethiop Med J; 2008 Jul;46(3):273-6
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  • Syringomas are benign neoplasms of the skin commonly appearing around the eye lids.
  • The lesions are asymptomatic, firm, discrete, translucent or skin colored flat-topped papules.
  • [MeSH-major] Sweat Gland Neoplasms / pathology. Syringoma / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans

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  • (PMID = 19271392.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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17. Borenstein M, Mirzabeigi M, Vincek V: Pityrosporum and seborrheic keratosis: an association. Dermatol Online J; 2005;11(2):3
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  • Seborrheic keratoses (SK) are one of the most common benign tumors of the skin.
  • Studies have suggested that human papillomavirus or a benign clonal proliferation of epidermal cells is involved in the pathogenesis of some SK's, however, this issue remains to be resolved.

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  • (PMID = 16150211.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Florell SR, Cessna M, Lundell RB, Boucher KM, Bowen GM, Harris RM, Petersen MJ, Zone JJ, Tripp S, Perkins SL: Usefulness (or lack thereof) of immunophenotyping in atypical cutaneous T-cell infiltrates. Am J Clin Pathol; 2006 May;125(5):727-36
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  • [Title] Usefulness (or lack thereof) of immunophenotyping in atypical cutaneous T-cell infiltrates.
  • Our purpose was to evaluate the interobserver concordance for the diagnoses of mycosis fungoides (MF), atypical dermatoses (AD), and benign dermatoses (BD) and the impact of T-cell immunophenotyping on the diagnoses MF, AD, and BD.
  • Specimens of MF (n = 57), AD (n = 27), BD and normal skin (n = 54) were reviewed by 2 hematopathologists and 1 dermatopathologist to establish diagnostic interobserver concordance by routine morphologic examination.
  • The interobserver concordance was fair to moderate compared with the original diagnosis.
  • Immunophenotyping generally resulted in downgrading of the reaction pattern but was helpful in distinguishing MF from benign dermatoses.
  • [MeSH-major] Immunophenotyping. Leukemic Infiltration / diagnosis. Mycosis Fungoides / diagnosis. Skin Diseases / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, CD / metabolism. Biomarkers, Tumor / metabolism. CD4-CD8 Ratio. Female. Humans. Male. Middle Aged. Observer Variation. ROC Curve. Reproducibility of Results

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  • (PMID = 16707374.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / K23 RR 17525-01
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers, Tumor
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19. Calcaterra R, Franco G, Valenzano M, Fazio R, Morrone A: Clinical features and treatment of dermatosis papulosa nigra in migrants to Italy. Skinmed; 2010 Jul-Aug;8(4):207-9
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  • Dermatosis papulosa nigra (DPN) is a benign epithelial tumor that is common in dark-skinned people.
  • Although the diagnosis is easily made on medical examination, DPN is characterized by a chronic and worsening course.
  • Therefore, even if DPN is a benign disease, the lesions are unaesthetic and the therapeutic options are quite inefficient.
  • [MeSH-major] Facial Dermatoses / pathology. Patient Education as Topic / methods. Skin Pigmentation
  • [MeSH-minor] Adolescent. Adult. Child. Continental Population Groups. Diagnosis, Differential. Emigrants and Immigrants. Female. Follow-Up Studies. Humans. Italy. Male. Middle Aged. Prospective Studies. Risk Factors. Young Adult

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  • (PMID = 21137605.001).
  • [ISSN] 1540-9740
  • [Journal-full-title] Skinmed
  • [ISO-abbreviation] Skinmed
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Zaballos P, Puig S, Llambrich A, Malvehy J: Dermoscopy of dermatofibromas: a prospective morphological study of 412 cases. Arch Dermatol; 2008 Jan;144(1):75-83
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  • SETTINGS: Dermatofibromas were collected in the Departments of Dermatology of the Hospital de Sant Pau i Santa Tecla, Tarragona, Spain, and Hospital de Sant Llatzer, Palma de Mallorca, Spain.
  • CONCLUSION: The most common pattern associated with dermatofibroma is the classic dermoscopic pattern (pigment network and central white patch), but this tumor has a wide range of presentations.
  • [MeSH-major] Dermoscopy / methods. Histiocytoma, Benign Fibrous / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 18209171.001).
  • [ISSN] 1538-3652
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Davari P, Hebert JL, Albertson DG, Huey B, Roy R, Mancianti ML, Horvai AE, McDaniel LD, Schultz RA, Epstein EH Jr: Loss of Blm enhances basal cell carcinoma and rhabdomyosarcoma tumorigenesis in Ptch1+/- mice. Carcinogenesis; 2010 Jun;31(6):968-73
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  • Basal cell carcinomas (BCCs) have relative genomic stability and relatively benign clinical behavior but whether these two are related causally is unknown.
  • Highly recurrent but different copy number changes were associated with the two tumor types and included losses of chromosomes 4 and 10 in all BCCs and gain of chromosome 10 in 80% of RMSs.
  • Despite the quantitative differences, there was no dramatic qualititative difference in the BCC or RMS tumors associated with the mutant Blm genotype.

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  • [Cites] Genes Chromosomes Cancer. 2008 Jan;47(1):71-83 [17943968.001]
  • [Cites] Cancer Res. 2007 Nov 1;67(21):10103-5 [17974949.001]
  • [Cites] Nat Rev Cancer. 2008 Oct;8(10):743-54 [18813320.001]
  • [Cites] Dermatol Surg. 2009 Jan;35(1):131-4 [19076197.001]
  • [Cites] BMC Cancer. 2009;9:140 [19432957.001]
  • [Cites] Cancer Res. 2009 Jul 15;69(14):5768-75 [19584276.001]
  • [Cites] Nat Rev Cancer. 2009 Sep;9(9):644-54 [19657341.001]
  • [Cites] Leuk Res. 2010 Feb;34(2):210-20 [19709744.001]
  • [Cites] Nat Med. 1999 Nov;5(11):1285-91 [10545995.001]
  • [Cites] Nat Genet. 2000 Dec;26(4):424-9 [11101838.001]
  • [Cites] Hum Mol Genet. 2001 Apr;10(7):741-6 [11257107.001]
  • [Cites] Annu Rev Genomics Hum Genet. 2000;1:409-59 [11701636.001]
  • [Cites] Nat Genet. 2002 Jan;30(1):6-7 [11753379.001]
  • [Cites] Carcinogenesis. 2002 May;23(5):727-33 [12016144.001]
  • [Cites] Science. 2002 Sep 20;297(5589):2013 [12242432.001]
  • [Cites] Science. 2002 Sep 20;297(5589):2051-3 [12242442.001]
  • [Cites] Nat Genet. 2003 Jan;33(1):5-6 [12509771.001]
  • [Cites] Hum Mol Genet. 2003 Nov 1;12(21):2837-44 [12952869.001]
  • [Cites] Curr Mol Med. 2003 Nov;3(7):589-96 [14601634.001]
  • [Cites] DNA Repair (Amst). 2003 Dec 9;2(12):1387-404 [14642567.001]
  • [Cites] Cancer Res. 2003 Dec 15;63(24):8578-81 [14695165.001]
  • [Cites] Cancer Res. 2004 Jul 1;64(13):4385-9 [15231643.001]
  • [Cites] Science. 1983 Aug 26;221(4613):851-3 [6879180.001]
  • [Cites] Hum Genet. 1985;71(3):187-91 [4065890.001]
  • [Cites] Proc Natl Acad Sci U S A. 1989 Jan;86(2):670-4 [2911598.001]
  • [Cites] Medicine (Baltimore). 1993 Nov;72(6):393-406 [8231788.001]
  • [Cites] J Biol Chem. 1994 Nov 25;269(47):29838-45 [7961977.001]
  • [Cites] Nucleic Acids Res. 1994 Nov 11;22(22):4566-73 [7527136.001]
  • [Cites] Cell. 1995 Nov 17;83(4):655-66 [7585968.001]
  • [Cites] Science. 1996 Apr 12;272(5259):258-62 [8602509.001]
  • [Cites] Cancer Genet Cytogenet. 1997 Jan;93(1):100-6 [9062585.001]
  • [Cites] Genes Dev. 1998 Nov 1;12(21):3382-93 [9808625.001]
  • [Cites] Oncogene. 1998 Nov 19;17(20):2565-71 [9840919.001]
  • [Cites] Genomics. 1998 Dec 15;54(3):443-52 [9878247.001]
  • [Cites] Genome Res. 2005 Feb;15(2):302-11 [15687294.001]
  • [Cites] Int J Oncol. 2005 Dec;27(6):1567-75 [16273213.001]
  • [Cites] N Engl J Med. 2005 Nov 24;353(21):2262-9 [16306523.001]
  • [Cites] J Med Genet. 2006 Feb;43(2):148-52 [15964893.001]
  • [Cites] Nucleic Acids Res. 2006;34(8):e58 [16670425.001]
  • [Cites] BMC Cancer. 2006;6:96 [16620391.001]
  • [Cites] Cancer Res. 2006 Jul 1;66(13):6606-14 [16818633.001]
  • [Cites] EMBO J. 2006 Jul 26;25(14):3422-31 [16858412.001]
  • [Cites] Mol Cell Biol. 2006 Sep;26(17):6713-26 [16914751.001]
  • [Cites] Cell. 2006 Nov 17;127(4):679-95 [17110329.001]
  • [Cites] J Cell Biol. 2007 Jul 2;178(1):9-14 [17591918.001]
  • [Cites] Mol Cancer Res. 2007 Jul;5(7):713-24 [17634426.001]
  • [Cites] Cell Mol Life Sci. 2007 Sep;64(17):2306-22 [17571213.001]
  • [Cites] Cancer Res. 2008 May 15;68(10):3558-60; discussion 3560-1 [18483234.001]
  • (PMID = 19995795.001).
  • [ISSN] 1460-2180
  • [Journal-full-title] Carcinogenesis
  • [ISO-abbreviation] Carcinogenesis
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / CA81888; United States / NCI NIH HHS / CA / CA84118
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] EC 3.6.1.- / Bloom syndrome protein; EC 3.6.4.12 / RecQ Helicases
  • [Other-IDs] NLM/ PMC2878356
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22. Müller CS, Tilgen W, Kutzner H, Pföhler C: Recurring mixed-type neurothekeoma of the face. Dermatoendocrinol; 2009 Jul;1(4):220-2
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  • BACKGROUND: Neurothekeomas are rare, benign neoplasms, typically occurring in younger patients with a remarkable predilection for the female population.
  • The nomenclature and derivation of these tumors is controversial.
  • The rarity of this unusual skin tumor in daily routine histopathologic findings prompted the following report.
  • Multiple treatments with laser surgery were performed and yielded no persistent remission of the tumor.
  • Histopathologic examination revealed a non-encapsulated dermal tumor, composed of multiple, closely situated medium-sized nodules, separated by a myxoid collagenrich stroma, without epidermal alteration.
  • In summary, due to the histoarchitecture and immunoprofile of the tumor, a mixed-type cellular neurothekeoma was diagnosed.
  • The aim of this report is to help to avoid misdiagnoses of malignant mesenchymal tumors with serious consequences, including extensive surgical therapy or radiation.

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  • [Cites] Histopathology. 1998 May;32(5):414-22 [9639116.001]
  • [Cites] Pathologe. 1999 Mar;20(2):98-109 [10320997.001]
  • [Cites] Mod Pathol. 2004 Feb;17(2):230-4 [14685254.001]
  • [Cites] Am J Surg Pathol. 2007 Mar;31(3):329-40 [17325474.001]
  • [Cites] Histopathology. 1992 May;20(5):397-404 [1587488.001]
  • [Cites] Dermatol Surg. 2005 Jun;31(6):720-2 [15996430.001]
  • [Cites] Am J Surg Pathol. 2007 Jul;31(7):1103-14 [17592278.001]
  • (PMID = 20592794.001).
  • [ISSN] 1938-1980
  • [Journal-full-title] Dermato-endocrinology
  • [ISO-abbreviation] Dermatoendocrinol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2835878
  • [Keywords] NOTNLM ; cellular / nerve sheath tumor / neurothekeoma / skin / soft tissue tumor
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23. Bord A, Valsky DV, Yagel S: Prenatal sonographic diagnosis of congenital perineal skin tag: case report and review of the literature. Prenat Diagn; 2006 Nov;26(11):1065-7
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  • [Title] Prenatal sonographic diagnosis of congenital perineal skin tag: case report and review of the literature.
  • BACKGROUND: Skin tags, or acrochordons, are benign, soft, fleshy tumors that are composed of hyperplastic epidermis covering a dermal connective tissue stalk.
  • METHODS: Case report of a congenital perineal skin tag that presented as a perineal tumor during second-trimester sonographic scan at 23 weeks' gestation.
  • Literature review of the medical literature using Pubmed(R) and the search terms acrochordon, fibroepithelial polyp (FEP), and skin tag.
  • The lesion was removed; pathologic examination revealed a lipomatous skin tag.
  • Literature review showed skin tags associated with different medical conditions.
  • [MeSH-major] Lipomatosis / ultrasonography. Skin Neoplasms / ultrasonography. Ultrasonography, Prenatal

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  • (PMID = 16952203.001).
  • [ISSN] 0197-3851
  • [Journal-full-title] Prenatal diagnosis
  • [ISO-abbreviation] Prenat. Diagn.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 6
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24. Vallbo C, Damber JE: Thrombospondins, metallo proteases and thrombospondin receptors messenger RNA and protein expression in different tumour sublines of the Dunning prostate cancer model. Acta Oncol; 2005;44(3):293-8
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  • [Title] Thrombospondins, metallo proteases and thrombospondin receptors messenger RNA and protein expression in different tumour sublines of the Dunning prostate cancer model.
  • Thrombospondin is a potent inhibitor of angiogenesis and might therefore be important in controlling tumour growth.
  • An earlier study showed that thrombospondin is expressed in benign prostatic hyperplasia (BPH) and high-grade prostatic intraepithelial neoplasia (PIN) but is absent in prostate cancer.
  • [MeSH-major] Antigens, CD36 / analysis. Matrix Metalloproteinases / analysis. Prostatic Neoplasms / pathology. RNA, Messenger / analysis. Thrombospondins / analysis
  • [MeSH-minor] Animals. Antigens, CD / analysis. Antigens, CD47. Cell Adhesion Molecules / analysis. Cell Line, Tumor. Disease Models, Animal. Gene Expression Regulation, Neoplastic. Male. Matrix Metalloproteinase 2 / analysis. Matrix Metalloproteinase 9 / analysis. Neoplasm Transplantation. Prostate / cytology. Rats. Skin Neoplasms / genetics. Skin Neoplasms / pathology. Thrombospondin 1 / analysis

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  • (PMID = 16076702.001).
  • [ISSN] 0284-186X
  • [Journal-full-title] Acta oncologica (Stockholm, Sweden)
  • [ISO-abbreviation] Acta Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD36; 0 / Antigens, CD47; 0 / Cell Adhesion Molecules; 0 / RNA, Messenger; 0 / Thrombospondin 1; 0 / Thrombospondins; 0 / thrombospondin 2; EC 3.4.24.- / Matrix Metalloproteinases; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9
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25. Rotunda AM, Ablon G, Kolodney MS: Lipomas treated with subcutaneous deoxycholate injections. J Am Acad Dermatol; 2005 Dec;53(6):973-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Lipomas are benign neoplasms of mature fat cells.
  • Tumor size, cutaneous reactions, and patients' subjective responses were recorded before and after treatment.
  • [MeSH-major] Deoxycholic Acid / administration & dosage. Lipoma / drug therapy. Skin Neoplasms / drug therapy

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  • [CommentIn] Dermatol Surg. 2006 Sep;32(9):1217 [16970711.001]
  • (PMID = 16310057.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 005990WHZZ / Deoxycholic Acid
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26. Lo CY, Shyur SD, Chu SH, Huang LH, Kao YH, Lei WT, Cheng CH, Lee KH, Chen CK, Liu LC: Juvenile scleroderma: experience in one institution. Asian Pac J Allergy Immunol; 2010 Dec;28(4):279-86
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Scleroderma is a chronic connective tissue disease characterized by hardened or scaly skin and widespread abnormalities of the viscera, which is rare in the pediatric age group.
  • These diagnoses were based on the criteria of the American College of Rheumatology and the clinical manifestations of hard skin.
  • Data recorded included sex, age-at-onset, age-at-diagnosis, laboratory data, family history, trauma history, treatment, and outcomes.
  • One boy had en coup de sabre combined with a posterior fossa tumor.
  • All patients with localized disease ultimately documented a softening of their skin lesions.
  • The prognosis for LS is usually benign, however, the skin may become progressively indurated and it may not only be a skin disease.

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  • (PMID = 21337913.001).
  • [ISSN] 0125-877X
  • [Journal-full-title] Asian Pacific journal of allergy and immunology
  • [ISO-abbreviation] Asian Pac. J. Allergy Immunol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
  • [Chemical-registry-number] 0 / Juvenile-onset scleroderma
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27. Robson A: The pathology of cutaneous T-cell lymphoma. Oncology (Williston Park); 2007 Feb;21(2 Suppl 1):9-12
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  • [Title] The pathology of cutaneous T-cell lymphoma.
  • The diagnosis of cutaneous T-cell lymphoma (CTCL) requires accurate histopathology, including immunocytochemistry, as well as careful clinical appraisal and analysis for T-cell clonality.
  • Mycosis fungoides is an epidermotropic CTCL that evolves through distinct disease stages of patch, plaque, and tumor, often leading to transformation in the final stages.
  • Disease staging is made clinically, and diagnosis may be difficult during the early stages because several common dermatologic conditions share features with MF.
  • Therefore, clinical appraisal plus the presence of characteristic histopathologic features are needed to ensure accurate diagnosis.
  • Clinical information is particularly important in the diagnosis of LyP, as the disease appears malignant histologically, but has a benign clinical course.
  • Several other T-cell lymphomas were defined in a recent classification of these cutaneous lymphomas, and some key features of these disorders are also briefly reviewed.
  • [MeSH-major] Lymphoma, T-Cell, Cutaneous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Antigens, CD30 / metabolism. Antigens, CD4 / metabolism. Antigens, CD8 / metabolism. Antigens, Differentiation, T-Lymphocyte / immunology. Humans. Immunophenotyping. Lymphomatoid Papulosis / pathology. Mycosis Fungoides / pathology. Neoplasm Staging

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  • (PMID = 17474353.001).
  • [ISSN] 0890-9091
  • [Journal-full-title] Oncology (Williston Park, N.Y.)
  • [ISO-abbreviation] Oncology (Williston Park, N.Y.)
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / Antigens, CD4; 0 / Antigens, CD8; 0 / Antigens, Differentiation, T-Lymphocyte
  • [Number-of-references] 1
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28. Schöniger S, Summers BA: Localized, plexiform, diffuse, and other variants of neurofibroma in 12 dogs, 2 horses, and a chicken. Vet Pathol; 2009 Sep;46(5):904-15
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  • In humans, neurofibroma and schwannoma are distinct entities within the group of benign peripheral nerve sheath tumors.
  • In the veterinary literature, these tumors are often classified together simply as benign peripheral nerve sheath tumors, and diagnostic criteria for their subclassification are not well established.
  • We describe peripheral nerve sheath tumors with microscopic, immunohistologic, and ultrastructural features similar to those in subtypes of human neurofibroma in 12 dogs, 2 horses, and 1 chicken.
  • The canine tumors were located in the skin, peripheral nerve, tongue, and large intestine.
  • The equine tumors were located in the subcutis of the neck and axilla.
  • The chicken was a mature white Leghorn chicken with an ocular neoplasm.
  • This investigation shows the existence of identical subtypes of neurofibroma in animals and humans and identifies similarities in tumor location and patient age between animals and humans.
  • This report will allow a more discriminating classification of benign peripheral nerve sheath tumors and probably has a bearing on epidemiology, pathogenesis and prognosis.

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  • (PMID = 19429995.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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29. Xu KJ, Liu YH: [Application of imiquimod and resiquimod in dermatology]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2006 Jun;28(3):445-7
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  • They have anti-virus and anti-tumor activities and can be used as B lymphocyte activators and adjuvants.
  • They are widely used in dermatology to treat virus dermatoses and cutaneous benign or malignant tumors.
  • [MeSH-major] Aminoquinolines / therapeutic use. Condylomata Acuminata / drug therapy. Imidazoles / therapeutic use. Skin Neoplasms / drug therapy

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  • (PMID = 16900654.001).
  • [ISSN] 1000-503X
  • [Journal-full-title] Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae
  • [ISO-abbreviation] Zhongguo Yi Xue Ke Xue Yuan Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Adjuvants, Immunologic; 0 / Aminoquinolines; 0 / Antineoplastic Agents; 0 / Imidazoles; 99011-02-6 / imiquimod; V3DMU7PVXF / resiquimod
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30. Abada RL, Kadiri F, Tawfik N, Benchakroun N, Bouchbika Z, Chekkoury AI, Benchakroun Y, Benider A: [Multiple metastases of a mandibular ameloblastoma]. Rev Stomatol Chir Maxillofac; 2005 Jun;106(3):177-80
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  • INTRODUCTION: Ameloblastoma is a benign odontogenic tumor which can be locally aggressive and invasive.
  • Metastases are rare but possible and must be considered as a malignant form of the tumor.
  • DISCUSSION: The absence of any histological sign of malignity in the primary tumor and in the metastases, as observed in our patient, is remarkable.
  • Progression is very slow, like for the primary tumor.
  • Several factors predictive of metastasis have been described: female gender, age at onset of primary tumor (2nd to 3rd decade) and multiple local recurrences.
  • [MeSH-major] Ameloblastoma / secondary. Mandibular Neoplasms / pathology
  • [MeSH-minor] Female. Follow-Up Studies. Head and Neck Neoplasms / secondary. Humans. Lymphatic Metastasis / pathology. Middle Aged. Paranasal Sinus Neoplasms / secondary. Scalp / pathology. Skin Neoplasms / secondary. Skull Neoplasms / secondary. Zygoma / pathology

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  • (PMID = 15976707.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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31. Kemmerling R, Dietze O, Müller S, Neureiter D: Aspects of the differential diagnosis of clear-cell lesions of the skin in connection with the rare case of a clear-cell atypical fibroxanthoma. Pathol Res Pract; 2009;205(5):365-70
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  • [Title] Aspects of the differential diagnosis of clear-cell lesions of the skin in connection with the rare case of a clear-cell atypical fibroxanthoma.
  • We present a clear-cell atypical fibroxanthoma (CCAFX) and describe the morphological and immunohistochemical aspects of this rare skin lesion.
  • Furthermore, we give an overview of the differential diagnoses of clear-cell lesions of the skin for a practical approach.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged, 80 and over. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Nose / pathology

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  • (PMID = 19155147.001).
  • [ISSN] 1618-0631
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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32. Wadasadawala T, Trivedi S, Gupta T, Epari S, Jalali R: The diagnostic dilemma of primary central nervous system melanoma. J Clin Neurosci; 2010 Aug;17(8):1014-1017
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  • Melanomas are malignant neoplasms of melanocytes developing predominantly in the skin, but occasionally arising from eyes, mucous membranes, and the central nervous system (CNS).
  • The CNS can be affected by a spectrum of melanocytic lesions ranging from diffuse neurocutaneous melanosis, to a focal and benign neoplasm (melanocytoma), and to an overtly malignant tumor (melanoma).
  • Primary CNS melanoma cannot be reliably distinguished from metastatic melanoma on neuroimaging and histopathological characteristics alone: its diagnosis is established only after exclusion of secondary metastatic disease from a cutaneous, mucosal or retinal primary.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebellopontine Angle / pathology. Melanoma / pathology. Parietal Lobe / pathology

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  • (PMID = 20627582.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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33. Estrada-Chavez G, Vega-Memije ME, Lacy-Niebla RM, Toussaint-Caire S: Scalp metastases of a renal cell carcinoma. Skinmed; 2006 May-Jun;5(3):148-50
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  • An 80-year-old man presented with a localized tumor of the right occipital scalp.
  • The tumor was a 1-cm, bright red-purple, ulcerated, and crusted exophytic nodule on a smooth base (Figure 1).
  • It was extirpated with the clinical diagnosis of pyogenic granuloma vs. renal metastasis to the scalp.
  • The patient's medical history included a transurethral prostatic resection 3 years earlier and, 1 year later, a right nephrectomy for a 2-kg kidney tumor verbally reported as "benign."
  • The histopathologic diagnosis of metastatic renal cell carcinoma was supported by immunohistochemistry with positive epithelial membrane antigen staining (Figure 4).
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Head and Neck Neoplasms / diagnosis. Kidney Neoplasms / diagnosis. Scalp / pathology. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Humans. Male. Neoplasm Metastasis


34. Zhang Y, Tang L, Su M, Eisen D, Zloty D, Warshawski L, Zhou Y: Expression of endothelins and their receptors in nonmelanoma skin cancers. J Cutan Med Surg; 2006 Nov-Dec;10(6):269-76
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  • [Title] Expression of endothelins and their receptors in nonmelanoma skin cancers.
  • However, detailed investigation on endothelins in skin malignancies is lacking.
  • OBJECTIVES: This study aims to survey the expression of endothelins and their receptors in keratinocyte-derived benign and malignant tumors of the skin and to test the effects of endothelin inhibitors on the growth and survival of cultured keratinocytes.
  • CONCLUSION: The endothelin signaling pathway, especially ET-1, is activated in basal keratinocyte neoplasms of the skin, such as basal cell carcinoma and seborrheic keratosis.
  • Therefore, endothelin inhibitors potentially offer a novel method for the treatment of some keratinocyte-derived skin tumors.
  • [MeSH-major] Carcinoma, Basal Cell / metabolism. Carcinoma, Squamous Cell / metabolism. Endothelins / metabolism. Receptors, Endothelin / metabolism. Skin Neoplasms / metabolism
  • [MeSH-minor] Biomarkers, Tumor / genetics. Bowen's Disease / metabolism. Endothelin-1 / genetics. Endothelin-2 / genetics. Humans. Immunohistochemistry. Keratosis / metabolism. Keratosis, Seborrheic / metabolism. Polymerase Chain Reaction. RNA, Messenger. Receptor, Endothelin A / metabolism. Receptor, Endothelin B / metabolism. Transcription, Genetic

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  • (PMID = 17241596.001).
  • [ISSN] 1203-4754
  • [Journal-full-title] Journal of cutaneous medicine and surgery
  • [ISO-abbreviation] J Cutan Med Surg
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Endothelin-1; 0 / Endothelin-2; 0 / Endothelins; 0 / RNA, Messenger; 0 / Receptor, Endothelin A; 0 / Receptor, Endothelin B; 0 / Receptors, Endothelin
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35. Zissis D, Zizi-Serbetzoglou A, Glava C, Grammatoglou X, Katsamagkou E, Nikolaidou ME, Vasilakaki T: Glomus tumor of the stomach: a case report. J BUON; 2008 Oct-Dec;13(4):581-4
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  • [Title] Glomus tumor of the stomach: a case report.
  • Glomus tumors are relatively uncommon benign neoplasms, most common in the skin and subcutaneous tissue, but can also occur in the viscera, most often in the stomach.
  • Preoperative diagnosis, when the tumor occurs in the stomach, seems difficult but is important, since glomus tumors of the stomach are essentially benign and amenable to conservative excision, contrary to aggressive gastric neoplasms.
  • Biopsies taken from the lesion showed morphological and immunohistochemical [positivity for alphasmooth muscle actin (alpha-SMA) and vimentin, negativity for CD34, CD117, chromogranin, synaptophysin, desmin and S-100 protein] characteristics attributable to glomus tumor.
  • Histological examination of the tumor confirmed the diagnosis of gastric glomus tumor.
  • [MeSH-major] Glomus Tumor / pathology. Stomach Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Immunohistochemistry. Male

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  • (PMID = 19145686.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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36. Matsumoto T, Kanzaki M, Wachi N, Onuki T: [Surgically treated chest wall schwannoma without entering the pleural space utilizing ultrasonography]. Kyobu Geka; 2009 Jul;62(7):557-9
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  • A 2.5 cm skin incision was made on the tumor.
  • The tumor arising from the intercostal nerve was surgically removed without entering the pleural space.
  • The pathological examination revealed a benign schwannoma.
  • [MeSH-major] Neurilemmoma / surgery. Thoracic Neoplasms / surgery. Thoracic Wall

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  • (PMID = 19588826.001).
  • [ISSN] 0021-5252
  • [Journal-full-title] Kyobu geka. The Japanese journal of thoracic surgery
  • [ISO-abbreviation] Kyobu Geka
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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37. Weyers W, Hörster S, Diaz-Cascajo C: Tumor of follicular infundibulum is Basal cell carcinoma. Am J Dermatopathol; 2009 Oct;31(7):634-41
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  • [Title] Tumor of follicular infundibulum is Basal cell carcinoma.
  • Tumor of follicular infundibulum (TFI) is currently thought to be a benign epithelial neoplasm with follicular differentiation.
  • Those findings prompted us to conclude that TFI may be one of many manifestations of BCC rather than a differential diagnosis of it.
  • [MeSH-major] Carcinoma, Basal Cell / classification. Carcinoma, Basal Cell / pathology. Skin Neoplasms / classification. Skin Neoplasms / pathology

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  • (PMID = 19652582.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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38. Wood S, Nguyen D, Hutton K, Dickson W: Pilomatricomas in Turner syndrome. Pediatr Dermatol; 2008 Jul-Aug;25(4):449-51
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  • Pilomatricomas are benign, cutaneous tumors of the hair matrix cells, which present predominantly in childhood.
  • We report a 10-year-old girl with Turner syndrome who has two pilomatricomas, including one giant tumor.
  • This apparent predisposition may be etiologically related to the abnormalities of hair-bearing skin observed in Turner syndrome.
  • Doctors involved in the diagnosis and management of cutaneous masses in children should be aware of this association.
  • [MeSH-major] Hair Diseases / complications. Pilomatrixoma / complications. Skin Neoplasms / complications. Turner Syndrome / complications


39. Hafner C, Di Martino E, Pitt E, Stempfl T, Tomlinson D, Hartmann A, Landthaler M, Knowles M, Vogt T: FGFR3 mutation affects cell growth, apoptosis and attachment in keratinocytes. Exp Cell Res; 2010 Jul 15;316(12):2008-16
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  • FGFR3 mutations have recently been identified in several benign epidermal skin lesions such as seborrheic keratosis, epidermal nevus and solar lentigo.
  • The functional consequences of these mutations in human skin are as yet unknown.
  • In this study we analyzed the functional effects of the most common FGFR3 mutation in benign skin tumors, the R248C FGFR3 hotspot mutation, in human HaCaT keratinocytes.
  • Our results suggest that an increased cell number at confluence along with a decreased apoptosis may contribute to the development of acanthotic tumors in FGFR3 mutant skin in vivo.

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  • (PMID = 20420824.001).
  • [ISSN] 1090-2422
  • [Journal-full-title] Experimental cell research
  • [ISO-abbreviation] Exp. Cell Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.10.1 / Receptor, Fibroblast Growth Factor, Type 3
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40. Krengel S: Nevogenesis--new thoughts regarding a classical problem. Am J Dermatopathol; 2005 Oct;27(5):456-65
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  • As a consequence, there are two main perspectives to nevi: that of a hamartoma and that of a benign tumor.
  • [MeSH-major] Cell Transformation, Neoplastic. Nevus / physiopathology. Skin Neoplasms / physiopathology

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  • (PMID = 16148419.001).
  • [ISSN] 0193-1091
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 89
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41. Chiu HT, Garcia CK: Familial spontaneous pneumothorax. Curr Opin Pulm Med; 2006 Jul;12(4):268-72
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  • Mutations in this gene were known previously to cause a rare skin disease, Birt-Hogg-Dubé syndrome, an autosomal dominantly inherited disease characterized by benign skin tumors, diverse types of renal cancer, pulmonary cysts, and spontaneous pneumothorax.
  • Two animal models and studies of renal cancers support a tumor-suppressor function for folliculin.
  • [MeSH-major] Genetic Predisposition to Disease. Pneumothorax / genetics. Proteins / genetics. Proto-Oncogene Proteins / genetics. Tumor Suppressor Proteins / genetics

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  • (PMID = 16825879.001).
  • [ISSN] 1070-5287
  • [Journal-full-title] Current opinion in pulmonary medicine
  • [ISO-abbreviation] Curr Opin Pulm Med
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / IK23RR02063201
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / FLCN protein, human; 0 / Proteins; 0 / Proto-Oncogene Proteins; 0 / Tumor Suppressor Proteins
  • [Number-of-references] 50
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42. Chen MK, Su CC, Tsai YL, Chang CC: Minimally invasive endoscopic resection of the submandibular gland: a new approach. Head Neck; 2006 Nov;28(11):1014-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: This study evaluates the benefits of a new approach, endoscopic resection of the submandibular gland through the hyoid midline level skin incision by use of an ultrasonically activated scalpel.
  • Of the 12 patients who underwent excision, 3, 6, and 3 had mixed tumor, sialoadenitis with sialolithiasis, and chronic sialoadenitis, respectively.
  • CONCLUSIONS: Endoscopic resection of the submandibular gland is a feasible method for treatment of benign lesions.
  • The main advantages of this procedure are that the small operative scar is concealed in the submental skin crease, resulting in improved cosmetic results and minimization of the possibility of facial nerve injury.

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  • (PMID = 16933310.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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43. Kaabipour E, Haupt HM, Stern JB, Kanetsky PA, Podolski VF, Martin AM: p16 expression in keratoacanthomas and squamous cell carcinomas of the skin: an immunohistochemical study. Arch Pathol Lab Med; 2006 Jan;130(1):69-73
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  • [Title] p16 expression in keratoacanthomas and squamous cell carcinomas of the skin: an immunohistochemical study.
  • OBJECTIVE: To determine if p16 expression is useful in the differential diagnosis of SCC and KA.
  • DESIGN: We studied the expression of p16 by immunohistochemistry in 24 KAs, 24 infiltrating SCCs of the skin, 4 histologically indeterminate lesions, and 8 nonmalignant keratoses.
  • No significant difference in measures of p16 expression was identified among the KAs, the SCCs, the indeterminate lesions, or the benign keratoses.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Keratoacanthoma / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cell Count. Diagnosis, Differential. Female. Humans. Immunoenzyme Techniques. Keratosis / metabolism. Keratosis / pathology. Male. Middle Aged

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  • (PMID = 16390241.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16
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44. Pouryazdanparast P, Yu L, Cutlan JE, Olsen SH, Fullen DR, Ma L: Diagnostic value of CD163 in cutaneous spindle cell lesions. J Cutan Pathol; 2009 Aug;36(8):859-64
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  • [Title] Diagnostic value of CD163 in cutaneous spindle cell lesions.
  • BACKGROUND: The histologic diagnosis of atypical fibroxanthoma (AFX) can sometimes be challenging.
  • No specific marker exists to confirm the diagnosis other than excluding other entities.
  • CD163 has been shown to have great specificity for tumors of monocyte/histiocyte lineage.
  • In this study, we evaluated the diagnostic utility of CD163 in diagnosing AFX and in identifying skin lesions with histiocytic/dendritic derivation.
  • METHODS: A total of 157 cases, including 14 AFXs, 5 spindle cell squamous cell carcinomas (SCCs), and 7 spindle cell/desmoplastic melanomas, along with other cutaneous spindle cell and histiocytic/fibrohistiocytic lesions, were stained with CD163.
  • Rare spindle cell/desmoplastic melanomas (2/7) and cutaneous leiomyosarcomas (1/5) demonstrated positive staining.
  • CD163 reactivity was seen in 24 of 29 of benign fibrous histiocytomas (BFHs), including 8 of 8 cellular fibrous histiocytomas and 6 of 9 epithelioid cell histiocytomas.
  • The majority of cutaneous histiocytic lesions, including juvenile xanthogranuloma, Langerhans cell histiocytosis and Rosai-Dorfman disease, were positive for CD163.
  • CONCLUSION: CD163 is a useful adjunct in distinguishing AFX from other malignant cutaneous spindle cell tumors and offers improved specificity in identifying cutaneous histiocytic/dendritic lesions.
  • [MeSH-major] Antigens, CD / biosynthesis. Antigens, Differentiation, Myelomonocytic / biosynthesis. Biomarkers, Tumor / biosynthesis. Carcinoma, Squamous Cell / metabolism. Fibrosarcoma / metabolism. Gene Expression Regulation, Neoplastic. Melanoma / metabolism. Receptors, Cell Surface / biosynthesis. Skin Neoplasms / metabolism

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  • [CommentIn] J Cutan Pathol. 2010 Oct;37(10):1119-20 [20602661.001]
  • (PMID = 19040468.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / Biomarkers, Tumor; 0 / CD163 antigen; 0 / Receptors, Cell Surface
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45. Dubb M, Michelow P: Fine needle aspiration cytology of pilomatrixoma and differential diagnoses. Acta Cytol; 2009 Nov-Dec;53(6):683-8
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  • OBJECTIVE: To review the cytologic features of pilomatrixoma to allow a definitive diagnosis at the time of aspiration and correct patient management.
  • STUDY DESIGN: Three patients each presented with a mass lesion and on fine needle aspiration were diagnosed as either having pilomatrixoma or a benign skin adnexal tumor.
  • The diagnosis was confirmed on histology.
  • RESULT: The most consistent and predominant features for diagnosis were basaloid cells, anucleate squamous cells and calcification in an inflammatory background, often with giant cells.
  • Therefore, lack of shadow cells does not preclude correct diagnosis in the presence of the other relevant cytologic features.
  • If all the major components of pilomatrixoma are present in an aspirate, the diagnosis should not be problematic.
  • However, if one component predominates, this may lead to an erroneous diagnosis of other benign and malignant lesions.
  • CONCLUSION: Knowledge of the cytologic features of pilomatrixoma will allow correct patient diagnosis and management.
  • [MeSH-major] Hair Diseases / pathology. Pilomatrixoma / diagnosis. Pilomatrixoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy, Fine-Needle. Child. Diagnosis, Differential. Humans. Middle Aged. Young Adult

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  • (PMID = 20014559.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Kirschner LS, Kusewitt DF, Matyakhina L, Towns WH 2nd, Carney JA, Westphal H, Stratakis CA: A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues. Cancer Res; 2005 Jun 1;65(11):4506-14
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  • [Title] A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues.
  • Carney complex is an autosomal dominant neoplasia syndrome characterized by spotty skin pigmentation, myxomatosis, endocrine tumors, and schwannomas.
  • Although genotype-specific cardiac and adrenal lesions were not seen, benign and malignant thyroid neoplasias were observed in older mice.
  • This spectrum of tumors overlaps that seen in Carney complex patients, confirming the validity of this mouse model.
  • Genetic analysis indicated that allelic loss occurred in a subset of tumor cells, suggesting that complete loss of Prkar1a plays a key role in tumorigenesis.
  • These observations confirm the identity of PRKAR1A as a tumor suppressor gene with specific importance to cyclic AMP-responsive tissues and suggest that these mice may be valuable tools not only for understanding endocrine tumorigenesis but also for understanding inherited predispositions for schwannoma formation.
  • [MeSH-major] Cyclic AMP / physiology. Disease Models, Animal. Multiple Endocrine Neoplasia / genetics. Neurilemmoma / genetics. Proteins / genetics
  • [MeSH-minor] Alleles. Animals. Bone Neoplasms / enzymology. Bone Neoplasms / genetics. Bone Neoplasms / pathology. Cyclic AMP-Dependent Protein Kinase RIalpha Subunit. Female. Genes, Tumor Suppressor. Genetic Predisposition to Disease. Male. Mice. Osteoblasts / cytology. Osteoblasts / physiology. Schwann Cells / cytology. Schwann Cells / physiology. Syndrome. Thymus Gland / cytology. Thymus Gland / physiology. Thyroid Neoplasms / enzymology. Thyroid Neoplasms / genetics. Thyroid Neoplasms / pathology

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  • (PMID = 15930266.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA16058; United States / NICHD NIH HHS / HD / HD01323
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Cyclic AMP-Dependent Protein Kinase RIalpha Subunit; 0 / Prkar1a protein, mouse; 0 / Proteins; E0399OZS9N / Cyclic AMP
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47. Botrus G, Sciot R, Debiec-Rychter M: Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly. Cancer Genet Cytogenet; 2006 Jan 15;164(2):155-8
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  • [Title] Cutaneous aneurysmal fibrous histiocytoma with a t(12;19)(p12;q13) as the sole cytogenetic anomaly.
  • Cytogenetic analysis of the tumor specimen disclosed a 46,XX,t(12;19)(p12;q13) karyotype.
  • Our case highlights the importance of distinguishing this recurrent but benign lesion from similarly appearing malignant skin tumors.
  • Cytogenetic analysis may contribute to the diagnosis of this uncommon but distinctive clinicopathological entity.
  • [MeSH-major] Chromosomes, Human, Pair 19. Chromosomes, Human, Pair 22. Histiocytoma, Benign Fibrous / genetics. Skin Neoplasms / genetics. Translocation, Genetic

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  • (PMID = 16434321.001).
  • [ISSN] 0165-4608
  • [Journal-full-title] Cancer genetics and cytogenetics
  • [ISO-abbreviation] Cancer Genet. Cytogenet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ETS translocation variant 6 protein; 0 / Proto-Oncogene Proteins; 0 / Proto-Oncogene Proteins c-ets; 0 / Repressor Proteins; 0 / Transcription Factors; 0 / proto-oncogene protein bcl-3
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48. Chvapil M, Kielar F, Liska F, Silhankova A, Brendel K: Synthesis and evaluation of long-acting D-penicillamine derivatives. Connect Tissue Res; 2005;46(4-5):242-50
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  • A single injection of either DPA hexyl ester HCl or 3-hexyl(amino) propionitrile into the full thickness skin incision wound in rats significantly lowered the breaking strength of the wound 12 days after injection, indicating the interference with collagen cross-linking.
  • Both agents injected into the breast adenocarcinoma in Fisher rats significantly inhibited tumor growth without any signs of local or systemic toxicity.
  • We conclude that these lipophilic lathyrogens with prolonged effectiveness are suitable in the treatment of pathologies, consisting of excessively cross-linked or deposited collagen (fibrotic adhesions, strictures, stenosis, and scar contractures) and in the treatment of single, solitary tumors, malignant and benign.
  • [MeSH-major] Aminopropionitrile / analysis. Aminopropionitrile / chemical synthesis. Cicatrix, Hypertrophic / drug therapy. Connective Tissue Diseases / drug therapy. Neoplasms / drug therapy. Penicillamine / analogs & derivatives. Penicillamine / chemical synthesis
  • [MeSH-minor] Adenocarcinoma / drug therapy. Alcohols / chemistry. Animals. Collagen / drug effects. Collagen / metabolism. Constriction, Pathologic / drug therapy. Constriction, Pathologic / metabolism. Constriction, Pathologic / physiopathology. Esterification. Female. Hexanols / chemistry. Mammary Neoplasms, Experimental / drug therapy. Molecular Structure. Rats. Rats, Inbred F344. Tissue Adhesions / drug therapy. Tissue Adhesions / metabolism. Tissue Adhesions / physiopathology. Treatment Outcome. Urethral Stricture / drug therapy. Urethral Stricture / metabolism. Urethral Stricture / physiopathology

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  • (PMID = 16546828.001).
  • [ISSN] 0300-8207
  • [Journal-full-title] Connective tissue research
  • [ISO-abbreviation] Connect. Tissue Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Alcohols; 0 / Hexanols; 151-18-8 / Aminopropionitrile; 9007-34-5 / Collagen; GNN1DV99GX / Penicillamine
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49. Patrizi A, Tabanelli M, Misciali C, Orlowski F, Righi A: Benign myoepithelioma in the interdigital space of the foot. Am J Dermatopathol; 2008 Feb;30(1):86-7
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  • [Title] Benign myoepithelioma in the interdigital space of the foot.
  • [MeSH-major] Foot / pathology. Myoepithelioma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. Humans. Immunohistochemistry. Middle Aged

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  • (PMID = 18212555.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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50. Yaqoob N, Kayani N, ul Hasan SH: Painless breast lump in an elderly woman. Secretory breast carcinoma in an elderly woman. Arch Pathol Lab Med; 2006 Jul;130(7):1073-4
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  • Ultrasonographic findings may resemble other well-circumscribed breast carcinomas as well as some benign masses, including fibroadenomas.
  • The tumor was ulcerating through the skin.
  • [MeSH-major] Adenocarcinoma / pathology. Adenocarcinoma / secretion. Bodily Secretions. Breast Neoplasms / pathology. Breast Neoplasms / secretion
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. Humans. Mastectomy, Simple. Middle Aged

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  • (PMID = 16831040.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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51. García-Reyna JC, Rico Martínez G, Vega González IF, Linares LM, Delgado Cedillo EA, Romero Ramírez R: [Musculoskeletal tumor evaluation with 99mTc-Tetrofosmin]. Acta Ortop Mex; 2008 Nov-Dec;22(6):390-6
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  • [Title] [Musculoskeletal tumor evaluation with 99mTc-Tetrofosmin].
  • [Transliterated title] 99mTc-Tetrofosmin en la evaluación de tumores musculoesqueléticos.
  • INTRODUCTION: (99m)Tc-tetrofosmin is an efficient agent as a tumor marker.
  • Several studies have proven its efficiency in detection and localization of tumors of the breast, larynx, thyroid, parathyroid glands, lung, brain, skin, lymphatic and musculoskeletal tissues with a sensitivity and specificity of 95% to 100%.
  • Nevertheless, benign pathology such as active inflammation is a source of false positives and the attending physician must consider the aid of complementary studies such as histopathology.
  • [MeSH-major] Bone Neoplasms / radionuclide imaging. Muscle Neoplasms / radionuclide imaging. Organophosphorus Compounds. Organotechnetium Compounds. Radiopharmaceuticals

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  • (PMID = 19280840.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Clinical Trial; Comparative Study; English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / Organophosphorus Compounds; 0 / Organotechnetium Compounds; 0 / Radiopharmaceuticals; 0 / technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane
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52. Bekou V, Thoma-Uszynski S, Wendler O, Uter W, Schwietzke S, Hunziker T, Zouboulis CC, Schuler G, Sorokin L, Hertl M: Detection of laminin 5-specific auto-antibodies in mucous membrane and bullous pemphigoid sera by ELISA. J Invest Dermatol; 2005 Apr;124(4):732-40
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  • Since detection of disease-specific auto-ab may be critical for diagnosis of MMP, we developed an ELISA with affinity-purified native human LN5.
  • [MeSH-major] Autoantibodies / blood. Cell Adhesion Molecules / immunology. Enzyme-Linked Immunosorbent Assay / methods. Pemphigoid, Benign Mucous Membrane / immunology. Pemphigoid, Bullous / immunology
  • [MeSH-minor] Biomarkers / blood. Carcinoma, Squamous Cell. Cell Line, Tumor. Fluorescent Antibody Technique, Indirect. Humans. Immunoglobulin G / blood. Laminin / immunology. Mucous Membrane / immunology. Prognosis. Sensitivity and Specificity. Skin Neoplasms

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  • (PMID = 15816831.001).
  • [ISSN] 0022-202X
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Biomarkers; 0 / Cell Adhesion Molecules; 0 / Immunoglobulin G; 0 / LAMC2 protein, human; 0 / Laminin; 0 / kalinin; 170834-93-2 / laminin alpha 3
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53. Karbowniczek M, Henske EP: The role of tuberin in cellular differentiation: are B-Raf and MAPK involved? Ann N Y Acad Sci; 2005 Nov;1059:168-73
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  • Tuberous sclerosis complex (TSC) is a tumor suppressor gene syndrome whose manifestations can include seizures, mental retardation, autism, and tumors in the brain, retina, kidney, heart, and skin.
  • Other genetic studies showed that the benign smooth muscle cells of pulmonary lymphangiomyomatosis have the ability to migrate to other organs.
  • [MeSH-major] Gene Expression Regulation, Neoplastic. MAP Kinase Signaling System. Proto-Oncogene Proteins B-raf / physiology. Tumor Suppressor Proteins / physiology
  • [MeSH-minor] Angiomyolipoma / metabolism. Animals. Cell Differentiation. Cell Movement. Humans. Models, Biological. Neoplasm Metastasis. Signal Transduction

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  • (PMID = 16382052.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.11.1 / BRAF protein, human; EC 2.7.11.1 / Proto-Oncogene Proteins B-raf
  • [Number-of-references] 50
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54. Khademi B, Taraghi A, Mohammadianpanah M: Anatomical and histopathological profile of head and neck neoplasms in Persian pediatric and adolescent population. Int J Pediatr Otorhinolaryngol; 2009 Sep;73(9):1249-53
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  • [Title] Anatomical and histopathological profile of head and neck neoplasms in Persian pediatric and adolescent population.
  • BACKGROUND: Neoplasms of the head and neck region are relatively uncommon in childhood.
  • The present study aimed to describe and compare the anatomical and histopathological distribution of head and neck neoplasms in Persian pediatric and adolescent population.
  • METHODS: Patients who presented with primary head and neck tumors were included in this study.
  • Orbital and skin tumors and neoplasms with secondary (metastatic) involvement of the head and neck were excluded from the study.
  • Based on the data obtained from a tertiary referral hospital tumor registry and oncology department, a total of 152 benign and malignant neoplasms of the head and neck in patients aged 19 years or younger (99 boys), whom were reported to this institution between 2000 and 2007, were analyzed in this study.
  • There were 136 (89.5%) malignant tumors and 16 (10.5%) benign neoplasms.
  • Lymphomas [Non-Hodgkin's lymphomas (30%), Hodgkin's disease (25%)], carcinomas (20%), and sarcomas (10.5%) were the most frequent histopathological types.
  • CONCLUSION: The most frequent primary site, malignant histopathological type, and male-female ratio in our study were comparable with other reported series; however, the ratio of benign to malignant lesions is different from most studies.
  • [MeSH-major] Carcinoma / epidemiology. Head and Neck Neoplasms / epidemiology. Lymphoma / epidemiology. Sarcoma / epidemiology

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  • (PMID = 19525017.001).
  • [ISSN] 1872-8464
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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55. Wagamon K, Somach SC, Bass J, Sigel JE, Xue W, Schluchter M, Jaworsky C: Lipidized dermatofibromas and their relationship to serum lipids. J Am Acad Dermatol; 2006 Mar;54(3):494-8
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  • CONCLUSIONS: Our data show that lipidized dermatofibromas do not differ clinically from nonlipidized dermatofibromas in age distribution of patients, tumor location, or underlying serum lipid levels.
  • [MeSH-major] Cholesterol / blood. Histiocytoma, Benign Fibrous / blood. Skin Neoplasms / blood

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  • (PMID = 16488302.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 97C5T2UQ7J / Cholesterol
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56. Vazmitel M, Michal M, Mukensnabl P, Kazakov DV: Syringocystadenoma papilliferum with sebaceous differentiation in an intradermal tubular apocrine component. Report of a case. Am J Dermatopathol; 2008 Feb;30(1):51-3
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  • Syringocystadenoma papilliferum is a benign tumor most commonly located on the scalp or face, and it often arises within a nevus sebaceus of Jadassohn.
  • Although some adnexal neoplasms that develop in association with a nevus sebaceus may exhibit conjoint sebaceous, follicular, or apocrine differentiation, reflecting close embryological relations of the folliculosebaceous-apocrine unit, the feature we report on has not previously been described to the best of our knowledge.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Head and Neck Neoplasms / pathology. Neoplasms, Multiple Primary / pathology. Nevus, Sebaceous of Jadassohn / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology


57. Dubb M, Michelow P, Grayson W: Cytologic features of trichoblastoma in fine needle aspiration biopsies. Acta Cytol; 2009 Nov-Dec;53(6):679-82
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  • OBJECTIVE: To review the cytologic features of trichoblastoma in order to define criteria that may aid in identification of these tumors at the time of aspiration and allow a definitive diagnosis.
  • On fine needle aspiration, the patient was diagnosed as having a benign skin adnexal tumor.
  • RESULTS: The cytologic features of trichoblastoma resembled a cellular fibroadenoma/phyllodes tumor on aspiration, not previously described in the literature.
  • If the cytomorphology of a skin or subcutaneous aspirate appears to resemble that of a fibroadenoma, the diagnosis of a trichoblastoma should be entertained.
  • Peripheral palisading of nuclei at the edges of the basaloid cell sheets and squamous eddy formation are clues to the diagnosis but may be very focal and could be overlooked.
  • If the tumor occurs in the region of the breast, distinction from a fibroadenoma would be difficult if these additional features were not prominent.
  • CONCLUSION: Knowledge of the cytologic features of trichoblastoma will allow correct management of the patient and prevent misdiagnosis as other benign or malignant tumors.

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  • (PMID = 20014558.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Schulman FY, Johnson TO, Facemire PR, Fanburg-Smith JC: Feline peripheral nerve sheath tumors: histologic, immunohistochemical, and clinicopathologic correlation (59 tumors in 53 cats). Vet Pathol; 2009 Nov;46(6):1166-80
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  • [Title] Feline peripheral nerve sheath tumors: histologic, immunohistochemical, and clinicopathologic correlation (59 tumors in 53 cats).
  • Feline peripheral nerve sheath tumors are uncommonly reported, and their clinical behavior has not been well documented.
  • Fifty-nine peripheral nerve sheath tumors were collected from 53 cats.
  • All of the tumors involved skin, subcutis, skeletal muscle, and/or mucous membranes.
  • Histologically, the tumors were composed of compact to loosely arranged streams and fascicles of spindled cells with eosinophilic, often wavy cytoplasmic processes; small to occasionally moderate amounts of collagenous to myxoid matrix; and nuclear palisading.
  • Immunohistochemically, all tumors were positive for vimentin and S-100 protein, 44 of 59 were positive for glial fibrillary acidic protein (GFAP), and all were negative for muscle specific actin.
  • The tumors fell into 3 histologic categories: 34 benign tumors with Antoni A areas that were S-100 protein and GFAP positive, 9 benign tumors that lacked Antoni A areas and were S-100 protein positive and GFAP negative, and 16 tumors with features of malignancy.
  • Recurrent tumors were submitted or tumors were reported to have recurred in 9 cases.
  • Tumor recurrence was reported for all 3 of the histologic subtypes.
  • [MeSH-major] Cat Diseases / pathology. Nerve Sheath Neoplasms / veterinary

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  • (PMID = 19605904.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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59. Fleming DM, Cross KW, Barley MA: Recent changes in the prevalence of diseases presenting for health care. Br J Gen Pract; 2005 Aug;55(517):589-95
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  • Age-standardised prevalence rates per 10,000 registered persons and 99% confidence intervals (CIs) were calculated using the national census population for 2001 as the standard.
  • Survey differences in prevalence were identified from non-overlapping CIs.
  • The prevalence of mental disorders, skin disease and musculoskeletal disorders showed little change.
  • Particular increases were noted for other malignant and benign neoplasms of the skin, hypothyroidism and diabetes.

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  • [Cites] BMJ. 2003 Jun 28;326(7404):1439-43 [12829558.001]
  • [Cites] BMJ. 2002 Dec 14;325(7377):1397-8 [12480857.001]
  • [Cites] Arch Dis Child. 2004 Mar;89(3):282-5 [14977715.001]
  • [Cites] Eur J Public Health. 2004 Mar;14(1):10-4 [15080383.001]
  • [Cites] J Epidemiol Community Health. 1991 Sep;45(3):180-3 [1757757.001]
  • [Cites] BMJ. 1998 May 23;316(7144):1572-6 [9596597.001]
  • [Cites] Commun Dis Rep CDR Suppl. 1998 Dec;8(7):S1-11 [9879128.001]
  • [Cites] Commun Dis Public Health. 1999 Jun;2(2):96-100 [10402742.001]
  • [Cites] Diabetologia. 1999 Jul;42(7):793-801 [10440120.001]
  • [Cites] Eur J Epidemiol. 1999 May;15(5):467-73 [10442473.001]
  • [Cites] Br J Gen Pract. 2003 Oct;53(495):778-83 [14601353.001]
  • [Cites] Thorax. 2000 Aug;55(8):662-5 [10899242.001]
  • [Cites] Commun Dis Public Health. 2000 Sep;3(3):213-5 [11014039.001]
  • [Cites] Diabet Med. 2001 Feb;18(2):126-32 [11251676.001]
  • [Cites] N Engl J Med. 2001 May 3;344(18):1343-50 [11333990.001]
  • [Cites] Br J Gen Pract. 2001 Aug;51(469):638-43 [11510393.001]
  • [CommentIn] Br J Gen Pract. 2005 Nov;55(520):884 [16282011.001]
  • (PMID = 16105366.001).
  • [ISSN] 0960-1643
  • [Journal-full-title] The British journal of general practice : the journal of the Royal College of General Practitioners
  • [ISO-abbreviation] Br J Gen Pract
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1463227
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60. Busam KJ: Cutaneous desmoplastic melanoma. Adv Anat Pathol; 2005 Mar;12(2):92-102
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  • [Title] Cutaneous desmoplastic melanoma.
  • It most often presents as an indurated lesion in chronically sun-damaged skin.
  • At the time of excision, the tumors usually extend into the reticular dermis or deeper.
  • It may simulate histologically sclerosing melanocytic nevi as well as various benign and malignant nonmelanocytic lesions.
  • There is significant morphologic variability among tumors classified as DM.
  • Desmoplasia may be prominent throughout the entire tumor ("pure" DM) or represent a portion of an otherwise nondesmoplastic melanoma ("combined" DM).
  • Some tumors show neuroma-like features with prominent nerve involvement, in which case the term "desmoplastic neurotropic melanoma" is used.
  • Evidence is also emerging that for patients with thick melanomas, the presence of a paucicellular fibrosing tumor histology (pure DM) is a favorable prognostic factor for survival.
  • [MeSH-major] Melanoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Fibrosis. Humans. Neoplasm Recurrence, Local. Nevus, Pigmented / diagnosis. S100 Proteins / analysis. Sunlight / adverse effects

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  • (PMID = 15731577.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
  • [Number-of-references] 56
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61. Villanueva J, González A, Cornejo M, Núñez C, Encina S: Osteochondroma of the coronoid process. Med Oral Patol Oral Cir Bucal; 2006 May;11(3):E289-91
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  • Osteochondroma is the most common benign neoplasia of the skeleton.
  • We present a review of the literature and the report of the cas of a 44 years old female patient presenting limited mouth opening and swelling of the left cheek, with diffuse limits, bony consistency, painless, and covered of normal skin.
  • In panoramic radiographs was evident a coronoid tumor localized in the union of zigomatic arch and bone.
  • The histopatological diagnosis was osteochondroma.
  • Clinical and pathological aspects, treatment and differential diagnosis with other lesions are discussed.
  • [MeSH-major] Mandibular Neoplasms. Osteochondroma

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  • (PMID = 16648770.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 13
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62. Yeh AH, Bohula EA, Macaulay VM: Human melanoma cells expressing V600E B-RAF are susceptible to IGF1R targeting by small interfering RNAs. Oncogene; 2006 Oct 26;25(50):6574-81
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  • The type 1 insulin-like growth factor receptor (IGF1R) is overexpressed by malignant melanomas compared with benign naevi, and mediates proliferation, motility and protection from apoptosis.
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Cell Survival. Drug Resistance, Neoplasm. Extracellular Signal-Regulated MAP Kinases / metabolism. Gene Silencing. Humans. Melanocytes / metabolism. Point Mutation. Proto-Oncogene Proteins c-akt / metabolism. Proto-Oncogene Proteins p21(ras) / metabolism. Signal Transduction. Skin Neoplasms / genetics. Skin Neoplasms / metabolism. Transfection. Tumor Cells, Cultured


63. Izumi M, Ohara K, Hoashi T, Nakayama H, Chiu CS, Nagai T, Matsubayashi J, Iwaya K, Mukai K: Subungual melanoma: histological examination of 50 cases from early stage to bone invasion. J Dermatol; 2008 Nov;35(11):695-703
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  • It is extremely difficult to differentiate it histologically from benign melanonychia striata or melanocytic nevus, especially in the early stage.
  • From these observations, we would like to propose three new pathological clues of early stage subungual melanoma: (i) "skip lesion", proliferation of the tumor cells are more prominent in the hyponychium than in the nail bed or nail matrix;.
  • [MeSH-major] Melanoma / pathology. Nail Diseases / pathology. Nails / pathology. Skin / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Bone Neoplasms / secondary. Disease Progression. Humans. Retrospective Studies

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  • (PMID = 19120763.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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64. Schmid-Wendtner MH, Burgdorf W: Ultrasound scanning in dermatology. Arch Dermatol; 2005 Feb;141(2):217-24
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  • The best established is 20-MHz scanning, which can be used to measure tumor thickness and/or skin thickness when treating inflammatory diseases such as scleroderma or psoriasis.
  • Real-time sonography with 7.5- to 10-MHz probes has assumed an increasingly important role, since it is used to search for and image lymph nodes and subcutaneous tumors in a variety of clinical settings, including preoperative staging and follow-up of melanoma.
  • Ultrasonography is capable of revealing the 3-dimensional size and outline of subcutaneous lesions, for example, lymph nodes, subcutaneous tumor masses or hematomas, and their relation to adjacent vessels.
  • All this information can be combined to help distinguish between benign and malignant lymphadenopathy and to determine the malignant potential of a subcutaneous lesion.
  • [MeSH-major] Melanoma / ultrasonography. Skin Neoplasms / ultrasonography. Ultrasonography, Doppler, Color
  • [MeSH-minor] Dermatology / instrumentation. Dermatology / methods. Disease Progression. Female. Humans. Male. Monitoring, Physiologic. Neoplasm Staging. Prognosis. Sensitivity and Specificity

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  • (PMID = 15724019.001).
  • [ISSN] 0003-987X
  • [Journal-full-title] Archives of dermatology
  • [ISO-abbreviation] Arch Dermatol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 30
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65. Cho KE, Son EJ, Kim JA, Youk JH, Kim EK, Kwak JY, Jeong J: Clear cell hidradenoma of the axilla: a case report with literature review. Korean J Radiol; 2010 Jul-Aug;11(4):490-2
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  • Clear cell hidradenoma is an uncommon benign skin appendageal tumor that typically involves the dermal layer of the head, face, and extremities.
  • The breast is a rare site for this lesion, with only two documented cases, which were determined based on mammogram and sonogram findings.
  • [MeSH-major] Adenoma, Sweat Gland / radiography. Adenoma, Sweat Gland / ultrasonography. Axilla. Sweat Gland Neoplasms / radiography. Sweat Gland Neoplasms / ultrasonography
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Female. Humans. Mammography. Middle Aged. Ultrasonography, Doppler

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  • [Cites] Br J Radiol. 2007 Jan;80(949):e27-9 [17267467.001]
  • [Cites] Breast Cancer. 2007;14(3):307-11 [17690510.001]
  • [Cites] Skeletal Radiol. 2007 Dec;36(12):1185-90 [17624528.001]
  • [Cites] Clin Radiol. 2004 Dec;59(12):1142-4 [15556599.001]
  • [Cites] Int J Gynecol Pathol. 2008 Jul;27(3):457-60 [18580328.001]
  • [Cites] J Am Acad Dermatol. 1985 Jan;12(1 Pt 1):15-20 [2984259.001]
  • [Cites] J Cutan Pathol. 1988 Aug;15(4):226-9 [2846662.001]
  • [Cites] J Ultrasound Med. 2008 May;27(5):813-8 [18424661.001]
  • (PMID = 20592936.001).
  • [ISSN] 2005-8330
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2893323
  • [Keywords] NOTNLM ; Axilla mass / Hidradenoma / Ultrasonography
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66. Kazikdas KC, Onal K, Kuehnel TS, Ozturk T: An intradermal nevus of the external auditory meatus. Eur Arch Otorhinolaryngol; 2006 Mar;263(3):253-5
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  • Upon excisional biopsy, the tumor was diagnosed as an intradermal nevus.
  • The possibility of a benign nevomelanocytic nevus should not be underestimated when evaluating a lesion obstructing the ear canal, and all melanocytic nevi should be excised instead of biopsied to rule out melanoma.
  • [MeSH-major] Ear Canal. Nevus, Intradermal / diagnosis. Skin Neoplasms / diagnosis

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  • [Cites] Acta Otorhinolaryngol Belg. 1998;52(1):29-36 [9581194.001]
  • [Cites] Nihon Jibiinkoka Gakkai Kaiho. 1982 Sep 20;85(9):1039-46 [7175597.001]
  • [Cites] Ear Nose Throat J. 2003 Jan;82(1):38-41 [12610902.001]
  • [Cites] AMA Arch Derm. 1955 Aug;72(2):120-32 [14397843.001]
  • [Cites] Jibiinkoka. 1966 May;38(5):493-6 [6006879.001]
  • [Cites] Laryngoscope. 1998 Apr;108(4 Pt 1):620-3 [9546281.001]
  • [Cites] Auris Nasus Larynx. 2003 Aug;30(3):287-90 [12927294.001]
  • [Cites] Dermatology. 1998;196(4):425-6 [9669120.001]
  • [Cites] Auris Nasus Larynx. 2004 Mar;31(1):65-7 [15041056.001]
  • [Cites] J Otolaryngol. 1988 Aug;17(5):241-3 [3216448.001]
  • (PMID = 16012861.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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67. Wong RP, Khosravi S, Martinka M, Li G: Myeloid leukemia-1 expression in benign and malignant melanocytic lesions. Oncol Rep; 2008 Apr;19(4):933-7
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  • [Title] Myeloid leukemia-1 expression in benign and malignant melanocytic lesions.
  • Myeloid leukemia-1 (Mcl-1) is an anti-apoptotic protein implicated in tumor progression.
  • Its expression was found to be elevated in many types of human cancers and is correlated with tumor progression.
  • [MeSH-major] Dysplastic Nevus Syndrome / metabolism. Melanoma / chemistry. Neoplasm Proteins / analysis. Nevus / chemistry. Proto-Oncogene Proteins c-bcl-2 / analysis

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  • (PMID = 18357378.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Myeloid Cell Leukemia Sequence 1 Protein; 0 / Neoplasm Proteins; 0 / Proto-Oncogene Proteins c-bcl-2
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68. Mourmouras V, Cevenini G, Cosci E, Epistolato MC, Biagioli M, Barbagli L, Luzi P, Mannucci S, Miracco C: Nucleolin protein expression in cutaneous melanocytic lesions. J Cutan Pathol; 2009 Jun;36(6):637-46
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  • [Title] Nucleolin protein expression in cutaneous melanocytic lesions.
  • We aimed at exploring this protein and its prognostic impact in cutaneous melanocytic lesions.
  • METHODS: We studied 193 cases including benign, dysplastic and malignant melanocytic lesions.
  • The patterns CNpl+ and/or ID+CNpl+ were never observed in benign lesions, in which ID+ were also virtually absent.
  • [MeSH-major] Melanoma / metabolism. Melanoma / pathology. Phosphoproteins / biosynthesis. RNA-Binding Proteins / biosynthesis. Skin Neoplasms / metabolism. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Cell Nucleus / metabolism. Disease Progression. Dysplastic Nevus Syndrome / metabolism. Dysplastic Nevus Syndrome / pathology. Humans. Image Interpretation, Computer-Assisted. Immunohistochemistry. Kaplan-Meier Estimate. Precancerous Conditions / pathology. Prognosis

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  • (PMID = 19515042.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Phosphoproteins; 0 / RNA-Binding Proteins; 0 / nucleolin
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69. Gómez de la Fuente E, Sols M, Pinedo F, Alvarez-Fernández JG, Vicente FJ, Naz E, López-Estebaranz JL: [Atypical fibroxanthoma. Clinical/pathological study of 10 cases]. Actas Dermosifiliogr; 2005 Apr;96(3):153-8
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  • [Transliterated title] Fibroxantoma atípico. Estudio clinicopatológico de 10 casos.
  • INTRODUCTION: Atypical fibroxanthoma (AFX) is a rare tumor of unknown histogenesis, considered by most authorities as a superficial form of malignant fibrous histiocytoma (MFH).
  • Clinical (age, onset-diagnosis time, location, accompanying pathology, outcome), histological (architectural pattern, cell type, ulceration, vascular or perineural invasion, subcutis involvement, pleomorphism, mitosis, inflammatory infiltrate) and immunohistochemical variable were analyzed.
  • CASES REPORT: Clinical and epidemiological features coincide with those previously reported: onset late in life, short time onset-diagnosis, involvement of skin with notable sun damage and a good outcome.
  • DISCUSSION: The diagnosis of AXF is always of exclusion.
  • Other spindle-cell tumors such as squamous cell carcinoma, malignant melanoma, leyomiosarcoma or dermatofibrosarcoma protuberans must be ruled out by immunohistochemical techniques.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology

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  • (PMID = 16476356.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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70. Carlsten JR, Lewis MD, Saddler K, Reilly P, Pan T, Gnepp DR, Robinson-Bostom L: Spiradenocylindrocarcinoma: a malignant hybrid tumor. J Cutan Pathol; 2005 Feb;32(2):166-71
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  • [Title] Spiradenocylindrocarcinoma: a malignant hybrid tumor.
  • BACKGROUND: Eccrine spiradenomas and cylindromas are benign, slowly growing, cutaneous adnexal neoplasms, recently hypothesized to arise from a common pluripotential cell; malignant variants are rare.
  • Benign tumors demonstrating both spiradenomatous and cylindromatous features have been infrequently reported.
  • Recent immunohistochemical studies of these two tumors have provided compelling evidence that these two tumors may merely represent a single tumor type with a spectrum of histological features.
  • CASE REPORT: We describe two cases of a malignant variant of this rare hybrid tumor occurring in a 62-year-old male and a 72-year-old female.
  • CONCLUSION: We propose the term 'spiradenocylindrocarcinoma' to describe malignant tumors with features of both a spiradenoma and a cylindroma.
  • In conjunction with histological features of malignancy, p53 and Ki-67 immunohistochemical staining may provide helpful clues in determining the malignant potential of this tumor.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Carcinoma, Adenoid Cystic / pathology. Neoplasms, Multiple Primary / pathology. Skin Neoplasms / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Aged. Female. Gastrointestinal Neoplasms / secondary. Humans. Immunohistochemistry. Male. Middle Aged

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  • [ErratumIn] J Cutan Pathol. 2005 Jul;32(6):453
  • (PMID = 15606677.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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71. Stefanato CM, Robson A, Calonje JE: The histopathologic spectrum of regression in atypical fibroxanthoma. J Cutan Pathol; 2010 Mar;37(3):310-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Atypical fibroxanthoma (AFX) with prominent fibrosis, sclerosis and hyalinization, and near-total tumor regression is rare.
  • METHODS: Eight cases of AFX presenting with fibrosis were reviewed as to their tumor architecture, the degree and pattern of fibrosis and the associated inflammatory cell infiltrate.
  • Advanced fibrosis (6/8 cases) was associated with lamellar sclerosis, keloidal features, hyalinization and with near-total tumor replacement.
  • Prominent fibrosis rimming the periphery was present in all tumors.
  • CONCLUSIONS: Fibrosis with prominent sclerosis and hyalinization replacing the tumor is rare in AFX.
  • [MeSH-major] Head and Neck Neoplasms / pathology. Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Xanthomatosis / pathology


72. Mindea SA, Kaplan KJ, Howard MA, O'Leary ST: Granular cell tumor involving the axillary nerve: an unusual occurrence. Case report. Neurosurg Focus; 2007;22(6):E24
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  • [Title] Granular cell tumor involving the axillary nerve: an unusual occurrence. Case report.
  • Granular cell tumors (GCTs) are benign lesions that, paradoxically, despite originating from the Schwann cell, are most commonly seen in nonneuronal tissue including the skin, subcutaneous tissue, and tongue.
  • [MeSH-major] Axilla / innervation. Granular Cell Tumor / diagnosis. Peripheral Nervous System Neoplasms / diagnosis. Peripheral Nervous System Neoplasms / radiography

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  • (PMID = 17613216.001).
  • [ISSN] 1092-0684
  • [Journal-full-title] Neurosurgical focus
  • [ISO-abbreviation] Neurosurg Focus
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Cobellis L, Pecori E, Rigatti F, Scaffa C, Rotondi M, Messalli EM: A rare case of female pelvic mass: angioleiomyoma of the broad ligament. Eur J Gynaecol Oncol; 2007;28(5):418-20
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  • Angioleiomyoma is a benign mesenchymal neoplasm composed of smooth muscle cells and thick-walled vessels.
  • It is usually found in the skin of the lower extremities.
  • Angioleiomyoma is a very rare tumor among the ever-expanding repertoire of growth variants described in benign uterine leiomyoma.
  • More rare is a solitary tumor of the broad ligament.
  • Thus angioleiomyoma of the broad ligament is an extremely rare benign tumor of the female pelvis.
  • The site of the benign mass was the left broad ligament of the uterus.
  • On pathologic examination of the specimen, the tumor was diagnosed as angioleiomyoma.
  • We present a case of angioleiomyoma of the broad ligament because of its extreme rarity and the large size of the tumor.

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  • (PMID = 17966227.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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74. Liegl B, Hornick JL, Fletcher CD: Primary cutaneous PEComa: distinctive clear cell lesions of skin. Am J Surg Pathol; 2008 Apr;32(4):608-14
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  • [Title] Primary cutaneous PEComa: distinctive clear cell lesions of skin.
  • PEComas arising in somatic soft tissue or skin are rare.
  • To further characterize the clinicopathologic spectrum, we herein report a series of 10 primary cutaneous PEComas.
  • Tumor size ranged from 0.7 to 2 cm (median size, 1.5 cm).
  • Eight tumors were located on the limbs and 2 on the back.
  • The tumors involved the dermis and commonly showed infiltration into the subcutaneous fat.
  • Six tumors were composed of epithelioid cells and 4 showed mixed epithelioid and spindle cell morphology.
  • Tumor cells had clear, palely eosinophilic or granular cytoplasm.
  • Multinucleate tumor giant cells were observed in 3 cases.
  • In cases where HMB-45 was positive in fewer than 5% of tumor cells (5/10), microphthalmia transcription factor was positive in the majority of the tumor cell nuclei.
  • Primary cutaneous PEComas are rare and thus far apparently benign cutaneous tumors.
  • Accurate recognition of this entity is essential because of potential misdiagnosis as malignant tumors, especially malignant melanoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Melanoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / analysis. Adolescent. Adult. Aged. Aged, 80 and over. Antigens, Neoplasm / analysis. Calcium-Binding Proteins / analysis. Calmodulin-Binding Proteins / analysis. Dermis / pathology. Desmin / analysis. Diagnosis, Differential. Female. Giant Cells / pathology. Humans. Immunohistochemistry. Keratins / analysis. MART-1 Antigen. Male. Melanoma-Specific Antigens. Microfilament Proteins / analysis. Microphthalmia-Associated Transcription Factor / analysis. Middle Aged. Mitotic Index. Mucin-1 / analysis. Neoplasm Invasiveness. Neoplasm Proteins / analysis. Subcutaneous Fat / pathology

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  • [CommentIn] Am J Dermatopathol. 2016 Feb;38(2):165-6 [26825164.001]
  • (PMID = 18277881.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Calcium-Binding Proteins; 0 / Calmodulin-Binding Proteins; 0 / Desmin; 0 / MART-1 Antigen; 0 / MITF protein, human; 0 / MLANA protein, human; 0 / Melanoma-Specific Antigens; 0 / Microfilament Proteins; 0 / Microphthalmia-Associated Transcription Factor; 0 / Mucin-1; 0 / Neoplasm Proteins; 0 / calponin; 68238-35-7 / Keratins
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75. Fulkerson DH, Luerssen TG, Hattab EM, Kim DL, Smith JL: Long-term follow-up of solitary intracerebral juvenile xanthogranuloma. Case report and review of the literature. Pediatr Neurosurg; 2008;44(6):480-5
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  • Juvenile xanthogranuloma is a benign, non-Langerhans-cell histiocytic infiltrate that typically presents as a solitary cutaneous lesion in childhood.
  • There are reports of extracutanous involvement, including tumors in the central nervous system.
  • A solitary, intraparenchymal tumor without skin manifestations is a rare event, with only 3 prior cases reported in the literature.
  • Considering the rarity of this tumor, it is unclear whether patients need adjuvant therapy after excision of a solitary intraparenchymal tumor.
  • [MeSH-major] Brain Diseases / diagnosis. Brain Diseases / surgery. Xanthogranuloma, Juvenile / diagnosis. Xanthogranuloma, Juvenile / surgery


76. Lucas A, Betlloch I, Planelles M, Martínez T, Pérez-Crespo M, Mataix J, Belinchón I: Non-melanocytic benign skin tumors in children. Am J Clin Dermatol; 2007;8(6):365-9
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  • [Title] Non-melanocytic benign skin tumors in children.
  • BACKGROUND: Dermatologists often attend children with benign skin tumors and cysts.
  • The decision to perform dermatologic surgery in children may be difficult to make, especially in cases of benign tumors.
  • OBJECTIVE: The objective of this study was to determine the nature of non-melanocytic benign skin tumors amenable to dermatologic surgery in children.
  • METHODS: Histopathologic studies of skin tumors in children treated by our department between January 2004 and December 2005 were studied.
  • Malignant and melanocytic tumors were excluded.
  • Age, sex, type of tumor, diagnostic category, site, size, reason for removal, type of anesthesia, and any other associated disorders were recorded.
  • RESULTS: The records revealed that 121 patients presented 129 non-melanocytic benign skin tumors (73 in boys and 56 in girls).
  • Tumors were located on the head and neck (45.7%), trunk (34.1%), and limbs (20.1%).
  • The reasons that led to removal of the tumors were: increase in the size of the tumor (49%); various types of discomfort, such as severe itching or pain (30%); parental concern (4%); diagnostic uncertainty (16%); and esthetic reasons (1%).
  • CONCLUSION: There is a wide diversity of non-melanocytic benign skin tumors in children, some of which require surgical treatment.
  • Pilomatrixomas appear to be the most frequent benign tumors; there are also high frequencies of infundibular cysts, pyogenic granulomas, and viral tumors.
  • [MeSH-major] Skin Neoplasms / pathology

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  • (PMID = 18039019.001).
  • [ISSN] 1175-0561
  • [Journal-full-title] American journal of clinical dermatology
  • [ISO-abbreviation] Am J Clin Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
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77. Takami HE, Ikeda Y: Minimally invasive thyroidectomy. Curr Opin Oncol; 2006 Jan;18(1):43-7
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  • PURPOSE OF REVIEW: Based on recent advances in ultrasonography, color-Doppler sonography and ultrasound-guided fine needle aspiration biopsy, minimally invasive thyroidectomy has been widely employed for treating thyroid tumors.
  • Our procedure differs from conventional thyroidectomy in requiring a 3-cm skin incision, and in not raising of a skin flap and not dissecting the sternohyoid muscle.
  • The present indications for this procedure include benign follicular adenomas less than 4 cm in diameter, low-risk papillary carcinomas less than 10 mm, oxyphilic cell tumors less than 4 cm and Graves' disease as imaged on preoperative ultrasonography.
  • Total thyroidectomy and bilateral modified neck dissection is possible, if the tumor is not large.
  • [MeSH-major] Thyroid Neoplasms / surgery. Thyroidectomy / methods. Ultrasonography, Interventional / methods. Video-Assisted Surgery / methods

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  • (PMID = 16357563.001).
  • [ISSN] 1040-8746
  • [Journal-full-title] Current opinion in oncology
  • [ISO-abbreviation] Curr Opin Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 3K9958V90M / Ethanol
  • [Number-of-references] 17
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78. Beer TW, Drury P, Heenan PJ: Atypical fibroxanthoma: a histological and immunohistochemical review of 171 cases. Am J Dermatopathol; 2010 Aug;32(6):533-40
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  • Patients were aged between 41 and 97 years (median age 74), with 76% of tumors occurring in men (male to female ratio approximately 3 to 1).
  • Most tumors were small, with a median diameter of 10 mm and a range of 4-35 mm.
  • Bland cytological appearances (spindle cell nonpleomorphic AFX) were noted in 5 tumors, with osteoclast-like giant cells in 2.
  • No tumors expressed melanocytic or epithelial markers.
  • In conclusion, AFX may show a wide range of histological appearances, and a panel of immunohistochemical markers is essential to make the correct diagnosis.
  • Specific diagnosis is important because there seems to be a very low risk of recurrence or metastasis despite the frequently alarming histology.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged


79. Kwak JY, Kim EK, Chung SY, You JK, Oh KK, Lee YH, Kwon TH, Jung HK: Unilateral breast edema: spectrum of etiologies and imaging appearances. Yonsei Med J; 2005 Feb 28;46(1):1-7
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  • Breast edema is defined as a mammographic pattern of skin thickening, increased parenchymal density, and interstitial marking.
  • It can be caused by benign or malignant diseases, as a result of a tumor in the dermal lymphatics of the breast, lymphatic congestion caused by breast, lymphatic drainage obstruction, or by congestive heart failure.

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  • [Cites] Australas Radiol. 2000 May;44(2):234-6 [10849995.001]
  • [Cites] Eur J Radiol. 1997 Feb;24(2):124-30 [9097054.001]
  • [Cites] Yonsei Med J. 2001 Oct;42(5):497-502 [11675677.001]
  • [Cites] Cancer. 1972 Jun;29(6):1691-6 [4337956.001]
  • [Cites] Cancer. 1974 Apr;33(4):1045-7 [4819210.001]
  • [Cites] Radiology. 1976 Mar;118(3):587-9 [1251007.001]
  • [Cites] Ann Surg. 1981 Dec;194(6):749-53 [7305490.001]
  • [Cites] Cancer. 1982 Jun 1;49(11):2295-9 [7074546.001]
  • [Cites] Radiol Clin North Am. 1982 Sep;20(3):561-8 [7111707.001]
  • [Cites] Radiology. 1987 Aug;164(2):455-61 [3037592.001]
  • [Cites] Practitioner. 1989 Nov 8;233(1478):1436, 1439 [2616518.001]
  • [Cites] Australas Radiol. 1991 Aug;35(3):274-5 [1763994.001]
  • [Cites] Radiol Clin North Am. 1992 Jan;30(1):107-38 [1732922.001]
  • [Cites] Am Surg. 1992 Dec;58(12):792-6 [1456611.001]
  • [Cites] Nephron. 1993;63(3):351-3 [8446276.001]
  • [Cites] Radiology. 1994 Mar;190(3):831-4 [8115635.001]
  • [Cites] Radiology. 1994 Jul;192(1):157-60 [8208929.001]
  • [Cites] Invest Radiol. 1995 Oct;30(10):582-7 [8557497.001]
  • [Cites] Clin Radiol. 1996 May;51(5):354-8 [8641100.001]
  • [Cites] Eur Radiol. 2001;11(9):1659-65 [11511887.001]
  • (PMID = 15744799.001).
  • [ISSN] 0513-5796
  • [Journal-full-title] Yonsei medical journal
  • [ISO-abbreviation] Yonsei Med. J.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Korea (South)
  • [Number-of-references] 23
  • [Other-IDs] NLM/ PMC2823034
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80. Tokyol C, Aktepe F, Yavas BD, Yildiz H, Aycicek A: Chondroid syringoma: a case report. Acta Cytol; 2010 Sep-Oct;54(5 Suppl):973-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Chondroid syringoma is a benign skin adnexal tumor.
  • The reported incidence of chondroid syringoma among primary skin tumors is low and has been reported at 0.01-0.098%.
  • A diagnosis of benign appendageal tumor of the skin was made.
  • Surgical excision of tumor was done.
  • CONCLUSION: Chondroid syringoma should be included in the differential diagnosis of a slowly growing nodule on the head or neck.
  • The diagnosis can be confirmed by means of fine needle aspiration cytology.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Lip Neoplasms / pathology

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  • (PMID = 21053580.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Chwirot BW, Kuźbicki Ł: Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours. Melanoma Res; 2007 Jun;17(3):139-45
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  • [Title] Cyclooxygenase-2 (COX-2): first immunohistochemical marker distinguishing early cutaneous melanomas from benign melanocytic skin tumours.
  • In this study, we investigated whether the COX-2 expression level might be a useful immunohistochemical marker for distinguishing cutaneous melanomas from benign melanocytic lesions.
  • Up to now, immunohistochemical markers have not ensured satisfactory sensitivity and specificity of differential pathologic diagnosis of melanoma.
  • In conclusion, COX-2 is the first immunohistochemical marker that allows the distinguishing of early melanomas from benign melanocytic lesions with both high sensitivity and specificity.
  • [MeSH-major] Biomarkers, Tumor / analysis. Cyclooxygenase 2 / analysis. Immunohistochemistry. Melanoma / diagnosis. Membrane Proteins / analysis. Nevus, Pigmented / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Algorithms. Diagnosis, Differential. Humans. Melanocytes / enzymology. Melanocytes / pathology. Neoplasm Staging. Predictive Value of Tests. ROC Curve. Sensitivity and Specificity

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  • (PMID = 17505259.001).
  • [ISSN] 0960-8931
  • [Journal-full-title] Melanoma research
  • [ISO-abbreviation] Melanoma Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Membrane Proteins; EC 1.14.99.1 / Cyclooxygenase 2; EC 1.14.99.1 / PTGS2 protein, human
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82. Frydman AF, Mercer SE, Kleinerman R, Yanofsky VR, Birge MB: Acquired fibrokeratoma presenting as multiple plantar nodules. Dermatol Online J; 2010;16(10):5
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  • Acquired digital fibrokeratoma is a rare benign fibroepithelial tumor that typically presents as a solitary asymptomatic nodule on the finger or toe.
  • [MeSH-major] Foot Dermatoses / pathology. Keratosis / pathology. Skin Neoplasms / pathology

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  • (PMID = 21062599.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Zhou Y, Dai DL, Martinka M, Su M, Zhang Y, Campos EI, Dorocicz I, Tang L, Huntsman D, Nelson C, Ho V, Li G: Osteopontin expression correlates with melanoma invasion. J Invest Dermatol; 2005 May;124(5):1044-52
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  • In order to uncover genes unique to melanoma cells, we used high-density DNA microarrays to examine the gene expression profiles of metastatic melanoma nodules using benign nevi as controls.
  • Immunohistochemistry staining on tissue microarrays and individual skin biopsies representing different stages of melanoma progression revealed that OPN expression is first acquired at the step of melanoma tissue invasion.
  • Our observations suggest that OPN may be acquired early in melanoma development and progression, and may enhance tumor cell growth in invasive melanoma.
  • [MeSH-minor] Adult. Aged. Cell Line, Tumor. Cell Proliferation. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Invasiveness. Oligonucleotide Array Sequence Analysis. Osteopontin. RNA, Messenger / analysis. RNA, Small Interfering / pharmacology

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  • [CommentIn] J Invest Dermatol. 2005 May;124(5):xiv-xv [15854021.001]
  • [CommentIn] J Invest Dermatol. 2005 May;124(5):xvi-xviii [15854023.001]
  • [CommentIn] J Invest Dermatol. 2005 May;124(5):xix-xx [15854022.001]
  • (PMID = 15854047.001).
  • [ISSN] 0022-202X
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / RNA, Messenger; 0 / RNA, Small Interfering; 0 / SPP1 protein, human; 0 / Sialoglycoproteins; 106441-73-0 / Osteopontin
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84. Reuhl J, Fink T, Glees M, Bernd L, Fisseler-Eckhoff A: [An unusual complication after an insect bite? Diagnostic procedures in a case of granular cell tumor]. Pathologe; 2007 Jul;28(4):273-7
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  • [Title] [An unusual complication after an insect bite? Diagnostic procedures in a case of granular cell tumor].
  • Granular cell tumors are, in almost all cases, benign soft tissue tumors, although malignant variants have rarely been described in a variety of anatomical locations.
  • In the case presented here, a so-called atypical granular cell tumor was diagnosed based on two criteria, being differentiated from the usual histological findings by enhanced mitotic activity and focal spindle cell proliferation.
  • Further suspicious characters of the tumor were its size of 13x10x5 cm on MRT as well as its long-term clinical course (1.5 years).
  • The diagnostic procedures undergone until resection of the tumor, including the macroscopic and histological findings, are presented.
  • The diagnosis can be made with certainty by using conventional histology in combination with immunohistochemistry.
  • The tumor cells react positively with antibodies against S-100 protein, NSE, laminin, myelin proteins and myelin-associated glycoproteins.
  • These staining patterns underscore the neural origin of the tumor tissue.
  • In this case a mitotic frequency of two per ten high power fields and focal spindle cells led to the diagnosis of an atypical granular cell tumor, whereas the criteria for a malignant variant were not met.
  • [MeSH-major] Bites and Stings / complications. Bites and Stings / pathology. Granular Cell Tumor / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Animals. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. Mitosis

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  • [Cites] Hum Pathol. 1996 Aug;27(8):853-8 [8760023.001]
  • [Cites] Ultrastruct Pathol. 1988 Jan-Feb;12(1):137-44 [2832989.001]
  • [Cites] Am J Surg Pathol. 1991 May;15(5):460-5 [1852131.001]
  • [Cites] Cancer. 1984 Feb 1;53(3):524-9 [6692257.001]
  • [Cites] Ann Surg. 1945 Mar;121(3):361-72 [17858577.001]
  • [Cites] Am J Surg Pathol. 1998 Jul;22(7):779-94 [9669341.001]
  • [Cites] Am J Clin Pathol. 1969 Aug;52(2):208-11 [4307918.001]
  • [Cites] Am J Surg Pathol. 1981 Jan;5(1):37-46 [6264813.001]
  • [Cites] Histopathology. 1989 Apr;14(4):417-9 [2544502.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;420(3):219-26 [1372779.001]
  • [Cites] Cancer. 1987 Jul 15;60(2):220-2 [3594359.001]
  • [Cites] Am J Surg Pathol. 2005 Jul;29(7):927-34 [15958858.001]
  • (PMID = 16555043.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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85. El Ibrahimi A, Daoudi A, Znati K, Elmrini A, Boutayeb F: [Insulated leg pilomatrixoma: a rare localization]. Ann Chir Plast Esthet; 2009 Aug;54(4):388-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Pilomatricome isolé de la jambe. Une rare localisation.
  • Pilomatrixoma is a benign skin neoplasm of the hair follicle.
  • It's usually misdiagnosed and confused with other skin lesions.
  • [MeSH-major] Hair Diseases. Leg. Pilomatrixoma. Skin Neoplasms

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  • (PMID = 19195758.001).
  • [ISSN] 1768-319X
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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86. Matcham NJ, Andronikou S, Sibson K, Ramani P, Grier D: Systemic juvenile xanthogranulomatosis imitating a malignant abdominal wall tumor with lung metastases. J Pediatr Hematol Oncol; 2007 Jan;29(1):72-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Systemic juvenile xanthogranulomatosis imitating a malignant abdominal wall tumor with lung metastases.
  • Juvenile xanthogranulomatosis (JXG) is a rare benign condition, which usually presents with characteristic skin lesions and can be diagnosed clinically.
  • In particular, systemic disease presenting without skin lesions is unusual.
  • [MeSH-major] Abdominal Neoplasms / radiography. Abdominal Wall. Lung Neoplasms / radiography. Tomography Scanners, X-Ray Computed. Xanthogranuloma, Juvenile / radiography
  • [MeSH-minor] Child, Preschool. False Positive Reactions. Female. Humans. Neoplasm Metastasis. Sarcoma / radiography

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  • (PMID = 17230073.001).
  • [ISSN] 1077-4114
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. Yildiz B, Ozdemir F, Cobanoglu U, Kavgaci H, Fidan E, Aydin F: Clear cell hidradenoma of the gluteal region: a case report. Acta Dermatovenerol Croat; 2009;17(2):144-6
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  • Clear cell hidradenoma is a rare skin appendage tumor.
  • Under the epidermis, an eosinophilic-cytoplasm, uniform-appearance, oval-round-nucleus, benign tumor with cystic and solid components was detected.
  • [MeSH-major] Adenoma, Sweat Gland / pathology. Buttocks / pathology. Sweat Gland Neoplasms / pathology

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  • (PMID = 19595274.001).
  • [ISSN] 1330-027X
  • [Journal-full-title] Acta dermatovenerologica Croatica : ADC
  • [ISO-abbreviation] Acta Dermatovenerol Croat
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Croatia
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88. Hsu SD, Chou SJ, Hsieh HF, Chen TW, Cheng MF, Yu JC: Giant malignant mammary phyllodes tumor: report of a case and review of the literature. Onkologie; 2007 Feb;30(1-2):45-7
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  • [Title] Giant malignant mammary phyllodes tumor: report of a case and review of the literature.
  • BACKGROUND: To distinguish between a benign and malignant phyllodes tumor before surgery is difficult.
  • Wide excision or mastectomy with adequate free margins is necessary in the case of a malignant phyllodes tumor.
  • However, repairing the skin defect after removal of a giant malignant phyllodes tumor is a great challenge for the breast surgeon.
  • CASE REPORT: We report the case of a 45-year-old Taiwanese woman with a giant malignant phyllodes tumor measuring 30 x 25 x 22 cm.
  • Prior to surgery, we carefully designed a flap to cover the skin defect, following standard mastectomy with at least 2 cm free margins.
  • CONCLUSION: Giant malignant phyllodes tumors can be treated by total mastectomy with adequate free margins, using a flap technique to cover the skin defect.
  • [MeSH-major] Breast Neoplasms / diagnosis. Breast Neoplasms / surgery. Mastectomy, Simple / methods. Phyllodes Tumor / diagnosis. Phyllodes Tumor / surgery. Surgical Flaps
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Treatment Outcome

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  • (PMID = 17264525.001).
  • [ISSN] 0378-584X
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 7
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89. Golpour M: Evaluation of characteristics of patients with pilomatricoma in Mazandaran Province, 1996-2006. Pak J Biol Sci; 2009 Mar 15;12(6):548-50
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  • Mean age of the patients was 20.1 years .The most frequent sites of the tumor were the forearm (41.30%).
  • It can be concluded, because the pilomatricoma is a benign cutaneous neoplasm with differentiation toward hair matrix, so that it is not seen in palm or plantar surface, but could present in any other area.
  • [MeSH-major] Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 19580010.001).
  • [ISSN] 1028-8880
  • [Journal-full-title] Pakistan journal of biological sciences : PJBS
  • [ISO-abbreviation] Pak. J. Biol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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90. Abraham T, Jackson B, Davis L, Yu J, Peterson C: Mohs surgical treatment of a granular cell tumor on the toe of a child. Pediatr Dermatol; 2007 May-Jun;24(3):235-7
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  • [Title] Mohs surgical treatment of a granular cell tumor on the toe of a child.
  • Granular cell tumors are uncommon, usually benign tumors of neural origin.
  • We report a granular cell tumor on the distal toe of a 5-year-old child, removed with Mohs surgery.
  • Review of the English language literature revealed four previously reported granular cell tumors treated with Mohs micrographic surgery, none of which was in a child.
  • [MeSH-major] Granular Cell Tumor / surgery. Mohs Surgery. Skin Neoplasms / surgery. Toes / surgery

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  • (PMID = 17542870.001).
  • [ISSN] 0736-8046
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Murali R, Palfreeman S: Clear cell atypical fibroxanthoma - report of a case with review of the literature. J Cutan Pathol; 2006 May;33(5):343-8
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  • Clear cell atypical fibroxanthoma (CCAFX) is a rare variant of atypical fibroxanthoma (AFX), a pleomorphic dermal tumour associated with a good prognosis.
  • The tumour cells stained with vimentin, CD68 and CD99 and were cytokeratin-negative.
  • The immunohistochemical and ultrastructural features supported a diagnosis of CCAFX.
  • The diagnosis of CCAFX requires the exclusion of other pleomorphic clear cell tumours that can occur in the skin by using a combination of morphology, immunohistochemistry and electronmicroscopy.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / analysis. Ear / pathology. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission

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  • (PMID = 16640540.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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92. Filler RB, Roberts SJ, Girardi M: Cutaneous two-stage chemical carcinogenesis. CSH Protoc; 2007;2007:pdb.prot4837
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  • [Title] Cutaneous two-stage chemical carcinogenesis.
  • INTRODUCTIONThe induction of cutaneous carcinogenesis in mice by topical administration of chemicals enables the local, systemic, and environmental factors that influence tumor susceptibility, growth, and progression to be studied in the laboratory.
  • Chemical carcinogenesis in mouse skin has been used for several decades, and continues to help in the identification of important molecular and immunological pathways involved in cutaneous malignancy.
  • This protocol describes the two-stage application of chemicals to the skin for the initiation and promotion of cutaneous tumors.
  • Resulting tumors may develop in the form of benign papillomas that regress or progress to SCC, or SCC may arise without an apparent precursor lesion.

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  • (PMID = 21357170.001).
  • [Journal-full-title] CSH protocols
  • [ISO-abbreviation] CSH Protoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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93. Cho MY, Kim HS, Eng C, Kim DS, Kang SJ, Eom M, Yi SY, Bronner MP: First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity. Am J Surg Pathol; 2008 Aug;32(8):1258-64
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  • [Title] First report of ovarian dysgerminoma in Cowden syndrome with germline PTEN mutation and PTEN-related 10q loss of tumor heterozygosity.
  • In her second decade, a hamartomatous soft tissue extremity mass and diffuse gastrointestinal hamartomatous polyposis with pathologic features suggestive of either juvenile, Peutz-Jeghers, or Cowden polyps were identified, along with diffuse esophageal glycogenic acanthosis and skin manifestations.
  • During regular thyroid cancer surveillance under the provisional diagnosis of Cowden syndrome, papillary thyroid carcinoma and benign follicular nodules were diagnosed at age 23.
  • [MeSH-major] Chromosomes, Human, Pair 10. Dysgerminoma / genetics. Germ-Line Mutation. Hamartoma Syndrome, Multiple / diagnosis. Loss of Heterozygosity. Ovarian Neoplasms / genetics. PTEN Phosphohydrolase / genetics

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  • (PMID = 18594467.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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94. González-Vela MC, Val-Bernal JF, González-López MA, Drake M, Fernández-Llaca JH: Pure sclerotic neurofibroma: a neurofibroma mimicking sclerotic fibroma. J Cutan Pathol; 2006 Jan;33(1):47-50
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  • BACKGROUND: Neurofibroma (NF) is a benign tumor of the nerve sheath.
  • METHODS AND RESULTS: The patient was a 61-year-old man who had an asymptomatic cutaneous lesion on the right scapular region.
  • Microscopically, the nodule showed a well-circumscribed, nonencapsulated dermal tumor composed of scant cells and thick collagen bundles with prominent clefts.
  • The tumor cells were immunoreactive for vimentin and S100 protein.
  • CONCLUSION: It is important to recognize this exceptional type of NF because it may be easily confused with SF, as well as with a wide variety of neoplasms or hamartomatous conditions containing similar sclerotic pattern.
  • [MeSH-major] Fibroma / diagnosis. Neurofibroma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Middle Aged. S100 Proteins / analysis. Sclerosis. Vimentin / analysis

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  • (PMID = 16441412.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / Vimentin
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95. Ruddell A, Kelly-Spratt KS, Furuya M, Parghi SS, Kemp CJ: p19/Arf and p53 suppress sentinel lymph node lymphangiogenesis and carcinoma metastasis. Oncogene; 2008 May 15;27(22):3145-55
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  • The ability of tumor cells to metastasize is increasingly viewed as an interaction between the primary tumor and host tissues.
  • Deletion of the p19/Arf or p53 tumor suppressor genes accelerates malignant progression and metastatic spread of 7,12-dimethylbenz(a)anthracene (DMBA)/12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced squamous cell carcinomas, providing a model system to address mechanisms of metastasis.
  • Here, we show that benign pre-metastatic papillomas from wild-type mice trigger lymphangiogenesis within draining lymph nodes, whereas there is no growth of primary tumor lymphatic vessels.
  • Lymph node lymphangiogenesis is greatly accelerated in papilloma-bearing p19/Arf- or p53-deficient mice, which coincides with the greater propensity of these tumors to progress to carcinomas and to metastasize.
  • The extent of accumulation of B cells within the tumor-draining lymph nodes of wild-type mice predicted the level of lymph node lymphangiogenesis and metastatic potential.
  • This immune cell accumulation and lymph node lymphangiogenesis phenotype identifies host anti-tumor responses that could drive metastatic spread of cancers via the lymphatics.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cyclin-Dependent Kinase Inhibitor p16 / physiology. Lymph Nodes / physiology. Lymphangiogenesis / genetics. Lymphatic Metastasis. Skin Neoplasms / pathology. Tumor Suppressor Protein p53 / physiology

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  • (PMID = 18059331.001).
  • [ISSN] 1476-5594
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01-CA68328; United States / NCI NIH HHS / CA / R01-CA99517
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cdkn2a protein, mouse; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Tumor Suppressor Protein p53; 0 / Vascular Endothelial Growth Factor A; 0 / vascular endothelial growth factor A, mouse; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; NI40JAQ945 / Tetradecanoylphorbol Acetate
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96. Senchak AJ, Dann M, Cable B, Bessinger G: Successful treatment of cutaneous hemangioma of infancy with topical imiquimod 5%: a report of 3 cases. Ear Nose Throat J; 2010 Mar;89(3):E21-5
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  • [Title] Successful treatment of cutaneous hemangioma of infancy with topical imiquimod 5%: a report of 3 cases.
  • Hemangioma of infancy is the most common benign tumor of childhood.
  • Most of these tumors spontaneously regress over several years.
  • However, many parents seek treatment for children with cutaneous hemangiomas because of the potential for disfigurement and the attendant psychosocial effects.
  • Based on our experience, we believe that topical imiquimod may be an important tool for the otolaryngologist who treats cutaneous hemangiomas.
  • [MeSH-major] Aminoquinolines / therapeutic use. Antineoplastic Agents / therapeutic use. Hemangioma / drug therapy. Hemangioma / pathology. Skin Neoplasms / drug therapy. Skin Neoplasms / pathology

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  • (PMID = 20229466.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 99011-02-6 / imiquimod
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97. Udapudi DG, Vasudeva P, Srikantiah R, Virupakshappa E: Massive benign phyllodes tumor. Breast J; 2005 Nov-Dec;11(6):521
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  • [Title] Massive benign phyllodes tumor.
  • [MeSH-major] Breast Neoplasms / pathology. Breast Neoplasms / surgery. Phyllodes Tumor / pathology. Phyllodes Tumor / surgery
  • [MeSH-minor] Adult. Biopsy, Needle. Female. Humans. Skin Ulcer / etiology

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  • (PMID = 16297126.001).
  • [ISSN] 1075-122X
  • [Journal-full-title] The breast journal
  • [ISO-abbreviation] Breast J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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98. Lo RS, Witte ON: Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytes. Cancer Res; 2008 Jun 1;68(11):4248-57
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  • Accumulation of distinct sets of genetic/epigenetic alterations is thought to contribute to stepwise progression of human cutaneous melanomas.
  • We found evidence of frequent tumor cell autonomous transforming growth factor-beta (TGF-beta) signal activation in both premalignant and malignant stages of human cutaneous melanoma histogenesis and investigated its potential causative roles using human organotypic skin cultures.
  • PTEN deficiency and Braf activation, two common coincident genetic alterations found in primary cutaneous melanomas, were first introduced into human melanocytes previously immortalized by the SV40 large T antigen and telomerase.
  • These changes individually supported anchorage-independent growth and conferred benign, hyperplastic growth in a skin-like environment.
  • Further addition of cell autonomous TGF-beta activation in the context of PTEN deficiency and Braf activation promoted dermal invasion in skin cultures without significantly promoting proliferation in vitro and in vivo.
  • [MeSH-major] Melanocytes / pathology. Melanoma / pathology. Neoplasm Invasiveness. Transforming Growth Factor beta / physiology

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  • (PMID = 18519684.001).
  • [ISSN] 1538-7445
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / Howard Hughes Medical Institute / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transforming Growth Factor beta; EC 3.1.3.48 / PTEN protein, human; EC 3.1.3.67 / PTEN Phosphohydrolase
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99. Ortonne N, Le Gouvello S, Mansour H, Poillet C, Martin N, Delfau-Larue MH, Leroy K, Farcet JP, Bagot M, Bensussan A: CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome. J Invest Dermatol; 2008 Feb;128(2):465-72
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  • [Title] CD158K/KIR3DL2 transcript detection in lesional skin of patients with erythroderma is a tool for the diagnosis of Sézary syndrome.
  • The distinction between Sézary syndrome (SS) and benign erythrodermic inflammatory diseases (EID) is difficult to make both clinically and on skin biopsies, since histomorphology can provide nonspecific results.
  • New markers of circulating malignant Sézary cells have been recently described, especially CD158k/KIR3DL2 and T-plastin, but it has not been yet determined whether they could help in the diagnosis of erythroderma in skin samples.
  • In this study, 13 frozen skin specimens from 10 SS patients and 26 from EID were analyzed for CD158k/KIR3DL2 expression using immunohistochemistry with AZ158 mAb, which also recognizes the monomeric CD158e/KIR3DL1 receptor.
  • Therefore in all samples disclosing a significant staining with AZ158 mAb, CD158k/KIR3DL2, CD158e/KIR3DL1 and T-plastin mRNA expression were analyzed on the same skin specimen using conventional and/or quantitative real-time reverse transcription (RT)-PCR.
  • Interestingly, only CD158k/KIR3DL2 transcripts were found to be significantly overexpressed in skin biopsies from patients with SS (P<0.0001), including when normalization to CD3 expression was achieved (P=0.0003).
  • In light of these findings, CD158k/KIR3DL2 transcripts appear to be a unique molecular marker of SS in skin samples, allowing differential diagnosis with benign EID in routine practice.
  • [MeSH-major] Biomarkers, Tumor / genetics. Dermatitis, Exfoliative / diagnosis. Receptors, KIR2DL2 / genetics. Sezary Syndrome / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Alternative Splicing. Antibodies, Monoclonal. Biopsy. Cryopreservation. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Membrane Glycoproteins. Microfilament Proteins. Middle Aged. Phosphoproteins / genetics. RNA, Messenger / metabolism. Skin / pathology


100. Burns FJ, Tang MS, Frenkel K, Nádas A, Wu F, Uddin A, Zhang R: Induction and prevention of carcinogenesis in rat skin exposed to space radiation. Radiat Environ Biophys; 2007 Jun;46(2):195-9
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  • [Title] Induction and prevention of carcinogenesis in rat skin exposed to space radiation.
  • A dual-lesion, radiation-track model in rat skin has proven to be consistent with tumor induction data with respect to acute radiation doses ranging from 0.5 up to 10 Gy and higher, and average LETs ranging from 0.34 to 150 keV microm(-1) according to the form neoplastic risk (D,L) = CLD + BD2.
  • A recent result with the 56Fe ion beam showed dose-response consistency for malignant (carcinomas) and benign (fibromas) tumor induction with earlier results utilizing argon and neon ion beams.
  • A discrepancy between the model and experiment was found indicating that proportionality of cancer yield with LET did not occur at 150 versus 125 keV microm(-1), i.e. tumor yield did not increase in spite of a 20% increase of LET, which suggests that a LET response maximum exists at or within this dose range.
  • Concordance between the model and tumor induction data in rat skin implies that potential intervening complexities of carcinogenic progression fail to obscure the basic radiobiological assumptions underpinning the model.
  • Gene expression microarray analysis shows that vitamin A inhibits the expression of about 80% of the inflammation-related genes induced by the radiation and prevents about 46% of the neoplasms associated with 56Fe ion radiation without appearing to interfere with the underlying dose and LET response patterns.
  • [MeSH-major] Cosmic Radiation. Neoplasm Proteins / metabolism. Neoplasms, Radiation-Induced / physiopathology. Neoplasms, Radiation-Induced / prevention & control. Skin Neoplasms / etiology. Skin Neoplasms / physiopathology. Vitamin A / therapeutic use

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  • [Cites] Carcinogenesis. 1995 Dec;16(12):3009-13 [8603477.001]
  • [Cites] Int J Radiat Biol Relat Stud Phys Chem Med. 1977 Aug;32(2):135-44 [302246.001]
  • [Cites] Curr Med Chem. 2005;12(10):1161-208 [15892631.001]
  • [Cites] Cancer Res. 2002 Mar 15;62(6):1641-7 [11912134.001]
  • [Cites] Cancer Lett. 2000 Apr 28;152(1):53-61 [10754206.001]
  • [Cites] Nature. 2002 Dec 19-26;420(6917):860-7 [12490959.001]
  • [Cites] Free Radic Biol Med. 2003 Jul 1;35(1):68-77 [12826257.001]
  • [Cites] Environ Health Perspect. 1989 May;81:67-72 [2667987.001]
  • [Cites] J Radiat Res. 2002 Dec;43 Suppl:S229-32 [12793764.001]
  • [Cites] Neoplasia. 2003 Jul-Aug;5(4):339-46 [14511405.001]
  • [Cites] J Radiat Res. 1991 Dec;32 Suppl 2:202-16 [1823357.001]
  • [Cites] Cancer Lett. 2003 Apr 10;193(1):1-9 [12691817.001]
  • [Cites] Int J Cancer. 1987 Jun 15;39(6):778-84 [3294611.001]
  • [Cites] Adv Space Res. 1994 Oct;14(10):507-19 [11539987.001]
  • [Cites] Cytogenet Genome Res. 2004;104(1-4):14-20 [15162010.001]
  • [Cites] Phys Med. 2001;17 Suppl 1:194-5 [11776259.001]
  • [Cites] Mutat Res. 1995 Jul;337(1):1-7 [7596354.001]
  • [Cites] Mutat Res. 2000 Apr;462(2-3):101-5 [10767621.001]
  • (PMID = 17387500.001).
  • [ISSN] 0301-634X
  • [Journal-full-title] Radiation and environmental biophysics
  • [ISO-abbreviation] Radiat Environ Biophys
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA16087; United States / NIEHS NIH HHS / ES / ES00260
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Radiation-Protective Agents; 11103-57-4 / Vitamin A
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