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1. Koplay M, Toker S, Sahin L, Kilincoglu V: A calcaneal osteochondroma with recurrence in a skeletally mature patient: a case report. Cases J; 2009;2:7013
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  • INTRODUCTION: Osteochondroma is the most common benign tumor of the skeleton.
  • In an adult, growth of an osteochondroma suggests the diagnosis of malignant transformation to a chondrosarcoma.
  • However, enlargement of an osteochondroma reported as benign after skeletal maturity is present in literature.
  • CONCLUSION: It should kept in mind that benign osteochondromas can show symptomatic growth in skeletally mature patients without malignant transformation.

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  • (PMID = 19829896.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2740046
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2. Kosty JW, Moore JG: Juxta-articular myxoma within the suprapatellar pouch masquerading as a ganglion cyst. Orthopedics; 2009 Jul;32(7):527
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  • Following resection of the 6 x 5 x 1.8-cm lesion, histology confirmed a lobular benign tumor with cystic elements recognized in the pathology and radiology literature as juxta-articular myxoma.
  • [MeSH-major] Knee Joint / surgery. Myxoma / diagnosis. Myxoma / surgery. Patella / pathology. Patella / surgery. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Diagnosis, Differential. Ganglion Cysts / diagnosis. Humans. Male. Middle Aged. Treatment Outcome

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  • (PMID = 19634839.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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3. Kim J, Kumar R, Raymond AK, Ayala AG: Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature. Skeletal Radiol; 2010 Jun;39(6):583-7
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  • Chondroblastoma is a benign bone tumor that typically arises in the epiphysis of a long bone.
  • An en bloc surgical resection of the tumor was performed.

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  • (PMID = 19936740.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 12
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4. Kyriakos M, El-Khoury GY, McDonald DJ, Buckwalter JA, Sundaram M, DeYoung B, O'Brien MP: Osteoblastomatosis of bone. A benign, multifocal osteoblastic lesion, distinct from osteoid osteoma and osteoblastoma, radiologically simulating a vascular tumor. Skeletal Radiol; 2007 Mar;36(3):237-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Osteoblastomatosis of bone. A benign, multifocal osteoblastic lesion, distinct from osteoid osteoma and osteoblastoma, radiologically simulating a vascular tumor.
  • Two adult patients are described with multifocal osteolytic lesions radiologically simulating a vascular tumor.
  • The cases are distinguished from multifocal/multicentric osteoid osteoma and osteoblastoma, and from benign and malignant vascular tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Leg Bones / pathology. Osteoblastoma / diagnosis
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Osteoma, Osteoid / diagnosis. Vascular Neoplasms / diagnosis

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  • (PMID = 16639626.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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5. Znati K, Ahaouch M, Fatemi H, Chbani L, Affifi A, Kamaoui I, Bennis S, Amarti A: [Femoral metaphyso-diaphyseal chondroblastoma: a case report]. Rev Chir Orthop Reparatrice Appar Mot; 2007 May;93(3):283-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondroblastoma is a rare benign tumor of cartilage tissue accounting for less than 1% of all bone tumors.
  • The inaugural signs were pain and limited joint motion.
  • We discuss the anatomic aspects and the clinical course of this rare tumor and present current knowledge of the histogenesis.
  • [MeSH-major] Chondroblastoma / diagnosis. Femoral Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Biopsy. Diagnosis, Differential. Diaphyses / pathology. Female. Humans. Immunohistochemistry. Phosphopyruvate Hydratase / analysis. S100 Proteins / analysis. Vimentin / analysis

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  • (PMID = 17534212.001).
  • [ISSN] 0035-1040
  • [Journal-full-title] Revue de chirurgie orthopédique et réparatrice de l'appareil moteur
  • [ISO-abbreviation] Rev Chir Orthop Reparatrice Appar Mot
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / S100 Proteins; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
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6. Sajid MS, Hamilton G, Baker DM, Joint Vascular Research Group: A multicenter review of carotid body tumour management. Eur J Vasc Endovasc Surg; 2007 Aug;34(2):127-30
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  • METHOD: A detailed proforma was designed and sent to all members of Joint Vascular Research Group (JVRG).
  • Duplex scan is the best investigation for diagnosis, though MRI, DSA and CT scan are important for preoperative assessment.
  • Mostly CBT is benign but malignant forms are not uncommon.
  • [MeSH-major] Carotid Body Tumor / surgery. Head and Neck Neoplasms / surgery. Vascular Surgical Procedures

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  • (PMID = 17400487.001).
  • [ISSN] 1078-5884
  • [Journal-full-title] European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery
  • [ISO-abbreviation] Eur J Vasc Endovasc Surg
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
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7. Nissim L, Mackstaller L, Hooten J, Motamedi K, Graham A, Taljanovic M: Spindle-cell sarcoma of the popliteal fossa mimicking a benign vascular lesion. Radiol Case Rep; 2010;5(1):340
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  • [Title] Spindle-cell sarcoma of the popliteal fossa mimicking a benign vascular lesion.
  • While some of these tumors may represent de novo malignant transformation of benign entities, others may present with a long indolent course before their invasive nature is apparent.
  • Magnetic resonance imaging (MRI) suggested a benign vascular lesion/venous angioma, but after the patient's clinical course changed, repeat MRI 18 months later was consistent with an infiltrative soft-tissue malignancy/sarcoma.
  • Three years following the amputation, the patient is free of local tumor recurrence or metastatic disease.

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  • (PMID = 27307844.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4898174
  • [Keywords] NOTNLM ; CT, computed tomography / MRI, magnetic resonance imaging
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8. Miller IJ, Blank A, Yin SM, McNickle A, Gray R, Gitelis S: A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases. Diagn Pathol; 2010;5:62
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  • [Title] A case of recurrent giant cell tumor of bone with malignant transformation and benign pulmonary metastases.
  • Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis.
  • Vascular invasion outside the boundary of the tumor can be seen.
  • Metastasis, with identical morphology to the primary tumor, occurs in a few percent of cases, usually to the lung.
  • [MeSH-major] Bone Neoplasms / pathology. Cell Transformation, Neoplastic / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local. Tibia / pathology

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  • (PMID = 20860830.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bone Cements
  • [Other-IDs] NLM/ PMC2954972
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9. Lee MH, Kim NR, Ryu JA: Cyst-like solid tumors of the musculoskeletal system: an analysis of ultrasound findings. Skeletal Radiol; 2010 Oct;39(10):981-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Twenty-three masses were identified, of which initial interpretation on gray scale included cystic tumor which pathology revealed to be solid tumors.
  • RESULTS: Of 23 masses, there were 5 giant cell tumors of the tendon sheath, 4 schwannomas, 3 vascular leiomyomas, 2 benign fibrous histiocytomas, 2 dermatofibrosarcoma protuberans, 2 granular cell tumors, 1 dermatofibroma, 1 fibroma of the tendon sheath, 1 fibromatosis, 1 eccrine spiradenoma, and 1 granulation tissue.
  • Care should be given to these solid tumors that have a cystic appearance and even lack internal vascularity on color Doppler imaging to enhance diagnosis of cystic and solid masses.

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  • (PMID = 20186412.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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10. Fukunaga S, Futani H, Yoshiya S: Endoscopically assisted resection of a scapular osteochondroma causing snapping scapula syndrome. World J Surg Oncol; 2007;5:37
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  • BACKGROUND: Osteochondroma is the most common benign bone tumor in the scapula.
  • Removal of the tumor was performed by the use of endoscopically assisted resection.
  • The tumor was resected in a piece-by-piece manner by the use of graspers through the same portal.
  • CT images showed complete tumor resection.

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  • (PMID = 17378939.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1839090
  • [General-notes] NLM/ Original DateCompleted: 20070726
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11. Donthineni R, Boriani L, Ofluoglu O, Bandiera S: Metastatic behaviour of giant cell tumour of the spine. Int Orthop; 2009 Apr;33(2):497-501
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  • When there is a recurrence of GCT, with or without metastases, the local and possibly the metastases should be biopsied to confirm the original diagnosis.
  • Progression of benign GCT into an aggressive sarcoma has been documented, and the method of management should be altered.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology
  • [MeSH-minor] Adolescent. Adult. Biopsy, Needle. Combined Modality Therapy. Disease-Free Survival. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Staging. Prognosis. Retrospective Studies. Risk Assessment. Survival Rate. Tomography, X-Ray Computed. Treatment Outcome. Young Adult

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  • [Cites] Clin Orthop Relat Res. 2002 Aug;(401):202-8 [12151897.001]
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  • (PMID = 18461324.001).
  • [ISSN] 1432-5195
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2899057
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12. Chen Q, Jin D, Shi Z, Jing Z: [Resection and reconstruction for tumor of pelvic ring]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi; 2008 Jan;22(1):63-5
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  • [Title] [Resection and reconstruction for tumor of pelvic ring].
  • There were 32 males and 16 females, aged 14-72 years (mean 45.1 years), including 12 cases of benign tumor and 36 cases of malignant tumor.
  • The selection of surgical method: benign tumor in wing of ilium or in sacro-iliac articulation was curettaged, malignant tumors were resected radically or boardly.
  • Benign or malignant tumor in pubis, ischium or pubic symphysis was resected radically, defects were reconstructed with plastic plate or not.
  • For tumor affecting aceta bulum resection of tumor and replacement of the peri-pelvic prothetic or artificial hip joint replacement were performed to reconstruct the function of hip joint.
  • RESULTS: Twelve patients with benign tumors were followed up 12-72 months and could walk well, only 1 case relapsed locally.
  • Thirty-six patients with malignant tumor were followed up 6-72 months, the survival time was 6-12 months in 2 cases (5.6%), 12-24 months in 2 cases (5.6%), 24-36 mongths in 6 cases (16.7%), 36-72 months in 14 cases (38.8%), and more than 72 months in 12 cases (33.3%); 28 patients (77.8%) could walk normally, 6 (16.7%) could walk with the help of walking stick, 2 (5.5%) needed wheel chair to move.
  • Complications occurred in 6 cases (including 2 venous thrombus, 1 anoxic encephalopathy, 2 wound delayed healing, and 1 dislocation after total hip joint replacement); the patients' condition took a turn for the better.
  • CONCLUSION: Operation is a favorable way for the treatment of pelvic tumor.
  • Selecting convenient operation methods to resect tumors or reconstruction defects according the position of the tumor will do good favor to good results, increase the survival time and improve quality of life.
  • [MeSH-major] Bone Neoplasms / surgery. Hip Joint / surgery. Pelvic Bones / surgery. Pelvic Neoplasms / surgery

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  • (PMID = 18361241.001).
  • [ISSN] 1002-1892
  • [Journal-full-title] Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery
  • [ISO-abbreviation] Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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13. Kitsoulis P, Galani V, Stefanaki K, Paraskevas G, Karatzias G, Agnantis NJ, Bai M: Osteochondromas: review of the clinical, radiological and pathological features. In Vivo; 2008 Sep-Oct;22(5):633-46
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  • Osteochondroma is the most common benign bone tumor and usually occurs in the metaphyseal region of the long bones.
  • This tumor takes the form of a cartilage-capped bony outgrowth on the surface of the bone.
  • However, depending on the location of the osteochondroma, significant symptoms may occur as a result of complications such as fracture, bony deformity, mechanical joint problems and vascular or neurologic compromise.

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  • (PMID = 18853760.001).
  • [ISSN] 0258-851X
  • [Journal-full-title] In vivo (Athens, Greece)
  • [ISO-abbreviation] In Vivo
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Chemical-registry-number] EC 2.4.1.- / N-Acetylglucosaminyltransferases; EC 2.4.1.224 / exostosin-1; EC 2.4.1.224 / exostosin-2
  • [Number-of-references] 125
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14. Katthagen BD, Prub A: [Bone allografting]. Orthopade; 2008 Aug;37(8):764-71
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  • Bone allografts are most often used in revision total joint arthroplasty.
  • In cases of reconstruction of defects in benign bone tumors and tumor-like lesions, bone allografts are often suitable.

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  • (PMID = 18584151.001).
  • [ISSN] 0085-4530
  • [Journal-full-title] Der Orthopade
  • [ISO-abbreviation] Orthopade
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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15. Sanghvi DA, Purandare NC, Jambhekar NA, Agarwal MG, Agarwal A: Diffuse-type giant cell tumor of the subcutaneous thigh. Skeletal Radiol; 2007 Apr;36(4):327-30
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  • [Title] Diffuse-type giant cell tumor of the subcutaneous thigh.
  • Diffuse-type giant cell tumor is an extra-articular form of pigmented villonodular synovitis.
  • The localized form of this lesion (tenosynovial giant cell tumor) is frequent, representing the most common subset arising from the synovium of a joint, bursa or tendon sheath, with 85% of cases occurring in the fingers.
  • The less frequent diffuse-type giant cell tumors are commonly located in the periarticular soft tissues, but on rare occasions these lesions can be purely intramuscular or subcutaneous We report the case of a 26-year-old female with diffuse-type giant cell tumor of the subcutaneous thigh, remote from a joint, bursa or tendon sheath.
  • A review of the literature did not reveal any similar description of a diffuse-type giant cell tumor completely within the subcutaneous thigh, remote from a joint, bursa or tendon sheath.
  • These lesions were initially regarded as inflammatory or reactive processes, but since the identification of clonal abnormalities in these patients, and in view of their capacity for autonomous growth, they are now widely considered to represent benign neoplasms.
  • [MeSH-major] Giant Cell Tumors / diagnosis. Soft Tissue Neoplasms / diagnosis. Subcutaneous Tissue / pathology. Thigh / pathology

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  • (PMID = 16565836.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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16. Cosso R, Nuzzo V, Zuccoli A, Brandi ML, Falchetti A: Giant cell tumor in a case of Paget's disease of bone: an aggressive benign tumor exhibiting a quick response to an innovative therapeutic agent. Clin Cases Miner Bone Metab; 2010 May;7(2):145-52
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  • [Title] Giant cell tumor in a case of Paget's disease of bone: an aggressive benign tumor exhibiting a quick response to an innovative therapeutic agent.
  • Giant cell tumor of bone, also called osteoclastoma, is a rare skeletal complication of Paget's disease of bone.
  • We will focus on either a review on this rare bone tumor, including some genetic aspects, or the current established therapies.

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  • (PMID = 22460021.001).
  • [ISSN] 1971-3266
  • [Journal-full-title] Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases
  • [ISO-abbreviation] Clin Cases Miner Bone Metab
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC3004463
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17. Pennekamp W, Peters S, Schinkel C, Kuhnen C, Nicolas V, Muhr G, Frangen TM: Aneurysmal bone cyst of the cervical spine (2008:7b). Eur Radiol; 2008 Oct;18(10):2356-60
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  • Aneurysmal bone cysts (ABC) are rare, benign, but locally destructive bone tumors.
  • In CT and MRI, there was a soft-tissue tumor mass with multiple cysts and fluid-fluid levels within these cysts, as well as contrast enhancement of the cyst wall and the tissue among the cysts.
  • The tumor was resected en bloc, after which the patient underwent adjuvant radiation therapy.
  • [MeSH-major] Bone Cysts, Aneurysmal / diagnosis. Cervical Vertebrae / diagnostic imaging. Cervical Vertebrae / pathology. Magnetic Resonance Imaging. Spinal Diseases / diagnosis. Tomography, X-Ray Computed


18. Fnini S, Labsaili N, Messoudi A, Largab A: [Giant cell tumor of the thumb proximal phalanx: resection-iliac graft and double arthrodesis]. Chir Main; 2008 Feb;27(1):54-7
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  • [Title] [Giant cell tumor of the thumb proximal phalanx: resection-iliac graft and double arthrodesis].
  • Giant cell tumours (GCT) of bone are frequent, with variable behaviour, high risk of recurrence and an often benign histological appearance.
  • After a surgical biopsy, we performed an "en bloc" resection of the first phalanx, with an iliac crest graft reconstruction and a double arthrodesis of the metacarpophalangeal and interphalangeal joint.
  • [MeSH-major] Bone Neoplasms. Giant Cell Tumor of Bone. Thumb
  • [MeSH-minor] Arthrodesis. Biopsy. Bone Nails. Bone Transplantation. Finger Joint. Follow-Up Studies. Fracture Fixation, Internal / instrumentation. Fractures, Spontaneous / etiology. Fractures, Spontaneous / surgery. Humans. Male. Metacarpophalangeal Joint. Middle Aged. Neoplasm Staging. Patient Satisfaction. Time Factors. Treatment Outcome

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  • (PMID = 18248835.001).
  • [ISSN] 1297-3203
  • [Journal-full-title] Chirurgie de la main
  • [ISO-abbreviation] Chir Main
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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19. Ozalay M, Tandoğan RN, Akpinar S, Cesur N, Hersekli MA, Ozkoç G, Uysal M: Arthroscopic treatment of solitary benign intra-articular lesions of the knee that cause mechanical symptoms. Arthroscopy; 2005 Jan;21(1):12-8
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  • [Title] Arthroscopic treatment of solitary benign intra-articular lesions of the knee that cause mechanical symptoms.
  • Intra-articular benign tumors or tumor-like lesions can present with symptoms that resemble acute mechanical derangement.
  • METHODS: Our review revealed 33 patients with benign intra-articular masses in the knee joint.
  • Preoperative magnetic resonance imaging confirmed the diagnosis in 7 cases and 12 cases were diagnosed during knee arthroscopy.
  • CONCLUSIONS: Solitary benign intra-articular lesions should be considered a rare cause of mechanical knee symptoms.
  • [MeSH-major] Arthroscopy. Knee Joint / surgery
  • [MeSH-minor] Adolescent. Adult. Biomechanical Phenomena. Female. Humans. Joint Diseases / pathology. Joint Diseases / physiopathology. Joint Diseases / surgery. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies

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  • (PMID = 15650661.001).
  • [ISSN] 1526-3231
  • [Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • [ISO-abbreviation] Arthroscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Kuhne M, Boniquit N, Ghodadra N, Romeo AA, Provencher MT: The snapping scapula: diagnosis and treatment. Arthroscopy; 2009 Nov;25(11):1298-311
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  • [Title] The snapping scapula: diagnosis and treatment.
  • Understanding the anatomy of the scapula and surrounding neurovascular structures is crucial in making a differential diagnosis and providing both nonoperative and surgical treatments.
  • Benign tumor conditions of the scapula can also predispose one to snapping scapula syndrome and should be thoroughly investigated during the course of treatment.
  • [MeSH-major] Musculoskeletal Diseases / diagnosis. Scapula
  • [MeSH-minor] Acromioclavicular Joint / anatomy & histology. Humans. Thoracic Wall / anatomy & histology

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  • [CommentIn] Arthroscopy. 2010 Mar;26(3):299-300; author reply 301 [20206036.001]
  • (PMID = 19896053.001).
  • [ISSN] 1526-3231
  • [Journal-full-title] Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
  • [ISO-abbreviation] Arthroscopy
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Peng Z, Shan C, Wang H: [Value of promoter methylation of RASSF1A, p16, and DAPK genes in induced sputum in diagnosing lung cancers]. Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2010 Mar;35(3):247-53
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  • METHODS: Methylation-specific PCR (MSP) was used to detect the promoter methylation status of RASSF1A, p16, and DAPK genes in induced sputum and pathological tissues from 82 patients with lung cancers and 25 patients with pulmonary benign lesion.
  • The promoter methylation of RASSF1A,p16, and DAPK genes were not detected in patients with pulmonary benign lesion.
  • There was a significant difference between the lung cancer group and pulmonary benign lesion group (P<0.05).
  • The methylation rate of joint detecting RASSF1A, p16, and DAPK genes was 73.2%.
  • CONCLUSION: Joint detection for promoter hypermethylation of RASSF1A, p16, and DAPK genes in induced sputum may be used as a simple and effective index of the diagnosis and prognose of lung cancers, and can improve the positive rate.
  • [MeSH-major] Apoptosis Regulatory Proteins / genetics. Calcium-Calmodulin-Dependent Protein Kinases / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. Lung Neoplasms / diagnosis. Sputum / metabolism. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / genetics. Aged. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / genetics. DNA Methylation. Death-Associated Protein Kinases. Female. Humans. Male. Middle Aged. Polymerase Chain Reaction / methods. Promoter Regions, Genetic / genetics

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  • (PMID = 20360646.001).
  • [ISSN] 1672-7347
  • [Journal-full-title] Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
  • [ISO-abbreviation] Zhong Nan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / RASSF1 protein, human; 0 / Tumor Suppressor Proteins; EC 2.7.11.1 / Death-Associated Protein Kinases; EC 2.7.11.17 / Calcium-Calmodulin-Dependent Protein Kinases
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22. Cao Y, Paner GP, Perry KT, Flanigan RC, Campbell SC, Picken MM: Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System. Arch Pathol Lab Med; 2005 Apr;129(4):487-91
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  • [Title] Renal neoplasms in younger adults: analysis of 112 tumors from a single institution according to the new 2004 World Health Organization classification and 2002 American Joint Committee on Cancer Staging System.
  • Recent modification of the World Health Organization histologic classification and the American Joint Committee on Cancer staging system of adult renal tumors further highlighted the need for case analysis in this age group.
  • The tumors were reevaluated according to the 2004 World Health Organization classification and the 2002 American Joint Committee on Cancer staging system.
  • Seventeen percent of these tumors had multilocular cystic features involving more than 50% of the tumor volume (55%-85%).
  • The number of oncocytomas was also significantly lower in younger adults than in older adults (2% vs 11%, P < .001), and this presumably age-related benign neoplasm was not identified in patients younger than 40 years in this study.
  • In contrast, the miscellaneous tumor category showed a remarkable increase, from 4% in older adults to 26% in younger adults (P < .001).
  • Younger female adults tended to have more benign miscellaneous neoplasms than did their male counterparts (64% vs 36%, P < .001).
  • Malignant and benign renal neoplasms tend to have a contrasting sex distribution in younger adults.
  • [MeSH-minor] Adult. Age Distribution. Female. Humans. Male. Neoplasm Staging. Sex Distribution

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  • (PMID = 15794671.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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23. Mohler DG, Chiu R, McCall DA, Avedian RS: Curettage and cryosurgery for low-grade cartilage tumors is associated with low recurrence and high function. Clin Orthop Relat Res; 2010 Oct;468(10):2765-73
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  • Grade 1 chondrosarcomas have little or no metastatic potential and are often difficult to distinguish from painful benign enchondromas.
  • Patients were followed a minimum of 18 months (average, 47.2. months; range, 18-134 months) for evidence of recurrence and for assessment of Musculoskeletal Tumor Society (MSTS) functional score.
  • RESULTS: Two of the 46 patients had recurrences in the original tumor site (4.3% recurrence rate), which subsequently were removed by wide excision, and both patients were confirmed to be disease-free 36 and 30 months, respectively, after the second surgery.
  • [MeSH-minor] Adolescent. Adult. Aged. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local. Neoplasm Staging. Recovery of Function. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 20574801.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3049634
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24. Previgliano CH, Sangster GP, Simoncini AA, Carbó AI, González E, Li B, D'Agostino H: Parosteal lipoma of the rib: a benign condition that mimics malignancy. J La State Med Soc; 2010 Jan-Feb;162(1):40-3
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  • [Title] Parosteal lipoma of the rib: a benign condition that mimics malignancy.
  • Albeit a benign condition, PL imaging findings may be misinterpreted as a malignant lesion.
  • Lipomas are benign tumors consisting of mature fat cells.
  • Musculoskeletal lipomatous lesions may be located in bones, soft tissues, and may also affect joint and tendon sheaths.
  • PL is a rare benign deep fatty-tissue tumor that arises contiguous to the periosteum without originating from it.
  • [MeSH-minor] Biopsy. Diagnosis, Differential. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 20336957.001).
  • [ISSN] 0024-6921
  • [Journal-full-title] The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society
  • [ISO-abbreviation] J La State Med Soc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Stanojević G, Jovanović M, Stojanović M, Rancić Z, Dordević-Jovanović L, Miladinovic-Tasić N: [Primary pelvic hydatid cyst--case report]. Med Pregl; 2009 Nov-Dec;62(11-12):587-91
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  • CASE REPORT: The case of a 65-year-old woman is reported, who was admitted for surgical treatment of incidentally detected pelvis tumor of unclear origin.
  • Intraoperatively, it was noted that the tumor in the pelvis was cystic, resembling a hydatid disease, involving left pararectal space and extending to the sacroiliac joint.
  • The principal goal is the compromise between the need to completely remove the cyst and the fact that it is a benign disease so the patient should not be unnecessarily exposed to an increased operative risk.
  • [MeSH-major] Echinococcosis / diagnosis. Pelvic Infection / diagnosis

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  • (PMID = 20491387.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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26. Kim J, Takeuchi H, Lam ST, Turner RR, Wang HJ, Kuo C, Foshag L, Bilchik AJ, Hoon DS: Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival. J Clin Oncol; 2005 Apr 20;23(12):2744-53
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  • METHODS: CRC cell lines (n = 6) and tumor specimens (n = 139) from patients with different American Joint Committee on Cancer (AJCC) stages of CRC were assessed.
  • CXCR4 expression in tumor and benign specimens was assessed by quantitative real-time reverse transcription polymerase chain reaction and correlated with disease recurrence and overall survival.
  • RESULTS: High CXCR4 expression in tumor specimens (n = 57) from AJCC stage I/II patients was associated with increased risk for local recurrence and/or distant metastasis (risk ratio, 1.35; 95% CI, 1.09 to 1.68; P = .0065).
  • High CXCR4 expression in primary tumor specimens (n = 35) from AJCC stage IV patients correlated with worse overall median survival (9 months v 23 months; RR, 2.53; 95% CI, 1.19 to 5.40; P = .016).
  • [MeSH-major] Colorectal Neoplasms / genetics. Colorectal Neoplasms / pathology. Gene Expression Profiling. Liver Neoplasms / genetics. Liver Neoplasms / secondary. Neoplasm Recurrence, Local / genetics. Receptors, CXCR4 / biosynthesis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Metastasis / physiopathology. Prognosis. Risk Factors. Signal Transduction. Survival Analysis. Tumor Cells, Cultured

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  • (PMID = 15837989.001).
  • [ISSN] 0732-183X
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01-CA90848-02
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, CXCR4
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27. Campanacci DA, Scoccianti G, Beltrami G, Mugnaini M, Capanna R: Ankle arthrodesis with bone graft after distal tibia resection for bone tumors. Foot Ankle Int; 2008 Oct;29(10):1031-7
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  • Ankle arthrodesis has proven to be an effective treatment in primary and post-traumatic joint arthritis, but few papers have addressed the feasibility and techniques of ankle arthrodesis in tumor surgery after long bone resections.
  • MATERIALS AND METHODS: Resection of the distal tibia and reconstruction by ankle fusion using non-vascularized structural bone grafts was performed in 8 patients affected by malignant (5 patients) or aggressive benign (3 patients) tumors.
  • CONCLUSION: Resection of the distal tibia and arthrodesis of the ankle with non-vascularized structural bone grafts, combined with autologous bone chips, can be an effective procedure in bone tumor surgery with durable and satisfactory functional results.
  • [MeSH-major] Ankle Joint / surgery. Arthrodesis. Bone Neoplasms / surgery. Tibia / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Bone Nails. Bone Plates. Female. Fibula / transplantation. Follow-Up Studies. Giant Cell Tumor of Bone / surgery. Hemangioendothelioma / surgery. Histiocytoma, Benign Fibrous / surgery. Humans. Ilium / transplantation. Limb Salvage. Male. Middle Aged. Pain Measurement. Postoperative Complications. Retrospective Studies. Sarcoma / surgery. Transplantation, Autologous. Transplantation, Homologous. Treatment Outcome

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  • (PMID = 18851821.001).
  • [ISSN] 1071-1007
  • [Journal-full-title] Foot & ankle international
  • [ISO-abbreviation] Foot Ankle Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Villalobos CE, Rybak LD, Steiner GC, Wittig JC: Osteoblastoma of the sternum--case report and review of the literature. Bull NYU Hosp Jt Dis; 2010;68(1):55-9
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  • Osteoblastoma does not have a classic presentation, but can vary with the location and size of the tumor.
  • The main complaint is often progressive pain localized at the tumor site.
  • Osteoblastoma is a benign tumor with an aggressive behavior.

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  • (PMID = 20345366.001).
  • [ISSN] 1936-9727
  • [Journal-full-title] Bulletin of the NYU hospital for joint diseases
  • [ISO-abbreviation] Bull NYU Hosp Jt Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Polypropylenes; 196OC77688 / Methylmethacrylate
  • [Number-of-references] 22
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29. Balke M, Streitbuerger A, Budny T, Henrichs M, Gosheger G, Hardes J: Treatment and outcome of giant cell tumors of the pelvis. Acta Orthop; 2009 Oct;80(5):590-6
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  • METHODS: 20 patients with histologically benign GCT of the pelvis were included in this study.
  • RESULTS: 1 patient with a pubic tumor developed a local recurrence 1 year after intralesional resection and additional curettage of the margins.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Pelvic Bones
  • [MeSH-minor] Adult. Aged. Bone Cements. Bone Transplantation. Curettage. Embolization, Therapeutic / methods. Female. Follow-Up Studies. Humans. Ilium / pathology. Ilium / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome

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  • (PMID = 19916695.001).
  • [ISSN] 1745-3682
  • [Journal-full-title] Acta orthopaedica
  • [ISO-abbreviation] Acta Orthop
  • [Language] eng
  • [Publication-type] Journal Article
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30. Khashan M, Haim A, Chechick O, Dekel S: Longstanding knee joint preserved functional outcome following medial femoral condyle resection. A case report. Knee; 2010 Aug;17(4):303-5
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  • [Title] Longstanding knee joint preserved functional outcome following medial femoral condyle resection. A case report.
  • Giant cell tumor of the bone (GCT) is a relatively uncommon benign aggressive tumor that occurs near the articular surface of major joints.
  • Unicondylar osteoarticular resection is usually followed by a reconstructive procedure to restore the biomechanical demands of the joint.
  • [MeSH-major] Bone Neoplasms / surgery. Femur / surgery. Giant Cell Tumor of Bone / surgery. Knee Joint / surgery

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  • [Copyright] Copyright 2010 Elsevier B.V. All rights reserved.
  • (PMID = 20303764.001).
  • [ISSN] 1873-5800
  • [Journal-full-title] The Knee
  • [ISO-abbreviation] Knee
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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31. Rimondi E, Bianchi G, Malaguti MC, Ciminari R, Del Baldo A, Mercuri M, Albisinni U: Radiofrequency thermoablation of primary non-spinal osteoid osteoma: optimization of the procedure. Eur Radiol; 2005 Jul;15(7):1393-9
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  • Osteoid osteoma is a small benign tumor that requires treatment due to the intense pain it causes.

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  • (PMID = 15756555.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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32. Bhojraj SY, Nene A, Mohite S, Varma R: Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases. Indian J Orthop; 2007 Apr;41(2):146-50
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  • [Title] Giant cell tumor of the spine: A review of 9 surgical interventions in 6 cases.
  • BACKGROUND: Giant cell tumor (GCT) of the spine is uncommon but most aggressive benign tumor of the spine with unpredictable outcome.
  • Preoperative tissue diagnosis was available only in the five recurrences (tissue from the old resection).
  • Posterior only (n=2), anterior only (n=4) and single-stage back and front (n=3) surgeries were carried out depending on the nature of the tumor.
  • Two out of our four new patients had tumor recurrence and both needed repeat resection.
  • Close follow up is needed for early diagnosis of recurrences.

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  • (PMID = 21139768.001).
  • [ISSN] 0019-5413
  • [Journal-full-title] Indian journal of orthopaedics
  • [ISO-abbreviation] Indian J Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2989139
  • [Keywords] NOTNLM ; GCT / Giant Cell Tumor of the spine / radiotherapy
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33. Conaghan PG, Hensor EM, Keenan AM, Morgan AW, Emery P, YEAR Consortium: Persistently moderate DAS-28 is not benign: loss of function occurs in early RA despite step-up DMARD therapy. Rheumatology (Oxford); 2010 Oct;49(10):1894-9
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  • [Title] Persistently moderate DAS-28 is not benign: loss of function occurs in early RA despite step-up DMARD therapy.
  • OBJECTIVES: Current UK management of RA initially employs conventional DMARDs, with biological therapy reserved for DMARD-resistant RA patients with persistently high 28-joint disease activity score (DAS-28).
  • [MeSH-major] Antirheumatic Agents / therapeutic use. Arthritis, Rheumatoid / physiopathology. Disability Evaluation. Severity of Illness Index. Tumor Necrosis Factor-alpha / antagonists & inhibitors

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  • (PMID = 20542894.001).
  • [ISSN] 1462-0332
  • [Journal-full-title] Rheumatology (Oxford, England)
  • [ISO-abbreviation] Rheumatology (Oxford)
  • [Language] eng
  • [Grant] United Kingdom / Arthritis Research UK / / 18475; United Kingdom / Arthritis Research UK / /
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antirheumatic Agents; 0 / Tumor Necrosis Factor-alpha
  • [Investigator] Emery P; Conaghan P; Ann A; Keenan AM; Hensor E; Quinn M; Gough A; Green M; Reece R; Hordon L; Helliwell P; Melsom R; Doherty S; Adebajo A; Harvey A; Jarrett S; Huson G; Isdale A; Martin M; Karim Z; McGonagle D; Pease C; Cox S; Bejarano V; Nam J; Villeneuve E; Twigg S; Brown C; Thomas C; Pickles D; Hammond A; Neville B; Fairclough A; Nunns C; Gill A; Green J; Rhys-Evans B; Padwell B; Madde J; Taylor L; Smith S; King H; Firth J; Heard J; Sigsworth L; Corscadden D; Henshaw K; Rashid LH; Martin SG; Robinson JI; Kozera L; Fahy S; Paterson A
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34. Holzapfel BM, Geitner U, Diebold J, Glaser C, Jansson V, Dürr HR: Synovial hemangioma of the knee joint with cystic invasion of the femur: a case report and review of the literature. Arch Orthop Trauma Surg; 2009 Feb;129(2):143-8
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  • [Title] Synovial hemangioma of the knee joint with cystic invasion of the femur: a case report and review of the literature.
  • Synovial hemangioma is a rare benign intra-articular tumor.
  • It may be a cause of pain and recurrent joint swelling in children and young adults.
  • This report presents a 29-year-old patient with a synovial hemangioma in the left knee joint.
  • The tumor was locally excised and a partial synovectomy was performed.
  • Histological examination confirmed the diagnosis of a synovial hemangioma.
  • In a review of the recent literature we report the common features of a synovial hemangioma, with emphasis on its diagnosis and therapy.
  • [MeSH-major] Femur / surgery. Hemangioma / diagnosis. Joint Diseases / diagnosis. Knee Joint. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 18758797.001).
  • [ISSN] 1434-3916
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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35. Puri A, Agarwal M: Treatment of giant cell tumor of bone: Current concepts. Indian J Orthop; 2007 Apr;41(2):101-8
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  • [Title] Treatment of giant cell tumor of bone: Current concepts.
  • Giant cell tumor (GCT) of bone though one of the commonest bone tumors encountered by an orthopedic surgeon continues to intrigue treating surgeons.
  • Usually benign, they are locally aggressive and may occasionally undergo malignant transformation.

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  • (PMID = 21139760.001).
  • [ISSN] 0019-5413
  • [Journal-full-title] Indian journal of orthopaedics
  • [ISO-abbreviation] Indian J Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2989131
  • [Keywords] NOTNLM ; Curettage / giant cell tumor / treatment
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36. Rubin G, Wolovelsky A, Rinott M, Rozen N: Osteoid osteoma of the hamate: an unusual cause of ulnar-sided wrist pain. Orthopedics; 2010 Jul;33(7):513
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  • Osteoid osteoma is a benign skeletal neoplasm of unknown etiology that is composed of osteoid and woven bone.
  • Its incidence is 11% of benign tumors and 3% of all primary bone tumors, with 6% to 13% of all cases occurring in the hand.
  • Osteoid osteoma of the hamate can produce ulnar-sided wrist pain in the dorsal or volar aspect of the wrist, depending on the location of the tumor in the bone.
  • A tumor located in the hook will produce volar pain.
  • [MeSH-major] Arthralgia / diagnosis. Bone Neoplasms / pathology. Hamate Bone / pathology. Osteoma, Osteoid / pathology. Ulna / pathology
  • [MeSH-minor] Humans. Male. Treatment Outcome. Wrist Joint / pathology. Wrist Joint / physiopathology. Wrist Joint / surgery. Young Adult

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  • [Copyright] Copyright 2010, SLACK Incorporated.
  • (PMID = 20608627.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Bassiony AA, Abdelrahman M, Abdelhady A, Assal MK: Resection arthrodesis for the management of aggressive giant cell tumor of the distal femur. Indian J Orthop; 2009 Jan;43(1):67-71
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  • [Title] Resection arthrodesis for the management of aggressive giant cell tumor of the distal femur.
  • BACKGROUND: Giant cell tumors (GCTs) of bone are aggressive benign tumors.
  • Wide resection and mobile joint reconstruction are preferable for treating tumors around the knee.
  • The functional evaluation was done using the standard system of musculoskeletal tumor society with its modification developed by Enneking et al.
  • Resection arthrodesis offers a biological reconstruction alternative to amputation in a special group of patients when extensive resection precludes mobile joint reconstruction.

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  • (PMID = 19753183.001).
  • [ISSN] 0019-5413
  • [Journal-full-title] Indian journal of orthopaedics
  • [ISO-abbreviation] Indian J Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2739496
  • [Keywords] NOTNLM ; Giant cell tumor / intra medullary nail / resection arthrodesis
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38. Dominkus M, Ruggieri P, Bertoni F, Briccoli A, Picci P, Rocca M, Mercuri M: Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution. Int Orthop; 2006 Dec;30(6):499-504
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  • [Title] Histologically verified lung metastases in benign giant cell tumours--14 cases from a single institution.
  • From 1975 to 1997, 649 cases of benign giant cell tumours of the bone were treated at the Istituto Rizzoli.
  • The time interval between the diagnosis and the appearance of the lung metastases ranged from 3 months to 11.9 years.
  • In contrast to previous reports, we could not detect a predominance of the distal radius, but all of the patients had a stage III tumour according to the Enneking criteria of benign lesions.
  • We conclude that even metastatic benign giant cell tumours have an excellent prognosis after adequate resection.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumor of Bone / secondary. Lung Neoplasms / secondary. Neoplasm Recurrence, Local / pathology

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  • (PMID = 16909252.001).
  • [ISSN] 0341-2695
  • [Journal-full-title] International orthopaedics
  • [ISO-abbreviation] Int Orthop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC3172731
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39. Koukoutsis I, Pappas A, Karanikas G, Kotzadimitriou K, Chrysikos J, Tzika S, Koronakis N, Karavitis G, Lagoudianakis E, Manouras A: Desmoid tumor of the supraclavicular region: a case report. Cases J; 2009;2:7222
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  • [Title] Desmoid tumor of the supraclavicular region: a case report.
  • Desmoid tumors are rare, benign fibroblastic tumors that are locally infiltrative and can cause extensive morbidity by destruction of adjacent vital structures.
  • We report a case of a patient with a desmoid tumor of the left supraclavicular region that was diagnosed and treated in our department and a review of the current literature.

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  • (PMID = 19829936.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2740207
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40. Keser S, Bayar A, Numanoğlu G: An unusual cause for anterior knee pain: strangulated intra-articular lipoma. Knee Surg Sports Traumatol Arthrosc; 2005 Oct;13(7):585-8
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  • Lipoma is the most frequently encountered benign soft tissue tumor.
  • Magnetic resonance imaging revealed an intra-articular tumor of the knee joint.
  • Arthroscopic intervention and subsequent histological examination resulted in the diagnosis of strangulated lipoma originating from infrapatellar fat pad.
  • [MeSH-major] Knee Joint / pathology. Lipoma / diagnosis
  • [MeSH-minor] Adult. Arthroscopy. Female. Humans. Joint Diseases / diagnosis. Joint Diseases / surgery. Magnetic Resonance Imaging. Pain / etiology. Patella / pathology

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  • (PMID = 16208424.001).
  • [ISSN] 0942-2056
  • [Journal-full-title] Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
  • [ISO-abbreviation] Knee Surg Sports Traumatol Arthrosc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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41. Fraquet N, Faizon G, Rosset P, Phillipeau J-, Waast D, Gouin F: Long bones giant cells tumors: treatment by curretage and cavity filling cementation. Orthop Traumatol Surg Res; 2009 Oct;95(6):402-6
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  • OBJECTIVE: Giant cell tumors (GCT) of bone are benign tumors with local aggressiveness that most of the time occur around the metaphyseal area of long bones, often in contact with the articular cartilage.
  • Preoperative radiological evaluation with standard X-rays showed that the tumor measured a mean 71x45mm, for a mean volume of 78cm(3).
  • Diagnosis of recurrence can be made earlier because of the thin scalable border at the bone-cement interface.
  • [MeSH-major] Bone Cements / therapeutic use. Bone Neoplasms / surgery. Femur / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Tibia / surgery

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  • [Copyright] 2009 Elsevier Masson SAS. All rights reserved.
  • (PMID = 19767256.001).
  • [ISSN] 1877-0568
  • [Journal-full-title] Orthopaedics & traumatology, surgery & research : OTSR
  • [ISO-abbreviation] Orthop Traumatol Surg Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Bone Cements
  • [General-notes] NLM/ Original DateCompleted: 20100201
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42. Bush LA, Gayle RB, Berkey BD: Multicentric Osteoid Osteoma Presenting a Diagnostic Dilemma. Radiol Case Rep; 2008;3(3):217
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  • We present a case of a relatively common benign tumor that was a diagnostic dilemma because of its atypical appearance in multiple imaging modalities.
  • After biopsy achieved a definite diagnosis, this tumor was successfully treated with radiofrequency ablation of all nidi in one session.

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  • (PMID = 27303550.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4897034
  • [Keywords] NOTNLM ; CT, computed tomography / ESR, ertythrocyte sedimentation rate / MRI, magnetic resonance imaging / WBC, white blood cell
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43. Singhal V, Sharma SC, Anil J, Sachan PK, Harsh M, Singhal S, Raghuvanshi S: Giant benign nodular hidradenoma of the shoulder: A rare tumor in orthopedic practice. Int J Shoulder Surg; 2010 Oct;4(4):93-6
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  • [Title] Giant benign nodular hidradenoma of the shoulder: A rare tumor in orthopedic practice.
  • A clear cell hidradenoma is a rare dermal tumor, which is believed to originate from the apical portion of the sweat glands.
  • This lesion has not been reported to be large enough to impinge a joint range of motion.
  • We present a giant benign nodular hidradenoma presenting as painful restriction of the right shoulder joint in a 35-year-old male.

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  • (PMID = 21655004.001).
  • [ISSN] 0973-6042
  • [Journal-full-title] International journal of shoulder surgery
  • [ISO-abbreviation] Int J Shoulder Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] South Africa
  • [Other-IDs] NLM/ PMC3100814
  • [Keywords] NOTNLM ; Axillary mass / nodular hidradenoma
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44. Badar F, Moid I, Waheed F, Zaidi A, Naqvi B, Yunus S: Variables associated with recurrence in breast cancer patients-the Shaukat Khanum Memorial experience. Asian Pac J Cancer Prev; 2005 Jan-Mar;6(1):54-7
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  • Those who presented with benign tumors, carcinoma in situ, or metastases were excluded from the analyses.
  • Age, tumor size, nodal status, menopause, estrogen receptor (ER), and progesterone receptor (PR) status, at the time of presentation, were determined.
  • Tumors were classified according to the TNM classification (American Joint Commission on Cancer (AJCC)-sixth edition), and subsequently, grouped into T1/T2 and T3/T4.
  • [MeSH-major] Breast Neoplasms / pathology. Neoplasm Recurrence, Local
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Chi-Square Distribution. Female. Follow-Up Studies. Humans. Logistic Models. Middle Aged. Neoplasm Metastasis. Neoplasm Staging. Pakistan / epidemiology. Registries. Risk Factors

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  • (PMID = 15780033.001).
  • [ISSN] 1513-7368
  • [Journal-full-title] Asian Pacific journal of cancer prevention : APJCP
  • [ISO-abbreviation] Asian Pac. J. Cancer Prev.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Thailand
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45. Carlson JA, Ross JS, Slominski AJ: New techniques in dermatopathology that help to diagnose and prognosticate melanoma. Clin Dermatol; 2009 Jan-Feb;27(1):75-102
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  • Routine light microscopy supplemented with immunohistochemistry in cases of metastatic or spindle cell melanoma are standards of care for the diagnosis and staging of melanoma.
  • Not all melanocytic tumors can be confidently classified as melanoma or benign nevus by histology, however.
  • In addition, tumor thickness and ulceration, the current American Joint Classification on Cancer prognosticators for primary cutaneous (stages I and II) melanoma used in clinical practice, do not perfectly predict an individual's clinical course.
  • Recent advances in molecular techniques and bioinformatics mandate testing and use of novel methods for the detection, diagnosis, and classification of melanocytic tumors that can accurately predict tumor behavior and help in selecting the most optimal and individualized therapy.
  • [MeSH-minor] Cytogenetic Analysis. Dermatology / methods. Humans. Immunohistochemistry. Molecular Diagnostic Techniques. Neoplasm Staging. Prognosis

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  • (PMID = 19095155.001).
  • [ISSN] 1879-1131
  • [Journal-full-title] Clinics in dermatology
  • [ISO-abbreviation] Clin. Dermatol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 288
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46. Gould CF, Ly JQ, Lattin GE Jr, Beall DP, Sutcliffe JB 3rd: Bone tumor mimics: avoiding misdiagnosis. Curr Probl Diagn Radiol; 2007 May-Jun;36(3):124-41
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  • [Title] Bone tumor mimics: avoiding misdiagnosis.
  • Whether discovered incidentally or as part of a focused diagnostic evaluation, the finding of a benign osseous lesion that has radiologic features resembling a bone tumor is not uncommon.
  • Some of the more common benign and nonneoplastic entities that can sometimes be confused with tumors are the following: cortical desmoid, Brodie abscess, synovial herniation pit, pseudocyst, enostosis, intraosseous ganglion cyst, fibrous dysplasia, stress fracture, avulsion fracture (healing stage), bone infarct, myositis ossificans, brown tumor, and subchondral cyst.
  • Accurate diagnosis and management of these lesions require a basic understanding of their epidemiology, clinical presentations, anatomic distributions, imaging features, differential considerations, and therapeutic options.
  • This in-depth review of 13 potential bone tumor mimics will assist the radiologist in correctly identifying these benign lesions and in avoiding misdiagnosis and related morbidity.
  • [MeSH-major] Bone Diseases / diagnosis. Bone Neoplasms / diagnosis. Magnetic Resonance Imaging
  • [MeSH-minor] Ankle Joint / radiography. Bone Cysts / diagnosis. Bone Cysts / pathology. Bone and Bones / blood supply. Diagnosis, Differential. Femur Neck / pathology. Fibromatosis, Aggressive / diagnosis. Fibrous Dysplasia of Bone / diagnosis. Fractures, Stress / diagnosis. Ganglion Cysts / diagnosis. Humans. Infarction / diagnosis. Myositis Ossificans / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 17484955.001).
  • [ISSN] 0363-0188
  • [Journal-full-title] Current problems in diagnostic radiology
  • [ISO-abbreviation] Curr Probl Diagn Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 48
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47. Bennani L, Amine B, Aktaou S, Hajjaj-Hassouni N: [True intra-articular lipoma in a rheumatoid knee]. Presse Med; 2008 Apr;37(4 Pt 1):610-3
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  • INTRODUCTION: Lipoma is a frequent benign tumor of the soft tissue, but intra-articular locations are rare.
  • She had reported arthritis of the left knee for the past two years; concern about infection led to aspiration of the knee joint, which found inflammatory aseptic fluid, and radiography of the knee was normal.
  • MRI can provide a positive and differential diagnosis, but nonetheless requires histologic confirmation.
  • [MeSH-major] Arthritis, Rheumatoid / complications. Knee Joint / surgery
  • [MeSH-minor] Female. Humans. Lipoma / diagnosis. Lipoma / surgery. Middle Aged. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery. Synovitis / complications

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  • (PMID = 18191369.001).
  • [ISSN] 2213-0276
  • [Journal-full-title] Presse medicale (Paris, France : 1983)
  • [ISO-abbreviation] Presse Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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48. Jundt G, Baumhoer D: [Hereditary bone tumors]. Pathologe; 2010 Oct;31(6):471-6
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  • Familial diseases leading to bone tumor formation are rare.
  • This leads to multiple benign bone tumors, which may undergo secondary malignant transformation (enchondromatosis: enchondromas, multiple hereditary exostoses: osteochondromas) or bone sarcomas, mainly osteosarcomas, such as primary (Li-Fraumeni, Rothmund-Thomson, Werner and Bloom syndromes) or secondary manifestations (retinoblastoma syndrome) of the underlying disease.

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  • (PMID = 20960198.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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49. Ismail BE, Kissel CG, Husain ZS, Entwistle T: Osteochondroma of the distal tibia in an adolescent: a case report. J Foot Ankle Surg; 2008 Nov-Dec;47(6):554-8
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  • Computerized tomography revealed a 2.44 x 4.48-cm bone tumor proximal to the ankle joint, and this was consistent with her complaint of pain and the observed malposition of the distal leg and ankle.
  • Although the radiographic characteristics of the lesion were indicative of osteochondroma, a typically asymptomatic and benign tumor that is usually identified as an incidental finding, the large size and symptoms associated with the lesion described in this article make it rather unusual.
  • In this particular case, excessive bony outgrowth, pain, joint malposition, and pathologic fracture necessitated surgical intervention.
  • The patient was successfully treated with resection of the tumor, after which gradual restoration of the alignment of the distal leg ensued without the need for fibular osteotomy.
  • [MeSH-major] Bone Neoplasms / complications. Bone Neoplasms / diagnosis. Fractures, Bone / diagnosis. Fractures, Bone / etiology. Osteochondroma / complications. Osteochondroma / diagnosis. Tibia / pathology

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  • (PMID = 19239866.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Ares-Rodriguez O, Soldado-Carrera F, Fontecha CG, Aguirre Canyadell M: Synovial hemangioma in the knee of a 10-month-old boy. Arch Orthop Trauma Surg; 2008 Jun;128(6):583-4
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  • Synovial hemangioma is a benign vascular tumor.
  • A delay between debut and diagnosis due to its unspecific symptomatology is common.
  • [MeSH-major] Hemangioma / diagnosis. Knee Joint. Soft Tissue Neoplasms / diagnosis. Synovial Membrane
  • [MeSH-minor] Diagnosis, Differential. Humans. Infant, Newborn. Male

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  • (PMID = 17701190.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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51. Niimi R, Matsumine A, Kusuzaki K, Shintani K, Nakamura T, Kotera H, Murata T, Uchida A: Epithelioid hemangioendothelioma after radiotherapy for congenital hemangioma: a case report. Med Oncol; 2010 Mar;27(1):130-3
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  • At 28 years of age, the patient noticed a large tumor mass with intractable pain at the antero-lateral aspect of the proximal lower leg, and she presented to our hospital.
  • Since microscopic examination of a biopsy specimen showed epithelioid hemangioendothelioma, disarticulation at the knee joint was performed.
  • Although malignant change in a benign vascular tumor is extremely rare, irradiation can induce malignant transformation of a hemangioma.
  • [MeSH-minor] Adult. Disarticulation. Female. Humans. Knee Joint / surgery. Magnetic Resonance Imaging. Pain / etiology. Tibia / diagnostic imaging. Tibia / physiopathology. Tomography, X-Ray Computed. Treatment Outcome


52. Li JM, Yang ZP, Li ZF, Li X, Carter SR: Knee reconstruction with preservation of the meniscus in tibial giant cell tumor. Clin Orthop Relat Res; 2008 Dec;466(12):3101-7
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  • [Title] Knee reconstruction with preservation of the meniscus in tibial giant cell tumor.
  • Giant cell tumor of bone sometimes is an aggressive benign skeletal tumor.
  • Thus, maintaining joint function and achieving adequately wide resection introduces contradictory surgical goals.
  • We reconstructed 13 knees preserving the meniscus and reconstructing the tibial plateau with an iliac plate autograft after resection of a giant cell tumor involving one tibial plateau.
  • While resecting the tumor, the normal anatomic structures of the knee can be preserved or restored in many patients.
  • [MeSH-major] Bone Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Orthopedic Procedures / methods. Reconstructive Surgical Procedures / methods
  • [MeSH-minor] Adult. Bone Transplantation. Female. Humans. Ilium / transplantation. Male. Menisci, Tibial. Middle Aged. Neoplasm Recurrence, Local / epidemiology. Retrospective Studies. Tibia. Transplantation, Autologous. Young Adult

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  • (PMID = 18830792.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2628220
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53. Iatrou IA, Theologie-Lygidakis N, Leventis MD: Case report: desmoplastic fibroma of the mandible in a child presenting with TMJ dysfunction. Eur Arch Paediatr Dent; 2008 Jun;9(2):105-8
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  • BACKGROUND: Desmoplastic fibroma of bone is a rare intraosseous benign but locally aggressive tumor of connective tissue origin.
  • Clinical and radiological examination revealed a tumor-like lesion of the mandible extending into the soft tissues, which on biopsy proved to be a desmoplastic fibroma.
  • Extended surgical removal of the tumor, with wide margins, proved to be the appropriate treatment.
  • [MeSH-major] Fibroma, Desmoplastic / complications. Mandibular Neoplasms / complications. Temporomandibular Joint Disorders / etiology

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  • (PMID = 18534181.001).
  • [ISSN] 1818-6300
  • [Journal-full-title] European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
  • [ISO-abbreviation] Eur Arch Paediatr Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
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54. Al Yami A, Griffin AM, Ferguson PC, Catton CN, Chung PW, Bell RS, Wunder JS, O'Sullivan B: Positive surgical margins in soft tissue sarcoma treated with preoperative radiation: is a postoperative boost necessary? Int J Radiat Oncol Biol Phys; 2010 Jul 15;77(4):1191-7
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  • There was no difference in baseline tumor characteristics between the two groups.
  • Given that higher radiation doses placed patients at greater risk for late complications such as fracture, fibrosis, edema, and joint stiffness, judicious avoidance of the postoperative boost while maintaining an equivalent rate of local control can reduce the risk of these difficult-to-treat morbidities.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Amputation. Female. Histiocytoma, Benign Fibrous / pathology. Histiocytoma, Benign Fibrous / prevention & control. Histiocytoma, Benign Fibrous / radiotherapy. Histiocytoma, Benign Fibrous / surgery. Humans. Leiomyosarcoma / pathology. Leiomyosarcoma / prevention & control. Leiomyosarcoma / radiotherapy. Leiomyosarcoma / surgery. Limb Salvage. Liposarcoma / pathology. Liposarcoma / prevention & control. Liposarcoma / radiotherapy. Liposarcoma / surgery. Male. Middle Aged. Neoplasm Recurrence, Local / prevention & control. Neoplasm, Residual. Postoperative Care. Radiotherapy Dosage. Retreatment. Young Adult

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • [CommentIn] Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):959; author reply 959-60 [21621120.001]
  • (PMID = 20056340.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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55. Al-Ahwal MS, Sawan AS, Zimmo SK: Malignant eccrine poroma. Saudi Med J; 2005 May;26(5):859-61
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  • Benign eccrine poroma arises from the intraepidermal portion of the eccrine gland duct.
  • We report a 44-year-old male patient who presented primarily with a lesion diagnostic of benign eccrine poroma of the right foot sole with no clear evidence of malignancy, which was incompletely excised, followed 5 months later by local recurrence, ulceration, occasional bleeding and right inguinal lymphadenopathy.
  • Incomplete excision of the primary tumor as well as excision of a skin lesion on the right knee joint revealed malignant eccrine poroma with aggressive histology, lymphovascular and perineural invasion.
  • This tumor might be malignant at the first presentation, which was not confirmed histopathologically considering the short duration of only 5 months for malignant transformation.
  • [MeSH-major] Foot Diseases / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • [CommentIn] Saudi Med J. 2005 Oct;26(10):1665; author reply 1665 [16228085.001]
  • (PMID = 15951884.001).
  • [ISSN] 0379-5284
  • [Journal-full-title] Saudi medical journal
  • [ISO-abbreviation] Saudi Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Saudi Arabia
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56. Mortazavi SM, Wenger D, Asadollahi S, Shariat Torbaghan S, Unni KK, Saberi S: Periosteal osteoblastoma: report of a case with a rare histopathologic presentation and review of the literature. Skeletal Radiol; 2007 Mar;36(3):259-64
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  • Osteoblastoma is an uncommon benign bone tumor most commonly located in the vertebral column or metaphysis of a long bone.
  • Although extremely unusual, the presence of cartilage does not necessarily exclude the diagnosis of osteoblastoma.
  • [MeSH-major] Bone Neoplasms / diagnosis. Knee Joint / pathology. Osteoblastoma / diagnosis. Periosteum / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Tomography, Emission-Computed. Tomography, X-Ray Computed

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  • (PMID = 16868789.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 29
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57. Slotcavage RL, Dickson BC, Ogilvie CM: Chondromyxoid fibroma involving the metacarpophalangeal joint. Orthopedics; 2009 Apr;32(4)
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  • [Title] Chondromyxoid fibroma involving the metacarpophalangeal joint.
  • Chondromyxoid fibroma is a rare benign bony tumor classically occurring in the metaphyseal region of the long bones surrounding the knee, but also found with relative frequency in other long bones, the pelvis, ribs, and small foot bones.
  • The tumor is considered a physeal plate remnant and may involve the epiphysis, diaphysis, or both along with its metaphyseal origin.
  • We report a case of histopathologically confirmed chondromyxoid fibroma involving a metacarpal, proximal phalanx, and synovial tissues of the metacarpophalangeal joint.
  • A 29-year-old woman presented with pain, weakness, and a mass of the right ring finger metacarpophalangeal joint that had persisted since prior surgery to remove an extraosseous chondroma.
  • Histologic examination revealed an unusual chondromyxoid fibroma with joint involvement.
  • This benign, curable lesion should be included in the differential diagnosis of a bony lesion, even when a joint and adjacent bones are involved.
  • [MeSH-major] Bone Neoplasms / radiography. Chondroma / radiography. Fibroma / radiography. Metacarpophalangeal Joint / radiography

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  • (PMID = 19388607.001).
  • [ISSN] 1938-2367
  • [Journal-full-title] Orthopedics
  • [ISO-abbreviation] Orthopedics
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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58. Weber K, Damron TA, Frassica FJ, Sim FH: Malignant bone tumors. Instr Course Lect; 2008;57:673-88
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  • The primary symptom of a patient with a malignant bone tumor is pain, which often occurs at rest or at night.
  • There are also characteristic findings on physical examination such as swelling or decreased joint range of motion.
  • Patients with a likely malignancy require thorough staging to determine the extent of disease and a well-planned biopsy for accurate diagnosis.
  • Knowledge of specific tumor characteristics and treatment options for osteosarcoma, Ewing's sarcoma, chondrosarcoma, malignant fibrous histiocytoma, chordoma, and adamantinoma is important.
  • Secondary sarcomas can occur in previously benign bone lesions and require aggressive treatment.
  • [MeSH-minor] Global Health. Humans. Morbidity. Neoplasm Staging / methods. Prognosis

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  • (PMID = 18399615.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Number-of-references] 42
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59. Kim TK, Kim KH, Kim CH, Shin SW, Kwon JY, Kim HK, Baik SW: Percutaneous vertebroplasty and facet joint block. J Korean Med Sci; 2005 Dec;20(6):1023-8
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  • [Title] Percutaneous vertebroplasty and facet joint block.
  • It is surprising that about 24% of patients with benign osteoporotic vertebral fracture die within a year from respiratory infection and urinary tract infection because of coughing and voiding difficulties, depending on the sites of compression fractures.
  • To confirm the most painful level among the multiple fracture sites, physical examination after facet joint block under the fluoroscope was the most reliable method.
  • The mean changes of numeric rating scale scores, Oswestry Disability Index except sex life, and Karnofsky performance status were -72.00, -83.50 and +60.62% in the osteoporosis group and -51.89, -45.02, and 69.03% in the tumor group.
  • PVP with facet joint block is a profitable method for the vertebral compression fracture because of low risk and short duration of procedure with a high chance to result in pain relief and early mobilization.
  • [MeSH-minor] Aged. Bone Cements / therapeutic use. Female. Follow-Up Studies. Humans. Injections, Spinal. Male. Middle Aged. Minimally Invasive Surgical Procedures. Nerve Block. Orthopedic Procedures. Pain / physiopathology. Pain / surgery. Zygapophyseal Joint

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  • (PMID = 16361816.001).
  • [ISSN] 1011-8934
  • [Journal-full-title] Journal of Korean medical science
  • [ISO-abbreviation] J. Korean Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Bone Cements
  • [Other-IDs] NLM/ PMC2779303
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60. Eckardt AM, Barth EL, Berten J, Gellrich NC: Pediatric mandibular resection and reconstruction: long-term results with autogenous rib grafts. Craniomaxillofac Trauma Reconstr; 2010 Mar;3(1):25-32
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  • Reconstruction of mandibular defects following tumor resection in infants is a particular challenge.
  • Although autogenous rib grafts have no relevance in the restoration of mandibular bone defects occurring after ablative tumor surgery due to limited bone stock and the availability of other donor areas, they are a useful surgical alternative following tumor surgery in infants.
  • We here report on a 2, 5, 8, and 15-year follow-up of four children who were diagnosed with benign tumors of the mandible with osseous destruction at the age of 4, 6, 15, and 18 months, respectively.
  • Histologic diagnoses were melanotic neuroectodermal tumor (n = 2), hemangioendothelioma of the mandible (n = 1), and ameloblastoma (n = 1).

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  • (PMID = 22110815.001).
  • [ISSN] 1943-3883
  • [Journal-full-title] Craniomaxillofacial trauma & reconstruction
  • [ISO-abbreviation] Craniomaxillofac Trauma Reconstr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3052664
  • [Keywords] NOTNLM ; Mandibular reconstruction / bone graft / facial growth / pediatric maxillofacial tumor / rib graft
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61. Jobke B, Werner M, Jundt G, Ostertag H, Freyschmidt J: Protracted disseminated skeletal metastases from angiosarcoma of the spleen. Clin Exp Metastasis; 2010 Feb;27(2):117-22
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  • The 55-years-old patient presented in this case report had a disease-free 4 years interval between splenectomy after primary angiosarcoma of the spleen and an unusual skeletal metastatic pattern mimicking benign angiomatosis.
  • Despite lacking radiographic evidence for a highly aggressive osseous process, the histopathological resemblance of the bone biopsy with the primary tumor manifestation and the fulminant course of disease after onset of disseminated osseous spread confirmed the malignant character of the vascular tumor.

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  • (PMID = 20174857.001).
  • [ISSN] 1573-7276
  • [Journal-full-title] Clinical & experimental metastasis
  • [ISO-abbreviation] Clin. Exp. Metastasis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 21
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62. Admassie D, Bura J: Two cases of interathoracic pathologies presented as secondory hypertrophic osteoarthopathy. Ethiop Med J; 2006 Apr;44(2):191-4
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  • The vast majority of cases of Hypertrophic osteoarthropathy are associated with intra thoracic neoplasms mainly broncogenic cancer and benign fibrous tumor.
  • The first is a 50-years-old male who came with complaints of significant weight loss, chest symptoms and multiple upper extremities joint pain.
  • The second case was a 44 years old female who presented similarly with chest symptoms, joint and bone pain limited to lower extremities bilaterally.
  • The first patient with bronchogenic carcinoma, bronchoscopy with biopsy conform the diagnosis.
  • The second patient was operated and the operative biopsy result was consistent with benign pleural fibroma.

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  • (PMID = 17447383.001).
  • [ISSN] 0014-1755
  • [Journal-full-title] Ethiopian medical journal
  • [ISO-abbreviation] Ethiop. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ethiopia
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63. Camargo OP, Croci AT, Oliveira CR, Baptista AM, Caiero MT: Functional and radiographic evaluation of 214 aggressive benign bone lesions treated with curettage, cauterization, and cementation: 24 years of follow-up. Clinics (Sao Paulo); 2005 Dec;60(6):439-44
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  • [Title] Functional and radiographic evaluation of 214 aggressive benign bone lesions treated with curettage, cauterization, and cementation: 24 years of follow-up.
  • PURPOSE: Treatment with curettage, cauterization, and methylmethacrylate of aggressive benign bone lesions is a method now widely accepted in most orthopedic oncology centers.
  • The objective of this paper is to present a functional and radiographic evaluation of 214 patients presenting with aggressive benign bone lesions treated with curettage, cauterization, and methylmethacrylate from 1974 to 1998, with some of them having 24 years of follow-up.
  • These patients were clinically and radiographically evaluated for the incidence of late osteoarthrosis, range of motion, and pain in the involved joint.
  • All cases involved aggressive benign lesions.
  • The patients were evaluated according to the Musculoskeletal Tumor Society Score (MSTS) functional evaluation system, and the complications are described.

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  • (PMID = 16358131.001).
  • [ISSN] 1807-5932
  • [Journal-full-title] Clinics (São Paulo, Brazil)
  • [ISO-abbreviation] Clinics (Sao Paulo)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Chemical-registry-number] 0 / Bone Cements; 196OC77688 / Methylmethacrylate
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64. Kalish LH, Ng T, Kalnins I, Da Cruz MJ: Pseudogout mimicking an infratemporal fossa tumor. Head Neck; 2010 Jan;32(1):127-32
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  • [Title] Pseudogout mimicking an infratemporal fossa tumor.
  • METHODS AND RESULTS: We present a case of a 71-year-old woman who presented with worsening facial pain, trismus, and a large mass in her infratemporal fossa with minimal associated temporomandibular joint destruction.
  • CONCLUSION: The clinical and radiological features of patients with tophaceous pseudogout frequently mimic those of a benign or malignant neoplasm of the infratemporal fossa, often resulting in more radical surgery.
  • [MeSH-major] Chondrocalcinosis / diagnosis. Chondrocalcinosis / surgery. Skull Base Neoplasms / diagnosis. Skull Base Neoplasms / surgery. Temporal Bone / surgery
  • [MeSH-minor] Aged. Diagnosis, Differential. Facial Pain / etiology. Female. Humans. Otorhinolaryngologic Surgical Procedures / methods. Temporomandibular Joint / pathology. Treatment Outcome. Trismus / etiology

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  • (PMID = 19283846.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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65. Konya D, Ozgen S, Kurtkaya O, Pamir NM: Lumbar spinal angiolipoma: case report and review of the literature. Eur Spine J; 2006 Jun;15(6):1025-8
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  • Spinal angiolipomas are extremely rare benign tumors composed of mature lipomatous and angiomatous elements.
  • Laminectomy was performed, and an extradural tumor was totally excised.
  • This rare clinical entity must be considered in the differential diagnosis for any spinal epidural lesion.

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  • (PMID = 16172903.001).
  • [ISSN] 0940-6719
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 16
  • [Other-IDs] NLM/ PMC3489428
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66. Bhandari A, Patel PR, Patel MP: Extranodal Rosai-Dorfman disease with multiple spinal lesions: a rare presentation. Surg Neurol; 2006 Mar;65(3):308-11
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  • Its resemblance with meningiomas both clinically and radiologically makes its diagnosis all the more difficult.
  • CASE DESCRIPTION: A 23-year-old woman presented with quadriparesis and incontinence of urine and stool with a history of being operated on twice for dorsal spine tumor.
  • On examination she had hypoesthesia below the C6 vertebra with anesthesia below D3, and absent joint position and vibration sensations.
  • It is a benign lymphohistiocytic proliferative condition of unknown etiology.
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Image Enhancement. Magnetic Resonance Imaging. Muscle Weakness / etiology. Neurologic Examination. Recurrence. Reoperation


67. Song JW, DU LL, Zhao XW, Jing JX, Han CZ, Cui Y, Liu JW, Hao HL, Wang ZG, Mi ZG: [Expression and clinical significance of nuclear matrix protein 22 and cytokeratin 18 in transitional cell carcinoma of the bladder]. Zhonghua Zhong Liu Za Zhi; 2009 Apr;31(4):274-7
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  • METHODS: Urinary NMP22 and CK18 levels of 293 patients with transitional cell carcinoma of the bladder, 400 patients with non-transitional cell carcinoma of the bladder, and 105 bladder benign disease were analysed by enzyme-linked-immunosorbent assay (ELISA).
  • RESULTS: The levels of urinary NMP22 and CK18 in the patients with transitional cell carcinoma of the bladder (M = 17.3 U/ml, M(CK18) = 484.2 U/L) were significantly higher than those in the non-transitional cell carcinoma of the bladder (M = 6.8 U/ml, M(CK18) = 156.0 U/L) and the benign disease group (M(NMP22) = 2.3 U/ml, M(CK18) = 66.6 U/L) (P < 0.001).
  • The joint sensitivity of the two markers was 91.7%.
  • CONCLUSION: NMP22 and CK18 are useful tumor marker for diagnosis of transitional cell carcinoma of the bladder and for monitoring the state of illness.
  • The joint use of the two markers can improve the sensitivity of cancer detection.
  • NMP22 and CK18 may become a new class of tumor markers, and to be the basis for development of a new assay with an increased efficacy for the detection and treatment of bladder cancer.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / urine. Carcinoma, Renal Cell / urine. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local / urine. Neoplasm Staging. Prognosis. Sensitivity and Specificity. Young Adult

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  • (PMID = 19615282.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-18; 0 / Nuclear Proteins; 0 / nuclear matrix protein 22
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68. Harty L, Veale DJ: How early should psoriatic arthritis be treated with a TNF-blocker? Curr Opin Rheumatol; 2010 Jul;22(4):393-6
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  • The skin manifestations may be mild or patchy and often precede the joint inflammation.
  • Joint erosions, however, may occur within the first 2 years in up to half of PsA patients and an erosion rate of 11% per annum has been reported suggesting it is not a benign disease as it was once regarded.
  • In cases of more widespread joint involvement systemic therapy with disease-modifying antirheumatic drugs (DMARDs) such as methotrexate may be required and in the case of extra-articular or spinal disease, in which DMARDs have failed to show efficacy, biologic therapy may be highly effective.
  • [MeSH-major] Antibodies, Monoclonal / therapeutic use. Arthritis, Psoriatic / therapy. Receptors, Tumor Necrosis Factor / antagonists & inhibitors
  • [MeSH-minor] Antirheumatic Agents / therapeutic use. Humans. Tumor Necrosis Factor-alpha / therapeutic use

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  • (PMID = 20520552.001).
  • [ISSN] 1531-6963
  • [Journal-full-title] Current opinion in rheumatology
  • [ISO-abbreviation] Curr Opin Rheumatol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antirheumatic Agents; 0 / Receptors, Tumor Necrosis Factor; 0 / Tumor Necrosis Factor-alpha
  • [Number-of-references] 23
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69. Toomayan GA, Robertson F, Major NM, Brigman BE: Upper extremity compartmental anatomy: clinical relevance to radiologists. Skeletal Radiol; 2006 Apr;35(4):195-201
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  • The Musculoskeletal Tumor Society (MSTS) staging system is used by the surgeon to determine appropriate surgical management, assess prognosis, and communicate with other healthcare providers.
  • Case examples are presented to illustrate the importance of compartmental anatomy in the management of benign and malignant upper extremity tumors.

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  • (PMID = 16489465.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 22
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70. Arai E, Nishida Y, Tsukushi S, Sugiura H, Ishiguro N: Intramuscular granular cell tumor in the lower extremities. Clin Orthop Relat Res; 2010 May;468(5):1384-9
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  • [Title] Intramuscular granular cell tumor in the lower extremities.
  • Granular cell tumors are uncommon but typically histologically benign neoplasms that occasionally behave as malignant tumors.
  • Differentiation of benign granular cell tumors from malignant counterparts with radiographic and/or histologic analysis is crucial for physicians.
  • All tumors had been histologically diagnosed as benign and were resected with a wide surgical margin.
  • The histologic criteria described by Fanburg-Smith et al. can differentiate malignant granular cell tumors from benign tumors.
  • [MeSH-major] Granular Cell Tumor / diagnosis. Leg
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Prognosis. Retrospective Studies. Time Factors

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  • (PMID = 19760336.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2853648
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71. Abdel MP, Papagelopoulos PJ, Morrey ME, Wenger DE, Rose PS, Sim FH: Surgical management of 121 benign proximal fibula tumors. Clin Orthop Relat Res; 2010 Nov;468(11):3056-62
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  • [Title] Surgical management of 121 benign proximal fibula tumors.
  • Patients with aggressive benign tumors in the proximal fibula may require en bloc resection.
  • QUESTIONS/PURPOSES: We therefore analyzed the incidence of peroneal nerve palsy, knee stability, and local recurrence following surgical treatment of benign proximal fibula tumors.
  • METHODS: We retrospectively reviewed the charts of 120 patients (121 tumors) with histologically confirmed aggressive benign tumors of the proximal fibula.
  • The most common diagnosis was osteochondroma (38%) followed by giant cell tumor (19%).
  • [MeSH-minor] Adolescent. Adult. Child. Child, Preschool. Curettage / adverse effects. Female. Humans. Joint Instability / etiology. Joint Instability / physiopathology. Knee Joint / physiopathology. Male. Middle Aged. Neoplasm Recurrence, Local. Osteotomy / adverse effects. Peroneal Neuropathies / etiology. Range of Motion, Articular. Retrospective Studies. Surgical Wound Dehiscence / etiology. Time Factors. Treatment Outcome. Venous Thrombosis / etiology. Young Adult

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  • (PMID = 20625947.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2947668
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72. Rebbeck TR, Rennert H, Walker AH, Panossian S, Tran T, Walker K, Spangler E, Patacsil-Coomes M, Sachdeva R, Wein AJ, Malkowicz SB, Zeigler-Johnson C: Joint effects of inflammation and androgen metabolism on prostate cancer severity. Int J Cancer; 2008 Sep 15;123(6):1385-9
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  • [Title] Joint effects of inflammation and androgen metabolism on prostate cancer severity.
  • These pathways are not independent, and may act together in prostate cancer etiology: androgens promote both inflammatory processes and serve as mitogens in prostate tumor growth.
  • To explore the possible joint effects of these pathways in prostate cancer severity, we studied 1,090 Caucasian prostate cancer cases to evaluate whether tumor severity is influenced by a history of benign prostatic hyperplasia (BPH) interacting with genotypes involved in inflammation or androgen metabolism including MSR1, RNASEL, AR, CYP3A4, CYP3A43, CYP3A5 and SRD5A2.
  • After considering the potential for false positive associations, the only remaining significant associations involved CYP3A43 P340A genotypes and history of BPH on both Gleason grade (interaction p-value = 0.026) and tumor stage (interaction p-value = 0.017).

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  • [Copyright] Copyright 2008 Wiley-Liss, Inc.
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  • (PMID = 18566991.001).
  • [ISSN] 1097-0215
  • [Journal-full-title] International journal of cancer
  • [ISO-abbreviation] Int. J. Cancer
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / R01 CA085074-01; United States / NIEHS NIH HHS / ES / R29-ES08031; United States / NCI NIH HHS / CA / CA085074-01; United States / NCI NIH HHS / CA / P50-CA105641; United States / NCI NIH HHS / CA / R01 CA085074; United States / NCI NIH HHS / CA / P50 CA105641; United States / NCI NIH HHS / CA / R01-CA85074
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Androgens; EC 1.14.13.67 / CYP3A4 protein, human; EC 1.14.14.1 / Cytochrome P-450 CYP3A
  • [Other-IDs] NLM/ NIHMS58389; NLM/ PMC2700293
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73. Hirn M, de Silva U, Sidharthan S, Grimer RJ, Abudu A, Tillman RM, Carter SR: Bone defects following curettage do not necessarily need augmentation. Acta Orthop; 2009 Feb;80(1):4-8
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  • BACKGROUND AND PURPOSE: The natural pattern of bone healing in large bony defects following curettage alone as treatment of benign bone tumors around the knee is not well reported.
  • PATIENTS AND METHODS: 146 patients with over 18 months of follow-up who underwent curettage without bone substitute filling or bone grafting for a benign tumor in the distal femur or upper tibia were included.
  • The risk of subsequent fracture or the late development of osteoarthritis was strongly related to the size of the cyst at diagnosis, with cysts of > 60 cm(3) (about 5 cm in diameter) having a much higher incidence of complications.

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  • (PMID = 19234881.001).
  • [ISSN] 1745-3682
  • [Journal-full-title] Acta orthopaedica
  • [ISO-abbreviation] Acta Orthop
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Sweden
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  • [Other-IDs] NLM/ PMC2823228
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74. Couldwell WT, Cannon-Albright L: A heritable predisposition to pituitary tumors. Pituitary; 2010 Jun;13(2):130-7
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  • We analyzed the Utah Population Data Base (UPDB), a resource combining a computerized genealogy of the Utah population with a statewide tumor registry, to investigate familial clustering of pituitary tumors.
  • We analyzed the genetic relationships among 741 individuals diagnosed with benign or malignant pituitary tumors who had Utah genealogy data.
  • The average pairwise relatedness of pituitary tumor cases was significantly higher than expected, even when close relationships were ignored.

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  • (PMID = 20012699.001).
  • [ISSN] 1573-7403
  • [Journal-full-title] Pituitary
  • [ISO-abbreviation] Pituitary
  • [Language] ENG
  • [Grant] United States / NLM NIH HHS / LM / R01 LM009331; United States / NCI NIH HHS / PC / N01-PC-35141; United States / NCI NIH HHS / CA / N01PC35141; United States / NCI NIH HHS / PC / N01 PC035141; United States / NLM NIH HHS / LM / LM009331-03; United States / NCI NIH HHS / CA / P30 CA042014; United States / NLM NIH HHS / LM / LM009331; United States / NLM NIH HHS / LM / R01 LM009331-03
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS172139; NLM/ PMC2863058
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75. Murata H, Horie N, Matsui T, Akai T, Ueda H, Oshima Y, Konishi E, Kubo T: Clinical usefulness of thallium-201 scintigraphy and magnetic resonance imaging in the diagnosis of chondromyxoid fibroma. Ann Nucl Med; 2008 Apr;22(3):221-4
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  • [Title] Clinical usefulness of thallium-201 scintigraphy and magnetic resonance imaging in the diagnosis of chondromyxoid fibroma.
  • Chondromyxoid fibroma (CMF) is a benign bone tumor.
  • However, it is sometimes difficult to distinguish this tumor from chondrosarcoma.
  • The tumor was diagnosed as CMF by open biopsy.
  • Contrast-enhanced MR imaging and thallium-201 scintigraphy may be useful to distinguish CMF from benign bone tumors or chondrosarcoma.
  • [MeSH-minor] Adolescent. Biopsy. Citrates / pharmacokinetics. Contrast Media / pharmacokinetics. Diagnosis, Differential. Diphosphonates / pharmacokinetics. Fibroma / radiography. Fibroma / radionuclide imaging. Fibula / pathology. Gadolinium DTPA / pharmacokinetics. Gallium / pharmacokinetics. Humans. Knee Joint / pathology. Knee Joint / radiography. Knee Joint / radionuclide imaging. Knee Joint / surgery. Magnetic Resonance Imaging. Male. Osteolysis / radiography. Radionuclide Imaging. Radiopharmaceuticals / pharmacokinetics. Technetium Compounds / pharmacokinetics

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  • (PMID = 18498038.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Citrates; 0 / Contrast Media; 0 / Diphosphonates; 0 / Radiopharmaceuticals; 0 / Technetium Compounds; 0 / Thallium Radioisotopes; 27905-02-8 / gallium citrate; 8V3FGC4J77 / technetium Tc 99m diphosphonate; CH46OC8YV4 / Gallium; K2I13DR72L / Gadolinium DTPA
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76. Sidani CA, Karam AR, Bruce JH, Sklar E: Osteoblastoma of the frontal sinuses presenting with headache and blurred vision: case report and review of the literature. J Radiol Case Rep; 2010;4(6):1-7
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  • Osteoblastoma is a rare benign bone tumor that usually arises in the vertebral column and long bones of young adults.

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  • (PMID = 22470734.001).
  • [ISSN] 1943-0922
  • [Journal-full-title] Journal of radiology case reports
  • [ISO-abbreviation] J Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3303412
  • [Keywords] NOTNLM ; Frontal sinus / exophthalmos / osteoblastoma
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77. Wang W, Kong L, Dong R, Zhao H, Ma Y, Lu Y: Osteoma in the upper cervical spine with spinal cord compression. Eur Spine J; 2006 Oct;15 Suppl 5:616-20
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  • Osteoma is a common benign tumor.
  • On systemic examination and rontgenographic study, these two cases were found to have bone tumor in the upper cervical canal.
  • The pathological study demonstrated a diagnosis of osteoma.

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  • (PMID = 16649125.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
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78. Nthumba PM: Marjolin's ulcers: theories, prognostic factors and their peculiarities in spina bifida patients. World J Surg Oncol; 2010;8:108
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  • RESULTS: The two ulcers appeared clinically benign: one was a deep ulcer, while the other was shallow; both had normal, benign-appearing edges, and a foul smelling discharge.
  • Poor prognostic features include pressure ulcer carcinomas, lesions and location in the lower limbs/trunks, all present in the two patients making their prognosis dim: this is despite the surgical margins being clear of tumor.
  • Benign appearance, induration and presence of multiple communicating sinuses are features that have not been previously described as presenting features of pressure ulcers carcinomas.

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  • (PMID = 21129225.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3014936
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79. Jakowski JD, Wakely PE Jr, Jimenez RE: An uncommon type of adrenal incidentaloma: a case report of a schwannoma of the adrenal medulla with cytological, histological, and ultrastructural correlation. Ann Diagn Pathol; 2008 Oct;12(5):356-61
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  • Benign nerve sheath tumors of the adrenal gland are an extremely uncommon cause of an incidentaloma.
  • We report a case of a schwannoma of the adrenal medulla in an asymptomatic 51-year-old woman, which was discovered incidentally on a computed tomography scan after routine workup for her degenerative joint diseases of the lumbar spine.
  • Because of the large size and unknown biologic nature of the tumor by clinical and radiographic studies alone, an adrenalectomy was performed.
  • The gross specimen featured a well-circumscribed medullary based tumor with cystic degeneration.
  • The diagnosis of a nerve sheath tumor was based on classic histological findings, supported by S-100 positivity, and ultrastructurally by the finding of typical Schwann cells.
  • The cytological diagnosis from the fine-needle aspiration biopsy material obtained at the time of gross examination was much more challenging on retrospective review.
  • A review of the histogenesis and differential diagnosis of this common nerve sheath tumor in this unusual location is discussed.
  • [MeSH-minor] Adrenalectomy. Biomarkers, Tumor / analysis. Biopsy. Female. Humans. Incidental Findings. Middle Aged. S100 Proteins / analysis. Schwann Cells / ultrastructure. Tomography, X-Ray Computed

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  • (PMID = 18774499.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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80. Morris LG, Rihani J, Lebowitz RA, Wang BY: Chondromyxoid fibroma of sphenoid sinus with unusual calcifications: case report with literature review. Head Neck Pathol; 2009 Jun;3(2):169-73
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  • Chondromyxoid fibroma (CMF) is a rare benign primary tumor which usually affects the metaphyses of the long bone of the lower extremities in childhood and young adults.
  • The tumor mass showed calcifications on images and histology.

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  • (PMID = 19644549.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
  • [Keywords] NOTNLM ; Calcification / Chondromyxoid fibroma / Sphenoid sinus
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81. Schindler OS, Cannon SR, Briggs TW, Blunn GW: Composite ceramic bone graft substitute in the treatment of locally aggressive benign bone tumours. J Orthop Surg (Hong Kong); 2008 Apr;16(1):66-74
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  • [Title] Composite ceramic bone graft substitute in the treatment of locally aggressive benign bone tumours.
  • PURPOSE: To report the use of a composite ceramic bone graft substitute containing calcium sulphate and hydroxyapatite (HA) in the treatment of large expansive osteolytic benign bone tumours.
  • Range of movement, Musculoskeletal Tumor Society Rating Score (MTSRS), and haematological and blood biochemical parameters were measured.
  • Tumour recurrence remains a major concern especially in young patients, as revision invariably requires removal of additional bone, potentially compromising joint integrity.
  • [MeSH-minor] Adolescent. Adult. Child. Female. Femoral Neoplasms / surgery. Giant Cell Tumor of Bone / surgery. Humans. Male. Middle Aged. Tibia / surgery

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  • (PMID = 18453663.001).
  • [ISSN] 1022-5536
  • [Journal-full-title] Journal of orthopaedic surgery (Hong Kong)
  • [ISO-abbreviation] J Orthop Surg (Hong Kong)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Bone Substitutes; 91D9GV0Z28 / Durapatite
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82. Bruns J, Yazigee O, Habermann CR: [Pigmented villo-nodular synovitis and teno-synovial giant-cell tumors]]. Z Orthop Unfall; 2008 Sep-Oct;146(5):663-75; quiz 676-80
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  • Regarding PVS the knee joint is the most often involved joint and TSGCT are mostly located in the tendon-sheaths of fingers.
  • Optimal diagnosis includes an X-ray of the involved structure and a MRI.
  • For PVS optimal therapy is a complete synovectomy, whereas, in TSGCT tumors resection of the tumor itself within marginal margins is sufficient.
  • The prognosis of the mostly benign disease depends on the extent of the disease, the involved structure, additional bony involvement and still existing degenerative changes.
  • In contrast, PVS in the hip regularly is followed by a secondary osteoarthrosis, in other joints degenerative changes are depending on the still existing changes at the date of diagnosis.
  • [MeSH-major] Arthroplasty / methods. Giant Cell Tumors / diagnosis. Giant Cell Tumors / surgery. Soft Tissue Neoplasms / diagnosis. Soft Tissue Neoplasms / surgery. Synovitis, Pigmented Villonodular / diagnosis. Synovitis, Pigmented Villonodular / surgery

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  • (PMID = 18949685.001).
  • [ISSN] 1864-6697
  • [Journal-full-title] Zeitschrift für Orthopädie und Unfallchirurgie
  • [ISO-abbreviation] Z Orthop Unfall
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 59
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83. Roeder F, Timke C, Zwicker F, Thieke C, Bischof M, Debus J, Huber PE: Intensity modulated radiotherapy (IMRT) in benign giant cell tumors--a single institution case series and a short review of the literature. Radiat Oncol; 2010;5:18
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  • [Title] Intensity modulated radiotherapy (IMRT) in benign giant cell tumors--a single institution case series and a short review of the literature.
  • PATIENTS AND METHODS: From 2000 and 2006 a total of five patients with histologically proven benign giant cell tumors have been treated with IMRT in our institution.
  • The tumor was located in the sacral region in four and in the sphenoid sinus in one patient.
  • We found no substantial tumor shrinkage after radiotherapy but in two patients morphological signs of extensive tumor necrosis were present on MRI scans.
  • [MeSH-major] Giant Cell Tumor of Bone / radiotherapy. Radiotherapy, Intensity-Modulated

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  • (PMID = 20187955.001).
  • [ISSN] 1748-717X
  • [Journal-full-title] Radiation oncology (London, England)
  • [ISO-abbreviation] Radiat Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 31
  • [Other-IDs] NLM/ PMC2845594
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84. Oliveira RC, Marques KD, Mendonça AR, Mendonça EF, Silva MR, Batista AC, Ribeiro-Rotta RF: Chondrosarcoma of the temporomandibular joint: a case report in a child. J Orofac Pain; 2009;23(3):275-81
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  • [Title] Chondrosarcoma of the temporomandibular joint: a case report in a child.
  • This article reports a rare case of a temporomandibular joint (TMJ) chondrosarcoma in a child.
  • Chondrosarcoma is a malignant cartilaginous neoplasm that resembles synovial chondromatosis.
  • Microscopic findings showed a tumor exhibiting cartilaginous tissue proliferation with cellular pleomorphism, nuclear hyperchromasia, and mixoid changes in the matrix.
  • It is concluded that cartilaginous lesions in the jaws must be regarded with suspicion, since benign and malignant lesions may show similar clinical features.
  • [MeSH-major] Chondrosarcoma / pathology. Temporomandibular Joint Disorders / pathology
  • [MeSH-minor] Child. Cyclin B / analysis. Cyclin B1. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Ki-67 Antigen / analysis. Mandibular Condyle / pathology. Temporomandibular Joint / pathology


85. Puhaindran ME, Healey JH, Athanasian EA: Single ray amputation for tumors of the hand. Clin Orthop Relat Res; 2010 May;468(5):1390-5
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  • The role of this procedure in the management of aggressive benign or malignant hand tumors has been described only in case reports and small case series.
  • The other was treated with radiotherapy alone, as local tumor control would have required a hand amputation.
  • Functional assessment based on the Musculoskeletal Tumor Society staging system showed an average of 27.5 (range, 21-30).
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Retrospective Studies. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 19655212.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2853661
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86. Maheshwari AV, Jain AK, Dhammi IK: Extraskeletal paraarticular osteochondroma of the knee--a case report and tumor overview. Knee; 2006 Oct;13(5):411-4
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  • [Title] Extraskeletal paraarticular osteochondroma of the knee--a case report and tumor overview.
  • Extraskeletal paraarticular osteochondromas are rather unusual osteocartilaginous lesions that arise in the soft tissues adjacent to the joint with no bony or joint continuity.
  • This diagnosis should be considered with the demonstration of a well-circumscribed extraskeletal mineralized mass without any direct continuity with adjacent bone or joint.
  • However, as with other lesions, clinicoradiographic features with histological correlation clinch the diagnosis.
  • We present here such an infrapatellar lesion and discuss criteria helpful in distinguishing these benign lesions from other morphological similar lesions.
  • [MeSH-major] Knee / surgery. Osteochondroma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 16837200.001).
  • [ISSN] 0968-0160
  • [Journal-full-title] The Knee
  • [ISO-abbreviation] Knee
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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87. Boriani S, Bandiera S, Donthineni R, Amendola L, Cappuccio M, De Iure F, Gasbarrini A: Morbidity of en bloc resections in the spine. Eur Spine J; 2010 Feb;19(2):231-41
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  • The study was set up to correlate diagnosis, staging and treatment with the outcome.
  • Oncological and functional results were recorded for all patients at periodic, diagnosis-related controls, until death or the latest follow-up examination (from 0 to 211 months, median 47 months, 25th-75th percentile 22-85 months).
  • Of the 35 patients with a recurrent or contaminated tumor, 16 (45.7%) suffered at least one complication; by contrast, complications arose in 31 (31.3%) of the 99 patients who had had no previous treatment and who underwent the whole of their treatment in the same center (P = 0.125).
  • Re-operations were mostly due to tumor recurrences, but also to hardware failures, wound dehiscence, hematomas and aortic dissection.
  • En bloc resection is able to improve the prognosis of aggressive benign and low-grade malignant tumors in the spine; however, complications are not rare and possibly fatal.
  • [MeSH-minor] Adult. Aged. Aortic Rupture / mortality. Equipment Failure. Female. Humans. Male. Middle Aged. Mortality. Neoplasm Recurrence, Local / mortality. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Outcome Assessment (Health Care). Radiotherapy / adverse effects. Reoperation / mortality. Retrospective Studies. Surgical Wound Dehiscence / mortality. Surgical Wound Infection / mortality. Treatment Outcome

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  • (PMID = 19690899.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2899819
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88. Maheshwari AV, Muro-Cacho CA, Kransdorf MJ, Temple HT: Soft-tissue amyloidoma of the extremities: a case report and review of literature. Skeletal Radiol; 2009 Mar;38(3):287-92
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  • The least common presentation of an amyloid deposition is as a discrete mass called amyloidoma or amyloid tumor.
  • In spite of attaining a very large size over a course of more than 20 years, the clinical course and the histology of this lesion were benign.
  • Awareness of this entity will allow this rare diagnosis to be considered, prevent confusion with malignant disease, and allow appropriate management and patient reassurance.
  • [MeSH-major] Amyloidosis / diagnosis. Leg / pathology
  • [MeSH-minor] Aged, 80 and over. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 19050870.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 29
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89. Weber KL, Peabody T, Frassica FJ, Mott MP, Parsons TW 3rd: Tumors for the general orthopedist: how to save your patients and practice. Instr Course Lect; 2010;59:579-91
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  • It is likely that most orthopaedic surgeons will see a patient with a benign or malignant musculoskeletal tumor sometime during their career.
  • A logical approach is necessary in evaluating imaging studies as well as in the workup of children and adults with a possible tumor.
  • If the treatment algorithms lead to a conclusive diagnosis of a benign bone tumor, benign soft-tissue mass, or metastatic bone disease, the orthopaedic surgeon may choose to definitively treat the patient.
  • [MeSH-major] Bone Neoplasms / diagnosis. Bone Neoplasms / surgery. Cysts / diagnosis. Joint Diseases / pathology. Orthopedics. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 20415407.001).
  • [ISSN] 0065-6895
  • [Journal-full-title] Instructional course lectures
  • [ISO-abbreviation] Instr Course Lect
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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90. Vigler M, Levine LJ, Posner MA: Multiple neurilemomas in the upper extremity: a series of three cases. Bull NYU Hosp Jt Dis; 2008;66(1):61-4
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  • Neurilemomas are the most frequently arising benign nerve tumors of the upper extremity and are also called Schwannomas.
  • We present three patients who had multiple neurilemomas; two patients had tumors within a single major nerve and its branches, and the third patient had an unusual occurrence of one tumor in the ulnar nerve and a second tumor in a branch of the median nerve.

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  • (PMID = 18333831.001).
  • [ISSN] 1936-9719
  • [Journal-full-title] Bulletin of the NYU hospital for joint diseases
  • [ISO-abbreviation] Bull NYU Hosp Jt Dis
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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91. Bell WC, Klein MJ, Pitt MJ, Siegal GP: Molecular pathology of chondroid neoplasms: part 2, malignant lesions. Skeletal Radiol; 2006 Dec;35(12):887-94
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  • This is the second part of a two-part review presenting an overview of the molecular findings associated with both benign and malignant chondroid neoplasms.
  • The first part presented a brief review of modern methods in molecular pathology, along with a review of the cytogenetic and molecular genetic findings in benign chondroid neoplasms.
  • Clinical aspects of the various lesions are briefly discussed, and each tumor is illustrated with representative radiographic and pathologic images.

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  • (PMID = 17047898.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Grant] United States / NIAMS NIH HHS / AR / AR 046031; United States / NCI NIH HHS / CA / CA 098543; United States / NCI NIH HHS / CA / CA 93796
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Germany
  • [Number-of-references] 63
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92. Zhang Y, Forootan SS, Liu D, Barraclough R, Foster CS, Rudland PS, Ke Y: Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients. Prostate Cancer Prostatic Dis; 2007;10(3):293-300
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  • The relative levels of AGR2 expression in the malignant cell lines PC-3 and PC-3M were, respectively, 5.3+/-0.1 and 3.8+/-0.2 times that detected in the benign cell line PNT-2.
  • Amongst 34 benign prostate hyperplastic (BPH) cases, 12 (35.3%) were unstained, 18 (52.9%) stained weakly positive and four (11.8%) stained moderately positive.
  • Increased joint Gleason score (GS) was significantly (log rank test, P=0.001) associated with poor patient survival.
  • [MeSH-major] Adenocarcinoma / metabolism. Adenocarcinoma / mortality. Biomarkers, Tumor / analysis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / mortality. Proteins / metabolism
  • [MeSH-minor] Aged. Blotting, Western. Cell Line, Tumor. Gene Expression. Humans. Immunohistochemistry. Kaplan-Meier Estimate. Male. Neoplasm Staging. Prostate-Specific Antigen / blood


93. Toy PC, France J, Randall RL, Neel MD, Shorr RI, Heck RK: Reconstruction of noncontained distal femoral defects with polymethylmethacrylate and crossed-screw augmentation: a biomechanical study. J Bone Joint Surg Am; 2006 Jan;88(1):171-8
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  • BACKGROUND: Curettage and cementation with polymethylmethacrylate are frequently used in the treatment of aggressive benign bone lesions such as giant-cell tumors, but strength and stiffness of the reconstructed bone have been concerns.
  • CONCLUSIONS: In this in vitro cadaver study, augmentation of polymethylmethacrylate cement with crossed screws resulted in a stronger reconstruction of distal femoral tumor defects than that obtained with cement alone or with cement and intramedullary Steinmann pins.

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  • (PMID = 16391262.001).
  • [ISSN] 0021-9355
  • [Journal-full-title] The Journal of bone and joint surgery. American volume
  • [ISO-abbreviation] J Bone Joint Surg Am
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Cements; 9011-14-7 / Polymethyl Methacrylate
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94. Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW Jr: Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion. Cancer Lett; 2009 Sep 28;283(1):29-35
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  • In this study, we present the first evidence that CXCL13, the only ligand for CXCR5, and IL-6 were significantly elevated in PCa patient serum compared to serum from subjects with benign prostatic hyperplasia (BPH), or high-grade prostatic intraepithelial neoplasia (HGPIN) as well as normal healthy donors (NHD).

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  • (PMID = 19375853.001).
  • [ISSN] 1872-7980
  • [Journal-full-title] Cancer letters
  • [ISO-abbreviation] Cancer Lett.
  • [Language] ENG
  • [Grant] United States / NCRR NIH HHS / RR / G12 RR003034-27; United States / NCRR NIH HHS / RR / G12 RR003034-23; United States / NCRR NIH HHS / RR / G12 RR003034; United States / NCI NIH HHS / CA / U24 CA086359-10; United States / NIMHD NIH HHS / MD / P60 MD000525-03; United States / NIMHD NIH HHS / MD / MD00525; United States / NIMHD NIH HHS / MD / P60 MD000525; United States / NIAID NIH HHS / AI / AI057808; United States / NCRR NIH HHS / RR / RR003034-23; United States / NIGMS NIH HHS / GM / S06 GM008248; United States / NIGMS NIH HHS / GM / GM09248; United States / NCRR NIH HHS / RR / RR03034; United States / NIGMS NIH HHS / GM / GM008248-22; United States / NIAID NIH HHS / AI / R01 AI057808; United States / NIDDK NIH HHS / DK / DK58967; United States / NCI NIH HHS / CA / U24CA86359.; United States / NCI NIH HHS / CA / U24 CA086359; United States / NIGMS NIH HHS / GM / GM08248; United States / NIGMS NIH HHS / GM / S06 GM008248-22; United States / NCI NIH HHS / CA / U56 CA092078; United States / NCI NIH HHS / CA / CA086359-10; United States / NCI NIH HHS / CA / CA092078
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CXCL13 protein, human; 0 / CXCR5 protein, human; 0 / Chemokine CXCL13; 0 / Integrins; 0 / Interleukin-6; 0 / Receptors, CXCR5; EC 3.4.21.77 / Prostate-Specific Antigen
  • [Other-IDs] NLM/ NIHMS140687; NLM/ PMC3600557
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95. Ioannou M, Papanastassiou J, Athanassiou AE, Ziras N, Kottakis S, Demertzis N: Surgical options in cases of tumorous destruction of the proximal humerus: twenty-one patients followed from 4-9 years. J BUON; 2009 Jan-Mar;14(1):57-61
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  • PURPOSE: To compare the postoperative outcomes of several techniques of reconstructive surgery for malignant and aggressive benign tumors of the proximal humerus.
  • PATIENTS AND METHODS: Twenty-one shoulder reconstructions following tumor resection were studied.
  • Nine cases with an intracompartmental tumor were treated with endoprosthetic reconstruction.
  • Three cases with the tumor involving the glenoid were treated with a typical Malawer VB shoulder girdle resection.
  • In 4 patients with extracompartmental excision the authors proceeded to skeletal reconstruction using a modular endoprosthesis, while soft tissue reconstruction was undertaken using monofilament polypropylene mesh in order to enforce joint stability.
  • [MeSH-major] Arthroplasty, Replacement. Bone Neoplasms / surgery. Humerus / surgery. Joint Instability / surgery. Orthopedic Procedures. Shoulder Joint / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Female. Humans. Joint Prosthesis. Magnetic Resonance Imaging. Male. Middle Aged. Recovery of Function. Rotator Cuff / surgery. Surgical Mesh. Time Factors. Treatment Outcome. Young Adult

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  • (PMID = 19373948.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
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96. Srikantha U, Bhagavatula ID, Satyanarayana S, Somanna S, Chandramouli BA: Spinal osteochondroma: spectrum of a rare disease. J Neurosurg Spine; 2008 Jun;8(6):561-6
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  • Osteochondromas are the most common benign bone tumor.
  • The patient in Case 3 presented with monoradiculopathy and had a facet joint osteochondroma that was successfully treated with a simple partial facetectomy, without laminectomy.
  • [MeSH-major] Cervical Vertebrae / pathology. Osteochondroma / diagnosis. Spinal Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Adult. Constriction, Pathologic / diagnosis. Diagnosis, Differential. Female. Humans. Male. Peripheral Vascular Diseases / diagnosis. Spinal Cord Compression / diagnosis. Vertebral Artery / pathology

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  • (PMID = 18518678.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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97. Panasiuk M, Iwański A: Diagnostic difficulties in pigmented villonodular synovitis. Presentation of cases. Ortop Traumatol Rehabil; 2008 Nov-Dec;10(6):613-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the literature, this condition has been called xanthoma, xanthogranuloma, villous arthritis, pigmented villonodular synovitis, xanthomatous giant cell tumour, giant cell tumour of tendon sheath, giant cell fibrohemangioma, benign synovioma.
  • [MeSH-major] Synovitis, Pigmented Villonodular / diagnosis. Synovitis, Pigmented Villonodular / surgery
  • [MeSH-minor] Adolescent. Ankle Joint. Diagnosis, Differential. Female. Giant Cell Tumor of Bone / diagnosis. Hemangioma / diagnosis. Humans. Knee Joint / blood supply. Magnetic Resonance Imaging. Middle Aged. Synovial Membrane / surgery. Terminology as Topic

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  • (PMID = 19153550.001).
  • [ISSN] 1509-3492
  • [Journal-full-title] Ortopedia, traumatologia, rehabilitacja
  • [ISO-abbreviation] Ortop Traumatol Rehabil
  • [Language] eng; pol
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
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98. Hornick JL, Fletcher CD: Intraarticular nodular fasciitis--a rare lesion: clinicopathologic analysis of a series. Am J Surg Pathol; 2006 Feb;30(2):237-41
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nodular fasciitis is a benign myofibroblastic proliferation with a predilection for the subcutaneous tissues of the upper extremities, trunk, and head and neck of young adults.
  • Most patients complained of joint pain; 4 presented with a palpable mass.
  • The clinical differential diagnoses included giant cell tumor of tendon sheath, pigmented villonodular synovitis, synovial chondromatosis, inflammatory arthritis, and lymphoma.
  • [MeSH-major] Fasciitis / metabolism. Fasciitis / pathology. Joint Diseases / metabolism. Joint Diseases / pathology
  • [MeSH-minor] Adolescent. Adult. Child. Diagnosis, Differential. Female. Fibroma / pathology. Humans. Immunohistochemistry. Knee Joint / pathology. Male. Middle Aged. Myxoma / pathology. Tendons / pathology

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  • (PMID = 16434899.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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99. Lara-Barragán EH, Zamudio-Carrera E, Martínez-Molina OA: [Chondroblastoma of the proximal humerus treated with intracompartmental curettage and lyophilized bone graft. Case report and literature review]. Acta Ortop Mex; 2008 Sep-Oct;22(5):335-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondroblastoma is a chondroid bone tumor that frequently affects long bone epiphysis, malignancy occurs infrequently.
  • It can alter the morphology of the joint, and appears in the second decade of life before ossification of the physes.
  • According to Enneking's classification, chondroblastoma is benign injury, with capacity of physes destruction.

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  • (PMID = 19227941.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Mexico
  • [Number-of-references] 20
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100. Donati D, Colangeli M, Colangeli S, Di Bella C, Mercuri M: Allograft-prosthetic composite in the proximal tibia after bone tumor resection. Clin Orthop Relat Res; 2008 Feb;466(2):459-65
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  • [Title] Allograft-prosthetic composite in the proximal tibia after bone tumor resection.
  • By combining an allograft with a prosthesis, placing cement in the graft, and press-fitting the prosthesis in the tibial diaphysis, we obtained satisfactory Musculoskeletal Tumor Society scores in 90.4% of patients, with a 5-year survival rate (73.4%) comparable to that of reconstruction with a modular prosthesis.
  • We believe the ideal candidate is the young patient with a benign aggressive or malignant low-grade tumor who has not undergone previous surgery.

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  • (PMID = 18196432.001).
  • [ISSN] 0009-921X
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2505118
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