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1. Hoshimoto S, Morise Z, Takeura C, Ikeda M, Kagawa T, Tanahashi Y, Okabe Y, Mizoguchi Y, Sugioka A: Malignant Triton tumor in the retroperitoneal space associated with neurofibromatosis type 1: a case study. Rare Tumors; 2009;1(2):e27
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  • [Title] Malignant Triton tumor in the retroperitoneal space associated with neurofibromatosis type 1: a case study.
  • We report an extremely rare case of malignant Triton tumor developing in the retroperitoneal space in a patient with neurofibromatosis type 1.
  • Abdominal computed tomography revealed a huge heterogeneous tumor measuring approximately 17 cm in diameter occupying the left retroperitoneal space, and numerous metastatic lesions between the left psoas muscle and the left thigh with dissolution of the left hip joint.
  • After the diagnosis of a retroperitoneal malignant neurogenic tumor, resection of the tumor with reconstruction of the abdominal aorta was conducted, followed by postoperative transarterial infusion chemotherapy.
  • The histopathological diagnosis was malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation, namely malignant Triton tumor.

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  • (PMID = 21139906.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994481
  • [Keywords] NOTNLM ; malignant Triton tumor / malignant peripheral nerve sheath tumor / neurofibromatosis / retroperitoneal tumor.
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2. Terzic A, Bode B, Gratz KW, Stoeckli SJ: Prognostic factors for the malignant triton tumor of the head and neck. Head Neck; 2009 May;31(5):679-88
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  • [Title] Prognostic factors for the malignant triton tumor of the head and neck.
  • BACKGROUND: Malignant triton tumors are rare neoplasias consisting of a malignant peripheral nerve sheath tumor with additional rhabdomyoblastic differentiation.
  • These tumors are highly aggressive and prognosis is poor.
  • METHODS: From 1993 to 2005, 7 patients with a malignant triton tumor of the head and neck were treated at our institution.
  • RESULTS: Patients with primary tumors involving the nose and paranasal sinuses have better, patients involving the neck a poor prognosis.
  • CONCLUSION: Location of the primary tumor is a key factor for prognosis.

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  • (PMID = 19283843.001).
  • [ISSN] 1097-0347
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 47
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3. Bura M, Musani V, Cretnik M, Botica I, Levanat S: Hedgehog-Patched pathway aberrations in a malignant triton tumor case study. Oncol Rep; 2008 Aug;20(2):347-52
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  • [Title] Hedgehog-Patched pathway aberrations in a malignant triton tumor case study.
  • Transition from malignant schwannoma to malignant triton tumor is analyzed in a case report on a patient with recurring cancers and suspected familial predisposition.
  • It is hypothesized that rhabdomyoblastic differentiation, which distinguishes triton from schwannoma, might be attributable to Hedgehog-Patched pathway malfunctioning.
  • Loss of one Patched gene allele was found in the tissue of advanced triton, but the retained allele had no exon or promoter mutations.
  • Protein levels at early cancer stages indicated possible Patched response to the pathway activation in the first occurrence of triton tumor.
  • Later, in the recurring triton, Patched expression was several times lower than in the control tissue, suggesting that haploinsufficiency was aided by silencing of the remaining allele, although its promoter was not hypermethylated.
  • These findings may justify further investigation of the Hedgehog-Patched pathway role in triton malignancies, especially because of the recent research on the therapeutical potential of the pathway.

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  • (PMID = 18636196.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / GLI1 protein, human; 0 / Hedgehog Proteins; 0 / Neoplasm Proteins; 0 / Neurofibromin 1; 0 / P16 protein, human; 0 / Receptors, Cell Surface; 0 / Receptors, G-Protein-Coupled; 0 / SHH protein, human; 0 / SMO protein, human; 0 / Transcription Factors; 0 / patched receptors
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4. Daley TD, Darling MR, Wehrli B: Benign Triton tumor of the tongue. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Jun;105(6):763-6
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  • [Title] Benign Triton tumor of the tongue.
  • A case of the extremely rare benign Triton tumor of the tongue is presented.

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  • (PMID = 18299216.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Desmin; 0 / S100 Proteins
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5. Sönmez K, Türkyilmaz Z, Karabulut R, Kapisiz A, Eser EP, Memiş L, Başaklar AC: A Triton tumor mimicking sacrococcygeal teratoma. J Pediatr Surg; 2009 Nov;44(11):e5-8
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  • [Title] A Triton tumor mimicking sacrococcygeal teratoma.
  • On the 16th day of age, the tumor was completely removed.
  • Histopathologic examination of the tumor showed malignant Triton tumor (MTT).

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  • (PMID = 19944207.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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6. Ferrari A, Bisogno G, Macaluso A, Casanova M, D'Angelo P, Pierani P, Zanetti I, Alaggio R, Cecchetto G, Carli M: Soft-tissue sarcomas in children and adolescents with neurofibromatosis type 1. Cancer; 2007 Apr 1;109(7):1406-12
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: The study included 37 patients with neurogenic sarcomas (36 malignant peripheral nerve sheath tumors [MPNST], 1 triton tumor) and 6 cases of rhabdomyosarcoma (RMS).
  • RESULTS: Most patients with neurogenic sarcomas had large, invasive tumors.


7. Vallejo Vaz AJ, Grijalvo OM, Parra MC, García EM: [Fistulating bowel disease and abscess due to neuromuscular hamartoma of ileum and cecum]. Med Clin (Barc); 2009 Jan 31;132(3):120-1
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  • [Title] [Fistulating bowel disease and abscess due to neuromuscular hamartoma of ileum and cecum].
  • [Transliterated title] Enfermedad intestinal fistulizante y absceso por hamartoma neuromuscular de íleon y ciego.
  • [MeSH-major] Abdominal Abscess / etiology. Cecal Diseases / complications. Hamartoma / complications. Ileal Diseases / complications. Intestinal Fistula / etiology

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  • (PMID = 19211068.001).
  • [ISSN] 0025-7753
  • [Journal-full-title] Medicina clínica
  • [ISO-abbreviation] Med Clin (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Spain
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8. Rekhi B, Jambhekar NA, Puri A, Agrawal M, Chinoy RF: Clinicomorphologic features of a series of 10 cases of malignant triton tumors diagnosed over 10 years at a tertiary cancer hospital in Mumbai, India. Ann Diagn Pathol; 2008 Apr;12(2):90-7
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  • [Title] Clinicomorphologic features of a series of 10 cases of malignant triton tumors diagnosed over 10 years at a tertiary cancer hospital in Mumbai, India.
  • A rhabdomyoblastic differentiation in a malignant peripheral nerve sheath tumor is unusual and is termed as a malignant triton tumor.
  • Distinct rhabdomyoblastic cells were identified in the areas of malignant peripheral nerve sheath tumor.
  • Malignant triton tumor is an uncommon tumor associated with an aggressive behavior.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / metabolism. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Recurrence, Local. S100 Proteins / analysis. Treatment Outcome

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  • (PMID = 18325468.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins
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9. Cano JR, Algar FJ, Alvarez A, Salvatierra A: Triton tumor of the left sympathetic nerve. Interact Cardiovasc Thorac Surg; 2006 Dec;5(6):790-1
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  • [Title] Triton tumor of the left sympathetic nerve.
  • Malignant triton tumor is a subtype of malignant peripheral nerve sheath tumor which presents a rabdomyoblastic differentiation.
  • We report the case of a 14-year-old male with a radical surgical resection of a mediastinal malignant triton tumor of the sympathetic nerve, a rare location for this tumor.
  • The prognosis for this group of tumors is poor.
  • Radical surgical excision of the tumor followed by radiation therapy must be the treatment of choice.

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  • (PMID = 17670715.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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10. Kim DH, Murovic JA, Tiel RL, Moes G, Kline DG: A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center. J Neurosurg; 2005 Feb;102(2):256-66
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  • [Title] A series of 146 peripheral non-neural sheath nerve tumors: 30-year experience at Louisiana State University Health Sciences Center.
  • OBJECT: This is a retrospective review of 146 surgically treated benign and malignant peripheral non-neural sheath tumors (PNNSTs).
  • Tumor classifications with patient numbers, locations of benign PNNSTs, and surgical techniques and adjunctive treatments are presented.
  • The results of a literature review regarding tumor frequencies are presented.
  • METHODS: One hundred forty-six patients with 111 benign and 35 malignant PNNSTs were treated between 1969 and 1999 at the Louisiana State University Health Sciences Center (LSUHSC).
  • The benign tumors included 33 ganglion cysts, 16 cases of localized hypertrophic neuropathy, 12 lipomas, 12 tumors of vascular origin, and 11 desmoid tumors.
  • There were four each of lipofibrohamartomas, myositis ossificans, osteochondromas, and ganglioneuromas; two each of meningiomas, cystic hygromas, myoblastoma or granular cell tumors, triton tumors, and lymphangiomas; and one epidermoid cyst.
  • The locations of benign PNNSTs were the following: 33 in the brachial plexus region, 39 in an upper extremity, one in the pelvic plexus, and 38 in a lower extremity.
  • There were two melanomas metastatic to nerve and one tumor each that had metastasized from the bladder, rectum, skin, head and neck, and thyroid, and from a primary Ewing sarcoma.
  • CONCLUSIONS: There were more benign PNNSTs than malignant ones.
  • Benign tumors were relatively equally distributed in the brachial plexus region and upper and lower extremities, with the exception of the pelvic plexus, which had only one tumor.

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  • (PMID = 15739553.001).
  • [ISSN] 0022-3085
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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11. Company MM, Usamentiaga E, Torralba J, Bonet L: [Small bowel diaphragm disease associated with NSAIDs with histology of neuromuscular and vascular hamartoma. Case report and literature review]. Gastroenterol Hepatol; 2005 Apr;28(4):228-31
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  • [Title] [Small bowel diaphragm disease associated with NSAIDs with histology of neuromuscular and vascular hamartoma. Case report and literature review].
  • [Transliterated title] Enfermedad diafragmática intestinal asociada a AINE con histología de hamartoma neuromuscular y vascular. Presentación de un caso y revisión de la bibliografía.
  • Diaphragm disease (DD) induced by non-steroidal anti-inflammatory drugs (NSAIDs) and neuromuscular and vascular hamartoma (NMVH) are rare entities that can be difficult to recognize clinically, radiologically and pathologically.
  • [MeSH-major] Anti-Inflammatory Agents, Non-Steroidal / adverse effects. Hamartoma / chemically induced. Ileal Diseases / chemically induced. Intestinal Obstruction / etiology

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  • (PMID = 15811265.001).
  • [ISSN] 0210-5705
  • [Journal-full-title] Gastroenterología y hepatología
  • [ISO-abbreviation] Gastroenterol Hepatol
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal
  • [Number-of-references] 14
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13. Stasik CJ, Tawfik O: Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor). Arch Pathol Lab Med; 2006 Dec;130(12):1878-81
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  • [Title] Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation (malignant triton tumor).
  • Malignant peripheral nerve sheath tumors arise from Schwann cells or within existing neurofibromas and have a strong association with type 1 neurofibromatosis.
  • These tumors are histologically diverse and may contain malignant areas of divergent mesenchymal differentiation, the most common of which is skeletal muscle (rhabdomyosarcoma).
  • Malignant peripheral nerve sheath tumor with rhabdomyosarcomatous differentiation is also known as malignant triton tumor.
  • Malignant triton tumor has a worse prognosis than classic malignant peripheral nerve sheath tumor does, and the correct diagnosis requires attention to the clinical history and knowledge of the complexities regarding its differential diagnosis.
  • [MeSH-minor] Antigens, CD57 / analysis. Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Myelin Basic Protein / analysis. S100 Proteins / analysis

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  • (PMID = 17149968.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD57; 0 / Biomarkers, Tumor; 0 / Myelin Basic Protein; 0 / S100 Proteins
  • [Number-of-references] 19
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14. Uysal A, Sungur N, Koçer U, Cöloğlu H, Oruç M, Yalta T: Neuromuscular hamartoma of the occipital nerve: clinical report. J Craniofac Surg; 2005 Jul;16(4):740-2
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  • [Title] Neuromuscular hamartoma of the occipital nerve: clinical report.
  • Neuromuscular hamartoma is a rare benign tumor consisted of well-differentiated striated muscle fibers within mature neural elements.
  • Though most cases are composed of solitary masses associated with major peripheral nerves, multiple tumors or subcutaneous tumors without any association with peripheral nerves have also been reported.
  • Twenty-three neuromuscular hamartomas of various anatomical locations have been reported in English literature.
  • There have been no reports of this tumor in association with the occipital nerve.
  • An interesting case of neuromuscular hamartoma of the occipital nerve is presented and previous reports about this rare pathology is reviewed.
  • [MeSH-major] Hamartoma / pathology. Spinal Nerves
  • [MeSH-minor] Child. Female. Humans. Muscle Fibers, Skeletal. Nerve Fibers. Neuromuscular Diseases / pathology. Neuromuscular Diseases / surgery. Occipital Bone. Scalp / innervation

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  • (PMID = 16077331.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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15. Schrecengost JE, Tabbara S, Patterson J, Wick MR: Cutaneous mesenchymal hamartoma with mixed myogenous differentiation. J Cutan Pathol; 2006 Apr;33(4):327-30
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  • [Title] Cutaneous mesenchymal hamartoma with mixed myogenous differentiation.
  • They must be distinguished from a variety of other tumors, including juvenile rhabdomyoma, benign Triton tumor, and rhabdomyosarcoma.
  • [MeSH-major] Cell Differentiation. Dermis / pathology. Hamartoma / diagnosis. Mesoderm / pathology. Skin Neoplasms / diagnosis

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  • (PMID = 16630187.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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16. Busam KJ, Kucukgöl D, Sato E, Frosina D, Teruya-Feldstein J, Jungbluth AA: Immunohistochemical analysis of novel monoclonal antibody PNL2 and comparison with other melanocyte differentiation markers. Am J Surg Pathol; 2005 Mar;29(3):400-6
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  • PNL2 is a novel monoclonal antibody, which has recently been introduced as an immunohistochemical reagent to stain melanocyte and tumors derived thereof.
  • In the present study, we analyzed the immunoreactivity of this mAb in various normal tissues, melanocytic nevi, primary and metastatic melanoma, nonmelanocytic tumors, including histologic mimickers of melanoma as well as angiomyolipoma, and multiple cell lines derived from different tumors types.
  • Among melanocytic lesions, both benign nevi as well as primary malignant melanomas, especially epithelioid variants thereof, were commonly immunopositive.
  • None of the selected nonmelanocytic tumors (carcinomas or soft tissue neoplasms) was positive for PNL2 in this series except for angiomyolipomas and chronic myeloid leukemias and 1 single case of a malignant peripheral nerve sheath tumor with heterologous differentiation (malignant Triton tumor).
  • Despite its reactivity with neutrophils, PNL2 appears to be a valuable supplementary reagent for the diagnosis of melanocytic tumors.

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  • (PMID = 15725810.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Biomarkers
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17. Tobias S, Kim CH, Sade B, Staugaitis SM, Lee JH: Neuromuscular hamartoma of the trigeminal nerve in an adult. Acta Neurochir (Wien); 2006 Jan;148(1):83-7; discussion 87
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  • [Title] Neuromuscular hamartoma of the trigeminal nerve in an adult.
  • Frozen section was suggestive of a neuromuscular hamartoma.
  • Neuromuscular hamartoma should be included in the differential diagnosis of cavernous sinus and cranial nerve lesions in adults.
  • [MeSH-major] Hamartoma / diagnosis. Hamartoma / surgery. Trigeminal Nerve Diseases / diagnosis. Trigeminal Nerve Diseases / surgery

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  • (PMID = 16228126.001).
  • [ISSN] 0001-6268
  • [Journal-full-title] Acta neurochirurgica
  • [ISO-abbreviation] Acta Neurochir (Wien)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Austria
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18. Yamamoto Y, Ibusuki M, Okumura Y, Kawasoe T, Kai K, Iyama K, Iwase H: Hypoxia-inducible factor 1alpha is closely linked to an aggressive phenotype in breast cancer. Breast Cancer Res Treat; 2008 Aug;110(3):465-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • EXPERIMENTAL DESIGN: We examined, by immunohistochemical analysis, the expression of HIF-1alpha in normal breast tissue, benign disorders and breast cancer.
  • RESULTS: HIF-1alpha was mainly detected in tumor cell nuclei.
  • Immunoreactive nuclear HIF-1alpha was correlated with tumor size (p = 0.0013), lymph node metastasis (p = 0.0005), tumor stage (p = 0.0031) and histological grade (p = 0.0074).
  • In terms of the possible use of HIF-1alpha as a prognostic indicator, patients who had increased HIF-1alpha levels in their tumor showed shorter disease-free survival (DFS) (p < 0.0001) and overall survival (OS) (p = 0.0002) than those lacking HIF-1alpha in univariate analysis.
  • It may be useful to study the expression of HIF-1alpha using immunohistochemical analysis for better understanding of the tumor characteristics of breast cancer.
  • [MeSH-major] Biomarkers, Tumor / analysis. Breast Diseases / pathology. Breast Neoplasms / pathology. Carcinoma, Ductal, Breast / pathology. Hypoxia-Inducible Factor 1, alpha Subunit / biosynthesis


19. Zisis C, Fragoulis S, Rontogianni D, Stratakos G, Bellenis I: Malignant triton tumour of the anterior mediastinum as incidental finding. Monaldi Arch Chest Dis; 2006 Dec;65(4):222-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant triton tumour of the anterior mediastinum as incidental finding.
  • A rare case of malignant peripheral nerve sheath tumour with rhabdomyoblastic differentiation (malignant triton tumour) of the anterior mediastinum in a 30-year-old male is reported.
  • The tumour was an incidental finding during the diagnostic work-up following a motor vehicle accident.
  • The patient underwent median sternotomy with a tumour resection performed.
  • Localization of a triton tumour in the anterior mediastinum is extremely rare, adjuvant treatment is necessary, recurrence frequently occurs and the prognosis is dismal.

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  • (PMID = 17393668.001).
  • [ISSN] 1122-0643
  • [Journal-full-title] Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
  • [ISO-abbreviation] Monaldi Arch Chest Dis
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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20. James G, Crocker M, King A, Bodi I, Ibrahim A, Chitnavis BP: Malignant triton tumors of the spine. J Neurosurg Spine; 2008 Jun;8(6):567-73
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant triton tumors of the spine.
  • Malignant triton tumors (MTTs) are malignant peripheral nerve sheath tumors with rhabdomyosarcomatous differentiation.
  • Malignant triton tumors affecting the spine are rare but present special challenges to the neurosurgeon.
  • Seven patients had intradural extension of tumor.
  • Malignant triton tumors are rare but should be included in the differential diagnosis of spinal tumors, particularly in patients who have undergone previous radiotherapy or who have neurofibromatosis.

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  • (PMID = 18518679.001).
  • [ISSN] 1547-5654
  • [Journal-full-title] Journal of neurosurgery. Spine
  • [ISO-abbreviation] J Neurosurg Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Desmin; 0 / Ki-67 Antigen; 0 / S100 Proteins; 0 / Vimentin
  • [Number-of-references] 13
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21. Castro DE, Raghuram K, Phillips CD: Benign triton tumor of the trigeminal nerve. AJNR Am J Neuroradiol; 2005 Apr;26(4):967-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign triton tumor of the trigeminal nerve.
  • Benign triton tumors (neuromuscular hamartomas) are rare neoplasms composed of well-differentiated striated muscle fibers admixed with peripheral nerve fibers.
  • To the best of our knowledge, this is the third case reported in the world literature of a benign triton tumor involving cranial nerve V (trigeminal nerve) and the first in the radiology literature.
  • [MeSH-major] Hamartoma / diagnosis. Trigeminal Nerve Diseases / diagnosis

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  • (PMID = 15814954.001).
  • [ISSN] 0195-6108
  • [Journal-full-title] AJNR. American journal of neuroradiology
  • [ISO-abbreviation] AJNR Am J Neuroradiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 10
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22. Bien E, Stachowicz-Stencel T, Sierota D, Polczynska K, Szolkiewicz A, Stefanowicz J, Adamkiewicz-Drozynska E, Czauderna P, Kosiak W, Dubaniewicz-Wybieralska M, Izycka-Swieszewska E, Balcerska A: Sarcomas in children with neurofibromatosis type 1-poor prognosis despite aggressive combined therapy in four patients treated in a single oncological institution. Childs Nerv Syst; 2007 Oct;23(10):1147-53
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Patients with malignant peripheral nerve sheet tumour and malignant triton tumour located in the pelvis did not respond to therapy.
  • One of them died of disease progression, while the other is disease-free 6 years post-therapy after mutilating tumour resection.

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  • (PMID = 17628808.001).
  • [ISSN] 0256-7040
  • [Journal-full-title] Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • [ISO-abbreviation] Childs Nerv Syst
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents
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23. Kabir S, Kapetanakis EI, Shabbo F: Intracardiac malignant Triton tumor: a first presentation. Ann Thorac Surg; 2010 Mar;89(3):968-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intracardiac malignant Triton tumor: a first presentation.
  • We present the first case of an intracardiac malignant peripheral nerve sheath tumor with rhabdomyoblastic differentiation (malignant Triton tumor) in a 63-year-old man who underwent elective, uncomplicated resection of his symptomatic left atrial mass.

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20172170.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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24. Cunniffe G, Fernández J, Alonso T, Balaguer O, Dinares C, Huguet P, Medel R: Thyroid orbitopathy obscuring the diagnosis of a rare neuromuscular hamartoma of the superior rectus muscle in an adult. Orbit; 2010 Jun;29(3):168-70
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Thyroid orbitopathy obscuring the diagnosis of a rare neuromuscular hamartoma of the superior rectus muscle in an adult.
  • A neuromuscular hamartoma is a rare benign tumour that is most frequently associated with peripheral nerves.
  • This showed the presence of a neuromuscular hamartoma without malignant features.
  • A neuromuscular hamartoma not associated with a peripheral nerve is a rare entity, especially when coupled with an extraocular muscle.
  • [MeSH-major] Graves Ophthalmopathy / diagnosis. Hamartoma / diagnosis. Neuromuscular Diseases / diagnosis. Oculomotor Muscles / pathology. Orbital Diseases / diagnosis

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  • (PMID = 20497087.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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25. Kawamoto S, Matsuda H, Ueki K, Okada Y, Kim P: Neuromuscular choristoma of the oculomotor nerve: case report. Neurosurgery; 2007 Apr;60(4):E777-8; discussion E778
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Neuromuscular choristoma of the oculomotor nerve: case report.
  • OBJECTIVE: Neuromuscular choristomas (NMC) are rare benign tumors of the peripheral nerves.
  • INTERVENTION: The tumor was resected with the parental oculomotor nerve, which was reconstructed using a peroneal nerve graft.

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  • (PMID = 17415185.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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26. Polish Paediatric Solid Tumours Study Group, Bień E, Stachowicz-Stencel T, Kazanowska B, Balcerska A, Balwierz W, Chybicka A, Dłuzniewska A, Drozyńska E, Kurylak A, Matysiaks M, Krawczuk-Rybak M, Rychłowska M, Solarz E, Sopyło B, Stencels D, Wachowiaks J, Wieczorek M, Woźniak W, Wysocki M: [Genitourinary soft tissue sarcomas located outside bladder and prostate in children treated according to the CWS-96 protocol--report from the Polish Paediatric Solid Tumours Study Group]. Med Wieku Rozwoj; 2005 Jul-Sep;9(3 Pt 2):507-15
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Genitourinary soft tissue sarcomas located outside bladder and prostate in children treated according to the CWS-96 protocol--report from the Polish Paediatric Solid Tumours Study Group].
  • Primary tumour exceeded 5cm and/or invaded surrounding tissues in 7 patients (37%).
  • Six of 7 patients with macroscopic tumour residues responded to chemotherapy (CR-4, GR-2).
  • One patient (stage III triton tumour of uterus) did not, respond but obtained complete remission after mutilating delayed surgery.
  • No other patient required delayed tumour resection.

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  • (PMID = 16719163.001).
  • [Journal-full-title] Medycyna wieku rozwojowego
  • [ISO-abbreviation] Med Wieku Rozwoj
  • [Language] pol
  • [Publication-type] Clinical Trial; English Abstract; Journal Article
  • [Publication-country] Poland
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27. Radovanovic D, Vukotic-Maletic V, Stojanovic D, Lalosevic Dj, Likic I, Stojsic Z, Bacetic D: Retroperitoneal "Triton" tumor. Hepatogastroenterology; 2008 Mar-Apr;55(82-83):527-30
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Retroperitoneal "Triton" tumor.
  • Malignant Triton tumor is a malignant peripheral nerve sheat tumor with rhabdomioblastic differentiation.
  • These tumors are frequently associated with Neurofibromatosis type 1, sporadic cases being exteremly rare.
  • We present a 60-year-old female patient in whom a retroperitoneal presacral mass was postoperatively diagnosed as Triton tumor.
  • This case demonstrates the bad prognosis of malignant retroperitoneal tumors.

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  • (PMID = 18613401.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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28. Tringali S, Philippe C, Benchemam Y, Dumollard JM, Seguin P: [Malignant triton tumor of the sinonasal tract]. Rev Stomatol Chir Maxillofac; 2005 Apr;106(2):99-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Malignant triton tumor of the sinonasal tract].
  • [Transliterated title] Tumeur triton ethmoido-nasale.
  • INTRODUCTION: The combination of a malignant peripheral nerve sheath tumor with rhabdomyosarcomatous elements has been termed Malignant Triton Tumor (MTT).
  • This tumor was first reported in 1932 and the prognosis was poor.
  • The CT-scan revealed a tumor occupying the right ethmoid the right maxillary sinus and the homolateral nasal fossa.
  • Eight months later, the tumor relapsed with cerebral involvement.
  • Despite new surgery with two teams, a neurosurgical and a radiotherapy team, the tumor relapsed at the ethmoid-nasal level.

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  • (PMID = 15924096.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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29. Ballas K, Kontoulis TM, Papavasiliou A, Pissas D, Pavlidis T, Katsiki E, Venizelos I, Sakadamis A: A rare case of malignant triton tumor with pluridirectional differentiation. South Med J; 2009 Apr;102(4):435-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A rare case of malignant triton tumor with pluridirectional differentiation.
  • Based on immunohistochemistry, a malignant triton tumor, an uncommon subtype of peripheral nerve sheath tumor with rhabdomyosarcomatous elements, was diagnosed.
  • This pathologic finding is rare and seen in only a few cases of all malignant triton tumors.
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Chondrosarcoma / pathology. Diagnosis, Differential. Humans. Immunohistochemistry. Male. Osteosarcoma / pathology

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  • (PMID = 19279515.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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30. De Cauwer H, Bogers JP, Duwel V, den Hauwe V, Croese P, Van Marck E: An intracerebral intraparenchymatous triton tumor in a man with neurofibromatosis. J Neurol; 2007 Aug;254(8):1009-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An intracerebral intraparenchymatous triton tumor in a man with neurofibromatosis.
  • We report the second case of a cerebral intraparenchymatous malignant nerve sheath tumor, triton tumor variant.
  • The therapy of these aggressive tumors is rather disappointing as recurrence of the tumor despite complete surgical resection and even adjuvant radiotherapy and/or chemotherapy is seen in most patients.
  • It is still unknown if survival is influenced by tumor localization, size or malignancy grade.

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