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Items 1 to 100 of about 6284
1. Güneri EA, Akoğlu E, Sütay S, Ceryan K, Sağol O, Pabuçcuoğlu U: Plexiform neurofibroma of the tongue: a case report of a child. Turk J Pediatr; 2006 Apr-Jun;48(2):155-8
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  • [Title] Plexiform neurofibroma of the tongue: a case report of a child.
  • Despite their occurrence in the head and neck region, neural sheath tumors are rarely encountered in the oral cavity.
  • Generally, surgical resection represents the treatment of choice and the diagnosis can only be confirmed after histological examination.
  • [MeSH-major] Neurofibroma, Plexiform / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Cafe-au-Lait Spots / etiology. Child, Preschool. Diagnosis, Differential. Female. Humans. Neurilemmoma / pathology. Neurofibromatosis 1 / pathology

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  • (PMID = 16848118.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Turkey
  • [Number-of-references] 30
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2. Kumar M, Bahl A, Sharma DN, Sharma R, Gupta R, Ahmed S, Julka PK, Rath GK: Cylindric cell carcinoma of the base of the tongue: a rare variant of squamous cell carcinoma. J Cancer Res Ther; 2009 Apr-Jun;5(2):124-6
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  • [Title] Cylindric cell carcinoma of the base of the tongue: a rare variant of squamous cell carcinoma.
  • Only passing references have been made for its presentation in oropharynx including tonsils and the base of the tongue.
  • We report here a rare case of transitional cell carcinoma presenting in the base of the tongue.
  • We report here a case of cylindric cell carcinoma presenting in the base of the tongue.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Tongue Neoplasms / diagnosis

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  • (PMID = 19542670.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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3. Bomfin LE, Alves Fde A, de Almeida OP, Kowalski LP, Perez DE: Multiple granular cell tumors of the tongue and parotid gland. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2009 May;107(5):e10-3
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  • [Title] Multiple granular cell tumors of the tongue and parotid gland.
  • Parotid granular cell tumor (GCT) is a very rare tumor, with only 11 previously reported cases in the English-language literature.
  • This report describes an uncommon case of multiple GCT involving the tongue and parotid gland and provides a review of the literature.
  • In addition, during the oral exam a submucosal painless nodule was detected sited in the tongue apex.
  • Right superficial parotidectomy with conservation of the facial nerve and excision of the tongue nodule were performed.
  • Histologically, both oral and parotid lesions were composed of cells with large eosinophilic and granular cytoplasm, which presented strong positivity for S-100 protein and negativity for cytokeratin, confirming the diagnosis of multicentric GCT.
  • Multiple GCT involving tongue and parotid are very rare and are successfully treated by surgical excision.
  • [MeSH-major] Granular Cell Tumor / pathology. Neoplasms, Multiple Primary / pathology. Parotid Neoplasms / pathology. Tongue Neoplasms / pathology

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  • (PMID = 19426900.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / S100 Proteins
  • [Number-of-references] 17
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4. Wang J, Huo X, Ghovanloo M: A quadratic particle swarm optimization method for magnetic tracking of tongue motion in speech disorders. Conf Proc IEEE Eng Med Biol Soc; 2008;2008:4222-5
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  • [Title] A quadratic particle swarm optimization method for magnetic tracking of tongue motion in speech disorders.
  • We have devised a new magnetic localization technique to accurately track 3-D tongue movements during speech and ingestion.
  • A small permanent magnet secured on the tongue by tissue adhesives, is utilized as a tracer.
  • The magnetic field variations due to tongue motion are detected by three 3-axis magneto-inductive sensor modules outside the mouth, and wirelessly transmitted to a computer for further processing.
  • [MeSH-major] Electronics / instrumentation. Telemetry / instrumentation. Tongue / physiopathology. User-Computer Interface

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  • (PMID = 19163644.001).
  • [ISSN] 1557-170X
  • [Journal-full-title] Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference
  • [ISO-abbreviation] Conf Proc IEEE Eng Med Biol Soc
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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5. Vitsky A, Waire J, Pawliuk R, Bond A, Matthews D, Lacasse E, Hawes ML, Nelson C, Richards S, Piepenhagen PA, Garman RD, Andrews L, Thurberg BL, Lonning S, Ledbetter S, Ruzek MC: Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues. Am J Pathol; 2009 Jun;174(6):2137-49
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  • Histopathology revealed a unique, nonneoplastic cystic epithelial hyperplasia and tongue inflammation, as well as dental dysplasia and epithelial hyperplasia and inflammation of both the gingiva and esophagus.
  • By immunostaining, we found higher expression levels of active TGF-beta1 and TGF-beta3 in normal tongue and esophageal submucosa compared with gut mucosal tissues, as well as detectable TGF-beta1 in normal saliva by Western blot analysis.
  • Interestingly, mast cells within the tongue, esophagus, and skin co-localized predominantly with the TGF-beta1 expressed in these tissues.

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  • (PMID = 19406991.001).
  • [ISSN] 1525-2191
  • [Journal-full-title] The American journal of pathology
  • [ISO-abbreviation] Am. J. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Transforming Growth Factor beta
  • [Other-IDs] NLM/ PMC2684179
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6. Berg T: A structural account of phonological paraphasias. Brain Lang; 2006 Mar;96(3):331-56
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  • The notion of structure holds the key to an understanding of the differences among the following three types of data: slips of the tongue, slips of the pen (defined as errors committed by healthy, competent adults), and paraphasias.
  • A comparison of these three data types reveals that slips of the pen and paraphasias display striking similarities whereas slips of the tongue stand apart.
  • Hence, slips of the tongue are highly sensitive to structural effects.

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  • [RepublishedFrom] Brain Lang. 2005 Jul;94(1):104-29 [15896388.001]
  • (PMID = 16615177.001).
  • [ISSN] 0093-934X
  • [Journal-full-title] Brain and language
  • [ISO-abbreviation] Brain Lang
  • [Language] eng
  • [Publication-type] Corrected and Republished Article; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 131
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7. Marin S, Pouplier M, Harrington J: Acoustic consequences of articulatory variability during productions of /t/ and /k/ and its implications for speech error research. J Acoust Soc Am; 2010 Jan;127(1):445-61
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  • The most frequent error observed in the articulatory data is the production of /k/ and /t/ with simultaneous tongue tip and tongue dorsum constrictions.
  • Spectral analysis of these stimuli's bursts shows that /k/ and /t/ are differently affected by such co-production errors: co-production of tongue tip and tongue dorsum during intended /k/ results in typical /k/ spectra (and hence in tokens robustly classified as /k/), while co-productions during intended /t/ result in spectra with roughly equal prominence at both the mid-frequency (/k/-like) and high-frequency (/t/-like) ranges (and hence in tokens ambiguous between /k/ and /t/).
  • This outcome is not due to an articulatory timing difference, but to tongue dorsum constriction having an overall greater effect on the acoustic than a tongue tip constriction when the two are co-produced.

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  • (PMID = 20058990.001).
  • [ISSN] 1520-8524
  • [Journal-full-title] The Journal of the Acoustical Society of America
  • [ISO-abbreviation] J. Acoust. Soc. Am.
  • [Language] ENG
  • [Grant] United States / NIDCD NIH HHS / DC / R01 DC008780; United States / NIDCD NIH HHS / DC / R01DC008780-01
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2821172
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8. Chen YY, Chiang SY, Lin JG, Ma YS, Liao CL, Weng SW, Lai TY, Chung JG: Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9. Int J Oncol; 2010 May;36(5):1113-20
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  • [Title] Emodin, aloe-emodin and rhein inhibit migration and invasion in human tongue cancer SCC-4 cells through the inhibition of gene expression of matrix metalloproteinase-9.
  • Our previous studies also showed that emodin, aloe-emodin and rhein induced apoptosis in human tongue cancer SCC-4 cells.
  • Herein, we demonstrate that emodin, aloe-emodin and rhein inhibit the protein levels and activities of matrix metalloproteinase-2 (MMP-2) but did not affect gene expression of MMP-2, however, they inhibited the gene expression of MMP-9 and all also inhibited the migration and invasion of human tongue cancer SCC-4 cells.
  • MMP-9 (gelatinase-B) plays an important role and is the most associated with tumor migration, invasion and metastasis in various human cancers.
  • Our results provide new insight into the mechanisms by which emodin, aloe-emodin and rhein inhibit tongue cancers.
  • In conclusion, these findings suggest that molecular targeting of MMP-9 mRNA expression by emodin, aloe-emodin and rhein might be a useful strategy for chemo-prevention and/or chemo-therapeutics of tongue cancers.
  • [MeSH-major] Aloe / chemistry. Anthraquinones / pharmacology. Emodin / pharmacology. Gene Expression Regulation, Neoplastic. Matrix Metalloproteinase 9 / biosynthesis. Tongue Neoplasms / metabolism
  • [MeSH-minor] Cell Line, Tumor. Cell Movement. Drug Screening Assays, Antitumor. Humans. Matrix Metalloproteinase 2 / biosynthesis. Neoplasm Invasiveness. RNA, Messenger / metabolism. Urokinase-Type Plasminogen Activator / biosynthesis

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  • (PMID = 20372784.001).
  • [ISSN] 1791-2423
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Anthraquinones; 0 / RNA, Messenger; EC 3.4.21.73 / Urokinase-Type Plasminogen Activator; EC 3.4.24.24 / Matrix Metalloproteinase 2; EC 3.4.24.35 / Matrix Metalloproteinase 9; KA46RNI6HN / Emodin; YM64C2P6UX / rhein
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9. Kobashi Y, Fukuda M, Nakata M, Oka M: Coexistence of metastatic lung cancer and pulmonary tuberculosis diagnosed in the same cavity. Int J Clin Oncol; 2005 Oct;10(5):366-70
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  • A 79-year-old woman who had a past history of chronic renal failure 10 years earlier, tongue cancer (T2N2M0) 3 years earlier, and tuberculosis of the cervical lymph nodes 6 months earlier was suddenly admitted with the complaint of right chest pain on April 6, 2004.
  • Subsequently, it was determined that metastatic squamous cell carcinoma of the lung, corresponding to her tongue cancer, had invaded the visceral pleura adjacent to the largest cavitary lesion.
  • The epitheloid granuloma was found to be acid-fast bacilli-positive and a diagnosis of Mycobacterium tuberculosis pulmonary tuberculosis was made.
  • We report a rare case of the coexistence of metastatic lung cancer originating from tongue cancer and active pulmonary tuberculosis diagnosed in the same large cavitary lesion.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. Lung Neoplasms / diagnosis. Lung Neoplasms / secondary. Tongue Neoplasms / pathology. Tuberculosis, Pulmonary / diagnosis


10. Huang HJ, Ping FY, Hu JA, Zhao SF: [Cross-talk between Notch1 and epidermal growth factor receptor signalling in regulating cell proliferation of human tongue squamous carcinoma cells]. Zhonghua Yi Xue Za Zhi; 2009 Dec 15;89(46):3289-94
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  • [Title] [Cross-talk between Notch1 and epidermal growth factor receptor signalling in regulating cell proliferation of human tongue squamous carcinoma cells].
  • OBJECTIVE: To investigate the cross-talk between Notch1 and epidermal growth factor receptor (EGFR) signaling in regulating the cellular proliferation of human tongue squamous cell carcinoma (SCC).
  • METHODS: Human tongue SCC cell line Tca8113 cells was transiently transfected with the vector encoding exogenous intracellular fragment of Notch1 and the vector encoding the specific short hairpin RNA (shRNA) targeting EGFR respectively and were treated by AG1478, an inhibitor of receptor tyrosine kinases, for elucidating the effects of constitutive activation, EGFR gene silencing and blocking EGFR signaling upon cellular proliferation and expression of Notch1 and EGFR.
  • CONCLUSION: There might be a cross-talk of bi-directional control between Notch1 and EGFR signaling in regulating the cellular proliferation of human tongue SCC cells.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Receptor, Epidermal Growth Factor / metabolism. Receptor, Notch1 / metabolism. Signal Transduction. Tongue Neoplasms / metabolism
  • [MeSH-minor] Cell Line, Tumor. Cell Proliferation. Down-Regulation. Humans. Up-Regulation

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  • (PMID = 20193370.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / NOTCH1 protein, human; 0 / Receptor, Notch1; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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11. Mishima K, Nariai Y, Yoshimura Y: Etodolac, a selective cyclo-oxygenase-2 inhibitor, enhances carboplatin-induced apoptosis of human tongue carcinoma cells by down-regulation of FAP-1 expression. Oral Oncol; 2005 Jan;41(1):77-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Etodolac, a selective cyclo-oxygenase-2 inhibitor, enhances carboplatin-induced apoptosis of human tongue carcinoma cells by down-regulation of FAP-1 expression.
  • The human tongue well-differentiated squamous carcinoma cell line, SCC-25, shows Fas-dependent apoptosis by treatment with carboplatin (CBDCA).
  • [MeSH-major] Carboplatin / pharmacology. Carcinoma, Squamous Cell / pathology. Cyclooxygenase Inhibitors / pharmacology. Etodolac / pharmacology. Tongue Neoplasms / pathology
  • [MeSH-minor] Antineoplastic Agents / pharmacology. Apoptosis / drug effects. Blotting, Western. Carrier Proteins / metabolism. Down-Regulation / drug effects. Drug Synergism. Humans. Neoplasm Proteins / metabolism. Protein Tyrosine Phosphatase, Non-Receptor Type 13. Protein Tyrosine Phosphatases / metabolism. Reverse Transcriptase Polymerase Chain Reaction / methods. Tumor Cells, Cultured

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  • (PMID = 15598589.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Carrier Proteins; 0 / Cyclooxygenase Inhibitors; 0 / Neoplasm Proteins; 2M36281008 / Etodolac; BG3F62OND5 / Carboplatin; EC 3.1.3.48 / PTPN13 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 13; EC 3.1.3.48 / Protein Tyrosine Phosphatases
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12. Rukhadze I, Fenik VB, Benincasa KE, Price A, Kubin L: Chronic intermittent hypoxia alters density of aminergic terminals and receptors in the hypoglossal motor nucleus. Am J Respir Crit Care Med; 2010 Nov 15;182(10):1321-9
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  • We tested whether chronic intermittent hypoxia (CIH), a major pathogenic factor of OSA, affects aminergic innervation of XII motoneurons that innervate tongue-protruding muscles in a manner that could alter their airway-dilatory action.
  • MEASUREMENTS AND MAIN RESULTS: CIH-exposed rats had approximately 40% higher density of NE terminals and approximately 20% higher density of 5-HT terminals in the ventromedial quadrant of the XII nucleus, the region that controls tongue protruder muscles, than sham-treated rats.

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  • (PMID = 20622040.001).
  • [ISSN] 1535-4970
  • [Journal-full-title] American journal of respiratory and critical care medicine
  • [ISO-abbreviation] Am. J. Respir. Crit. Care Med.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL047600; United States / NHLBI NIH HHS / HL / R01 HL074385; United States / NHLBI NIH HHS / HL / HL-047600; United States / NHLBI NIH HHS / HL / HL-074385
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptor, Serotonin, 5-HT2A; 0 / Receptors, Adrenergic; 0 / Receptors, Adrenergic, alpha-1; 0 / Receptors, Serotonin; 333DO1RDJY / Serotonin; X4W3ENH1CV / Norepinephrine
  • [Other-IDs] NLM/ PMC3001268
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13. Friedman M, Wilson MN, Pulver TM, Golbin D, Lee GP, Gorelick G, Joseph NJ: Measurements of adult lingual tonsil tissue in health and disease. Otolaryngol Head Neck Surg; 2010 Apr;142(4):520-5
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  • SUBJECTS AND METHODS: Ninety-eight patients with CT scans including the tongue base and complete historical data regarding the presence or absence of symptoms, signs, and laboratory confirmation of LPR and/or OSAHS were included.
  • CONCLUSION: CT images including the tongue base allow precise measurement of LTT thickness.

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  • [Copyright] Copyright 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.
  • [CommentIn] Otolaryngol Head Neck Surg. 2010 Jul;143(1):172-3; author reply 173 [20620644.001]
  • (PMID = 20304271.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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14. Chan HL, Leong DJ, Fu JH, Yeh CY, Tatarakis N, Wang HL: The significance of the lingual nerve during periodontal/implant surgery. J Periodontol; 2010 Mar;81(3):372-7
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  • METHODS: Thirty lingual nerves from 18 cadaver heads were dissected, and the vertical distance from the lingual nerve to the mid-lingual cemento-enamel junctions of mandibular molars and premolars and the position where the lingual nerve left the lingual plate and moved toward the tongue were determined.
  • RESULTS: Seventy-five percent of lingual nerves turned toward the tongue at the first and second molar region.

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  • (PMID = 20192863.001).
  • [ISSN] 1943-3670
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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15. Chen YF, Lo YC, Lin WC, Lin CH, Chiang HJ, Chen JF, Shen WC: Transarterial embolization for control of bleeding in patients with head and neck cancer. Otolaryngol Head Neck Surg; 2010 Jan;142(1):90-4
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  • OBJECTIVE: This study evaluated the efficacy of transarterial embolization for the treatment of tumor bleeding in neck tumors following radiation or chemotherapy.
  • STUDY DESIGN: We performed a case series with chart review of 25 patients with clinically suspected tumor bleeding that occurred in the period between August 2003 and April 2007.
  • Carotid artery angiography was performed to detect tumor bleeding, and affected vessels were embolized using either Gelfoam sponge (or cubes), coils, microcoils, or a combination of these methods.
  • RESULTS: By angiography, patients showed tumor vessels with tumor stain (n = 13), extravasation of the contrast agent (n = 7), stenotic vessels (n = 5), pseudoaneurysm (n = 4), and arteriovenous shunt (n = 1).
  • Patients with tongue cancer had the longest average post-transarterial embolization hospital stay (21 days) and the highest incidence of aspiration pneumonia (3/9).
  • Patients with tongue cancer should be carefully monitored for aspiration pneumonia.

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  • (PMID = 20096229.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Kovács AF: Chemoembolization using cisplatin crystals as neoadjuvant treatment of oral cancer. Cancer Biother Radiopharm; 2005 Jun;20(3):267-79
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  • The highest response rates could be seen in T1-3 tumors and tumors of the oral tongue and floor of the mouth.
  • There have been 3.5% interventional and 10% local complications, which could be significantly reduced by the use of this procedure only in cancers of the oral tongue, floor of the mouth, and mandibular alveolar ridge.
  • [MeSH-minor] Crystallization. Female. Humans. Male. Middle Aged. Neoplasm Metastasis / pathology. Neoplasm Staging. Neoplasms, Second Primary / pathology. Time Factors. Treatment Outcome

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  • (PMID = 15989472.001).
  • [ISSN] 1084-9785
  • [Journal-full-title] Cancer biotherapy & radiopharmaceuticals
  • [ISO-abbreviation] Cancer Biother. Radiopharm.
  • [Language] eng
  • [Publication-type] Clinical Trial; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin
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17. Fronie A, Simionescu C, Vască V, Dumitrescu D, Fronie AS: Histopathological aspects of benign mesenchymal tumors located in "high risk areas" of the tongue. Rom J Morphol Embryol; 2010;51(1):97-104
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  • [Title] Histopathological aspects of benign mesenchymal tumors located in "high risk areas" of the tongue.
  • Although a series of premalignant or potentially malignant lesions are described in the tongue, there are many other lesions whose potential of degeneration can be determined by a prolonged action of irritant or carcinogenic factors.
  • Even if they are practically considered to be harmless, benign formations of mesenchymal origin with lingual location represent in the same time a neoplastic lesion under the influence of local and general factors, for a variable period of time.
  • When these structures are located in major risk areas from the oral cavity and in particular, those directly related to the tongue, special attention should be paid to their development.
  • In this study (conducted on a total of 16 cases of benign mesenchymal malignancies), we planned a histopathological evaluation of surgical excision samples obtained from interventions on lingual neoplasias, and harvested from areas with the highest risk for lingual cancer development (pelvilingual groove, the base of the tongue and the insertion of the anterior pillar) in order to assess the histopathological aspects in different types of lesions and the possible presence of degenerative changes.
  • [MeSH-major] Mesenchymoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 20191127.001).
  • [ISSN] 1220-0522
  • [Journal-full-title] Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
  • [ISO-abbreviation] Rom J Morphol Embryol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Romania
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18. Honda M, Hori Y, Shionoya Y, Nakada A, Sato T, Kobayashi T, Shimada H, Kida N, Nakamura T: Observation of the esophagus, pharynx and lingual root by gastrointestinal endoscopy with a percutaneous retrograde approach. World J Gastrointest Endosc; 2010 Aug 16;2(8):288-92
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  • If the tongue was manually pulled out forward, observation of the lingual root was possible.

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  • (PMID = 21160628.001).
  • [ISSN] 1948-5190
  • [Journal-full-title] World journal of gastrointestinal endoscopy
  • [ISO-abbreviation] World J Gastrointest Endosc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2999146
  • [Keywords] NOTNLM ; Gastrointestinal endoscopy / Lingual root / Mesopharynx / Percutaneous endoscopic gastrostomy / Retrograde observation
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19. Qureshi W, Hassan G, Khan GQ, Kadri SM, Kak M, Ahmad M, Tak S, Kundal DL, Hussain S, Rather AR, Masoodi I, Sikander S: Hoffmann's syndrome: a case report. Ger Med Sci; 2005;3:Doc05
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  • We describe the disorder in a 21 year old male, who got admitted with complaints of generalized weakness, cold intolerance, constipation, and hoarse voice, difficulty in walking and progressive enlargement of muscles of thighs and back with crampy pains for two years.
  • Examination revealed mild mental retardation, enlarged tongue, dry and rough skin, enlargement of thighs and back muscles, motor weakness in flexors of hips and knees with delayed relaxation of deep tendon reflexes.

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  • (PMID = 19675722.001).
  • [ISSN] 1612-3174
  • [Journal-full-title] German medical science : GMS e-journal
  • [ISO-abbreviation] Ger Med Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Other-IDs] NLM/ PMC2703243
  • [Keywords] NOTNLM ; hypothyroidism / myopathy / pseudohypertrophy
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20. San Gabriel A, Uneyama H, Maekawa T, Torii K: The calcium-sensing receptor in taste tissue. Biochem Biophys Res Commun; 2009 Jan 16;378(3):414-8
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  • Calcium is an essential nutrient that induces a distinctive taste quality, but the sensing mechanism of calcium in the tongue is poorly understood.

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  • (PMID = 19056349.001).
  • [ISSN] 1090-2104
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Calcium-Sensing; SY7Q814VUP / Calcium
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21. Nicolson SW, Human H: Bees get a head start on honey production. Biol Lett; 2008 Jun 23;4(3):299-301
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  • The doubling of sugar concentration suggests that nectar is regurgitated onto the tongue and evaporated during foraging and on the return flight.

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  • (PMID = 18364310.001).
  • [ISSN] 1744-9561
  • [Journal-full-title] Biology letters
  • [ISO-abbreviation] Biol. Lett.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2610047
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22. Logemann JA, Pauloski BR, Rademaker AW, Lazarus CL, Gaziano J, Stachowiak L, Newman L, MacCracken E, Santa D, Mittal B: Swallowing disorders in the first year after radiation and chemoradiation. Head Neck; 2008 Feb;30(2):148-58
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  • RESULTS: At baseline, patients had some swallow disorders, probably related to presence of their tumor.
  • At 3 months posttreatment, frequency of reduced tongue base retraction, slow or delayed laryngeal vestibule closure, and reduced laryngeal elevation increased from baseline.

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  • (PMID = 17786992.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / DE011921-05S2; United States / NCI NIH HHS / CA / P01 CA40007; United States / NCI NIH HHS / CA / P01 CA040007-15; United States / NCI NIH HHS / CA / CA040007-15; United States / NCI NIH HHS / CA / P50DE/CA11921; United States / NCI NIH HHS / CA / P01 CA040007; United States / NIDCR NIH HHS / DE / P50 DE011921-05S2
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS209104; NLM/ PMC2903205
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23. Hong KS, Lee JI, Hong SC: Neurological picture. Cerebral proliferative angiopathy associated with haemangioma of the face and tongue. J Neurol Neurosurg Psychiatry; 2010 Jan;81(1):36-7
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  • [Title] Neurological picture. Cerebral proliferative angiopathy associated with haemangioma of the face and tongue.
  • [MeSH-minor] Face. Female. Humans. Magnetic Resonance Angiography. Tongue. Young Adult

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  • (PMID = 20019220.001).
  • [ISSN] 1468-330X
  • [Journal-full-title] Journal of neurology, neurosurgery, and psychiatry
  • [ISO-abbreviation] J. Neurol. Neurosurg. Psychiatry
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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24. Lyons MJ, Khalil H, Kotecha BT: Surgical approaches to the tongue base in patients requiring radiofrequency treatment for snoring. Clin Otolaryngol; 2008 Apr;33(2):167-9
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  • [Title] Surgical approaches to the tongue base in patients requiring radiofrequency treatment for snoring.
  • [MeSH-major] Radiosurgery / instrumentation. Snoring / surgery. Tongue / anatomy & histology. Tongue / surgery

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  • (PMID = 18429895.001).
  • [ISSN] 1749-4486
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] England
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25. Liao G, Su Y, Zhang J, Hou J, Chen Y, Li M: Reconstruction of the tongue with reinnervated rectus abdominis musculoperitoneal flaps after hemiglossectomy. J Laryngol Otol; 2006 Mar;120(3):205-13
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  • [Title] Reconstruction of the tongue with reinnervated rectus abdominis musculoperitoneal flaps after hemiglossectomy.
  • Reconstruction of the tongue after glossectomy is a primary objective in the process of improving the life quality of patients suffering from tongue cancer.
  • We developed a new method of surgical reconstruction of the tongue after hemiglossectomy, with reinnervated rectus abdominis musculoperitoneal flaps.
  • Five patients underwent immediate reconstruction of the tongue with rectus abdominis musculoperitoneal flaps after hemiglossectomy.
  • Our experience indicates that reconstruction of the tongue with rectus abdominis musculoperitoneal flaps after hemiglossectomy is a suitable, cosmetically acceptable method.
  • [MeSH-major] Rectus Abdominis / transplantation. Surgical Flaps. Tongue / surgery. Tongue Neoplasms / surgery

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  • (PMID = 16549038.001).
  • [ISSN] 0022-2151
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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26. Reginald A, Sivapathasundharam B: Oral hairy leukoplakia: An exfoliative cytology study. Contemp Clin Dent; 2010 Jan;1(1):10-3
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  • Oral hairy leukoplakia (OHL) is a white, hyperplastic, vertically corrugated lesion that occurs on the lateral border of the tongue, usually unilateral.

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  • (PMID = 22114370.001).
  • [ISSN] 0976-2361
  • [Journal-full-title] Contemporary clinical dentistry
  • [ISO-abbreviation] Contemp Clin Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3220060
  • [Keywords] NOTNLM ; Exfoliative cytology / immunosuppressed / oral hairy leukoplakia
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27. Tannure PN, Valinoti AC, Maia LC: The use of a natural tooth crown following traumatic injuries in primary dentition. J Clin Pediatr Dent; 2009;33(4):275-8
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  • The treatment given could be considered an excellent rehabilitation option since it restores the esthetics and masticatory function, allows speech development, benefits oral hygiene and prevents the establishment of tongue habits and malocclusions.

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  • (PMID = 19725230.001).
  • [ISSN] 1053-4628
  • [Journal-full-title] The Journal of clinical pediatric dentistry
  • [ISO-abbreviation] J Clin Pediatr Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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28. Ghorbel IB, SioudDhrif A, Lamloum M, Trabelsi S, Habib Houman M: [Melkersson-Rosenthal syndrome. Report of five cases and review of the literature]. Tunis Med; 2006 Dec;84(12):816-20
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  • [Transliterated title] Syndrome de Melkersson-Rosenthal. A propos de cinq observations et revue de la littérature.
  • It is a rare entity and is characterized in its complete presentation, by the association of reccurent orofacial swelling, peripheral facial palsy and plicated tongue.
  • Incomplete forms are more frequent and more difficult to establish its diagnosis.
  • [MeSH-major] Melkersson-Rosenthal Syndrome / diagnosis

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  • (PMID = 17288289.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Tunisia
  • [Number-of-references] 20
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29. Bonfils P, de Preobrajenski N, Elouaret Y, Badoual C, Halimi P, Bigorgne C: [Granular cell tumours (Abrikossoff's tumour) of the parotid region]. Rev Laryngol Otol Rhinol (Bord); 2006;127(3):183-5
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  • [Title] [Granular cell tumours (Abrikossoff's tumour) of the parotid region].
  • [Transliterated title] Tumeur à cellules granuleuses (tumeur d'Abrikossoff) de la loge parotidienne.
  • BACKGROUND: Granular cell tumour (Abrikossoff's tumour) was first described by Abrikossoff in 1926.
  • These tumours are rare and usually presents as a solitary lesion, located mainly in the subcutaneous tissue of the head and neck, and in the oral cavity (tongue).
  • CASE REPORT: We report a rare case of a granular cell tumor of the parotid gland, in a 55-year old woman, who was referred with a left preauricular mass that had rapidly increased in size over 2 months.
  • [MeSH-major] Granular Cell Tumor / pathology. Granular Cell Tumor / physiopathology. Parotid Neoplasms / pathology. Parotid Neoplasms / physiopathology

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  • (PMID = 17007194.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 13
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30. Hiramatsu T, Nonoda T: [A case of tetanus showing limited mobility of the bilateral vocal cords]. Nihon Jibiinkoka Gakkai Kaiho; 2005 Sep;108(9):854-7
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  • She had lockjaw with tongue bite soon after a tracheostomy, and she was diagnosed as having tetanus.

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  • (PMID = 16218444.001).
  • [ISSN] 0030-6622
  • [Journal-full-title] Nihon Jibiinkoka Gakkai kaiho
  • [ISO-abbreviation] Nippon Jibiinkoka Gakkai Kaiho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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31. Dimtsas S, Theologie-Lygidakis N, Iatrou I: Intralingual dermoid cyst in an infant presenting swallowing and sleeping difficulties. J Clin Pediatr Dent; 2010;34(4):335-7
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  • The large size of the lesion and the subsequent enlargement of the tongue caused difficulties in swallowing and sleeping, symptoms which subsided after the surgical treatment.
  • [MeSH-major] Deglutition Disorders / etiology. Dermoid Cyst / congenital. Sleep Wake Disorders / etiology. Tongue Neoplasms / congenital

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  • (PMID = 20831136.001).
  • [ISSN] 1053-4628
  • [Journal-full-title] The Journal of clinical pediatric dentistry
  • [ISO-abbreviation] J Clin Pediatr Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Fuchs T, Bauer F, Paulsen P: Content of polyamines in by-products of slaughter pigs. Meat Sci; 2009 Sep;83(1):161-4
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  • A total of 210 samples of muscular tissues (heart, tongue, diaphragm and esophagus) and inner organs (liver, kidney, spleen, lung, salivary gland and pancreas) were tested.

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  • (PMID = 20416770.001).
  • [ISSN] 0309-1740
  • [Journal-full-title] Meat science
  • [ISO-abbreviation] Meat Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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33. Mendes-Araújo L, Rangel C, Domingues RC, Gasparetto EL: Case report. Atlantoaxial synovial cyst causing isolated unilateral hypoglossal nerve paralysis. Br J Radiol; 2010 Feb;83(986):e35-8
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  • We report the case of a 51-year-old woman who presented with dysarthria and tongue fasciculation.
  • [MeSH-minor] Aged. Aged, 80 and over. Diagnosis, Differential. Dysarthria / etiology. Fasciculation / etiology. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Tongue Diseases / etiology. Tongue Diseases / pathology

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  • (PMID = 20139255.001).
  • [ISSN] 1748-880X
  • [Journal-full-title] The British journal of radiology
  • [ISO-abbreviation] Br J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3473538
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34. Kljajić V, Jović R, Canji K, Nikolin B, Gavrilović M: [Surgical techniques and outcomes in the treatment of malignant tongue base tumors]. Med Pregl; 2007 Jan-Feb;60(1-2):49-53
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  • [Title] [Surgical techniques and outcomes in the treatment of malignant tongue base tumors].
  • INTRODUCTION: Prognosis of patients with malignant tongue base tumors is poor.
  • The aim of this investigation was to compare different treatment modalities in patients with malignant tongue base tumors.
  • Tongue base resection only was performed in 12 patients, tongue base resection with epiglottectomy in 20, tongue base resection with supraglottic laryngectomy in 13 and tongue base resection with total laryngectomy in 5 patients.
  • Five-year survival after combined surgical and radiation therapy was 35% CONCLUSION: Development of tongue base carcinoma is strongly associated with alcohol and tobacco consumption.
  • However, combined therapy is the therapy of choice in cases with tongue base carcinoma.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Carcinoma, Transitional Cell / surgery. Tongue Neoplasms / surgery

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  • (PMID = 17853711.001).
  • [ISSN] 0025-8105
  • [Journal-full-title] Medicinski pregled
  • [ISO-abbreviation] Med. Pregl.
  • [Language] srp
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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35. Sorrell J, Carmichael C, Chamlin S: Oral sucrose for pain relief in young infants with hemangiomas treated with intralesional steroids. Pediatr Dermatol; 2010 Mar-Apr;27(2):154-5
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  • We describe the successful use of an oral 24% sucrose solution given via needleless syringe to the anterior tip of the tongue or in combination with a pacifier as an analgesic during intralesional injection of infantile hemangioma.

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  • (PMID = 20537065.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adrenal Cortex Hormones; 0 / Analgesics; 1ZK20VI6TY / Triamcinolone; 57-50-1 / Sucrose
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36. Biswas A, Ghosh JK, Sinha MK, Basu K, Chatterjee S: Mohr-Claussen syndrome or oro-facial-digital syndrome (OFDS) type-II. J Pak Med Assoc; 2009 Jul;59(7):484-6
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  • The Mohr-Claussen syndrome or oro-facial-digital syndrome type II (OFD-II)] is characterised by tongue lobulation, midline cleft lip, high arched or cleft palate, broad nasal root with wide bifid nasal tip, hypertelorism, micrognathia, brachydactyly, syndactyly and polydactyly, bilateral reduplicated hallux, conductive hearing loss and normal intelligence.
  • In view of the different modes of inheritance and the different prognoses of the two oro-facio-digital syndromes, type 1 and type 2, it is important to establish a correct diagnosis in these patients.

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  • (PMID = 19579742.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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37. Friedman M, Schalch P: Surgery of the palate and oropharynx. Otolaryngol Clin North Am; 2007 Aug;40(4):829-43
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  • The authors present a method of clinical staging based on the position of the tongue relative to the soft palate as well as the size of the tonsils, aimed at identifying the most likely level of obstruction in patients who have OSAHS.

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  • (PMID = 17606025.001).
  • [ISSN] 0030-6665
  • [Journal-full-title] Otolaryngologic clinics of North America
  • [ISO-abbreviation] Otolaryngol. Clin. North Am.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 16
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38. Bhattarai S, Agrawal S, Rijal A, Dhali TK: Atypical varicella zoster as SJS-TEN overlap syndrome with involvement of palm and sole. Nepal Med Coll J; 2006 Mar;8(1):69-71
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  • Examination revealed erosions on the tongue, soft palate and genitalia with haemorrhagic crusts on the lips and nasal orifices.
  • [MeSH-major] Chickenpox / diagnosis. Foot / physiopathology. Hand / physiopathology. Herpesvirus 3, Human / isolation & purification. Stevens-Johnson Syndrome / diagnosis
  • [MeSH-minor] Acyclovir / therapeutic use. Comorbidity. Diagnosis, Differential. Humans. Infant. Male

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  • (PMID = 16827098.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Nepal
  • [Chemical-registry-number] X4HES1O11F / Acyclovir
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39. Ishii J, Kuriyama T, Komori T: Experimental study on the morphological and functional recovery following partial glossectomy in rabbits: a comparison between CO2 laser and electrocautery. Photomed Laser Surg; 2005 Feb;23(1):47-51
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  • METHODS: Partial glossectomy with the CO(2) laser or electrocautery in rabbits was performed to investigate changes in the body weight and tongue width after surgery.
  • There was a significant difference in the tongue width between groups 1 and 3 at each time point: 2 weeks (p < 0.05), 4 weeks (p < 0.01), and 8 weeks (p < 0.001) postoperatively.
  • Furthermore, there was a significant difference in the tongue width between groups 2 and 3 at 8 weeks (p < 0.02) postoperatively.
  • [MeSH-major] Electrocoagulation. Glossectomy / methods. Laser Therapy. Tongue / pathology. Wound Healing

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  • (PMID = 15782032.001).
  • [ISSN] 1549-5418
  • [Journal-full-title] Photomedicine and laser surgery
  • [ISO-abbreviation] Photomed Laser Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 142M471B3J / Carbon Dioxide
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40. Hessel AC, Moreno MA, Hanna EY, Roberts DB, Lewin JS, El-Naggar AK, Rosenthal DI, Weber RS: Compliance with quality assurance measures in patients treated for early oral tongue cancer. Cancer; 2010 Jul 15;116(14):3408-16
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Compliance with quality assurance measures in patients treated for early oral tongue cancer.
  • BACKGROUND: The objective of this study was to identify measurable parameters that provide quality data for assessing how well cancer care adheres to accepted treatment guidelines and is delivered to any given patient with oral tongue cancer.
  • METHODS: A retrospective chart review included 116 patients treated for T1-T2/N0-N1 squamous cell carcinoma (SCC) of the oral tongue between 1998 and 2003.
  • CONCLUSIONS: Overall compliance with documenting the 4 parameters designated as quality measures for treatment of oral tongue SCC was acceptable, thus demonstrating that it is possible to use these data for measuring effective cancer care.
  • [MeSH-major] Guideline Adherence. Quality Indicators, Health Care. Tongue Neoplasms / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Cancer Care Facilities. Female. Humans. Male. Middle Aged. Neck Dissection / standards. Neoplasm Staging / standards. Quality Assurance, Health Care. Radiotherapy, Adjuvant / standards. Treatment Outcome


41. Chim H, Salgado CJ, Mardini S, Chen HC: Reconstruction of mandibular defects. Semin Plast Surg; 2010 May;24(2):188-97
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  • Defects requiring reconstruction in the mandible are commonly encountered and may result from resection of benign or malignant lesions, trauma, or osteoradionecrosis.
  • Mandibular defects can be classified according to location and extent, as well as involvement of mucosa, skin, and tongue.

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  • (PMID = 22550439.001).
  • [ISSN] 1535-2188
  • [Journal-full-title] Seminars in plastic surgery
  • [ISO-abbreviation] Semin Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3324243
  • [Keywords] NOTNLM ; Bone flap / condyle / fibular flap / mandible / osseointegrated implant / osteocutaneous flap
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42. Friedman JW: The prophylactic extraction of third molars: a public health hazard. Am J Public Health; 2007 Sep;97(9):1554-9
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  • In addition, more than 11 million patient days of "standard discomfort or disability"--pain, swelling, bruising, and malaise--result postoperatively, and more than 11000 people suffer permanent paresthesia--numbness of the lip, tongue, and cheek--as a consequence of nerve injury during the surgery.

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  • (PMID = 17666691.001).
  • [ISSN] 1541-0048
  • [Journal-full-title] American journal of public health
  • [ISO-abbreviation] Am J Public Health
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1963310
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43. Ishibashi M, Tojo G, Watanabe M, Tamabuchi T, Masu T, Aiba S: Geographic tongue treated with topical tacrolimus. J Dermatol Case Rep; 2010 Dec 31;4(4):57-9
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  • [Title] Geographic tongue treated with topical tacrolimus.
  • BACKGROUND: Geographic tongue, or benign migratory glossitis, is usually an asymptomatic inflammatory disorder of the tongue mucosa of unknown etiology.
  • It is characterized by circinate, erythematous, ulcer-like lesions of the dorsum and lateral border of the tongue due to loss of filiform papillae of the tongue epithelium.
  • MAIN OBSERVATION: We describe herein two cases of adult patients with persistent and painful geographic tongue successfully treated with topical application of 0.1% tacrolimus ointment.
  • CONCLUSION: To our knowledge, this is the first report of successful treatment with topical 0.1% tacrolimus for symptomatic geographic tongue.
  • Clinical trials are needed to confirm the efficacy and the safety of topical tacrolimus in treating geographic tongue.

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  • (PMID = 21886753.001).
  • [ISSN] 1898-7249
  • [Journal-full-title] Journal of dermatological case reports
  • [ISO-abbreviation] J Dermatol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Poland
  • [Other-IDs] NLM/ PMC3157822
  • [Keywords] NOTNLM ; benign migratory glossitis / calcineurin inhibitors / geographic tongue / tacrolimus / treatment
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44. Yeates EM, Molfenter SM, Steele CM: Improvements in tongue strength and pressure-generation precision following a tongue-pressure training protocol in older individuals with dysphagia: three case reports. Clin Interv Aging; 2008;3(4):735-47
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Improvements in tongue strength and pressure-generation precision following a tongue-pressure training protocol in older individuals with dysphagia: three case reports.
  • Data are reported for three older participants in a pilot trial of a tongue-pressure training therapy.
  • During the experimental therapy protocol, participants performed isometric strength exercises for the tongue as well as tongue pressure accuracy tasks.
  • Biofeedback was provided using the Iowa Oral Performance Instrument (IOPI), an instrument that measures tongue pressure.
  • Treatment outcome measures show increased isometric tongue strength, improved tongue pressure generation accuracy, improved bolus control on videofluoroscopy, and improved functional dietary intake by mouth.
  • These preliminary results indicate that, for these three adults with dysphagia, tongue-pressure training was beneficial for improving both instrumental and functional aspects of swallowing.
  • [MeSH-major] Deglutition Disorders / rehabilitation. Exercise Therapy / methods. Tongue / physiopathology

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  • (PMID = 19281066.001).
  • [ISSN] 1176-9092
  • [Journal-full-title] Clinical interventions in aging
  • [ISO-abbreviation] Clin Interv Aging
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC2682406
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45. Marie I, Proux A, Levesque H, Bony-Rerolle S, Chenal P: Tongue involvement revealing sarcoidosis. QJM; 2008 Nov;101(11):909-11
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  • [Title] Tongue involvement revealing sarcoidosis.
  • [MeSH-major] Sarcoidosis / pathology. Tongue Diseases / pathology

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  • [CommentIn] QJM. 2009 Feb;102(2):149 [19028747.001]
  • (PMID = 18786978.001).
  • [ISSN] 1460-2393
  • [Journal-full-title] QJM : monthly journal of the Association of Physicians
  • [ISO-abbreviation] QJM
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] England
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46. Abo-Khatwa MM, Osman EZ, Hill PD, Lee BW, Osborne JE: Objective evaluation of tongue base snoring after the use of an oral appliance: a prospective case series. Clin Otolaryngol; 2008 Dec;33(6):592-5
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  • [Title] Objective evaluation of tongue base snoring after the use of an oral appliance: a prospective case series.
  • PARTICIPANTS: Fifteen patients with confirmed simple tongue base snoring had pre- and post-oral appliance objective assessment of their snoring loudness and duration at home.
  • CONCLUSION: Tongue base snorers had no significant reduction in their snoring with the oral appliances.
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Severity of Illness Index. Tongue. Treatment Outcome

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  • (PMID = 19126135.001).
  • [ISSN] 1749-4486
  • [Journal-full-title] Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery
  • [ISO-abbreviation] Clin Otolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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47. Sarlo K, Blackburn KL, Clark ED, Grothaus J, Chaney J, Neu S, Flood J, Abbott D, Bohne C, Casey K, Fryer C, Kuhn M: Tissue distribution of 20 nm, 100 nm and 1000 nm fluorescent polystyrene latex nanospheres following acute systemic or acute and repeat airway exposure in the rat. Toxicology; 2009 Sep 19;263(2-3):117-26
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  • Blood, perfusion fluid, bone marrow, brain, eyes, feces, gut, heart, kidney, liver, lung, muscle, skin, spleen, thymus, tongue, urine and uterus plus ovaries were collected for analysis.
  • Low numbers of particles were found in the circulation (blood, perfusion), bone marrow, brain, heart, liver and spleen but not in eye, muscle, skin, tongue, ovaries, uterus or urine.

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  • (PMID = 19615422.001).
  • [ISSN] 1879-3185
  • [Journal-full-title] Toxicology
  • [ISO-abbreviation] Toxicology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Polystyrenes; 9003-53-6 / styrofoam
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48. Pujary K, Rangarajan S, Nayak DR, Balakrishnan R, Ramakrishnan V: Hyalinizing clear cell carcinoma of the base of tongue. Int J Oral Maxillofac Surg; 2008 Jan;37(1):93-6
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  • [Title] Hyalinizing clear cell carcinoma of the base of tongue.
  • Hyalinizing clear cell carcinoma is a rare, low-grade neoplasm of the minor salivary glands.
  • There are only a few isolated cases reported in the literature involving the base of tongue.
  • A 57-year-old male patient presented with a lesion in the base of tongue, which was well enhanced on contrast computerized tomography scan.
  • [MeSH-major] Adenocarcinoma, Clear Cell / pathology. Salivary Gland Neoplasms / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17822882.001).
  • [ISSN] 0901-5027
  • [Journal-full-title] International journal of oral and maxillofacial surgery
  • [ISO-abbreviation] Int J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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49. Ong CM, Heard CM: Permeation of quinine across sublingual mucosa, in vitro. Int J Pharm; 2009 Jan 21;366(1-2):58-64
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  • The ventral surface of the tongue was significantly more permeable than porcine floor of the mouth (p<0.05) and there was no significant effect of freezing on the ventral surface of the tongue (p 0.2444).
  • The presence of saliva caused a decrease in the permeation of quinine across the ventral surface of the tongue by up to 68%.
  • [MeSH-minor] Administration, Sublingual. Animals. Chemistry, Pharmaceutical. Child. Chromatography, High Pressure Liquid. Humans. Mouth Mucosa / metabolism. Permeability. Saliva / metabolism. Swine. Tongue / metabolism

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  • (PMID = 18835345.001).
  • [ISSN] 0378-5173
  • [Journal-full-title] International journal of pharmaceutics
  • [ISO-abbreviation] Int J Pharm
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antimalarials; 0 / Drug Carriers; 0 / beta-Cyclodextrins; 94035-02-6 / 2-hydroxypropyl-beta-cyclodextrin; A7V27PHC7A / Quinine
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50. Patil R, Nayak S, Munshi M, Bobhate S: Scrape cytology in rare case of hairy tongue. J Cytol; 2009 Apr;26(2):91-3
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  • [Title] Scrape cytology in rare case of hairy tongue.
  • Hairy tongue (HT) is a benign condition that causes concern over its abnormal appearance.
  • HT is most commonly seen in adults and is seen as an abnormal coating of the tongue due to hyperkeratosis of filiform lingual papillae.
  • Cytological scraping of the lesion on the tongue was done which showed squamous cells, extraneous material, bacterial colonies, fungal bodies, and hair-like projections, which are the hall mark of the disease.

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  • (PMID = 21938163.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168029
  • [Keywords] NOTNLM ; Cytology / hairy lesions of the tongue / hairy tongue
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51. Shen S, Pang J, Seneviratne S, Ashton MW, Corlett RJ, Taylor GI: A comparative anatomical study of brachioradialis and flexor carpi ulnaris muscles: implications for total tongue reconstruction. Plast Reconstr Surg; 2008 Mar;121(3):816-29
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  • [Title] A comparative anatomical study of brachioradialis and flexor carpi ulnaris muscles: implications for total tongue reconstruction.
  • BACKGROUND: Total or subtotal glossectomy following resection of intraoral tumors causes significant morbidity.
  • The authors compared the neurovascular anatomy of the brachioradialis and flexor carpi ulnaris to assess their suitability as donor muscles together with overlying skin for functional total or subtotal tongue reconstruction.
  • CONCLUSION: The authors delineated the anatomical advantages of the flexor carpi ulnaris over the brachioradialis for total or subtotal tongue reconstruction.
  • [MeSH-major] Muscle, Skeletal / anatomy & histology. Reconstructive Surgical Procedures. Tongue / surgery

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  • (PMID = 18317131.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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52. Ryu M, Ueda T, Saito T, Yasui M, Ishihara K, Sakurai K: Oral environmental factors affecting number of microbes in saliva of complete denture wearers. J Oral Rehabil; 2010 Mar;37(3):194-201
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Age, sex, un-stimulated salivary flow rate, pH and viscosity of saliva, histatin level in saliva, tongue coating status, tongue pressure, denture plaque status, material of denture base, duration of edentulism, frequency of self oral health care and number of cigarettes per day were also investigated as oral environmental factors.
  • Correlation and stepwise logistic regression analyses revealed associations between un-stimulated salivary flow rate, tongue coating status, denture plaque status or frequency of self oral health care and number of total anaerobic bacteria.
  • [MeSH-minor] Age Factors. Aged. Bacteria, Anaerobic / classification. Candida / classification. Colony Count, Microbial. Dental Materials / chemistry. Dental Plaque Index. Female. Histatins / analysis. Humans. Hydrogen-Ion Concentration. Male. Oral Hygiene. Pressure. Secretory Rate / physiology. Sex Factors. Smoking. Time Factors. Tongue / microbiology. Tongue / physiology. Viscosity

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  • (PMID = 20050985.001).
  • [ISSN] 1365-2842
  • [Journal-full-title] Journal of oral rehabilitation
  • [ISO-abbreviation] J Oral Rehabil
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dental Materials; 0 / Histatins
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53. Kulawik M, Godynicki S: Vallate papillae in the domestic rabbit (Oryctolagus cuniculus f. domestica). Pol J Vet Sci; 2007;10(1):47-50
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  • On the root of the tongue in the rabbit there are two symmetrically located vallate papillae, covered by nonkeratinized stratified squamous epithelium.
  • The outer wall of the vallate papillae is gradually transformed with no visible boundary into the surface of the root of the tongue devoid of papillae.
  • The results of this study show the structure of vallate papillae on the tongue of adult rabbits, at the same time indicating differences in their structure in comparison to the vallate papillae of other animal species.
  • [MeSH-major] Rabbits / anatomy & histology. Tongue / ultrastructure

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  • (PMID = 17388025.001).
  • [ISSN] 1505-1773
  • [Journal-full-title] Polish journal of veterinary sciences
  • [ISO-abbreviation] Pol J Vet Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Poland
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54. Hiraba H, Sato T: Cortical control of mastication in cats. 2. Deficits of masticatory movements following a lesion in the motor cortex. Somatosens Mot Res; 2005 Sep;22(3):183-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cats with the entire lesion in area P showed a decrease of food intake rates associated with abnormal tongue protrusion and wide jaw-opening, fluctuation of masticatory start, and prolongation of masticatory and food intake periods.
  • Abnormal movements of tongue and jaw did not recover, although their prolongation and fluctuation returned to normal levels in one month.
  • These findings suggest that area P may regulate accurate and suitable tongue and jaw movements during mastication depending on cortical processing.
  • [MeSH-minor] Animals. Behavior, Animal / drug effects. Cats. Electromyography. Female. Male. Motor Neurons / drug effects. Motor Neurons / physiology. Tongue / physiology

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  • (PMID = 16338826.001).
  • [ISSN] 0899-0220
  • [Journal-full-title] Somatosensory & motor research
  • [ISO-abbreviation] Somatosens Mot Res
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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55. Ko HB, Lee DY, Lee YC: Severe bradycardia during suspension laryngoscopy performed after tracheal intubation using a direct laryngoscope with a curved blade -A case report-. Korean J Anesthesiol; 2010 Aug;59(2):116-8
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  • The tip of the curved blade of the direct laryngoscope is positioned at the vallecula (between the base of the tongue and the pharyngeal surface of the epiglottis) during tracheal intubation, while the blade tip of the suspension laryngoscope lifts the laryngeal surface of the epiglottis or supraglottic area during surgery.

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  • (PMID = 20740217.001).
  • [ISSN] 2005-7563
  • [Journal-full-title] Korean journal of anesthesiology
  • [ISO-abbreviation] Korean J Anesthesiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2926427
  • [Keywords] NOTNLM ; Bradycardia / Remifentanil / Suspension laryngoscopy / Vagal reflex
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56. Goodman BP, Schrader SL: Radiation-induced cranial neuropathies manifesting as baroreflex failure and progressive bulbar impairment. Neurologist; 2009 Mar;15(2):102-4
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  • INTRODUCTION: Baroreflex failure and bulbar palsy have been rarely reported as potential complications of radiotherapy for head and neck tumors.
  • EMG showed myokymic discharges in the tongue, and marked orthostatic hypotension was noted on tilt-table testing.

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  • (PMID = 19276789.001).
  • [ISSN] 1074-7931
  • [Journal-full-title] The neurologist
  • [ISO-abbreviation] Neurologist
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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57. Kawakami T, Fukai K, Sowa J, Ishii M, Teramae H, Kanazawa K: Case of cheilitis granulomatosa associated with apical periodontitis. J Dermatol; 2008 Feb;35(2):115-9
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  • Neither facial nerve palsy nor fissuring of the tongue was present.

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  • (PMID = 18271809.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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58. Emsen IM: The use of metatarsal bone grafts in the treatment of saddle nose deformities. Aesthetic Plast Surg; 2006 Nov-Dec;30(6):705-7; discussion 708
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  • It is slotted into the metatarsal bone in a tongue-in-groove manner and sutured to it through a drill hole in the bone.

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  • [RetractionIn] Aesthetic Plast Surg. 2009 Jul;33(4):677 [19582503.001]
  • (PMID = 17077952.001).
  • [ISSN] 0364-216X
  • [Journal-full-title] Aesthetic plastic surgery
  • [ISO-abbreviation] Aesthetic Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Retracted Publication
  • [Publication-country] United States
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59. Baroni A, Capristo C, Rossiello L, Faccenda F, Satriano RA: Lingual traumatic ulceration (Riga-Fede disease). Int J Dermatol; 2006 Sep;45(9):1096-7
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  • An 11-month-old male infant was referred to our clinic because of a painful ulcer of approximately 5 months' duration on the ventral surface of the tongue (Fig. 1).
  • No biopsy was performed in view of the age of the infant, the particular site of the lesion, and the clinical evidence of diagnosis.
  • [MeSH-major] Oral Ulcer / pathology. Tongue / injuries. Tongue Diseases / pathology

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  • (PMID = 16961520.001).
  • [ISSN] 0011-9059
  • [Journal-full-title] International journal of dermatology
  • [ISO-abbreviation] Int. J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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60. Gedrange T, Boening K, Harzer W: Orthodontic implants as anchorage appliances for unilateral mesialization: a case report. Quintessence Int; 2006 Jun;37(6):485-91
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  • Slight irritations of the tongue were registered in the first 2 weeks of use of the palatal implant.

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  • (PMID = 16752705.001).
  • [ISSN] 0033-6572
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Dental Implants
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61. Kodama M, Khanal A, Habu M, Iwanaga K, Yoshioka I, Tanaka T, Morimoto Y, Tominaga K: Ultrasonography for intraoperative determination of tumor thickness and resection margin in tongue carcinomas. J Oral Maxillofac Surg; 2010 Aug;68(8):1746-52
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  • [Title] Ultrasonography for intraoperative determination of tumor thickness and resection margin in tongue carcinomas.
  • PURPOSE: Exact estimation of tumor thickness and the status of the resection margin in tongue carcinoma are important prognostic factors for local recurrence, subclinical nodal metastasis, and survival.
  • This study aims to evaluate the accuracy of intraoral ultrasonography-guided measurement of tumor thickness and define an adequate intraoperative resection margin in squamous cell carcinomas of the tongue.
  • MATERIALS AND METHODS: In this prospective study, 13 patients with presurgical, biopsy-proven, clinical T1N0 or T2N0 tongue squamous cell carcinomas who underwent a partial glossectomy were examined preoperatively with ultrasonography to assess tumor thickness under general anesthesia.
  • Nine cases underwent resection by a conventional method, whereas we introduced elastic needles with a metal core to mark a deep surgical margin of 10 mm from the deepest tumor invasion front under ultrasonographic monitoring as a new technique in the remaining 4 cases.
  • The ultrasonographic tumor thickness measurements corresponded well with those of histologic sections, with a consistency ratio of 91.4% to 98.2% (Pearson correlation coefficient = 0.981, P < .05).
  • CONCLUSION: Intraoperative ultrasonography is a reliable method to objectively evaluate tumor thickness and surgical margin clearance.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Carcinoma, Squamous Cell / ultrasonography. Glossectomy / methods. Tongue Neoplasms / surgery. Tongue Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Imaging, Three-Dimensional. Intraoperative Care. Linear Models. Male. Middle Aged. Neoplasm Staging. Prospective Studies. Reproducibility of Results. Statistics, Nonparametric. Tissue Embedding. Tumor Burden

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  • [Copyright] Copyright 2010 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20031291.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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62. Lim YC, Lee JS, Koo BS, Kim SH, Kim YH, Choi EC: Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: elective neck dissection versus observation. Laryngoscope; 2006 Mar;116(3):461-5
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  • [Title] Treatment of contralateral N0 neck in early squamous cell carcinoma of the oral tongue: elective neck dissection versus observation.
  • OBJECTIVES/HYPOTHESIS: Prophylactic treatment of contralateral N0 neck in early squamous cell carcinoma (SCC) of the oral tongue is a controversial issue.
  • The aim of this study was to analyze the rates of occult metastases and their prognostic effects in stage I and stage II SCC of the oral tongue, and to compare the results of elective neck dissection to observation of the contralateral N0 neck in the treatment of these patients.
  • METHODS: We reviewed the medical records of 54 patients who were treated at Severance Hospital from 1992 to 2003 and had been diagnosed with stage I or stage II SCC of the oral tongue and had not received prior treatment.
  • CONCLUSIONS: This study showed that ipsilateral elective neck management is indicated for stage I and II SCC of the oral tongue.
  • On the other hand, our series suggests that contralateral occult lymph node metastasis was unlikely in early-stage oral tongue SCC, and that there was no survival benefit for patients who underwent elective neck dissection in place of observation.
  • Thus, it may not harmful to observe the contralateral N0 neck in the treatment of early oral tongue cancer.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Neck Dissection / methods. Tongue Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Follow-Up Studies. Glossectomy. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Radiotherapy, Adjuvant. Retrospective Studies. Treatment Outcome


63. Shetty SJ, Bansal S, Kulkarni SR, Desai R, Bablani D, Prasad P: Benign teratoma of the tongue in a neonate: a case report and review of the literature. Pediatr Dent; 2010 May-Jun;32(3):245-9
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  • [Title] Benign teratoma of the tongue in a neonate: a case report and review of the literature.
  • The purpose of this report was to describe the case of a benign teratoma originating from the tongue in a male neonate.
  • [MeSH-major] Teratoma / congenital. Tongue Neoplasms / congenital

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  • (PMID = 20557709.001).
  • [ISSN] 0164-1263
  • [Journal-full-title] Pediatric dentistry
  • [ISO-abbreviation] Pediatr Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 22
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64. Kataria P, Passey JC, Agarwal AK: Lymphangioma circumscriptum of the tongue: successful treatment using intralesional bleomycin. J Laryngol Otol; 2009 Dec;123(12):1390-2
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  • [Title] Lymphangioma circumscriptum of the tongue: successful treatment using intralesional bleomycin.
  • OBJECTIVE: We report a case of lymphangioma circumscriptum of the tongue, a very rare site of occurrence, which was successfully managed with intralesional bleomycin therapy.
  • METHOD: We present a case report and review of available literature regarding lymphangioma circumscriptum of the tongue and the role of bleomycin therapy.
  • RESULTS: The patient was a 19-year-old man with a long-standing lesion involving the tongue, who presented with spontaneous, episodic bleeding over the previous few months.
  • A diagnosis of lymphangioma circumscriptum was established on biopsy.
  • This case had a very rare site of occurrence, the tongue, and was successfully managed with conservative treatment, using intralesional bleomycin alone.
  • [MeSH-major] Antibiotics, Antineoplastic / administration & dosage. Bleomycin / administration & dosage. Lymphangioma / drug therapy. Tongue Neoplasms / drug therapy

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  • (PMID = 19545460.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibiotics, Antineoplastic; 11056-06-7 / Bleomycin
  • [Number-of-references] 12
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65. Roldán S, Herrera D, O'Connor A, González I, Sanz M: A combined therapeutic approach to manage oral halitosis: a 3-month prospective case series. J Periodontol; 2005 Jun;76(6):1025-33
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  • At baseline, all subjects completed a questionnaire and carried out an examination including full-mouth organoleptic and volatile sulfur compound (VSC) levels and the Winkel tongue coating index.
  • Standardized microbiological samples of subgingival plaque, unstimulated saliva, and tongue coating were obtained for culture analysis.
  • The treatment protocol included supragingival prophylaxis; instructions in oral hygiene (toothbrushing, interproximal cleaning, and tongue scraping); and gargling with a mouthrinse containing chlorhexidine, cetylpiridinium chloride, and zinc lactate.
  • RESULTS: Statistically significant reductions in organoleptic scores (P <0.001), VSC levels (P <0.05), and tongue coating index (P <0.05) were observed after 1 and 3 months.
  • Total anaerobic counts were significantly reduced at all three locations after 1 month (P <0.05), and in samples from tongue coating and subgingival plaque at 3 months (P <0.05).
  • Aerobic counts were significantly reduced in saliva at 1 month (P <0.05), and the anaerobic/aerobic ratio significantly increased in the tongue samples.
  • The proposed clinical protocol significantly affected the microbial composition in tongue coating, saliva, and subgingival microflora.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Dental Plaque / microbiology. Epidemiologic Methods. Female. Humans. Lactates / therapeutic use. Male. Middle Aged. Mouthwashes / therapeutic use. Saliva / microbiology. Sulfur / analysis. Tongue / microbiology. Treatment Outcome. Zinc / therapeutic use

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  • (PMID = 15948701.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Anti-Infective Agents, Local; 0 / Lactates; 0 / Mouthwashes; 70FD1KFU70 / Sulfur; CUB7JI0JV3 / Cetylpyridinium; J41CSQ7QDS / Zinc; R4KO0DY52L / Chlorhexidine
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66. Sugi M, Yanishi M, Shimada O, Kawakita S, Murota T, Shikata N: [Neuroendocrine differentiation and metastasized to brain stem, intraorbit and base of tongue in prostate cancer during hormonal treatment: a case report]. Hinyokika Kiyo; 2008 May;54(5):373-6
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  • [Title] [Neuroendocrine differentiation and metastasized to brain stem, intraorbit and base of tongue in prostate cancer during hormonal treatment: a case report].
  • Prostatic neuroendocrine (NE) carcinoma is a rare disease and the NE differentiation in prostate cancer is characterized by poor prognosis, rapidly progressing tumor and an androgen-independent state, for which there is currently no successful therapy.
  • Herein, we report a case of NE differentiatiated prostatic cancer, which metastasized to the base of tongue, intraorbit and brain stem.
  • This is the first Japanese report of prostate cancer metastasis to the brain stem and base of the tongue.
  • [MeSH-major] Adenocarcinoma / pathology. Brain Stem Neoplasms / secondary. Carcinoma, Neuroendocrine / pathology. Cell Differentiation. Orbital Neoplasms / secondary. Prostatic Neoplasms / pathology. Tongue Neoplasms / secondary
  • [MeSH-minor] Androgen Antagonists / therapeutic use. Drug Resistance, Neoplasm. Humans. Male. Middle Aged


67. Patel M, LaSala C, Tulikangas P, O'Sullivan DM, Steinberg AC: Use of a beef tongue model and instructional video for teaching residents fourth-degree laceration repair. Int Urogynecol J; 2010 Mar;21(3):353-8
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  • [Title] Use of a beef tongue model and instructional video for teaching residents fourth-degree laceration repair.
  • INTRODUCTION AND HYPOTHESIS: This study seeks to compare the utility of the beef tongue model versus an instructional video in teaching obstetric and gynecology residents how to repair a fourth-degree laceration.
  • METHODS: Twenty-seven residents were randomized to participate in a workshop with a beef tongue model or assigned to watch an instructional video on repair of fourth-degree lacerations and read a chapter on the repair.
  • CONCLUSIONS: An instructional video or beef tongue model and textbook chapter on fourth-degree laceration repair can improve skills in repair of a fourth-degree laceration among residents with no experience in these repairs.
  • [MeSH-minor] Anal Canal / injuries. Animals. Cattle. Female. Humans. Pregnancy. Tongue. Video Recording

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  • [Cites] Obstet Gynecol. 2007 Feb;109(2 Pt 1):289-94 [17267826.001]
  • [Cites] Fam Med. 2006 Sep;38(8):542-4 [16944382.001]
  • [Cites] Am J Obstet Gynecol. 2006 Nov;195(5):1463-7 [16846576.001]
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  • (PMID = 19924368.001).
  • [ISSN] 1433-3023
  • [Journal-full-title] International urogynecology journal
  • [ISO-abbreviation] Int Urogynecol J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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68. Chang MC, Chan CP, Ho YS, Lee JJ, Lin PS, Lin BR, Huang YL, Hahn LJ, Yeh HW, Wang YJ, Jeng JH: Signaling pathways for induction of platelet aggregation by SAS tongue cancer cells--a mechanism of hematogenous metastasis. J Oral Pathol Med; 2009 May;38(5):434-40
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  • [Title] Signaling pathways for induction of platelet aggregation by SAS tongue cancer cells--a mechanism of hematogenous metastasis.
  • BACKGROUND: Tongue cancer metastasis is mainly through blood stream and possibly associated with tumor cell-induced platelet aggregation (TCIPA).
  • METHODS: Platelet aggregation was induced by different amounts of SAS tongue cancer cells with/without inhibitors and the latent period for induction of platelet aggregation was recorded.
  • CONCLUSIONS: These results suggest that tongue cancer cells may induce TCIPA and enhance tumor metastasis.
  • Betel quid chewing may potentially promote tongue cancer metastasis.
  • [MeSH-major] Areca. Plant Extracts / pharmacology. Platelet Aggregation / physiology. Thromboplastin / metabolism. Tongue Neoplasms / metabolism
  • [MeSH-minor] Coculture Techniques. Epithelial Cells / metabolism. Gene Expression Profiling. Gingiva / cytology. Gingiva / metabolism. Humans. Mouth Mucosa / cytology. Mouth Mucosa / metabolism. Neoplasm Metastasis. Neoplasm Proteins / metabolism. Neoplasm Proteins / pharmacology. RNA, Messenger / analysis. Second Messenger Systems / drug effects. Second Messenger Systems / physiology. Signal Transduction / drug effects. Signal Transduction / physiology. Statistics, Nonparametric. Time Factors. Tumor Cells, Cultured

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  • (PMID = 18811671.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 0 / Plant Extracts; 0 / RNA, Messenger; 9035-58-9 / Thromboplastin
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69. Asami T, Aoyagi H, Yoshizawa H, Wanichanon C, Iwasaki S: Immunohistochemical expression of type II collagen in the lingual mucosa of rats during organogenesis of the tongue. Arch Oral Biol; 2008 Jul;53(7):622-8
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  • [Title] Immunohistochemical expression of type II collagen in the lingual mucosa of rats during organogenesis of the tongue.
  • OBJECTIVES: We examined the timing of the appearance and distribution of type II collagen as a possible component of the extracellular matrix that is involved in the morphogenesis of the rat tongue.
  • RESULTS: Immunoreactivity specific for type II collagen was scattered on cells over a wide area of the mesenchymal connective tissue of the fetal tongue on day 15 after conception (E15), when the lingual epithelium was composed of one or two layers of cuboidal cells.
  • In addition, immunoreactivity was widely distributed in the connective tissue around the lingual muscle, as myogenesis in the tongue advanced.
  • CONCLUSION: Type II collagen appeared not only in the connective tissue of the lamina propria as the morphogenesis of filiform papillae occurred and the lingual epithelium became keratinized but also in the endomysium and perimysium around the lingual muscle after myogenesis of the tongue is complete at P0.
  • [MeSH-major] Collagen Type II / biosynthesis. Mouth Mucosa / embryology. Organogenesis / physiology. Tongue / embryology

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  • (PMID = 18313641.001).
  • [ISSN] 0003-9969
  • [Journal-full-title] Archives of oral biology
  • [ISO-abbreviation] Arch. Oral Biol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Collagen Type II; 62229-50-9 / Epidermal Growth Factor; EC 2.7.10.1 / Receptor, Epidermal Growth Factor
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70. Kezirian EJ, Goldberg AN: Hypopharyngeal surgery in obstructive sleep apnea: an evidence-based medicine review. Arch Otolaryngol Head Neck Surg; 2006 Feb;132(2):206-13
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  • DESIGN: We performed a MEDLINE search of English-language articles or abstracts using the keywords sleep and surgery in combination with any of the following terms: hypopharynx, tongue, tongue base, epiglottis, genioglossus, advancement, mortised, genioplasty, glossectomy, tongue radiofrequency, hyoepiglottoplasty, hyoid, suspension, and stabilization.

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  • (PMID = 16490881.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 50
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71. Junqueira JC, Colombo CE, Martins Jda S, Koga Ito CY, Carvalho YR, Jorge AO: Experimental candidosis and recovery of Candida albicans from the oral cavity of ovariectomized rats. Microbiol Immunol; 2005;49(3):199-207
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  • Four animals from each group were not inoculated with yeast suspension and were submitted to tongue dorsum morphologic analysis by optical and scanning electron microscopy.
  • The development of candidosis in the tongue dorsum was observed by optical and scanning electron microscopy in the periods of 6 hr, 24 hr, 7 days and 15 days after the last inoculation.
  • The tongue dorsum of sham-ovariectomized and ovariectomized rats, not infected by Candida, presented normal aspect.
  • [MeSH-minor] Animals. Disease Models, Animal. Estradiol / blood. Female. Microscopy, Electron, Scanning. Mouth Mucosa / microbiology. Mouth Mucosa / ultrastructure. Ovariectomy. Progesterone / blood. Rats. Rats, Wistar. Tongue / microbiology. Tongue / ultrastructure

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  • (PMID = 15781993.001).
  • [ISSN] 0385-5600
  • [Journal-full-title] Microbiology and immunology
  • [ISO-abbreviation] Microbiol. Immunol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 4G7DS2Q64Y / Progesterone; 4TI98Z838E / Estradiol
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72. Karacay S, Akin E, Ortakoglu K, Bengi AO: Dynamic MRI evaluation of tongue posture and deglutitive movements in a surgically corrected open bite. Angle Orthod; 2006 Nov;76(6):1057-65
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  • [Title] Dynamic MRI evaluation of tongue posture and deglutitive movements in a surgically corrected open bite.
  • Tongue thrust usually develops in the presence of anterior open bite in order to achieve anterior valve function.
  • In the literature, tongue thrust is described both as the result and the cause of open bite.
  • If it is an adaptation to malocclusion, then tongue posture and deglutitive tongue movements should change after treatment.
  • Pretreatment and posttreatment dynamic magnetic resonance imaging (MRI) revealed that tongue tip was retruded behind the incisors and contact of the tongue with the palate increased.
  • Advancement of the mandible, correction of open bite, and an increase in PAS affected not only the tongue posture and deglutitive movements, but also the breathing pattern of the patient.
  • [MeSH-major] Deglutition / physiology. Mandibular Advancement. Open Bite / surgery. Tongue / physiology
  • [MeSH-minor] Adult. Airway Obstruction / physiopathology. Airway Obstruction / surgery. Cephalometry. Humans. Magnetic Resonance Imaging / methods. Male. Malocclusion, Angle Class II / physiopathology. Malocclusion, Angle Class II / surgery. Mouth Breathing / physiopathology. Mouth Breathing / surgery. Movement. Orthodontics, Corrective. Pharynx / anatomy & histology. Preoperative Care. Tongue Habits / therapy

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  • (PMID = 17090175.001).
  • [ISSN] 0003-3219
  • [Journal-full-title] The Angle orthodontist
  • [ISO-abbreviation] Angle Orthod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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73. Wang Y, Han Y, Li Y, Chen JX, Zhang XH: Isolation of Photobacterium damselae subsp. piscicida from diseased tongue sole (Cynoglossus semilaevis Gunther) in China. Wei Sheng Wu Xue Bao; 2007 Oct;47(5):763-8
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  • [Title] Isolation of Photobacterium damselae subsp. piscicida from diseased tongue sole (Cynoglossus semilaevis Gunther) in China.
  • During the summer of 2006, an epizootic occurred among cultured tongue sole (Cynoglossus semilaevis Gunther) in a fish farm in Qingdao, China.
  • The diseased tongue sole exhibited haemorrhaging of the basal fin, yellowed kidney and ulceration of the body surface.
  • Pathogenicity assays revealed that WY06 was virulent to tongue sole and zebrafish (Danio rerio) by intraperitoneal injection challenge, with the LD50 being calculated as 5.5 x 10(3) cfu/g of fish (5.2 x 10(5) cfu/fish) and 1.9 x 10(3) cfu/g of fish (8.9 x 10(2) cfu/fish) respectively.

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  • (PMID = 18062245.001).
  • [ISSN] 0001-6209
  • [Journal-full-title] Wei sheng wu xue bao = Acta microbiologica Sinica
  • [ISO-abbreviation] Wei Sheng Wu Xue Bao
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / RNA, Ribosomal, 16S
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74. Zhou X, Temam S, Chen Z, Ye H, Mao L, Wong DT: Allelic imbalance analysis of oral tongue squamous cell carcinoma by high-density single nucleotide polymorphism arrays using whole-genome amplified DNA. Hum Genet; 2005 Dec;118(3-4):504-7
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  • [Title] Allelic imbalance analysis of oral tongue squamous cell carcinoma by high-density single nucleotide polymorphism arrays using whole-genome amplified DNA.
  • By utilizing the Affymetrix GeneChip Chromosome Copy Number Tool, the allelic imbalance profiles for the advanced stage oral tongue squamous cell carcinoma (OTSCC) were generated based on 10 K and 100 K SNP mapping array results.
  • [MeSH-major] Allelic Imbalance. Carcinoma, Squamous Cell / genetics. Oligonucleotide Array Sequence Analysis. Polymorphism, Single Nucleotide. Tongue Neoplasms / genetics

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  • [Cites] J Biol Chem. 1993 Feb 5;268(4):2719-26 [8428945.001]
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  • (PMID = 16193324.001).
  • [ISSN] 0340-6717
  • [Journal-full-title] Human genetics
  • [ISO-abbreviation] Hum. Genet.
  • [Language] eng
  • [Grant] United States / NIDCR NIH HHS / DE / K22 DE014847; United States / NCI NIH HHS / CA / P01 CA106451; United States / NIDCR NIH HHS / DE / R01 DE015970; United States / NCI NIH HHS / CA / R03 CA114688; United States / NIDCR NIH HHS / DE / R03 DE016569
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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75. Talebian A, Tazhibi M, Iranpoor R, Semyari H, Taherzadeh M: Relationship between tonsil odor and oral malodor: a clinical study on 48 Iranian patients. J Breath Res; 2008 Mar;2(1):017016
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  • After the baseline evaluations the subjects were instructed to scrape the surface of the tongue daily and rinse with a zinc-containing mouthwash twice daily for 1 month.

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  • (PMID = 21386160.001).
  • [ISSN] 1752-7155
  • [Journal-full-title] Journal of breath research
  • [ISO-abbreviation] J Breath Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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76. Tekcicek M, Tavil B, Cakar A, Pinar A, Unal S, Gumruk F: Oral and dental findings in children with Fanconi anemia. Pediatr Dent; 2007 May-Jun;29(3):248-52
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  • Examination of the oral cavity revealed that: (a) 3 children (12%) had a coated tongue; and (b) 1 (4%) had papillary atrophy.
  • [MeSH-major] Fanconi Anemia / complications. Mouth Diseases / diagnosis. Tooth Diseases / diagnosis
  • [MeSH-minor] Adolescent. Anodontia / diagnosis. Atrophy. Buffers. Child. Child, Preschool. Dental Care. Dental Caries / diagnosis. Female. Follow-Up Studies. Gingivitis / diagnosis. Humans. Hydrogen-Ion Concentration. Male. Saliva / physiology. Saliva / secretion. Secretory Rate / physiology. Tongue / pathology. Tooth Abnormalities / diagnosis. Tooth Eruption, Ectopic / diagnosis. Tooth, Supernumerary / diagnosis. Toothbrushing


77. Lee JS, Pei-Lin Ng P, Tao M, Lim WT: Paraneoplastic pemphigus resembling linear IgA bullous dermatosis. Int J Dermatol; 2006 Sep;45(9):1093-5
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  • Severe erosions with hemorrhagic crusts on the lips, tongue, and buccal mucosa were seen.
  • A presumptive diagnosis of paraneoplastic pemphigus was made.
  • [MeSH-minor] Aged. China. Diagnosis, Differential. Fatal Outcome. Humans. Male. Skin / immunology. Skin / pathology


78. Karaman E, Saritzali G, Ozcora E: Rhabdomyoma of the tonsillar fossa. J Craniofac Surg; 2009 Jul;20(4):1207-9
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  • Extracardiac rhabdomyomas are very uncommon tumors comprising approximately 2% of the neoplasms of striated muscle origin.
  • The most common reported head and neck subsites are the floor of the mouth, tongue, palate, lips, and cheeks.
  • We report an unusual presentation of rhabdomyoma that should be included in the differential diagnosis of tumors presenting as a large tonsillar fossa mass.
  • The cytologic and immunohistochemical differential diagnoses of this tumor are also discussed.
  • [MeSH-major] Rhabdomyoma / diagnosis. Tonsillar Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Endoscopy. Humans. Magnetic Resonance Imaging. Male. Middle Aged

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  • (PMID = 19506521.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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79. O'Donnell V, Pacheco JM, Gregg D, Baxt B: Analysis of foot-and-mouth disease virus integrin receptor expression in tissues from naïve and infected cattle. J Comp Pathol; 2009 Aug-Oct;141(2-3):98-112
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  • Integrin alpha(V)beta(6) was expressed by epithelial cells in tissues that are important sites for FMDV replication (i.e. tongue and coronary band).
  • Integrin alpha(V)beta(3) was detected in epithelium of all tissues examined except tongue.
  • Although integrin alpha(V)beta(3) has been shown to be a receptor for FMDV, no expression of alpha(V)beta(3) was associated with FMDV-positive keratinocytes in the tongue.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Foot-and-Mouth Disease / virology. Foot-and-Mouth Disease Virus / physiology. Integrins / metabolism. Receptors, Virus / metabolism
  • [MeSH-minor] Animals. Cattle. Coronary Vessels / metabolism. Coronary Vessels / pathology. Coronary Vessels / virology. Epithelial Cells / metabolism. Epithelial Cells / pathology. Epithelial Cells / virology. Fluorescent Antibody Technique, Indirect / methods. Fluorescent Antibody Technique, Indirect / veterinary. Integrin alphaVbeta3. Microscopy, Confocal / methods. Microscopy, Confocal / veterinary. Mouth Mucosa / metabolism. Mouth Mucosa / pathology. Mouth Mucosa / virology. Tongue / metabolism. Tongue / pathology. Tongue / virology

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  • (PMID = 19515380.001).
  • [ISSN] 1532-3129
  • [Journal-full-title] Journal of comparative pathology
  • [ISO-abbreviation] J. Comp. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Integrin alphaVbeta3; 0 / Integrins; 0 / Receptors, Virus; 0 / integrin alphavbeta6
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80. Ludescher B, Knebel C, Hoffmann J, Schwenzer N, Claussen CD, Küper K: [Volumetry of the human tongue by MRI]. Mund Kiefer Gesichtschir; 2006 Mar;10(2):101-5
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  • [Title] [Volumetry of the human tongue by MRI].
  • [Transliterated title] MR-Volumetrie der Zunge zur Abschätzung der individuellen Zungengrösse.
  • AIM: The purpose of this study was to determine the volume of the tongue using MRI.
  • The correlation of the individual volume of the tongue and the size of the oral cavity was to be investigated.
  • MATERIAL AND METHODS: To analyze the tongue volume we combined coronal and sagittal data acquisition, which divided the tongue virtually into two lateral and one medial part.
  • In 20 probands (m/f 7/13, average age of 36.3 years) the volume of the tongue was determined.
  • RESULTS: There was a significant linear regression between the tongue volume and height of the mouth cavity.
  • This correlation can be used to calculate the normal volume of a patient's tongue.
  • DISCUSSION: Volumetry of the tongue can be carried out by means of MRI without application of injurious X-rays.
  • It can be employed before as well as after tongue reduction surgeries for therapy control.
  • The individual ideal tongue volume can be determined easily by determination of the height of the oral cavity.
  • [MeSH-major] Image Processing, Computer-Assisted. Magnetic Resonance Imaging. Mouth / anatomy & histology. Tongue / anatomy & histology

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  • (PMID = 16489462.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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81. Lv AP, Wang YY: [Methodological thoughts on clinical efficacy evaluation with multiple clinical trials]. Zhongguo Zhong Yao Za Zhi; 2006 Aug;31(16):1384-5
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  • The differences, whether positively or negatively related to the efficacy, could be obtained from all information including symptom evaluation, tongue appearance, pulse feeling and biological parameters with non-linear and other statistical methods.

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  • (PMID = 17061564.001).
  • [ISSN] 1001-5302
  • [Journal-full-title] Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
  • [ISO-abbreviation] Zhongguo Zhong Yao Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Drugs, Chinese Herbal
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82. Chung JC, Ng RW: A huge tongue lipoma. Otolaryngol Head Neck Surg; 2007 Nov;137(5):830-1
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  • [Title] A huge tongue lipoma.
  • [MeSH-major] Lipoma / pathology. Tongue Neoplasms / pathology

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  • (PMID = 17967655.001).
  • [ISSN] 0194-5998
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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83. Lüers JC, Isfort P, Bovenschulte H, Beutner D: [Unilateral tongue atrophy and articulation difficulties]. HNO; 2010 Jan;58(1):68-71
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  • [Title] [Unilateral tongue atrophy and articulation difficulties].
  • She reported that her tongue felt "heavy and inert".
  • Clinically, right-sided atrophy of the tongue and deflection of the tongue to the right were observed.
  • MRI demonstrated atrophy of the right tongue musculature with fatty degeneration, as well as an oval, smoothly edged lesion which showed marked contrast-medium uptake with a "salt and pepper" configuration in the region of the right jugular foramen.
  • The diagnosis was hypoglossal paresis due to ipsilateral jugular paraganglioma (Fisch classification C1).
  • Following embolization of the feeding vessels of the paraganglioma, the tumor was completely resected, including the hypoglossal nerve which ran through the tumor.
  • [MeSH-major] Paraganglioma / complications. Paraganglioma / surgery. Speech Disorders / etiology. Speech Disorders / prevention & control. Tongue Diseases / etiology. Tongue Diseases / prevention & control. Vascular Neoplasms / complications. Vascular Neoplasms / surgery
  • [MeSH-minor] Adult. Atrophy / diagnosis. Atrophy / etiology. Atrophy / prevention & control. Female. Humans. Treatment Outcome

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  • (PMID = 19727629.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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84. Kakarala K, Bhattacharyya N: Survival in oral cavity minor salivary gland carcinoma. Otolaryngol Head Neck Surg; 2010 Jul;143(1):122-6
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  • The hard palate and gums were the most common subsites involved (87.6%), followed by lip (7.2%) and tongue (5.2%).
  • At presentation, T1 and T4 tumors predominated (42.6% and 35.2%, respectively); 93.4 percent were N0.
  • [MeSH-minor] Age Factors. Cohort Studies. Female. Humans. Male. Middle Aged. Neoplasm Staging. Retrospective Studies. SEER Program. Sex Factors. Survival Rate. United States / epidemiology

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  • [Copyright] 2010 American Academy of Otolaryngology-Head and Neck Surgery Foundation. Published by Mosby, Inc. All rights reserved.
  • (PMID = 20620630.001).
  • [ISSN] 1097-6817
  • [Journal-full-title] Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • [ISO-abbreviation] Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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85. Liu HL, Chan JY, Wei WI: The changing role of pectoralis major flap in head and neck reconstruction. Eur Arch Otorhinolaryngol; 2010 Nov;267(11):1759-63
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  • In the early study period (1998-June 2003), out of the 119 PM flap reconstructions, 106 (89%) were performed for immediate reconstruction after resection of head and neck tumour, while 10 (8%) were performed as salvage procedures for complication after tumour resection e.g. failure of free flap, pharyngocutaneous fistula.
  • For immediate reconstruction after tumour extirpation, 51 flaps (48%) were performed for reconstruction of the tongue in the early study period, while only 14 (24%) were performed in the late study period.

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  • (PMID = 20461392.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
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  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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86. Soncini JA, Kanasi E, Lu SC, Nunn ME, Henshaw MM, Tanner AC: Oral microbiota of children in a school-based dental clinic. Anaerobe; 2010 Jun;16(3):278-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • There was a higher species detection frequency from teeth than tongue samples.

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  • [Copyright] 2009 Elsevier Ltd. All rights reserved.
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  • (PMID = 19879369.001).
  • [ISSN] 1095-8274
  • [Journal-full-title] Anaerobe
  • [ISO-abbreviation] Anaerobe
  • [Language] ENG
  • [Grant] United States / NIDCR NIH HHS / DE / R01 DE015847-04; United States / NIDCR NIH HHS / DE / T32 DE007151-14; United States / NIDCR NIH HHS / DE / T32 DE007151; United States / NIDCR NIH HHS / DE / DE014264-070004; United States / NIDCR NIH HHS / DE / U54 DE014264; United States / NIDCR NIH HHS / DE / DE-014264; United States / NIDCR NIH HHS / DE / R01 DE015847; United States / NIDCR NIH HHS / DE / U54 DE014264-070004; United States / NIDCR NIH HHS / DE / T32 DE-007151; United States / NIDCR NIH HHS / DE / DE-015847; United States / NIDCR NIH HHS / DE / DE007151-14
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] England
  • [Other-IDs] NLM/ NIHMS203886; NLM/ PMC2881591
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87. Teguh DN, Levendag PC, Noever I, van Rooij P, Voet P, van der Est H, Sipkema D, Sewnaik A, Baatenburg de Jong RJ, de la Bije D, Schmitz PI: Treatment techniques and site considerations regarding dysphagia-related quality of life in cancer of the oropharynx and nasopharynx. Int J Radiat Oncol Biol Phys; 2008 Nov 15;72(4):1119-27
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  • RESULTS: Most dysphagia problems were observed in the base of tongue tumors.

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  • (PMID = 18472364.001).
  • [ISSN] 1879-355X
  • [Journal-full-title] International journal of radiation oncology, biology, physics
  • [ISO-abbreviation] Int. J. Radiat. Oncol. Biol. Phys.
  • [Language] eng
  • [Publication-type] Controlled Clinical Trial; Journal Article
  • [Publication-country] United States
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88. Nyst HJ, van Veen RL, Tan IB, Peters R, Spaniol S, Robinson DJ, Stewart FA, Levendag PC, Sterenborg HJ: Performance of a dedicated light delivery and dosimetry device for photodynamic therapy of nasopharyngeal carcinoma: phantom and volunteer experiments. Lasers Surg Med; 2007 Sep;39(8):647-53
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  • Shielding of the risk area such as the soft palate and tongue was effective.

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  • [Copyright] 2007 Wiley-Liss, Inc
  • (PMID = 17886277.001).
  • [ISSN] 0196-8092
  • [Journal-full-title] Lasers in surgery and medicine
  • [ISO-abbreviation] Lasers Surg Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Photosensitizing Agents
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89. Zhang GG, Lee W, Bausell B, Lao L, Handwerger B, Berman B: Variability in the traditional Chinese medicine (TCM) diagnoses and herbal prescriptions provided by three TCM practitioners for 40 patients with rheumatoid arthritis. J Altern Complement Med; 2005 Jun;11(3):415-21
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  • OBJECTIVE: To ascertain if previous findings of low levels of agreement of Traditional Chinese Medicine (TCM) pattern diagnoses made by TCM practitioners in patients with rheumatoid arthritis (RA) were a function of practitioner differences or would be replicated with a different sample of clinicians, and to examine the relationship between TCM diagnosis and herbal treatment plans.
  • Patients filled out questionnaires and physical examinations, including observations of the tongue and palpation of radial pulse, were conducted by the 3 practitioners.
  • Each practitioner then provided both a TCM diagnosis and an herbal prescription.
  • The degree to which the herbal prescriptions agreed with textbook recommended practice for each TCM diagnosis was 91.7% (range, 85-100%).
  • The most commonly used TCM assessments in arriving at these diagnoses were inquiry about factors affecting pain and pulse diagnosis.
  • No statistically significant differences were found between this study and our previous study regarding the level of agreement on TCM diagnosis.
  • No association was found between the diagnostic methods used and the consistency of diagnosis.
  • [MeSH-major] Arthritis, Rheumatoid / diagnosis. Arthritis, Rheumatoid / therapy. Clinical Competence. Drugs, Chinese Herbal / therapeutic use. Medicine, Chinese Traditional / utilization
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Humans. Maryland. Middle Aged. Physical Examination / standards. Prospective Studies. Quality Assurance, Health Care. Reproducibility of Results. Research Design

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  • (PMID = 15992224.001).
  • [ISSN] 1075-5535
  • [Journal-full-title] Journal of alternative and complementary medicine (New York, N.Y.)
  • [ISO-abbreviation] J Altern Complement Med
  • [Language] eng
  • [Grant] United States / NCCIH NIH HHS / AT / AT00590; United States / NCRR NIH HHS / RR / M01 RR16500
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Drugs, Chinese Herbal
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90. Gilbert RJ, Napadow VJ, Gaige TA, Wedeen VJ: Anatomical basis of lingual hydrostatic deformation. J Exp Biol; 2007 Dec;210(Pt 23):4069-82
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  • The mammalian tongue is believed to fall into a class of organs known as muscular hydrostats, organs for which muscle contraction both generates and provides the skeletal support for motion.
  • We propose that the myoarchitecture of the tongue, consisting of intricate arrays of muscular fibers, forms the structural basis for hydrostatic deformation.
  • Image data obtained in this manner suggest that the tongue consists of a complex juxtaposition of muscle fibers oriented in orthogonal arrays, which provide the basis for multidirectional contraction and isovolemic deformation.
  • [MeSH-major] Tongue / abnormalities. Tongue / anatomy & histology

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  • (PMID = 18025008.001).
  • [ISSN] 0022-0949
  • [Journal-full-title] The Journal of experimental biology
  • [ISO-abbreviation] J. Exp. Biol.
  • [Language] eng
  • [Grant] United States / NIDCD NIH HHS / DC / R01-DC05604; United States / NIMH NIH HHS / MH / R01-MH64044
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Review
  • [Publication-country] England
  • [Number-of-references] 50
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91. Haas AN, Silveira EM, Rösing CK: Effect of tongue cleansing on morning oral malodour in periodontally healthy individuals. Oral Health Prev Dent; 2007;5(2):89-94
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  • [Title] Effect of tongue cleansing on morning oral malodour in periodontally healthy individuals.
  • PURPOSE: The aim of this randomised single-blind, cross-over trial was to assess the effect of tongue cleansing on morning oral malodour in periodontally healthy subjects.
  • In one of these test periods, subjects were instructed to clean their tongues with a tongue scraper 2-3 times a day.
  • VSC levels did not change significantly during the 4 days, independent of tongue cleansing (Friedman, p > 0.05).
  • Only at day 3 did the use of the tongue scraper lead to a significantly lower level of VSC compared with controls (131.1 ppb and 199.3 ppb respectively).
  • During the whole experimental period, there were also no significant changes in organoleptic scores when individuals used or did not use the tongue scraper.
  • CONCLUSION: Tongue cleansing with a scraper was unable to prevent morning oral malodour in the absence of tooth cleaning in periodontally healthy individuals.
  • [MeSH-major] Biofilms. Halitosis / therapy. Oral Hygiene / methods. Tongue

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  • (PMID = 17722433.001).
  • [ISSN] 1602-1622
  • [Journal-full-title] Oral health & preventive dentistry
  • [ISO-abbreviation] Oral Health Prev Dent
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Sulfur Compounds
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92. Vanheule S, Desmet M, Meganck R: What the heart thinks, the tongue speaks: a study on depression and lexical choice. Psychol Rep; 2009 Apr;104(2):473-81
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  • [Title] What the heart thinks, the tongue speaks: a study on depression and lexical choice.
  • [MeSH-major] Depressive Disorder / diagnosis. Depressive Disorder / psychology. Linguistics. Personality Inventory / statistics & numerical data
  • [MeSH-minor] Adult. Affective Symptoms / diagnosis. Ambulatory Care. Cognition Disorders / diagnosis. Diagnostic and Statistical Manual of Mental Disorders. Female. Humans. Language. Male. Metaphor. Psychiatric Status Rating Scales. Psychometrics. Surveys and Questionnaires

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  • (PMID = 19610477.001).
  • [ISSN] 0033-2941
  • [Journal-full-title] Psychological reports
  • [ISO-abbreviation] Psychol Rep
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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93. Pueyo C, Royo Y, Maldonado J, Skrabski R, Gris F, Landeyro J, Bardají C: Double cervical cyst derived from a single thyroglossal duct tract. J Pediatr Surg; 2008 Apr;43(4):748-50
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  • This type of cyst can be located anywhere between the base of the tongue and the sternal manubrium.
  • Intrathyroid cysts of the thyroglossal duct, though uncommon, should be included in the differential diagnosis of thyroid cysts in children.
  • [MeSH-major] Thyroglossal Cyst / diagnosis

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  • (PMID = 18405727.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Sano D, Choi S, Milas ZL, Zhou G, Galer CE, Su YW, Gule M, Zhao M, Zhu Z, Myers JN: The effect of combination anti-endothelial growth factor receptor and anti-vascular endothelial growth factor receptor 2 targeted therapy on lymph node metastasis: a study in an orthotopic nude mouse model of squamous cell carcinoma of the oral tongue. Arch Otolaryngol Head Neck Surg; 2009 Apr;135(4):411-20
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  • [Title] The effect of combination anti-endothelial growth factor receptor and anti-vascular endothelial growth factor receptor 2 targeted therapy on lymph node metastasis: a study in an orthotopic nude mouse model of squamous cell carcinoma of the oral tongue.
  • OBJECTIVE: To evaluate the therapeutic effect of treatment with a combination of the monoclonal antibodies to the vascular endothelial growth factor receptor (DC101) and the epidermal growth factor receptor (cetuximab) in an orthotopic nude mouse model of metastatic squamous cell carcinoma of the oral tongue (SCCOT).
  • Tumors were resected at necropsy, and immunohistochemical and immunofluorescent staining were performed.
  • MAIN OUTCOME MEASURES: Tumor size, bioluminescence, animal survival, and percentage of animals with lymph node metastasis.
  • RESULTS: At the conclusion of the treatment period, the mean tumor volumes in the cetuximab alone and the DC101 plus cetuximab groups had decreased significantly compared with those that received the placebo control (68% [P = .002] and 84% [P < .001], respectively).

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  • (PMID = 19380367.001).
  • [ISSN] 1538-361X
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P50 CA097007-010002; United States / NCI NIH HHS / CA / P30 CA016672; United States / NCI NIH HHS / CA / P50 CA097007; United States / NCI NIH HHS / CA / P30 CA016672-24; United States / NCI NIH HHS / CA / CA16672; United States / NCI NIH HHS / CA / CA060374-10; United States / NCI NIH HHS / CA / T32 CA060374; United States / NCI NIH HHS / CA / T32CA060374; United States / NCI NIH HHS / CA / T32 CA060374-10; United States / NCI NIH HHS / CA / CA097007-010002; United States / NCI NIH HHS / CA / P50 CA097007A
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / Antineoplastic Agents; 0 / DC101 monoclonal antibody; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptors, Vascular Endothelial Growth Factor; PQX0D8J21J / Cetuximab
  • [Other-IDs] NLM/ NIHMS219138; NLM/ PMC2914603
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95. Smittkamp SE, Brown JW, Stanford JA: Time-course and characterization of orolingual motor deficits in B6SJL-Tg(SOD1-G93A)1Gur/J mice. Neuroscience; 2008 Jan 24;151(2):613-21
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  • We measured orolingual motor function by placing thirsty mice in a customized operant chamber that allows for measurement of tongue force and lick rhythm as animals lick water from an isometric disc.
  • Bulbar involvement appeared much later, with tongue motility being affected by 100 days of age.
  • Tongue force was affected by 115 days of age.

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  • (PMID = 18061359.001).
  • [ISSN] 0306-4522
  • [Journal-full-title] Neuroscience
  • [ISO-abbreviation] Neuroscience
  • [Language] ENG
  • [Grant] United States / NIA NIH HHS / AG / R01 AG023549; United States / NIA NIH HHS / AG / K02 AG026491-02; United States / NIA NIH HHS / AG / AG026491; United States / NIA NIH HHS / AG / AG023549-05; United States / NIA NIH HHS / AG / AG026491-02; United States / NIA NIH HHS / AG / R01 AG023549-05; United States / NIA NIH HHS / AG / K02 AG026491; United States / NICHD NIH HHS / HD / P30 HD002528; United States / NIA NIH HHS / AG / AG023549
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.15.1.- / superoxide dismutase 1; EC 1.15.1.1 / Superoxide Dismutase
  • [Other-IDs] NLM/ NIHMS39188; NLM/ PMC2244802
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96. Berg T: A structural account of phonological paraphasias. Brain Lang; 2005 Jul;94(1):104-29
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  • The notion of structure holds the key to an understanding of the differences among the following three types of data: slips of the tongue, slips of the pen (defined as errors committed by healthy, competent adults), and paraphasias.
  • A comparison of these three data types reveals that slips of the pen and paraphasias display striking similarities whereas slips of the tongue stand apart.
  • Hence, slips of the tongue are highly sensitive to structural effects.

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  • [ErratumIn] Brain Lang. 2006 Mar;96(3):330
  • [RepublishedIn] Brain Lang. 2006 Mar;96(3):331-56 [16615177.001]
  • (PMID = 15896388.001).
  • [ISSN] 0093-934X
  • [Journal-full-title] Brain and language
  • [ISO-abbreviation] Brain Lang
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 129
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97. Mehndiratta MM: Trigeminal motor neuropathy with tongue fasciculations in a patient with chronic inflammatory demyelinating polyradiculoneuropathy. J Clin Neurosci; 2010 Oct;17(10):1355-6
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  • [Title] Trigeminal motor neuropathy with tongue fasciculations in a patient with chronic inflammatory demyelinating polyradiculoneuropathy.

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  • (PMID = 20615708.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Scotland
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98. Terakawa Y, Ichinohe T, Kaneko Y: Rocuronium and vecuronium do not affect mandibular bone marrow and masseter muscular blood flow in rabbits. J Oral Maxillofac Surg; 2010 Jan;68(1):15-20
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  • Observed variables were systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, common carotid artery blood flow, tongue mucosal blood flow, oxygen partial pressure of the mandibular bone marrow, and oxygen partial pressure of the masseter muscle.
  • Tongue mucosal blood flow in the vecuronium group was decreased depending on the infusion rate.
  • Vecuronium decreased tongue mucosal blood flow depending on the infusion rate.
  • [MeSH-minor] Anesthesia, General. Animals. Blood Pressure / drug effects. Heart Rate / drug effects. Infusions, Intravenous. Male. Oxygen / metabolism. Partial Pressure. Rabbits. Tongue / blood supply

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  • (PMID = 20006149.001).
  • [ISSN] 1531-5053
  • [Journal-full-title] Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
  • [ISO-abbreviation] J. Oral Maxillofac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Androstanols; 0 / Neuromuscular Nondepolarizing Agents; 7E4PHP5N1D / Vecuronium Bromide; S88TT14065 / Oxygen; WRE554RFEZ / rocuronium
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99. Møller AR, Osburn LL, Cohen-Gadol AA: Hemilingual spasm: pathophysiology. Neurosci Lett; 2009 Sep 18;461(2):76-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • During a microvascular decompression operation to treat hemilingual spasm, transcranial stimulation elicited a delayed electromyographic (EMG) response from the tongue.
  • This late tongue EMG response resembles those found in facial muscles of the patients with hemifacial spasm (HFS).
  • The results of the present study indicate that the EMG signs of hemilingual spasm are similar to those of HFS and that the tongue spasms are most likely caused by hyperactivity of the hypoglossal motonucleus.
  • [MeSH-major] Hypoglossal Nerve Diseases / physiopathology. Spasm / physiopathology. Tongue / blood supply. Tongue / innervation

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  • (PMID = 19520147.001).
  • [ISSN] 1872-7972
  • [Journal-full-title] Neuroscience letters
  • [ISO-abbreviation] Neurosci. Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
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100. Xue M, Gao XH, Pang XN, Bai YX: [Ultrasonographic evaluation of tongue movement during swallowing in severe skeletal Class III malocclusion in adult patients]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2009 May;44(5):289-92
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ultrasonographic evaluation of tongue movement during swallowing in severe skeletal Class III malocclusion in adult patients].
  • OBJECTIVE: To investigate the tongue movement during swallowing in skeletal Class III adult patients using M-mode ultrasonography combined with cushion scanning technique.
  • METHODS: Tongue movement during swallowing in 20 skeletal Class III adult patients (11 females, 9 males, mean age 20.5 years) and 11 healthy adults (8 females, 3 males, mean age 23.5 years) was examined with M-mode ultrasonography combined with cushion scanning technique.
  • CONCLUSIONS: The skeletal Class III adult patients had distinctly different tongue movements during swallowing.
  • [MeSH-major] Deglutition. Malocclusion, Angle Class III / ultrasonography. Tongue / ultrasonography

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  • (PMID = 19575987.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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