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6. Ustunyurt E, Gungor T, Iskender C, Ustunyurt BO, Bilge U, Mollamahmutoglu L: Tumor markers in mature cystic teratomas of the ovary. Arch Gynecol Obstet; 2009 Feb;279(2):145-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tumor markers in mature cystic teratomas of the ovary.
  • OBJECTIVE: The objective of this study was to evaluate the serum levels of tumor markers in patients with ovarian mature cystic teratomas.
  • CONCLUSION: Serum CA 19-9 has the highest positivity rate among other tumor markers in ovarian mature cystic teratomas.
  • [MeSH-major] Biomarkers, Tumor / blood. Ovarian Neoplasms / blood. Teratoma / blood

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  • [ErratumIn] Arch Gynecol Obstet. 2015 Jan;291(1):231. Emin, Ustunyurt [corrected to Ustunyurt, Emin]; Tayfun, Gungor [corrected to Gungor, Tayfun]; Cantekin, Iskender [corrected to Iskender, Cantekin]; Ozlem, Ustunyurt Basak [corrected to Ustunyurt, Basak Ozlem]; Umit, Bilge [corrected to Bilge, Umit]; Leyla, Mollamahmutoglu [corrected to Mollamahmutoglu, Leyla] [25284628.001]
  • (PMID = 18506458.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen; 0 / Mucin-1; 0 / alpha-Fetoproteins
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7. Kao TH, Shen CC, Chen CC, Kwan PH: "Primary" benign retroperitoneal and intraspinal dumbbell-shaped cystic teratoma: case report. Spine (Phila Pa 1976); 2005 Aug 1;30(15):E439-43
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  • [Title] "Primary" benign retroperitoneal and intraspinal dumbbell-shaped cystic teratoma: case report.
  • STUDY DESIGN: A case of unusual dumbbell-shaped cystic teratoma is presented.
  • OBJECTIVES: To investigate and describe an unusual case of retroperitoneal cystic teratoma with spinal invasion in an adult.
  • SUMMARY OF BACKGROUND DATA: Primary benign cystic teratomas of the retroperitoneum are rare.
  • In this report, by presenting a case of cystic teratoma with such extension, the origin of the tumor, and the value of computerized tomography and magnetic resonance imaging (MRI) in the preoperative diagnosis and surgical approach for the extended lesion are discussed.
  • Preoperative computerized tomography and MRI of the thoracic and lumbar spines showed a dumbbell-shaped tumor, with the solid part residing in the right retroperitoneum near the neuroforamen of the L2-L3 spines and the cystic part extending into the spinal canal.
  • RESULTS: Diagnosis of cystic teratoma was confirmed by pathologic examination.
  • CONCLUSIONS: Total surgical removal of tumor is an ideal treatment for retroperitoneal and intraspinal dumbbell-shaped cystic teratoma.
  • [MeSH-major] Lumbar Vertebrae / radiography. Retroperitoneal Space / radiography. Spinal Cord Neoplasms / radiography. Teratoma / radiography

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  • (PMID = 16094263.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Gozar H, Ardelean M, Giliga V, Turcu M, Bancu S: A case of a giant sacrococcygeal teratoma. Chirurgia (Bucur); 2010 Jul-Aug;105(4):537-40
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  • [Title] A case of a giant sacrococcygeal teratoma.
  • Sacrococygeal teratomas are congenital tumors of newborns, originate from one or more of the three germinal layers.
  • Most sacrococygeal teratomas are found in newborns, infants and children youger than 4 years.
  • The prenatal ultrasound exams have increased the number of sacrococygeal teratomas presenting in fetuses.
  • Radical resection, including the coccyx must be performed even if the primary lesion is benign in up to 70% of cases.
  • We report a 16 days old baby girl presented with a large, type 111 sacrococygeal teratoma.
  • The teratoma was disected from the surrounding structures and excised en bloc with the coccyx.
  • [MeSH-major] Soft Tissue Neoplasms / pathology. Soft Tissue Neoplasms / surgery. Teratoma / pathology. Teratoma / surgery

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  • (PMID = 20941978.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Romania
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9. Saba L, Guerriero S, Sulcis R, Virgilio B, Melis G, Mallarini G: Mature and immature ovarian teratomas: CT, US and MR imaging characteristics. Eur J Radiol; 2009 Dec;72(3):454-63
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  • [Title] Mature and immature ovarian teratomas: CT, US and MR imaging characteristics.
  • Ovarian teratomas (OTs) are the most common germ cell neoplasm.
  • They include mature cystic teratomas, monodermal teratomas (neural tumors, struma ovarii, carcinoid tumors) and immature teratomas.
  • Teratomas are the most common benign ovarian neoplasms in women less than 45 years old.
  • The purpose of this paper is to review the most common types of teratomas and to describe CT, US and MR imaging features of the various types of mature and immature OTs.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis. Tomography, X-Ray Computed / methods. Ultrasonography / methods

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  • (PMID = 18804932.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Number-of-references] 93
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10. Sharif K, Alton H, Clarke J, Desai M, Morland B, Parikh D: Paediatric thoracic tumours presenting as empyema. Pediatr Surg Int; 2006 Dec;22(12):1009-14
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  • Pre-operative CT scan with IV contrast in four children correctly identified underlying intra-thoracic tumour (two benign teratoma, two PNET).
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Female. Humans. Infant. Male. Punctures. Retrospective Studies. Teratoma / complications. Teratoma / diagnosis. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 17039385.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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11. Cebesoy FB, Baskonus I, Mete A, Kutlar I, Aybasti N: Benign ovarian dermoid cyst complicated with rectal fistula formation: an unusual case. Arch Gynecol Obstet; 2009 Feb;279(2):179-81
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  • [Title] Benign ovarian dermoid cyst complicated with rectal fistula formation: an unusual case.
  • BACKGROUND: Fistulation in benign cystic teratomas has not been commonly reported in the literature.
  • We present a case of a benign ovarian dermoid cyst complicated with a recto-ovarian fistula.
  • Gynecological examination and ultrasonography revealed a 10-cm heterogeneous cystic mass in the left ovary.
  • The pathological evaluation suggested benign ovarian dermoid tumor penetrating the rectum wall.

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  • (PMID = 18449552.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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12. Min KJ, Jee BC, Lee HS, Kim YB: Intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary: a case report. Pathol Res Pract; 2006;202(7):531-5
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  • [Title] Intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary: a case report.
  • Gastrointestinal adenocarcinoma arising in mature cystic teratomas of the ovary is extremely rare.
  • We report a case of well-differentiated intestinal adenocarcinoma arising in a mature cystic teratoma of the ovary in a 77-year-old woman, presenting as acute abdomen with ovarian torsion.
  • [MeSH-major] Adenocarcinoma / pathology. Intestinal Neoplasms / pathology. Neoplasms, Multiple Primary. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16713128.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 0 / MUC2 protein, human; 0 / Mucin-2; 0 / Mucins; 68238-35-7 / Keratins
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13. Kunieda E, Hara H, Morikawa Y, Hirobe S, Kamagata S, Kubo A: Accumulation of gallium-67 within mature and immature teratoma in pediatric patients: investigation for the uptake mechanism. Ann Nucl Med; 2008 Apr;22(3):207-13
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Accumulation of gallium-67 within mature and immature teratoma in pediatric patients: investigation for the uptake mechanism.
  • OBJECTIVE: We encountered cases of mature and immature teratoma with positive uptake of (67)Ga.
  • The objective of this study is to investigate the mechanism of (67)Ga accumulation within mature and immature teratomas by comparing the findings of gallium scan, computed tomography (CT), and autoradiography of surgical specimens with the pathological findings.
  • METHODS: The subjects comprised 14 children who underwent surgical resection for intra-abdominal mature and immature teratomas, which were histologically proved to be of the mature and immature subtype.
  • The origins of the mature teratomas consisted of seven ovaries including one bilateral case, two retroperitoneal, and two sacrococcygeal regions.
  • The origins of the immature teratomas were retroperitoneum in two cases, an ovary and a sacrococcygeal region.
  • All had typical CT findings of teratoma, including calcifications, fat components, cystic areas, and solid parts. (67)Ga accumulation in the four mature teratomas appeared discretely strong, and was considered to correspond with intralesional calcifications.
  • However, in the remaining one immature teratoma, the gallium distribution was diffuse within the tumor.
  • The comparison between radiography and autoradiography of the resected mature teratomas confirmed the correlation between the intralesional calcifications and areas of (67)Ga accumulation.
  • CONCLUSIONS: A high-uptake ratio of (67)Ga in benign teratoma was indicated.
  • [MeSH-major] Calcinosis / radionuclide imaging. Gallium Radioisotopes / pharmacokinetics. Ovarian Neoplasms / radionuclide imaging. Retroperitoneal Neoplasms / radionuclide imaging. Teratoma / radionuclide imaging

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  • (PMID = 18498036.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Gallium Radioisotopes; 0 / Radiopharmaceuticals
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4. Ding DC, Chen SS: Conservative laparoscopic management of ovarian teratoma torsion in a young woman. J Chin Med Assoc; 2005 Jan;68(1):37-9
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  • [Title] Conservative laparoscopic management of ovarian teratoma torsion in a young woman.
  • Benign cystic tumors, specifically dermoid or mucinous cysts, are the most frequent causes of ovarian torsion.
  • In this report, we present a case of adnexal torsion due to cystic teratoma.
  • The pathology revealed cystic teratoma of the ovary.
  • [MeSH-major] Ovarian Neoplasms / surgery. Teratoma / surgery
  • [MeSH-minor] Abdomen / pathology. Abdomen / surgery. Abdomen, Acute / etiology. Adult. Emergencies. Female. Humans. Laparoscopy. Torsion Abnormality / surgery. Treatment Outcome

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  • (PMID = 15742862.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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15. Lopes MA, Pereira CM, da Cruz Perez DE, Vargas PA, de Almeida OP: Benign teratoma of the buccal mucosa in a 9-year-old girl: report of case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2005 Nov;100(5):598-602
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  • [Title] Benign teratoma of the buccal mucosa in a 9-year-old girl: report of case and review of the literature.
  • Teratomas are embryonal tumors composed of tissues from all 3 germinal layers with variable levels of maturity.
  • Teratomas are rare in the head and neck region, representing less than 5% of all cases.
  • Oral teratomas are extremely uncommon, and we found only 21 cases published in the English-language literature.
  • We describe an unusual case of oral teratoma on the right buccal mucosa of a 9-year-old girl.
  • [MeSH-major] Mouth Mucosa / pathology. Mouth Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16243246.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 24
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16. Lao M, Koike J, Chauhan S, Schiano M, Plata M: Struma Ovarii with a focus of follicular variant of papillary thyroid cancer: a case report. W V Med J; 2008 Jul-Aug;104(4):12-4
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  • BACKGROUND: Struma Ovarii is a mature ovarian teratoma that consists mainly of thyroid tissue.
  • Mature cystic teratomas may contain small amounts of thyroid tissue.


17. Nishihara E, Miyauchi A, Hirokawa M, Kudo T, Ohye H, Ito M, Kubota S, Fukata S, Amino N, Kuma K: Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature. Endocrine; 2006 Oct;30(2):231-6
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  • [Title] Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature.
  • Benign thyroid teratomas are rare in adolescents and adults.
  • We report on three cases of benign thyroid teratomas that presented as painful tumors in the neck after puberty.
  • The tumor adjacent to the thyroid in each case showed rapid enlargement with predominant cystic lesions within several months.
  • The accumulation of cystic fluid in each case was refractory to drainage treatment or percutaneous ethanol injection therapy.
  • The patients subsequently underwent resection of the tumor, and microscopic examination revealed various types of tissue including pancreas, adipose, cartilage, muscle, and skin, and the cystic wall was lined by gastric, intestinal, respiratory, and stratified squamous epithelium.
  • Surgical resection was curative, and subsequent histologic examination revealed mature benign teratomas of the thyroid.
  • The main characteristic of our cases presented the painful tumors due to the enlarged cystic formation lined by a variety of different types of epithelium, which agreed with previous cases of benign thyroid teratomas in adolescents and adults.
  • [MeSH-major] Pain / diagnosis. Teratoma / diagnosis. Thyroid Neoplasms / diagnosis. Thyroid Nodule / diagnosis

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  • (PMID = 17322585.001).
  • [ISSN] 1355-008X
  • [Journal-full-title] Endocrine
  • [ISO-abbreviation] Endocrine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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18. Sahraoui W, Hajji S, Essefi A, Haouas N, Hmissa S, Bibi M, Khairi H: [Ovary teratoma. Report of 91 cases]. Tunis Med; 2006 Jun;84(6):349-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Ovary teratoma. Report of 91 cases].
  • OBJECTIVE: To analyse the clinical and anatomic aspects of cystic teratomas of the ovary, caracteristics of patients having cystic teratomas and the management trends at our institution.
  • STUDY DESIGN: Retrospective study of 91 cases of cystic teratomas of the ovary diagnosed and treated at Farhat -Hached Hospital (Sousse) between 1 january 1995 and 30 june 2003.
  • RESULTS: Cystic teratomas constituted 12.13% of all ovarian tumors diagnosed and treated at our institution during the study period.
  • The rate of bilateral cystic teratomas of the ovary was 14.3%.
  • 19.8% of cystic teratomas has occurred in pregnancy.
  • Histopathological evaluation has detected 96.7% cases of mature teratomas, and 3.3% cases of immature teratomas.
  • CONCLUSION: Cystic tertomas are the most common ovarian neoplasms, that occurs most commonly during the reproductive years.
  • The operative laparoscopy is the most common modality of treatment of mature cystic teratomas.
  • Immature teratomas must be treated by laparotomy associated if necessary to chimiothrapiy.
  • [MeSH-major] Ovarian Neoplasms. Teratoma

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  • (PMID = 17042207.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Tunisia
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19. Lagger S, Meunier D, Mikula M, Brunmeir R, Schlederer M, Artaker M, Pusch O, Egger G, Hagelkruys A, Mikulits W, Weitzer G, Muellner EW, Susani M, Kenner L, Seiser C: Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans. EMBO J; 2010 Dec 01;29(23):3992-4007
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  • [Title] Crucial function of histone deacetylase 1 for differentiation of teratomas in mice and humans.
  • To explore the role of HDAC1 in tumourigenesis and tumour proliferation, we established an experimental teratoma model using wild-type and HDAC1-deficient embryonic stem cells.
  • HDAC1-deficient teratomas showed no significant difference in size compared with wild-type teratomas.
  • Increased levels of the transcriptional regulator SNAIL1 are crucial for enhanced proliferation and reduced differentiation of HDAC1-deficient teratoma.
  • Importantly, the analysis of human teratomas revealed a similar link between loss of HDAC1 and enhanced tumour malignancy.
  • These findings reveal a novel role for HDAC1 in the control of tumour proliferation and identify HDAC1 as potential marker for benign teratomas.
  • [MeSH-major] Embryonic Stem Cells / metabolism. Gene Expression Regulation, Neoplastic. Histone Deacetylase 1 / genetics. Teratoma / enzymology

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  • [CommentIn] EMBO J. 2010 Dec 1;29(23):3893-5 [21124297.001]
  • [ErratumIn] EMBO J. 2011 Apr 20;30(8):1671
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  • (PMID = 20967026.001).
  • [ISSN] 1460-2075
  • [Journal-full-title] The EMBO journal
  • [ISO-abbreviation] EMBO J.
  • [Language] eng
  • [Grant] Austria / Austrian Science Fund FWF / / P 18659; Austria / Austrian Science Fund FWF / / V 102
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cadherins; 0 / Octamer Transcription Factor-3; 0 / SNAI1 protein, human; 0 / Snai1 protein, mouse; 0 / Snail Family Transcription Factors; 0 / Transcription Factors; EC 3.5.1.98 / Histone Deacetylase 1
  • [Other-IDs] NLM/ PMC3020644
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20. Steffensen TS, Quintero RA, Kontopoulos EV, Gilbert-Barness E: Massive pericardial effusion treated with in utero pericardioamniotic shunt in a fetus with intrapericardial teratoma. Fetal Pediatr Pathol; 2009;28(5):216-31
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  • [Title] Massive pericardial effusion treated with in utero pericardioamniotic shunt in a fetus with intrapericardial teratoma.
  • Teratoma is the leading neoplasm diagnosed in neonates and infants.
  • Although over 99% of teratomas found in the fetus and newborn are histologically benign, those tumors may cause death if vital structures are involved or if the airway is compromised.
  • We review the literature on antenatal intrapericardial teratomas and report a case of intrapericardial teratoma, with massive pericardial effusion and fetal hydrops, diagnosed on antenatal ultrasound at 21 weeks of gestation.
  • [MeSH-major] Fetal Heart. Pericardial Effusion / surgery. Prenatal Diagnosis. Teratoma. Ultrasonography, Prenatal


21. Ben Hassine L, Sahli H, Douira W, Louati H, Bellagha I: [Mature presacral teratoma of adults]. Tunis Med; 2010 Jan;88(1):64-6
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  • [Title] [Mature presacral teratoma of adults].

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  • (PMID = 20415222.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
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22. Dalloul M, Sherer DM, Gorelick C, Serur E, Zinn H, Sanmugarajah J, Zigalo A, Abulafia O: Transient bilateral ovarian enlargement associated with large retroperitoneal lymphoma. Ultrasound Obstet Gynecol; 2007 Feb;29(2):236-8
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  • Bilateral ovarian enlargement may reflect benign or malignant processes of the ovary.
  • Benign causes of ovarian enlargement include luteomas, tumors such as mature cystic teratomas, fibrothecomas, cystadenomas and rare conditions including capillary hemangioma and massive edema of the ovaries.

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  • [Copyright] Copyright 2007 ISUOG. Published by John Wiley & Sons, Ltd.
  • (PMID = 17252529.001).
  • [ISSN] 0960-7692
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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23. Tuma J: [CME ultrasound diagnosis 30. Mature teratoma]. Praxis (Bern 1994); 2009 Sep 23;98(19):1107-9
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  • [Title] [CME ultrasound diagnosis 30. Mature teratoma].
  • [Transliterated title] CME-Sonographie 30/Auflösung. Reifes Teratom.
  • [MeSH-major] Ovarian Cysts / radiography. Ovarian Neoplasms / radiography. Teratoma / ultrasonography

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  • (PMID = 19774523.001).
  • [ISSN] 1661-8157
  • [Journal-full-title] Praxis
  • [ISO-abbreviation] Praxis (Bern 1994)
  • [Language] ger
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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24. Sánchez Andrés A, Valdés Diéguez E, Marco Macián A, Carrasco Moreno JI: [Immature ovarian tumour and dilated myocardiopathy]. An Pediatr (Barc); 2010 Dec;73(6):347-51
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  • [Transliterated title] Teratoma inmaduro de ovario y miocardiopatía dilatada.
  • The ultrasound examination showed a solid-cystic tumour above the left kidney.
  • The highly vascularised retroperitoneal tumour was resected without incident and confirmed the diagnosis of an immature Norris grade 2 teratoma grade.
  • Teratomas are rare tumours in childhood that generally have a benign course.
  • Dilated cardiomyopathy (DCM) secondary to, chromaffin cell tumours (phaeochromocytoma, neuroblastoma, ganglioneuroblastoma), leukaemia infiltrates, and treatment with anthracyclines have been described, but there is no case reported in the literature regarding a teratoma with dilated cardiomyopathy.
  • [MeSH-major] Cardiomyopathy, Dilated / complications. Ovarian Neoplasms / complications. Teratoma / complications

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  • [Copyright] Copyright © 2010 Asociación Española de Pediatría. Published by Elsevier Espana. All rights reserved.
  • (PMID = 20863775.001).
  • [ISSN] 1695-9531
  • [Journal-full-title] Anales de pediatría (Barcelona, Spain : 2003)
  • [ISO-abbreviation] An Pediatr (Barc)
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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25. Thamboo TP, Sim R, Tan SY, Yap WM: Primary retroperitoneal mucinous cystadenocarcinoma in a male patient. J Clin Pathol; 2006 Jun;59(6):655-7
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  • The 64-year-old man presented with a large retroperitoneal cystic tumour measuring 24 x 20 x 16 cm3, which was removed intact.
  • Areas ranging from a benign mucinous cyst to borderline mucinous tumour to mucinous cystadenocarcinoma were observed on microscopy.
  • Strong patchy staining for cytokeratins 7 and 20 and strong diffuse staining for MUC2 and MUC5AC core peptides, similar to staining patterns in ovarian mucinous tumours, were shown in the benign and atypical epithelium.
  • The theory of its origin from the mucinous metaplasia of peritoneal (mesothelial) inclusion cysts, rather than from ectopic ovarian tissue or ovarian teratomas, is supported by the occurrence of such a tumour in a male patient.

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  • (PMID = 16731606.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Mucins; 0 / Neoplasm Proteins; 68238-35-7 / Keratins
  • [Number-of-references] 15
  • [Other-IDs] NLM/ PMC1860402
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26. Charlier P, Huynh-Charlier I, Brun L, Devisme L, Catalano P: [A 1800-year-old mediastinal mature teratoma]. Ann Pathol; 2009 Feb;29(1):67-9
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  • [Title] [A 1800-year-old mediastinal mature teratoma].
  • [MeSH-major] Mediastinal Neoplasms / history. Teratoma / history

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  • (PMID = 19233101.001).
  • [ISSN] 0242-6498
  • [Journal-full-title] Annales de pathologie
  • [ISO-abbreviation] Ann Pathol
  • [Language] fre
  • [Publication-type] Historical Article; Letter
  • [Publication-country] France
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27. Güvenç BH, Etus V, Muezzinoglu B: Lumbar teratoma presenting intradural and extramedullary extension in a neonate. Spine J; 2006 Jan-Feb;6(1):90-3
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  • [Title] Lumbar teratoma presenting intradural and extramedullary extension in a neonate.
  • BACKGROUND CONTEXT: The association of teratomas and spinal malformations such as spina bifida, partial sacral agenesis, hemivertebrae, and diastematomyelia has been described in the literature.
  • PURPOSE: A case of lumbar teratoma with an intradural extension and extramedullary component and the clinical outcome following surgical treatment are reported.
  • STUDY DESIGN/SETTING: To our knowledge, among the reported teratoma cases with an intradural extension and extramedullary component, our case has a distinguishing feature regarding the involvement of the lumbar spine.
  • The mass contained an irregular, bone-like, hard and mobile material accompanying cystic components.
  • The pathological examination showed a benign teratoma containing mature cartilage, muscle, adipose tissue, and glandular tissue.
  • CONCLUSION: Accompanying a spinal dysraphic state, the mature teratoma in our case may support the idea of a tumor actually arising from a dysraphism and growing outward to produce the mass.
  • [MeSH-major] Lumbar Vertebrae. Neoplasm Invasiveness / pathology. Spinal Cord Neoplasms / diagnosis. Spinal Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 16413454.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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28. Souftas V, Polychronidis A, Giatromanolaki A, Perente S, Simopoulos C: Dermoid cyst in the hepatoduodenal ligament: report of a case. Surg Today; 2008;38(10):959-61
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  • We report an unusual case of a mature cystic teratoma, or dermoid cyst, in the hepatoduodenal ligament of a young woman.
  • Mature cystic teratomas are rarely found in extragonadal sites, especially the hepatoduodenal ligament.
  • Patients who undergo complete resection of a mature cystic teratoma normally have an excellent prognosis.

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  • (PMID = 18820876.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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29. Meuris B, Gewillig M, Meyns B: Extreme levels of alpha-fetoprotein in a newborn with a benign intrapericardial teratoma. Cardiol Young; 2006 Feb;16(1):76-7
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  • [Title] Extreme levels of alpha-fetoprotein in a newborn with a benign intrapericardial teratoma.
  • We report a neonate presenting with an intrapericardial benign teratoma and an exceptionally high level of alpha-fetoprotein.
  • Such severe elevation of alpha-fetoprotein in a neonate with a teratoma is usually associated with the presence of immature or malignant elements, compromising the prognosis.
  • The tumour in our patient, however, proved to be completely benign.
  • We discuss recent findings with regard to normal levels of alpha-fetoprotein levels in preterm infants, and in children with neonatal teratomas.
  • [MeSH-major] Biomarkers, Tumor / blood. Heart Neoplasms / blood. Pericardium. Teratoma / blood. alpha-Fetoproteins / metabolism

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  • (PMID = 16454881.001).
  • [ISSN] 1047-9511
  • [Journal-full-title] Cardiology in the young
  • [ISO-abbreviation] Cardiol Young
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / alpha-Fetoproteins
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30. Kitada M, Ozawa K, Sato K, Matsuda Y, Hayashi S, Sasajima T: Resection of a mediastinal mature teratoma diagnosed owing to sudden chest pain with elevated preoperative serum CA19-9. Gen Thorac Cardiovasc Surg; 2010 Jun;58(6):298-301
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  • [Title] Resection of a mediastinal mature teratoma diagnosed owing to sudden chest pain with elevated preoperative serum CA19-9.
  • Mediastinal teratomas are typically benign and asymptomatic, but they undergo sudden enlargement or rupture into neighboring organs in some patients owing to intratumoral hemorrhage, leading to serious complications.
  • We report the case of a mediastinal mature teratoma that was discovered because of the sudden onset of chest pain accompanied by elevated preoperative serum CA19-9 levels.
  • The tumor comprised soft tissue, fluid, and cystic components.
  • The histological diagnosis was mature teratoma with peritumoral bleeding.
  • [MeSH-major] CA-19-9 Antigen / blood. Chest Pain / etiology. Mediastinal Neoplasms / surgery. Teratoma / surgery. Thoracic Surgical Procedures

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  • [Cites] Jpn J Thorac Cardiovasc Surg. 2006 Mar;54(3):117-9 [16613230.001]
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  • (PMID = 20549462.001).
  • [ISSN] 1863-6713
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / CA-19-9 Antigen
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31. Yazici B, Erdoğmuş B: Floating ball appearance in ovarian cystic teratoma. Diagn Interv Radiol; 2006 Sep;12(3):136-8
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  • [Title] Floating ball appearance in ovarian cystic teratoma.
  • The presence of floating fat balls or globules in an ovarian cystic teratoma is an unusual finding.
  • Herein, we present ultrasonographic and tomographic findings of a rarely reported case of cystic teratoma with a floating fat ball.
  • [MeSH-major] Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16972218.001).
  • [ISSN] 1305-3825
  • [Journal-full-title] Diagnostic and interventional radiology (Ankara, Turkey)
  • [ISO-abbreviation] Diagn Interv Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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32. De Backer A, Madern GC, Oosterhuis JW, Hakvoort-Cammel FG, Hazebroek FW: Ovarian germ cell tumors in children: a clinical study of 66 patients. Pediatr Blood Cancer; 2006 Apr;46(4):459-64
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  • PROCEDURE: The records of 66 patients (median age 9 years) with histologically proven ovarian germ cell tumor (either benign or malignant), treated over a 44-year-span, were reviewed.
  • Histologically, teratomas were found most frequently (mature: 45, immature: 9), followed by mixed tumors (n = 7), yolk sac tumors (n = 3), dysgerminoma (n = 2), gonadoblastoma (n = 2), and embryonal carcinoma (n = 1).

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  • (PMID = 16206211.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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33. Koomalsingh KJ, Fazylov R, Chorost MI, Horovitz J: Cystic teratoma of the pancreas: presentation, evaluation and management. JOP; 2006;7(6):643-6
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  • [Title] Cystic teratoma of the pancreas: presentation, evaluation and management.
  • CONTEXT: Congenital cystic lesions of the pancreas are rare findings.
  • CASE REPORT: A 52-year-old male with a symptomatic, 3-cm cystic-type mass in the pancreas.
  • [MeSH-major] Pancreatic Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 17095845.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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34. Dhingra KK, Setia N, Khurana N: A rare case of congenital nasopharyngeal teratoma presenting with respiratory distress. Indian J Otolaryngol Head Neck Surg; 2010 Sep;62(3):329-31
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  • [Title] A rare case of congenital nasopharyngeal teratoma presenting with respiratory distress.
  • Teratomas of the head and neck are rare, benign neoplasms, usually presenting in the neonatal period and are often malignant with regard to their location.
  • Teratomas occur with a frequency of one in 4,000 live births with head and neck teratomas accounting for <5% of the total.
  • Extensive literature search has shown that there are only two cases congenital nasopharyngeal teratoma reported in India, and we report the third such case.

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  • [Cites] J Pediatr Surg. 1987 Feb;22(2):179-81 [3820022.001]
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  • (PMID = 23120736.001).
  • [ISSN] 2231-3796
  • [Journal-full-title] Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India
  • [ISO-abbreviation] Indian J Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3450234
  • [Keywords] NOTNLM ; Congenital / Nasopharyngeal / Teratoma
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35. Zwiesler D, Lewis SR, Choo YC, Martens MG: A case report of an ovarian lipoma. South Med J; 2008 Feb;101(2):205-7
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  • This is a case report of a lipoma of an ovary not associated with a teratoma or an hyperandrogenic state.
  • Microscopic examination demonstrated a pattern of proliferation of benign adipose tissue with focal areas of fibrovascular septae and no other tissue of different origin.
  • The cases reported were associated with teratomas, lipid cell tumors, and lipoleiomyomas.

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  • (PMID = 18364627.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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36. Murdock J, Abbas MA: Laparoscopic abdomino-paracoccygeal resection of anorectal cystic teratoma. JSLS; 2010 Oct-Dec;14(4):583-6
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  • [Title] Laparoscopic abdomino-paracoccygeal resection of anorectal cystic teratoma.
  • Sacrococcygeal teratoma rarely presents in adulthood (reported incidence of 1:87 000).
  • Adult anorectal teratoma is a rare variant of sacrococcygeal teratoma.
  • We present in this article the case of a young woman with a large cystic anorectal teratoma treated successfully with a combined laparoscopic abdomino-paracoccygeal resection.

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  • (PMID = 21605528.001).
  • [ISSN] 1086-8089
  • [Journal-full-title] JSLS : Journal of the Society of Laparoendoscopic Surgeons
  • [ISO-abbreviation] JSLS
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3083055
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37. Ulger Z, Egemen A, Karapinar B, Veral A, Apaydin F: A very rare cause of recurrent apnea: congenital nasopharyngeal teratoma. Turk J Pediatr; 2005 Jul-Sep;47(3):266-9
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  • [Title] A very rare cause of recurrent apnea: congenital nasopharyngeal teratoma.
  • The pathological evaluation of the excised mass revealed benign teratoma.
  • [MeSH-major] Apnea / etiology. Nasopharyngeal Neoplasms / complications. Respiratory Distress Syndrome, Adult / etiology. Teratoma / complications

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  • (PMID = 16250313.001).
  • [ISSN] 0041-4301
  • [Journal-full-title] The Turkish journal of pediatrics
  • [ISO-abbreviation] Turk. J. Pediatr.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
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38. Li F, Munireddy S, Jiang L, Cheng N, Mao H, Pawlik TM: Infected primary retroperitoneal teratoma presenting as a subhepatic abscess in a postpartum woman. Am J Surg; 2010 Feb;199(2):e27-8
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  • [Title] Infected primary retroperitoneal teratoma presenting as a subhepatic abscess in a postpartum woman.
  • It is highly unusual for a 20-cm retroperitoneal teratoma to present as a subhepatic abscess with septic shock in a postpartum woman.
  • We present a case of a multilocular cystic teratoma densely adherent to adjacent viscera and vessels.
  • [MeSH-major] Abdominal Abscess / etiology. Puerperal Disorders / etiology. Retroperitoneal Neoplasms / pathology. Teratoma / pathology

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20113696.001).
  • [ISSN] 1879-1883
  • [Journal-full-title] American journal of surgery
  • [ISO-abbreviation] Am. J. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Garrido Abad P, Herranz Fernández LM, Jiménez Gálvez M, Suárez Fonseca C, Sántos Arrontes D, Nieto Llanos S, Fernández Arjona M: [Mature cystic teratoma of the testis (dermoid cyst). Case report and literature review]. Arch Esp Urol; 2009 Nov;62(9):747-51
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  • [Title] [Mature cystic teratoma of the testis (dermoid cyst). Case report and literature review].
  • [Transliterated title] Teratoma quístico maduro testicular (quiste dermoide). Aportación de un caso y revisión de la literatura.
  • SUMMARY OBJECTIVES: Case report of a mature cystic teratoma (dermoid cyst), pseudopilomatrixoma like variant.
  • METHOD: 53-year old patient with a left testicular mass, diagnosed as mature cystic teratoma of the testis(dermoid cyst), the pilomatrixoma-like variant, after radical orchiectomy.
  • RESULTS: Testicular teratoma is a tumour composed of cells derived from the three embryonic layers (ectoderm, endoderm and mesoderm).
  • They are much less prevalent in adults,representing only 7% of all testicular germ cell tumours CONCLUSIONS: Prepubertal cases are invariably benign in nature, regardless of their histology.
  • Mature cystic teratoma (dermoid cyst) is the only exception to this rule, as no malignant degeneration of these types of tumours has been published.

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  • (PMID = 19955600.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
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40. Dalmau J, Bataller L: [Limbic encephalitis: the new cell membrane antigens and a proposal of clinical-immunological classification with therapeutic implications]. Neurologia; 2007 Oct;22(8):526-37
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  • Patients with antibodies against these receptors are young women with benign-appearing cystic tumors of the ovary (mature or immature teratomas), who develop a severe and characteristic encephalitis that we report in detail.

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  • (PMID = 18000762.001).
  • [ISSN] 0213-4853
  • [Journal-full-title] Neurología (Barcelona, Spain)
  • [ISO-abbreviation] Neurologia
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / Autoantibodies; 0 / Autoantigens; 0 / Membrane Proteins; 0 / Nerve Tissue Proteins; 0 / Potassium Channels; 0 / Receptors, N-Methyl-D-Aspartate
  • [Number-of-references] 55
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41. van der Steeg AF, Sleeboom C, Heij HA: [Internally situated sacrococcygeal teratomas, often invisible but not harmless]. Ned Tijdschr Geneeskd; 2009;153:A191
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  • [Title] [Internally situated sacrococcygeal teratomas, often invisible but not harmless].
  • A sacrococcygeal teratoma (SCT) may be completely concealed within the pelvis and therefore not be visible externally.
  • The first patient, a newborn girl, had an antenatally-diagnosed cystic mass in her pelvis, which was a benign SCT.
  • The second patient was a 2-year-old boy who after two incomplete resections of a benign intrapelvic SCT, developed a malignant SCT.
  • [MeSH-major] Spinal Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 19857297.001).
  • [ISSN] 1876-8784
  • [Journal-full-title] Nederlands tijdschrift voor geneeskunde
  • [ISO-abbreviation] Ned Tijdschr Geneeskd
  • [Language] dut
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Netherlands
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42. Kyritsis AP: Management of primary intracranial germ cell tumors. J Neurooncol; 2010 Jan;96(2):143-9
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  • They are divided into the following histologic types: germinoma, teratoma (mature, immature, malignant), choriocarcinoma, embryonal carcinoma, endodermal sinus tumor (yolk sac tumor), and mixed tumors.
  • Mature teratomas are treated with surgery.
  • The rest of germ cell tumors are managed with various combinations of surgery, chemotherapy, and radiotherapy depending on the tumor type.
  • Prognosis is best for germinomas and mature teratomas and worst for choriocarcinomas and embryonal carcinomas.
  • [MeSH-minor] Carcinoma, Embryonal / therapy. Germinoma / therapy. Humans. Magnetic Resonance Imaging / methods. Nerve Tissue Proteins / metabolism. Teratoma / therapy

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  • (PMID = 19588227.001).
  • [ISSN] 1573-7373
  • [Journal-full-title] Journal of neuro-oncology
  • [ISO-abbreviation] J. Neurooncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Nerve Tissue Proteins
  • [Number-of-references] 42
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43. Zarbo R, Scibilia G, Conoscenti G, Scollo P: Ovarian cystic teratoma with primary epithelial cell melanoma. Eur J Gynaecol Oncol; 2005;26(1):71-4
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  • [Title] Ovarian cystic teratoma with primary epithelial cell melanoma.
  • We report a rare case of malignant melanoma arising in a cystic teratoma of the ovary occurring in a 60-year-old woman who died in four months despite the combined treatment administrated (surgery and chemotherapy).
  • [MeSH-major] Melanoma / diagnosis. Neoplasms, Multiple Primary / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 15755005.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Italy
  • [Number-of-references] 41
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44. Yoshikata R, Yamamoto T, Kobayashi M, Ota H: Immunohistochemical characteristics of mature ovarian cystic teratomas in patients with postoperative recurrence. Int J Gynecol Pathol; 2006 Jan;25(1):95-100
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  • [Title] Immunohistochemical characteristics of mature ovarian cystic teratomas in patients with postoperative recurrence.
  • Because a mature teratoma could recur, we studied the clinical, pathological, and immunohistochemical characteristics of mature ovarian cystic teratomas of 121 patients who underwent surgeries between 1994 and 2002.
  • Recurrence was defined as cases that required secondary surgeries for mature ovarian cystic teratomas.
  • Our result showed that maturation of teratomas reduced the number of neurons and increased glia.
  • The presence of tridermal components and a high synaptophysin/glial fibrillary acidic protein (SP/GFAP) ratio suggested that recurrent ovarian teratomas were capable of both neuronal and glial differentiations.
  • [MeSH-major] Neoplasm Recurrence, Local. Ovarian Neoplasms / chemistry. Teratoma / chemistry

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  • (PMID = 16306792.001).
  • [ISSN] 0277-1691
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Intermediate Filament Proteins; 0 / NES protein, human; 0 / Nerve Tissue Proteins; 0 / Nestin; 0 / Synaptophysin
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45. Fan SQ, Liang QC, Jiang Y: Thyroid teratoma in an 11-month-old infant. Int J Surg; 2008 Dec;6(6):462-4
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  • [Title] Thyroid teratoma in an 11-month-old infant.
  • We report a case of congenital benign thyroid teratoma in an 11-month-old male infant who was found to have right thyroid gland mass since birth.
  • Histologically, tumor had mature derivatives of the three primordial germ layers with a variety of benign and well-differentiated elements.
  • In summary, benign teratoma of thyroid gland in an 11-month-old infant was morphologically and immunophenotypically identified.
  • [MeSH-major] Teratoma / pathology. Thyroid Neoplasms / pathology

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  • (PMID = 19059145.001).
  • [ISSN] 1743-9159
  • [Journal-full-title] International journal of surgery (London, England)
  • [ISO-abbreviation] Int J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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46. Kauffman RM, Netterville JL, Burkey BB: Transoral excision of the submandibular gland: techniques and results of nine cases. Laryngoscope; 2009 Mar;119(3):502-7
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  • Three patients presented with other benign cystic lesions consistent with a ranula, an infected mucocele, and a cystic teratoma.
  • Although the surgical anatomy is somewhat novel, the transoral approach has been used effectively and without complication in removing benign submandibular gland pathology in our series.

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  • (PMID = 19235741.001).
  • [ISSN] 1531-4995
  • [Journal-full-title] The Laryngoscope
  • [ISO-abbreviation] Laryngoscope
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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47. Antón L, Pérez-Etchepare E, Soriano D, Gómez M, Barrientos G, Tracchia R: [Testicular tumors: wide spectrum in our short casuistics]. Cir Pediatr; 2010 Oct;23(4):222-4
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  • We report seven cases, three germ cell tumors: a Yolk sac tumor in a child of 18 months and two mature teratomas in children between 2 and 11 years presenting as a painless testicular mass without other symptoms.
  • Many are benign and can be treated with preservation of the testis.

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  • (PMID = 21520554.001).
  • [ISSN] 0214-1221
  • [Journal-full-title] Cirugía pediátrica : organo oficial de la Sociedad Española de Cirugía Pediátrica
  • [ISO-abbreviation] Cir Pediatr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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48. Taskinen S, Fagerholm R, Aronniemi J, Rintala R, Taskinen M: Testicular tumors in children and adolescents. J Pediatr Urol; 2008 Apr;4(2):134-7
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  • In 23 (68%) the tumor was benign: benign teratoma (16), Leydig-cell tumor (2), epidermoid cyst (2), Sertoli-cell tumor (1), cystic dysplasia (1), intratesticular focal fibrosis (1).
  • Twenty out of the 26 (77%) prepubertal boys had a benign tumor in contrast to only three of the eight (38%) adolescent males (P=0.079).
  • Two patients with benign teratoma had a recurrence due to incomplete primary resection.
  • In one patient who underwent orchiectomy for benign teratoma, two metachronous teratomas were detected in the contralateral testis 6 years after primary surgery.
  • CONCLUSIONS: In children, most testicular tumors are benign, especially before puberty.
  • The possibility of metachronous bilateral tumors should be considered in the follow up of testicular teratomas.
  • [MeSH-major] Teratoma / epidemiology. Teratoma / surgery. Testicular Neoplasms / epidemiology. Testicular Neoplasms / surgery

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  • (PMID = 18631909.001).
  • [ISSN] 1873-4898
  • [Journal-full-title] Journal of pediatric urology
  • [ISO-abbreviation] J Pediatr Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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49. Bal J, Gabryś MS, Jałocha I: [The role of selected molecular pathways in the pathogenesis of ovarian teratomas]. Postepy Hig Med Dosw (Online); 2009 May 20;63:242-9
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  • [Title] [The role of selected molecular pathways in the pathogenesis of ovarian teratomas].
  • From the research point of view--ovarian teratomas, especially mature ones, are an interesting group of germ-cell tumors of the ovary.
  • Mature ovarian teratomas are benign germ-cell tumors, but in rare cases, especially when they contain solid elements, peritoneal implants may be present which can stimulate malignant processes.
  • Dermoid cysts, a subtype of ovarian teratomas, arise from totipotential germ cells and may therefore contain elements of all three germ layers, although ectodermal structures usually predominate.
  • Radical surgical treatment is not necessity for this type of tumor because conservative surgery usually brings full recovery.However, they make perfect material for gaining interesting information regarding oocyte maturation and such critical cellular functions as proliferation, migration, differentiation, and apoptosis.There are still no unequivocal conclusions related to the role of mutation in genes which influence the mechanisms involved in control of the cell cycle and which may play important roles in the development of ovarian teratomas.

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  • (PMID = 19502685.001).
  • [ISSN] 1732-2693
  • [Journal-full-title] Postepy higieny i medycyny doswiadczalnej (Online)
  • [ISO-abbreviation] Postepy Hig Med Dosw (Online)
  • [Language] POL
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / CCNC protein, human; 0 / Cyclin C; 0 / Cyclins; EC 2.7.11.1 / Oncogene Protein v-akt
  • [Number-of-references] 42
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50. Sheikh MA, Akhtar J, Batool T, Naqvi R, Taqvi R, Jalil S, Soomro A, Ahmed S, Mirza F: A study of ovarian lesions in pre-menarche girls. J Coll Physicians Surg Pak; 2007 Mar;17(3):162-5
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  • Six patients had non-tumorous cysts, 3 had benign tumors and 9 were with malignant lesions.
  • There were 2 patients with benign teratoma and one with dermoid cyst.
  • Four patients had malignant teratoma, 4 dysgerminoma and one yolk sac tumor.
  • Benign (tumorous and non-tumorous) and malignant lesions occurred with equal frequency in pre-menarche girls in this study.

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  • (PMID = 17374303.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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51. Chaudhary A, Misra S, Wakhlu A, Tandon RK, Wakhlu AK: Retroperitoneal teratomas in children. Indian J Pediatr; 2006 Mar;73(3):221-3
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  • [Title] Retroperitoneal teratomas in children.
  • OBJECTIVE: This paper aims to highlight the clinical features, investigations and treatment of retroperitoneal teratomas condition.
  • METHODS: 12 patients (8 females and 4 males, age range-2 months to 14 yrs) of retroperitoneal teratoma admitted to the department of Pediatric Surgery, King George Medical University, Lucknow between 1980 and 2004 were studied.
  • In one child with a massive cystic tumor with bilateral involvement, the tumor was marsupialised in the first stage and excised subsequently.
  • CONCLUSIONS: Retroperitoneal teratomas are uncommon lesions in children mostly arising in close relation to the kidneys.
  • The majority are benign but complete excision is necessary for cure.
  • [MeSH-major] Retroperitoneal Neoplasms / surgery. Teratoma / surgery

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  • [Cites] Khirurgiia (Sofiia). 1990;43(4):1-5 [2097415.001]
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  • (PMID = 16567916.001).
  • [ISSN] 0973-7693
  • [Journal-full-title] Indian journal of pediatrics
  • [ISO-abbreviation] Indian J Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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52. Kohlhof JK, Driemel O, Müller-Richter U: [Congenital mature teratoma of the right orbit]. Klin Monbl Augenheilkd; 2007 Dec;224(12):935-8
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  • [Title] [Congenital mature teratoma of the right orbit].
  • [Transliterated title] Kongenitales reifes Teratom der rechten Orbita.
  • BACKGROUND: Teratomas are congenital embryonic tumours composed of a wide diversity of tissues derived from the three germinal layers (ectoderm, mesoderm, endoderm).
  • A congenital mature teratoma was diagnosed.
  • CONCLUSIONS: The case presented underlines the possible extent and impact of congenital mature teratomas.
  • [MeSH-major] Orbital Neoplasms / congenital. Teratoma / congenital

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  • (PMID = 18260058.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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53. Glanc P, Salem S, Farine D: Adnexal masses in the pregnant patient: a diagnostic and management challenge. Ultrasound Q; 2008 Dec;24(4):225-40
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  • Familiarity with the natural history and sonographic features of common adnexal lesions, such as simple cysts, hemorrhagic cysts, endometriomas, mature cystic teratomas, and ovarian conditions specific to pregnancy, may permit stratification of patients into management protocols.

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  • (PMID = 19060689.001).
  • [ISSN] 1536-0253
  • [Journal-full-title] Ultrasound quarterly
  • [ISO-abbreviation] Ultrasound Q
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 86
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54. Wu DH, McMurtrie DG, Hirsch SD, Johnston CM: Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report. J Reprod Med; 2008 Feb;53(2):141-4
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  • [Title] Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report.
  • BACKGROUND: Mature, benign cystic teratomas of the ovary are common in reproductive-age women, but they are very rarely associated with androgen production and subsequent development of hirsutism or virilization.
  • We describe a case of postmenopausal hirsutism and hyperandrogenism caused by a mature cystic teratoma as well as the 7 previously reported cases.
  • Pelvic ultrasound showed a complex cystic mass in the left ovary measuring 6.0 x 7.0 x 10 cm, and laboratory evaluations revealed progressively increasing testosterone levels.
  • The pathology department found 2 left, mature ovarian cystic teratomas containing a layer of Leydig cells.
  • CONCLUSION: Although rare, ovarian production of androgens resulting in hirsutism or virilization can occur with a hormonally active mature cystic teratoma.
  • [MeSH-major] Hyperandrogenism / etiology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18357809.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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55. Paramythiotis D, Papavramidis TS, Michalopoulos A, Papadopoulos VN, Apostolidis S, Televantou D, Hytiroglou P: Chronic constipation due to presacral teratoma in a 36-year-old woman: a case report. J Med Case Rep; 2010;4:23
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  • [Title] Chronic constipation due to presacral teratoma in a 36-year-old woman: a case report.
  • INTRODUCTION: Teratomas of the sacrococcygeal area are usually diagnosed in infancy and are rarely seen in adults.
  • CASE PRESENTATION: We report the case of a 36-year-old Greek woman experiencing chronic constipation due to a benign presacral teratoma.
  • A histologic examination revealed a mature cystic teratoma.
  • CONCLUSION: Sacrococcygeal teratomas are rare in adults.

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  • [Cites] Eur Radiol. 2002 Jun;12(6):1546-9 [12042966.001]
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  • (PMID = 20205878.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2827428
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56. Lai C, Zhang SZ, Yang HJ: [MRI diagnosis of benign sacrococcygeal teratomas of the infants]. Zhejiang Da Xue Xue Bao Yi Xue Ban; 2006 Jan;35(1):103-7
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  • [Title] [MRI diagnosis of benign sacrococcygeal teratomas of the infants].
  • OBJECTIVE: To investigate the value of MR imaging in the diagnosis of benign sacrococcygeal teratomas of the infants.
  • METHODS: MR imaging of benign sacrococcygeal teratomas in 6 cases proved by surgery and pathology was retrospectively reviewed.
  • RESULTS: There were 6 benign sacrococcygeal teratomas, which were heterogeneous masses and arose from the distal sacrococcygeal region in the pelvis.
  • The MR imaging appearances of the benign sacrococcygeal teratomas were characteristic, T1- and T2-weighted images demonstrated a large mass containing round, well-defined areas of varying signal intensity representing its cystic, solid, and sometimes fat, calcification within the lesions.
  • CONCLUSION: MR imaging provides definitive information of benign sacrococcygeal teratomas and clearly shows both extra-and intra-pelvic components, and even better anatomic details, which facilitates the surgical planning adequately.
  • [MeSH-major] Magnetic Resonance Imaging. Retroperitoneal Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 16470930.001).
  • [ISSN] 1008-9292
  • [Journal-full-title] Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
  • [ISO-abbreviation] Zhejiang Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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57. Güney M, Oral B, Demir F, Ozsoy M, Kapucuoğlu N: Mucinous adenocarcinoma arising from the gastrointestinal epithelium in benign cystic teratoma of the ovary--case report. Eur J Gynaecol Oncol; 2006;27(3):304-6
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  • [Title] Mucinous adenocarcinoma arising from the gastrointestinal epithelium in benign cystic teratoma of the ovary--case report.
  • Benign cystic teratoma of the ovary (BCTO) is the most common ovarian germ cell tumor occurring predominantly in early adulthood.
  • Most benign cystic teratomas with malignant transformations are squamous cell carcinomas with just 6.8% being adenocarcinomas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16800267.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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58. Islam S, Yamout SZ, Gosche JR: Management and outcomes of ovarian masses in children and adolescents. Am Surg; 2008 Nov;74(11):1062-5
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  • Eight masses were malignant (16%) with malignant teratoma, dysgerminoma, and germ cell tumors found.
  • Seventy-four per cent of the benign tumors were teratomas.
  • Most ovarian masses in childhood are benign.
  • Consideration for laparoscopic procedures should be given for the benign lesions.

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  • (PMID = 19062661.001).
  • [ISSN] 0003-1348
  • [Journal-full-title] The American surgeon
  • [ISO-abbreviation] Am Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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59. Rivkine E, Goasguen N, Chelbi E, Couvelard A, Vullierme MP, Vilgrain V, Hammel P, Sauvanet A: [Cystic teratoma of the pancreas]. Gastroenterol Clin Biol; 2007 Nov;31(11):1016-9
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  • [Title] [Cystic teratoma of the pancreas].
  • [Transliterated title] Tératome kystique du pancréas.
  • The preoperative diagnosis of cystic tumours of the pancreas can be difficult.
  • However, the latter can be misinterpreted in case of exceptional cystic tumours, other that cystadenomas.
  • We report here the case of a 45-year old woman who was operated on for a benign cystic mature teratoma with endocrine component and high concentrations in cyst fluid CEA and CA 72.4 which was evocative of a malignant mucinous cystadenoma.
  • [MeSH-major] Pancreatic Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 18166898.001).
  • [ISSN] 0399-8320
  • [Journal-full-title] Gastroentérologie clinique et biologique
  • [ISO-abbreviation] Gastroenterol. Clin. Biol.
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Antigens, Tumor-Associated, Carbohydrate; 0 / Biomarkers, Tumor; 0 / CA-72-4 antigen; 0 / Carcinoembryonic Antigen
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60. Woodward PJ, Sohaey R, Kennedy A, Koeller KK: From the archives of the AFIP: a comprehensive review of fetal tumors with pathologic correlation. Radiographics; 2005 Jan-Feb;25(1):215-42
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  • Teratomas are the dominant histologic type and constitute the majority of both extracranial and intracranial neoplasms.
  • Extracranial teratomas are most commonly located in the sacrococcygeal area, followed by the head and neck, chest, and retroperitoneum.
  • Fetuses with intracranial tumors have a poor prognosis regardless of histologic type.
  • It may be either solid or cystic and is more often located on the right side.
  • Other fetal neoplasms include soft-tissue tumors (both benign and malignant), leukemia, mesenchymal hamartoma of the kidney, and liver tumors (hemangioendothelioma, mesenchymal hamartoma, and hepatoblastoma).
  • [MeSH-minor] Brain Neoplasms / diagnosis. Female. Humans. Magnetic Resonance Imaging. Pregnancy. Teratoma / diagnosis. Ultrasonography, Prenatal

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  • (PMID = 15653597.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 82
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61. Altinbas SK, Yalvac S, Kandemir O, Altinbas NK, Karcaaltincaba D, Dede H, Demir OF: An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report. J Clin Ultrasound; 2010 Jul;38(6):325-7
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  • [Title] An unusual growth of ovarian cystic teratoma with multiple floating balls during pregnancy: a case report.
  • We report a case of ovarian cystic teratoma with an important growth during pregnancy and the sonographic appearance of intracystic multiple, mobile, polygonal structures called intracystic "fat balls."
  • Histopathologic diagnosis confirmed the mature cystic teratoma.
  • The presence of floating balls composed of keratin and fat is rarely seen but is pathognomonic of mature cystic teratomas.
  • Growth of a teratoma during pregnancy is a rare condition.
  • [MeSH-major] Adipose Tissue / ultrasonography. Ovarian Neoplasms / ultrasonography. Teratoma / ultrasonography

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  • (PMID = 20544870.001).
  • [ISSN] 1097-0096
  • [Journal-full-title] Journal of clinical ultrasound : JCU
  • [ISO-abbreviation] J Clin Ultrasound
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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62. Agrawal M, Uppin MS, Patibandla MR, Bhattacharjee S, Panigrahi MK, Saradhi V, Rani JY, Purohit AK, Challa S: Teratomas in central nervous system: a clinico-morphological study with review of literature. Neurol India; 2010 Nov-Dec;58(6):841-6
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  • [Title] Teratomas in central nervous system: a clinico-morphological study with review of literature.
  • BACKGROUND: Cranio-spinal axis teratomas are rare.
  • Histopathology is diagnostic; most of the lesions are benign.
  • AIMS: To study the demographic, clinico-morphological and follow-up data of central nervous system (CNS) teratomas.
  • MATERIALS AND METHODS: Cases diagnosed as mature or immature teratomas in the CNS over a 20-year period were included in the study.
  • RESULTS: A total of 14 tumors were diagnosed as teratomas.
  • Of these, 11 were mature cystic teratomas; and 1 case each, of teratoma with malignant transformation, terato-carcinoma and mixed germ cell tumor (immature teratoma with germinoma).
  • CONCLUSION: CNS teratomas are rare.
  • [MeSH-major] Central Nervous System Neoplasms / diagnosis. Central Nervous System Neoplasms / surgery. Teratoma / diagnosis. Teratoma / surgery

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  • (PMID = 21150046.001).
  • [ISSN] 0028-3886
  • [Journal-full-title] Neurology India
  • [ISO-abbreviation] Neurol India
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
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63. Kikuchi M, Mizutani K, Miwa K, Yokoi S, Nakano M, Ehara H, Deguchi T: Images in clinical urology. Floating balls appearance in testicular cystic teratoma. Urology; 2009 Jul;74(1):71-2
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  • [Title] Images in clinical urology. Floating balls appearance in testicular cystic teratoma.
  • Fourteen cases of a "floating balls" appearance on imaging studies in a mature ovarian cystic teratoma have been reported in published studies since 1991.
  • Because of self-examination, patients with testicular teratoma are usually referred to the hospital when the tumor is of a smaller size than that seen in patients with ovarian teratoma.
  • We report the first case of a floating balls appearance in a testicular teratoma.
  • [MeSH-major] Teratoma / pathology. Teratoma / ultrasonography. Testicular Neoplasms / pathology. Testicular Neoplasms / ultrasonography

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  • (PMID = 19362339.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Avci A, Eren S: Life-threatening giant mediastinal cystic teratoma in a 4-month-old male baby. Gen Thorac Cardiovasc Surg; 2009 Jul;57(7):389-91
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  • [Title] Life-threatening giant mediastinal cystic teratoma in a 4-month-old male baby.
  • Cystic teratomas of the mediastinum are rare and present with severe respiratory distress during childhood.
  • This report describes a 4-month-old male baby with a large anterior mediastinal teratoma presenting with severe respiratory distress.
  • The cystic teratoma was large enough to cause pectus carinatum.
  • Surgical excision is indicated for a malignant or benign well-demarcated mass in any part of the mediastinum.
  • Surgical excision is the best means of diagnosing and treating a benign teratoma.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Teratoma / surgery

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  • [Cites] J Thorac Cardiovasc Surg. 1983 Nov;86(5):727-31 [6632945.001]
  • [Cites] J Pediatr Surg. 1993 Sep;28(9):1161-4 [7508501.001]
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  • (PMID = 19597932.001).
  • [ISSN] 1863-6705
  • [Journal-full-title] General thoracic and cardiovascular surgery
  • [ISO-abbreviation] Gen Thorac Cardiovasc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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65. Luo CC, Huang CS, Chu SM, Chao HC, Yang CP, Hsueh C: Retroperitoneal teratomas in infancy and childhood. Pediatr Surg Int; 2005 Jul;21(7):536-40
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  • [Title] Retroperitoneal teratomas in infancy and childhood.
  • Retroperitoneal teratoma poses a significant problem in the differential diagnosis of Wilms' tumor, neuroblastoma, and other intraabdominal tumors.
  • In an attempt to establish the best diagnostic and treatment modality, we reviewed our experience with retroperitoneal teratomas at a single institution in a 5-year period.
  • Between January 1998 and December 2002, retroperitoneal teratomas were identified in 10 patients, seven females and three males, ranging from age 4 days to 12 years, with seven patients under the age of 1 year.
  • Total excision was performed in nine patients; another patient with grade III immature teratoma received postoperative chemotherapy besides excision.
  • One patient with grade III immature teratoma who did not receive postoperative chemotherapy had a local recurrence 6 months later and was treated by repeated surgical excision and postoperative chemotherapy.
  • Retroperitoneal teratomas were usually noted in patients under the age of 1 year.
  • Though large, they are mostly benign lesions with no apparent connection to the retroperitoneal organs and are amenable to curative excision, but histologic evidence of grade III immature teratoma or malignancy demands aggressive postoperative chemotherapy to prevent local recurrence.
  • [MeSH-major] Retroperitoneal Neoplasms. Teratoma

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  • [Cites] Ann Surg. 1983 Sep;198(3):398-410 [6684416.001]
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  • (PMID = 15918045.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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66. Idress R, Ahmad Z, Minhas K, Kayani N: Epidermoid cyst of the ovary. J Pak Med Assoc; 2007 May;57(5):263-4
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  • They must be differentiated from mature cystic teratomas of the ovary, and some authors believe them to be monodermal teratomas.

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  • (PMID = 17571487.001).
  • [ISSN] 0030-9982
  • [Journal-full-title] JPMA. The Journal of the Pakistan Medical Association
  • [ISO-abbreviation] J Pak Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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67. Tzukerman M, Rosenberg T, Reiter I, Ben-Eliezer S, Denkberg G, Coleman R, Reiter Y, Skorecki K: The influence of a human embryonic stem cell-derived microenvironment on targeting of human solid tumor xenografts. Cancer Res; 2006 Apr 1;66(7):3792-801
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  • In the current study, we used human embryonic stem cells in order to study the interactions of tumor cells with the surrounding microenvironment of differentiated human cell tissues and structures.
  • Several cancer cell types stably expressing an H2A-green fluorescence protein fusion protein, which allowed tracking of tumor cells, were injected into mature teratomas and developed into tumors.
  • The salient findings were: (a) the observation of growth of tumor cells with high proliferative capacity within the differentiated microenvironment of the teratoma, (b) the identification of invasion by tumor cells into surrounding differentiated teratoma structures, and (c) the identification of blood vessels of human teratoma origin, growing adjacent to and within the cancer cell-derived tumor.
  • Mouse embryonic stem cell-derived teratomas also supported cancer cell growth, but provided a less suitable model for human tumorigenesis studies.
  • [MeSH-minor] Animals. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / therapy. Cell Growth Processes / physiology. Cell Line, Tumor. Embryo, Mammalian / cytology. Green Fluorescent Proteins / biosynthesis. Green Fluorescent Proteins / genetics. Humans. Immunotherapy / methods. Mice. Mice, SCID. Neovascularization, Pathologic / genetics. Neovascularization, Pathologic / pathology. Neovascularization, Pathologic / therapy. Teratoma / blood supply. Teratoma / genetics. Teratoma / pathology. Teratoma / therapy. Transfection. Transplantation, Heterologous

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  • (PMID = 16585206.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 147336-22-9 / Green Fluorescent Proteins
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68. Choudhary S, Fasih N, Mc Innes M, Marginean C: Imaging of ovarian teratomas: appearances and complications. J Med Imaging Radiat Oncol; 2009 Oct;53(5):480-8
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  • [Title] Imaging of ovarian teratomas: appearances and complications.
  • Ovarian teratomas are the most common germ cell neoplasm.
  • Subtypes of teratoma include mature cystic, immature and the monodermal teratomas.
  • The benign cystic teratoma shows typical imaging manifestations and can be complicated by torsion, rupture and uncommonly malignant degeneration.
  • Uncommon subtypes of teratomas include the immature, which is usually malignant at diagnosis.
  • The growing teratoma syndrome is an uncommon complication reported in patients treated for immature teratomas.
  • The monodermal teratomas which include the struma ovarii may also have specific imaging characteristics that should be recognised on imaging.
  • [MeSH-major] Diagnostic Imaging / methods. Image Enhancement / methods. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 19788483.001).
  • [ISSN] 1754-9485
  • [Journal-full-title] Journal of medical imaging and radiation oncology
  • [ISO-abbreviation] J Med Imaging Radiat Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Australia
  • [Number-of-references] 35
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69. Coullin P: [From human andro- and parthenogenesis (hydatidiform moles and benign ovarian teratomas) to cancer]. Gynecol Obstet Fertil; 2005 Jul-Aug;33(7-8):469-82
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  • [Title] [From human andro- and parthenogenesis (hydatidiform moles and benign ovarian teratomas) to cancer].
  • This phenomenon blocks the normal development of parthenogenic and androgenic conceptuses, that is to say benign ovarian teratomas and hydatidiform moles respectively.
  • [MeSH-major] Embryonic Development / genetics. Genomic Imprinting. Hydatidiform Mole / genetics. Ovarian Neoplasms / genetics. Teratoma / genetics. Uterine Neoplasms / genetics


70. Eyssartier E, Harper L, Michel JL, Rivière JP, Vanderbecken S, De Napoli-Cocci S: Rapidly growing mature retroperitoneal teratomas. J Pediatr Hematol Oncol; 2009 Sep;31(9):705-6
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  • [Title] Rapidly growing mature retroperitoneal teratomas.
  • Retroperitoneal mature teratomas are rare benign tumors, most commonly found in neonates and young adults.
  • We report 2 cases of fast-growing retroperitoneal mature teratomas.
  • [MeSH-major] Infant, Premature, Diseases / pathology. Retroperitoneal Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19684525.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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71. Machuca JS, Tejwani D, Niazi M, Diaz-Fuentes G: A large ruptured mediastinal cystic teratoma. J Bronchology Interv Pulmonol; 2010 Jul;17(3):269-72
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  • [Title] A large ruptured mediastinal cystic teratoma.
  • Pathologic examination showed a variety of cell lines consisting of respiratory mucosa, mucous glands, cartilage, smooth muscle, adipose tissue, and pancreatic tissue, results consistent with a mature teratoma.
  • Mature cystic teratomas are usually benign in nature and represent 60% to 70% of mediastinal germ cell tumors; they are found most commonly in young adults.
  • Rupture of a mediastinal cystic teratoma is a rare event and can be a life-threatening condition.

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  • (PMID = 23168900.001).
  • [ISSN] 1944-6586
  • [Journal-full-title] Journal of bronchology & interventional pulmonology
  • [ISO-abbreviation] J Bronchology Interv Pulmonol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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72. Cabibi D, Martorana A, Cappello F, Barresi E, Di Gangi C, Rodolico V: Carcinosarcoma of monoclonal origin arising in a dermoid cyst of ovary: a case report. BMC Cancer; 2006;6:47
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  • BACKGROUND: Transformation of a cystic benign teratoma of the ovary into a "carcinosarcoma" has very rarely been reported and its histogenetic origin is still debated.
  • The tumor showed cystic areas delimited by normal squamous epithelium, with transitional areas through dysplastic epithelium to "in situ" and infiltrating squamous cell carcinoma (SCC).

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  • [Cites] J Clin Pathol. 2002 May;55(5):321-5 [11986333.001]
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  • (PMID = 16509974.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1420311
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73. Bettaieb I, Bellil-Ben Haha S, Zemmel I, Braham E, Bellil K, Mekni A, Kchir N, Haouet S, Zitouna K: [Benign sacrococcygeal teratoma in an adult]. Neurochirurgie; 2007 Aug;53(4):299-302
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign sacrococcygeal teratoma in an adult].
  • Sacrococcygeal teratomas are rare congenital tumors generally discovered at birth.
  • Radical resection must be performed to avoid potentially malignant recurrence even if the primary lesion was benign.
  • We report a case of a benign sacroccygeal teratoma diagnosed in a 25-year-old male and discuss clinical features, pathological considerations and treatment.
  • [MeSH-major] Spinal Cord Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 17543350.001).
  • [ISSN] 0028-3770
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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74. Gonzalez M, Krueger T, Schaefer SC, Ris HB, Perentes JY: Asymptomatic intrapericardial mature teratoma. Ann Thorac Surg; 2010 Jun;89(6):e46-7
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  • [Title] Asymptomatic intrapericardial mature teratoma.
  • Benign mature teratomas are the most common type of germ cell tumors that arise in the anterior mediastinum.
  • Intrapericardial teratomas are a rare manifestation of this tumor type, which are generally diagnosed during infancy because of the heart compression symptoms they produce.
  • Here we report a rare case of intrapericardial mature teratoma that was incidentally discovered in an asymptomatic 51-year-old woman.
  • [MeSH-major] Heart Neoplasms / diagnosis. Pericardium. Teratoma / diagnosis

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  • [Copyright] 2010 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20494011.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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75. Pansky M, Shade D, Moskovitch M, Halperin R, Ben-Ami I, Smorgick N: Inadvertent rupture of benign cystic teratoma does not impair future fertility. Am J Obstet Gynecol; 2010 Nov;203(5):442.e1-4
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  • [Title] Inadvertent rupture of benign cystic teratoma does not impair future fertility.
  • OBJECTIVE: We sought to investigate the reproductive outcomes of women who underwent laparoscopic removal of benign cystic teratoma with or without intraoperative spillage.
  • STUDY DESIGN: The reproductive outcomes of reproductive age women following laparoscopic removal of benign cystic teratoma from 1997 through 2007 were investigated by a telephone questionnaire.
  • RESULTS: In all, 128 reproductive age women underwent benign cystic teratoma removal, and reproductive outcomes were available for 45.
  • CONCLUSION: Intraoperative spillage of benign cystic teratomas does not lead to long-term infertility.
  • [MeSH-major] Intraoperative Complications. Ovarian Neoplasms / surgery. Ovary / injuries. Pregnancy Rate. Teratoma / surgery

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20739009.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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81. Marulaiah M, Gilhotra A, Moore L, Boucaut H, Goh DW: Testicular and paratesticular pathology in children: a 12-year histopathological review. World J Surg; 2010 May;34(5):969-74
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  • Of 27 patients with testicular neoplasms, 55.6% were malignant (29.6% primary and 26% secondary), the principal primary malignancy was yolk sac tumor; the most common benign neoplasms were epidermoid cysts and teratomas.
  • Benign testicular neoplasms occur more frequently than primary malignancies.

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  • [Cites] J Urol. 2003 Dec;170(6 Pt 1):2412-5; discussion 2415-6 [14634440.001]
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  • (PMID = 20151127.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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82. Onol FF, Baytekin F, Dikbas O, Ergönenç T, Tanidir Y: A retroperitoneal bronchogenic cyst mimicking adrenal tumour in an adult: is differential diagnosis truly possible? J Clin Pathol; 2009 Feb;62(2):187-9
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  • A retroperitoneal position for a bronchial cyst is extremely unusual and should be differentiated from other neoplastic lesions.
  • Although histologically they can be differentiated from other lesions, bronchial cysts may show various pathological patterns of differentiation that may cause confusion in differentiating them from cystic teratomas.
  • This is a case of a retroperitoneal bronchogenic cyst featuring uncommon histological findings, which raises the question whether these benign lesions can always be accurately differentiated from teratomatoid cystic neoplasms.

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  • (PMID = 19181637.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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83. Stevens QE, Kattner KA, Chen YH, Rahman MA: Intradural extramedullary mature cystic teratoma: not only a childhood disease. J Spinal Disord Tech; 2006 May;19(3):213-6
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  • [Title] Intradural extramedullary mature cystic teratoma: not only a childhood disease.
  • OBJECTIVE: The authors report on the first case of a spinal intradural extramedullary cystic teratoma in an aged patient.
  • A putative diagnosis of a cystic intradural extramedullary mass was made.
  • RESULTS: A cystic lesion containing hair follicles, cartilage, adipose, and neural tissue was encountered.
  • Pathologic review corroborated the diagnosis of cystic teratoma.
  • CONCLUSIONS: The occurrence of cystic teratomas in the absence of previous surgery or lumbar puncture is uncommon.
  • Though rare, this entity should be included in the differential of cystic intradural spinal cord lesions.
  • [MeSH-major] Paresis / etiology. Spinal Cord Compression / complications. Spinal Cord Compression / diagnosis. Spinal Neoplasms / complications. Spinal Neoplasms / diagnosis. Teratoma / complications. Teratoma / diagnosis

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  • (PMID = 16770222.001).
  • [ISSN] 1536-0652
  • [Journal-full-title] Journal of spinal disorders & techniques
  • [ISO-abbreviation] J Spinal Disord Tech
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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84. Lieb WE: [Tumors and tumor-like lesions of the orbit]. HNO; 2010 Jul;58(7):661-71
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  • The most common orbital tumors in childhood are cystic tumors, such as dermoid and epidermoid cysts.
  • Capillary hemangiomas are the most common primary benign tumors of the orbit and appear mostly in the first year of life.
  • In contrast teratomas are rare and histologically mostly benign.
  • Lymphoproliferative diseases, vascular and cystic tumors in particular are known as tumors of adulthood.

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  • (PMID = 20607507.001).
  • [ISSN] 1433-0458
  • [Journal-full-title] HNO
  • [ISO-abbreviation] HNO
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
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85. Sonn TS, Merritt DF: Anti-NMDA-receptor encephalitis: an adolescent with an ovarian teratoma. J Pediatr Adolesc Gynecol; 2010 Oct;23(5):e141-4
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  • [Title] Anti-NMDA-receptor encephalitis: an adolescent with an ovarian teratoma.
  • BACKGROUND: Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis has been reported to be associated with ovarian teratomas.
  • Imaging revealed an adnexal mass which was surgically removed and confirmed to be a mature teratoma.
  • COMMENTS: Cystic teratomas are one of the most common benign ovarian lesions in children and young women.
  • While an association of ovarian teratomas and paraneoplastic encephalitis is published in the neurologic literature, this association needs to be clarified for the practicing gynecologist who may be asked to consult on these patients.
  • [MeSH-major] Autoantibodies / immunology. Ovarian Neoplasms / complications. Paraneoplastic Syndromes, Nervous System / etiology. Receptors, N-Methyl-D-Aspartate / immunology. Teratoma / complications

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  • [Copyright] Copyright © 2010 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20605495.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Autoantibodies; 0 / Receptors, N-Methyl-D-Aspartate
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86. Tomas D, Lenicek T, Tuckar N, Puljiz Z, Ledinsky M, Kruslin B: Primary ovarian leiomyoma associated with endometriotic cyst presenting with symptoms of acute appendicitis: a case report. Diagn Pathol; 2009;4:25
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  • BACKGROUND: Ovarian leiomyoma is a rare benign tumor that accounts for 0.5 to 1% of all benign ovarian tumors.
  • Additionally, smooth muscle metaplasia of endometriotic stroma, smooth muscle present in mature cystic teratomas, and smooth muscle in the walls of mucinous cystic tumor may explain their occurrence in the ovary in some cases.

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  • (PMID = 19642987.001).
  • [ISSN] 1746-1596
  • [Journal-full-title] Diagnostic pathology
  • [ISO-abbreviation] Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2724421
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87. López JI, de Santamaría IS, Claros IJ, Garmendia M, Gaafar A, Bilbao FJ: Prostatic remnants in mature cystic teratoma of the ovary. Ann Diagn Pathol; 2008 Oct;12(5):378-80
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  • [Title] Prostatic remnants in mature cystic teratoma of the ovary.
  • Mature cystic teratomas of the ovary containing prostatic remnants are reported in 2 women aged 31 and 20 years.
  • Both cases showed the expected histology of mature teratomas with a mixture of ecto- and endodermal structures lying in a fibrous stroma.
  • [MeSH-major] Ovarian Neoplasms / pathology. Prostate / pathology. Teratoma / pathology

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  • (PMID = 18774505.001).
  • [ISSN] 1532-8198
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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88. Hackethal A, Brueggmann D, Bohlmann MK, Franke FE, Tinneberg HR, Münstedt K: Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data. Lancet Oncol; 2008 Dec;9(12):1173-80
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  • [Title] Squamous-cell carcinoma in mature cystic teratoma of the ovary: systematic review and analysis of published data.
  • Up to a quarter of ovarian masses originate from germ cells, and many of these are mature cystic teratomas.
  • The secondary development of malignancy is a rare but well-known phenomenon in patients with ovarian teratomas.
  • Squamous-cell carcinoma accounts for 80% of secondary malignant transformations of ovarian teratomas.
  • Squamous-cell carcinoma in mature cystic teratoma was mainly found in women aged more than 50 years, with high concentrations of squamous-cell-carcinoma antigen and cancer antigen CA125, and with ovarian tumours more than 100 mm in size.
  • [MeSH-major] Carcinoma, Squamous Cell. Ovarian Neoplasms. Teratoma

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  • [ErratumIn] Lancet Oncol. 2009 May;10(5):446
  • (PMID = 19038764.001).
  • [ISSN] 1474-5488
  • [Journal-full-title] The Lancet. Oncology
  • [ISO-abbreviation] Lancet Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Meta-Analysis; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen
  • [Number-of-references] 91
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89. Tekinbas C, Gunduz A, Turedi S: An unusual symptom of cystic teratoma cases. Emerg Med J; 2007 Jun;24(6):449
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  • [Title] An unusual symptom of cystic teratoma cases.
  • [MeSH-major] Mediastinal Neoplasms / radiography. Teratoma / radiography

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  • [Cites] Australas Radiol. 2005 Feb;49(1):53-6 [15727610.001]
  • (PMID = 17513558.001).
  • [ISSN] 1472-0213
  • [Journal-full-title] Emergency medicine journal : EMJ
  • [ISO-abbreviation] Emerg Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2658299
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90. Newsom-Davis T, Poulter D, Gray R, Ameen M, Lindsay I, Papanikolaou K, Butler-Manuel S, Christmas T, Townsend P, Seckl M: Case report: malignant teratoma of the uterine corpus. BMC Cancer; 2009;9:195
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  • [Title] Case report: malignant teratoma of the uterine corpus.
  • BACKGROUND: Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary.
  • Extragonadal teratomas are rare and mainly occur in midline structures.
  • Uterine teratomas are extremely rare with only a few previous case reports, usually involving mature teratomas of the uterine cervix.
  • Initial investigations revealed a benign teratoma of the uterus which was removed.
  • Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy.
  • CONCLUSION: In this report we discuss the aetiology, diagnosis and management of uterine teratomas, and review previous case studies.
  • [MeSH-major] Teratoma / diagnosis. Uterine Neoplasms / diagnosis

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  • (PMID = 19538751.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
  • [Other-IDs] NLM/ PMC2709639
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91. Park EA, Cho JY, Lee MW, Kim SH, Seong CK, Kim SH: MR features of fluid-fluid levels in ovarian masses. Eur Radiol; 2007 Dec;17(12):3247-54
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  • In non-teratomas, we assessed whether SI of the FFLs of benign masses and malignant neoplasms differed using the chi(2) test.
  • FFLs were observed in 66 of 556 ovarian masses (11.9%) on MR images, fat-fluid levels were observed in 11 of 80 teratomas, and FFLs attributed to hemorrhage in 54 of 476 non-teratomas and one twisted teratoma.
  • Non-neoplastic cystic lesions were most common non-teratomas to contain FFLs (27/197, 13.7%), followed by malignant neoplasms (23/177, 13.0%).
  • Benign neoplasms rarely contained FFLs (4/102, 3.9%); those that did were commonly associated with complications such as torsion or inflammation.
  • A hypointense supernatant layer together with a hyperintense dependent layer on T1-weighted images (T1WIs) was significantly more common in malignant neoplasms than in benign masses (P < 0.0001).
  • FFLs occurred in various ovarian masses ranging from benign to malignant neoplasms on MR images.
  • In non-teratomas, a hypointense supernatant layer and a hyperintense dependent layer on T1WIs may favor a diagnosis of malignancy.

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  • (PMID = 17639405.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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92. Bahadirov Z, Serifi MA: [Dermoid cyst presenting with atypical upper extremity neurological symptoms]. Ugeskr Laeger; 2009 Mar 16;171(12):1012
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Dermoid cysts, also known as teratodermoids, are benign tumours thought to originate from multipotent embryonic cells which constitute approx.
  • This is a rare presentation of a mediastinal cystic teratoma presenting with radiating pain and disturbed sensitivity in the right upper extremity.
  • These tumours are generally benign and surgery is the treatment of choice.

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  • (PMID = 19284924.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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93. Guney N, Sayilgan T, Derin D, Ozcan D: Primary carcinoid tumor arising in a mature cystic teratoma of the ovary: a case report. Eur J Gynaecol Oncol; 2009;30(2):223-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary carcinoid tumor arising in a mature cystic teratoma of the ovary: a case report.
  • OBJECTIVE: To present an extremely rare case of a primary carcinoid tumor arising in a mature cystic teratoma of the ovary.
  • Malignant transformation of mature cystic teratoma is an uncommon complication occuring in approximately 1-3% of patients with mature cystic teratoma.
  • Physical examination revealed a smooth, non-painful, 8-9 cm diameter mass in the right anterior pelvis which was diagnosed histologically as carcinoid tumor arising in a mature cystic teratoma.
  • CONCLUSION: This case adds to the rare reports in the literature of a carcinoid of low malignant potential occurring in a mature cystic teratoma.
  • [MeSH-minor] Female. Humans. Middle Aged. Teratoma


94. Guerriero S, Alcazar JL, Pascual MA, Ajossa S, Gerada M, Bargellini R, Virgilio B, Melis GB: Diagnosis of the most frequent benign ovarian cysts: is ultrasonography accurate and reproducible? J Womens Health (Larchmt); 2009 Apr;18(4):519-27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnosis of the most frequent benign ovarian cysts: is ultrasonography accurate and reproducible?
  • OBJECTIVE: To evaluate the reproducibility and the accuracy of B-mode ultrasonographic features of three different kinds of benign ovarian cysts: ovarian endometrioma, mature teratoma, and serous cyst.
  • The histological type of each mass was predicted on the basis of the B-mode typical benign findings, as in the case of endometrioma (groundglass endocystic pattern), cystic teratoma (echogenic pattern with or without acoustic shadow), and serous cyst (anechoic cyst without endocystic vegetations).
  • The interobserver agreement was good for all experts for endometrioma (kappa = 0.66-0.78) and for serous cyst (kappa = 0.82-1), whereas it was moderate or good for cystic teratoma (kappa = 0.51-0.72).
  • Interobserver agreement between experts and highly experienced operators was fair (kappa = 0.33-0.36) for teratoma and good or very good for endometrioma (kappa = 0.70-0.83) and serous cyst (kappa = 0.76-0.82).
  • CONCLUSIONS: Typical features of benign masses using grayscale transvaginal ultrasonography are reproducible even in moderately experienced examiners, although more experience was associated with better interobserver agreement.
  • [MeSH-major] Endometriosis / ultrasonography. Ovarian Cysts / ultrasonography. Ovarian Diseases / ultrasonography. Ovarian Neoplasms / ultrasonography. Teratoma / ultrasonography


95. Iwasa A, Oda Y, Kurihara S, Ohishi Y, Yasunaga M, Nishimura I, Takagi E, Kobayashi H, Wake N, Tsuneyoshi M: Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53- and p16/Rb-dependent cell cycle regulator proteins. Pathol Int; 2008 Dec;58(12):757-64
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  • [Title] Malignant transformation of mature cystic teratoma to squamous cell carcinoma involves altered expression of p53- and p16/Rb-dependent cell cycle regulator proteins.
  • Ovarian mature cystic teratomas (MCT) uncommonly undergo malignant transformation to squamous cell carcinoma (SCC).
  • [MeSH-major] Carcinoma, Squamous Cell / genetics. Cell Transformation, Neoplastic / genetics. Cyclin-Dependent Kinase Inhibitor p16 / genetics. Gene Expression Regulation, Neoplastic. Ovarian Neoplasms / genetics. Teratoma / genetics. Tumor Suppressor Protein p53 / genetics


96. Park SB, Kim JK, Kim KR, Cho KS: Imaging findings of complications and unusual manifestations of ovarian teratomas. Radiographics; 2008 Jul-Aug;28(4):969-83
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Imaging findings of complications and unusual manifestations of ovarian teratomas.
  • Ovarian teratomas can be associated with various complications and demonstrate a wide spectrum of clinical and imaging features.
  • The complications include torsion (16% of ovarian teratomas), rupture (1%-4%), malignant transformation (1%-2%), infection (1%), and autoimmune hemolytic anemia (<1%).
  • In cases of complicated ovarian teratomas, the clinical manifestations provide only limited information and often overlap with those of other diseases.
  • Furthermore, ovarian teratomas may have unusual clinical and imaging manifestations, thereby leading to misdiagnosis.
  • These unusual manifestations include immature teratomas, monodermal teratomas (struma ovarii), combination tumors and collision tumors containing teratomas, and mature cystic teratomas without demonstrable fat or with pure fatty components.
  • To provide adequate treatment and prevent misdiagnosis, it is necessary to be familiar with the imaging findings of both the complications and the unusual manifestations of ovarian teratomas.
  • [MeSH-major] Diagnostic Imaging / methods. Ovarian Neoplasms / complications. Ovarian Neoplasms / diagnosis. Teratoma / complications. Teratoma / diagnosis

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  • (PMID = 18635624.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 53
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97. Schultz KA, Sencer SF, Messinger Y, Neglia JP, Steiner ME: Pediatric ovarian tumors: a review of 67 cases. Pediatr Blood Cancer; 2005 Feb;44(2):167-73
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  • RESULTS: Thirty patients had benign tumors.
  • Thirty-seven patients had malignant tumors: 11 immature teratomas, seven malignant mixed germ cell tumors, seven juvenile granulosa cell tumors, five dysgerminomas, two endodermal sinus tumors, two serous papillary cystadenocarcinomas, one small cell carcinoma, one anaplastic sex-cord tumor, and one undifferentiated sarcoma.
  • Torsion was seen more often in patients with benign tumors (23 vs. 8%); two patients had both torsion and acute appendicitis.

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  • (PMID = 15490488.001).
  • [ISSN] 1545-5009
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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98. Thyavihally YB, Tongaonkar HB, Desai SB: Benign mixed epithelial stromal tumor of the renal pelvis with exophytic growth: case report. Int Semin Surg Oncol; 2005 Sep 9;2:18
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mixed epithelial stromal tumor of the renal pelvis with exophytic growth: case report.
  • BACKGROUND: Mixed epithelial and stromal tumor (MEST) is a distinctive benign composite neoplasm of the kidney predominantly seen in females mostly in the perimenopausal period.
  • She had undergone excision of bilateral ovarian cystic masses for cystic teratoma twelve years earlier.
  • Microscopically, the tumor was composed of large collagenized areas containing bundles of spindle cells and several 'microcysts' lined by cuboidal epithelium suggestive of a benign mixed epithelial stromal tumor.
  • DISCUSSION: Mixed epithelial tumors usually present in perimenopausal women as a partially cystic mass.
  • Tumors are composed of irregular mixtures of cystic and solid areas, glands with variable complexity and distribution and the stromal component is characterized by a spindle cell proliferation.
  • CONCLUSION: MEST is a distinctive benign tumor of the kidney that should be distinguished from other renal neoplasms.

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  • (PMID = 16150156.001).
  • [ISSN] 1477-7800
  • [Journal-full-title] International seminars in surgical oncology : ISSO
  • [ISO-abbreviation] Int Semin Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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99. Hartke DM, Agarwal PK, Palmer JS: Prepubertal male and testicular neoplasms: diagnosis and treatment. Drugs Today (Barc); 2006 Feb;42(2):127-33
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Prepubescent testicular tumors are far more likely to be benign than adult tumors.
  • Teratomas are benign in the pediatric population and constitute the second most commonly reported tumors and, in some series, they are the most common.
  • The remaining tumors are far more rare and often benign.
  • Regardless of tumor type, with prompt diagnosis and treatment long-term survival is excellent.

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  • (PMID = 16541189.001).
  • [ISSN] 1699-3993
  • [Journal-full-title] Drugs of today (Barcelona, Spain : 1998)
  • [ISO-abbreviation] Drugs Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Spain
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100. Kalish GM, Patel MD, Gunn ML, Dubinsky TJ: Computed tomographic and magnetic resonance features of gynecologic abnormalities in women presenting with acute or chronic abdominal pain. Ultrasound Q; 2007 Sep;23(3):167-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • For a woman in her reproductive years, the most common adnexal masses are physiological cysts, endometriomas, and cystic teratomas.
  • If a gynecologic pathology is discovered on CT or MRI, an immediate follow-up ultrasound need not be pursued if the lesion can be characterized as benign, needing immediate surgical intervention, or a variant of normal anatomy.
  • If, on the other hand, findings demonstrate a mass that either is uncharacteristic of a benign lesion, has an indeterminate risk for malignancy, or demonstrates suspicious characteristics for malignancy (such as enhancing mural nodules), further evaluation by serial ultrasound, biochemical marker, and/or CT or MRI is warranted.






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