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1. Lo Curto M, D'Angelo P, Cecchetto G, Klersy C, Dall'Igna P, Federico A, Siracusa F, Alaggio R, Bernini G, Conte M, De Laurentis T, Di Cataldo A, Inserra A, Santoro N, Tamaro P, Indolfi P: Mature and immature teratomas: results of the first paediatric Italian study. Pediatr Surg Int; 2007 Apr;23(4):315-22
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  • Teratoma is the most common germ cell tumour in childhood; mature (MT) and immature teratomas (IT) are benign tumours, but if they recur, they can be in some cases malignant.
  • The T grading was 1 in 14 cases, 2 in 26, 3 in 16; 28 had gonadic T (17 ovary, 11 testis), 28 extragonadic (sacrococcygeal 19, mediastinic 3, retroperitoneal 2, other sites 4).
  • Eight IT (14.2%) relapsed (four ovary, three sc, one retroperitoneal).
  • [MeSH-major] Ovarian Neoplasms / epidemiology. Teratoma / epidemiology. Testicular Neoplasms / epidemiology

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  • (PMID = 17333214.001).
  • [ISSN] 0179-0358
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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2. Ulbright TM: Germ cell tumors of the gonads: a selective review emphasizing problems in differential diagnosis, newly appreciated, and controversial issues. Mod Pathol; 2005 Feb;18 Suppl 2:S61-79
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  • The most dramatic examples of the latter are the frequency of dermoid cyst in the ovary compared to the testis and the reverse pertaining to embryonal carcinoma.
  • Within the teratoma group, there is strong evidence that ovarian and prepubertal testicular teratomas are derived from benign germ cells, a pathogenesis that likely applies also to the rare dermoid cysts and uncommon epidermoid cysts of the testis.
  • As expected, given the foregoing, teratomas in boys are clinically benign, whereas in postpubertal males they are malignant, independent of their degree of immaturity.
  • Fetal-type tissues alone are not sufficient for a diagnosis of immature teratoma.
  • Further differences between the teratomatous tumors in the two gonads are the relative frequency of monodermal teratomas in the ovary in contrast to the testis, where only one subset, carcinoids, is seen with any frequency.
  • When uncommon somatic-type malignancies (usually squamous cell carcinoma) occur in mature cystic teratomas of the ovary, this is a de novo form of malignant transformation; similar tumors in the testis, a very rare event, represent overgrowth of teratomatous elements that originated from malignant, nonteratomatous germ cell tumors and, therefore, had previously undergone malignant transformation.
  • Yolk sac tumor continues to be confused occasionally with clear cell carcinoma of the ovary.
  • Glandular ('endometrioid-like') yolk sac tumors mimic endometrioid carcinomas; predominant or pure hepatoid yolk sac tumors cause concern for metastatic hepatocellular carcinoma or, in the ovary, primary hepatoid carcinoma, and solid patterns, especially in limited samplings, may be misinterpreted as germinoma.
  • Choriocarcinoma is rare in both gonads, and those in the ovary must be distinguished from metastatic tumors of placental origin.
  • Mixed germ cell tumors (which may show almost any combination of components) are common in the testis but rare in the ovary.
  • These tumors, which are constituted by innumerable embryoid bodies, almost always contain teratomatous glands in minor amounts, and one way of viewing the polyembryoma is to consider it the most immature form of teratoma.
  • [MeSH-minor] Antigens, CD30 / analysis. Diagnosis, Differential. Female. Germinoma / metabolism. Germinoma / pathology. Humans. Immunohistochemistry. Keratin-7. Keratins / analysis. Male. Organic Cation Transport Proteins / analysis. Proto-Oncogene Proteins c-kit / analysis. Teratoma / metabolism. Teratoma / pathology

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  • (PMID = 15761467.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD30; 0 / KRT7 protein, human; 0 / Keratin-7; 0 / Organic Cation Transport Proteins; 0 / solute carrier family 22 (organic cation transporter), member 3; 68238-35-7 / Keratins; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
  • [Number-of-references] 132
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3. Chavan SS, Yenni VV: Mandible like structure with fourteen teeth in a benign cystic teratoma. Indian J Pathol Microbiol; 2009 Oct-Dec;52(4):595-6
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  • [Title] Mandible like structure with fourteen teeth in a benign cystic teratoma.
  • [MeSH-major] Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / pathology. Teratoma / diagnosis. Teratoma / pathology
  • [MeSH-minor] Adult. Female. Humans. Mandible / pathology. Ovary / pathology. Tooth / pathology

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  • (PMID = 19805995.001).
  • [ISSN] 0974-5130
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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4. Piura B, Rabinovich A, Shaco-Levy R: Squamous cell carcinoma arising in ovarian mature cystic teratoma with isolated metastasis to the appendix. J Obstet Gynaecol; 2009 Jan;29(1):71-3
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  • [Title] Squamous cell carcinoma arising in ovarian mature cystic teratoma with isolated metastasis to the appendix.
  • [MeSH-major] Appendiceal Neoplasms / secondary. Carcinoma, Squamous Cell / secondary. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19280511.001).
  • [ISSN] 1364-6893
  • [Journal-full-title] Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
  • [ISO-abbreviation] J Obstet Gynaecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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5. Cerimagić Z, Pilav I, Banjanović B: [Surgery approach of mediastinal benign teratomas in childhood]. Med Arh; 2006;60(6 Suppl 1):47-9
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  • [Title] [Surgery approach of mediastinal benign teratomas in childhood].
  • [Transliterated title] Hirurski tretman medijastinalnih benignih teratoma kod djece.
  • Benign teratomas are benign tumors of germinative cells which originate from gonad tissue, and are primarily located in the gonads (ovary and testes).
  • Surgical aproach to treating these teratomas is completely removing mediastinal benign teratomas by anterolateral thoracotomy or transversal sternotomy.
  • The following case report describes teratomas localized in anterior and middle mediastinum, which are surgically completely removed and pathohystologically described as mature cystic teratoma.
  • [MeSH-major] Mediastinal Neoplasms / surgery. Teratoma / surgery

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  • (PMID = 18172981.001).
  • [Journal-full-title] Medicinski arhiv
  • [ISO-abbreviation] Med Arh
  • [Language] bos
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Bosnia and Herzegovina
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6. Yamagami W, Banno K, Kawaguchi M, Yanokura M, Kuwabara Y, Hirao N, Susumu N, Tsukazaki K, Aoki D: Use of the collagen gel droplet embedded drug sensitivity test to determine drug sensitivity against ovarian mature cystic teratoma with malignant transformation to adenocarcinoma: a case report. Chemotherapy; 2007;53(2):137-41
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  • [Title] Use of the collagen gel droplet embedded drug sensitivity test to determine drug sensitivity against ovarian mature cystic teratoma with malignant transformation to adenocarcinoma: a case report.
  • We report the use of this test in the choice of adjuvant chemotherapy for treatment of a rare case of ovarian cancer involving malignant transformation of ovarian mature cystic teratoma.
  • The histopathological diagnosis was adenocarcinoma, mature cystic teratoma with malignant transformation, stage IV.
  • [MeSH-major] Adenocarcinoma / drug therapy. Antineoplastic Combined Chemotherapy Protocols. Collagen Type I. Drug Screening Assays, Antitumor. Ovarian Neoplasms / drug therapy. Teratoma / drug therapy

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  • [Copyright] Copyright 2007 S. Karger AG, Basel.
  • (PMID = 17308380.001).
  • [ISSN] 1421-9794
  • [Journal-full-title] Chemotherapy
  • [ISO-abbreviation] Chemotherapy
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Collagen Type I; 0 / Gels; BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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7. Kunieda E, Hara H, Morikawa Y, Hirobe S, Kamagata S, Kubo A: Accumulation of gallium-67 within mature and immature teratoma in pediatric patients: investigation for the uptake mechanism. Ann Nucl Med; 2008 Apr;22(3):207-13
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  • [Title] Accumulation of gallium-67 within mature and immature teratoma in pediatric patients: investigation for the uptake mechanism.
  • OBJECTIVE: We encountered cases of mature and immature teratoma with positive uptake of (67)Ga.
  • The origins of the immature teratomas were retroperitoneum in two cases, an ovary and a sacrococcygeal region.
  • RESULTS: Of the 14 children, 5 (one with immature and four with mature subtype) showed positive (67)Ga uptake within tumors, which originated from the retroperitoneum in the 3 boys, and from the ovary in the 2 girls.
  • All had typical CT findings of teratoma, including calcifications, fat components, cystic areas, and solid parts. (67)Ga accumulation in the four mature teratomas appeared discretely strong, and was considered to correspond with intralesional calcifications.
  • However, in the remaining one immature teratoma, the gallium distribution was diffuse within the tumor.
  • CONCLUSIONS: A high-uptake ratio of (67)Ga in benign teratoma was indicated.
  • [MeSH-major] Calcinosis / radionuclide imaging. Gallium Radioisotopes / pharmacokinetics. Ovarian Neoplasms / radionuclide imaging. Retroperitoneal Neoplasms / radionuclide imaging. Teratoma / radionuclide imaging

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  • (PMID = 18498036.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Gallium Radioisotopes; 0 / Radiopharmaceuticals
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8. Devoize L, Collangettes D, Le Bouëdec G, Mishellany F, Orliaguet T, Dallel R, Baudet-Pommel M: Giant mature ovarian cystic teratoma including more than 300 teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Mar;105(3):e76-9
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  • [Title] Giant mature ovarian cystic teratoma including more than 300 teeth.
  • Preoperative diagnosis of malignant tumors arising from mature cystic teratoma (MCT) of the ovary is not easy; malignant tumors are mostly diagnosed only postoperatively.
  • This article reports a rare case of a giant, benign MCT of the ovary in a young woman (25 years old).
  • [MeSH-major] Antigens, Neoplasm / analysis. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18280952.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / NBR1 protein, human; 0 / Proteins; 0 / Serpins; 0 / alpha-Fetoproteins; 0 / squamous cell carcinoma-related antigen
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9. Chang HJ, Han SH, Lee JR, Jee BC, Lee BI, Suh CS, Kim SH: Impact of laparoscopic cystectomy on ovarian reserve: serial changes of serum anti-Müllerian hormone levels. Fertil Steril; 2010 Jun;94(1):343-9
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  • PATIENT(S): Twenty women with benign ovarian masses participated; endometrioma [13], mature teratoma [6], and mucinous cystadenoma [1].
  • Volumes of total ovary and ovarian mass were measured by 3D ultrasonography before operation.
  • [MeSH-major] Anti-Mullerian Hormone / blood. Laparoscopy / adverse effects. Ovarian Cysts / blood. Ovarian Cysts / ultrasonography. Ovary / ultrasonography

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  • [Copyright] Copyright (c) 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
  • (PMID = 19345350.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 80497-65-0 / Anti-Mullerian Hormone
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10. Wang PC, Yang TL, Pan HB: CT images of a malignant-transformed ovarian mature cystic teratoma with rupture: a case report. Korean J Radiol; 2008 Sep-Oct;9(5):458-61
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  • [Title] CT images of a malignant-transformed ovarian mature cystic teratoma with rupture: a case report.
  • A malignant transformation or a tumor rupture is a rare complication of ovarian mature cystic teratoma (MCT).
  • [MeSH-major] Ovarian Neoplasms / pathology. Ovarian Neoplasms / radiography. Teratoma / pathology. Teratoma / radiography. Tomography, X-Ray Computed

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  • (PMID = 18838856.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627209
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11. Rim SY, Kim SM, Choi HS: Struma ovarii showing clinical characteristics of ovarian malignancy. Int J Gynecol Cancer; 2005 Nov-Dec;15(6):1156-9
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  • Struma ovarii is a rare form of ovarian neoplasm, composed entirely or predominantly of thyroid tissue and generally a benign germ cell tumor of the ovary.
  • We experienced a rare case of a postmenopausal woman with benign struma ovarii associated with massive ascites, a complex pelvic mass.
  • [MeSH-major] Biomarkers, Tumor / blood. CA-125 Antigen / blood. Ovarian Neoplasms / pathology. Struma Ovarii / pathology. Teratoma / pathology

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  • (PMID = 16343201.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen
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12. Karpelowsky JS, Hei ER, Matthews K: Laparoscopic resection of benign ovarian tumours in children with gonadal preservation. Pediatr Surg Int; 2009 Mar;25(3):251-4
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  • [Title] Laparoscopic resection of benign ovarian tumours in children with gonadal preservation.
  • Histology was of a mature teratoma in ten cases and simple cyst in two.
  • Six patients underwent routine ultrasonographic follow-up at 2-5 months at which time the involved ovary assumed a size and shape and blood flow comparable to the contra-lateral ovary in five patients.
  • In one patient the affected side was smaller, 8.6 ml compared to 10 ml on the contra-lateral ovary.
  • CONCLUSION: Laparoscopic cystectomy with ovarian preservation can be successfully applied to benign ovarian tumours.
  • [MeSH-major] Ovarian Neoplasms / surgery. Ovary / surgery

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  • (PMID = 19184048.001).
  • [ISSN] 1437-9813
  • [Journal-full-title] Pediatric surgery international
  • [ISO-abbreviation] Pediatr. Surg. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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13. Kim D, Cho HC, Park JW, Lee WA, Kim YM, Chung PS, Park SG, Ahn WS, Han SJ, Park CH: Struma ovarii and peritoneal strumosis with thyrotoxicosis. Thyroid; 2009 Mar;19(3):305-8
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  • BACKGROUND: Struma ovarii is a highly specialized form of mature ovarian teratoma consisting of thyroid tissue and exhibiting all the histological features of the thyroid gland.
  • In rare cases, benign thyroid tissue may spread to the peritoneal cavity, and pathologic examination of the peritoneal implants shows multiple nodules of varying sizes of mature thyroid tissue similar to struma ovarii.
  • [MeSH-minor] Female. Humans. Middle Aged. Ovary / pathology. Whole Body Imaging

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  • (PMID = 19265502.001).
  • [ISSN] 1557-9077
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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14. Barbancho DC, Novillo IC, Vázquez AG, Díaz ML, Sánchez RT, Gordo MB: [Laparoscopy for ovarian tumors in children]. Cir Pediatr; 2007 Jan;20(1):15-8
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  • [Transliterated title] La laparoscopia en el manejo de los tumores ováiricos en la infancia.
  • RESULTS: 21 benign teratomas and one osteosarcoma metastasis were observed in this group of 22 patients.
  • In 8 girls (36.4%) were performed adnexectomy, in 11 (50%) ooforectomy and in three cases (13.6%) the cyst was enucleated with preservation on the ovary.
  • [MeSH-major] Laparoscopy / methods. Ovarian Neoplasms / surgery. Teratoma / surgery

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  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 17489487.001).
  • [ISSN] 0214-1221
  • [Journal-full-title] Cirugía pediátrica : organo oficial de la Sociedad Española de Cirugía Pediátrica
  • [ISO-abbreviation] Cir Pediatr
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
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15. Pranesh N, Menasce LP, Wilson MS, O'Dwyer ST: Pseudomyxoma peritonei: unusual origin from an ovarian mature cystic teratoma. J Clin Pathol; 2005 Oct;58(10):1115-7
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  • [Title] Pseudomyxoma peritonei: unusual origin from an ovarian mature cystic teratoma.
  • The one exception to this is the presentation of a mature ovarian cystic teratoma as PMP where the appendix is normal.
  • [MeSH-major] Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology. Teratoma / pathology

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  • [Cites] Am J Surg Pathol. 2000 Nov;24(11):1447-64 [11075847.001]
  • [Cites] Cancer. 2001 Jul 1;92(1):85-91 [11443613.001]
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  • (PMID = 16189164.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1770748
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16. Liberis V, Tsikouras P, Sivridis E, Dadidou M, Koutlaki N, Galazios G: Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report. Clin Exp Obstet Gynecol; 2008;35(2):151-2
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  • [Title] Irregular dental structures in a benign ovarian cystic teratoma (dermoid cyst): case report.
  • Mature cystic teratomas, often referred to as dermoid cysts, are the most common germ cell tumors of the ovary in women of reproductive age.

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  • (PMID = 18581775.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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17. Pansky M, Shade D, Moskovitch M, Halperin R, Ben-Ami I, Smorgick N: Inadvertent rupture of benign cystic teratoma does not impair future fertility. Am J Obstet Gynecol; 2010 Nov;203(5):442.e1-4
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  • [Title] Inadvertent rupture of benign cystic teratoma does not impair future fertility.
  • OBJECTIVE: We sought to investigate the reproductive outcomes of women who underwent laparoscopic removal of benign cystic teratoma with or without intraoperative spillage.
  • STUDY DESIGN: The reproductive outcomes of reproductive age women following laparoscopic removal of benign cystic teratoma from 1997 through 2007 were investigated by a telephone questionnaire.
  • RESULTS: In all, 128 reproductive age women underwent benign cystic teratoma removal, and reproductive outcomes were available for 45.
  • CONCLUSION: Intraoperative spillage of benign cystic teratomas does not lead to long-term infertility.
  • [MeSH-major] Intraoperative Complications. Ovarian Neoplasms / surgery. Ovary / injuries. Pregnancy Rate. Teratoma / surgery

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20739009.001).
  • [ISSN] 1097-6868
  • [Journal-full-title] American journal of obstetrics and gynecology
  • [ISO-abbreviation] Am. J. Obstet. Gynecol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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18. Song YJ, Ryu SY, Choi SC, Lee ED, Lee KH, Cho SY: Adenocarcinoma arising from the respiratory ciliated epithelium in a benign cystic teratoma of the ovary. Arch Gynecol Obstet; 2009 Oct;280(4):659-62
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  • [Title] Adenocarcinoma arising from the respiratory ciliated epithelium in a benign cystic teratoma of the ovary.
  • Benign cystic teratoma of the ovary (BCTO) is the most common benign ovarian tumor, accounting for 15-20% of all ovarian tumors.
  • Adenocarcinoma arising from mature cystic teratoma is extremely rare.
  • [MeSH-major] Adenocarcinoma / pathology. Ovarian Neoplasms / pathology. Ovary / pathology. Teratoma / pathology

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  • (PMID = 19224233.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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19. Sun CL, Yang L: [Ovarian mature cystic teratoma with gliomatosis peritonei: report of a case]. Zhonghua Bing Li Xue Za Zhi; 2009 Sep;38(9):646
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  • [Title] [Ovarian mature cystic teratoma with gliomatosis peritonei: report of a case].
  • [MeSH-major] Glioma / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Peritoneal Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 20079202.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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20. D'Angelo E, Dadmanesh F, Pecorelli S, Prat J: Squamous cell carcinoma of the ovary arising from a mucinous cystic tumor of endocervical (müllerian) type. Int J Gynecol Pathol; 2010 Nov;29(6):529-32
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  • [Title] Squamous cell carcinoma of the ovary arising from a mucinous cystic tumor of endocervical (müllerian) type.
  • Primary squamous cell carcinoma of the ovary is extremely rare.
  • We studied a 58-year-old woman in whom a keratinizing squamous cell carcinoma of the ovary had arisen from a mucinous cystic tumor of endocervical (müllerian) type.
  • The tumor was interpreted initially as a transitional cell carcinoma of the ovary with marked squamous differentiation, but there was no evidence of either transitional cell carcinoma or malignant Brenner tumor.
  • Furthermore, features of dermoid cyst (mature cystic teratoma), endometriosis, or adenosquamous carcinoma were not seen.
  • The mucinous columnar epithelial component was largely benign and only focally proliferative or borderline.

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  • [CommentIn] Int J Gynecol Pathol. 2011 Jul;30(4):396-7 [21623198.001]
  • (PMID = 20881861.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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21. Zwiesler D, Lewis SR, Choo YC, Martens MG: A case report of an ovarian lipoma. South Med J; 2008 Feb;101(2):205-7
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  • This is a case report of a lipoma of an ovary not associated with a teratoma or an hyperandrogenic state.
  • Microscopic examination demonstrated a pattern of proliferation of benign adipose tissue with focal areas of fibrovascular septae and no other tissue of different origin.
  • Thus, it appears that lipomas of the ovary are rare, but can occur.

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  • (PMID = 18364627.001).
  • [ISSN] 1541-8243
  • [Journal-full-title] Southern medical journal
  • [ISO-abbreviation] South. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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22. Szpakowski M, Nowińska A, Kufelnicka M, Komorowski D, Wilczyński JR: [Laparoscopy or laparotomy in the treatment of ovarian teratomas?]. Ginekol Pol; 2006 Jul;77(7):502-9
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  • BACKGROUND: Mature cystic teratomas (dermoid cyst), are the most common germ cell tumours of the ovary in women of reproductive age.
  • MATERIALS AND METHODS: 81 patients who had surgery in 3rd Departament of Gynecology and Obstetrics, University of Medicine, Lódź, from 2000 to 2005 for benign cystic teratomas were analyzed.
  • All removed lesions histologically appeared benign cystis ovarian teratomas without any signs of malignancy.
  • One of the possibility of ovarian teratoma's treatment is operative laparoscopy.
  • [MeSH-major] Laparoscopy. Ovarian Neoplasms / diagnosis. Ovarian Neoplasms / surgery. Teratoma / diagnosis. Teratoma / surgery

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  • (PMID = 17076199.001).
  • [ISSN] 0017-0011
  • [Journal-full-title] Ginekologia polska
  • [ISO-abbreviation] Ginekol. Pol.
  • [Language] pol
  • [Publication-type] Journal Article
  • [Publication-country] Poland
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23. Ukita S, Koshiyama M, Ohnaka M, Miyagawa N, Yamanishi Y, Nishimura F, Nagura M, Kim T, Hirose M, Shirase T, Kobayashi H, Ozasa H: Retroperitoneal lipoma arising from the urinary bladder. Rare Tumors; 2009;1(1):e13
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  • Retroperitoneal benign lipomas are extremely rare and represent about 2.9% of all primary retroperitoneal tumors.
  • We experienced a case of a retroperitoneal lipoma simulating an ovarian mature cystic teratoma.

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  • (PMID = 21139884.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994430
  • [Keywords] NOTNLM ; lipoma / magnetic resonance imaging. / ovarian mature cystic teratoma / retroperitoneum / urinary bladder
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24. Tyler KL, Bell MC, Ziebarth JA: A rare case of squamous cell carcinoma arising in a mature cystic teratoma of the ovary. S D Med; 2007 Oct;60(10):401-3
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  • [Title] A rare case of squamous cell carcinoma arising in a mature cystic teratoma of the ovary.
  • Mature cystic teratoma is a common benign adnexal tumor in females.
  • We describe a 43-year-old female with a 10 cm left ovarian mature cystic teratoma with the rare finding of squamous cell carcinoma.
  • [MeSH-major] Neoplasms, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18019775.001).
  • [ISSN] 0038-3317
  • [Journal-full-title] South Dakota medicine : the journal of the South Dakota State Medical Association
  • [ISO-abbreviation] S D Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Venizelos ID, Tatsiou ZA, Roussos D, Karagiannis V: A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma. Onkologie; 2009 Jun;32(6):353-5
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  • [Title] A case of sebaceous carcinoma arising within a benign ovarian cystic teratoma.
  • BACKGROUND: Mature cystic teratoma, also known as dermoid cyst, is the most common germ cell tumor of the ovary.
  • Malignant change in a component of a mature ovarian teratoma is rare, occurring in less than 2% of cases, with squamous cell carcinoma corresponding to 80% of such neoplasms.
  • Abdominal and pelvic ultrasound as well as computed tomography demonstrated a heterogenic tumor of the right ovary.
  • Histological examination of the tumor showed features of a well-differentiated sebaceous carcinoma arising within a mature cystic teratoma.
  • [MeSH-major] Adenocarcinoma, Sebaceous / diagnosis. Neoplasms, Multiple Primary / diagnosis. Ovarian Cysts / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • [Copyright] Copyright 2009 S. Karger AG, Basel.
  • (PMID = 19521124.001).
  • [ISSN] 1423-0240
  • [Journal-full-title] Onkologie
  • [ISO-abbreviation] Onkologie
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Switzerland
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26. Mekaru K, Kamiyama S, Masamoto H, Yagi C, Hirakawa M, Inamine M, Nagai Y, Sakumoto K, Aoki Y: Squamous cell carcinoma arising in an ovarian mature cystic teratoma complicating pregnancy: a case report. Arch Gynecol Obstet; 2008 Sep;278(3):287-90
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  • [Title] Squamous cell carcinoma arising in an ovarian mature cystic teratoma complicating pregnancy: a case report.
  • BACKGROUND: The question of whether patients with pure stage I squamous cell carcinoma in a mature cystic teratoma (MCT) should undergo conservative surgery, or postoperative adjuvant treatment remains unresolved.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Pregnancy Complications, Neoplastic / pathology. Teratoma / pathology


27. Schmidt D, Kommoss F: [Teratoma of the ovary. Clinical and pathological differences between mature and immature teratomas]. Pathologe; 2007 May;28(3):203-8
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  • [Title] [Teratoma of the ovary. Clinical and pathological differences between mature and immature teratomas].
  • Teratomas are the most frequent germ cell tumors of the ovary.
  • Mature teratomas are benign tumors, which are most often composed of derivatives of two or three germ cell layers.
  • Grade 0 represents a mature teratoma.
  • Both in cases of mature and immature teratoma, peritoneal implants can be found (gliomatosis peritonei), which are also graded.
  • Gliomatosis peritonei is most likely derived from metaplasia of subperitoneal stem cells; it does not represent a metastatic disease of the ovarian teratoma.
  • [MeSH-major] Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 17396268.001).
  • [ISSN] 0172-8113
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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28. Rim SY, Kim SM, Choi HS: Malignant transformation of ovarian mature cystic teratoma. Int J Gynecol Cancer; 2006 Jan-Feb;16(1):140-4
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  • [Title] Malignant transformation of ovarian mature cystic teratoma.
  • There have been few studies concerning the clinical pathology of malignant transformation arising in ovarian mature cystic teratoma (MCT).
  • Accordingly, it is considered helpful for preventing and early detection of the malignant transformation to have regular ovary examination through pelvic ultrasonogram during the reproductive age.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Ovarian Neoplasms / pathology. Ovarian Neoplasms / therapy. Teratoma / pathology. Teratoma / therapy

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  • (PMID = 16445624.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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29. Driss M, Limaiem F, Mrad K, Charfi L, Abbes I, Sassi S, Hechiche M, Saadi A, Ben Romdhane K: [Malignant degeneration of benign cystic teratoma of the ovary with synchronous mediastinal teratoma. A case report]. Rev Med Interne; 2009 Apr;30(4):369-71
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  • [Title] [Malignant degeneration of benign cystic teratoma of the ovary with synchronous mediastinal teratoma. A case report].
  • [Transliterated title] Association synchrone d'un tératome de l'ovaire cancérisé associé à un tératome du médiastin. A propos d'un cas.
  • Squamous cell carcinoma arising in mature cystic teratoma of the ovary is an uncommon complication occurring usually in elderly woman.
  • We present an unusual case of a post-menopausal woman with a synchronous mediastinum teratoma.
  • While ovary tumor was symptomatic, mediastinal teratoma was an incidental finding.

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  • (PMID = 18722037.001).
  • [ISSN] 0248-8663
  • [Journal-full-title] La Revue de medecine interne
  • [ISO-abbreviation] Rev Med Interne
  • [Language] FRE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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30. Shelekhova KV, Hejda V, Kazakov DV, Michal M: Mature cystic teratoma of the ovary with male accessory sexual glands including seminal vesicles, prostatic tissue, and bulbo-urethral glands: a case report. Virchows Arch; 2008 Jan;452(1):109-11
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  • [Title] Mature cystic teratoma of the ovary with male accessory sexual glands including seminal vesicles, prostatic tissue, and bulbo-urethral glands: a case report.
  • We present an extremely rare case of a benign cystic ovarian teratoma with structures of male accessory sexual glands.
  • A unilocular cystic tumor, measuring 5 cm in the largest diameter, was found in her right ovary and was removed.
  • The teratoma contained epidermis, skin appendages, respiratory and intestinal epithelia, cartilage, muscle, and nervous and connective tissue.
  • To our knowledge, this is the first case in the English literature describing seminal vesicles associated with prostatic tissue and bulbo-urethral glands in a mature ovarian teratoma.
  • [MeSH-major] Bulbourethral Glands / pathology. Ovarian Neoplasms / pathology. Prostate / pathology. Seminal Vesicles / pathology. Teratoma / pathology

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  • [Cites] Histopathology. 2004 Sep;45(3):303-5 [15330814.001]
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  • (PMID = 18066589.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] EC 3.1.3.2 / Acid Phosphatase; EC 3.1.3.2 / prostatic acid phosphatase; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.4.21.77 / Prostate-Specific Antigen
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31. Koshiba H: Severe chemical peritonitis caused by spontaneous rupture of an ovarian mature cystic teratoma: a case report. J Reprod Med; 2007 Oct;52(10):965-7
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  • [Title] Severe chemical peritonitis caused by spontaneous rupture of an ovarian mature cystic teratoma: a case report.
  • CASE: A spontaneously ruptured ovarian mature cystic teratoma was left untreated for >2 weeks, and chemical peritonitis lasted for 1 year.
  • [MeSH-major] Ovarian Neoplasms / complications. Peritonitis / etiology. Teratoma / complications

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  • (PMID = 17977177.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antimetabolites; 0 / Glucocorticoids; 0 / Immunosuppressive Agents
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32. Briones-Landa CH, Ayala-Yáñez R, Leroy-López L, Anaya-Coeto H, Santarosa-Pérez MA, Reyes-Muñoz E: [Comparison of laparoscopic vs. laparotomy treatment in ovarian teratomas]. Ginecol Obstet Mex; 2010 Oct;78(10):527-32
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  • BACKGROUND: Benign cystic teratoma is one of the most common benign tumors of the ovary, according to international series represents between 44 and 62% of all ovarian tumors diagnosed in women younger than 40 years.
  • MATERIALS AND METHOD: Retrospective, clinical series study involving 169 cases of ovarian teratomas operated at the Instituto Nacional de Perinatología Isidro Espinosa de los Reyes in the period comprehended between 2000-2008.
  • Surgical bleeding: 55.7 +/- 21.4 mL vs. 91.6 +/- 29.2 mL (p < 0.0001), hospital stay: 1.6 +/- 0.57 vs. 2.7 +/- 0.42 days (p < 0.0001), surgical time: 110.3 +/- 27.2 vs. 83.6 +/- 26.9 minutes (p < 0.0001), teratoma size: 7.2 +/- 2.3 vs. 11.5 +/- 4.2 cm (p < 0.0001) in groups 1 and 2, respectively.
  • Teratoma rupture had 57.8% incidence (59 cases) in group 1, and 16.4% in group 2 (11 cases).
  • [MeSH-major] Laparoscopy. Laparotomy. Ovarian Neoplasms / surgery. Teratoma / surgery

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  • (PMID = 21966769.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Comparative Study; English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] Mexico
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen
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33. Mülayim B, Gürakan H, Dagli V, Mülayim S, Aydin O, Akkaya H: Unaware of a giant serous cyst adenoma: a case report. Arch Gynecol Obstet; 2006 Mar;273(6):381-3
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  • The single most common benign ovarian neoplasm is the benign cystic teratoma; however, according to some studies it is serous cyst adenoma.
  • At laparotomy, a giant, totally cystic, vascularized and smooth mass attached to the right ovary was encountered, lying between the symphysis and the xiphoid.

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  • (PMID = 16249904.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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34. Ishikawa M, Nakayama K, Yeasmin S, Katagiri A, Iida K, Nakayama N, Miyazaki K: [Paclitaxel + carboplatin (TC)-resistant stage Ic squamous cell carcinomas arising in mature cystic teratomas of the ovary]. Gan To Kagaku Ryoho; 2010 Apr;37(4):747-52
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  • [Title] [Paclitaxel + carboplatin (TC)-resistant stage Ic squamous cell carcinomas arising in mature cystic teratomas of the ovary].
  • Malignant transformation of an ovarian mature cystic teratoma is very rare; it arises in about 1-2% of all dermoid cysts.
  • In Case 1, a 78-year-old woman was diagnosed with squamous cell carcinoma arising from a mature cystic teratoma of the ovary after undergoing right salpingo-oophorectomy (RSO).
  • The results of TAE, however, showed that it may be an effective second-line therapy for recurrent squamous cell carcinoma arising from a mature cystic teratoma.

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  • (PMID = 20414041.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] BG3F62OND5 / Carboplatin; P88XT4IS4D / Paclitaxel
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35. Domínguez-Rosado I, Michel J, Ortiz-Hidalgo C: Ovarian mature cystic teratoma exhibiting well-differentiated cerebellum in a 14-year-old female. Pediatr Dev Pathol; 2005 Mar-Apr;8(2):247-9
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  • [Title] Ovarian mature cystic teratoma exhibiting well-differentiated cerebellum in a 14-year-old female.
  • [MeSH-major] Cerebellum / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 15747101.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Glial Fibrillary Acidic Protein; 0 / Mucin-1; 0 / Neurofilament Proteins
  • [Number-of-references] 15
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36. Lai PF, Hsieh SC, Chien JC, Fang CL, Chan WP, Yu C: Malignant transformation of an ovarian mature cystic teratoma: computed tomography findings. Arch Gynecol Obstet; 2005 Apr;271(4):355-7
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  • [Title] Malignant transformation of an ovarian mature cystic teratoma: computed tomography findings.
  • INTRODUCTION: The malignant transformation of an ovarian mature cystic teratoma is rare.
  • Computed tomography images showed a left adnexal mass with fat, calcification and soft tissue components, and areas of invasion through the teratoma wall.
  • OUTCOME: The histologic diagnosis was compatible with a squamous cell carcinoma arising from a mature cystic teratoma of the ovary.
  • [MeSH-major] Carcinoma, Squamous Cell / radiography. Ovarian Neoplasms / pathology. Ovarian Neoplasms / radiography. Teratoma / pathology. Teratoma / radiography. Tomography, X-Ray Computed / methods

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  • (PMID = 15551144.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CA-125 Antigen
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37. Cabibi D, Martorana A, Cappello F, Barresi E, Di Gangi C, Rodolico V: Carcinosarcoma of monoclonal origin arising in a dermoid cyst of ovary: a case report. BMC Cancer; 2006;6:47
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  • [Title] Carcinosarcoma of monoclonal origin arising in a dermoid cyst of ovary: a case report.
  • BACKGROUND: Transformation of a cystic benign teratoma of the ovary into a "carcinosarcoma" has very rarely been reported and its histogenetic origin is still debated.

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38. den Bakker MA, Ansink AC, Ewing-Graham PC: "Cutaneous-type" angiosarcoma arising in a mature cystic teratoma of the ovary. J Clin Pathol; 2006 Jun;59(6):658-60
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  • [Title] "Cutaneous-type" angiosarcoma arising in a mature cystic teratoma of the ovary.
  • Benign and malignant somatic tumours arising in mature cystic teratomas of the ovary are a rare but recognised phenomenon.
  • An angiosarcoma with "cutaneous" type typical features arising in a dermoid cyst of the ovary is reported.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16731607.001).
  • [ISSN] 0021-9746
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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39. Newsom-Davis T, Poulter D, Gray R, Ameen M, Lindsay I, Papanikolaou K, Butler-Manuel S, Christmas T, Townsend P, Seckl M: Case report: malignant teratoma of the uterine corpus. BMC Cancer; 2009;9:195
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  • [Title] Case report: malignant teratoma of the uterine corpus.
  • BACKGROUND: Teratomas are the commonest germ cell tumours and are most frequently found in the testes and ovary.
  • Initial investigations revealed a benign teratoma of the uterus which was removed.
  • Her symptoms persisted and a recurrent, now malignant, teratoma of the uterine corpus was resected at hysterectomy.
  • [MeSH-major] Teratoma / diagnosis. Uterine Neoplasms / diagnosis

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  • (PMID = 19538751.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 6PLQ3CP4P3 / Etoposide; Q20Q21Q62J / Cisplatin
  • [Other-IDs] NLM/ PMC2709639
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40. Okino H, Koga Y, Tsuneyoshi M, Takeda S: Metachronous mature cystic teratomas in the left ovary and bilateral diaphragm: Report of a case. Surg Today; 2006;36(11):1012-4
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  • [Title] Metachronous mature cystic teratomas in the left ovary and bilateral diaphragm: Report of a case.
  • To our knowledge, only seven cases of pathologically benign mature cystic teratoma originating in the diaphragm have been reported.
  • We report the case of a 45-year-old woman found to have a mature cystic teratoma below the left side of her diaphragm.
  • She had undergone oophorectomy for a huge mature cystic teratoma in the left ovary 34 years earlier, followed 1 year later by excision of a tumor in the right side of the diaphragm.
  • All sections of the pathological specimen showed evidence of a mature cystic teratoma and pathologically resembled the specimens obtained in the previous two operations.
  • Although this tumor might have been a recurrence of the mature cystic teratoma in the left ovary, it is more likely that multicentric teratomatous foci metachronously developed in the gonadal and extragonadal sites.
  • [MeSH-major] Diaphragm / pathology. Muscle Neoplasms / pathology. Neoplasms, Second Primary. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 17072726.001).
  • [ISSN] 0941-1291
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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41. Hascalik S, Celik O, Sarac K, Meydanli MM, Alkan A, Mizrak B: Metabolic changes in pelvic lesions: findings at proton MR spectroscopic imaging. Gynecol Obstet Invest; 2005;60(3):121-7
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  • RESULTS: Spectroscopy analysis of serous, mucinous and undifferentiated carcinoma of the ovary revealed Cho, lactate and lipid signals, but granulosa-theca cell tumor showed only a lipid signal.
  • The Cho signal was obtained from only 3 patients with mature cystic teratoma but none of the other benign ovarian tumors and pelvic abscesses.
  • A lipid signal was detected in 3 patients diagnosed with pelvic abscess and all benign ovarian tumors.
  • One case of endometrioma and 1 case of teratoma did not show any signal.
  • CONCLUSION: MRS demonstrates significant differences in metabolite concentration between benign and malignant ovarian tumors and pelvic abscesses.
  • [MeSH-minor] Abdominal Abscess / metabolism. Abdominal Abscess / pathology. Adult. Aged. Choline / metabolism. Creatine / metabolism. Dermoid Cyst / metabolism. Dermoid Cyst / pathology. Diagnosis, Differential. Endometriosis / metabolism. Endometriosis / pathology. Female. Granular Cell Tumor / metabolism. Granular Cell Tumor / pathology. Humans. Lipid Metabolism. Middle Aged. Neoplasms, Cystic, Mucinous, and Serous / metabolism. Neoplasms, Cystic, Mucinous, and Serous / pathology. Ovarian Neoplasms / metabolism. Ovarian Neoplasms / pathology. Protons. Teratoma / metabolism. Teratoma / pathology

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  • [Copyright] Copyright (c) 2005 S. Karger AG, Basel.
  • (PMID = 15920339.001).
  • [ISSN] 0378-7346
  • [Journal-full-title] Gynecologic and obstetric investigation
  • [ISO-abbreviation] Gynecol. Obstet. Invest.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Protons; MU72812GK0 / Creatine; N91BDP6H0X / Choline
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42. Coronado Martín PJ, Fasero Laiz M, García Santos J, Ramírez Mena M, Vidart Aragón JA: [Overexpression and prognostic value of p53 and HER2/neu proteins in benign ovarian tissue and in ovarian cancer]. Med Clin (Barc); 2007 Jan 13;128(1):1-6
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  • [Title] [Overexpression and prognostic value of p53 and HER2/neu proteins in benign ovarian tissue and in ovarian cancer].
  • [Transliterated title] Grado de expresión y valor pronóstico de las proteínas p53 y HER2/neu en el tejido ovárico benigno y en el cáncer de ovario.
  • PATIENTS AND METHOD: p53 and HER2/neu immunostaining were performed in 198 tissue samples, 124 EOC, 44 benign ovarian tumors and 30 normal ovaries.
  • RESULTS: Neither p53 nor HER2/neu overexpression was seen in the benign ovarian tumors.
  • HER2/neu immunostaining was observed in one normal ovary.
  • [MeSH-major] Cystadenoma, Mucinous / genetics. Cystadenoma, Serous / genetics. Ovarian Neoplasms / genetics. Receptor, ErbB-2 / genetics. Teratoma / genetics. Tumor Suppressor Protein p53 / genetics


43. Fellegara G, Young RH, Kuhn E, Rosai J: Ovarian mature cystic teratoma with florid vascular proliferation and Wagner-Meissner--like corpuscles. Int J Surg Pathol; 2008 Jul;16(3):320-3
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  • [Title] Ovarian mature cystic teratoma with florid vascular proliferation and Wagner-Meissner--like corpuscles.
  • An ovarian mature cystic teratoma featuring florid vascular proliferation and Wagner-Meissner-like corpuscles is presented.
  • [MeSH-major] Mechanoreceptors / pathology. Neovascularization, Pathologic / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18573789.001).
  • [ISSN] 1066-8969
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor
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44. Papadias K, Kairi-Vassilatou E, Kontogiani-Katsaros K, Argeitis J, Kondis-Pafitis A, Greatsas G: Teratomas of the ovary: a clinico-pathological evaluation of 87 patients from one institution during a 10-year period. Eur J Gynaecol Oncol; 2005;26(4):446-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Teratomas of the ovary: a clinico-pathological evaluation of 87 patients from one institution during a 10-year period.
  • AIM: To present the classification and diagnostic problems encountered between teratomas and other ovarian tumors as well as with other benign entities diagnosed and treated in our institution.
  • Fifty-seven cases presented with a histological diagnosis of mature teratoma, biphasic or triphasic type, three cases with monodermal teratoma, ten cases with ovarian neoplasms of mixed type, 15 cases with epidermal cysts, and two cases with benign cysts.
  • [MeSH-major] Ovarian Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Teratoma / diagnosis

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  • (PMID = 16122200.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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45. Korkontzelos I, Stamatopoulos C, Antoniou N, Zagaliki A, Demou A, Bakolas G: Malignant transformation of ovarian mature cystic teratoma in a postmenopausal woman presented as acute abdomen. Arch Gynecol Obstet; 2010 Jan;281(1):177-9
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  • [Title] Malignant transformation of ovarian mature cystic teratoma in a postmenopausal woman presented as acute abdomen.
  • Especially in postmenopausal women, the clinical manifestation of a mature teratoma with undiagnosed malignant transformation as acute abdomen is extremely rare.
  • [MeSH-major] Abdomen, Acute / etiology. Ovarian Neoplasms / complications. Teratoma / complications
  • [MeSH-minor] Carcinoma, Squamous Cell / pathology. Female. Humans. Middle Aged. Ovary / pathology

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  • (PMID = 19424710.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
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46. Tongsong T, Luewan S, Phadungkiatwattana P, Neeyalavira V, Wanapirak C, Khunamornpong S, Sukpan K: Pattern recognition using transabdominal ultrasound to diagnose ovarian mature cystic teratoma. Int J Gynaecol Obstet; 2008 Nov;103(2):99-104
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pattern recognition using transabdominal ultrasound to diagnose ovarian mature cystic teratoma.
  • OBJECTIVE: To determine the validity of sonographic pattern recognition in the diagnosis of mature cystic teratoma.
  • Examinations were performed by the same sonographer to identify benign cystic teratoma.
  • CONCLUSION: Sonographic pattern recognition using transabdominal ultrasound with color extended-flow mapping can accurately diagnose mature cystic teratoma.
  • [MeSH-major] Ovarian Neoplasms / diagnostic imaging. Pattern Recognition, Automated. Teratoma / diagnostic imaging. Ultrasonography, Doppler, Color / methods

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  • (PMID = 18718589.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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47. Mekni A, Bouraoui S, Oueslati B, Kchir N, Bellil K, Haouet S, Zitouna MM: [Mature cystic teratoma of the fallopian tube. A case report]. Tunis Med; 2005 Jan;83(1):48-50
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  • [Title] [Mature cystic teratoma of the fallopian tube. A case report].
  • [Transliterated title] Teratome kystique mature de la trompe. A propos d'une observation.
  • Histologically they are similar to teratoma of the ovary and elsewhere.
  • We describe a mature cystic teratoma of the fallopian tube found incidentally in a 35-year-old woman operated for suspicion of ectopic tubal pregnancy.
  • The feature of benign teratoma of the fallopian tube is discussed.
  • [MeSH-major] Fallopian Tube Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 15881722.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Tunisia
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48. Las Heras F, Pritzker KP, Colgan TJ: Chordoma arising in a mature cystic teratoma of the ovary: a case report. Pathol Res Pract; 2007;203(6):467-71
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  • [Title] Chordoma arising in a mature cystic teratoma of the ovary: a case report.
  • Mature cystic teratoma of the ovary (MCTO) is the most common type of ovarian teratoma and also the most frequent tumor originating from germ cells.
  • Squamous cell carcinoma is the most common malignancy arising in these otherwise benign tumors.
  • [MeSH-major] Cell Differentiation. Cell Transformation, Neoplastic / pathology. Chordoma / diagnosis. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 17418959.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Ki-67 Antigen; 0 / Mucin-1; 0 / S100 Proteins; 0 / TP53 protein, human; 0 / Tumor Suppressor Protein p53; 0 / Vimentin; 68238-35-7 / Keratins
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49. Adams H, Went P, Tolnay M, Sartorius G, Singer G: [Meningothelial meningioma in a mature cystic teratoma of the ovary]. Pathologe; 2007 Jul;28(4):278-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Meningothelial meningioma in a mature cystic teratoma of the ovary].
  • Mature teratomas belong to the group of germ cell tumors of the ovary.
  • They account for 27-44% of all ovarian neoplasms and up to 58% of all benign tumors of the ovary.
  • These tumors can show benign or malignant behavior.
  • We report the case of a meningothelial meningioma, found within a mature teratoma of a 32 year old female.
  • [MeSH-major] Meningeal Neoplasms / pathology. Meningioma / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


50. Gurrera A, Brancato F, Puzzo L, Magro G, Greco P: [Squamous cell carcinoma in situ arising in ovarian mature cystic teratoma]. Pathologica; 2008 Feb;100(1):9-12
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  • [Title] [Squamous cell carcinoma in situ arising in ovarian mature cystic teratoma].
  • [Transliterated title] Carcinoma squamoso in situ insorto su teratoma cistico maturo ovarico.
  • Mature cystic teratoma is a benign neoplasm, but malignant transformation of one component may occur in 2% of cases.
  • Although very different types of carcinomas may be arise from mature cystic teratoma, invasive squamous cell carcinoma is the most frequent type of malignancy found, comprising about 80% of all malignancies arising from dermoid tumours.
  • Although invasive squamous cell carcinoma is relatively frequent, it is surprising that so few cases of squamous cell carcinoma in situ in mature cystic teratoma have been reported.
  • We describe a case of squamous cell carcinoma in mature cystic teratoma without an invasive component.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


51. Wickremasinghe D, Samarasekera DN: A benign teratoma of the ovary fistulating into the rectum. Ceylon Med J; 2010 Dec;55(4):133
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  • [Title] A benign teratoma of the ovary fistulating into the rectum.
  • [MeSH-major] Ovarian Neoplasms / complications. Rectovaginal Fistula / etiology. Teratoma / complications

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  • (PMID = 21341632.001).
  • [ISSN] 0009-0875
  • [Journal-full-title] The Ceylon medical journal
  • [ISO-abbreviation] Ceylon Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Sri Lanka
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52. Yahata T, Kawasaki T, Serikawa T, Suzuki M, Tanaka K: Adenocarcinoma arising from respiratory ciliated epithelium in benign cystic teratoma of the ovary: a case report with analyzes of the CT, MRI, and pathological findings. J Obstet Gynaecol Res; 2008 Jun;34(3):408-12
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  • [Title] Adenocarcinoma arising from respiratory ciliated epithelium in benign cystic teratoma of the ovary: a case report with analyzes of the CT, MRI, and pathological findings.
  • The malignant transformation of mature cystic teratoma is rare, thus occurring in only 1-2% of all cases.
  • The most common malignancy arising in mature cystic teratoma is squamous cell carcinoma.
  • We herein present a patient with an ovarian mature cystic teratoma who demonstrated a malignant transformation to well-differentiated adenocarcinoma.
  • This is the third reported case of adenocarcinoma arising in the respiratory epithelium of an ovarian mature cystic teratoma.
  • [MeSH-major] Adenocarcinoma / diagnosis. Infant. Magnetic Resonance Imaging. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis. Tomography, X-Ray Computed

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  • (PMID = 18588616.001).
  • [ISSN] 1341-8076
  • [Journal-full-title] The journal of obstetrics and gynaecology research
  • [ISO-abbreviation] J. Obstet. Gynaecol. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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53. Ehrlich PF, Teitelbaum DH, Hirschl RB, Rescorla F: Excision of large cystic ovarian tumors: combining minimal invasive surgery techniques and cancer surgery--the best of both worlds. J Pediatr Surg; 2007 May;42(5):890-3
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  • BACKGROUND/PURPOSE: Cystic ovarian lesions can be massive, and preoperative evaluations can often not distinguish benign from malignant tumors.
  • A veress needle decompresses the cyst, and the ovary is delivered out of the peritoneal cavity for either cystectomy or an oophorectomy.
  • Routine surveillance of the omentum, lymph nodes, contralateral ovary, and peritoneal surface is then performed.
  • In a single case, the contralateral ovary had a suspicious lesion, which was biopsied.
  • The pathology included 2 simple cysts, 3 serous cyst adenomas, 3 mature cystic teratomas, and 1 immature teratoma with grade 2 to 3 immature elements.


54. Tate G, Tajiri T, Suzuki T, Mitsuya T: Mutations of the KIT gene and loss of heterozygosity of the PTEN region in a primary malignant melanoma arising from a mature cystic teratoma of the ovary. Cancer Genet Cytogenet; 2009 Apr 1;190(1):15-20
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  • [Title] Mutations of the KIT gene and loss of heterozygosity of the PTEN region in a primary malignant melanoma arising from a mature cystic teratoma of the ovary.
  • A frequent loss of heterozygosity (LOH) at 10q is found in melanoma; however, little is known about the role of PTEN in the pathogenesis of a primary malignant melanoma derived from ovarian mature cystic teratoma, which is an extremely rare melanoma.
  • A LOH analysis revealed hemizygous deletion around and in the PTEN gene not only in the ovarian melanoma but also in a mature cystic teratoma.
  • In the present study, D816H and K558E mutations of the KIT gene were revealed in the melanoma arising from a mature cystic teratoma, but not in a mature cystic teratoma.
  • These results indicate that LOH of the PTEN region is one of the molecular alterations of an ovarian mature cystic teratoma and a KIT mutation is an additional promotional event associated with the oncogenesis of a melanoma arising from an ovarian mature cystic teratoma.
  • [MeSH-major] Loss of Heterozygosity / physiology. Melanoma / genetics. Ovarian Neoplasms / genetics. PTEN Phosphohydrolase / genetics. Proto-Oncogene Proteins c-kit / genetics. Teratoma / genetics


55. Murtaza B, Saeed S, Sharif MA, Malik IB, Mahmood A: Ruptured ovarian teratoma presenting as peritonitis. J Coll Physicians Surg Pak; 2009 Jan;19(1):59-61
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  • [Title] Ruptured ovarian teratoma presenting as peritonitis.
  • An 8 x 6 cm thick walled cyst was found in the left ovary with a minute perforation and purulent fluid coming out of it.
  • Histopathology confirmed benign cystic teratoma of ovary.
  • [MeSH-major] Ovarian Neoplasms / pathology. Peritonitis / etiology. Teratoma / pathology

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  • (PMID = 19149985.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
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56. Ohara Y, Oka K, Pak S, Sando N, Matsumoto T, Teshima S: A case of ovarian mature cystic teratoma presenting as a pedunculated ileal tumor. Pathol Res Pract; 2007;203(1):45-51
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  • [Title] A case of ovarian mature cystic teratoma presenting as a pedunculated ileal tumor.
  • We report on a 34-year-old Japanese woman who presented with a pedunculated ileal tumor and who was finally diagnosed as having a right ovarian mature cystic teratoma penetrating and protruding into the ileum.
  • The colon fiberscope revealed an ileal polyp, diagnosed as mature teratoma.
  • Because of adhesion to the necrotic nodule between the tumor and the right ovary, ileocecal resection and right ovarian cystectomy were performed.
  • The necrotic nodule showed abscess, granulation tissue, foreign body reaction, hairs, normal ileal epithelium, and the ovary with ovums.
  • [MeSH-major] Ileal Neoplasms / pathology. Ileum / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 17101236.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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57. Ding DC, Chen SS: Conservative laparoscopic management of ovarian teratoma torsion in a young woman. J Chin Med Assoc; 2005 Jan;68(1):37-9
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  • [Title] Conservative laparoscopic management of ovarian teratoma torsion in a young woman.
  • Benign cystic tumors, specifically dermoid or mucinous cysts, are the most frequent causes of ovarian torsion.
  • In such situations, conservative management with untwisting of the adnexa, followed by cystectomy to preserve part of the ovary, would be a better option.
  • In this report, we present a case of adnexal torsion due to cystic teratoma.
  • Laparoscopy showed an enlarged, dusky left ovary with torsion.
  • The pathology revealed cystic teratoma of the ovary.
  • [MeSH-major] Ovarian Neoplasms / surgery. Teratoma / surgery

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  • (PMID = 15742862.001).
  • [ISSN] 1726-4901
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China (Republic : 1949- )
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58. Bal J, Gabryś MS, Jałocha I: [The role of selected molecular pathways in the pathogenesis of ovarian teratomas]. Postepy Hig Med Dosw (Online); 2009 May 20;63:242-9
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  • From the research point of view--ovarian teratomas, especially mature ones, are an interesting group of germ-cell tumors of the ovary.
  • Mature ovarian teratomas are benign germ-cell tumors, but in rare cases, especially when they contain solid elements, peritoneal implants may be present which can stimulate malignant processes.

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  • (PMID = 19502685.001).
  • [ISSN] 1732-2693
  • [Journal-full-title] Postepy higieny i medycyny doswiadczalnej (Online)
  • [ISO-abbreviation] Postepy Hig Med Dosw (Online)
  • [Language] POL
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / CCNC protein, human; 0 / Cyclin C; 0 / Cyclins; EC 2.7.11.1 / Oncogene Protein v-akt
  • [Number-of-references] 42
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59. Yamanaka Y, Tateiwa Y, Miyamoto H, Umemoto Y, Takeuchi Y, Katayama K, Hashimoto K: Preoperative diagnosis of malignant transformation in mature cystic teratoma of the ovary. Eur J Gynaecol Oncol; 2005;26(4):391-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preoperative diagnosis of malignant transformation in mature cystic teratoma of the ovary.
  • OBJECTIVE: Malignant transformation of mature cystic teratomas (MCT) of the ovary is extremely rare.
  • There are no established criteria of diagnosis before surgery for carcinoma arising from MCT of the ovary.
  • METHODS: This was a retrospective case series of 278 patients with MCT of the ovary.
  • Mean tumor size and serum SCC level were significantly higher than those of benign MCT.
  • [MeSH-major] Biomarkers, Tumor / blood. Ovarian Neoplasms / diagnosis. Teratoma / diagnosis

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  • (PMID = 16122185.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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60. Galinier P, Carfagna L, Delsol M, Ballouhey Q, Lemasson F, Le Mandat A, Moscovici J, Guitard J, Pienkowski C, Vaysse P: Ovarian torsion. Management and ovarian prognosis: a report of 45 cases. J Pediatr Surg; 2009 Sep;44(9):1759-65
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  • In all the cases, when the ovary was preserved, patients were clinically and ultrasonographically followed up for several months.
  • There was a statistical difference (P = .0003) between the mean of the largest diameter of twisted normal ovary and the mean of the largest diameter of twisted diseased ovary.
  • Underlying pathology was benign in 22 cases and low-grade malignancy in 2 (one grade II immature teratoma and one steroid cell tumor).
  • Although very unlikely, the fear of missing malignancy must incite to proceed with caution and can lead, when the size of the twisted ovary is greater than 75 mm, to prefer laparotomy to laparoscopy.

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  • (PMID = 19735822.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Hong R, Choi DY, Choi SJ, Lim SC: Multicentric infarcted leiomyoadenomatoid tumor: a case report. Int J Clin Exp Pathol; 2009;2(1):99-103
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  • Adenomatoid tumor is a benign, usually small lesion that may be found within the wall of fallopian tubes or beneath the uterine serosa near the uterine cornu.
  • We herein report a very unusual case of infarcted leiomyoadenomatoid tumor of the uterus and ovary in a 24-year-old woman who presented with severe lower abdominal pain and masses in the uterus and right ovary.
  • Pelvic ultrasonography and computed tomography revealed a 5 cm mass in the myometrium and a 4 cm mass in the right ovary.
  • Laparoscopy-assisted transvaginal mass removal was performed under the clinical impression of a uterine leiomyoma and benign ovarian teratoma.

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  • [Cites] Int J Gynecol Pathol. 2007 Jan;26(1):16-20 [17197891.001]
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  • (PMID = 18830386.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Leiomyoadenomatoid tumor / infarction / ovary / uterus
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62. Opris I, Ducrotoy V, Bossut J, Lamy A, Sabourin JC: Oligodendroglioma arising in an ovarian mature cystic teratoma. Int J Gynecol Pathol; 2009 Jul;28(4):367-71
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  • [Title] Oligodendroglioma arising in an ovarian mature cystic teratoma.
  • SUMMARY: We describe a case of oligodendroglioma arising in an ovarian mature cystic teratoma associated with a loss of heterozygosity on the long arm of chromosomes 19 and 10.
  • Ultrasound examination showed a cystic mass arising in the left adnexa suggesting a teratoma.
  • At laparotomy a cystic ovoid mass was found arising from the left adnexa, completely replacing the ovary.
  • These findings were consistent with a low-grade oligodendroglioma arising in a mature ovarian cystic teratoma.
  • [MeSH-major] Neoplasms, Multiple Primary / pathology. Oligodendroglioma / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 19483626.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Poulos C, Cheng L, Zhang S, Gersell DJ, Ulbright TM: Analysis of ovarian teratomas for isochromosome 12p: evidence supporting a dual histogenetic pathway for teratomatous elements. Mod Pathol; 2006 Jun;19(6):766-71
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  • Teratomas are the most common germ cell tumor (GCT) of the ovary and include several types with a range of clinical behavior.
  • As in testicular teratomas, they may be benign, malignant or a component of a mixed GCT.
  • We therefore studied the teratomatous components of six mixed GCTs of the ovary using fluorescence in situ hybridization (FISH) for i(12p).
  • Six mixed GCTs of the ovary occurred in patients 4-33 years of age; all had teratomatous and yolk sac tumor components and three also contained foci of embryonal carcinoma.
  • These findings support that teratoma in mixed ovarian GCTs has a different pathogenesis compared to pure teratoma of the ovary.
  • Furthermore, the findings of i(12p) in both the teratomatous and nonteratomatous components of ovarian mixed GCTs supports that the teratoma derives from other components, similar to the situation in the testis.
  • [MeSH-major] Chromosomes, Human, Pair 12. Gene Amplification. Isochromosomes / genetics. Ovarian Neoplasms / genetics. Teratoma / genetics

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  • (PMID = 16547466.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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64. Hoffman JG, Strickland JL, Yin J: Virilizing ovarian dermoid cyst with leydig cells. J Pediatr Adolesc Gynecol; 2009 Jun;22(3):e39-40
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  • The most frequent germ cell tumor derived from the ovaries is the benign cystic teratoma (dermoid) which accounts for 25% of all ovarian neoplasms.
  • CASE: A 12-year-old female was found to have a large 3 5 x 19 x 12 cm ovarian mature cystic teratoma arising from her right ovary.
  • CONCLUSION: Benign cystic teratomas can produce active hormones, albeit rarely.
  • This is a finding important to consider when ovarian cystectomy is performed for removal of a benign cystic teratoma.

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  • (PMID = 19539195.001).
  • [ISSN] 1873-4332
  • [Journal-full-title] Journal of pediatric and adolescent gynecology
  • [ISO-abbreviation] J Pediatr Adolesc Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 3XMK78S47O / Testosterone
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65. Dede M, Gungor S, Yenen MC, Alanbay I, Duru NK, Haşimi A: CA19-9 may have clinical significance in mature cystic teratomas of the ovary. Int J Gynecol Cancer; 2006 Jan-Feb;16(1):189-93
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  • [Title] CA19-9 may have clinical significance in mature cystic teratomas of the ovary.
  • The objective of this study was to evaluate size, bilaterality, histopathologic origin, and the serum levels of some tumor markers in patients with mature cystic teratomas (MCTs) of the ovary.
  • Since levels of CA19-9 and CA125 may be elevated in both benign and malignant conditions, interpretation of these findings must be made in light of the clinical condition of the patient.
  • [MeSH-major] Biomarkers, Tumor / analysis. CA-19-9 Antigen / genetics. Ovarian Neoplasms / genetics. Ovarian Neoplasms / pathology. Teratoma / genetics. Teratoma / pathology

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  • (PMID = 16445632.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-19-9 Antigen
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66. Ulker V, Gedikbasi A, Numanoglu C, Ozluk Y, Saygi S, Gulkilik A, Salihoglu Y: Mucinous adenocarcinoma arising in ovarian mature cystic teratoma in pregnancy. Arch Gynecol Obstet; 2009 Aug;280(2):287-91
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  • [Title] Mucinous adenocarcinoma arising in ovarian mature cystic teratoma in pregnancy.
  • We report a case of mucinous adenocarcinoma arising from mature cystic teratoma (MCT) of the ovary ascertained incidentally during pregnancy.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Ovarian Neoplasms / pathology. Pregnancy Complications, Neoplastic / pathology. Teratoma / pathology


67. Upadhye V, Gujral S, Maheshwari A, Wuntkal R, Gupta S, Tongaonkar H: Benign cystic teratoma of ovary perforating into small intestine with co-existent typhoid fever. Indian J Gastroenterol; 2005 Sep-Oct;24(5):216-7
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  • [Title] Benign cystic teratoma of ovary perforating into small intestine with co-existent typhoid fever.
  • Intra-peritoneal rupture or perforation into adjacent abdominal viscera is a rare complication of benign cystic teratoma (dermoid cyst) of the ovary.
  • [MeSH-major] Intestinal Perforation / etiology. Ovarian Neoplasms / complications. Teratoma / complications. Typhoid Fever / complications

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  • (PMID = 16361767.001).
  • [ISSN] 0254-8860
  • [Journal-full-title] Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology
  • [ISO-abbreviation] Indian J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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68. Tamai K, Koyama T, Saga T, Kido A, Kataoka M, Umeoka S, Fujii S, Togashi K: MR features of physiologic and benign conditions of the ovary. Eur Radiol; 2006 Dec;16(12):2700-11
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  • [Title] MR features of physiologic and benign conditions of the ovary.
  • In reproductive women, various physiologic conditions can cause morphologic changes of the ovary, resembling pathologic conditions.
  • Benign ovarian diseases can also simulate malignancies.
  • Multicystic lesions that may mimic cystic neoplasms include hyperreactio luteinalis, ovarian hyperstimulation syndrome, and polycystic ovary syndrome.
  • Many benign tumors, including teratoma, Brenner tumor, and sex-cord stromal tumor, frequently show characteristic MRI features.
  • [MeSH-major] Magnetic Resonance Imaging / methods. Ovarian Diseases / diagnosis. Ovary / anatomy & histology

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  • (PMID = 16736136.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 44
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69. Junaid I, Paz R, Salihu HM, Sharma PP, Aliyu ZY: Pseudo-Meig's syndrome with multiple synchronous benign and malignant pelvic tumors. Arch Gynecol Obstet; 2006 Feb;273(5):315-8
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  • [Title] Pseudo-Meig's syndrome with multiple synchronous benign and malignant pelvic tumors.
  • BACKGROUND: Meig's and Pseudo-Meig's syndromes have been reported in association with several malignancies but the concomitant existence of multiple synchronous benign and malignant tumors in association with Pseudo-Meigs' syndrome has not been reported in the published literature.
  • Histological examination confirmed a right ovarian carcinoid tumor embedded within a mature cystic teratoma while the left ovary, fallopian tube and the uterus contained a poorly differentiated adenocarcinoma of the endometrium.
  • CONCLUSION: This is the first case report of Pseudo-Meig's syndrome in association with ovarian carcinoid tumor and multiple synchronous benign and malignant pelvic tumors.
  • [MeSH-minor] Adenocarcinoma / complications. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Asthma / complications. CA-125 Antigen / blood. Carcinoid Tumor / complications. Carcinoid Tumor / pathology. Carcinoid Tumor / surgery. Endometrial Neoplasms / complications. Endometrial Neoplasms / pathology. Endometrial Neoplasms / surgery. Fallopian Tube Neoplasms / complications. Fallopian Tube Neoplasms / pathology. Fallopian Tube Neoplasms / surgery. Female. Humans. Hydrothorax / complications. Middle Aged. Ovarian Neoplasms / complications. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery. Teratoma / complications. Teratoma / pathology. Teratoma / surgery. Uterine Neoplasms / complications. Uterine Neoplasms / pathology. Uterine Neoplasms / surgery

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  • (PMID = 16136360.001).
  • [ISSN] 0932-0067
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / CA-125 Antigen
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70. Aïda AK, Sana BS, Essia S, Carole GB, Ahlem LB, Amel T, Sabah MR: [Malignant degeneration of mature benign teratoma of the ovary: a case report]. Tunis Med; 2005 Nov;83(11):710-3
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  • [Title] [Malignant degeneration of mature benign teratoma of the ovary: a case report].
  • [Transliterated title] Degenerescence maligne des teratomes matures benins de l'ovaire: a propos d'un nouveau cas.
  • Malignant transformation of ovarian mature benign teratomas is an uncommon complication which often occurs in the postmenopausal period.
  • Clinical presentation is similar to that of benign ovarian cysts.
  • The diagnosis is based on the association between a mature teratoma and a non metastatic unitissular, carcinoma or sarcoma.
  • We report the case of a 70-year-old woman who had a squamous cell carcinoma which developed on a teratoma of the ovary, for whom the disease was fatal.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


71. Dhorigol VM, Malur PR, Natu: Primary malignant melanoma of the ovary--a case report. Indian J Pathol Microbiol; 2005 Apr;48(2):213-5
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  • [Title] Primary malignant melanoma of the ovary--a case report.
  • Primary malignant melanoma arising in the ovary is extremely rare.
  • It is known to occur in association with benign cystic teratoma especially in post menopausal women.
  • We report one such case of a primary malignant melanoma of the ovary, occurring in a premenopausal woman, after thorough examination of the patient to rule out a primary elsewhere.

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  • (PMID = 16758670.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 8
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72. Kaspareit J, Friderichs-Gromoll S, Buse E, Habermann G: Spontaneous neoplasms observed in cynomolgus monkeys (Macaca fascicularis) during a 15-year period. Exp Toxicol Pathol; 2007 Nov;59(3-4):163-9
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  • The great majority of neoplasms was benign (23 benign neoplasms versus 10 malignant tumors).
  • Most of the tumors (22) in the cynomolgus monkeys were seen in endocrine organs (adrenal cortical adenoma, adrenal hemangioma, C-cell carcinoma, follicular adenoma), respiratory system (nasal cavity adenoma, pulmonary squamous cell carcinoma, bronchio-alveolar carcinoma, bronchiolar papilloma, chondromatous hamartoma) and female genital system (uterine polyp, uterine adenoma, uterine leiomyoma and teratoma of the ovary).

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  • (PMID = 17869495.001).
  • [ISSN] 0940-2993
  • [Journal-full-title] Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie
  • [ISO-abbreviation] Exp. Toxicol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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73. Allam-Nandyala P, Bui MM, Caracciolo JT, Hakam A: Squamous cell carcinoma and osteosarcoma arising from a dermoid cyst--a case report and review of literature. Int J Clin Exp Pathol; 2010;3(3):313-8
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  • The osteosarcoma and squamous cell carcinoma appear to arise in the background of benign teratomatous environment of a dermoid cyst rather than from "pure" mixed mesodermal tumors of the ovary.
  • [MeSH-minor] Combined Modality Therapy. Diagnosis, Differential. Fatal Outcome. Female. Humans. Middle Aged. Ovary / pathology

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  • (PMID = 20224730.001).
  • [ISSN] 1936-2625
  • [Journal-full-title] International journal of clinical and experimental pathology
  • [ISO-abbreviation] Int J Clin Exp Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 14
  • [Other-IDs] NLM/ PMC2836509
  • [Keywords] NOTNLM ; Malignant dermoid / osteosarcoma / squamous cell carcinoma / teratoma
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74. Bhuiyan ZH, Akhter N, Islam MF, Khan SA, Tawhid MH: Pilimiction. Mymensingh Med J; 2008 Jul;17(2 Suppl):S107-10
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  • Our patient has benign indolent coarse of pilimiction for last 9 years.
  • We did laparotomy in the same sitting. Lt. ovary was almost buried between the leaf of broad ligament and contain a dermoid cyst invading bladder wall to discharge its contents.
  • Histopathologically it appears benign mature cystic teratoma.

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  • (PMID = 18946442.001).
  • [ISSN] 1022-4742
  • [Journal-full-title] Mymensingh medical journal : MMJ
  • [ISO-abbreviation] Mymensingh Med J
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Bangladesh
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75. Spannuth WA, Rocconi RP, Kirby TO, Huh WK, Conner MG: Gamma mode of infiltration associated with poor prognosis in malignant teratoma of the ovary: A case report. Gynecol Oncol; 2005 Jul;98(1):155-7
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  • [Title] Gamma mode of infiltration associated with poor prognosis in malignant teratoma of the ovary: A case report.
  • BACKGROUND: Although mature cystic teratoma is the most common tumor of the ovary, squamous cell carcinoma arising from a mature teratoma is a rare event.
  • CASE: This case involves a 52-year-old woman with stage II squamous cell carcinoma arising in a mature cystic teratoma of the left ovary.
  • CONCLUSION: Squamous cell carcinoma arising from a benign cystic teratoma is a rare event.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 15922442.001).
  • [ISSN] 0090-8258
  • [Journal-full-title] Gynecologic oncology
  • [ISO-abbreviation] Gynecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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76. Haslík L, Mára M, Kuzel D, Zizka Z, Dundr P: [Present occurrence of benign teratoma of ovary and fallopian tube in a patient with adnexal torsion]. Ceska Gynekol; 2006 Jul;71(4):342-4
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  • [Title] [Present occurrence of benign teratoma of ovary and fallopian tube in a patient with adnexal torsion].
  • OBJECTIVE: The authors demonstrate the case of left adnexal torsion caused by 2 benign teratomas in its ovarian and tubal location.
  • CASE: 24-years old woman underwent laparoscopy for several days lasting pain in lower abdomen and ultrasound finding of semicystic mass in the left adnexal region with suspicion of teratoma.
  • The benign teratoma of the left ovary together with a torsion of the left Fallopian tube distended by teratoma was revealed during surgery.
  • Left side salpingectomy and enucleation of the ovarian teratoma has been performed.
  • CONCLUSION: The acute gynaecological torsion event may be caused not only by torsion of uterine fibroid or enlarged tumorous ovary but rarely also by a teratoma of the Fallopian tube.

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  • (PMID = 16956051.001).
  • [ISSN] 1210-7832
  • [Journal-full-title] Ceska gynekologie
  • [ISO-abbreviation] Ceska Gynekol
  • [Language] CZE
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Czech Republic
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77. Zaragoza Vargas PE, Dickter S, Baquera Heredia J, Ortiz Hidalgo C: [Gastric wall in benign cystic teratoma of the ovary]. Ginecol Obstet Mex; 2007 Jan;75(1):43-5
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  • [Title] [Gastric wall in benign cystic teratoma of the ovary].
  • [Transliterated title] Pared gástrica en teratoma quístico benigno de ovario.
  • We present the clinicopathlogical features of an ovarian mature cystic teratoma with a fully developed gastric wall containing an extensive peptic ulcer.
  • There are only two previous reported cases of gastric mucosa with a peptic ulcer in an ovarian teratoma.
  • [MeSH-major] Gastric Mucosa. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 17542268.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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78. Shariat-Torbaghan S, Emami-Aleagha M, Sedighi S, Azadbakht F, Keshvari A, Hajarizadeh B, Rosai J: Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report. Arch Iran Med; 2009 Mar;12(2):186-9
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  • [Title] Squamous cell carcinoma arising in an ovarian mature cystic teratoma: a case report.
  • Malignant transformation in a mature cystic teratoma of the ovary is rare.
  • In the present report, we describe a case of advanced-stage squamous cell carcinoma arising in a mature cystic teratoma.
  • A postmenopausal 63-year-old woman with squamous cell carcinoma arising in a mature cystic teratoma is presented.
  • Histopatholog was compatible with squamous cell carcinoma arising in a mature cystic teratoma.
  • [MeSH-major] Carcinoma, Squamous Cell / ultrasonography. Neoplasms, Multiple Primary / ultrasonography. Ovarian Neoplasms / ultrasonography. Teratoma / ultrasonography

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  • (PMID = 19249893.001).
  • [ISSN] 1029-2977
  • [Journal-full-title] Archives of Iranian medicine
  • [ISO-abbreviation] Arch Iran Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Iran
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 12001-76-2 / Vitamin B Complex; Q20Q21Q62J / Cisplatin; Q573I9DVLP / Leucovorin; U3P01618RT / Fluorouracil
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79. Harms D, Zahn S, Göbel U, Schneider DT: Pathology and molecular biology of teratomas in childhood and adolescence. Klin Padiatr; 2006 Nov-Dec;218(6):296-302
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  • Thus, testicular teratomas of infancy are generally benign.
  • The Kiel Pediatric Tumor Registry includes 541 teratoma specimens, and among these, the most frequent tumor sites (in descending order) are: the sacrococcygeal region (33.8 %), the ovaries (31.2 %) and the testes (10.5 %).
  • [MeSH-major] Ovarian Neoplasms. Registries. Teratoma. Testicular Neoplasms
  • [MeSH-minor] Adolescent. Adult. Age Factors. Child. Chromosome Aberrations. Chromosome Deletion. Cytogenetic Analysis. Endodermal Sinus Tumor / epidemiology. Endodermal Sinus Tumor / pathology. Female. Germany / epidemiology. Heterozygote. Humans. Incidence. Infant. Infant, Newborn. Male. Ovary / pathology. Puberty. Testis / pathology

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  • (PMID = 17080330.001).
  • [ISSN] 0300-8630
  • [Journal-full-title] Klinische Pädiatrie
  • [ISO-abbreviation] Klin Padiatr
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
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80. Wu DH, McMurtrie DG, Hirsch SD, Johnston CM: Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report. J Reprod Med; 2008 Feb;53(2):141-4
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  • [Title] Postmenopausal hyperandrogenism caused by a benign cystic teratoma: a case report.
  • BACKGROUND: Mature, benign cystic teratomas of the ovary are common in reproductive-age women, but they are very rarely associated with androgen production and subsequent development of hirsutism or virilization.
  • We describe a case of postmenopausal hirsutism and hyperandrogenism caused by a mature cystic teratoma as well as the 7 previously reported cases.
  • Pelvic ultrasound showed a complex cystic mass in the left ovary measuring 6.0 x 7.0 x 10 cm, and laboratory evaluations revealed progressively increasing testosterone levels.
  • The patient underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy, with resection of a large, complex mass originating in the left ovary.
  • CONCLUSION: Although rare, ovarian production of androgens resulting in hirsutism or virilization can occur with a hormonally active mature cystic teratoma.
  • [MeSH-major] Hyperandrogenism / etiology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18357809.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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81. Kyung MS, Choi JS, Hong SH, Kim HS: Elevated CA 19-9 levels in mature cystic teratoma of the ovary. Int J Biol Markers; 2009 Jan-Mar;24(1):52-6
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  • [Title] Elevated CA 19-9 levels in mature cystic teratoma of the ovary.
  • The purpose of this study was to evaluate the clinical value of serum tumor markers in patients with ovarian mature cystic teratoma (MCT).
  • We retrospectively evaluated 163 women who underwent surgery for MCT of the ovary between March 2003 and August 2007 and who provided preoperative blood samples for the measurement of CA 19-9 and CA 125.
  • [MeSH-major] Biomarkers, Tumor / blood. CA-19-9 Antigen / blood. Ovarian Neoplasms / blood. Teratoma / blood

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  • (PMID = 19404923.001).
  • [ISSN] 0393-6155
  • [Journal-full-title] The International journal of biological markers
  • [ISO-abbreviation] Int. J. Biol. Markers
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / CA-19-9 Antigen
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82. Robboy SJ, Shaco-Levy R, Peng RY, Snyder MJ, Donahue J, Bentley RC, Bean S, Krigman HR, Roth LM, Young RH: Malignant struma ovarii: an analysis of 88 cases, including 27 with extraovarian spread. Int J Gynecol Pathol; 2009 Sep;28(5):405-22
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  • Adhesions (graded 2 to 4+), peritoneal fluid (> or =1 L) or ovarian serosal rent were worrisome features, occurring in 74% of 27 biologically malignant tumors but only 10% of 61 clinically benign tumors.
  • The size of the strumal component rather than the overall size of the ovarian teratoma also had some predictive value.
  • Eight tumors confined initially to the ovary (stage 1) recurred.

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  • (PMID = 19696610.001).
  • [ISSN] 1538-7151
  • [Journal-full-title] International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
  • [ISO-abbreviation] Int. J. Gynecol. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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83. Güney M, Oral B, Demir F, Ozsoy M, Kapucuoğlu N: Mucinous adenocarcinoma arising from the gastrointestinal epithelium in benign cystic teratoma of the ovary--case report. Eur J Gynaecol Oncol; 2006;27(3):304-6
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  • [Title] Mucinous adenocarcinoma arising from the gastrointestinal epithelium in benign cystic teratoma of the ovary--case report.
  • Benign cystic teratoma of the ovary (BCTO) is the most common ovarian germ cell tumor occurring predominantly in early adulthood.
  • Most benign cystic teratomas with malignant transformations are squamous cell carcinomas with just 6.8% being adenocarcinomas.
  • [MeSH-major] Adenocarcinoma, Mucinous / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 16800267.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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84. Veras E, Deavers MT, Silva EG, Malpica A: Ovarian nonsmall cell neuroendocrine carcinoma: a clinicopathologic and immunohistochemical study of 11 cases. Am J Surg Pathol; 2007 May;31(5):774-82
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  • Nonsmall cell neuroendocrine carcinoma (NSCNEC) of the ovary is a rare and aggressive tumor commonly associated with other surface epithelial and germ cell neoplasms.
  • In 2 cases, the tumor was associated with a mature cystic teratoma; one of them also containing an invasive moderately differentiated adenocarcinoma.
  • A single case was associated with a benign ovarian cyst.
  • The latter case had a dermoid cyst in the contralateral ovary.

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  • (PMID = 17460463.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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85. Yamaguchi K, Mandai M, Fukuhara K, Higuchi T, Hamanishi J, Takakura K, Fujii S: Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period. Oncol Rep; 2008 Mar;19(3):705-11
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  • [Title] Malignant transformation of mature cystic teratoma of the ovary including three cases occurring during follow-up period.
  • The aim of this study was to seek for factors which lead to the early diagnosis of malignant transformation from mature cystic teratoma.
  • Fourteen patients with malignant transformation from mature cystic teratoma of the ovary were analyzed retrospectively for precise clinicopathology and prognosis.
  • On the other hand, in benign cases, a false positive elevation of the serum SCC and CEA was observed in 23.5 and 14.3%, which turned out to be normal in 40 and 52.9% cases in the repeated study, respectively.
  • In conclusion neither imaging analysis nor tumor markers including SCC and CEA accurately diagnose malignant transformation of mature cystic teratoma in its early stage, suggesting that a combination of diagnostic means is important.
  • [MeSH-major] Cell Transformation, Neoplastic. Ovarian Neoplasms / pathology. Teratoma / pathology

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  • (PMID = 18288405.001).
  • [ISSN] 1021-335X
  • [Journal-full-title] Oncology reports
  • [ISO-abbreviation] Oncol. Rep.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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86. Chang HC, Bhatt S, Dogra VS: Pearls and pitfalls in diagnosis of ovarian torsion. Radiographics; 2008 Sep-Oct;28(5):1355-68
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  • Ovarian torsion is usually associated with a cyst or tumor, which is typically benign; the most common is mature cystic teratoma.
  • US features of ovarian torsion include a unilateral enlarged ovary, uniform peripheral cystic structures, a coexistent mass within the affected ovary, free pelvic fluid, lack of arterial or venous flow, and a twisted vascular pedicle.
  • The presence of flow at color Doppler imaging does not allow exclusion of torsion but instead suggests that the ovary may be viable, especially if flow is present centrally.
  • Absence of flow in the twisted vascular pedicle may indicate that the ovary is not viable.
  • Common CT features of ovarian torsion include an enlarged ovary, uterine deviation to the twisted side, smooth wall thickening of the twisted adnexal cystic mass, fallopian tube thickening, peripheral cystic structures, and ascites.
  • Understanding the imaging appearance of ovarian torsion will lead to conservative, ovary-sparing treatment.


87. Sheikh MA, Akhtar J, Batool T, Naqvi R, Taqvi R, Jalil S, Soomro A, Ahmed S, Mirza F: A study of ovarian lesions in pre-menarche girls. J Coll Physicians Surg Pak; 2007 Mar;17(3):162-5
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  • Right ovary was involved in 12 (55%) cases and left in 6 (45%).
  • Six patients had non-tumorous cysts, 3 had benign tumors and 9 were with malignant lesions.
  • There were 2 patients with benign teratoma and one with dermoid cyst.
  • Four patients had malignant teratoma, 4 dysgerminoma and one yolk sac tumor.
  • Benign (tumorous and non-tumorous) and malignant lesions occurred with equal frequency in pre-menarche girls in this study.

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  • (PMID = 17374303.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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