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1. Gkoulioni V, Eleftheriadou A, Yiotakis I, Ferekidou E, Chrisovergis A, Lazaris ACh, Kandiloros D: The efficacy of imiquimod on dysplastic lesions of the oral mucosa: an experimental model. Anticancer Res; 2010 Jul;30(7):2891-6
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  • In one case, a well-differentiated squamous cell carcinoma was converted to a papilloma-like squamous neoplasm with a benign morphology.
  • [MeSH-minor] 9,10-Dimethyl-1,2-benzanthracene. Animals. Antineoplastic Agents / pharmacology. Carcinogens. Carcinoma, Squamous Cell / chemically induced. Carcinoma, Squamous Cell / drug therapy. Carcinoma, Squamous Cell / pathology. Male. Mouth Mucosa / drug effects. Mouth Mucosa / pathology. Rats. Rats, Wistar

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  • Hazardous Substances Data Bank. 7,12-DIMETHYLBENZ(A)ANTHRACENE .
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  • (PMID = 20683029.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Aminoquinolines; 0 / Antineoplastic Agents; 0 / Carcinogens; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; 99011-02-6 / imiquimod
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2. Benbenisty KM, Andea A, Metcalf J, Cook J: Atypical cellular neurothekeoma treated with Mohs micrographic surgery. Dermatol Surg; 2006 Apr;32(4):582-7; discussion 587
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  • BACKGROUND: Atypical cellular neurothekeoma is a rare neoplasm generally regarded as a benign tumor with locally aggressive behavior.
  • RESULTS: The neoplasm was extirpated in a three-stage, five section Mohs surgery procedure.
  • Although most commonly used to address basal and squamous cell carcinoma, it has also been reported as a successful treatment for melanoma and a wide variety of cutaneous malignancies.
  • Debate in the literature is ongoing regarding the true histogenesis of this rare tumor.
  • Because of this tumor's local destructive behavior and propensity to recur with inadequate resection, we recommend Moths micrographic surgery for the treatment of cellular neurothekeomas.

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  • [CommentIn] Dermatol Surg. 2008 Mar;34(3):428 [18248473.001]
  • (PMID = 16681671.001).
  • [ISSN] 1076-0512
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 21
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3. Cai JP, Randall B: HMB-45 expression in a clear cell variant of atypical fibroxanthoma. J Cutan Pathol; 2006 Feb;33(2):186-8
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  • [Title] HMB-45 expression in a clear cell variant of atypical fibroxanthoma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Histiocytoma, Benign Fibrous / metabolism. Histiocytoma, Benign Fibrous / pathology. Neoplasm Proteins / metabolism. Skin Neoplasms / metabolism. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Antigens, Neoplasm. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Melanoma / pathology. Melanoma-Specific Antigens. Sarcoma / pathology

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  • [CommentOn] J Cutan Pathol. 2004 Mar;31(3):284-6 [14984584.001]
  • (PMID = 16420318.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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4. Kosmidis C, Efthimiadis C, Anthimidis G, Karayannopoulou G, Grigoriou M, Vassiliadou K, Berovali E, Fachantidis P, Fahantidis E: Kaposi's sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report. J Med Case Rep; 2008;2:213
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  • [Title] Kaposi's sarcoma of the hand mimicking squamous cell carcinoma in a woman with no evidence of HIV infection: a case report.
  • INTRODUCTION: Kaposi's sarcoma is a vascular neoplasm mainly affecting the skin of the lower extremities.
  • Although it is the most common neoplasm affecting patients with AIDS, sporadic cases in HIV-negative people have been reported.
  • It is a lesion mainly affecting men and its clinical presentation presents a challenge, as it can resemble other benign or malignant skin lesions.
  • The lesion clinically resembled a squamous cell carcinoma.

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  • [Cites] Semin Cancer Biol. 1999 Jun;9(3):151-64 [10343067.001]
  • [Cites] J Am Acad Dermatol. 1999 Sep;41(3 Pt 1):458-9 [10507911.001]
  • [Cites] N Engl J Med. 2000 Apr 6;342(14):1027-38 [10749966.001]
  • [Cites] Epidemiol Infect. 2000 Dec;125(3):671-5 [11218216.001]
  • [Cites] Clin Cancer Res. 2001 Aug;7(8):2263-8 [11489800.001]
  • [Cites] Dermatology. 2004;208(3):255-8 [15118382.001]
  • [Cites] Ann Transplant. 1998;3(1):5-12 [9869891.001]
  • [Cites] Lancet. 1995 Sep 23;346(8978):799-802 [7674745.001]
  • [Cites] Klin Med (Mosk). 1993;71(2):27-30 [8046918.001]
  • [Cites] Acta Oncol. 1996;35(2):193-9 [8639315.001]
  • [Cites] Am J Pathol. 1996 Jun;148(6):2009-16 [8669485.001]
  • [Cites] Verh Dtsch Ges Pathol. 1996;80:318-21 [9065036.001]
  • [Cites] N Engl J Med. 1997 Apr 3;336(14):988-93 [9077377.001]
  • [Cites] Lancet. 1986 Dec 6;2(8519):1309-11 [2878178.001]
  • (PMID = 18565232.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2442120
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5. Thompson LD, Karamurzin Y, Wu ML, Kim JH: Solitary fibrous tumor of the larynx. Head Neck Pathol; 2008 Jun;2(2):67-74
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  • [Title] Solitary fibrous tumor of the larynx.
  • Extrapleural solitary fibrous tumor (SFT) is a localized neoplasm characterized by proliferation of thin-walled vessels and collagen-producing cells and is considered within the "hemangiopericytoma-solitary fibrous tumor" spectrum.
  • A cellular, spindle cell neoplasm was arranged in loose fascicles, associated with heavy collagen fiber deposition.
  • These findings confirmed a diagnosis of extraplural solitary fibrous tumor.
  • CONCLUSIONS: The characteristic histologic pattern of solitary fibrous tumor can be noted in extrapulmonary locations.
  • Development in the larynx is uncommon, but the tumor presents as a polypoid mass with characteristic histologic and immunophenotypic features.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Disease-Free Survival. Humans. Male. Middle Aged. Treatment Outcome

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  • [Cites] Otolaryngol Head Neck Surg. 2005 Jul;133(1):163-5 [16025074.001]
  • [Cites] Arch Pathol Lab Med. 2006 Feb;130(2):213-6 [16454566.001]
  • [Cites] Otolaryngol Head Neck Surg. 2006 May;134(5):880-2 [16647552.001]
  • [Cites] Auris Nasus Larynx. 2007 Sep;34(3):405-8 [17337142.001]
  • [Cites] Mod Pathol. 1999 Nov;12(11):1034-42 [10574600.001]
  • [Cites] Hum Pathol. 1999 Dec;30(12):1464-73 [10667425.001]
  • [Cites] Virchows Arch. 2000 Sep;437(3):248-55 [11037344.001]
  • [Cites] Laryngoscope. 2001 Jul;111(7):1197-202 [11568541.001]
  • [Cites] Am J Surg Pathol. 2002 Feb;26(2):153-70 [11812937.001]
  • [Cites] Cancer. 2002 Feb 15;94(4):1057-68 [11920476.001]
  • [Cites] Am J Surg Pathol. 2003 Jun;27(6):737-49 [12766577.001]
  • [Cites] Laryngoscope. 2003 May;113(5):783-90 [12792311.001]
  • [Cites] Cancer. 1979 Feb;43(2):627-35 [421185.001]
  • [Cites] Am J Surg Pathol. 1989 Aug;13(8):640-58 [2665534.001]
  • [Cites] J Laryngol Otol. 1993 Mar;107(3):252-6 [8509708.001]
  • [Cites] Am J Surg Pathol. 1994 Oct;18(10):992-8 [7522416.001]
  • [Cites] Am J Surg Pathol. 1995 Nov;19(11):1257-66 [7573687.001]
  • [Cites] J Pathol. 1997 Apr;181(4):362-7 [9196431.001]
  • [Cites] Cancer Genet Cytogenet. 1999 Jun;111(2):169-71 [10347558.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2005 Apr;262(4):286-8 [15170575.001]
  • [Cites] Mod Pathol. 1997 Oct;10(10):1028-37 [9346183.001]
  • [Cites] Mod Pathol. 1997 Dec;10(12):1194-200 [9436963.001]
  • [Cites] Histopathology. 1997 Dec;31(6):568-76 [9447390.001]
  • [Cites] J Laryngol Otol. 1998 Mar;112(3):286-9 [9624382.001]
  • (PMID = 20614325.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Other-IDs] NLM/ PMC2807554
  • [Keywords] NOTNLM ; Benign neoplasm / CD34 / Fibroma / Hemangiopericytoma / Immunohistochemistry / Larynx / Mesenchymal tumor / Prognosis / Solitary fibrous tumor / Spindle cell squamous cell carcinoma / Surgery / True vocal cord / bcl-2
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6. Ming W, Hua Q, Tao Z, Zhang D: [Expression and significance of ErbB3 and ErbB4 in patients with laryngeal squamous cell carcinomas]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2007 Aug;21(15):706-8
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  • [Title] [Expression and significance of ErbB3 and ErbB4 in patients with laryngeal squamous cell carcinomas].
  • OBJECTIVE: To explore expression of ErbB3 and ErbB4 genes in laryngeal squamous cell carcinomas and their relation with the biological and clinicopathological parameters.
  • METHOD: Expression of ErbB3 and ErbB4 mRNA in 36 cases of laryngeal carcinomas and normal mucosa of incisal margin, 11 cases of benign proliferative lesions were examined by reverse transcription polymerase chain reaction (RT-PCR).
  • RESULT: In laryngeal carcinomas and benign proliferative lesions, over-expressive positive ratios of ErbB3 were 66.7%, 18.2% respectively (P < 0.01).
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Laryngeal Neoplasms / metabolism. Receptor, Epidermal Growth Factor / metabolism
  • [MeSH-minor] Adult. Aged. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. RNA, Messenger / genetics. Receptor, ErbB-3 / genetics. Receptor, ErbB-3 / metabolism. Receptor, ErbB-4

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  • (PMID = 17969526.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / RNA, Messenger; EC 2.7.10.1 / ERBB4 protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.10.1 / Receptor, ErbB-3; EC 2.7.10.1 / Receptor, ErbB-4
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7. Acevedo-Henao CM, Talagas M, Marianowski R, Pradier O: Recurrent inverted papilloma with intracranial and temporal fossa involvement: A case report and review of the literature. Cancer Radiother; 2010 Jun;14(3):202-5
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  • Inverted papilloma (IP) is a rare nasosinusal benign tumour, with epithelium surface inversion to inside the stroma.
  • As a conclusion, inverted papilloma is a benign tumour with an aggressive course, tendency to recurrence and progression to malignancy.
  • [MeSH-minor] Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Combined Modality Therapy. Disease Progression. Ear, Middle / pathology. Facial Paralysis / etiology. Fatal Outcome. Hearing Loss, Conductive / etiology. Humans. Male. Middle Aged. Nasal Obstruction / etiology. Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / surgery. Petrous Bone / pathology. Petrous Bone / surgery. Radiotherapy, Conformal. Reoperation. Temporal Lobe / pathology. Temporal Lobe / surgery

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  • [Copyright] 2010 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.
  • (PMID = 20418144.001).
  • [ISSN] 1769-6658
  • [Journal-full-title] Cancer radiothérapie : journal de la Société française de radiothérapie oncologique
  • [ISO-abbreviation] Cancer Radiother
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 21
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8. Carlson DL: Necrotizing sialometaplasia: a practical approach to the diagnosis. Arch Pathol Lab Med; 2009 May;133(5):692-8
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  • CONTEXT: Necrotizing sialometaplasia is a benign, self-limited lesion of both major and minor salivary glands, although more commonly the latter.
  • It can represent a diagnostic dilemma and may be mistaken for a malignant neoplasm, such as mucoepidermoid carcinoma, as well as invasive squamous cell carcinoma.
  • [MeSH-minor] Adult. Biomarkers / metabolism. Bulimia / complications. Bulimia / diagnosis. Calcium-Binding Proteins / metabolism. Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Squamous Cell / diagnosis. Diagnosis, Differential. Female. Humans. Male. Membrane Proteins / metabolism. Microfilament Proteins / metabolism. Salivary Gland Neoplasms / diagnosis

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  • [CommentIn] Arch Pathol Lab Med. 2010 Jan;134(1):17 [20073597.001]
  • (PMID = 19415943.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / CKAP4 protein, human; 0 / Calcium-Binding Proteins; 0 / Membrane Proteins; 0 / Microfilament Proteins; 0 / calponin
  • [Number-of-references] 25
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9. Prasad K, Rao SG, Harish K: Giant cell tumor of the temporal bone--a case report. BMC Ear Nose Throat Disord; 2005 Sep 15;5:8
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  • [Title] Giant cell tumor of the temporal bone--a case report.
  • BACKGROUND: Giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull.
  • The petrous portion of the temporal bone forms a rare location for this tumor.
  • CASE PRESENTATION: The authors report a case of a large giant cell tumor involving the petrous and squamous portions of the temporal bone in a 26 year old male patient.
  • Radical excision of the tumor was achieved but facial palsy could not be avoided.
  • CONCLUSION: Radical excision of skull base giant cell tumor may be hazardous but if achieved is the optimal treatment and may be curative.

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  • [Cites] J Oral Maxillofac Surg. 2004 Jan;62(1):116-8 [14733232.001]
  • [Cites] Skeletal Radiol. 2005 Apr;34(4):225-8 [15365782.001]
  • [Cites] J Lab Clin Med. 2004 Oct;144(4):193-200 [15514587.001]
  • [Cites] J Orthop Res. 2005 Jan;23(1):203-9 [15607894.001]
  • [Cites] J Neurosurg. 1983 Aug;59(2):322-7 [6864300.001]
  • [Cites] J Orthop Res. 2000 Jul;18(4):647-54 [11052502.001]
  • [Cites] Neuroradiology. 1999 Apr;41(4):305-7 [10344520.001]
  • [Cites] Int J Oncol. 1999 Feb;14(2):291-300 [9917505.001]
  • [Cites] Histopathology. 1979 Nov;3(6):511-22 [511122.001]
  • [Cites] Surg Neurol. 1985 Jan;23(1):25-30 [3964973.001]
  • [Cites] J Oral Pathol Med. 1999 Feb;28(2):54-8 [9950250.001]
  • [Cites] J Neurosurg. 1994 Jan;80(1):148-51 [8271002.001]
  • [Cites] J Neurosurg. 1987 Jun;66(6):924-8 [3572521.001]
  • [Cites] Cancer. 1992 Sep 1;70(5):1124-32 [1515987.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1988 Aug;66(2):197-208 [3174054.001]
  • [Cites] Surg Neurol. 1978 Mar;9(3):185-8 [635765.001]
  • [Cites] Am J Pathol. 2005 Jul;167(1):117-28 [15972958.001]
  • [Cites] Indian J Cancer. 1991 Dec;28(4):177-80 [1818017.001]
  • [Cites] Surg Neurol. 1986 Jul;26(1):59-62 [3715701.001]
  • [Cites] Clin Orthop Relat Res. 2005 Jun;(435):211-8 [15930941.001]
  • [Cites] Neurosurgery. 1988 Jul;23 (1):120-2 [3173651.001]
  • [Cites] Am J Clin Pathol. 2002 Feb;117(2):210-6 [11863217.001]
  • (PMID = 16162299.001).
  • [ISSN] 1472-6815
  • [Journal-full-title] BMC ear, nose, and throat disorders
  • [ISO-abbreviation] BMC Ear Nose Throat Disord
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1253509
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10. Lesinski-Schiedat A, Hemmanouil I, Sauer-Gönen M, Flemming P, Freihorst I, Kempf HG, Lenarz T: [Malignant transformation of a juvenile papilloma in a 11 year old boy]. Laryngorhinootologie; 2005 Aug;84(8):602-7
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  • BACKGROUND: The juvenile laryngeal papilloma is the most common benign neoplasm in children.
  • Seven months after the first diagnosis of the papilloma a regional metastatic squamous cell carcinoma was found.
  • CONCLUSIONS: The spontaneous malignant transformation of a juvenile papilloma in a squamous cell carcinoma is extremely rare.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Laryngeal Neoplasms / pathology. Papilloma / pathology

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  • (PMID = 16080063.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 9008-11-1 / Interferons
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11. Bratthauer GL, Saenger JS, Strauss BL: Antibodies targeting p63 react specifically in the cytoplasm of breast epithelial cells exhibiting secretory differentiation. Histopathology; 2005 Dec;47(6):611-6
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  • These included seven with benign secretory changes, 10 secretory carcinomas (nine invasive), one microglandular adenosis, three lobular neoplasias, four invasive ductal carcinomas, three clear cell carcinomas, one squamous cell carcinoma and one mucinous carcinoma.
  • [MeSH-major] Antibodies / metabolism. Breast / cytology. Breast / metabolism. Cell Differentiation. Genes, Tumor Suppressor. Phosphoproteins. Trans-Activators
  • [MeSH-minor] Adenocarcinoma, Clear Cell / metabolism. Adenocarcinoma, Clear Cell / pathology. Adenocarcinoma, Mucinous / metabolism. Adenocarcinoma, Mucinous / pathology. Breast Neoplasms / metabolism. Breast Neoplasms / pathology. Carcinoma / chemistry. Carcinoma / pathology. Carcinoma, Intraductal, Noninfiltrating / metabolism. Carcinoma, Intraductal, Noninfiltrating / pathology. Carcinoma, Lobular / metabolism. Carcinoma, Lobular / pathology. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Cytoplasm / metabolism. DNA-Binding Proteins. Epithelial Cells / cytology. Epithelial Cells / metabolism. Female. Fibrocystic Breast Disease / metabolism. Fibrocystic Breast Disease / pathology. Humans. Immunohistochemistry. Neoplasm Invasiveness. Transcription Factors. Tumor Suppressor Proteins

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  • (PMID = 16324199.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antibodies; 0 / DNA-Binding Proteins; 0 / Phosphoproteins; 0 / TP63 protein, human; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Tumor Suppressor Proteins
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12. Taylor JA 3rd, Ristau B, Bonnemaison M, Voznesensky OS, Hegde P, Kuchel GA, Pilbeam CC: Regulation of the prostaglandin pathway during development of invasive bladder cancer in mice. Prostaglandins Other Lipid Mediat; 2009 Jan;88(1-2):36-41
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  • Prostaglandin E(2) (PGE(2)) is reported to play an important role in tumor development.
  • Bladders from BBN-treated mice showed progression from submucosal inflammation (P1) to squamous metaplasia/focal CIS (P2) to poorly differentiated, invasive cancer (P3).
  • Hence, increased COX-2 and decreased PDGH expression occurred throughout tumor development, while mPGES-1, EP2R and EP4R were elevated only before development of invasive cancer.
  • We compared expression of these genes in the malignant human urothelial cell lines, HTB-5 and HT-1376, with expression in a benign urothelial cell line, UROtsa.
  • Neither malignant cell line reproduced the complete in vivo pattern, relative to benign cells, but each showed abnormal basal expression of several of the genes downstream of COX-2, but not COX-2 itself.
  • We conclude that components involved in PGE(2) synthesis and activity are differentially regulated during bladder tumor development and the therapeutic efficacy of targeting the various components may vary with stage of tumor development.

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  • [Cites] Cancer Res. 2000 Oct 15;60(20):5599-602 [11059745.001]
  • [Cites] N Engl J Med. 2000 Jun 29;342(26):1946-52 [10874062.001]
  • [Cites] Urol Res. 2001 Feb;29(1):20-4 [11310210.001]
  • [Cites] J Bone Miner Res. 2002 Aug;17(8):1430-40 [12162497.001]
  • [Cites] J Urol. 2003 Mar;169(3):938-42 [12576817.001]
  • [Cites] Regul Pept. 2003 Jul 15;114(2-3):101-7 [12832097.001]
  • [Cites] J Urol. 2003 Sep;170(3):985-9 [12913755.001]
  • [Cites] Urol Oncol. 2003 Jul-Aug;21(4):266-70 [12954496.001]
  • [Cites] Eur Urol. 2003 Oct;44(4):435-41 [14499677.001]
  • [Cites] J Cell Mol Med. 2003 Jul-Sep;7(3):207-22 [14594546.001]
  • [Cites] Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):591-6 [14688410.001]
  • [Cites] Urology. 2004 Oct;64(4):637-42 [15491687.001]
  • [Cites] Anticancer Res. 1993 Jan-Feb;13(1):33-6 [8476227.001]
  • [Cites] Cancer Res. 1995 Sep 1;55(17):3785-9 [7641194.001]
  • [Cites] Cancer Res. 1997 Apr 1;57(7):1276-80 [9102213.001]
  • [Cites] J Clin Invest. 1997 Sep 15;100(6):1325-9 [9294096.001]
  • [Cites] Cancer Res. 1999 Mar 1;59(5):987-90 [10070951.001]
  • [Cites] Cancer Lett. 2005 Jan 10;217(1):11-6 [15596291.001]
  • [Cites] J Biol Chem. 2005 Feb 4;280(5):3217-23 [15542609.001]
  • [Cites] N Engl J Med. 2005 Mar 17;352(11):1092-102 [15713943.001]
  • [Cites] Clin Cancer Res. 2000 Jun;6(6):2424-30 [10873095.001]
  • [Cites] Urology. 2000 Oct 1;56(4):671-6 [11018637.001]
  • [Cites] Am J Pathol. 2001 Mar;158(3):849-53 [11238034.001]
  • [Cites] J Intern Med. 2005 Aug;258(2):115-23 [16018788.001]
  • [Cites] Nat Rev Cancer. 2005 Sep;5(9):713-25 [16110317.001]
  • [Cites] Gut. 2006 Jan;55(1):115-22 [16118353.001]
  • [Cites] Clin Genitourin Cancer. 2005 Dec;4(3):203-11 [16425990.001]
  • [Cites] Cancer Res. 2006 Mar 15;66(6):3106-13 [16540660.001]
  • [Cites] Prostaglandins Leukot Essent Fatty Acids. 2006 May;74(5):309-15 [16621493.001]
  • [Cites] Cancer Res. 2006 Jul 1;66(13):6649-56 [16818638.001]
  • [Cites] Cancer Res. 2006 Oct 15;66(20):9794-7 [17047037.001]
  • [Cites] J Urol. 2007 Mar;177(3):1163-8 [17296438.001]
  • [Cites] Exp Dermatol. 2007 May;16(5):445-53 [17437488.001]
  • [Cites] Prostaglandins Other Lipid Mediat. 2007 May;83(3):203-8 [17481556.001]
  • [Cites] BMC Cancer. 2007;7:135 [17650334.001]
  • [Cites] Carcinogenesis. 1999 Dec;20(12):2305-10 [10590224.001]
  • [Cites] J Clin Invest. 2000 Mar;105(6):823-32 [10727451.001]
  • [Cites] Oncol Rep. 2006 Feb;15(2):471-7 [16391871.001]
  • (PMID = 18834948.001).
  • [ISSN] 1098-8823
  • [Journal-full-title] Prostaglandins & other lipid mediators
  • [ISO-abbreviation] Prostaglandins Other Lipid Mediat.
  • [Language] ENG
  • [Grant] United States / NIDDK NIH HHS / DK / R01 DK048361; United States / NIDDK NIH HHS / DK / DK048361-08; United States / NIA NIH HHS / AG / R01AG028657; United States / NIDDK NIH HHS / DK / R01 DK048361-08; United States / NIA NIH HHS / AG / AG028657-02; United States / NIDDK NIH HHS / DK / DK048361-13; United States / NIA NIH HHS / AG / R01 AG028657; United States / NIA NIH HHS / AG / R01 AG028657-02; United States / NIDDK NIH HHS / DK / R01DK48361; United States / NIDDK NIH HHS / DK / R01 DK048361-13
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Prostaglandins; 0 / RNA, Messenger
  • [Other-IDs] NLM/ NIHMS84408; NLM/ PMC2615552
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13. Roh JL, Ryu CH, Kim JS, Lee JS, Choi SH, Nam SY, Kim SY: Clinical significance of intrathoracic lesions detected by 18F-fluorodeoxyglucose positron emission tomography in the management of patients with head and neck cancer. Oral Oncol; 2007 Sep;43(8):757-63
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  • Most of the lesions (83%) with abnormal FDG uptake were benign, with thoracic malignancy confirmed in 15 patients (17%).
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / radiography. Carcinoma, Squamous Cell / radionuclide imaging. Carcinoma, Squamous Cell / secondary. Female. Fluorodeoxyglucose F18. Humans. Image Interpretation, Computer-Assisted / methods. Male. Middle Aged. Neoplasm Staging. Radiopharmaceuticals. Retrospective Studies. Risk Factors. Sensitivity and Specificity. Tomography, X-Ray Computed

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  • (PMID = 17112773.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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14. Chaux A, Lezcano C, Cubilla AL, Tamboli P, Ro J, Ayala A: Comparison of subtypes of penile squamous cell carcinoma from high and low incidence geographical regions. Int J Surg Pathol; 2010 Aug;18(4):268-77
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  • [Title] Comparison of subtypes of penile squamous cell carcinoma from high and low incidence geographical regions.
  • There is a worldwide geographical variation in the incidence of penile squamous cell carcinoma (PSCC); some subtypes are HPV-related (warty, basaloid) while others (keratinizing variants) are not.
  • The tendency for typical SCC to mix with verrucous and papillary carcinomas and of the basaloid to preferentially mix with benign condyloma and condylomatous (warty) carcinomas would support the hypothesis of the existence of an etiologically different dual population of penile tumors.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Papillomavirus Infections / pathology. Penile Neoplasms / pathology
  • [MeSH-minor] Carcinoma, Verrucous / epidemiology. Carcinoma, Verrucous / pathology. Carcinoma, Verrucous / virology. Condylomata Acuminata / pathology. Condylomata Acuminata / virology. Humans. Incidence. Male. Neoplasm Invasiveness. Papillomaviridae / isolation & purification. Paraguay / epidemiology. Precancerous Conditions. Retrospective Studies. United States / epidemiology

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  • (PMID = 19578046.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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15. Shi J, Liu H, Wilkerson M, Huang Y, Meschter S, Dupree W, Schuerch C, Lin F: Evaluation of p16INK4a, minichromosome maintenance protein 2, DNA topoisomerase IIalpha, ProEX C, and p16INK4a/ProEX C in cervical squamous intraepithelial lesions. Hum Pathol; 2007 Sep;38(9):1335-44
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  • [Title] Evaluation of p16INK4a, minichromosome maintenance protein 2, DNA topoisomerase IIalpha, ProEX C, and p16INK4a/ProEX C in cervical squamous intraepithelial lesions.
  • p16INK4a has been shown to be overexpressed in nearly all high-grade squamous intraepithelial lesions (HSILs).
  • Other cell-cycle regulators, such as minichromosome maintenance protein 2 (MCM2), DNA topoisomerase IIalpha (TOP IIA), and ProE(X) C (a cocktail of MCM2 and TOP IIA), have also demonstrated some value in identifying squamous intraepithelial lesions.
  • Data on direct comparison of those cell regulatory proteins in the detection of squamous intraepithelial lesions, with a focus on low-grade squamous intraepithelial lesions (LSILs), are limited.
  • We immunohistochemically evaluated the diagnostic value of p16, MCM2, TOP IIA, ProE(X) C, and a cocktail of p16 and ProE(X) C in 62 cervical biopsy specimens, including 14 cases of benign squamous mucosa (group 1), 34 cases of LSILs (group 2), and 14 cases of HSILs (group 3).
  • [MeSH-major] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / pathology. Cell Cycle Proteins / analysis. Cyclin-Dependent Kinase Inhibitor p16 / analysis. DNA Topoisomerases, Type II / analysis. DNA-Binding Proteins / analysis. Nuclear Proteins / analysis. Uterine Cervical Neoplasms / pathology

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  • [CommentIn] Hum Pathol. 2009 Jun;40(6):904-5; author reply 905-6 [19442790.001]
  • (PMID = 17512033.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; EC 3.6.4.12 / MCM2 protein, human; EC 3.6.4.12 / Minichromosome Maintenance Complex Component 2; EC 5.99.1.3 / DNA Topoisomerases, Type II; EC 5.99.1.3 / DNA topoisomerase II alpha
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16. Sandison A: Common head and neck cases in our consultation referrals: diagnostic dilemmas in inverted papilloma. Head Neck Pathol; 2009 Sep;3(3):260-2
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  • Papillomas of the nose and paranasal sinuses comprise three morphologically distinct variants--everted papilloma, inverted papilloma and cylindric cell papilloma in descending order of frequency.
  • The histology of low grade squamous cell carcinoma of the nose may mimic that of inverted papilloma and low grade squamous cell carcinoma may coexist with inverted papilloma and be present in the same biopsy material.
  • Columnar cell papillomas are also associated with an increased risk of malignancy but the rarity of these lesions makes accurate assessment of malignant potential difficult.
  • The most common diagnostic dilemma for pathologists referring cases for second opinion is the recognition of low grade malignancy versus benign inverted papilloma at presentation and in lesions which recur.
  • [MeSH-minor] Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Humans. Neoplasm Recurrence, Local / pathology. Neoplasms, Multiple Primary / pathology. Neoplasms, Second Primary / pathology

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  • [Cites] Semin Diagn Pathol. 1996 May;13(2):113-7 [8734417.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2005 Apr;262(4):263-8 [15258811.001]
  • [Cites] Eur J Surg Oncol. 2005 Oct;31(8):905-11 [16005600.001]
  • [Cites] Acta Otolaryngol. 2006 Feb;126(2):214-8 [16428203.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2006 May;18(4):300-5 [16703747.001]
  • [Cites] Rhinology. 2006 Sep;44(3):211-5 [17020070.001]
  • [Cites] Am J Clin Oncol. 2007 Oct;30(5):560-3 [17921720.001]
  • [Cites] Curr Opin Otolaryngol Head Neck Surg. 2007 Apr;15(2):95-8 [17413409.001]
  • [Cites] J Laryngol Otol. 2007 Sep;121(9):857-64 [17319993.001]
  • [Cites] Hum Pathol. 2008 Mar;39(3):350-8 [18187185.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2008 Aug;265(8):917-22 [18231801.001]
  • [Cites] Am J Otolaryngol. 2008 Jul-Aug;29(4):230-2 [18598832.001]
  • [Cites] Clin Nucl Med. 2007 Apr;32(4):275-8 [17413572.001]
  • (PMID = 20596982.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 13
  • [Other-IDs] NLM/ PMC2811634
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17. Bodtger U, Vilmann P, Clementsen P, Galvis E, Bach K, Skov BG: Clinical impact of endoscopic ultrasound-fine needle aspiration of left adrenal masses in established or suspected lung cancer. J Thorac Oncol; 2009 Dec;4(12):1485-9
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  • Endoscopic ultrasound (EUS) is superior to other imaging procedures in visualizing LAG, but the impact of EUS-fine needle aspiration (FNA) on tumor, node, metastasis (TNM)-staging, treatment, and survival is unknown.
  • RESULTS: EUS-FNA of an enlarged LAG altered the TNM staging in 70% (downstaged: 26 of 28 patients) and treatment in 48% (gained surgery 25%, avoided surgery 5%, surgically verified benign disease 5%, no cancer and no further workup 5%, and no cancer, control computed tomography, and then no further workup 8%).
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adenocarcinoma / ultrasonography. Adult. Aged. Carcinoma, Large Cell / pathology. Carcinoma, Large Cell / surgery. Carcinoma, Large Cell / ultrasonography. Carcinoma, Non-Small-Cell Lung / pathology. Carcinoma, Non-Small-Cell Lung / surgery. Carcinoma, Non-Small-Cell Lung / ultrasonography. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Carcinoma, Squamous Cell / ultrasonography. Endosonography. Female. Follow-Up Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging. Preoperative Care. Prognosis. Retrospective Studies. Small Cell Lung Carcinoma / pathology. Small Cell Lung Carcinoma / surgery. Small Cell Lung Carcinoma / ultrasonography. Treatment Outcome


18. Kim B, Lee HJ, Choi HY, Shin Y, Nam S, Seo G, Son DS, Jo J, Kim J, Lee J, Kim J, Kim K, Lee S: Clinical validity of the lung cancer biomarkers identified by bioinformatics analysis of public expression data. Cancer Res; 2007 Aug 1;67(15):7431-8
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  • We have combined the bioinformatics analysis of the public gene expression data and clinical validation to identify biomarker genes for non-small-cell lung cancer.
  • The microdissected clinical specimens used in the study consisted of three groups: lung tissues from benign diseases and the paired (cancer and pathologic normal) tissues from non-small-cell lung cancer patients.
  • The gene properties of the identified markers, especially their relationship to lung cancer and cell signaling pathway regulation, further suggest their potential value as drug targets as well.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Biomarkers, Tumor / metabolism. Computational Biology. Databases, Genetic. Gene Expression Profiling. Lung Neoplasms / metabolism
  • [MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / metabolism. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Non-Small-Cell Lung / genetics. Carcinoma, Non-Small-Cell Lung / metabolism. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / metabolism. Data Interpretation, Statistical. Female. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. Oligonucleotide Array Sequence Analysis. Reverse Transcriptase Polymerase Chain Reaction. Tumor Cells, Cultured

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  • (PMID = 17671213.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor
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19. Goto T, Maeshima A, Oyamada Y, Kato R: Definitive diagnosis of multiple myeloma from rib specimens resected at thoracotomy in a patient with lung cancer. Interact Cardiovasc Thorac Surg; 2010 Jun;10(6):1051-3
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  • He was diagnosed with squamous cell carcinoma (SCC).
  • Serum immunoelectrophoresis detected IgG-lambda monoclonal protein; therefore, we suspected the coexistence of multiple myeloma, amyloidosis, benign macroglobulinemia, or benign monoclonal gammopathy.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Lung Neoplasms / surgery. Multiple Myeloma / diagnosis. Neoplasms, Multiple Primary. Ribs / pathology. Thoracotomy
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Lymph Node Excision. Male. Middle Aged. Neoplasm Staging. Tomography, X-Ray Computed


20. Gaissert HA, Grillo HC, Shadmehr MB, Wright CD, Gokhale M, Wain JC, Mathisen DJ: Uncommon primary tracheal tumors. Ann Thorac Surg; 2006 Jul;82(1):268-72; discussion 272-3
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  • BACKGROUND: Primary tracheal tumors other than adenoid cystic or squamous cell carcinoma are uncommon and have a heterogeneous histologic appearance.
  • METHODS: A retrospective analysis was performed of uncommon tracheal tumors among 360 primary tracheal tumors seen over 40 years, excluding adenoid cystic and squamous cell carcinoma.
  • RESULTS: Of 90 patients, 34 (38%) had benign tumors and 56 malignant: 11 carcinoid tumors, 14 mucoepidermoid carcinomas, 13 sarcomas, 15 nonsquamous bronchogenic carcinomas, 2 lymphomas, and 1 melanoma.
  • Dyspnea was the most common symptom in benign tumors and hemoptysis in malignant tumors.
  • After resection, survival at 10 years was 94% for benign and 83% for carcinoid tumors, and at 5 years survival was 60% for bronchogenic carcinoma, 100% for mucoepidermoid tumors, and 78% for sarcomas.
  • CONCLUSIONS: Surgical resection of uncommon primary tracheal tumors alleviates airway obstruction, is curative in patients with benign or slow-growing malignant lesions, and prolongs survival in highly malignant lesions.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Bronchi / surgery. Bronchoscopy. Child. Child, Preschool. Combined Modality Therapy. Female. Follow-Up Studies. Hospital Mortality. Humans. Laryngeal Neoplasms / epidemiology. Laryngeal Neoplasms / pathology. Laryngeal Neoplasms / surgery. Laryngectomy. Life Tables. Male. Middle Aged. Neoplasm Metastasis. Neoplasm Recurrence, Local / epidemiology. Postoperative Complications / epidemiology. Radiotherapy, Adjuvant. Reoperation. Retrospective Studies. Survival Analysis

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  • (PMID = 16798228.001).
  • [ISSN] 1552-6259
  • [Journal-full-title] The Annals of thoracic surgery
  • [ISO-abbreviation] Ann. Thorac. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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21. Poetker DM, Toohill RJ, Loehrl TA, Smith TL: Endoscopic management of sinonasal tumors: a preliminary report. Am J Rhinol; 2005 May-Jun;19(3):307-15
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  • For benign tumors, 24 patients were identified with a mean age of 50.7 years, a mean follow-up of 17.5 months, and a recurrence rate of 4.2%.
  • In some cases, adjuvant external procedures may be required based on tumor location.
  • [MeSH-minor] Adenocarcinoma / surgery. Adenoma / surgery. Adult. Aged. Aged, 80 and over. Angiofibroma / surgery. Carcinoma, Adenoid Cystic / surgery. Carcinoma, Squamous Cell / mortality. Carcinoma, Squamous Cell / surgery. Chondrosarcoma / surgery. Esthesioneuroblastoma, Olfactory / surgery. Female. Follow-Up Studies. Hemangiopericytoma / surgery. Humans. Male. Melanoma / surgery. Middle Aged. Nasal Cavity / surgery. Neoplasm Recurrence, Local / epidemiology. Neoplasm Recurrence, Local / therapy. Osteoma / surgery. Papilloma, Inverted / surgery. Retrospective Studies. Survival Rate. Treatment Outcome

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  • (PMID = 16011140.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
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22. Hammes LS, Tekmal RR, Naud P, Edelweiss MI, Kirma N, Valente PT, Syrjänen KJ, Cunha-Filho JS: Up-regulation of VEGF, c-fms and COX-2 expression correlates with severity of cervical cancer precursor (CIN) lesions and invasive disease. Gynecol Oncol; 2008 Sep;110(3):445-51
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  • METHODS: In this study, 26 cases of benign cervix, 28 low-grade cervical intraepithelial neoplasia (CIN; CIN 1), 30 high-grade CIN (CIN 2/3) and 28 squamous cervical carcinomas (SCC) were examined by immunohistochemistry (IHC) and analysis was performed separately for epithelium and stroma.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Cervical Intraepithelial Neoplasia / metabolism. Cyclooxygenase 2 / biosynthesis. Receptor, Macrophage Colony-Stimulating Factor / biosynthesis. Uterine Cervical Neoplasms / metabolism. Vascular Endothelial Growth Factor A / biosynthesis
  • [MeSH-minor] Female. Humans. Immunohistochemistry. Neoplasm Invasiveness. Neoplasm Staging. Neovascularization, Pathologic / genetics. Neovascularization, Pathologic / metabolism. Neovascularization, Pathologic / pathology. Up-Regulation


23. Lipoff JB, Scope A, Busam KJ, Nehal KS: Melanonychia following mohs surgery for recurrent squamous cell carcinoma in situ of the nail bed. J Cutan Med Surg; 2008 Jul-Aug;12(4):194-7
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  • [Title] Melanonychia following mohs surgery for recurrent squamous cell carcinoma in situ of the nail bed.
  • Melanonychia can occur from many causes, including racial predisposition, trauma, drugs, pregnancy, Addison disease, Peutz-Jeghers syndrome, Laugier-Hunziker syndrome, Bowen disease, onychomycosis, benign nail matrix nevi, and melanoma.
  • OBJECTIVE: We present a case of diffuse melanonychia developing several months following Mohs surgery for a human papillomavirus-induced recurrent squamous cell carcinoma in situ of the nail bed.
  • [MeSH-major] Carcinoma, Squamous Cell / surgery. Melanosis / pathology. Melanosis / surgery. Mohs Surgery. Nail Diseases / surgery
  • [MeSH-minor] Adult. Biopsy. Humans. Male. Neoplasm Recurrence, Local

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  • (PMID = 18627701.001).
  • [ISSN] 1203-4754
  • [Journal-full-title] Journal of cutaneous medicine and surgery
  • [ISO-abbreviation] J Cutan Med Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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24. Tatiana K S C, Somers GR, Pope E, Zuker RM: Predisposing factors and outcomes of malignant skin tumors in children. Plast Reconstr Surg; 2010 Aug;126(2):508-14
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  • BACKGROUND: Although benign and metastatic tumors occur in children, primary malignant skin tumors are uncommon in the pediatric population.
  • Diagnosis of malignant melanoma was made in 14 patients, diagnosis of basal cell carcinoma was made in four patients, and diagnosis of squamous cell carcinoma was made in one patient.
  • Gorlin syndrome was an underlying predisposing condition in three patients with basal cell carcinoma.
  • All cases of basal cell carcinoma and squamous cell carcinoma underwent surgical resection and primary closure or skin graft.
  • In accordance with previously published data, malignant melanoma was the most frequent tumor in our study.
  • [MeSH-major] Neoplasm Recurrence, Local / pathology. Sentinel Lymph Node Biopsy / methods. Skin Neoplasms / epidemiology. Skin Neoplasms / surgery. Skin Transplantation / methods
  • [MeSH-minor] Adolescent. Age Distribution. Canada / epidemiology. Carcinoma, Basal Cell / epidemiology. Carcinoma, Basal Cell / pathology. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Causality. Child. Child, Preschool. Cohort Studies. Databases, Factual. Dermatology / methods. Female. Follow-Up Studies. Humans. Immunohistochemistry. Incidence. Male. Melanoma / epidemiology. Melanoma / pathology. Melanoma / surgery. Neoplasm Staging. Sex Distribution. Survival Rate. Treatment Outcome

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  • (PMID = 20375763.001).
  • [ISSN] 1529-4242
  • [Journal-full-title] Plastic and reconstructive surgery
  • [ISO-abbreviation] Plast. Reconstr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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25. Roijer E, de Bruijn HW, Dahlén U, ten Hoor K, Lundin M, Nilsson K, Soderstrom K, Nilsson O: Squamous cell carcinoma antigen isoforms in serum from cervical cancer patients. Tumour Biol; 2006;27(3):142-52
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  • [Title] Squamous cell carcinoma antigen isoforms in serum from cervical cancer patients.
  • Squamous cell carcinoma antigen (SCCA) is a serological marker of squamous cell carcinomas (SCC).
  • Serum samples from patients with benign skin diseases (psoriasis and eczema) were also selected based on elevated SCCA levels.
  • SCCA2 did not show improved tumor specificity as compared to SCCA1.
  • [MeSH-major] Antigens, Neoplasm / blood. Carcinoma, Squamous Cell / diagnosis. Enzyme-Linked Immunosorbent Assay. Serpins / blood. Uterine Cervical Neoplasms / diagnosis


26. Gallego L, Junquera L, Baladrón J, Villarreal P: Oral squamous cell carcinoma associated with symphyseal dental implants: an unusual case report. J Am Dent Assoc; 2008 Aug;139(8):1061-5
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  • [Title] Oral squamous cell carcinoma associated with symphyseal dental implants: an unusual case report.
  • BACKGROUND: The development of squamous cell carcinoma (SCCa) around dental implants is an uncommon pathological manifestation.
  • CLINICAL IMPLICATIONS: This case report demonstrates that recurrent primary malignancy can masquerade as benign peri-implant complications.
  • [MeSH-major] Carcinoma, Squamous Cell / etiology. Dental Implants / adverse effects. Gingival Neoplasms / etiology. Mandibular Neoplasms / etiology. Neoplasm Recurrence, Local / etiology


27. Pedersen JH, Ashraf H, Dirksen A, Bach K, Hansen H, Toennesen P, Thorsen H, Brodersen J, Skov BG, Døssing M, Mortensen J, Richter K, Clementsen P, Seersholm N: The Danish randomized lung cancer CT screening trial--overall design and results of the prevalence round. J Thorac Oncol; 2009 May;4(5):608-14
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  • (1) Nodules smaller than 5 mm and calcified (benign) nodules were tabulated, (2) Noncalcified nodules between 5 and 15 mm were rescanned after 3 months.
  • [MeSH-major] Adenocarcinoma / radiography. Carcinoma, Non-Small-Cell Lung / radiography. Carcinoma, Squamous Cell / radiography. Lung Neoplasms / radiography. Tomography, X-Ray Computed
  • [MeSH-minor] Adult. Aged. Denmark / epidemiology. Early Detection of Cancer. Epidemiologic Research Design. False Positive Reactions. Female. Humans. Male. Mass Screening. Middle Aged. Neoplasm Staging. Prevalence. Prognosis. Sensitivity and Specificity. Smoking / epidemiology

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  • [CommentIn] J Thorac Oncol. 2009 May;4(5):563-4 [19395908.001]
  • (PMID = 19357536.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial
  • [Publication-country] United States
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28. Scheuermann K, Delank KW: [Ackerman's tumor of the larynx and occupational exposure to asbestos]. Laryngorhinootologie; 2007 Aug;86(8):588-91
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  • [Title] [Ackerman's tumor of the larynx and occupational exposure to asbestos].
  • [Transliterated title] Ackerman-Tumor des Larynx und berufliche Asbestexposition.
  • The so-called "Ackerman's tumor" is a neoplasm of uncertain dignity.
  • Aim of this paper is to clarify, whether this is an asbestos-induced tumor of the larynx in accordance with German regulations for occupational diseases.
  • A 43-year old male presented the clinical picture of a stenosing laryngeal tumor.
  • A verrucous neoplasm without a proven malignity in the sense of an Ackerman's tumor was diagnosed through several sequential biopsies.
  • Approximately 2 years later a total laryngectomy was performed, because of a squamous cell carcinoma of the larynx.
  • An Ackerman's tumor is--in accordance with its definition in the German-speaking area--not conclusively malignant, there is no indication of a relation between asbestos and such a tumor in literature, there is no specific benign disorder of the larynx caused by asbestos.
  • This brings us to the conclusion that the Ackerman's tumor of the larynx is no asbestos-induced laryngeal tumor as per German occupational disease regulations.
  • [MeSH-minor] Adult. Aphonia / etiology. Biopsy. Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Disease Progression. Hoarseness / etiology. Humans. Laryngoscopy. Larynx / pathology. Lymph Node Excision. Male. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Respiratory Sounds / etiology

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  • (PMID = 17806001.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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29. Wu JM, Sheth S, Ali SZ: Cytopathologic analysis of paraspinal masses: a study of 59 cases with clinicoradiologic correlation. Diagn Cytopathol; 2005 Sep;33(3):157-61
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  • Of these, 8 (21%) revealed nonneoplastic lesions and 31 (79%) yielded neoplasms: 2 (6%) benign and 29 (94%) malignant.
  • Benign neoplasms were nerve sheath tumors.
  • Metastatic tumors consisted of adenocarcinoma, 9; squamous-cell carcinoma, 3; renal-cell carcinoma, 1; and non-small-cell carcinoma/not otherwise specified (NOS), 9.
  • In instances of radiologic and cytopathologic discrepancy (4 cases, 12%), diagnoses made by FNA reversed the initial radiologic impression of neoplasm to infection, and vice versa.

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16078252.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Miyazaki Y, Ikeda K, Uemura Y, Maehara M, Ohmura N, Sawada S: Non-necrotic invasive squamous cell carcinoma associated with an inverted papilloma: MRI features. Radiat Med; 2006 Feb;24(2):143-6
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  • [Title] Non-necrotic invasive squamous cell carcinoma associated with an inverted papilloma: MRI features.
  • This tumor can be divided into 2 types, those with and those without gross central necrosis.
  • In our case, the tumor did not have any gross central necrosis, and MRI showed convoluted cerebriform patterns.
  • We found that MRI is unable to distinguish malignant and benign regions in a central mass with no gross necrosis, since this lesion does not alter the basic morphological pattern of inverted papilloma.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Magnetic Resonance Imaging. Nose Neoplasms / pathology. Papilloma, Inverted / pathology
  • [MeSH-minor] Fatal Outcome. Humans. Male. Middle Aged. Neoplasm Invasiveness. Tomography, X-Ray Computed


31. Withrow KP, Newman JR, Skipper JB, Gleysteen JP, Magnuson JS, Zinn K, Rosenthal EL: Assessment of bevacizumab conjugated to Cy5.5 for detection of head and neck cancer xenografts. Technol Cancer Res Treat; 2008 Feb;7(1):61-6
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  • To determine the efficacy of fluorescently labeled anti-vascular endothelial growth factor (VEGF) antibody to be used as a cancer specific optical contrast agent to guide surgical resections, we evaluated the sensitivity and specificity of this agent to detect microscopic residual disease in a preclinical model of head and neck squamous cell carcinoma (HNSCC).
  • Using a flank murine model, mice were xenografted with SCC-1 tumor cells and injected with anti-VEGF antibody (bevacizumab) conjugated to an optically active fluorophore (Cy5.5).
  • Samples taken from a non-fluorescing tumor bed (n=15) were found to be histologically benign in 11 of 15.
  • This data supports previous data presented by this group and supports further investigation of fluorescently labeled anti-tumor antibodies to detect disease in the surgical setting.
  • [MeSH-minor] Animals. Antibodies, Monoclonal, Humanized. Bevacizumab. Humans. Male. Mice. Mice, SCID. Neoplasm Transplantation. Transplantation, Heterologous

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  • (PMID = 18198926.001).
  • [ISSN] 1533-0346
  • [Journal-full-title] Technology in cancer research & treatment
  • [ISO-abbreviation] Technol. Cancer Res. Treat.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA13148
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Humanized; 0 / CY5.5 cyanine dye; 0 / Carbocyanines; 0 / Vascular Endothelial Growth Factor A; 2S9ZZM9Q9V / Bevacizumab
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32. Zardo LM, Thuler LC, Zeferino LC, Horta NM, Fonseca Rde C: Performance of the cytologic examination for the diagnosis of endocervical adenocarcinoma in situ: cytologic-histologic correlation in 60 cases. Acta Cytol; 2009 Sep-Oct;53(5):558-64
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  • In 21.7% (13/60) of the patients, the histologic examination revealed cervical intraepithelial neoplasia (CIN) 2/3 and in 5.0% (3/60) squamous invasive carcinoma; in the remaining 5.0% (3/60) the diagnosis pointed to other neoplasms, and 1.7% (1/60) showed exclusively benign squamous cell lesions.
  • [MeSH-major] Adenocarcinoma / pathology. Carcinoma, Squamous Cell / pathology. Cervical Intraepithelial Neoplasia / pathology. Uterine Cervical Neoplasms / pathology. Vaginal Smears
  • [MeSH-minor] Adult. Brazil. Female. Humans. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Sensitivity and Specificity


33. Ridder GJ, Behringer S, Kayser G, Pfeiffer J: [Malignancies arising in sinonasal inverted papillomas]. Laryngorhinootologie; 2008 Nov;87(11):783-90
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  • BACKGROUND: Inverted papillomas are primarily benign neoplasms that occur in the nasal cavity and paranasal sinuses.
  • Comparison was made between the group of patients with inverted papillomas and associated squamous cell carcinomas and the group of patients with benign inverted papillomas.
  • Our data suggest, that the association between carcinoma and inverted papilloma is indirect and that the gradual progression from inverted papilloma to a malignant neoplasm is if at all infrequent.
  • [MeSH-major] Carcinoma, Squamous Cell. Neoplasms, Multiple Primary. Neoplasms, Second Primary. Nose Neoplasms. Papilloma, Inverted. Paranasal Sinus Neoplasms. Sphenoid Sinus
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Maxillary Sinus / pathology. Maxillary Sinus Neoplasms / pathology. Maxillary Sinus Neoplasms / surgery. Middle Aged. Neoplasm Staging. Nose / pathology. Retrospective Studies. Risk Factors. Time Factors

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  • (PMID = 18633858.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Comparative Study; English Abstract; Journal Article
  • [Publication-country] Germany
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34. Bikmaz K, Guerrero CA, Dammers R, Krisht AF, Husain MM: Ectopic recurrence of craniopharyngiomas: case report. Neurosurgery; 2009 Feb;64(2):E382-3; discussion E383
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  • OBJECTIVE: Craniopharyngiomas are benign tumors that originate from squamous cell rests of the embryonal hypophyseal-pharyngeal duct located along the pituitary stalk.
  • After their surgical resection, recurrence usually occurs in the region of the original tumor bed.
  • Her magnetic resonance imaging scan revealed a tumor in the prepontine cistern.
  • INTERVENTION: The first patient underwent operation via a petrosal approach with subtotal resection of the tumor and decompression of the brainstem; this patient had an uneventful postoperative course.
  • The tumor in the second patient was surgically resected through a pterional craniotomy, with an uneventful postoperative course.
  • The third patient's right-sided cerebellopontine angle lesion was microsurgically resected, and the patient was given a single-dose gamma knife for the left-side and residual small right-side tumor.
  • CONCLUSION: Although ectopic recurrence of a craniopharyngioma is very rare, it should always be considered in the differential diagnosis of what appears to be a new tumor in a patient with a history of previously resected craniopharyngiomas.
  • [MeSH-major] Craniopharyngioma / diagnosis. Craniopharyngioma / surgery. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / surgery. Neoplasms, Second Primary / diagnosis. Neoplasms, Second Primary / surgery. Pituitary Neoplasms / diagnosis. Pituitary Neoplasms / surgery

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  • (PMID = 19190442.001).
  • [ISSN] 1524-4040
  • [Journal-full-title] Neurosurgery
  • [ISO-abbreviation] Neurosurgery
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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35. Liu XY, Chen G, Wang Z, Liu FY: Clinical significance of detecting mucin 1 mRNA in diagnosing occult lymph node micrometastasis in esophageal cancer patients. Ai Zheng; 2007 Feb;26(2):194-9
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  • METHODS: The expression of MUC1 mRNA in 366 regional lymph nodes from 63 esophageal squamous cell cancer (ESCC) patients without histopathologically confirmed invasion (pN0), 30 paraesophageal lymph nodes from patients with benign esophageal diseases, and 15 lymph nodes and 15 tumor tissues from ESCC patients with histopathologically proved metastasis (pN1) were detected by reverse transcription-polymerase chain reaction (RT-PCR) to determine micrometastasis.
  • In Logistic regression analysis, lymph node micrometastasis (P<0.05, odds ratio=3.71) and T3 tumor (P<0.05, odds ratio=7.17) were independent prognostic factors.
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Esophageal Neoplasms / metabolism. Lymph Nodes / metabolism. Lymphatic Metastasis / diagnosis. Mucin-1 / biosynthesis
  • [MeSH-minor] Aged. Base Sequence. DNA, Complementary / genetics. DNA, Neoplasm / genetics. Female. Follow-Up Studies. Humans. Male. Middle Aged. Molecular Sequence Data. Neoplasm Staging. Prognosis. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 17298752.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Complementary; 0 / DNA, Neoplasm; 0 / Mucin-1; 0 / RNA, Messenger
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36. Gurrera A, Brancato F, Puzzo L, Magro G, Greco P: [Squamous cell carcinoma in situ arising in ovarian mature cystic teratoma]. Pathologica; 2008 Feb;100(1):9-12
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  • [Title] [Squamous cell carcinoma in situ arising in ovarian mature cystic teratoma].
  • Mature cystic teratoma is a benign neoplasm, but malignant transformation of one component may occur in 2% of cases.
  • Although very different types of carcinomas may be arise from mature cystic teratoma, invasive squamous cell carcinoma is the most frequent type of malignancy found, comprising about 80% of all malignancies arising from dermoid tumours.
  • Although invasive squamous cell carcinoma is relatively frequent, it is surprising that so few cases of squamous cell carcinoma in situ in mature cystic teratoma have been reported.
  • We describe a case of squamous cell carcinoma in mature cystic teratoma without an invasive component.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


37. Unlu HH, Songu M, Ovali GY, Nese N: Inverted papilloma with new bone formation: report of three cases. Am J Rhinol; 2007 Sep-Oct;21(5):607-10
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  • BACKGROUND: An inverted papilloma (IP) is a benign sinonasal tumor of ectodermal origin, which is locally aggressive and destructive, tends to recur if incompletely removed, and has significant malignant potential.
  • We also believe that additional investigations are required to characterize the pathophysiological mechanisms involved in neoplasm-induced osteogenesis.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 17999798.001).
  • [ISSN] 1050-6586
  • [Journal-full-title] American journal of rhinology
  • [ISO-abbreviation] Am J Rhinol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Wilson ML, Elston DM, Tyler WB, Marks VJ, Ferringer T: Dense lymphocytic infiltrates associated with non-melanoma skin cancer in patients with chronic lymphocytic leukemia. Dermatol Online J; 2010;16(3):4
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  • Basal cell carcinomas and squamous cell carcinomas in these patients may have an associated dense peritumoral leukemic infiltrate.
  • This infiltrate can lead to the diagnosis of CLL and may also obscure tumor margins and pose a challenge in the assessment of perineural tumor spread.
  • Immunohistochemical stains are useful in distinguishing leukemic B-cell infiltrates from tumor-reactive T-cell infiltrates.
  • Leukemic cells of CLL are CD20+/CD23+/CD5+/CD43+/CD3-, whereas benign reactive infiltrates are composed of CD20-/CD23-/CD5+/CD43+/CD3+ T-cells.
  • Given the paucity of symptoms in early stages of CLL, a dense lymphoid infiltrate surrounding a cutaneous neoplasm may serve as the first indication of CLL.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Leukemia, Lymphocytic, Chronic, B-Cell / diagnosis. Leukemic Infiltration / diagnosis. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Aged, 80 and over. Antigens, CD20 / analysis. Antigens, CD3 / analysis. Antigens, CD43 / analysis. Antigens, CD5 / analysis. B-Lymphocytes / immunology. B-Lymphocytes / pathology. Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. Male. Receptors, IgE / analysis. T-Lymphocytes / immunology. T-Lymphocytes / pathology

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  • (PMID = 20233561.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD20; 0 / Antigens, CD3; 0 / Antigens, CD43; 0 / Antigens, CD5; 0 / Biomarkers, Tumor; 0 / Receptors, IgE
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39. Badr RE, Walts AE, Chung F, Bose S: BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix. Am J Surg Pathol; 2008 Jun;32(6):899-906
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  • [Title] BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix.
  • This study aims to assess ProEx C expression patterns in benign, atypical, and dysplastic lesions of the cervix and to compare these patterns with p16 and Ki67 expression and with the presence of human papilloma virus DNA as determined by in situ hybridization.
  • ProEx C positivity was limited to the basal layers of the epithelium in 75% of benign cervices.
  • In the remaining 25%, staining extended into the lower half of the epithelium particularly in areas of squamous metaplasia and immature squamous metaplasia.
  • Atypical squamous metaplasia showed varied staining with 24% being positive.
  • To summarize, ProEx C is a reliable marker for high-grade CIN that can be applied to tissue sections to confirm the diagnosis of high-grade CIN and to triage cases of atypical squamous metaplasia.
  • [MeSH-major] Antigens, Neoplasm / analysis. Biomarkers, Tumor / analysis. Carcinoma, Squamous Cell / metabolism. Cell Cycle Proteins / analysis. DNA Topoisomerases, Type II / analysis. DNA-Binding Proteins / analysis. Nuclear Proteins / analysis. Papillomavirus Infections / complications. Uterine Cervical Neoplasms / metabolism

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  • (PMID = 18425044.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Cell Cycle Proteins; 0 / DNA-Binding Proteins; 0 / Nuclear Proteins; EC 3.6.4.12 / MCM2 protein, human; EC 3.6.4.12 / Minichromosome Maintenance Complex Component 2; EC 5.99.1.3 / DNA Topoisomerases, Type II; EC 5.99.1.3 / DNA topoisomerase II alpha
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40. Chao MW, Gibbs P: Squamous cell carcinoma arising in a giant condyloma acuminatum (Buschke-Lowenstein tumour). Asian J Surg; 2005 Jul;28(3):238-40
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  • [Title] Squamous cell carcinoma arising in a giant condyloma acuminatum (Buschke-Lowenstein tumour).
  • Giant condyloma acuminatum (GCA) is a tumour that primarily affects the genital and perianal areas.
  • Despite the histologically benign appearance, it behaves in a malignant fashion, destroying adjacent tissues, and is regarded as an entity intermediate between an ordinary condyloma acuminatum and squamous cell carcinoma.
  • Primary anorectal lesions account for only a small number of GCA cases and, as with squamous cell carcinoma, the human papilloma virus is the causative agent.
  • The hallmark of GCA is the high rate of local recurrence and transformation into squamous cell carcinoma.


41. De Gabory L, Deminière C, Stoll D: [Immunohistochemistry expression of 3 markers (CEA, UEA-I and Ki-67) in nasal inverted papillomas]. Rev Laryngol Otol Rhinol (Bord); 2008;129(3):159-65
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  • [Transliterated title] Expression immunohistochimique de l'ACE, de l'UEA-I et du Ki-67 dans les papillomes inversés naso-sinusiens.
  • OBJECTIVES: Immunohistochemistry evaluation of the expression of degeneration and proliferation markers of the benign form of Schneiderian inverted papillomas in the ORL sphere, in the nondysplastic, dysplastic and degenerated forms.
  • MATERIALS AND METHOD: 44 surgical specimens were analyzed in two groups: A= 33 benign and B= 11 degenerated.
  • A simultaneous bipolar localization belonged to the two groups (nasal, benign and otologic malignant).
  • But, no difference existed between groups A and B, the various sub-groups and the benign specific localizations.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Ki-67 Antigen / analysis. Nose Neoplasms / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology. Plant Lectins / analysis. Sphenoid Sinus / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Child. Diagnosis, Differential. Ear Neoplasms / pathology. Ear Neoplasms / surgery. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Nasal Mucosa / pathology. Nasal Polyps / pathology. Nasal Polyps / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Prognosis. Reference Values

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  • (PMID = 19694158.001).
  • [ISSN] 0035-1334
  • [Journal-full-title] Revue de laryngologie - otologie - rhinologie
  • [ISO-abbreviation] Rev Laryngol Otol Rhinol (Bord)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Ki-67 Antigen; 0 / Plant Lectins; 0 / Ulex europaeus lectins
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42. Li Y, Zhang TM, An YZ, Shi JT, Fu JD, Qiu E: [Clinical study of lacrimal gland tumor involving anterior and middle cranial fossae]. Zhonghua Yi Xue Za Zhi; 2006 Jun 20;86(23):1597-9
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  • [Title] [Clinical study of lacrimal gland tumor involving anterior and middle cranial fossae].
  • OBJECTIVE: To investigate the clinical manifestations of lacrimal gland tumor involving the anterior and middle cranial fossae and the effect of transcranial-orbital approach in treatment of such tumor.
  • METHODS: A retrospective study was conducted on the clinical data of 23 cases lacrimal gland tumor involving the anterior and middle cranial fossae confirmed by radiological examination, including 11 cases of adenoid cystic carcinoma, 6 cases of pleomorphic adenocarcinoma (malignant mixed tumor), 2 cases of adenocarcinoma, 1 case of squamous cell carcinoma, 1 case of ductal carcinoma, 1 case of mucoepidermoid carcinoma, and 1 case of benign mixed tumor, 15 males and 8 females, aged 42.5 (2 - 76), with a case history of 43 months (2 months to 27 years), with the chief complaints of progressive proptosis, disgenesia of the eye ball, and orbit pain, all undergoing transcranial-orbital operation from August 1998 to February. 2006.
  • Recurrence of tumor occurred in 4 cases, and 1 case died from distant metastasis of adenocarcinoma.
  • Adequate orbital apex decompression and exposure of the tumor can result from suitable transcranial-orbital approach.
  • However, complete surgical excision is difficult, and the tumor has a tendency to recur post-operatively.
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Cranial Fossa, Anterior. Cranial Fossa, Middle. Craniotomy. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Invasiveness. Retrospective Studies

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  • (PMID = 16854296.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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43. Yazdani N, Khorsandi-Ashtiani M, Rabbani-Anari M, Bassam A, Kouhi A: Nasal vestibular huge keratoacanthoma: an unusual site. Pak J Biol Sci; 2009 Oct 15;12(20):1385-7
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  • Keratoacanthoma (KA) is a rapidly growing, low-grade neoplasm of pilo-sebaceous and hair follicle units which most often appears on the sun-exposed skin of the middle aged and older persons with multiple or localized occurrence.
  • This tumor is dome-shaped nodule with a central keratinous plug.
  • The etiology of this tumor is not obvious.
  • The histological features of the KA are often very similar to those of a cutaneous squamous cell carcinoma; however, the tumor structure usually provides a basis for their difference.
  • For a clinician and a pathologist it is important to consider a benign lesion like Keratoacanthoma (KA) in the differential diagnosis of ulcerated nasal lesions and pay attention to differ it from Squamous Cell Carcinoma (SCC) which has a different and aggressive management.


44. Tang XJ, Zhou QH, Zhang SF, Liu LX: [Expressions of Nm23, E-cadherin, and beta-catenin in non-small cell lung cancer and their correlations with metastasis and prognosis]. Ai Zheng; 2005 May;24(5):616-21
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  • [Title] [Expressions of Nm23, E-cadherin, and beta-catenin in non-small cell lung cancer and their correlations with metastasis and prognosis].
  • BACKGROUND & OBJECTIVE: Recently, studies showed nm23, E-cadherin, and Catenins play important roles in cellular signal transduction, which enhance complexity of their functions in tumor metastasis and can partly explain the diversity of the results from different studies.
  • This study was to investigate correlations of expressions of nm23, E-cadherin, and beta-Catenin in non-small cell lung cancer (NSCLC) to metastasis and prognosis, and their interrelations.
  • METHODS: Expressions of nm23, E-cadherin, and beta-Catenin in 112 specimens of NSCLC and 30 specimens of benign pulmonary lesion were detected by SP immunohistochemistry.
  • RESULTS: The expressions of nm23, E-cadherin and beta-Catenin were significantly weaker in NSCLC tissues than in adjacent non-cancerous tissues, and benign pulmonary tissues (53.0% vs. 64.8%, and 76.9%, P < 0.01; 53.1% vs. 79.7%, and 83.5%, P < 0.01; and 47.2% vs. 80.6%, and 85.6%, P < 0.01), significantly weaker in NSCLC tissues with lymph node metastasis than in those without metastasis (48.0% vs. 65.0%, P < 0.01; 47.3% vs. 60.5%, P < 0.01; and 41.8% vs. 60.3%, P < 0.01), and significantly weaker in NSCLC tissues of stage III-IV than in those of stage I-II (44.8% vs. 67.2%, P < 0.01; 46.6% vs. 64.3%, P < 0.01; 38.1% vs. 63.1%, P < 0.01).
  • [MeSH-major] Cadherins / metabolism. Carcinoma, Non-Small-Cell Lung / metabolism. Lung Neoplasms / metabolism. Nucleoside-Diphosphate Kinase / metabolism. beta Catenin / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adenocarcinoma / surgery. Adult. Aged. Bronchiectasis / metabolism. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Female. Follow-Up Studies. Humans. Lung / metabolism. Lymphatic Metastasis. Male. Middle Aged. NM23 Nucleoside Diphosphate Kinases. Neoplasm Staging. Prognosis. Survival Rate


45. Ahn Y, Chang H, Lim YS, Hah JH, Kwon TK, Sung MW, Kim KH: Primary tracheal tumors: review of 37 cases. J Thorac Oncol; 2009 May;4(5):635-8
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  • INTRODUCTION: Primary tracheal tumors are rare, and composed of various benign and malignant pathologies.
  • METHODS: From January 1989 through December 2006, 37 patients (14 with benign tumors, 23 with malignant tumors) were treated in a tertiary referral center.
  • RESULTS: Benign tumors comprised of various pathologies.
  • Squamous cell carcinomas (n = 11) and adenoid cystic carcinomas (n = 9) comprised most of the malignant tumors.
  • Five-year overall survival rate was 41.1% for squamous cell carcinoma and 45.7% for adenoid cystic carcinoma and no statistically significant difference (p = 0.673) was observed.
  • CONCLUSION: Papillomas were difficult to manage, however, other benign tumors were successfully treated.
  • [MeSH-major] Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / pathology. Papilloma / pathology. Tracheal Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Child, Preschool. Female. Humans. Infant. Male. Medical Records. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Survival Rate. Young Adult

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  • (PMID = 19357541.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Qin S, Ferdinand AS, Richie JP, O'Leary MP, Mok SC, Liu BC: Chromatofocusing fractionation and two-dimensional difference gel electrophoresis for low abundance serum proteins. Proteomics; 2005 Aug;5(12):3183-92
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  • To facilitate the identification of low abundance proteins, we fractionated serum samples from patients with prostate cancer and patients with benign prostate hyperplasia using anion displacement liquid chromatofocusing chromatography, which separates proteins by a pH gradient and a positively charged column.
  • Three of these proteins, squamous cell carcinoma antigen 1 (SCCA1), calgranulin B, and haptoglobin-related protein, are present in the serum at levels below the classical protein level of mg/mL.
  • [MeSH-minor] Aged. Anions. Antigens, Neoplasm / biosynthesis. Blood Proteins / biosynthesis. Calgranulin B / metabolism. Chemical Fractionation. Chromatography, Liquid. Haptoglobins / biosynthesis. Humans. Hydrogen-Ion Concentration. Image Processing, Computer-Assisted. Male. Mass Spectrometry. Middle Aged. Neoplasm Metastasis. Prostate-Specific Antigen / biosynthesis. Prostatic Intraepithelial Neoplasia / pathology. Serpins / biosynthesis. Serum / chemistry. Time Factors

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  • (PMID = 16035113.001).
  • [ISSN] 1615-9853
  • [Journal-full-title] Proteomics
  • [ISO-abbreviation] Proteomics
  • [Language] eng
  • [Grant] United States / NIDDK NIH HHS / DK / U01 DK 063665
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Anions; 0 / Antigens, Neoplasm; 0 / Blood Proteins; 0 / Calgranulin B; 0 / HPR protein, human; 0 / Haptoglobins; 0 / Serpins; 0 / squamous cell carcinoma-related antigen; EC 3.4.21.77 / Prostate-Specific Antigen
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47. Handisurya A, Rieger A, Bago-Horvath Z, Schellenbacher C, Bankier A, Salat A, Stingl G, Kirnbauer R: Rapid progression of an anal Buschke-Lowenstein tumour into a metastasising squamous cell carcinoma in an HIV-infected patient. Sex Transm Infect; 2009 Aug;85(4):261-3
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  • [Title] Rapid progression of an anal Buschke-Lowenstein tumour into a metastasising squamous cell carcinoma in an HIV-infected patient.
  • BACKGROUND: Buschke-Löwenstein tumour (BLT) of the anogenitalia is a locally invasive, destructively growing verrucous carcinoma that does not metastasise.
  • Histologically BLT resembles benign condylomata acuminata.
  • Nevertheless, the tumour grows relentlessly and may rarely progress into squamous cell cancer (SCC).
  • Six months later, the tumour had progressed into an ulcerated SCC that destroyed the rectum and perineum, with metastases to the inguinal lymph nodes.
  • Whereas highly active antiretroviral therapy (HAART) effectively suppressed HIV replication, radiochemotherapy plus anti-EGFR antibody did not halt tumour progression, and the patient died from tumour-cachexia.
  • [MeSH-major] Anus Neoplasms / pathology. Carcinoma, Squamous Cell / secondary. HIV Infections / complications. Immunocompromised Host
  • [MeSH-minor] Anal Canal / pathology. Anal Canal / virology. Anti-HIV Agents / therapeutic use. Cachexia / etiology. Fatal Outcome. Groin. HIV Seropositivity / drug therapy. Humans. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Invasiveness


48. Tytherleigh MG, Birtle AJ, Cohen CE, Glynne-Jones R, Livingstone J, Gilbert J: Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour. Surgeon; 2006 Dec;4(6):378-83
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  • [Title] Combined surgery and chemoradiation as a treatment for the Buschke-Löwenstein tumour.
  • BACKGROUND: The Buschke-Löwenstein tumour (BLT) or giant condyloma acuminata is a rare disease which affects the anogenital region.
  • Although histologically benign, it behaves in a malignant fashion, infiltrating the surrounding tissues.
  • The morbidity and mortality from this tumour is high, as is the risk of recurrence following treatment.
  • It lies on the continuum between the benign condylomata acuminata and squamous cell carcinoma.
  • Chemoradiation remains the mainstay of treatment for anal cancers but has not been routinely employed in the management of the BLT without squamous cell carcinoma transformation.
  • CONCLUSION: Pre-operative chemoradiation has proved to be useful in management for histologically proven benign BLT
  • [MeSH-minor] Abdominal Neoplasms / secondary. Abdominal Neoplasms / therapy. Adult. Anus Neoplasms / secondary. Anus Neoplasms / therapy. Carcinoma in Situ / pathology. Carcinoma in Situ / therapy. Carcinoma, Squamous Cell / therapy. Chemotherapy, Adjuvant. Cisplatin / administration & dosage. Fatal Outcome. Fluorouracil / administration & dosage. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Radiotherapy, Adjuvant. Rectal Neoplasms / secondary. Rectal Neoplasms / therapy

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  • (PMID = 17152203.001).
  • [ISSN] 1479-666X
  • [Journal-full-title] The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
  • [ISO-abbreviation] Surgeon
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] Q20Q21Q62J / Cisplatin; U3P01618RT / Fluorouracil
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49. Livaoğlu M, Karacal N, Bektaş D, Bahadir O: Reconstruction of full-thickness nasal defect by free anterolateral thigh flap. Acta Otolaryngol; 2009 May;129(5):541-4
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  • All defects resulted from tumor resections.
  • Four patients had a basal cell carcinoma, one an epidermoid carcinoma, and the other patient had recurrent malignant fibrous histiocytoma.
  • [MeSH-minor] Aged. Aged, 80 and over. Carcinoma, Basal Cell / surgery. Carcinoma, Squamous Cell / surgery. Female. Histiocytoma, Benign Fibrous / surgery. Humans. Length of Stay. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Thigh / surgery

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  • (PMID = 18607893.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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50. Zhang X, Chen SB, Chen JX, Wen J, Yang H, Xie MR, Zhang Y, Hu YZ, Lin P: CK19 mRNA expression in the bone marrow of patients with esophageal squamous cell carcinoma and its clinical significance. Dis Esophagus; 2010 Jul;23(5):437-43
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  • [Title] CK19 mRNA expression in the bone marrow of patients with esophageal squamous cell carcinoma and its clinical significance.
  • Expression of CK19 mRNA in the bone marrow of 61 patients with esophageal squamous cell carcinoma (ESCC) and 15 benign pulmonary and esophageal disease patients was assessed via RT-PCR.
  • No CK19 mRNA was detected of the 15 benign pulmonary and esophageal disease patients.

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  • (PMID = 20095997.001).
  • [ISSN] 1442-2050
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Keratin-19; 0 / RNA, Messenger
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51. Hong L, Han Y, Zhang H, Li M, Gong T, Sun L, Wu K, Zhao Q, Fan D: The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma. Ann Surg; 2010 Jun;251(6):1056-63
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  • [Title] The prognostic and chemotherapeutic value of miR-296 in esophageal squamous cell carcinoma.
  • OBJECTIVE: We aimed first to investigate the expression pattern of miRNAs in esophageal squamous cell cancer and then compared it with those of adjacent benign esophageal tissues.
  • SUMMARY BACKGROUND DATA: Although esophageal squamous cell carcinoma was of high incidence in China, the pathogenic mechanism remained largely unknown.
  • The expression of miR-296 was found increasingly up-regulated in esophagitis tissues, esophageal carcinoma in situ, and esophageal squamous cell cancer tissues.
  • [MeSH-major] Carcinoma, Squamous Cell / genetics. Esophageal Neoplasms / genetics. MicroRNAs / physiology
  • [MeSH-minor] Adenocarcinoma / genetics. Adenocarcinoma / mortality. Adenocarcinoma / pathology. Animals. Apoptosis. Biomarkers, Tumor / analysis. Cell Proliferation. Down-Regulation. Drug Resistance, Neoplasm. Genes, cdc. Mice. Mice, Nude. Microarray Analysis. Prognosis. Survival Rate. Tumor Cells, Cultured


52. Sivakumar S: Pilomatrixoma as a diagnostic pitfall in fine needle aspiration cytology: a case report. Acta Cytol; 2007 Jul-Aug;51(4):583-5
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  • BACKGROUND: Pilomatrixoma (pilomatrixoma, calcifying epithelioma of Malherbe) is a relatively uncommon, benign neoplasm arising from the skin adnexa.
  • The tumor can cause diagnostic difficulty not only for the clinician but also for the cytologist.
  • Three preliminary differential diagnoses were offered: mucoepidermoid carcinoma of the submandibular salivary gland, squamous cell carcinomatous deposit in a submandibular lymph node and calcifying odontogenic tumor.
  • No primary site of squamous cell carcinoma could be identified.
  • CONCLUSION: The cytologic presentation of pilomatrixoma of the right submandibular region can masquerade as that of a malignant tumor, in this case mucoepidermoid carcinoma, squamous cell carcinoma or odontogenic tumor.
  • [MeSH-minor] Biopsy, Fine-Needle. Cell Nucleus / pathology. Epithelial Cells / pathology. Female. Humans. Middle Aged

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  • (PMID = 17718128.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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53. Shanks JH, Iczkowski KA: Divergent differentiation in urothelial carcinoma and other bladder cancer subtypes with selected mimics. Histopathology; 2009 Jun;54(7):885-900
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  • A variety of unusual architectural patterns of urothelial carcinoma, such as the nested, microcystic and inverted variants, can be mistaken for reactive processes or benign tumours.
  • Others such as the micropapillary, plasmacytoid and discohesive variants, can mimic metastatic tumour from other sites.
  • In addition, urothelial carcinoma has a propensity to demonstrate divergent differentiation with glandular, squamous, small cell neuroendocrine, lymphoepithelioma-like, sarcomatoid or other elements.
  • Pure squamous carcinoma or adenocarcinoma (the latter in particular) can be difficult to distinguish from contiguous or metastatic spread.
  • Sarcomatoid carcinoma and its differential diagnosis with other spindle cell lesions of urinary tract will be covered in a separate review.
  • [MeSH-minor] Adenocarcinoma, Clear Cell / diagnosis. Adenocarcinoma, Clear Cell / pathology. Adenoma / diagnosis. Adenoma / pathology. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Carcinoma, Transitional Cell / diagnosis. Carcinoma, Transitional Cell / pathology. Cell Differentiation. Cystitis / diagnosis. Cystitis / pathology. Diagnosis, Differential. Giant Cell Tumors / diagnosis. Giant Cell Tumors / pathology. Humans. Neoplasm Metastasis / diagnosis. Neoplasm Metastasis / pathology. Neoplasms, Squamous Cell / diagnosis. Neoplasms, Squamous Cell / pathology. Neuroendocrine Tumors / diagnosis. Neuroendocrine Tumors / pathology. Radiation Injuries / diagnosis. Radiation Injuries / pathology. Urothelium / pathology

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  • (PMID = 19178589.001).
  • [ISSN] 1365-2559
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 152
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54. Furák J, Bács E, Grochulski R, Wolfárd A, Szoke T, Troján I, Csernay E, Lázár G: [Lobectomy performed through a video-assisted mini thoracotomy, as a new technique in our clinical practice]. Magy Seb; 2008 Feb;61(1):29-32
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  • The indications for surgery were the following: benign lesions in three cases, T1N0 squamous lung cancers proved by cytology in six patients, and another case, when the CT suggested - but cytologically not proved - T1N0 lung cancer.
  • The three benign lesions were hamartochondromas.
  • The final histology revealed four T1N0 and two T2N2 stage squamous cell lung cancers, while one T1N2 small cell lung cancer was also found.
  • [MeSH-minor] Aged. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Chondroma / surgery. Female. Hamartoma / surgery. Humans. Lung Neoplasms / pathology. Lung Neoplasms / surgery. Male. Middle Aged. Neoplasm Staging. Retrospective Studies

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  • (PMID = 18296282.001).
  • [ISSN] 0025-0295
  • [Journal-full-title] Magyar sebészet
  • [ISO-abbreviation] Magy Seb
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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55. Li X, Qiao Z, Long X, Wei J, Cheng Y: Serum concentration of AMDL DR-70 for the diagnosis and prognosis of carcinoma of the tongue. Br J Oral Maxillofac Surg; 2005 Dec;43(6):513-5
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  • The aim of this study was to discover the clinical value of the tumour marker AMDL DR-70 in a group of patients with cancer of the tongue.
  • Serum concentrations of AMDL DR-70 were estimated by enzyme linked immuno-sorbent assay in 52 patients with carcinoma of the tongue and compared with 40 controls and 42 patients with benign lesions in the tongue.
  • Thirty-nine patients with carcinoma of the tongue had results above 6 mg/L (75%), compared with 3/40 (7%) in healthy controls and 4/42 (10%) in those with benign tumours.
  • [MeSH-major] Biomarkers, Tumor / analysis. Biomarkers, Tumor / blood. Carcinoma, Squamous Cell / diagnosis. Fibrin Fibrinogen Degradation Products / analysis. Fibrinogen / analysis. Tongue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Female. Fibroma / blood. Follow-Up Studies. Hemangioma / blood. Humans. Male. Middle Aged. Neoplasm Staging. Neurofibroma / blood. Prognosis. Reagent Kits, Diagnostic. Sensitivity and Specificity. Survival Rate

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  • (PMID = 16188352.001).
  • [ISSN] 0266-4356
  • [Journal-full-title] The British journal of oral & maxillofacial surgery
  • [ISO-abbreviation] Br J Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Fibrin Fibrinogen Degradation Products; 0 / Reagent Kits, Diagnostic; 9001-32-5 / Fibrinogen
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56. Tatomirovic Z, Skuletic V, Bokun R, Trimcev J, Radic O, Cerovic S, Strbac M, Zolotarevski L, Tukic Lj, Stamatovic D, Tarabar O: Fine needle aspiration cytology in the diagnosis of head and neck masses: accuracy and diagnostic problems. J BUON; 2009 Oct-Dec;14(4):653-9
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  • The overall accuracy rate of FNA cytology, whether malignant or benign, was 91.89%, while the diagnostic accuracy for the exact type of tumor was 87.16%.
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / secondary. Biopsy, Fine-Needle. Biopsy, Needle. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / secondary. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. Cytological Techniques. Diagnosis, Differential. Diagnostic Errors. Humans. Neoplasm Staging. Prognosis. Sensitivity and Specificity

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  • (PMID = 20148458.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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57. Mistry R, Wademan B, Avery G, Tan ST: A case of misdiagnosed squamous cell carcinoma due to alternative medical misadventure--time for tightening regulation? N Z Med J; 2010 Apr 9;123(1312):61-7
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  • [Title] A case of misdiagnosed squamous cell carcinoma due to alternative medical misadventure--time for tightening regulation?
  • We present a patient with locally advanced squamous cell carcinoma that had grown significantly during 16 months of intensive alternative therapy.
  • The alternative medicine practitioner allegedly repeatedly reassured the patient that her condition was benign and advised against seeking conventional medical treatment.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Complementary Therapies / legislation & jurisprudence. Diagnostic Errors. Skin Neoplasms / diagnosis
  • [MeSH-minor] Aged. Anemia, Macrocytic / diagnosis. Delayed Diagnosis. Dura Mater / pathology. Female. Hemoglobins / analysis. Humans. Leukocyte Count. Neoplasm Invasiveness. New Zealand. Radiotherapy, Adjuvant. Scalp / pathology. Scalp / surgery. Skin Ulcer / microbiology. Skin Ulcer / pathology. Skull / pathology


58. Cai Z, Zhou Y, Lei T, Chiu JF, He QY: Mammary serine protease inhibitor inhibits epithelial growth factor-induced epithelial-mesenchymal transition of esophageal carcinoma cells. Cancer; 2009 Jan 1;115(1):36-48
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  • BACKGROUND: By using proteomic technology, the authors previously observed the substantial down-regulation of mammary serine protease inhibitor (maspin) in esophageal squamous cell carcinoma and metastases.
  • In the current study, they examined the effects of maspin re-expression in a maspin-null esophageal cancer cell line EC109 and also investigated the underlying mechanism.
  • METHODS: A cell line with stable maspin expression was established.
  • The effects of maspin reintroduction on EGF-induced EMT and cell growth characteristics were evaluated.
  • RESULTS: The introduction of maspin into EC109 cells was able to inhibit EGF-induced EMT and altered cell growth characteristics, including the serum dependence, proliferative response to EGF stimulation, and colony formation ability in soft agar, indicating a conversion from a malignant phenotype to a benign phenotype.
  • This finding provides additional evidence of the tumor metastasis-suppressive activity of maspin and may indicate a new direction for future studies of the mechanism of maspin.
  • [MeSH-minor] Cell Differentiation. Cell Line, Tumor. Epidermal Growth Factor / pharmacology. Epithelial Cells. Esophageal Neoplasms. Humans. Neoplasm Metastasis / prevention & control. Transfection

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  • [Copyright] Copyright (c) 2008 American Cancer Society.
  • (PMID = 19090015.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / SERPIN-B5; 0 / Serine Proteinase Inhibitors; 0 / Serpins; 62229-50-9 / Epidermal Growth Factor
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59. National Toxicology Program: Toxicology and carcinogenesis studies of isoeugenol (CAS No. 97-54-1) in F344/N rats and B6C3F1 mice (gavage studies). Natl Toxicol Program Tech Rep Ser; 2010 Sep;(551):1-178
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  • Two male rats in the 300 mg/kg group had rare benign or malignant thymomas, while two other males in this group had rare mammary gland carcinomas.
  • Incidences of clear cell focus were significantly increased in 75 and 150 mg/kg male mice.
  • There was a significant positive trend in the incidences of histiocytic sarcoma in females, and this neoplasm occurred in multiple tissues.
  • Incidences of forestomach squamous hyperplasia, inflammation, and ulceration (males only) increased with exposure and were significant in the 300 mg/kg groups.

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  • (PMID = 21372857.001).
  • [ISSN] 0888-8051
  • [Journal-full-title] National Toxicology Program technical report series
  • [ISO-abbreviation] Natl Toxicol Program Tech Rep Ser
  • [Language] eng
  • [Publication-type] Journal Article; Technical Report
  • [Publication-country] United States
  • [Chemical-registry-number] 3T8H1794QW / Eugenol; 97-54-1 / isoeugenol
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60. Vandecaveye V, De Keyzer F, Hermans R: Diffusion-weighted magnetic resonance imaging in neck lymph adenopathy. Cancer Imaging; 2008;8:173-80
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  • In patients with head and neck squamous cell carcinoma (SCC), nodal metastases are an adverse prognostic factor compromising long term patient survival.
  • Next to evaluation of the primary tumour, both modalities facilitate detection of non-palpable lymph nodes (LN).
  • However, both modalities rely on size-related and morphological criteria to differentiate between benign and malignant lymph nodes, decreasing the sensitivity for detection of small metastases.
  • [MeSH-major] Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. Diffusion Magnetic Resonance Imaging / methods. Echo-Planar Imaging / methods. Head and Neck Neoplasms / diagnosis. Lymph Nodes / pathology. Lymphatic Diseases / pathology
  • [MeSH-minor] Biopsy, Needle. Chemotherapy, Adjuvant. Combined Modality Therapy. Female. Follow-Up Studies. Humans. Immunohistochemistry. Lymphatic Metastasis. Male. Neck / pathology. Neoplasm Staging. Postoperative Care / methods. Preoperative Care / methods. Radiotherapy, Adjuvant. Sensitivity and Specificity. Surgical Procedures, Operative / methods. Survival Rate. Treatment Outcome

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  • [Cites] Radiother Oncol. 2004 Aug;72(2):119-27 [15297131.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Apr 1;58(5):1418-23 [15050318.001]
  • [Cites] Radiology. 1990 Jun;175(3):607-10 [2188292.001]
  • [Cites] Radiology. 2005 Mar;234(3):756-64 [15734932.001]
  • [Cites] Radiographics. 2005 Jul-Aug;25(4):913-30 [16009815.001]
  • [Cites] BMC Cancer. 2006;6:28 [16448551.001]
  • [Cites] AJR Am J Roentgenol. 2006 Mar;186(3):749-57 [16498102.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):733-8 [16751061.001]
  • [Cites] Neoplasia. 2006 Apr;8(4):259-67 [16756718.001]
  • [Cites] Eur Radiol. 2006 Jul;16(7):1468-77 [16557366.001]
  • [Cites] Head Neck. 2007 Jan;29(1):3-11 [17103411.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Mar 15;67(4):960-71 [17141979.001]
  • [Cites] AJR Am J Roentgenol. 2007 Jun;188(6):1622-35 [17515386.001]
  • [Cites] AJNR Am J Neuroradiol. 2007 Jun-Jul;28(6):1146-52 [17569975.001]
  • [Cites] Radiology. 2007 Dec;245(3):806-13 [17911539.001]
  • [Cites] J Thorac Cardiovasc Surg. 2008 Apr;135(4):816-22 [18374761.001]
  • [Cites] Radiology. 2001 Sep;220(3):621-30 [11526259.001]
  • [Cites] Radiology. 2002 Jan;222(1):239-44 [11756732.001]
  • [Cites] Eur Radiol. 2002 Apr;12(4):727-38 [11960218.001]
  • [Cites] Eur Radiol. 2002 May;12(5):1104-13 [11976854.001]
  • [Cites] Ann Otol Rhinol Laryngol. 2002 May;111(5 Pt 1):447-54 [12018330.001]
  • [Cites] Eur J Radiol. 2003 Mar;45(3):208-13 [12595105.001]
  • [Cites] Eur J Radiol. 2003 Mar;45(3):214-22 [12595106.001]
  • [Cites] AJNR Am J Neuroradiol. 2003 Sep;24(8):1627-34 [13679283.001]
  • [Cites] Radiology. 2004 Mar;230(3):720-6 [14990838.001]
  • [Cites] Head Neck. 2004 Oct;26(10):890-6 [15390197.001]
  • (PMID = 18824423.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] England
  • [Number-of-references] 27
  • [Other-IDs] NLM/ PMC2556503
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61. Siar CH, Nakano K, Ng KH, Tomida M, Nagatsuka H, Kawakami T: Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1. Eur J Med Res; 2010 Apr 8;15(4):180-4
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  • [Title] Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.
  • BACKGROUND: Squamous odontogenic tumor (SOT) is a rare benign odontogenic epithelial neoplasm.
  • Although Notch receptors and ligands have been shown to play a role in cell fate decisions in ameloblastomas, the role of these cell signaling molecules in SOT is unknown.
  • Histo?pathological examination revealed a solid, locally-infiltrative neoplasm composed of bland-looking squamatoid islands scattered in a mature fibrous connective tissue stroma and the diagnosis was SOT.
  • [MeSH-major] Calcium-Binding Proteins / metabolism. Intercellular Signaling Peptides and Proteins / metabolism. Mandibular Neoplasms / genetics. Membrane Proteins / metabolism. Odontogenic Tumor, Squamous / genetics. Proto-Oncogene Proteins / metabolism. Receptor, Notch1 / metabolism. Receptors, Notch / metabolism

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  • [Cites] Clin Cancer Res. 2006 Feb 15;12(4):1074-9 [16489059.001]
  • [Cites] Blood. 2006 Mar 15;107(6):2223-33 [16291593.001]
  • [Cites] J Oral Maxillofac Surg. 2006 Aug;64(8):1325 [16860239.001]
  • [Cites] J Oral Maxillofac Surg. 2007 Jun;65(6):1227-31 [17517311.001]
  • [Cites] Int J Oral Maxillofac Surg. 2007 Sep;36(9):864-6 [17509831.001]
  • [Cites] J Oral Pathol Med. 2008 Apr;37(4):228-34 [18221321.001]
  • [Cites] Arch Oral Biol. 2005 Feb;50(2):137-40 [15721140.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1975 Nov;40(5):616-30 [1059063.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1989 Jan;67(1):63-7 [2463509.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1989 Aug;68(2):175-81 [2674829.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1993 Jun;75(6):733-8 [8515987.001]
  • [Cites] Science. 1999 Apr 30;284(5415):770-6 [10221902.001]
  • [Cites] Eur J Med Res. 2008 Oct 27;13(10):476-80 [19008176.001]
  • (PMID = 20554499.001).
  • [ISSN] 0949-2321
  • [Journal-full-title] European journal of medical research
  • [ISO-abbreviation] Eur. J. Med. Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Calcium-Binding Proteins; 0 / Intercellular Signaling Peptides and Proteins; 0 / Intracellular Signaling Peptides and Proteins; 0 / Membrane Proteins; 0 / NOTCH1 protein, human; 0 / NOTCH3 protein, human; 0 / NOTCH4 protein, human; 0 / Proto-Oncogene Proteins; 0 / Receptor, Notch1; 0 / Receptors, Notch; 0 / delta protein; 134324-36-0 / Serrate proteins
  • [Other-IDs] NLM/ PMC3401003
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62. Kazakov DV, Requena L, Kutzner H, Fernandez-Figueras MT, Kacerovska D, Mentzel T, Schwabbauer P, Michal M: Morphologic diversity of syringocystadenocarcinoma papilliferum based on a clinicopathologic study of 6 cases and review of the literature. Am J Dermatopathol; 2010 Jun;32(4):340-7
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  • [Title] Morphologic diversity of syringocystadenocarcinoma papilliferum based on a clinicopathologic study of 6 cases and review of the literature.
  • Syringocystadenocarcinoma papilliferum is an extremely rare cutaneous adnexal neoplasm.
  • The purpose of our investigation was to study a series of syringocystadenocarcinoma papilliferum to document morphologic variations of the neoplasm.
  • Additionally, an invasive component was represented by squamous cell carcinoma.
  • The ductal changes included patterns identical to columnar cell change (flat epithelial atypia), usual ductal hyperplasia, atypical ductal hyperplasia, and ductal carcinoma in situ.
  • It is concluded that morphologic diversity of syringocystadenocarcinoma papilliferum is substantial.
  • Its association with the benign counterpart and ductal changes suggests a transformation that may involve usual ductal hyperplasia-atypical ductal hyperplasia-(ductal) adenocarcinoma in situ-invasive adenocarcinoma pathway.
  • [MeSH-minor] Adenoma, Sweat Gland / pathology. Aged. Aged, 80 and over. Carcinoma in Situ / pathology. Carcinoma, Ductal / pathology. Carcinoma, Squamous Cell / pathology. Female. Humans. Male. Middle Aged

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  • (PMID = 20216201.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 25
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63. Rufforny I, Wilkinson EJ, Liu C, Zhu H, Buteral M, Massoll NA: Human papillomavirus infection and p16(INK4a) protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma. J Low Genit Tract Dis; 2005 Apr;9(2):108-13
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  • [Title] Human papillomavirus infection and p16(INK4a) protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma.
  • METHODS: A total of 49 vulvar biopsy samples were examined by hematoxylin-eosin staining from benign/reactive lesions, condyloma acuminatum, VIN, and invasive squamous cell carcinoma (SCC).
  • RESULTS: p16(INK4a) immunoreactivity was different in VIN 1, VIN 2, VIN 3, and squamous cell carcinoma.
  • No p16(INK4a) immunoreactivity was observed in any of the benign/reactive and condyloma acuminatum lesions.
  • In addition, none of the benign/reactive or condyloma lesions were positive for HPV type 16 by RT-PCR analysis.
  • CONCLUSIONS: Upregulation of INK4a gene occurs in vulvar carcinogenesis. p16(INK4a) is not a sensitive marker for differentiation of benign vulvar squamous epithelium from condyloma acuminatum or VIN 1 lesions because most VIN 1 lesions are p16(INK4a) negative.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma in Situ / pathology. Carcinoma, Squamous Cell / pathology. Cyclin-Dependent Kinase Inhibitor p16 / analysis. Papillomavirus Infections / pathology. Vulvar Neoplasms / pathology
  • [MeSH-minor] Adult. DNA, Viral / genetics. Female. Humans. Immunohistochemistry. Middle Aged. Neoplasm Invasiveness. Papillomaviridae / genetics. Polymerase Chain Reaction. Vulva / chemistry. Vulva / pathology. Vulva / virology

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  • (PMID = 15870532.001).
  • [ISSN] 1089-2591
  • [Journal-full-title] Journal of lower genital tract disease
  • [ISO-abbreviation] J Low Genit Tract Dis
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / DNA, Viral
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64. Bechert CJ, Stern JB: Basal cell carcinoma with perineural invasion: reexcision perineural invasion? J Cutan Pathol; 2010 Mar;37(3):376-9
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  • [Title] Basal cell carcinoma with perineural invasion: reexcision perineural invasion?
  • BACKGROUND: Perineural invasion (PI) in basal cell and squamous cell carcinomas, especially of the head and neck, has been reported to indicate an increased morbidity.
  • Reexcision perineural invasion (RPI), a benign mimic of tumoral perineural invasion, may present a difficult histologic differential diagnosis.
  • METHODS: We surveyed the medical literature for PI occurring in basal cell carcinomas to investigate the degree to which the reported cases occurred in reexcision specimens vs. primary biopsy specimens.
  • RESULTS: We found large retrospective studies of 14,120 basal cell carcinomas evaluated for PI in which 310 cases of PI were identified (2.2%), and 20 sporadic case reports of basal cell carcinomas with PI.
  • Of 310 cases of basal cell carcinoma with PI, 196 (63%) were in reexcision specimens.
  • CONCLUSION: The high percentage of PI occurring in reexcision specimens vs. primary excisions may indicate that many of the reported cases of basal cell carcinomas with PI are actually examples of RPI.
  • [MeSH-major] Carcinoma, Basal Cell / pathology. Neoplasm Invasiveness / pathology. Neoplasm Seeding. Skin Neoplasms / pathology
  • [MeSH-minor] Biopsy. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Humans. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Reoperation. Retrospective Studies


65. Katori H, Nozawa A, Tsukuda M: Histopathological parameters of recurrence and malignant transformation in sinonasal inverted papilloma. Acta Otolaryngol; 2006 Feb;126(2):214-8
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  • CONCLUSIONS: A combination of parameters may be useful in predicting the clinical course of squamous cell carcinoma in inverted papilloma (IP).
  • In particular, the parameters hyperkeratosis, squamous epithelial hyperplasia and high mitotic index were negative prognostic indicators.
  • OBJECTIVE: To define histopathological parameters which could predict the recurrence and development of squamous cell carcinoma in IP.
  • MATERIAL AND METHODS: We analyzed the histopathological characteristics of 39 cases of IP using the following parameters: site of origin of tumor; presence of bone invasion; presence of inflammatory polyp; ratio of endophytic to exophytic lesions; ratio of neoplastic epithelium to stroma; presence of hyperkeratosis; presence of squamous epithelial hyperplasia; mitotic index; number of mucin globules; and number of eosinophils.
  • RESULTS: Malignancy was related to the presence of bone invasion (p=0.039), the absence of inflammatory polyp (p=0.033), increase in the ratio neoplastic epithelium:stroma (p=0.037), increase in hyperkeratosis (p=0.030), the presence of squamous epithelial hyperplasia (p=0.044), increase in the mitotic index (p=0.029) and a decrease in the number of eosinophils (p=0.037).
  • Multiple recurrences (without malignancy) were related to frontal sinus origin (p=0.042), increase in hyperkeratosis (p=0.041), the presence of squamous epithelial hyperplasia (p=0.044) and increase in the mitotic index (p=0.031).
  • Clinically benign behavior was related to the presence of inflammatory polyp (p=0.010) and the absence of hyperkeratosis (p=0.008).
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Cell Transformation, Neoplastic / pathology. Neoplasm Recurrence, Local / pathology. Papilloma, Inverted / pathology. Paranasal Sinus Neoplasms / pathology

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  • (PMID = 16428203.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
  • [Chemical-registry-number] 0 / Mucins
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66. Tabibi A, Parvin M, Abdi H, Bashtar R, Zamani N, Abadpour B: Correlation between size of renal cell carcinoma and its grade, stage, and histological subtype. Urol J; 2007;4(1):10-3
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  • [Title] Correlation between size of renal cell carcinoma and its grade, stage, and histological subtype.
  • INTRODUCTION: The aim of this study was to determine the correlation between histological subtype, size, grade, and stage of the kidney tumors and to investigate whether a correlation exists between the size of the kidney tumor and its behavior.
  • MATERIALS AND METHODS: Between 1996 and 2004, we had 212 patients with radical or partial nephrectomy due to a kidney tumor at Shaheed Labbafinejad Medical Center.
  • Their pathologic blocks were re-evaluated with consideration of their tumor size and pathologic features.
  • RESULTS: Of 212 pathologic blocks, 17 (8%) were benign and 195 (92%) were malignant masses including 179 renal cell carcinoma (RCC) tumors.
  • Malignant tumors were slightly greater compared with the benign ones (P=.10).
  • There was no significant relation between the size of tumor and the histological subtype.
  • Significant relations between the size of the kidney tumor and the nuclear grade (P=.007), clinical symptoms (P=.02), and extracapsular extension (P<.001) were observed.
  • CONCLUSION: Tumor size is not an independent predictor for the histological subtype of the tumors; however, larger malignant tumors may have higher grades, higher stages, and clinical symptoms.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Tumor Burden
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Carcinoma, Transitional Cell / pathology. Carcinoma, Transitional Cell / surgery. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Neoplasm Staging. Nephrectomy. Sarcoma / pathology. Sarcoma / surgery. Wilms Tumor / pathology. Wilms Tumor / surgery

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  • (PMID = 17514604.001).
  • [ISSN] 1735-1308
  • [Journal-full-title] Urology journal
  • [ISO-abbreviation] Urol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
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67. Szyfter W, Wierzbicka M, Jackowska J, Bartochowska A, Banaszewski J: [The schedule of intralesional papillomatosis treatment with cidofovir]. Otolaryngol Pol; 2010 Mar-Apr;64(2):98-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • It is characterized by proliferation of benign squamous cell papillomas within the respiratory-digestive tract, predominantly the larynx.
  • [MeSH-major] Antineoplastic Agents / administration & dosage. Cytosine / analogs & derivatives. Laryngeal Neoplasms / drug therapy. Neoplasm Recurrence, Local / drug therapy. Organophosphonates / administration & dosage. Papilloma / drug therapy. Respiratory Tract Neoplasms / drug therapy

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  • (PMID = 20568538.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Organophosphonates; 8J337D1HZY / Cytosine; JIL713Q00N / cidofovir
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68. Chakra M, Pujol JL, Lamy PJ, Bozonnat MC, Quantin X, Jacot W, Daurès JP: Circulating serum vascular endothelial growth factor is not a prognostic factor of non-small cell lung cancer. J Thorac Oncol; 2008 Oct;3(10):1119-26
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  • [Title] Circulating serum vascular endothelial growth factor is not a prognostic factor of non-small cell lung cancer.
  • INTRODUCTION: High circulating serum vascular endothelial growth factor (VEGF) levels might reflect enhanced angiogenesis in patients suffering from non-small cell lung cancer (NSCLC).
  • RESULTS: Receiver operating characteristic curves (area under the ROC curve: 0.66 +/- 0.05) showed that circulating VEGF serum level did not demonstrate a high sensitivity-specificity relationship, and therefore, demonstrated a low ability to differentiate NSCLC from benign lung diseases.
  • This finding does not preclude a putative prognostic impact of in situ detection of VEGF and VEGF receptors in tumor specimen.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoma, Non-Small-Cell Lung / blood. Lung Neoplasms / blood. Vascular Endothelial Growth Factor A / blood
  • [MeSH-minor] Adenocarcinoma / blood. Adenocarcinoma / secondary. Adenocarcinoma / therapy. Antigens, Neoplasm / blood. Carcinoma, Large Cell / blood. Carcinoma, Large Cell / secondary. Carcinoma, Large Cell / therapy. Carcinoma, Squamous Cell / blood. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / therapy. Combined Modality Therapy. Female. Humans. Keratin-19. Keratins / blood. Male. Middle Aged. Phosphopyruvate Hydratase / blood. Prognosis. Prospective Studies. ROC Curve. Survival Rate

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  • (PMID = 18827607.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Keratin-19; 0 / VEGFA protein, human; 0 / Vascular Endothelial Growth Factor A; 0 / antigen CYFRA21.1; 68238-35-7 / Keratins; EC 4.2.1.11 / Phosphopyruvate Hydratase
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69. Kuivanen TT, Jeskanen L, Kyllönen L, Impola U, Saarialho-Kere UK: Transformation-specific matrix metalloproteinases, MMP-7 and MMP-13, are present in epithelial cells of keratoacanthomas. Mod Pathol; 2006 Sep;19(9):1203-12
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  • Keratoacanthomas are rapidly growing hyperproliferative skin tumors that may clinically or histologically be difficult to distinguish from well-differentiated squamous cell cancers (SCCs).
  • Frequent expression of the transformation-specific MMP-13 in keratoacanthomas suggests that they are not benign tumors but incomplete SCCs.
  • [MeSH-major] Carcinoma, Squamous Cell / enzymology. Collagenases / metabolism. Keratinocytes / enzymology. Keratoacanthoma / enzymology. Matrix Metalloproteinase 7 / metabolism. Skin Neoplasms / enzymology
  • [MeSH-minor] Aged. Aged, 80 and over. Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. Cyclin-Dependent Kinase Inhibitor p16 / metabolism. Diagnosis, Differential. Female. Fibroblasts / enzymology. Fibroblasts / pathology. Humans. In Situ Hybridization. Male. Matrix Metalloproteinase 13. Middle Aged. Neoplasm Proteins / genetics. Neoplasm Proteins / metabolism. RNA, Messenger / metabolism

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  • [Copyright] Published online 12 May 2006.
  • (PMID = 16699496.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Cyclin-Dependent Kinase Inhibitor p16; 0 / Neoplasm Proteins; 0 / RNA, Messenger; EC 3.4.24.- / Collagenases; EC 3.4.24.- / MMP13 protein, human; EC 3.4.24.- / Matrix Metalloproteinase 13; EC 3.4.24.23 / MMP7 protein, human; EC 3.4.24.23 / Matrix Metalloproteinase 7
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70. Brouha XD, Tromp DM, de Leeuw JR, Hordijk GJ, Winnubst JA: Laryngeal cancer patients: analysis of patient delay at different tumor stages. Head Neck; 2005 Apr;27(4):289-95
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  • [Title] Laryngeal cancer patients: analysis of patient delay at different tumor stages.
  • Only tumor site was significantly associated with patient delay.
  • Medical attention was postponed because symptoms were interpreted as innocuous/benign or the symptom was thought not to be serious enough.
  • [MeSH-major] Carcinoma, Squamous Cell / psychology. Laryngeal Neoplasms / psychology. Patient Acceptance of Health Care / psychology
  • [MeSH-minor] Aged. Appointments and Schedules. Attitude to Health. Cohort Studies. Common Cold / psychology. Female. Glottis / pathology. Health Behavior. Hoarseness / psychology. Humans. Lymphatic Metastasis / pathology. Male. Neoplasm Staging. Voice Disorders / psychology

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  • (PMID = 15668927.001).
  • [ISSN] 1043-3074
  • [Journal-full-title] Head & neck
  • [ISO-abbreviation] Head Neck
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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71. Xu AH, Yin YW, Chen FH: [The value of serum endostatin level in early diagnosis of lung cancer]. Zhonghua Yi Xue Za Zhi; 2006 Jul 18;86(27):1916-8
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  • Twenty patients with benign lung disease and 20 normal persons were used as controls. RESULTS:.
  • (1) The serum endostatin level of the lung cancer patients was 10.71 +/- 9.99) ng/ml, significantly higher than those of the patients with benign lung diseases and the normal persons (4.79 +/- 1.23 ng/ml and 4.51 +/- 1.14 ng/ml, respectively, both P < 0.01). (2) The serum endostatin level of the lung cancer patients at the stage I and II were 13.63 +/- 13.13 ng/ml and 12.35 +/- 5.79 ng/ml respectively, booth significantly higher than that of the patients at the stage III (6.29 +/- 1.64, P = 0.023 and P = 0.023). (3) There were no significant differences in the serum endostatin level among the lung cancer patients with different pathological types. (4) The serum endostatin level of the lung cancer patients after chemotherapy was 7.83 +/- 1.48 ng/ml, significantly higher than that before the chemotherapy (5.59 +/- 1.74, P = 0.04).
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Aged. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / pathology. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Early Diagnosis. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Serologic Tests

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  • (PMID = 17064531.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Endostatins
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72. Chang X, Han J, Pang L, Zhao Y, Yang Y, Shen Z: Increased PADI4 expression in blood and tissues of patients with malignant tumors. BMC Cancer; 2009;9:40
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  • METHODS: Expression of PADI4 was investigated in various tumors and non-tumor tissues (n = 1673) as well as in A549, SKOV3 and U937 tumor cell lines by immunohistochemistry, real-time PCR, and western blot.
  • RESULTS: Immunohistochemistry detected significant PADI4 expression in various malignancies including breast carcinomas, lung adenocarcinomas, hepatocellular carcinomas, esophageal squamous cancer cells, colorectal adenocarcinomas, renal cancer cells, ovarian adenocarcinomas, endometrial carcinomas, uterine adenocarcinomas, bladder carcinomas, chondromas, as well as other metastatic carcinomas.
  • However, PADI4 expression was not observed in benign leiomyomas of stomach, uterine myomas, endometrial hyperplasias, cervical polyps, teratomas, hydatidiform moles, trophoblastic cell hyperplasias, hyroid adenomas, hemangiomas, lymph hyperplasias, schwannomas, neurofibromas, lipomas, and cavernous hemangiomas of the liver.
  • Additionally, PADI4 expression was not detected in non-tumor tissues including cholecystitis, cervicitis and synovitis of osteoarthritis, except in certain acutely inflamed tissues such as in gastritis and appendicitis.
  • Quantitative PCR and western blot analysis showed higher PADI4 expression in gastric adenocarcinomas, lung adenocarcinomas, hepatocellular carcinomas, esophageal squamous cell cancers and breast cancers (n = 5 for each disease) than in the surrounding healthy tissues.
  • Furthermore, western blot analysis detected PADI4 expression in cultured tumor cell lines.
  • ELISA detected increased PADI4 and cAT levels in the blood of patients with various malignant tumors compared to those in patients with chronic inflammation and benign tumors.
  • Additionally, PADI4 and cAT levels were significantly associated with higher levels of known tumor markers.
  • [MeSH-major] Hydrolases / metabolism. Neoplasm Proteins / metabolism. Neoplasms / metabolism
  • [MeSH-minor] Antithrombins / metabolism. Blotting, Western. Cell Line, Tumor. Citrulline / metabolism. Enzyme-Linked Immunosorbent Assay. Female. Humans. Immunohistochemistry. Immunoprecipitation. Male. Polymerase Chain Reaction / methods

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  • [Cites] Tumori. 1998 May-Jun;84(3):364-7 [9678618.001]
  • [Cites] Pathologe. 1996 Nov;17(6):425-32 [9082363.001]
  • [Cites] J Cell Mol Med. 2004 Oct-Dec;8(4):498-508 [15601578.001]
  • [Cites] Folia Histochem Cytobiol. 2004;42(4):235-40 [15704650.001]
  • [Cites] Rheumatology (Oxford). 2005 Mar;44(3):293-8 [15561738.001]
  • [Cites] Semin Cancer Biol. 2005 Aug;15(4):309-18 [15907383.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2005 Dec;14(12):2936-42 [16365013.001]
  • [Cites] Mol Carcinog. 2006 Mar;45(3):183-96 [16355400.001]
  • [Cites] Mod Pathol. 2006 Sep;19(9):1261-9 [16799479.001]
  • [Cites] Mol Endocrinol. 2007 Jul;21(7):1617-29 [17456793.001]
  • [Cites] J Steroid Biochem Mol Biol. 2007 Aug-Sep;106(1-5):76-80 [17826626.001]
  • [Cites] World J Gastroenterol. 2008 Mar 21;14(11):1682-9 [18350599.001]
  • [Cites] Histochem Cell Biol. 2008 Jun;129(6):705-33 [18461349.001]
  • [Cites] Endocr Relat Cancer. 2008 Jun;15(2):475-83 [18509000.001]
  • [Cites] J Biol Chem. 2008 Jul 18;283(29):20060-8 [18499678.001]
  • [Cites] Mol Cell Biol. 2008 Aug;28(15):4745-58 [18505818.001]
  • [Cites] Adv Exp Med Biol. 2008;630:112-32 [18637488.001]
  • [Cites] Histopathology. 2001 Jan;38(1):62-7 [11135048.001]
  • [Cites] Cell Death Differ. 2002 May;9(5):486-92 [11973607.001]
  • [Cites] Biochem Soc Trans. 2002 Apr;30(2):173-7 [12023846.001]
  • [Cites] Biochem Soc Trans. 2002 Apr;30(2):201-7 [12023851.001]
  • [Cites] Nat Genet. 2003 Aug;34(4):395-402 [12833157.001]
  • [Cites] Best Pract Res Clin Anaesthesiol. 2004 Sep;18(3):385-405 [15212335.001]
  • [Cites] Cell. 2004 Sep 3;118(5):545-53 [15339660.001]
  • [Cites] Anticancer Res. 1990 May-Jun;10(3):579-82 [2114816.001]
  • [Cites] APMIS. 1991 Nov;99(11):981-8 [1720319.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1992;421(3):209-15 [1384221.001]
  • [Cites] Int J Cancer. 1993 Jul 9;54(5):793-806 [7686887.001]
  • [Cites] Thromb Haemost. 1998 Nov;80(5):767-72 [9843169.001]
  • (PMID = 19183436.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antithrombins; 0 / Neoplasm Proteins; 29VT07BGDA / Citrulline; EC 3.- / Hydrolases; EC 3.5.3.15 / peptidylarginine deiminase type IV
  • [Other-IDs] NLM/ PMC2637889
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73. Biswas D, Crank S: Aetiopathology of maxillary swelling--a 3-year prospective study. Eur Arch Otorhinolaryngol; 2007 Nov;264(11):1295-9
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  • A wide variety of lesions and not necessarily a malignant tumour can cause maxillary swelling.
  • Maxillary swelling was found to be caused by malignant tumours in 54.2%, benign neoplasms in 22.9% and non-neoplastic lesions in 22.9%.
  • Overall squamous cell carcinoma (22.9%) was the commonest lesion, tumour of vascular origin was the commonest benign neoplasm and odontogenic cyst was the commonest among the non-neoplastic lesions.

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  • [Cites] Laryngoscope. 1978 Aug;88(8 Pt 1):1320-32 [672364.001]
  • [Cites] AJNR Am J Neuroradiol. 1995 Feb;16(2):333-8 [7726082.001]
  • [Cites] Radiology. 1977 Oct;125(1):149-58 [197566.001]
  • [Cites] Transplant Proc. 2006 Jun;38(5):1445-7 [16797328.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 1997 Jun 20;40(2-3):181-7 [9225186.001]
  • [Cites] Indian J Dent Res. 2001 Jan-Mar;12(1):41-5 [11441801.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Jun;91(6):649-53 [11402276.001]
  • [Cites] J Clin Pathol. 1996 Feb;49(2):164-7 [8655685.001]
  • [Cites] Br J Oral Maxillofac Surg. 1988 Apr;26(2):115-9 [3163490.001]
  • [Cites] Rhinology. 2004 Sep;42(3):171-4 [15521673.001]
  • [Cites] Int J Oral Maxillofac Surg. 2006 Jan;35(1):60-6 [15876525.001]
  • [Cites] Rinsho Ketsueki. 1997 Apr;38(4):336-41 [9146064.001]
  • [Cites] Chang Gung Med J. 2002 Jan;25(1):1-8 [11926581.001]
  • [Cites] Indian J Dent Res. 2004 Jul-Sep;15(3):110-3 [15915634.001]
  • [Cites] J Laryngol Otol. 1983 Jul;97(7):657-60 [6875368.001]
  • [Cites] East Afr Med J. 2005 Sep;82(9 Suppl):S135-43 [16619689.001]
  • [Cites] Acta Otolaryngol. 2006 Mar;126(3):277-81 [16618654.001]
  • [Cites] J Indian Soc Pedod Prev Dent. 2001 Dec;19(4):157-9 [12396094.001]
  • [Cites] J Otolaryngol. 1980 Aug;9(4):361-3 [7420527.001]
  • [Cites] J Oral Maxillofac Surg. 1997 Nov;55(11):1212-6 [9371109.001]
  • [Cites] SADJ. 2001 Nov;56(11):524-7 [11885430.001]
  • [Cites] Br Dent J. 1990 Feb 10;168(3):112-5 [2306394.001]
  • [Cites] Laryngorhinootologie. 2004 May;83(5):308-16 [15143448.001]
  • [Cites] J Craniomaxillofac Surg. 1989 Nov;17(8):345-9 [2592574.001]
  • [Cites] Acta Otolaryngol Suppl. 2002;(547):75-8 [12212601.001]
  • [Cites] Bildgebung. 1995 Sep;62(3):199-201 [7496117.001]
  • [Cites] Dtsch Z Mund Kiefer Gesichtschir. 1990 Mar-Apr;14(2):122-31 [2102413.001]
  • [Cites] J Oral Pathol Med. 2003 Sep;32(8):496-8 [12901733.001]
  • [Cites] J Otolaryngol. 1999 Apr;28(2):90-4 [10212875.001]
  • [Cites] J Craniomaxillofac Surg. 1989 Nov;17(8):359-62 [2687333.001]
  • [Cites] Br J Plast Surg. 1998 Dec;51(8):584-8 [10209459.001]
  • [Cites] Int J Pediatr Otorhinolaryngol. 2000 May 30;52(3):283-6 [10841959.001]
  • (PMID = 17611767.001).
  • [ISSN] 1434-4726
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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74. Shukla A, Ho Y, Liu X, Ryscavage A, Glick AB: Cripto-1 alters keratinocyte differentiation via blockade of transforming growth factor-beta1 signaling: role in skin carcinogenesis. Mol Cancer Res; 2008 Mar;6(3):509-16
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  • Here we report that in the two-stage mouse skin carcinogenesis model, Cripto-1 is highly up-regulated in tumor promoter-treated normal skin and in benign papillomas.
  • Treatment of primary mouse keratinocytes with Cripto-1 stimulated proliferation and induced expression of keratin 8 but blocked induction of the normal epidermal differentiation marker keratin 1, changes that are hallmarks of tumor progression in squamous cancer.
  • We suggest that inhibition of TGF-beta1 by Cripto-1 may play an important role in altering the differentiation state of keratinocytes and promoting outgrowth of squamous tumors in the mouse epidermis.
  • [MeSH-major] Cell Differentiation / physiology. Epidermal Growth Factor / physiology. Membrane Glycoproteins / physiology. Neoplasm Proteins / physiology. Skin Neoplasms / physiopathology. Transforming Growth Factor beta1 / antagonists & inhibitors
  • [MeSH-minor] 9,10-Dimethyl-1,2-benzanthracene. Animals. Carcinoma, Squamous Cell. DNA Replication. Gene Expression Regulation, Neoplastic. Genes, Reporter. Keratinocytes / physiology. Mice. Protein-Serine-Threonine Kinases / physiology. Receptors, Transforming Growth Factor beta / physiology. Signal Transduction

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  • (PMID = 18337457.001).
  • [ISSN] 1541-7786
  • [Journal-full-title] Molecular cancer research : MCR
  • [ISO-abbreviation] Mol. Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA122109; United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Membrane Glycoproteins; 0 / Neoplasm Proteins; 0 / Receptors, Transforming Growth Factor beta; 0 / Tdgf1 protein, mouse; 0 / Transforming Growth Factor beta1; 57-97-6 / 9,10-Dimethyl-1,2-benzanthracene; 62229-50-9 / Epidermal Growth Factor; EC 2.7.1.11 / TGF-beta type I receptor; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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75. Devoize L, Collangettes D, Le Bouëdec G, Mishellany F, Orliaguet T, Dallel R, Baudet-Pommel M: Giant mature ovarian cystic teratoma including more than 300 teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2008 Mar;105(3):e76-9
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  • Tumor size, serum tumor markers, and patient age have been proposed as risk factors for malignancy.
  • This article reports a rare case of a giant, benign MCT of the ovary in a young woman (25 years old).
  • It had a very large size (320 x 270 x 185 mm, 10 kg), a great number of teeth (> 300), and preoperative serum level of tumor markers were elevated (CA125, 875 U/mL(-1); CA19-9, 2087 U/mL(-1); CEA, 5.1 ng/mL(-1); AFP, 23.3 ng/mL(-1); SCC, 20.7 ng/mL(-1)).
  • Based on clinical and laboratory data, tumor markers and tumor size when used alone or in combination do not appear to be useful in making a differential diagnosis between MCT and squamous cell carcinoma arising from MCT.
  • [MeSH-major] Antigens, Neoplasm / analysis. Ovarian Neoplasms / pathology. Teratoma / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Carcinoembryonic Antigen / analysis. Female. Humans. Predictive Value of Tests. Proteins / analysis. Serpins / analysis. Tooth. alpha-Fetoproteins / analysis

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  • (PMID = 18280952.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / NBR1 protein, human; 0 / Proteins; 0 / Serpins; 0 / alpha-Fetoproteins; 0 / squamous cell carcinoma-related antigen
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76. Woenckhaus M, Klein-Hitpass L, Grepmeier U, Merk J, Pfeifer M, Wild P, Bettstetter M, Wuensch P, Blaszyk H, Hartmann A, Hofstaedter F, Dietmaier W: Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers. J Pathol; 2006 Oct;210(2):192-204
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  • [Title] Smoking and cancer-related gene expression in bronchial epithelium and non-small-cell lung cancers.
  • Gene expression in surgically resected and microdissected samples of non-small-cell lung cancers (18 squamous cell carcinomas and nine adenocarcinomas), matched normal bronchial epithelium, and peripheral lung tissue from both smokers (n = 22) and non-smokers (n = 5) was studied using the Affymetrix U133A array.
  • Hierarchical cluster analysis clearly distinguished between benign and malignant tissue and between squamous cell carcinomas and adenocarcinomas.
  • One gene is a tumour suppressor gene (HLF); two genes act as oncogenes (FGFR3 and LMO3); two genes are involved in matrix degradation (MMP12 and PTHLH); three genes are related to cell differentiation (SPRR1B, RTN1, and MUC7); and five genes have not been well characterized to date.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / genetics. Lung Neoplasms / genetics. Smoking / adverse effects
  • [MeSH-minor] Adenocarcinoma / etiology. Adenocarcinoma / genetics. Adenocarcinoma / pathology. Adult. Aged. Bronchi / metabolism. Carcinoma, Squamous Cell / etiology. Carcinoma, Squamous Cell / genetics. Carcinoma, Squamous Cell / pathology. Cluster Analysis. Female. Gene Expression Profiling. Gene Expression Regulation, Neoplastic. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Staging. Oligonucleotide Array Sequence Analysis / methods. Pulmonary Alveoli / metabolism. Reverse Transcriptase Polymerase Chain Reaction / methods


77. Lu YC, Fan WJ, Shen JX, Xiao P: [CT features of parotid tumors: an analysis of 133 cases]. Ai Zheng; 2007 Nov;26(11):1263-7
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  • RESULTS: Among the 157 lesions, 110 (70.1%) were benign tumors, 18 (11.5%) were borderline tumors, and 29 (18.5%) were malignant tumors; 80 (72.7%) benign lesions and 14 (77.8%) borderline lesions located in the superficial lobe, whereas 7 (24.1%) malignant lesions located in the deep lobe and 10 (34.5%) in both the superficial lobe and the deep lobe; 99 (90.0%) benign lesions had sharp margins, 8 (44.4%) borderline lesions had sharp margins and 10 (55.6%) had partly unsharp margins, 10 (34.5%) malignant lesions had partly unsharp margins and 11 (37.9%) had unsharp margins.
  • Most benign lesions were round (68/110, 61.8%) or oval (23/110, 20.9%), while malignant lesions were often irregular (14/29, 48.3%).
  • No benign tumor involved adjacent structures.
  • CONCLUSION: On CT images, a parotid tumor located in the superficial lobe, with a round or oval contour and sharp margin, is more likely to be a benign tumor; otherwise, it might be a malignant tumor.
  • [MeSH-minor] Adenoma, Pleomorphic / pathology. Adenoma, Pleomorphic / radiography. Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Acinar Cell / pathology. Carcinoma, Acinar Cell / radiography. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / radiography. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Parotid Gland / pathology. Parotid Gland / radiography. Retrospective Studies. Young Adult

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  • (PMID = 17991330.001).
  • [Journal-full-title] Ai zheng = Aizheng = Chinese journal of cancer
  • [ISO-abbreviation] Ai Zheng
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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78. Yang JG, Li CL, Gong M, Zou LF: [The diagnostic value of FDG coincidence imaging combined with serum tumor marker assays for pulmonary lesions]. Zhonghua Zhong Liu Za Zhi; 2006 Sep;28(9):683-5
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  • [Title] [The diagnostic value of FDG coincidence imaging combined with serum tumor marker assays for pulmonary lesions].
  • OBJECTIVE: To evaluate the performance of 18F-FDG three-head tomography with coincidence imaging and serum tumor marker assays in identifying lung lesions in 104 patients with abnormal findings on chest X-ray or computer tomography.
  • The serum tumor marker test was considered positive for malignancy if the serum level of at least one marker was elevated.
  • RESULTS: 66 patients were proven to have lung cancer by pathology, and 38 patients had benign lung diseases.
  • The sensitivity, specificity, accuracy of 18F-FDG coincidence imaging and serum tumor markers in assessing lung cancers were 80. 0% , 77. 2% , 77. 9% and 56. 0% , 60. 9%, 64.
  • 18F-FDG coincidence images in assessing lung lesions showed significantly higher sensitivity, specificity and accuracy than serum tumor markers.
  • Although the determination of serum marker levels is less accurate than 18F-FDG coincidence imaging, the combination of a positive 18F-FDG coincidence result and positive tumor markers may be helpful in improving the diagnosis of lung cancers.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoma, Squamous Cell / diagnosis. Fluorodeoxyglucose F18. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Antigens, Neoplasm / blood. Carcinoembryonic Antigen / blood. Carcinoma, Small Cell / blood. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / radionuclide imaging. Female. Humans. Keratin-19. Keratins / blood. Male. Middle Aged. Phosphopyruvate Hydratase / blood. Plasma Cell Granuloma, Pulmonary / blood. Plasma Cell Granuloma, Pulmonary / diagnosis. Plasma Cell Granuloma, Pulmonary / radionuclide imaging. Positron-Emission Tomography. Prospective Studies. Radiopharmaceuticals. Sensitivity and Specificity. Tuberculosis, Pulmonary / blood. Tuberculosis, Pulmonary / diagnosis. Tuberculosis, Pulmonary / radionuclide imaging

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  • (PMID = 17274375.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / Carcinoembryonic Antigen; 0 / Keratin-19; 0 / Radiopharmaceuticals; 0 / antigen CYFRA21.1; 0Z5B2CJX4D / Fluorodeoxyglucose F18; 68238-35-7 / Keratins; EC 4.2.1.11 / Phosphopyruvate Hydratase
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79. Levy-Gabriel C: [Suspicious conjunctival lesions]. J Fr Ophtalmol; 2010 Feb;33(2):125-30
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  • [Transliterated title] Taches suspectes de la conjonctive.
  • The main conjunctival tumors are represented by (i) conjunctival melanoma, ocular surface squamous neoplasia, and conjunctival lymphoma, which are malignant tumors, and (ii) conjunctival nevus, papilloma, and choristoma, which are benign.
  • Indeed, the therapeutic approach to these two malignant diseases presents a number of particularities such as the need for surgery under general anesthesia, if possible, to minimize the risk of local dissemination and further local recurrence, and detailed information on the tumor location and measurements before surgery (Figures, diagram, sizes) to precisely define the irradiation field during complementary radiotherapy.
  • [MeSH-minor] Choristoma / diagnosis. Combined Modality Therapy. Diagnosis, Differential. Humans. Lymphoma / diagnosis. Melanoma / diagnosis. Neoplasm Staging. Neoplasms, Squamous Cell / diagnosis. Nevus / diagnosis. Papilloma / diagnosis. Pigmentation. Precancerous Conditions / diagnosis

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  • [Copyright] Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20096479.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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80. Triginelli SA, Silva-Filho AL, Traiman P, Silva FM, Chaves-Dias MC, Oliveira GC, Cunha-Melo JR: Telomerase activity in the vaginal margins of radical hysterectomy in patients with carcinoma of the cervix: correlation with histology and human papillomavirus. Int J Gynecol Cancer; 2006 May-Jun;16(3):1283-8
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  • This study was undertaken to evaluate the telomerase activity both in the tumor and in the vaginal margins of radical hysterectomy in patients with squamous cell carcinoma (SCC) of the cervix.
  • Tissue samples were taken from the tumor or cervix, anterior vaginal margin (AVM), and posterior vaginal margin (PVM).
  • The telomerase activity was significantly higher in the tumor than in the benign cervix (P < 0.001).
  • [MeSH-major] Carcinoma, Squamous Cell / enzymology. Hysterectomy. Neoplasm, Residual / diagnosis. Papillomaviridae / isolation & purification. Telomerase / metabolism. Uterine Cervical Neoplasms / surgery. Vagina / enzymology. Vaginal Neoplasms / enzymology. Vaginal Neoplasms / secondary
  • [MeSH-minor] Adult. Aged. Biomarkers, Tumor / analysis. DNA Probes, HPV. Female. Humans. Middle Aged. Polymerase Chain Reaction / methods


81. Fulciniti F, Mansueto G, Vetrani A, Accurso A, Fortunato A, Palombini L: Metaplastic breast carcinoma on fine-needle cytology samples: a report of three cases. Diagn Cytopathol; 2005 Sep;33(3):205-9
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  • One of these cases showed a peculiar mixture of malignant ductal, apocrine type, and squamous epithelial cells with fascicles of spindle cells with variable degree of atypia and was diagnosed as metaplastic carcinoma of the carcino-sarcomatous type.
  • Because of the various presentation of MBC on fine-needle cytology samples and the possible influence of needle "sampling" on the cytological specimen, the spectrum of differential diagnoses to be considered may encompass a number of benign and malignant entities, like keratinous subareolar cysts, malignant fibroepithelial lesions with myxo-chondroid stroma, and true sarcomas of the breast, with cartilaginous metaplasia.
  • [MeSH-major] Breast Neoplasms / pathology. Neoplasm Metastasis / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Carcinoma, Ductal / metabolism. Carcinoma, Ductal / pathology. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Diagnosis, Differential. Female. Humans. Middle Aged. Sarcoma / metabolism. Sarcoma / pathology

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16078244.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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82. Jacot W, Lhermitte L, Dossat N, Pujol JL, Molinari N, Daurès JP, Maudelonde T, Mangé A, Solassol J: Serum proteomic profiling of lung cancer in high-risk groups and determination of clinical outcomes. J Thorac Oncol; 2008 Aug;3(8):840-50
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  • METHODS: In the present study, we developed a serum proteomic fingerprinting approach coupled with a three-step classification method to address two important clinical questions: (i) to determine whether or not proteomic profiling differs between lung cancer and benign lung diseases in a population of smokers and (ii) to assess the prognostic impact of this profiling in lung cancer.
  • Proteomic spectra were obtained from 170 pathologically confirmed lung cancer or smoking patients with benign chronic lung disease serum samples.
  • RESULTS: Among the 228 protein peaks differentially expressed in the whole population, 88 differed significantly between lung cancer patients and benign lung disease, with area under the curve diagnostic values ranging from 0.63 to 0.84.
  • Multiprotein classifiers based on differentially expressed peaks allowed the classification of lung cancer and benign disease with an area under the curve ranging from 0.991 to 0.994.
  • Finally, in the prognosis part of the study, a 4628 Da protein was found to be significantly and independently associated with prognosis in advanced stage non-small cell lung cancer patients (p = 0.0005).
  • CONCLUSIONS: The potential markers that we identified through proteomic fingerprinting could accurately classify lung cancers in a high-risk population and predict survival in a non-small cell lung cancer population.
  • [MeSH-major] Biomarkers, Tumor / blood. Carcinoma, Non-Small-Cell Lung / blood. Lung Neoplasms / blood. Proteome / analysis
  • [MeSH-minor] Adenocarcinoma / blood. Adenocarcinoma / classification. Adenocarcinoma / secondary. Aged. Aged, 80 and over. Carcinoma, Large Cell / classification. Carcinoma, Large Cell / diagnosis. Carcinoma, Large Cell / secondary. Carcinoma, Squamous Cell / classification. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / secondary. DNA Fingerprinting / methods. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Proteomics / methods. ROC Curve. Risk Factors. Small Cell Lung Carcinoma / classification. Small Cell Lung Carcinoma / diagnosis. Small Cell Lung Carcinoma / secondary. Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization. Survival Rate

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  • (PMID = 18670301.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proteome
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83. Pietarinen-Runtti P, Apajalahti S, Robinson S, Passador-Santos F, Leivo I, Mäkitie AA: Cystic neck lesions: clinical, radiological and differential diagnostic considerations. Acta Otolaryngol; 2010 Feb;130(2):300-4
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  • This study aimed to investigate the incidence of unsuspected carcinoma in routinely excised cervical cysts at a tertiary care teaching hospital and to determine the characteristics of benign BCC and cystic malignancy in preoperative imaging.
  • PATIENTS AND METHODS: A total of 196 consecutive adult patients operated on with the initial diagnosis of benign lateral cervical cyst were identified and the hospital charts and imaging studies were reviewed.
  • RESULTS: Metastatic squamous cell carcinoma was demonstrated histologically postoperatively in six (3.1%) patients and metastatic papillary thyroid carcinoma in one (0.5%) patient.
  • [MeSH-major] Branchioma / pathology. Carcinoma, Papillary / pathology. Carcinoma, Squamous Cell / secondary. Lymphatic Metastasis / pathology. Thyroid Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Diagnosis, Differential. Female. Humans. Incidence. Male. Middle Aged. Neck. Neoplasm Staging. Prevalence. Survival Rate. Young Adult

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  • (PMID = 19593684.001).
  • [ISSN] 1651-2251
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
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84. Zhang J, Zhong W, Luo W, Zhang Z: [Expression of Endothelin-1 in laryngeal carcinoma]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Dec;20(24):1124-5
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  • METHOD: Immunohistochemical (SP) method was used to detect the expression of Endothelin-1 in 30 cases of laryngeal carcinoma,20 cases of laryngeal benign lesions and 10 cases of.
  • There is a significant difference between the laryngeal carcinoma and the laryngeal benign lesions, the laryngeal carcinoma and the normal laryngeal mucous membrane, the laryngeal benign lesions and the normal laryngeal mucous membrane( P <0. 05).
  • [MeSH-major] Carcinoma, Squamous Cell / metabolism. Endothelin-1 / metabolism. Laryngeal Neoplasms / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Case-Control Studies. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 17357519.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Endothelin-1
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85. Durucu C, Baglam T, Karatas E, Mumbuc S, Kanlikama M: Surgical treatment of inverted papilloma. J Craniofac Surg; 2009 Nov;20(6):1985-8
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  • Inverted papilloma (IP) is the most common benign tumor of the nose and the paranasal sinuses and constitutes almost 0.5% to 4% of the primary nasal tumors.
  • Two patients who had an associated squamous cell carcinoma were excluded from the study.
  • Ten patients were operated on for revision surgery, and 56 eventually had a primary tumor.
  • Patients operated on for primary tumor were included in this study.
  • The origin of the tumor was most common at the maxillary sinus, the lamina papyracea, and the ethmoid sinus.
  • The type of surgery should be determined according to the tumor stage.
  • [MeSH-minor] Adult. Aged. Endoscopy / methods. Ethmoid Sinus / surgery. Female. Humans. Male. Maxilla / surgery. Middle Aged. Nasal Obstruction / surgery. Neoplasm Recurrence, Local. Retrospective Studies

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  • (PMID = 19881382.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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86. Huang TH, Wang Z, Li Q, Li FR, Qi H, Zhou HX: [Clinical significance of enrichment and detection of circulating tumor cells in NSCLC patients with immunomagnetic beads]. Zhonghua Zhong Liu Za Zhi; 2007 Sep;29(9):676-80
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  • [Title] [Clinical significance of enrichment and detection of circulating tumor cells in NSCLC patients with immunomagnetic beads].
  • OBJECTIVE: To investigate the feasibility and clinical significance of detection of circulating tumor cells (CTCs) in peripheral blood of NSCLC patients by lung cancer cell immunomagnetic enrichment and detection kit.
  • METHODS: Four groups of patients (Group A: 18 cases with stage I lung cancer; Group B: 33 cases with stage II - IV lung cancer; Group C: 20 cases with benign pulmonary diseases; Group D: 20 healthy volunteers) were enrolled for detection of CTCs using the lung cancer cell enrichment and detection kit developed by ourselves, and compared with the results obtained using simple ICC method and the detection of CK19 mRNA and LUNX mRNA using nested PCR as control.
  • RESULTS: By using lung cancer cell enrichment and detection kit, it was revealed that the detection rates of CK positive cells were 33.3%, 60.6%, 0% and 0% in Group A, B, C and D, respectively.
  • There was a significant difference between the results obtained by lung cancer cell enrichment and detection kit and simple ICC method (P < 0.05), while no significant difference was found between the results obtained by lung cancer cell enrichment and detection kit and nested RT-PCR (P > 0.05).
  • The micrometastasis in peripheral blood was closely related with pathological types, cell differentiation and TNM staging (P < 0.05).
  • CONCLUSION: The lung cancer cell enrichment and detection kit developed by ourselves is a sensitive and reliable method to detect CTCs in patients with NSCLC.
  • It may be helpful in diagnosis of NSCLC micrometastasis and circulating tumor cells in peripheral blood, re-determination of clinical stage and provide important information for cancer-therapy personalization.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / pathology. Glycoproteins / metabolism. Immunomagnetic Separation / methods. Keratin-19 / metabolism. Lung Neoplasms / pathology. Neoplastic Cells, Circulating / pathology. Phosphoproteins / metabolism
  • [MeSH-minor] Adenocarcinoma / metabolism. Adenocarcinoma / pathology. Adult. Aged. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Female. Humans. Male. Middle Aged. Neoplasm Staging. RNA, Messenger / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 18246797.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / BPIFA1 protein, human; 0 / Glycoproteins; 0 / Keratin-19; 0 / Phosphoproteins; 0 / RNA, Messenger
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87. Batinac T, Zamolo G, Coklo M, Hadzisejdic I: Possible key role of granzyme B in keratoacanthoma regression. Med Hypotheses; 2006;66(6):1129-32
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  • It is still controversial whether keratoacanthoma is to be considered as a well differentiated variant of squamous cell-carcinoma or a separate entity.
  • As opposed to malignant potential of squamous cell-carcinoma, keratoacanthoma is characterized by a spontaneous regression.
  • Within the past few years, it has become evident that the molecular events regulating cell survival and apoptosis are important contributors to the overall kinetics of benign and malignant cell growth.
  • Immunological mechanisms have been implicated in a phenomenon of spontaneous tumor regression.
  • Recent studies suggested that the tumor regression is dependent mainly on the immune response mediated by cytotoxic T lymphocytes (CD8+), together with helper T cells (CD4+).
  • Cytotoxic T lymphocytes can kill tumor cells and mediate tumor regression in vivo through two distinct molecular mechanisms: Fas/Fas ligand and granzyme B/perforin mediated pathways.
  • Tumor cells are capable of developing different escape mechanisms in order to overcome their sensitivity to apoptotic signals.
  • However, granzyme B, contained in cytolytic granules released upon target cell recognition, can also cause tumor cell death and consequently tumor regression by direct damage to non-nuclear structures through a caspase-independent pathway.
  • Therefore, we propose a key role of plasticity in the granzyme B mediated cell death pathway in the killing of changed tumor cells, resulting in keratoacanthoma regression through apoptosis or direct damage of tumor cells.
  • On the other hand, insufficient activation of cytotoxic T lymphocytes and decreased release or activity of granzyme B could be responsible for squamous cell-carcinoma progression and occasional aggressive behavior in keratoacanthomas.
  • As a first step in confirming or refuting our hypothesis, we suggest a thorough immunohistochemical study of the presence of granzyme B and its activity in keratoacanthoma and squamous cell-carcinoma samples.
  • [MeSH-major] Carcinoma, Squamous Cell / immunology. Keratoacanthoma / immunology. Models, Immunological. Neoplasm Regression, Spontaneous / immunology. Serine Endopeptidases / immunology. Signal Transduction / immunology. T-Lymphocytes / immunology

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  • (PMID = 16497444.001).
  • [ISSN] 0306-9877
  • [Journal-full-title] Medical hypotheses
  • [ISO-abbreviation] Med. Hypotheses
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
  • [Chemical-registry-number] EC 3.4.21.- / GZMB protein, human; EC 3.4.21.- / Granzymes; EC 3.4.21.- / Serine Endopeptidases
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88. Hafidh MA, Lacy PD, Hughes JP, Duffy G, Timon CV: Evaluation of the impact of addition of PET to CT and MR scanning in the staging of patients with head and neck carcinomas. Eur Arch Otorhinolaryngol; 2006 Sep;263(9):853-9
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  • The addition of whole body positron emission tomography (PET) to the investigation of patients with newly diagnosed head and neck squamous cell carcinoma (HNSCC) was assessed over a 6-month period.
  • SUV levels above 5 were considered indicative of the presence of tumour, values below 3 indicative of benign aetiology and values equal to and between 3 and 5 were considered equivocal.
  • None of the three imaging modalities was able to identify the tumour site in the three patients with unknown primaries.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Head and Neck Neoplasms / pathology. Magnetic Resonance Imaging / methods. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prospective Studies. ROC Curve. Sensitivity and Specificity

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  • [Cites] Arch Otolaryngol Head Neck Surg. 2003 Nov;129(11):1173-8 [14623746.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2002 Jun;128(6):703-7 [12049568.001]
  • [Cites] Head Neck. 2000 Mar;22(2):105-10 [10679897.001]
  • [Cites] AJR Am J Roentgenol. 1997 Dec;169(6):1663-9 [9393187.001]
  • [Cites] Radiology. 2004 Apr;231(1):65-72 [14990824.001]
  • [Cites] Head Neck. 2002 Apr;24(4):345-9 [11933176.001]
  • [Cites] BMJ. 1994 Jul 16;309(6948):188 [8044101.001]
  • [Cites] J Laryngol Otol. 2002 Mar;116(3):194-9 [11893261.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2004 Aug 1;59(5):1295-300 [15275712.001]
  • [Cites] J Nucl Med. 1995 Oct;36(10 ):1747-57 [7562038.001]
  • [Cites] J Nucl Med. 1995 Feb;36(2):211-6 [7830116.001]
  • [Cites] Radiology. 1999 Jan;210(1):177-81 [9885604.001]
  • [Cites] Laryngoscope. 1995 Feb;105(2):135-9 [8544591.001]
  • [Cites] Head Neck. 1998 Dec;20(8):739-44 [9790297.001]
  • [Cites] Laryngoscope. 1992 Mar;102(3):281-8 [1545657.001]
  • [Cites] Otolaryngol Head Neck Surg. 2000 Sep;123(3):294-301 [10964310.001]
  • [Cites] Radiology. 1993 Jan;186(1):27-35 [8416578.001]
  • [Cites] Laryngoscope. 1995 Apr;105(4 Pt 1):373-5 [7715380.001]
  • [Cites] Oral Oncol. 1999 Jul;35(4):390-4 [10645404.001]
  • [Cites] Nuklearmedizin. 2004 Jun;43(3):91-101;quiz 102-4 [15201950.001]
  • [Cites] J Otolaryngol. 2005 Dec;34(6):384-94 [16343398.001]
  • [Cites] Head Neck. 1996 Nov-Dec;18(6):545-51 [8902568.001]
  • [Cites] Head Neck. 2005 Jun;27(6):494-502 [15772951.001]
  • [Cites] Eur Arch Otorhinolaryngol. 1993;250(1):11-7 [8466744.001]
  • [Cites] Clin Otolaryngol Allied Sci. 1994 Feb;19(1):63-9 [8174305.001]
  • [Cites] Radiology. 2005 May;235(2):580-6 [15858097.001]
  • [Cites] J Nucl Med. 2004 Aug;45(8):1328-33 [15299057.001]
  • [Cites] Head Neck. 2003 Feb;25(2):138-45 [12509797.001]
  • (PMID = 16724209.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] Germany
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89. Han Z, Lin GJ, Chi FL, Wang SY, Huang JM, Liu HJ, Zhang LR: The relationship between the extracellular matrix and the angiogenesis and metastasis of laryngeal carcinoma. ORL J Otorhinolaryngol Relat Spec; 2008;70(6):352-8
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  • METHODS: Thirty-three cases of benign and malignant laryngeal tumors were included.
  • RESULTS: The expression of ECM1 (p = 0.004) and HA (p = 0.036) was significantly different between benign and malignant tumors.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Squamous Cell / secondary. Extracellular Matrix Proteins / metabolism. Laryngeal Neoplasms / pathology. Neovascularization, Pathologic / pathology
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Cohort Studies. Female. Humans. Immunohistochemistry. Lymph Nodes / pathology. Male. Middle Aged. Neoplasm Invasiveness / pathology. Neoplasm Metastasis. Neoplasm Staging. Probability. Prognosis. Risk Assessment. Sampling Studies. Sensitivity and Specificity. Statistics, Nonparametric. Survival Analysis

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • [Copyright] Copyright 2008 S. Karger AG, Basel.
  • (PMID = 18984970.001).
  • [ISSN] 1423-0275
  • [Journal-full-title] ORL; journal for oto-rhino-laryngology and its related specialties
  • [ISO-abbreviation] ORL J. Otorhinolaryngol. Relat. Spec.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / ECM1 protein, human; 0 / Extracellular Matrix Proteins
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90. Tan Y, Meng HP, Wu Q, Wang FQ, Wu HR: [Proteomic study of gallbladder cancer, with special reference on the expression and significance of annexin A3]. Zhonghua Bing Li Xue Za Zhi; 2010 Jun;39(6):382-6
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  • OBJECTIVE: To explore the potential molecular targets for diagnosis and treatment of gallbladder cancer by analyzing and comparing the proteomes expressed in human gallbladder cancer and benign gallbladder tissues.
  • CONCLUSIONS: Significant discrepancies in protein expression exist among gallbladder cancer and benign gallbladder tissues.
  • [MeSH-minor] Adult. Aged. Carcinoma, Adenosquamous / metabolism. Carcinoma, Adenosquamous / pathology. Carcinoma, Adenosquamous / surgery. Carcinoma, Squamous Cell / metabolism. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / surgery. Cholecystitis / metabolism. Electrophoresis, Gel, Two-Dimensional. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Metastasis. Proteome / metabolism. Proteomics. Survival Rate

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  • (PMID = 21055154.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Proteome; EC 3.1.4.43 / Annexin A3
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91. Ababneh KT: Biopsied gingival lesions in northern Jordanians: A retrospective analysis over 10 years. Int J Periodontics Restorative Dent; 2006 Aug;26(4):387-93
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  • Neoplasms accounted for 9% of biopsies (7% benign, 3% malignant).
  • The most frequent neoplasm was peripheral ossifying fibroma.
  • The maximum number of benign neoplasms occurred in patients aged 20 to 39 years, and malignant neoplasms did not occur in patients younger than 30 years.
  • [MeSH-minor] Adolescent. Adult. Age Factors. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / epidemiology. Child. Female. Fibroma, Ossifying / epidemiology. Gingival Hyperplasia / epidemiology. Gingival Neoplasms / epidemiology. Granuloma, Giant Cell / epidemiology. Granuloma, Pyogenic / epidemiology. Humans. Jordan / epidemiology. Male. Middle Aged. Retrospective Studies. Sex Factors

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  • (PMID = 16939021.001).
  • [ISSN] 0198-7569
  • [Journal-full-title] The International journal of periodontics & restorative dentistry
  • [ISO-abbreviation] Int J Periodontics Restorative Dent
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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92. Cilli A, Ozkaynak C, Onur R, Erogullari I, Ogus C, Cubuk M, Arslan G, Ozdemir T: Lung cancer detection with low-dose spiral computed tomography in chronic obstructive pulmonary disease patients. Acta Radiol; 2007 May;48(4):405-11
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  • Of the 374 COPD subjects, nine patients with primary lung cancer (2.4%) were detected: six were squamous cell carcinomas, two were small-cell lung carcinomas (SCLC), and one was adenosquamous carcinoma.
  • One subject with stage IA squamous cell carcinoma received radiotherapy, as pulmonary function was severely impaired.
  • In addition, four patients underwent removal of benign lesions.
  • [MeSH-minor] Adult. Aged. Biopsy, Needle. Bronchoscopy. Calcinosis / radiography. Carcinoma, Adenosquamous / radiography. Carcinoma, Small Cell / radiography. Carcinoma, Squamous Cell / radiography. Female. Follow-Up Studies. Humans. Male. Mass Screening. Middle Aged. Neoplasm Staging. Pneumonectomy. Radiation Dosage. Solitary Pulmonary Nodule / radiography. Sputum / cytology. Thoracic Surgery, Video-Assisted


93. Driemel O, Dahse R, Berndt A, Pistner H, Hakim SG, Zardi L, Reichert TE, Kosmehl H: High-molecular tenascin-C as an indicator of atypical cells in oral brush biopsies. Clin Oral Investig; 2007 Mar;11(1):93-9
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  • Tumour-invasion like wound healing is characterised by the formation of an extracellular matrix with a high tenascin-C content.
  • Analysis using antibody BC2 indicates that especially the high-molecular tenascin-C (hm tn-C) variants are typically tumour-associated, while distribution in normal tissue is restrictive.
  • Conventional cytology produced four false-positives when identifying atypical cells in brush biopsies of inflammatory/benign hyperproliferative mucosa (specificity 96%), while 10 in 52 carcinomas and three of eight recurrences were not identified (sensitivity 78%).
  • [MeSH-major] Biomarkers, Tumor / analysis. Biopsy / methods. Carcinoma, Squamous Cell / pathology. Mouth Neoplasms / pathology. Tenascin / analysis
  • [MeSH-minor] Epithelial Cells / pathology. Humans. Immunoenzyme Techniques. Mouth Mucosa / pathology. Neoplasm Invasiveness / pathology. Prospective Studies. Sensitivity and Specificity

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  • [Cites] Anal Cell Pathol. 2003;25(3):139-46 [12775918.001]
  • [Cites] Int J Biochem Cell Biol. 2004 Jun;36(6):986-90 [15094113.001]
  • [Cites] Br J Cancer. 2006 Apr 24;94(8):1170-5 [16622441.001]
  • [Cites] Int J Mol Med. 2000 May;5(5):505-10 [10762653.001]
  • [Cites] Cancer. 2001 Sep 15;92(6):1419-26 [11745218.001]
  • [Cites] J Am Dent Assoc. 1999 Oct;130(10):1445-57 [10570588.001]
  • [Cites] J Oral Pathol Med. 2006 Sep;35(8):520; author reply 520-2 [16918607.001]
  • [Cites] Int J Cancer. 2002 Aug 20;100(6):719-22 [12209613.001]
  • [Cites] Int J Cancer. 1997 Jul 17;72(2):236-40 [9219826.001]
  • [Cites] Int J Cancer. 1992 Nov 11;52(5):688-92 [1385335.001]
  • [Cites] Oncology. 2003;64(3):245-50 [12697965.001]
  • [Cites] Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003 Sep;96(3):252 [14515857.001]
  • [Cites] Anal Cell Pathol. 2001;22(4):211-21 [11564897.001]
  • [Cites] Biochem Cell Biol. 1997;75(6):759-69 [9599665.001]
  • [Cites] J Pathol. 2003 Jul;200(4):429-47 [12845611.001]
  • [Cites] J Pathol. 2004 Jul;203(3):771-9 [15221936.001]
  • [Cites] Int J Cancer. 1998 Mar 2;75(5):680-7 [9495234.001]
  • [Cites] Oral Oncol. 2004 Sep;40(8):824-8 [15288838.001]
  • [Cites] J Oral Pathol Med. 2006 Jan;35(1):58-60 [16393256.001]
  • [Cites] Cancer Res. 2002 Jun 1;62(11):3289-97 [12036947.001]
  • [Cites] Cytopathology. 2007 Dec;18(6):348-55 [18031447.001]
  • [Cites] J Oral Pathol Med. 1994 Nov;23(10):446-50 [7532219.001]
  • [Cites] J Oral Pathol Med. 2004 Aug;33(7):398-404 [15250831.001]
  • [Cites] Histochem Cell Biol. 2006 Jul;126(1):125-31 [16344911.001]
  • [Cites] Oral Oncol. 2004 Sep;40(8):829-34 [15288839.001]
  • [Cites] J Cancer Res Clin Oncol. 2001 May;127(5):286-92 [11355143.001]
  • [Cites] Oral Oncol. 2002 Jun;38(4):332-6 [12076695.001]
  • [Cites] J Pathol. 1999 Dec;189(4):475-80 [10629546.001]
  • [Cites] Gen Dent. 2002 Nov-Dec;50(6):500-3 [12572180.001]
  • [Cites] Mund Kiefer Gesichtschir. 2004 Jul;8(4):229-36 [15293118.001]
  • (PMID = 17111122.001).
  • [ISSN] 1432-6981
  • [Journal-full-title] Clinical oral investigations
  • [ISO-abbreviation] Clin Oral Investig
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Tenascin
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94. Bloomfeld RS, Bridgers DI 3rd, Pineau BC: Sensitivity of upper endoscopy in diagnosing esophageal cancer. Dysphagia; 2005;20(4):278-82
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  • All patients with a new diagnosis of esophageal cancer from 1997 to 2001 in the Tumor Registry of Wake Forest University Baptist Medical Center were identified.
  • The reasons for the failure of endoscopy were (1) lesion not seen in seven patients, (2) lesion seen and biopsied with benign histology in two patients, and (3) lesion seen but felt to be benign and not biopsied in one patient.
  • [MeSH-major] Adenocarcinoma / diagnosis. Carcinoma, Squamous Cell / diagnosis. Esophageal Neoplasms / diagnosis. Esophagoscopy / methods
  • [MeSH-minor] Adult. Age Distribution. Aged. Aged, 80 and over. Diagnosis, Differential. Early Diagnosis. Female. Humans. Incidence. Male. Middle Aged. Neoplasm Staging. Registries. Retrospective Studies. Risk Assessment. Sensitivity and Specificity. Sex Distribution

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  • [Cites] Gastroenterology. 1997 Jan;112(1):17-23 [8978337.001]
  • [Cites] Endoscopy. 2001 Apr;33(4):348-52 [11315898.001]
  • [Cites] Gut. 2002 Mar;50(3):368-72 [11839716.001]
  • [Cites] CA Cancer J Clin. 2003 Jan-Feb;53(1):5-26 [12568441.001]
  • [Cites] Endoscopy. 1998 Oct;30(8):669-74 [9865554.001]
  • [Cites] J Natl Cancer Inst. 1981 Oct;67(4):777-83 [6944547.001]
  • [Cites] Scand J Gastroenterol. 2002 Dec;37(12):1359-65 [12523583.001]
  • [Cites] Gastroenterology. 1982 Feb;82(2):228-31 [7054024.001]
  • [Cites] Endoscopy. 2002 Feb;34(2):129-38 [11822008.001]
  • [Cites] Am J Gastroenterol. 2002 Jun;97(6):1319-27 [12094844.001]
  • (PMID = 16633872.001).
  • [ISSN] 0179-051X
  • [Journal-full-title] Dysphagia
  • [ISO-abbreviation] Dysphagia
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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95. Arens C, Glanz H, Wönckhaus J, Hersemeyer K, Kraft M: Histologic assessment of epithelial thickness in early laryngeal cancer or precursor lesions and its impact on endoscopic imaging. Eur Arch Otorhinolaryngol; 2007 Jun;264(6):645-9
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  • Retrospective study including 161 patients undergoing surgery for a total of 206 benign and malignant lesions of the vocal folds.
  • The vocal fold mucosa revealed a progressive thickening from normal epithelium (NE = 147 microm) over the different grades of epithelial dysplasia (EDI = 258 microm, EDII = 301 microm, CIS = 445 microm) to early invasive carcinoma (EIC = 974 microm), while benign lesions presented only a slight epithelial thickening of an additional 100 microm.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Laryngeal Neoplasms / pathology. Laryngoscopy / methods. Precancerous Conditions / pathology. Vocal Cords / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Fluorescence. Humans. Male. Microscopy, Fluorescence. Middle Aged. Neoplasm Invasiveness. Retrospective Studies

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  • [Cites] Acta Otolaryngol. 1986 Mar-Apr;101(3-4):331-40 [3705957.001]
  • [Cites] Lasers Surg Med. 1999;25(4):323-34 [10534749.001]
  • [Cites] Acta Otolaryngol Suppl. 1997;527:57-61 [9197483.001]
  • [Cites] Laryngoscope. 2006 Jul;116(7):1107-13 [16826043.001]
  • [Cites] Eur Arch Otorhinolaryngol. 2004 Feb;261(2):71-6 [12883822.001]
  • [Cites] Z Laryngol Rhinol Otol. 1966 Jan;45(1):1-5 [5976289.001]
  • [Cites] Acta Otolaryngol. 1997 Mar;117(2):316-9 [9105474.001]
  • [Cites] Eur Arch Otorhinolaryngol. 1999;256(6):316-22 [10456283.001]
  • [Cites] Ann Otol Rhinol Laryngol. 1995 May;104(5):333-9 [7747902.001]
  • [Cites] J Clin Pathol. 1985 May;38(5):489-95 [3889066.001]
  • [Cites] Laryngoscope. 2002 Mar;112(3):488-93 [12148859.001]
  • [Cites] J Pathol. 1995 Dec;177(4):385-93 [8568593.001]
  • (PMID = 17294207.001).
  • [ISSN] 0937-4477
  • [Journal-full-title] European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
  • [ISO-abbreviation] Eur Arch Otorhinolaryngol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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96. Kozlowski M, Kowalczuk O, Milewski R, Chyczewski L, Niklinski J, Laudański J: Serum vascular endothelial growth factors C and D in patients with oesophageal cancer. Eur J Cardiothorac Surg; 2010 Sep;38(3):260-7
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  • METHODS: Serum VEGF-C and sVEGF-D were measured by enzyme-linked immunoadsorbent assay (ELISA) on 149 patients with oesophageal cancer, 29 patients with benign oesophageal diseases and 30 healthy controls.
  • RESULTS: Serum VEGF-C and sVEGF-D levels were significantly higher in patients with oesophageal carcinoma than in the control group (p<0.001 and p=0.001, respectively) or in the benign oesophageal diseases group (p=0.04 and p=0.03, respectively).
  • Subgroup analysis showed that lymph node metastasis (p=0.001), stage (p=0.001), tumour depth (p=0.006), resectability (p=0.002), tumour size (p=0.01), distant metastases (p=0.01) and histological grading (p=0.04) were correlated with an elevated level of sVEGF-C.
  • Elevated levels of sVEGF-D were associated with tumour depth (p=0.002), stage (p=0.01) and lymph node metastasis (p=0.02).
  • On univariate regression analysis, tumour size, tumour depth, stage, lymph node metastases, distant metastases, resectability and sVEGF-C were found to be significant prognostic factors.
  • [MeSH-major] Biomarkers, Tumor / blood. Esophageal Neoplasms / diagnosis. Vascular Endothelial Growth Factor C / blood. Vascular Endothelial Growth Factor D / blood
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Diagnosis, Differential. Epidemiologic Methods. Esophageal Diseases / diagnosis. Female. Humans. Lymphatic Metastasis. Male. Middle Aged. Neoplasm Proteins / metabolism. Neoplasm Staging. Prognosis. Treatment Outcome

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  • [Copyright] Copyright 2010. Published by Elsevier B.V.
  • (PMID = 20226684.001).
  • [ISSN] 1873-734X
  • [Journal-full-title] European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • [ISO-abbreviation] Eur J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Vascular Endothelial Growth Factor C; 0 / Vascular Endothelial Growth Factor D
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97. Abdollahi A, Ayati M: Frequency and outcome of metaplasia in needle biopsies of prostate and its relation with clinical findings. Urol J; 2009;6(2):109-13
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  • INTRODUCTION: Metaplasia is a reversible change in which one adult cell type is replaced by another adult cell type.
  • RESULTS: Ten prostate specimens (0.6%) had metaplasia, of which 6 were transitional and 4 were squamous metaplasia.
  • Clinical findings on DRE and TRUS resemble those found in benign lesions of the prostate, such as BPH.
  • However, in the differential diagnosis of this benign lesion, malignant lesions, such as squamous cell carcinoma or urothelial transitional cell carcinoma, should also be taken into consideration.
  • [MeSH-minor] Age Factors. Aged. Biopsy, Needle. Cross-Sectional Studies. Diagnosis, Differential. Digital Rectal Examination / methods. Endosonography. Follow-Up Studies. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Staging. Risk Assessment. Survival Analysis. Treatment Outcome


98. Kazakov DV, Zelger B, Rütten A, Vazmitel M, Spagnolo DV, Kacerovska D, Vanecek T, Grossmann P, Sima R, Grayson W, Calonje E, Koren J, Mukensnabl P, Danis D, Michal M: Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome. Am J Surg Pathol; 2009 May;33(5):705-19
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  • [Title] Morphologic diversity of malignant neoplasms arising in preexisting spiradenoma, cylindroma, and spiradenocylindroma based on the study of 24 cases, sporadic or occurring in the setting of Brooke-Spiegler syndrome.
  • The authors present a series of 24 malignant neoplasms arising in preexisting benign spiradenoma (20), cylindroma (2), and spiradenocylindroma (2).
  • Nineteen patients (12 females, 7 males; age range, 41 to 92 y) had a solitary neoplasm (size range, 2.2 to 17.5 cm; median 4 cm), whereas the remaining 5 (4 females, 1 male; age range, 66 to 72 y) manifested clinical features of Brooke-Spiegler syndrome (BSS), an autosomal dominantly inherited disease characterized by widespread, small, benign neoplasms on which background larger malignant lesions appeared.
  • Microscopically, all cases showed the residuum of a preexisting benign neoplasm.
  • 1) salivary gland type basal cell adenocarcinoma-like pattern, low-grade (BCAC-LG);.
  • 2) salivary gland type basal cell adenocarcinoma-like pattern, high-grade (BCAC-HG);.
  • Cases harboring a sarcomatoid carcinoma featured a malignant epithelial component composed of varying combinations of BCAC-HG, BCAC-LG, IAC-NOS, or squamous cell carcinoma, whereas the sarcomatoid component appeared as either a pleomorphic or spindle-cell sarcoma.
  • The histologic pattern of the malignant neoplasm correlated to some extent with the clinical course.
  • Given the morphologic diversity and complexity of the neoplasms in question, we propose using a more specific terminology with the precise description of the neoplasm components, rather than generic and less informative terms such as "spiradenocarcinoma" or "carcinoma ex cylindroma. "
  • [MeSH-minor] Adenocarcinoma / pathology. Adult. Aged. Aged, 80 and over. Australia. Carcinoma, Skin Appendage / pathology. Carcinoma, Squamous Cell / pathology. Cell Differentiation. Chromosomes, Human, Pair 16. Europe. Female. Gene Expression Regulation, Neoplastic. Humans. Immunohistochemistry. Male. Metaplasia. Middle Aged. Mutation. Neoplasm Invasiveness. South Africa. Syndrome. Treatment Outcome. Tumor Suppressor Proteins / genetics


99. Gerdes MJ, Myakishev M, Frost NA, Rishi V, Moitra J, Acharya A, Levy MR, Park SW, Glick A, Yuspa SH, Vinson C: Activator protein-1 activity regulates epithelial tumor cell identity. Cancer Res; 2006 Aug 1;66(15):7578-88
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  • [Title] Activator protein-1 activity regulates epithelial tumor cell identity.
  • When A-FOS was expressed during chemical-induced skin carcinogenesis, mice do not develop characteristic benign and malignant squamous lesions but instead develop benign sebaceous adenomas containing a signature mutation in the H-ras proto-oncogene.
  • Inhibiting AP-1 activity after tumor formation caused squamous tumors to transdifferentiate into sebaceous tumors.
  • Furthermore, reactivating AP-1 in sebaceous tumors results in a reciprocal transdifferentiation into squamous tumors.
  • In both cases of transdifferentiation, individual cells express molecular markers for both cell types, indicating individual tumor cells have the capacity to express multiple lineages.
  • Molecular characterization of cultured keratinocytes and tumor material indicates that AP-1 regulates the balance between the wnt/beta-catenin and hedgehog signaling pathways that determine squamous and sebaceous lineages, respectively.
  • Thus, AP-1 activity regulates tumor cell lineage and is essential to maintain the squamous tumor cell identity.
  • [MeSH-major] Adenocarcinoma, Sebaceous / metabolism. Carcinoma, Squamous Cell / metabolism. Skin Neoplasms / metabolism. Transcription Factor AP-1 / metabolism
  • [MeSH-minor] Animals. DNA, Neoplasm / metabolism. Hyperplasia. Keratinocytes / metabolism. Mice. Mice, Transgenic. Precancerous Conditions / genetics. Precancerous Conditions / metabolism. Precancerous Conditions / pathology. Promoter Regions, Genetic. Protein Binding. Proto-Oncogene Proteins c-fos / biosynthesis. Proto-Oncogene Proteins c-fos / genetics. Proto-Oncogene Proteins c-jun / metabolism. Sebaceous Glands / pathology. Transcriptional Activation. Wnt Proteins / genetics


100. Niedzielska I, Sypniewski D, Mazurek U, Wilczok T, Niedzielski Z, Wziatek-Kuczmik D: Differential diagnosis of gingival hyperplasia based on IFN-gamma-stimulated gene expression using RT-PCR. Folia Biol (Praha); 2007;53(1):23-6
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  • Epulus is a benign gingival tumour of unknown aetiopathogenesis.
  • The literature does not present any molecular analysis of the tumour characteristics.
  • The purpose of the present study was to compare benign (epulus) and malignant (cancer) gingival hyperplasias with regard to the activity of the genes of apoptosis, proliferation, and inflammation using RT-PCR.
  • The investigation involved 70 patients with epuli and 15 patients with gingival squamous cell carcinoma.
  • Each subject had specimens collected from the tumour, tissue margin (incision line), and healthy tissue.
  • Correlations have been disclosed between apoptosis and proliferation genes expression in giant cell epuli and high-differentiated gingival squamous cell carcinoma.
  • In RT-PCR molecular analysis, giant cell epulus shows characteristics of a neoplastic lesion, while other epulus types seem to be inflammatory tumours.
  • [MeSH-minor] Diagnosis, Differential. Gene Expression Profiling. Humans. Neoplasm Proteins / genetics. Neoplasm Proteins / metabolism. Reverse Transcriptase Polymerase Chain Reaction

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  • (PMID = 17328839.001).
  • [ISSN] 0015-5500
  • [Journal-full-title] Folia biologica
  • [ISO-abbreviation] Folia Biol. (Praha)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Czech Republic
  • [Chemical-registry-number] 0 / Neoplasm Proteins; 82115-62-6 / Interferon-gamma
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