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3. Sato M, Takasaka I, Okumura T, Shioyama Y, Asato Y, Yoshimi F, Imura J, Amemiya R: F-18 fluorodeoxyglucose accumulation in an inflammatory pseudotumor of the spleen. Ann Nucl Med; 2007 Nov;21(9):521-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] F-18 fluorodeoxyglucose accumulation in an inflammatory pseudotumor of the spleen.
  • We report on a case with an inflammatory pseudotumor of the spleen, which showed a moderate accumulation of F-18 fluorodeoxyglucose (FDG) in the tumor.
  • F-18 FDG accumulated mainly in the peripheral portion of this tumor that showed abundant hypercellular inflammatory cells histopathologically.
  • Splenic inflammatory pseudotumors should be recognized as F-18 FDG-avid benign tumors of the spleen.
  • [MeSH-major] Fluorodeoxyglucose F18 / pharmacokinetics. Granuloma, Plasma Cell / diagnosis. Granuloma, Plasma Cell / radionuclide imaging. Spleen / radionuclide imaging

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  • (PMID = 18030584.001).
  • [ISSN] 0914-7187
  • [Journal-full-title] Annals of nuclear medicine
  • [ISO-abbreviation] Ann Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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4. Chen HW, Lai EC, Huang XJ, Chen FN, Lu RL, Pan AZ, Lau WY: Inflammatory myofibroblastic tumours of the spleen and liver. Asian J Surg; 2008 Jan;31(1):25-8
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  • [Title] Inflammatory myofibroblastic tumours of the spleen and liver.
  • Inflammatory myofibroblastic tumour (IMT) is a rare neoplasm.
  • Generally, these lesions have a benign behaviour, but the possibility of malignant transformation exists.
  • We report the rare case of a 43-year-old woman with metachronous IMTs in the spleen and the liver.
  • This case emphasizes the difficulties in diagnosis and the possibility of a metachronous occurrence.

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  • (PMID = 18334466.001).
  • [ISSN] 1015-9584
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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5. Colović R, Suvajdzić N, Grubor N, Colović N, Terzić T: Atypical immunophenotype in a littoral cell angioma. Vojnosanit Pregl; 2009 Jan;66(1):63-5
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  • BACKGROUND: Littoral-cell angioma (LCA) is a recently described benign vascular tumor of the spleen, whose imaging and pathologic characteristics have been discussed only by a few authors.
  • The tumor is characterized by a mixture of papillary and cystic areas lined by neoplastic cells deriving from normal splenic lining--littoral cells.
  • The neoplastic LCA cells express both endothelial and histiocytic antigens associated with CD8 negativity, compared with the normal endothelium of the venous sinuses of the spleen red pulp that only expresses endothelial antigens and CD8 positivity.
  • CASE REPORT: We reported a 60-year-old male with moderate nodular splenomegaly with one large hypoechogenic solid lesion and mild thrombocytopenia in whom the diagnosis of LCA was made after the elective splenectomy.
  • Namely, histopathological and immunohistochemical data allowed a final diagnosis of classical LCA in spite of CD21 negativity.
  • CONCLUSION: Littoral-cell angioma is a very rare benign splenic neoplasm that should be considered in the differential diagnosis of multinodular splenomegaly, particularly if the patient has the signs of hypersplenism.
  • [MeSH-major] Hemangioma / pathology. Splenic Neoplasms / pathology

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  • (PMID = 19195267.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Serbia
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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6. Colović N, Cemerikić-Martinović V, Micev M, Radak V, Colović R: [Hemangioma of the spleen]. Srp Arh Celok Lek; 2006 Jul-Aug;134(7-8):325-7
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  • [Title] [Hemangioma of the spleen].
  • Although the most frequent benign tumors of the spleen, hemangiomas are very rare, much rarer than hemangiomas of the liver.
  • As the investigation showed a number of hypoechogenic lesions within the enlarged, diffusely non-homogenic spleen, splenectomy was indicated.
  • The spleen weighing 2600 grams was removed, in which the number of lesions histologically corresponded to hemangioma of the spleen.
  • [MeSH-minor] Aged. Female. Humans. Splenic Neoplasms / diagnosis. Splenic Neoplasms / pathology. Splenic Neoplasms / surgery

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  • (PMID = 17009613.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia and Montenegro
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7. Ait-Ali A, Sall I, El-Kaoui H, Bouchentouf SM, El-Hjouji A, Rouibaa F, Benkirane A, Bounaim A, Zentar A, Sair K: Medial pancreatectomy for a neuroendocrine tumor invading the splenic artery and vein. JOP; 2010;11(1):75-7
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  • [Title] Medial pancreatectomy for a neuroendocrine tumor invading the splenic artery and vein.
  • CONTEXT: Pancreatic tumors in the midportion have traditionally been treated by an extended right or left pancreatectomy.
  • A medial or central pancreatectomy is an alternative technique for benign or low-grade malignant neoplasms located to the left of the gastroduodenal artery and close to the splenomesenteric confluence.
  • This tumor invaded the splenic artery and vein.
  • The patient continues to be well after a 10-month follow-up without pancreatic insufficiency or local recurrence, and CT has demonstrated splenic perfusion by the collateral vessels.
  • CONCLUSION: We believe that a medial or central pancreatectomy may be a safe procedure where there is involvement of the large splenic vessels by a low grade malignant pancreatic tumor and that a systematic splenectomy is not justified.
  • [MeSH-major] Neuroendocrine Tumors / surgery. Pancreatectomy / methods. Pancreatic Neoplasms / surgery. Splenic Artery / surgery. Splenic Vein / surgery
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Invasiveness. Splenic Neoplasms / prevention & control. Splenic Neoplasms / secondary

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  • (PMID = 20065560.001).
  • [ISSN] 1590-8577
  • [Journal-full-title] JOP : Journal of the pancreas
  • [ISO-abbreviation] JOP
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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8. O'Malley DP, Kim YS, Perkins SL, Baldridge L, Juliar BE, Orazi A: Morphologic and immunohistochemical evaluation of splenic hematopoietic proliferations in neoplastic and benign disorders. Mod Pathol; 2005 Dec;18(12):1550-61
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  • [Title] Morphologic and immunohistochemical evaluation of splenic hematopoietic proliferations in neoplastic and benign disorders.
  • Spleen is a common site of extramedullary hematopoiesis.
  • Extramedullary hematopoiesis seen in non-neoplastic conditions can occasionally be extensive and raise concerns for a myeloid neoplasm.
  • We compared the morphologic and immunohistochemical features of splenic hematopoietic proliferations seen in neoplastic myeloid disorders (eg chronic myeloproliferative disorders, myelodysplastic/myeloproliferative disorders and acute myeloid leukemias) to extramedullary hematopoiesis seen in a variety of reactive conditions.
  • In all, 80 spleen specimens were reviewed.
  • Post-bone marrow transplant and thrombotic thrombocytopenic purpura/hemolytic-uremic syndrome spleens showed extramedullary hematopoiesis with some morphologic features of immaturity, which could simulate chronic myeloproliferative disorder.
  • [MeSH-major] Bone Marrow / pathology. Bone Marrow Neoplasms / pathology. Hematopoiesis, Extramedullary. Myeloproliferative Disorders / pathology. Spleen / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Biomarkers, Tumor / metabolism. Cell Proliferation. Child. Child, Preschool. Humans. Middle Aged

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  • (PMID = 16118626.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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9. Valbuena JR, Levenback C, Mansfield P, Liu J: Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature. Ann Diagn Pathol; 2005 Oct;9(5):289-92
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  • [Title] Angiosarcoma of the spleen clinically presenting as metastatic ovarian cancer. A case report and review of the literature.
  • Primary angiosarcomas of the spleen are rare and almost always fatal.
  • The mean age of patients at presentation is 59 years and the major clinical findings include abdominal pain, splenic rupture, and splenomegaly.
  • Grossly, this neoplasm appears as hemorrhagic and/or cystic nodules, with a low-density signal seen on computed tomographic scans.
  • Histologically, the tumor is characterized by neoplastic proliferation with diffuse or focal areas of a vasoformative component with cavernous and arborizing channels.
  • The differential diagnosis includes a variety of benign and malignant vascular proliferations (littoral cell angioma and Kaposi's sarcoma) as well as metastatic tumors.
  • The worst prognostic factor is splenic rupture with early metastasis.
  • We report a case of the 43-year-old woman with a long-standing history of recurrent ovarian carcinoma treated with surgery and multiple courses of radiation therapy and chemotherapy who clinically appeared to have a metastatic ovarian cancer to the spleen and treated with partial resection of stomach and splenectomy.
  • However, histopathologic examination of the specimen showed the tumor to be of a primary angiosarcoma.
  • We believe that the lengthy exposure to radiation may have played a role in the histopathogenesis of this neoplasm in this patient.
  • [MeSH-major] Hemangiosarcoma / pathology. Neoplasms, Second Primary / pathology. Ovarian Neoplasms / pathology. Splenic Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans


10. Shintaku M, Arimoto A, Sakita N: Serous cystadenocarcinoma of the pancreas. Pathol Int; 2005 Jul;55(7):436-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The tumor extensively involved the body and tail of the pancreas and contiguously invaded the spleen.
  • The histopathology of the tumor was similar to that of serous cystadenoma, but mild nuclear hyperchromatism and atypism were noted, and the neoplastic invasion of nerve fibers in the stroma was observed.
  • In the spleen neoplastic cells forming microcysts were diffusely insinuated in the red pulp without the fibrous stroma.
  • The present case is the second example of this kind of neoplasm that showed direct splenic invasion.
  • Because serous cystadenocarcinoma of the pancreas exhibits bland cytological features, diligent search for the invasion of the surrounding tissue or peripheral nerves is needed for the differentiation from its benign counterpart.
  • [MeSH-minor] Aged. Aged, 80 and over. CA-125 Antigen / analysis. CA-19-9 Antigen. Carcinoembryonic Antigen / analysis. Humans. Immunohistochemistry. Matrix Metalloproteinase 1 / analysis. Tumor Suppressor Protein p53 / analysis

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  • (PMID = 15982220.001).
  • [ISSN] 1320-5463
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / CA-125 Antigen; 0 / CA-19-9 Antigen; 0 / Carcinoembryonic Antigen; 0 / Tumor Suppressor Protein p53; EC 3.4.24.7 / Matrix Metalloproteinase 1
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11. Duffield AS, Jarrar P, Shum C, Ahuja N, Yeo CJ, Sokoll LJ: Retroperitoneal masses with associated human chorionic gonadotropin production: Report of two cases. Clin Chim Acta; 2008 Sep;395(1-2):166-9
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  • RESULTS: The retroperitoneal masses were identified as a benign epidermoid cyst and pancreatic ductal adenocarcinoma.
  • The serum hCG concentration of the patient with the splenic epidermiod cyst decreased upon resection of the mass, and immunohistochemical staining demonstrated that the cyst lining expressed hCG.
  • Additional testing suggested that a different form of hCG was produced by each neoplasm.
  • CONCLUSIONS: hCG secretion may be associated with both benign and malignant neoplasms.
  • [MeSH-major] Carcinoma, Pancreatic Ductal / blood. Chorionic Gonadotropin / blood. Epidermal Cyst / blood. Liver Neoplasms / blood. Neoplasm Recurrence, Local / blood. Pancreatic Neoplasms / blood. Retroperitoneal Neoplasms / blood
  • [MeSH-minor] Adult. Biomarkers, Tumor / blood. Biomarkers, Tumor / secretion. Fatal Outcome. Female. Humans. Immunohistochemistry. Lymphatic Metastasis

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  • (PMID = 18505680.001).
  • [ISSN] 0009-8981
  • [Journal-full-title] Clinica chimica acta; international journal of clinical chemistry
  • [ISO-abbreviation] Clin. Chim. Acta
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Chorionic Gonadotropin
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12. Cordobès J, Molina FX, Alvarez-Segurado C, Pagán A, Salinas R, García-Sanz M, Soro JA: [Giant epidermoid splenic cyst]. Cir Esp; 2005 Jul;78(1):55-7
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  • [Title] [Giant epidermoid splenic cyst].
  • Giant epidermoid splenic cysts are rare benign tumors.
  • We report the case of a young woman with a giant epidermoid cyst, which required open total splenectomy, and review the literature on benign congenital tumors of the spleen.
  • [MeSH-major] Epidermal Cyst / surgery. Splenic Diseases / surgery
  • [MeSH-minor] Adult. Female. Humans. Neoplasm Staging. Splenectomy. Tomography, X-Ray Computed

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  • (PMID = 16420793.001).
  • [ISSN] 0009-739X
  • [Journal-full-title] Cirugía española
  • [ISO-abbreviation] Cir Esp
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Spain
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15. Lee JH, Ross WA, Davila R, Chang G, Lin E, Dekovich A, Davila M: Self-expandable metal stents (SEMS) can serve as a bridge to surgery or as a definitive therapy in patients with an advanced stage of cancer: clinical experience of a tertiary cancer center. Dig Dis Sci; 2010 Dec;55(12):3530-6
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  • BACKGROUND: Self-expandable metal stents (SEMS) can be used to relieve benign and malignant colorectal obstruction.
  • The locations of the obstruction were as follows: two in the ascending colon, one in the hepatic flexure, three in the transverse colon, two in the splenic flexure, two in the descending colon, 26 in the sigmoid colon, and ten in the rectum.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Colon, Sigmoid / pathology. Colorectal Neoplasms / complications. Colorectal Neoplasms / pathology. Constriction, Pathologic. Female. Fluoroscopy. Foreign-Body Migration / epidemiology. Humans. Male. Middle Aged. Neoplasm Staging. Palliative Care. Prosthesis Design. Retrospective Studies. Young Adult

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  • (PMID = 20721627.001).
  • [ISSN] 1573-2568
  • [Journal-full-title] Digestive diseases and sciences
  • [ISO-abbreviation] Dig. Dis. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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16. Litster AL, Sorenmo KU: Characterisation of the signalment, clinical and survival characteristics of 41 cats with mast cell neoplasia. J Feline Med Surg; 2006 Jun;8(3):177-83
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  • [Title] Characterisation of the signalment, clinical and survival characteristics of 41 cats with mast cell neoplasia.
  • While the primary splenic form of the disease is far less common, it is usually associated with more severe clinical signs.
  • Signalment, clinical and survival characteristics of mast cell neoplasia were characterised in 41 cats.
  • The most common tumour location was cutaneous/subcutaneous head and trunk.
  • Stage 1a was the most common tumour stage at first diagnosis (n=20), followed by stage 4 (both stage 4a and stage 4b; n=10).
  • Of 22 cats that underwent excisional biopsy, mast cell neoplasia recurred in four cats during the study period.
  • Three of the 41 cats presented with simultaneous cutaneous and either splenic or lymph node tumours.
  • A comparison between cats with only cutaneous tumours (n=30) and those with tumours involving the spleen or lymph nodes (n=11) showed longer survival times for the cutaneous-only group (P=0.031).
  • Twelve of the 41 cats died of mast cell neoplasia during the study period.
  • When a subgroup of cats with only cutaneous tumours (no lymph node or visceral involvement) were divided according to whether there were multiple (five or more) tumours (n=6) or a single tumour (n=19), cats with single tumours survived longer than those with multiple tumours (P=0.001).
  • Solitary cutaneous feline MCTs without spread to the lymph nodes usually manifest as benign disease with a relatively protracted course.
  • However, multiple cutaneous tumours, recurrent tumours and primary splenic disease should receive a guarded prognosis due to the relatively short median survival times associated with these forms of the disease.
  • [MeSH-minor] Animals. Cats. Disease-Free Survival. Follow-Up Studies. Neoplasm Staging. Prognosis. Severity of Illness Index. Survival Analysis

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  • (PMID = 16476559.001).
  • [ISSN] 1098-612X
  • [Journal-full-title] Journal of feline medicine and surgery
  • [ISO-abbreviation] J. Feline Med. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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17. Hori S, Nara S, Shimada K, Ojima H, Kanai Y, Hiraoka N: Serous cystic neoplasm in an intrapancreatic accessory spleen. Pathol Int; 2010 Oct;60(10):681-4
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  • [Title] Serous cystic neoplasm in an intrapancreatic accessory spleen.
  • Serous cystic neoplasm (SCN) of the pancreas is a benign epithelial neoplasm, except in extremely rare malignant cases.
  • Here we present the first reported case of SCN in an intrapancreatic accessory spleen (IPAS).
  • Pathologically the 25-mm solid mass was an IPAS showing proliferation of clear cuboidal tumor cells without atypia, forming numerous small cysts.
  • The tumor cells were rich in cytoplasmic glycogen and distributed in the splenic tissue almost diffusely.
  • Immunohistochemically, tumor cells were positive for cytokeratins, MUC6, and neuron-specific enolase, and negative for neuroendocrine markers.
  • This tumor is suggested to develop as a VHL-associated SCN from coexisting pancreatic tissue in IPAS rather than as a metastatic tumor.
  • [MeSH-major] Choristoma / pathology. Cystadenoma, Serous / pathology. Pancreatic Diseases / pathology. Spleen. von Hippel-Lindau Disease / pathology

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  • [Copyright] © 2010 The Authors. Pathology International © 2010 Japanese Society of Pathology and Blackwell Publishing Asia Pty Ltd.
  • [ErratumIn] Pathol Int. 2010 Dec;60(12):798
  • (PMID = 20846266.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Australia
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18. Teh SH, Tseng D, Sheppard BC: Laparoscopic and open distal pancreatic resection for benign pancreatic disease. J Gastrointest Surg; 2007 Sep;11(9):1120-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic and open distal pancreatic resection for benign pancreatic disease.
  • The aim of the study is to provide comparisons of the perioperative outcomes between open and laparoscopic distal pancreatic resection (DPR) for benign pancreatic disease.
  • From 2002 and 2005, there were 28 patients (16 open, 12 laparoscopic) with a mean age of 52 who had presumptive diagnoses of benign pancreatic lesions.
  • Pathology was neuroendocrine tumor (nine and five), mucinous cystic neoplasm (three and three), symptomatic pancreatic pseudocyst (two and two), and others (two and two).
  • The mean operative time was 278 vs 212 min (p = 0.05), the estimated blood lost was 609 vs 193 ml (p = 0.01), and the success rate of preoperative intent for splenic preservation was 17 vs 62% (p = 0.08) in the open and laparoscopic groups, respectively.
  • In centers with the appropriate expertise, laparoscopic DPR should be considered the procedure of choice for putative benign lesions of the pancreatic body and tail.

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  • (PMID = 17623260.001).
  • [ISSN] 1091-255X
  • [Journal-full-title] Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
  • [ISO-abbreviation] J. Gastrointest. Surg.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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19. Brosseuk D, Oosthuizen J, Pinchbeck M: Initial experience with a general population colorectal cancer screening clinic. Am J Surg; 2006 May;191(5):669-72
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  • Colorectal cancer is, therefore, an ideal malignancy for preventative screening given the presence of a benign precursor.
  • Those patients found to have adenomas or carcinomas were analyzed further regarding location of neoplasm and pathologic findings.
  • Of the 67 patients with neoplasms, 50 were left of the splenic flexure, 11 were right of the splenic flexure, and 5 patients had lesions both proximal and distal to the flexure.
  • Thirty-two of the 67 patients had complete colonoscopy at the initial procedure and, thus far, 21 patients have had completion colonoscopies, of which 9 patients had further neoplasms identified beyond the splenic flexure.
  • All 3 patients with carcinoma had early tumors resected with curative intent, with negative margins and negative nodes.
  • [MeSH-major] Cancer Care Facilities. Colonoscopy. Colorectal Neoplasms / diagnosis. Mass Screening / methods
  • [MeSH-minor] Aged. Aged, 80 and over. British Columbia / epidemiology. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies. Risk Factors. Video Recording


20. Pugliese R, Maggioni D, Sansonna F, Scandroglio I, Forgione A, Boniardi M, Costanzi A, Citterio D, Ferrari GC, Lernia SD, Magistro C: Laparoscopic distal pancreatectomy: a retrospective review of 14 cases. Surg Laparosc Endosc Percutan Tech; 2008 Jun;18(3):254-9
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  • Although the role of minimally invasive techniques in pancreatic surgery remains controversial, resection of the left pancreas for benign or endocrine lesions has been universally adopted as a routine technique over the last few years.
  • This study was undertaken to assess feasibility and safety of minimal access resections of distal pancreas in benign, endocrine, and malignant diseases.
  • Operative time, conversion rate, adequacy of dissection, respect for oncologic principles, morbidity rate, and short-term outcomes were analyzed.
  • From the years 2002 to 2007, 14 patients affected by pancreatic neoplasm of body/tail region were approached by minimally invasive technique.
  • Five patients were affected by endocrine neoplasms; distal pancreatectomy with preservation of spleen and splenic vessels was achieved laparoscopically in 3, whereas 2 needed conversion to laparotomy.

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  • (PMID = 18574411.001).
  • [ISSN] 1530-4515
  • [Journal-full-title] Surgical laparoscopy, endoscopy & percutaneous techniques
  • [ISO-abbreviation] Surg Laparosc Endosc Percutan Tech
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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21. Lin CH, Yu JC, Shih ML, Peng YJ, Hsieh CB: Littoral cell angioma of the spleen in a patient with hepatocellular carcinoma. J Formos Med Assoc; 2005 Apr;104(4):282-5
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  • [Title] Littoral cell angioma of the spleen in a patient with hepatocellular carcinoma.
  • Littoral cell angioma (LCA) is a rare primitive vascular tumor of the spleen which is benign and usually associated with visceral malignancy.
  • The diagnosis of LCA is based on histologic and immunohistologic analysis.
  • Dynamic computed tomography studies showed splenomegaly (20 cm in long axis) with a hypodense tumor in the upper pole and a contrast-enhanced hepatic mass in the right lobe of the liver.
  • Under the impression of hepatocellular carcinoma (HCC) and splenic tumor, partial hepatectomy and splenectomy were performed.
  • Histopathology showed a moderately differentiated HCC of the liver and splenic angioma with dilated vascular channels lined by plump endothelial cells.
  • Immunohistochemical staining of the splenic tumor showed focal positive reaction for factor VIII and CD68.
  • LCA of the spleen was diagnosed.

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  • (PMID = 15909068.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
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22. Sahm M, Pross M, Schubert D, Lippert H: Laparoscopic distal pancreatic resection: our own experience in the treatment of solid tumors. Surg Today; 2009;39(12):1103-8
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  • [Title] Laparoscopic distal pancreatic resection: our own experience in the treatment of solid tumors.
  • A laparoscopic resection is a new treatment for pancreatic tumors.
  • Articles by surgeons who are writing about their first experience in carrying out this treatment have appeared in the literature, reporting that laparoscopic surgery can be used for the treatment of pancreatitis, benign lesions, and solid tumors.
  • This is a study of three patients with pancreatic tumors who were treated by means of a laparoscopic distal pancreatic resection with preservation of the spleen and splenic vessels.
  • In three cases a laparoscopic distal resection was performed for the tumor.
  • A laparoscopic resection of the distal pancreas is a new alternative for the treatment of pancreatic tumors.
  • [MeSH-minor] Biopsy, Needle. Female. Follow-Up Studies. Hemostasis, Surgical / methods. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Minimally Invasive Surgical Procedures / methods. Neoplasm Invasiveness / pathology. Neoplasm Staging. Risk Assessment. Sampling Studies. Tomography, X-Ray Computed. Treatment Outcome. Ultrasonography, Doppler

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  • (PMID = 19997811.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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23. Rana N, Ming Z, Hui MS, Bin Y: Case Report: Littoral cell angioma of spleen. Indian J Radiol Imaging; 2009 Jul-Sep;19(3):210-2
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  • [Title] Case Report: Littoral cell angioma of spleen.
  • Littoral cell angioma is a rare primary vascular neoplasm of the spleen, composed of littoral cells that line the splenic sinuses of the red pulp.
  • It was thought to be a benign, incidental lesion.
  • The definitive diagnosis can only be made after histology and immunohistochemistry studies.

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  • (PMID = 19881088.001).
  • [ISSN] 1998-3808
  • [Journal-full-title] The Indian journal of radiology & imaging
  • [ISO-abbreviation] Indian J Radiol Imaging
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2766879
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24. Ivancić M, Long F, Seiler GS: Contrast harmonic ultrasonography of splenic masses and associated liver nodules in dogs. J Am Vet Med Assoc; 2009 Jan 1;234(1):88-94
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  • [Title] Contrast harmonic ultrasonography of splenic masses and associated liver nodules in dogs.
  • OBJECTIVE: To determine whether contrast harmonic ultrasonography (CHUS) can be used in dogs to distinguish splenic hemangiosarcoma from hematoma and to accurately detect and characterize liver nodules.
  • ANIMALS: 20 dogs with a splenic mass.
  • PROCEDURES: Routine abdominal ultrasonography was followed by CHUS of hepatic and splenic lesions.
  • Quantitative evaluation included peak mean pixel intensity, interval to peak intensity, area under the curve (spleen), and liver-to-lesion intensity ratio (liver).
  • RESULTS: Histologic evaluation of the spleen was performed in 19 dogs, resulting in diagnoses of hemangiosarcoma (n=11), hematoma (7), and undifferentiated sarcoma (1).
  • Benign and malignant processes in the spleen were indistinguishable via CHUS.
  • Histologic evaluation of the liver was performed in 18 dogs, resulting in a diagnosis of hemangiosarcoma in 5 dogs.
  • None of the dogs with splenic hematomas had evidence of hepatic lesions by means of conventional or contrast ultrasonography, and none had histologic evidence of liver metastases.
  • In 3 of 18 dogs, isoenhancing liver nodules were detected and all were histologically benign.
  • CONCLUSIONS AND CLINICAL RELEVANCE: Contrast harmonic ultrasonography was a noninvasive and accurate means of differentiating metastatic versus benign hepatic disease in dogs with splenic hemangiosarcoma but was not useful in distinguishing splenic hemangiosarcoma from hematoma.
  • [MeSH-major] Dog Diseases / ultrasonography. Hemangiosarcoma / veterinary. Hematoma / veterinary. Liver Neoplasms / veterinary. Splenic Neoplasms / veterinary. Ultrasonography / veterinary
  • [MeSH-minor] Animals. Contrast Media. Cross-Sectional Studies. Diagnosis, Differential. Dogs. Female. Male. Neoplasm Metastasis. Sensitivity and Specificity. Splenic Diseases / pathology. Splenic Diseases / ultrasonography. Splenic Diseases / veterinary

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  • (PMID = 19119970.001).
  • [ISSN] 0003-1488
  • [Journal-full-title] Journal of the American Veterinary Medical Association
  • [ISO-abbreviation] J. Am. Vet. Med. Assoc.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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25. Hartmann M, Marx A, Geissinger E, Müller-Hermelink HK, Rüdiger T: [Vascular proliferations of the spleen]. Pathologe; 2008 Mar;29(2):129-35
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  • [Title] [Vascular proliferations of the spleen].
  • Vascular proliferations of the spleen reflect the variability of vascular structures occurring in the normal spleen.
  • Besides haemangiomas, there is a spleen-specific vascular neoplasm, littoral cell angioma, that often occurs as a paraneoplastic lesion and thus may require the differential diagnostic delineation of metastases to the spleen in patients with known neoplasms.
  • The most common malignant vascular tumours of the spleen are angiosarcomas.
  • A recently described vascular lesion of unknown pathogenesis, sclerosing angiomatoid nodular transformation (SANT) of the spleen, usually is an incidental finding detected in the course of imaging studies.
  • [MeSH-major] Hemangioma / pathology. Hemangiosarcoma / pathology. Spleen / blood supply. Splenic Neoplasms / pathology
  • [MeSH-minor] Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Hamartoma / pathology. Histiocytoma, Benign Fibrous / pathology. Humans. Lymphangioma / pathology. Paraneoplastic Syndromes / pathology. Vascular Diseases / pathology

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  • (PMID = 18214485.001).
  • [ISSN] 1432-1963
  • [Journal-full-title] Der Pathologe
  • [ISO-abbreviation] Pathologe
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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26. Matsumoto T, Hirano S, Yada K, Shibata K, Sasaki A, Kamimura T, Ohta M, Kitano S, Kashima K: Malignant serous cystic neoplasm of the pancreas: report of a case and review of the literature. J Clin Gastroenterol; 2005 Mar;39(3):253-6
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  • [Title] Malignant serous cystic neoplasm of the pancreas: report of a case and review of the literature.
  • BACKGROUND: In general, serous cystic neoplasms of the pancreas are thought to be benign.
  • Malignant serous cystic neoplasm of the pancreas is a rare clinical entity.
  • CASE REPORT: We report the case of an 87-year-old woman with a serous microcystic neoplasm in the tail of the pancreas that behaved in a malignant fashion.
  • The neoplasm had also invaded the colonic mesentery and splenic hilum.
  • The pancreatic lesion was diagnosed as a large malignant serous cystic neoplasm, and the patient underwent distal pancreatectomy with splenectomy and segmental colectomy.
  • The resected specimen contained a large tumor, 12 x 9 x 8 cm, which occupied the body and tail of the pancreas.
  • Histologically, the tumor was indistinguishable from serous cystadenoma.
  • However, the tumor had invaded surrounding tissues including the splenic vein, and there were splenic invasion and a regional lymph node metastasis.
  • DISCUSSION: There are few reported cases of malignant serous cystic neoplasm, in which malignancy was histologically confirmed in the resected specimen.
  • There are no reports of a negative outcome with complete resection of the tumor.

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  • (PMID = 15718870.001).
  • [ISSN] 0192-0790
  • [Journal-full-title] Journal of clinical gastroenterology
  • [ISO-abbreviation] J. Clin. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 23
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27. Chung SH, Park YS, Jo YJ, Kim SH, Jun DW, Son BK, Jung JY, Baek DH, Kim DH, Jung YY, Lee WM: Asymptomatic lymphangioma involving the spleen and retroperitoneum in adults. World J Gastroenterol; 2009 Nov 28;15(44):5620-3
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  • [Title] Asymptomatic lymphangioma involving the spleen and retroperitoneum in adults.
  • Lymphangioma, a benign neoplasm of the lymphatic system, is common in children but rare in adults.
  • We report a cystic lymphangioma of the spleen and retroperitoneum, which was incidentally found in a 56-year-old man who was hospitalized due to a colon mass.
  • Abdominal CT revealed a 5.7 cm, non-enhanced multilobulated cystic mass with multiple septa in the spleen and a 10 cm lobulated cystic mass in the paraaortic area.
  • The endothelium of splenic and retroperitoneal cyst was immunohistochemically stained with D2-40 antibody.
  • The patient was finally diagnosed with splenic cystic and retroperitoneal cavernous lymphangioma.
  • [MeSH-major] Lymphangioma / diagnosis. Retroperitoneal Neoplasms / diagnosis. Retroperitoneal Space / pathology. Spleen / pathology

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  • (PMID = 19938204.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2785067
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28. Kang CM, Kim HG, Kim KS, Choi JS, Lee WJ, Kim BR: Laparoscopic distal pancreatectomy for solid pseudopapillary neoplasm of the pancreas-report of two cases. Hepatogastroenterology; 2007 Jun;54(76):1053-6
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  • [Title] Laparoscopic distal pancreatectomy for solid pseudopapillary neoplasm of the pancreas-report of two cases.
  • Solid pseudopapillary neoplasm of the pancreas is a rare pathologic entity.
  • We present two cases of laparoscopic distal pancreatectomy in female patients of incidentally found pancreatic solid pseudopapapillary neoplasm, with review of disease and technical aspect.
  • They underwent laparoscopic distal pancreatectomy with and without preservation of splenic vessels and spleen respectively.
  • This minimal invasive surgery can be safely applied to benign or low-grade malignant tumor of the pancreas especially in young and female patients.

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  • (PMID = 17629037.001).
  • [ISSN] 0172-6390
  • [Journal-full-title] Hepato-gastroenterology
  • [ISO-abbreviation] Hepatogastroenterology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
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29. Ooi BS, Quah HM, Fu CW, Eu KW: Laparoscopic high anterior resection with natural orifice specimen extraction (NOSE) for early rectal cancer. Tech Coloproctol; 2009 Mar;13(1):61-4
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  • Pneumoperitoneum was created, followed by medial-tolateral mobilization of the sigmoid colon, and take down of the splenic flexure and division of the inferior mesenteric vessels laparoscopically.
  • The upper rectum distal to the tumour and proximal colon was transected with a laparoscopic stapler.
  • This procedure may be applicable to benign tumours and early colorectal cancer, and serves as an intermediate step between laparoscopic and natural orifice surgery.
  • [MeSH-minor] Anastomosis, Surgical. Colonoscopy. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Staging

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  • (PMID = 19288243.001).
  • [ISSN] 1128-045X
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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30. Wang YJ, Li F, Cao F, Sun JB, Liu JF, Wang YH: Littoral cell angioma of the spleen. Asian J Surg; 2009 Jul;32(3):167-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Littoral cell angioma of the spleen.
  • Littoral cell angioma (LCA) is a rare primary benign vascular neoplasm of the spleen.
  • Computed tomography (CT) and ultrasound (US) imaging studies showed multiple lesions in the spleen and gallbladder stones.
  • The tumour was removed successfully by laparoscopic splenectomy and simultaneously cholecystectomy was conducted for gallbladder stones.
  • The tumour lining cells were positive for CD31/CD68 markers, and negative for CD34.

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  • (PMID = 19656757.001).
  • [ISSN] 0219-3108
  • [Journal-full-title] Asian journal of surgery
  • [ISO-abbreviation] Asian J Surg
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
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31. Mabrut JY, Fernandez-Cruz L, Azagra JS, Bassi C, Delvaux G, Weerts J, Fabre JM, Boulez J, Baulieux J, Peix JL, Gigot JF, Hepatobiliary and Pancreatic Section (HBPS) of the Royal Belgian Society of Surgery, Belgian Group for Endoscopic Surgery (BGES), Club Coelio: Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery; 2005 Jun;137(6):597-605
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Detailed questionnaires were used, focusing on patients, tumors, operative data, and late outcome.
  • Final diagnoses included benign pancreatic diseases in 111 patients (87%; insulinoma: 22, neuroendocrine neoplasm: 20, mucinous cystadenoma: 26, serous cystadenoma: 21, chronic pancreatitis: 11, others: 11), and 16 patients (13%) had malignant pancreatic diseases (insulinoma: 3, neuroendocrine neoplasm: 5, ductal adenocarcinoma: 4, cystadenocarcinoma: 2, renal metastases: 2).
  • Five patients with presumed benign pancreatic disease had malignancy at final pathology.
  • The median tumor size was 30 mm (range, 5-120 mm); 89% of tumors were located in the left pancreas.
  • Laparoscopically successful procedures included 21 enucleations, 24 distal splenopancreatectomies, 58 distal pancreatectomies with splenic preservation, and 3 pancreatoduodenal resections.
  • The overall conversion rate was 14%.
  • The rate of overall postoperative pancreatic-related complications was 31%, including a 17% rate of clinical pancreatic fistula.
  • The surgical reoperation rate was 6.3%.
  • During a median follow-up of 15 months (range, 3-47 months), 23% of the patients with pancreatic malignancies had tumor recurrence.
  • Late outcome was satisfactory in all patients with benign diseases.
  • CONCLUSIONS: LPR is feasible and safe in selected patients with presumed benign and distal pancreatic tumors.
  • [MeSH-minor] Follow-Up Studies. Humans. Length of Stay. Neoplasm Recurrence, Local. Reoperation. Retrospective Studies. Treatment Outcome

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  • (PMID = 15962401.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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32. Hutchinson CB, Canlas K, Evans JA, Obando JV, Waugh M: Endoscopic ultrasound-guided fine needle aspiration biopsy of the intrapancreatic accessory spleen: a report of 2 cases. Acta Cytol; 2010 May-Jun;54(3):337-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endoscopic ultrasound-guided fine needle aspiration biopsy of the intrapancreatic accessory spleen: a report of 2 cases.
  • BACKGROUND: Intrapancreatic accessory spleen (IPAS) can pose a challenge in the diagnostic workup by mimicking a pancreatic neoplasm.
  • Reports of IPAS identified by endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) are scant in the literature, and increased recognition of this benign entity may reduce misdiagnosis and unnecessary surgical intervention.
  • In both cases, the cytomorphologic appearance of smears and cell blocks demonstrated aggregates of benign splenic tissue characteristic of both white and red pulp.
  • One cell block demonstrated benign splenic and pancreatic parenchyma immediately adjacent to one another without an apparent intervening capsule.
  • Definitive tissue diagnosis in these 2 cases avoided not only unnecessary surgical intervention but also the need for consideration of a "watch and wait" strategy with further imaging and possible additional biopsy attempts.
  • [MeSH-major] Choristoma / diagnosis. Pancreatic Diseases / diagnosis. Spleen
  • [MeSH-minor] Adenocarcinoma / diagnosis. Antigens, CD / metabolism. Biomarkers / metabolism. Biopsy, Fine-Needle. Diagnosis, Differential. Endocrine Gland Neoplasms / diagnosis. Endosonography. Female. Humans. Male. Middle Aged. Pancreatic Neoplasms / diagnosis

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  • (PMID = 20518423.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Biomarkers
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33. Bamboat ZM, Masiakos PT: Sclerosing angiomatoid nodular transformation of the spleen in an adolescent with chronic abdominal pain. J Pediatr Surg; 2010 Jul;45(7):E13-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sclerosing angiomatoid nodular transformation of the spleen in an adolescent with chronic abdominal pain.
  • Sclerosing angiomatoid nodular transformation (SANT) is a relatively new, benign neoplasm arising within the red pulp of the spleen.
  • The lesion is often identified incidentally on imaging, and the diagnosis is confirmed on pathologic assessment of the resected spleen.
  • [MeSH-major] Abdominal Pain / etiology. Neoplasms, Vascular Tissue / pathology. Splenic Neoplasms / pathology

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20638509.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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34. Ruiz-Molina JM, Ochoa-Sánchez EP, López-Basave HN, Barrera-Franco JL, Crocifoglio-Vincenzo A, Medina-Castro JM: [Open splenectomy: ten-year experience in an oncological referral center]. Cir Cir; 2007 May-Jun;75(3):163-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Esplenectomía a cielo abierto. Experiencia de 10 años en un centro oncológico.
  • We undertook this study to evaluate open splenectomy morbidity and mortality at the Instituto Nacional de Cancerologia in Mexico City.
  • METHODS: We reviewed the clinical files of patients with benign and malignant hematological diseases, as well as other diseases, who underwent splenectomy from 1994 to 2005.
  • Average surgical time was 125 min, bleeding 485 ml, spleen weight 1553.6 g and mean size 15 x 11 x 12 cm.
  • During an average 81-month follow-up we found 14 patients (56%) asymptomatic, two patients (8%) with documented tumoral activity (angiosarcoma and non-Hodgkin's lymphoma) and one patient (4%) developed a second neoplasm.
  • CONCLUSIONS: With a spleen >1500 g, open surgery offers better visibility and, in fact, less morbidity and mortality.
  • [MeSH-major] Hematologic Diseases / surgery. Splenectomy / methods. Splenic Diseases / surgery

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  • (PMID = 17659166.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugía y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Mexico
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35. Nakamura Y, Uchida E, Nomura T, Aimoto T, Matsumoto S, Tajiri T: Laparoscopic pancreatic resection: some benefits of evolving surgical techniques. J Hepatobiliary Pancreat Surg; 2009;16(6):741-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Laparoscopic pancreatic resection began to be reported in the first half of the 1990s, with subsequent reports focusing primarily on the safety and usefulness of laparoscopic distal pancreatectomy (Lap-DP) for benign and low-malignancy lesions of the pancreatic body and tail (such as chronic pancreatitis, neuroendocrine tumor, mucinous cystic neoplasm, and intraductal papillary mucinous neoplasm).
  • [MeSH-minor] Humans. Medical Illustration. Pancreaticoduodenectomy / methods. Pancreaticoduodenectomy / trends. Splenic Artery / surgery. Splenic Vein / surgery

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  • (PMID = 19585074.001).
  • [ISSN] 1436-0691
  • [Journal-full-title] Journal of hepato-biliary-pancreatic surgery
  • [ISO-abbreviation] J Hepatobiliary Pancreat Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
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36. Tee M, Vos P, Zetler P, Wiseman SM: Incidental littoral cell angioma of the spleen. World J Surg Oncol; 2008;6:87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Incidental littoral cell angioma of the spleen.
  • BACKGROUND: Littoral cell angioma (LCA) is a recently described primary vascular neoplasm of the spleen that may be associated with other malignancies and may itself also have malignant potential.
  • This vascular neoplasm was evaluated by ultrasound, CT, MRI, Tc-99m labelled red blood cell scintigraphy, and core biopsy.
  • Following this case presentation, clinical, radiographic, and pathological features of LCA will be reviewed as well as recent advances in our understanding of this uncommon splenic lesion.
  • CONCLUSION: LCA is a rare, generally benign, primary vascular tumour of the spleen that typically is discovered incidentally.
  • Individuals diagnosed with this tumour must be carefully evaluated to exclude primary, secondary, and synchronous malignancies.
  • [MeSH-major] Hemangioma / diagnosis. Splenic Neoplasms / diagnosis
  • [MeSH-minor] Cholecystectomy. Colic / surgery. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18713469.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2527567
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37. Yazici P, Aydin U, Ersin S, Kaplan H: Hamartoma - a rare benign tumor of the spleen: a report of four cases. Eurasian J Med; 2008 Apr;40(1):48-51
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hamartoma - a rare benign tumor of the spleen: a report of four cases.
  • Splenic hamartoma is an uncommon benign tumor.
  • We retrospectively analyzed all patients who underwent splenectomy between May 2000 and June 2006 and four cases of splenic hamartoma were encountered.
  • Abdominal ultrasonography was the first diagnostic step, which revealed a splenic mass.
  • Splenic hamartoma must be considered in the differential diagnosis of splenic masses unrelated to any other malignancy.

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  • (PMID = 25610025.001).
  • [ISSN] 1308-8734
  • [Journal-full-title] The Eurasian journal of medicine
  • [ISO-abbreviation] Eurasian J Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC4261320
  • [Keywords] NOTNLM ; Hamartoma / Splenectomy / Splenic mass
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