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Items 1 to 67 of about 67
1. Auerbach A, Fanburg-Smith JC, Wang G, Rushing EJ: Focal myositis: a clinicopathologic study of 115 cases of an intramuscular mass-like reactive process. Am J Surg Pathol; 2009 Jul;33(7):1016-24
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Focal myositis is an uncommon inflammatory pseudotumor of skeletal muscle that can be confused with a variety of neoplastic and inflammatory diseases.
  • It is often misunderstood because it presents as a tumor-like mass, but histologically resembles a skeletal muscle myopathy or dystrophy.
  • Masses that ranged in size from 1.0 to 20.0 cm (median 3.0 cm, mean 3.9 cm) were reported in specific muscles of the lower extremities (including vastus lateralis, adductor muscle, and groin muscles, n=39; gastrocnemius, n=22), followed by the trunk, neck (mentalis, n=8; sternocleidomastoid muscle, n=8), and upper extremity.
  • Major histocompatibility complex-1 and weak IgG4 were focally positive in skeletal muscle.
  • S100 was strongest in skeletal muscle fibers with vacuolar change.
  • Clinical diagnostic considerations ranged from benign entities such as rhabdomyoma, intramuscular lipoma, fibromatosis, myositis ossificans, proliferative myositis, inflammatory myofibroblastic tumor, and inflammatory myopathy to malignant entities such as rhabdomyosarcoma, leiomyosarcoma, liposarcoma, and lymphoma.
  • CONCLUSIONS: Focal myositis occurs in specific muscle groups of young adults of both sexes without significant trauma.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Female. Genes, T-Cell Receptor. Humans. Immunoglobulin Heavy Chains / genetics. Immunohistochemistry. In Situ Hybridization. Male. Middle Aged. Muscle, Skeletal / pathology. Polymerase Chain Reaction. Young Adult

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  • (PMID = 19363438.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Immunoglobulin Heavy Chains
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2. Ioannou M, Papanastassiou J, Athanassiou AE, Ziras N, Kottakis S, Demertzis N: Surgical options in cases of tumorous destruction of the proximal humerus: twenty-one patients followed from 4-9 years. J BUON; 2009 Jan-Mar;14(1):57-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PURPOSE: To compare the postoperative outcomes of several techniques of reconstructive surgery for malignant and aggressive benign tumors of the proximal humerus.
  • PATIENTS AND METHODS: Twenty-one shoulder reconstructions following tumor resection were studied.
  • Nine cases with an intracompartmental tumor were treated with endoprosthetic reconstruction.
  • Three cases with the tumor involving the glenoid were treated with a typical Malawer VB shoulder girdle resection.
  • In 5 patients with extracompartmental resections including the rotator cuff or the deltoid muscle a modified Tikhoff-Linberg procedure using polypropylene mesh was performed.
  • In 4 patients with extracompartmental excision the authors proceeded to skeletal reconstruction using a modular endoprosthesis, while soft tissue reconstruction was undertaken using monofilament polypropylene mesh in order to enforce joint stability.

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  • (PMID = 19373948.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Greece
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3. Le Corroller T, Kovacs TJ, Champsaur P: Nodular fasciitis with cortical involvement. Joint Bone Spine; 2009 Jan;76(1):101-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Nodular fasciitis is a commonly encountered benign soft-tissue fibrous tumor that typically involves the upper extremity and may be mistaken for a sarcomatous lesion because of its rapid growth.
  • [MeSH-major] Fasciitis / diagnosis. Muscle, Skeletal / pathology

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  • (PMID = 18993101.001).
  • [ISSN] 1778-7254
  • [Journal-full-title] Joint, bone, spine : revue du rhumatisme
  • [ISO-abbreviation] Joint Bone Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] France
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4. Moosavi C, Jha P, Fanburg-Smith JC: An update on plexiform fibrohistiocytic tumor and addition of 66 new cases from the Armed Forces Institute of Pathology, in honor of Franz M. Enzinger, MD. Ann Diagn Pathol; 2007 Oct;11(5):313-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An update on plexiform fibrohistiocytic tumor and addition of 66 new cases from the Armed Forces Institute of Pathology, in honor of Franz M. Enzinger, MD.
  • The seminal article of Drs Franz Enzinger and Renyuan Zhang in 1988 defined plexiform fibrohistiocytic tumor (PFHT) as a distinctive entity.
  • Although most cases were observed at the dermal/subcutaneous interface, 22 cases were predominantly dermal, and the rest predominantly subcutaneous, with 4 superficially involving skeletal muscle.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Skin Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 17870015.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD; 0 / Antigens, Differentiation, Myelomonocytic; 0 / CD68 antigen, human
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5. Mete O, Rotstein L, Asa SL: Controversies in thyroid pathology: thyroid capsule invasion and extrathyroidal extension. Ann Surg Oncol; 2010 Feb;17(2):386-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Controversies surrounding diagnostic criteria that distinguish benign from malignant thyroid follicular lesions have been brought to the attention of this community.
  • Moreover, the presence of adipose tissue within the thyroid gland and its pseudocapsule implies that thyroid tumor within fat tissue cannot be accepted as a criterion of ETE by that thyroid carcinoma.
  • While invasion of skeletal muscle is a more reliable feature of ETE, at the isthmus, these fibers can be normally present within the gland, and this criterion does not have value.
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Staging. Prognosis. Thyroid Gland / anatomy & histology

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  • (PMID = 19949881.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
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6. Helbig D, Simon JC, Wetzig T, Paasch U: [Desmoplastic fibroma on arm of 22-year-old woman]. Hautarzt; 2010 Oct;61(10):885-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Desmoplastic fibroblastoma ("collagenous fibroma") is a rare benign, slowly progressive fibrous soft tissue tumor that ranges 1-20 cm in size.
  • The tumor occurs in all ages, predominantly in the upper part of the body.
  • The tumor often infiltrates the subcutis; less often it invades the fascia and skeletal muscle or causes bone erosions.
  • Histologically, the tumor is composed of spindle-shaped cells embedded in a densely collagenous stroma, sometimes forming a pseudo-capsule.
  • Magnetic resonance imaging and computed tomography as well as ultrasonography are used to define the extensions of the tumor.
  • Because it is clinically extremely difficult to determine if soft tissue tumors are benign or malignant, all should be excised with a margin of safety and examined histologically.
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy. Female. Fibroblasts / pathology. Humans. Young Adult

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  • [Cites] Pediatr Dev Pathol. 1999 Jan-Feb;2(1):62-4 [9841708.001]
  • [Cites] Arch Pathol Lab Med. 1998 May;122(5):455-60 [9593348.001]
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  • (PMID = 20082062.001).
  • [ISSN] 1432-1173
  • [Journal-full-title] Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete
  • [ISO-abbreviation] Hautarzt
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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7. Monson E, Vancourt R, Dawson J: Myxoinflammatory fibroblastic sarcoma: a case report and review of the literature. J Foot Ankle Surg; 2010 Jan-Feb;49(1):86.e1-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The majority of soft tissue masses seen in the lower extremity are benign tumors caused by degenerative, reactive, or inflammatory processes.
  • This is a rare tumor that predominately involves the distal extremities.
  • It often presents as a painless mass within the subcutaneous tissue and can easily be confused with benign lesions.
  • A high rate of local recurrence means patients must be followed up closely after resection of the tumor.
  • [MeSH-minor] Amputation. Humans. Leg. Male. Middle Aged. Muscle, Skeletal / pathology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / surgery. Postoperative Complications. Surgical Flaps

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  • [Copyright] Copyright 2010 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20123295.001).
  • [ISSN] 1542-2224
  • [Journal-full-title] The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
  • [ISO-abbreviation] J Foot Ankle Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 8
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8. Patsiaoura K, Anagnostou E, Benis N: Intramuscular myxoma of the nasal vestibule. Auris Nasus Larynx; 2010 Feb;37(1):100-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Intramuscular myxoma is an uncommon benign soft tissue neoplasm and a distinct histopathological entity within the heterogeneous group of myxomas.
  • The tumor was surgically removed and the patient is free of recurrence or complications 8 months after treatment.
  • To the very best of our knowledge, there is no report of this neoplasm located within the nasal and oral mimetic muscles.
  • [MeSH-major] Muscle, Skeletal / pathology. Myxoma / pathology. Paranasal Sinus Neoplasms / pathology

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  • [Copyright] Copyright (c) 2009 Elsevier Ireland Ltd. All rights reserved.
  • (PMID = 19414229.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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9. Cymet-Ramírez J, Martínez-Flores LM, Villalobos Garduño FE: [Lipoblastoma. A case report]. Acta Ortop Mex; 2007 May-Jun;21(3):151-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Lipoblastoma is an rare benign tumors of infancy of fetal adipose tissue, that usually affect infants and children less than 3 years of age.
  • The tumor was completely excised surgically.
  • [MeSH-minor] Child, Preschool. Humans. Incidental Findings. Magnetic Resonance Imaging. Male. Muscle, Skeletal / pathology. Neoplasm Invasiveness

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  • (PMID = 17937179.001).
  • [ISSN] 2306-4102
  • [Journal-full-title] Acta ortopédica mexicana
  • [ISO-abbreviation] Acta Ortop Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
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10. Schulman FY, Johnson TO, Facemire PR, Fanburg-Smith JC: Feline peripheral nerve sheath tumors: histologic, immunohistochemical, and clinicopathologic correlation (59 tumors in 53 cats). Vet Pathol; 2009 Nov;46(6):1166-80
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All of the tumors involved skin, subcutis, skeletal muscle, and/or mucous membranes.
  • Immunohistochemically, all tumors were positive for vimentin and S-100 protein, 44 of 59 were positive for glial fibrillary acidic protein (GFAP), and all were negative for muscle specific actin.
  • The tumors fell into 3 histologic categories: 34 benign tumors with Antoni A areas that were S-100 protein and GFAP positive, 9 benign tumors that lacked Antoni A areas and were S-100 protein positive and GFAP negative, and 16 tumors with features of malignancy.
  • Tumor recurrence was reported for all 3 of the histologic subtypes.

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  • (PMID = 19605904.001).
  • [ISSN] 1544-2217
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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11. Feyma T, Carter GT, Weiss MD: Myotonic dystrophy type 1 coexisting with myasthenia gravis and thymoma. Muscle Nerve; 2008 Jul;38(1):916-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Myotonic dystrophy type 1 (DM1) is an autosomal-dominant multisystemic disorder that may rarely be associated with benign and malignant neoplasms.
  • Due to somatic instability, which has been shown previously in DM1, the myotonin protein kinase (DMPK) gene appears to act as a tumor suppressor.
  • [MeSH-minor] Action Potentials / physiology. DNA Repeat Expansion / genetics. Diplopia / pathology. Diplopia / physiopathology. Electromyography. Electrophysiology. Humans. Male. Middle Aged. Motor Neurons / pathology. Motor Neurons / physiology. Muscle Fibers, Skeletal / pathology. Muscle Fibers, Skeletal / physiology. Myotonin-Protein Kinase. Oculomotor Muscles / pathology. Oculomotor Muscles / physiopathology. Protein-Serine-Threonine Kinases / genetics. Protein-Serine-Threonine Kinases / metabolism. Receptors, Cholinergic / biosynthesis. Receptors, Cholinergic / genetics


12. Jo JH, Lee JH, Kim DC, Kim SH, Kwon HC, Kim JS, Kim HJ: A case of benign metastasizing leiomyoma with multiple metastasis to the soft tissue, skeletal muscle, lung and breast. Korean J Intern Med; 2006 Sep;21(3):199-201
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A case of benign metastasizing leiomyoma with multiple metastasis to the soft tissue, skeletal muscle, lung and breast.
  • Benign metastasizing leiomyoma (BML) is composed of well-differentiated smooth muscle cells and dense connective tissue.
  • BML affects middle-aged women who have had previous hysterectomies due to a histologically benign-appearing uterine leiomyoma.
  • We report here on a case of BML from the uterine leiomyoma in a 39-year-old woman that involved the soft tissues, skeletal muscles, lungs and breasts.
  • The microscopic findings of the breast and lung tumor were similar to those of the benign uterine leiomyoma.
  • We report here on a rare case of benign metastasizing uterine leiomyoma that involved the soft tissue, skeletal muscles, lungs and breasts, and we include a review of the relevant literature.
  • [MeSH-major] Breast Neoplasms / secondary. Leiomyoma / pathology. Lung Neoplasms / secondary. Muscle Neoplasms / secondary. Soft Tissue Neoplasms / secondary. Uterine Neoplasms / pathology
  • [MeSH-minor] Adult. Antineoplastic Agents / therapeutic use. Female. Humans. Hysterectomy. Muscle, Skeletal / pathology. Tamoxifen / therapeutic use

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  • [Cites] Clin Chest Med. 2004 Jun;25(2):343-60 [15099894.001]
  • [Cites] AJR Am J Roentgenol. 1976 Sep;127(3):441-6 [183531.001]
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  • (PMID = 17017672.001).
  • [ISSN] 1226-3303
  • [Journal-full-title] The Korean journal of internal medicine
  • [ISO-abbreviation] Korean J. Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 094ZI81Y45 / Tamoxifen
  • [Other-IDs] NLM/ PMC3890726
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13. McKenney JK: An approach to the classification of spindle cell proliferations in the urinary bladder. Adv Anat Pathol; 2005 Nov;12(6):312-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Spindle cell proliferations of the urinary bladder are uncommon but may cause significant diagnostic difficulty resulting from the degree of morphologic overlap between clinically benign and malignant lesions.
  • This review discusses the nomenclature, morphologic criteria, and immunohistochemical features used to classify spindle cell proliferations occurring in the urinary bladder, including those with myofibroblastic, smooth muscle, skeletal muscle, epithelial (sarcomatoid urothelial carcinoma), fibroblastic, and neural differentiation.
  • [MeSH-major] Neoplasms, Muscle Tissue / classification. Neoplasms, Muscle Tissue / pathology. Urinary Bladder Neoplasms / classification. Urinary Bladder Neoplasms / pathology
  • [MeSH-minor] Animals. Biomarkers, Tumor / analysis. Carcinoma / chemistry. Carcinoma / classification. Carcinoma / pathology. Fibroma / chemistry. Fibroma / classification. Fibroma / pathology. Humans. Immunohistochemistry. Neurofibroma / chemistry. Neurofibroma / classification. Neurofibroma / pathology. Terminology as Topic

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  • (PMID = 16330928.001).
  • [ISSN] 1072-4109
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 67
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14. Semenova LA, Bulycheva IV: [Chondromyxoid fibroma]. Arkh Patol; 2007 Mar-Apr;69(2):37-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Chondromyxoid fibroma is a benign chondroid tissue tumor characterized by the lobular overgrowth of stellate or elongated cells in the myxoid or chondroid intracellular matrix.
  • They may be encountered in any skeletal bones, mainly at the age of 20-30 years.
  • A positive reaction with S-100 protein, d smooth muscle actin, and CD 34 was immunohistochemically detected in chondromyxoid fibroma tissue.
  • Recurrence of the tumor is observed in 15% of the surgically treated cases.

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  • (PMID = 17642191.001).
  • [ISSN] 0004-1955
  • [Journal-full-title] Arkhiv patologii
  • [ISO-abbreviation] Arkh. Patol.
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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15. Jha P, Moosavi C, Fanburg-Smith JC: Giant cell fibroblastoma: an update and addition of 86 new cases from the Armed Forces Institute of Pathology, in honor of Dr. Franz M. Enzinger. Ann Diagn Pathol; 2007 Apr;11(2):81-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All cases had benign behavior, but almost half recurred.
  • The caveat was mistaking this tumor for a malignancy.
  • They proposed a relationship of this childhood tumor to dermatofibrosarcoma protuberans (DFSP).
  • Most cases were dermal and subcutaneous, 3 purely dermal, and 5 involved superficial skeletal muscle.
  • Two cases of pure GCF recurred as a hybrid tumor with DFSP areas, one of these with hypercellular DFSP.
  • Most cases studied were positive for CD34 (more intense in DFSP than relatively hypocellular GCF areas) and negative for smooth muscle actin, desmin, HMB-45, keratin, and S100 protein.
  • Additional observations of marked perivascular and onionskin-like chronic inflammation and consistent hemorrhage may aid in the diagnosis of this previously well-described tumor.
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / metabolism. Child. Child, Preschool. Female. History, 20th Century. Humans. Infant. Male. Middle Aged. Neoplasm Recurrence, Local / pathology. Registries

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  • (PMID = 17349565.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Biography; Historical Article; Journal Article; Portraits
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Personal-name-as-subject] Enzinger FM
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16. Singh A, Pandey KC, Pant NK: Cavitary mucoepidermoid carcinoma of lung with metastases in skeletal muscles as presenting features: a case report and review of the literature. J Cancer Res Ther; 2010 Jul-Sep;6(3):350-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cavitary mucoepidermoid carcinoma of lung with metastases in skeletal muscles as presenting features: a case report and review of the literature.
  • Initially described as a benign adenoma, it is now considered to be a malignant epithelial tumor.
  • Here, we report a case of MEC of lung with metastases to skeletal muscles of thigh and arm.
  • [MeSH-major] Carcinoma, Mucoepidermoid / diagnosis. Lung Neoplasms / diagnosis. Muscle Neoplasms / secondary. Muscle, Skeletal / pathology

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  • (PMID = 21119274.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
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17. Hausbrandt PA, Leithner A, Beham A, Bodo K, Raith J, Windhager R: A rare case of infantile myofibromatosis and review of literature. J Pediatr Orthop B; 2010 Jan;19(1):122-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Infantile myofibromatosis is a rare benign tumor-disease (1/400,000).
  • Radiographic films and ultrasound examination presented a pretibial soft-tissue tumor mass with calcifications and two osteolytic lesions with a sclerotic rim.
  • A skeletal survey showed more osteolytic lesions, but the magnetic resonance imaging showed no more soft-tissue lesions.
  • Infantile myofibromatosis is a very rare benign tumor-disease.
  • Histopathologically, cells characteristically appear as spindle-shaped fibroblast cells with pale pink cytoplasm and elongated nuclei and the immunophenotype is defined with a positive reaction on smooth-muscle antigen vimentin and the muscle-specific antigen HHF-35.
  • However, a thorough examination has to be carried out to exclude lesion in other organs like gastro-intestinal or cardio-pulmonary nodular tumor masses.
  • [MeSH-minor] Calcinosis / pathology. Calcinosis / physiopathology. Diagnosis, Differential. Follow-Up Studies. Frozen Sections. Histiocytosis, Langerhans-Cell / diagnosis. Humans. Infant. Male. Neoplasm Regression, Spontaneous


18. Bekler H, Gokce A, Beyzadeoglu T: Chondroid syringoma of the hand: a rare localization. Handchir Mikrochir Plast Chir; 2007 Dec;39(6):430-2
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  • Chondroid syringoma is a rare benign neoplasm of the sweat glands that usually occurs in the head and neck region.
  • We describe a 18-year-old male patient with a benign chondroid syringoma that occurred at an unusual site, leading to compression symptoms of the ulnar nerve causing symptoms at the hypothenar region of the right hand.
  • Although it is a rare tumor at an unusual site, it should be included in the differential diagnosis of the hand tumors.
  • [MeSH-minor] Adolescent. Biopsy. Humans. Image Enhancement. Magnetic Resonance Imaging. Male. Muscle, Skeletal / pathology. Neoplasm Invasiveness

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  • (PMID = 18058676.001).
  • [ISSN] 0722-1819
  • [Journal-full-title] Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen
  • [ISO-abbreviation] Handchir Mikrochir Plast Chir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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19. Cyran CC, Fu Y, Raatschen HJ, Rogut V, Chaopathomkul B, Shames DM, Wendland MF, Yeh BM, Brasch RC: New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues. J Magn Reson Imaging; 2008 Mar;27(3):581-9
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  • [Title] New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues.
  • 100 cm(3)) and tumor fractional plasma volumes (%) based on a two-compartment kinetic model were performed for skeletal muscle and tumors.
  • 100 cm(3)) in normal soft tissue microvessels allowing successful differentiation (P < 0.05) of cancers from normal muscle.
  • PEG(12,000)-Gen4-(Gd-DOTA) leaked in tumors and in normal muscle (K(PS) = 51 +/- 26 and K(PS) = 21 +/- 18 microL/min .
  • The apparent threshold in effective molecular weight for a clear differentiation of cancer from normal muscle with no measurable leak in the muscle is between 194 and 323 kDa.
  • [MeSH-minor] Animals. Breast Neoplasms / diagnosis. Endothelium, Vascular. Female. Humans. Neoplasm Transplantation. Rats. Rats, Nude. Transplantation, Heterologous

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  • (PMID = 18219614.001).
  • [ISSN] 1053-1807
  • [Journal-full-title] Journal of magnetic resonance imaging : JMRI
  • [ISO-abbreviation] J Magn Reson Imaging
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA 082923; United States / NCI NIH HHS / CA / R01 CA 103850
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 0 / Heterocyclic Compounds; 0 / Organometallic Compounds; 92923-44-9 / gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; AU0V1LM3JT / Gadolinium
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20. Falavigna A, Righesso O, Volquind D, Teles AR: Intramuscular myxoma of the cervical paraspinal muscle. Eur Spine J; 2009 Jul;18 Suppl 2:245-9
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  • [Title] Intramuscular myxoma of the cervical paraspinal muscle.
  • Myxoma is a neoplasm of mesenchymal origin composed of undifferentiated stellate cells in a myxoid stroma.
  • This tumor can develop in a variety of locations.
  • Myxomas that arise from skeletal muscles are called intramuscular myxomas.
  • They usually occur in large skeletal muscles.
  • Only ten cases of these benign tumors involving the neck muscles were reported in literature.
  • Tumor total removal was performed through normal muscle margins and the vertebral periosteum was scraped.
  • The tumor was encapsulated, lobulated with a gray-white appearance.
  • Despite its benign characteristics, local recurrence was reported after subtotal resection.
  • Tumor total removal should be the goal of surgery.
  • [MeSH-major] Cervical Vertebrae. Muscle Neoplasms / diagnosis. Muscle, Skeletal. Myxoma / diagnosis

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  • (PMID = 19301043.001).
  • [ISSN] 1432-0932
  • [Journal-full-title] European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
  • [ISO-abbreviation] Eur Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
  • [Other-IDs] NLM/ PMC2899565
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21. Ryś J, Kruczak A, Marczyk E, Skotnicki P, Moskal J, Ambicka A, Harazin-Lechowska A, Wasilewska A, Vogelgesang M, Dyczek S: Primary soft tissue giant cell tumour of the neck. Cytological and histological characteristics of the tumour and differential diagnosis. Pol J Pathol; 2009;60(2):98-104; quiz 105
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  • Giant cell tumour of soft part is a very rare neoplasm.
  • That is why we report a case of primary giant cell tumour of soft part localized in the trapezius muscle of a 19-year-old woman.
  • We present both cytological and histological picture of the neoplasm.
  • [MeSH-major] Giant Cell Tumors / pathology. Head and Neck Neoplasms / pathology. Muscle, Skeletal / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Osteosarcoma / diagnosis. Sarcoma, Synovial / diagnosis. Synovitis, Pigmented Villonodular / diagnosis. Treatment Outcome. Young Adult

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  • (PMID = 19886185.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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22. Kajihara M, Sugawara Y, Sakayama K, Kikuchi K, Mochizuki T, Murase K: Evaluation of tumor blood flow in musculoskeletal lesions: dynamic contrast-enhanced MR imaging and its possibility when monitoring the response to preoperative chemotherapy-work in progress. Radiat Med; 2007 Apr;25(3):94-105
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  • [Title] Evaluation of tumor blood flow in musculoskeletal lesions: dynamic contrast-enhanced MR imaging and its possibility when monitoring the response to preoperative chemotherapy-work in progress.
  • PURPOSE: The objective of this study was to calculate tumor blood flow (TBF) in musculoskeletal lesions and to evaluate the usefulness of this parameter in differentiating malignant from benign lesions and monitoring the treatment response to preoperative chemotherapy.
  • RESULTS: TBF ranged from 2.7 to 178.6 mL/100 mL/min in benign lesions and from 15.4 to 296.3 mL/100 mL/min in malignant lesions.
  • SS ranged from 0.5%/s to 31.8%/s for benign lesions and from 3.1%/s to 64.8%/sec for malignant lesions.
  • TBF and SS did not differ significantly between benign and malignant lesions.
  • Among the nine patients who underwent preoperative chemotherapy, TBF after chemotherapy was lower in good responders (11.7, 11.0, 7.9 mL/100 mL/min) (n = 3, tumor necrosis > or =90%) than in poor responders (23.4-141.5 mL/100 mL/min) (n = 6, tumor necrosis <90%).
  • CONCLUSION: TBF and SS cannot reliably differentiate malignant from benign lesions.
  • [MeSH-major] Bone Neoplasms / blood supply. Contrast Media / administration & dosage. Gadolinium DTPA / administration & dosage. Magnetic Resonance Imaging / methods. Muscle Neoplasms / blood supply

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  • (PMID = 17450333.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Contrast Media; K2I13DR72L / Gadolinium DTPA
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23. Juhlin J, Eiholm S: [Rhabdomyoma in the head and neck region]. Ugeskr Laeger; 2009 Mar 30;171(14):1194
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  • Extracardiac rhabdomyoma is an extremely uncommon benign neoplasm with skeletal muscle differentiation which usually involves the head and neck region.

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  • (PMID = 19338741.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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24. Lokeshwar VB, Cerwinka WH, Lokeshwar BL: HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion. Cancer Res; 2005 Mar 15;65(6):2243-50
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  • [Title] HYAL1 hyaluronidase: a molecular determinant of bladder tumor growth and invasion.
  • Hyaluronic acid promotes tumor progression; however, the functions of hyaluronidase in cancer are largely unknown.
  • Whereas HYAL1-S and vector tumors infiltrated skeletal muscle and blood vessels, HYAL1-AS tumors resembled benign neoplasia.
  • HYAL1-S and vector tumors expressed significantly higher amounts of HYAL1 (in tumor cells) and hyaluronic acid (in tumor-associated stroma) than HYAL1-AS tumors.
  • These results show that HYAL1 expression in bladder cancer cells regulates tumor growth and progression and therefore serves as a marker for high-grade bladder cancer.
  • [MeSH-minor] Apoptosis / physiology. Cell Cycle / physiology. Cell Growth Processes / physiology. Cell Line, Tumor. Extracellular Matrix / metabolism. Humans. Hyaluronic Acid / metabolism. Neoplasm Invasiveness. Neoplasm Transplantation. Neovascularization, Pathologic / enzymology. Neovascularization, Pathologic / pathology. Transfection. Transplantation, Heterologous

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  • (PMID = 15781637.001).
  • [ISSN] 0008-5472
  • [Journal-full-title] Cancer research
  • [ISO-abbreviation] Cancer Res.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01 CA 072821-06A2
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 9004-61-9 / Hyaluronic Acid; EC 3.2.1.35 / Hyaluronoglucosaminidase
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25. Osipov V, Carrera GF: Collagenous fibroma (desmoplastic fibroblastoma) with vertebral body erosion. Sarcoma; 2009;2009:682687
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  • Collagenous fibroma (desmoplastic fibroblastoma) is a recently described rare benign tumor affecting mainly males in the fifth through seventh decades.
  • This tumor occurs predominantly in the peripheral sites, with predilection for upper and lower extremities.
  • The patients present with a painless mass of involving subcutis, with one quarter of all cases involving skeletal muscle.
  • This tumor should be in the differential diagnosis of the soft tissue lesions presenting with bony erosion.

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  • (PMID = 19503798.001).
  • [ISSN] 1357-714X
  • [Journal-full-title] Sarcoma
  • [ISO-abbreviation] Sarcoma
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Egypt
  • [Other-IDs] NLM/ PMC2688648
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26. Mandal RV, Duncan LM, Austen WG Jr, Nielsen GP: Infiltrating intramuscular spindle cell lipoma of the face. J Cutan Pathol; 2009 Oct;36 Suppl 1:70-3
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  • Spindle cell lipoma is a benign lipomatous tumor, which usually arises on the back of the neck, shoulder or upper back of males in the third to seventh decade of life.
  • Histologically, a proliferation of mature adipocytes, ropey collagen fibers and spindle cells within a myxoid stroma was present in the subcutaneous tissue and infiltrated between skeletal muscle fibers.
  • [MeSH-major] Lipoma / pathology. Neoplasm Recurrence, Local / pathology. Nose Neoplasms / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 19187113.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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27. Yang J, Frassica FJ, Fayad L, Clark DP, Weber KL: Analysis of nondiagnostic results after image-guided needle biopsies of musculoskeletal lesions. Clin Orthop Relat Res; 2010 Nov;468(11):3103-11
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  • Malignant tumors had a higher IC rate than benign tumors (5% vs. 0%); fibromyxoid sarcoma and rare subtypes of osteosarcoma had higher IC rates than other diagnoses.
  • We believe these biopsies appropriate in selected circumstances but a key factor for appropriate use is an experienced musculoskeletal tumor team with frequent communication to correlate clinical, radiographic, and histologic information for each patient.
  • [MeSH-major] Biopsy, Fine-Needle / methods. Bone Neoplasms / pathology. Muscle Neoplasms / pathology. Radiography, Interventional. Tomography, X-Ray Computed. Ultrasonography, Interventional

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  • (PMID = 20383617.001).
  • [ISSN] 1528-1132
  • [Journal-full-title] Clinical orthopaedics and related research
  • [ISO-abbreviation] Clin. Orthop. Relat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
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28. Manna AK, Chattopadhyay A, Chowdhury K, Chowdhury MK, Dutta SK: Chondroid lipoma--a case report. Indian J Pathol Microbiol; 2006 Jul;49(3):422-4
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  • Chondroid lipoma is a rare fatty tumor of soft tissues, especially in limbs and limb girdles.
  • Though it is clinically benign, the main importance lies in its histological similarity with myxoid liposarcoma and chondrosarcoma, which have poorer prognosis.
  • [MeSH-major] Chondrosarcoma / pathology. Lipoma / pathology. Muscle Neoplasms / pathology. Thigh
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Muscle, Skeletal / pathology

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  • (PMID = 17001908.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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29. Chiang ER, Chen TH: Multiple glomus tumors in gastrocnemius muscle: a case report. Arch Orthop Trauma Surg; 2008 Jan;128(1):29-31
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  • [Title] Multiple glomus tumors in gastrocnemius muscle: a case report.
  • Glomus tumors are rare benign tumors that account 1-5% of soft tissue tumors of the hand.
  • We describe an unusual case of recurrent glomus tumor located in lower leg.
  • [MeSH-major] Glomus Tumor / diagnosis. Muscle Neoplasms / diagnosis. Muscle, Skeletal. Neoplasm Recurrence, Local / diagnosis

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  • (PMID = 17624538.001).
  • [ISSN] 0936-8051
  • [Journal-full-title] Archives of orthopaedic and trauma surgery
  • [ISO-abbreviation] Arch Orthop Trauma Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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30. McNab PM, DeMers NM, Schlauder S, Morgan M, Nasir A, Coppola D, Bui MM: Potential utility of CD5 immunohistochemical staining in the diagnosis of muscle tumors. Ann Clin Lab Sci; 2009;39(2):108-13
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  • [Title] Potential utility of CD5 immunohistochemical staining in the diagnosis of muscle tumors.
  • This pilot study evaluated CD5 expression in benign and malignant muscle tumors in comparison to normal muscle.
  • In some of these cases, non-neoplastic smooth muscle (10) and skeletal muscle (6) were identified adjacent to tumors.
  • In addition, 3 cases were retrieved for non-neoplastic smooth muscle tissue that was unrelated to any tumor.
  • CD5 was strongly and diffusely expressed in non-neoplastic skeletal (6/6) and smooth (10/10) muscle adjacent to tumor.
  • CD5 was also strongly and diffusely expressed in 3 cases of smooth muscle tissue not adjacent to tumor.
  • Leiomyomas (10/10) were CD5 positive but showed variable intensity within the same tumor.
  • In conclusion, this pilot study suggests that CD5 staining may be used to differentiate benign muscle tissue from malignancy.
  • Albeit our case series is limited, this study indicates potential utility of CD5 staining in diagnosis of muscle tumors.
  • [MeSH-major] Antigens, CD5 / analysis. Muscle Neoplasms / diagnosis. Muscle Neoplasms / pathology. Sarcoma / diagnosis. Sarcoma / pathology
  • [MeSH-minor] Antigens, CD / analysis. Humans. Immunohistochemistry. Leiomyoma / pathology. Leiomyosarcoma / pathology. Muscle, Skeletal / cytology. Muscle, Skeletal / pathology. Muscle, Smooth / cytology. Muscle, Smooth / pathology. Retrospective Studies. Rhabdomyoma / pathology. Rhabdomyosarcoma / pathology. T-Lymphocytes / pathology

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  • (PMID = 19429795.001).
  • [ISSN] 1550-8080
  • [Journal-full-title] Annals of clinical and laboratory science
  • [ISO-abbreviation] Ann. Clin. Lab. Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD5
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31. O'Callaghan MG, House M, Ebay S, Bhadelia R: Rhabdomyoma of the head and neck demonstrated by prenatal magnetic resonance imaging. J Comput Assist Tomogr; 2005 Jan-Feb;29(1):130-2
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  • This benign tumor of skeletal muscle is uncommon and should not be confused with its malignant counterpart-rhabdomyosarcoma.
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Gestational Age. Humans. Infant, Newborn. Neoplasm Recurrence, Local / pathology. Pregnancy. Ultrasonography, Prenatal


32. Pichi B, Manciocco V, Marchesi P, Pellini R, Ruscito P, Vidiri A, Covello R, Spriano G: Rhabdomyoma of the parapharyngeal space presenting with dysphagia. Dysphagia; 2008 Jun;23(2):202-4
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  • Rhabdomyoma is an exceedingly rare soft tissue benign tumor of skeletal muscle origin classified into cardiac and extracardiac types based on location.
  • Adult rhabdomyomas are rare, but morphologically characteristic, benign mesenchymal tumors with mature skeletal muscle differentiation that in 90% of cases arise in the head and neck region, mainly in the mucosa of the oropharynx, nasopharynx, and larynx, from the branchial musculature of third and fourth branchial arches.

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  • [ISSN] 0179-051X
  • [Journal-full-title] Dysphagia
  • [ISO-abbreviation] Dysphagia
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33. Widmann G, Riedl A, Schoepf D, Glodny B, Peer S, Gruber H: State-of-the-art HR-US imaging findings of the most frequent musculoskeletal soft-tissue tumors. Skeletal Radiol; 2009 Jul;38(7):637-49
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  • The aim of this review is to provide sonographic findings of the most frequent benign and malign soft-tissue lesions.
  • By this essay, we can show that combined with clinical features, with information on tumor-localization and patient age, many musculoskeletal lesions may be successfully characterized by HR-US.
  • [MeSH-major] Bone Neoplasms / diagnosis. Muscle Neoplasms / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 18846371.001).
  • [ISSN] 1432-2161
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 53
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34. Dobashi Y, Suzuki S, Sato E, Hamada Y, Yanagawa T, Ooi A: EGFR-dependent and independent activation of Akt/mTOR cascade in bone and soft tissue tumors. Mod Pathol; 2009 Oct;22(10):1328-40
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  • To gain the insight into the involvement of signaling mediated by the mammalian target of rapamycin (mTOR) in the phenotype and biological profiles of tumors and tumor-like lesions of the bone and soft tissue, we analyzed the expression and phosphorylation (activation) of mTOR and its correlation with the status of upstream and downstream modulator proteins Akt, p70S6-kinase (S6K), and eukaryotic initiation factor 4E-binding protein 1 (4E-BP1), which we refer to collectively as mTOR cassette proteins.
  • Immunohistochemical analysis of 140 cases showed activation of Akt in 55% (61% in malignant and 27% in benign), and mTOR expression in 61% (66% in malignant and 39% in benign).
  • The preponderance of mTOR activation was found in tumors of peripheral nerve sheath (malignant peripheral nerve sheath tumor and schwannoma), skeletal muscle origin (rhabdomyosarcoma), and in those exhibiting epithelial nature (chordoma and synovial sarcoma).
  • We conclude that mTOR-mediated signaling proteins function not only in the proliferation of the tumor cells, but also in the differentiation and/or maintenance of morphological phenotypes in tumors of rhabdomyoblastic and nerve sheath cell origin.
  • [MeSH-minor] Cell Proliferation. Enzyme Activation. Humans. Immunoblotting. Immunohistochemistry. Mutation. Neoplasm Staging. Phosphorylation. Prognosis. TOR Serine-Threonine Kinases

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  • (PMID = 19648884.001).
  • [ISSN] 1530-0285
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Adaptor Proteins, Signal Transducing; 0 / EIF4EBP1 protein, human; 0 / Phosphoproteins; EC 2.7.- / Protein Kinases; EC 2.7.1.1 / MTOR protein, human; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.10.1 / EGFR protein, human; EC 2.7.10.1 / Receptor, Epidermal Growth Factor; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt; EC 2.7.11.1 / Ribosomal Protein S6 Kinases, 70-kDa
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35. Hwang HS, Lee WJ, Lim HK, Chun HK, Ahn GH: Chondrolipoma in the pelvic cavity: a case report. Korean J Radiol; 2008 Nov-Dec;9(6):563-7
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  • A chondrolipoma is an extremely rare form of a benign mesenchymal tumor containing mature cartilage and fatty tissue.
  • Chondrolipomas may be found in almost any part of the body, particularly in the connective tissue of the breast, head and neck area, as well as in the skeletal muscle.

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  • (PMID = 19039275.001).
  • [ISSN] 1229-6929
  • [Journal-full-title] Korean journal of radiology
  • [ISO-abbreviation] Korean J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2627234
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36. Mavroudis K, Aloumanis K, Papapetrou PD, Voros D, Spanos I: Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle. Fertil Steril; 2007 Jun;87(6):1468.e13-6
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  • [Title] Virilization caused by an ectopic adrenal tumor located behind the iliopsoas muscle.
  • OBJECTIVE: Virilization due to androgen-secreting neoplasms in women is a result of androgen overproduction from benign or malignant tumors that are found in the ovaries or rarely in the adrenal glands.
  • We describe a very rare case of an ectopic androgen-producing adrenal tumor.
  • RESULT(S): An ectopic mass was detected behind the left iliopsoas muscle.
  • CONCLUSION(S): This case illustrates difficulties in detecting and localizing the rare contingence of an ectopic adrenocortical androgen-secreting tumor.
  • [MeSH-major] Adrenal Gland Neoplasms / surgery. Muscle, Skeletal. Virilism / etiology

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  • (PMID = 17368455.001).
  • [ISSN] 1556-5653
  • [Journal-full-title] Fertility and sterility
  • [ISO-abbreviation] Fertil. Steril.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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37. Fernández JM, Medlich MA, López LH, Loredo CF, Luque LC: Fetal intermediate rhabdomyoma of the lip: case report. J Clin Pediatr Dent; 2005;29(2):179-80
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  • Fetal rhabdomyoma is a rare benign neoplasm of skeletal muscle that must be distinguished histologically from various malignant lesions, including rhabdomyosarcoma.

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  • (PMID = 15719926.001).
  • [ISSN] 1053-4628
  • [Journal-full-title] The Journal of clinical pediatric dentistry
  • [ISO-abbreviation] J Clin Pediatr Dent
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Ruiz E, Pozo P, Toselli L, Fernández M, Christiansen S, Lambertini R: Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma. Urology; 2008 Jun;71(6):1067-9
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  • [Title] Unusual benign paratesticular tumor in an infant mimicking rhabdomyosarcoma.
  • A 6-month-old boy presented with an asymptomatic, right intrascrotal mass whereby the testicle was surrounded by a friable lipomatous tumor.
  • Histopathologic findings showed a juvenile xanthogranuloma, a non-Langerhans histiocytosis commonly described in infants in the skin and skeletal muscle.

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  • (PMID = 18538690.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Gajda M, Welzel C, Holzhausen HJ, Jamali Y, Schrom T, Hauptmann S, Bloching M: [Multifocal adult rhabdomyoma of the neck: a rare entity]. Otolaryngol Pol; 2005;59(6):883-6
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  • Extracardiac rhabdomyoma comprise 2% of all tumors of skeletal muscle differentiation.
  • A review of the world literature revealed about 19 acceptable cases of benign, multifocal adult-type rhabdomyoma with a distinct male predominance.
  • The pathogenesis of this benign striated muscle tumor is still unclear.
  • The differential diagnoses of rhabdomyoma in adults are myoblastoma or Abrikossof tumor, reticulohistiocytoma, rhabdomyosarcoma and hibernoma.
  • Although adult rhabdomyomas have a distinct histology, they often are mistaken for a variety of other lesions, particularly Abrikossof tumor.
  • Electron microscopic studies confirmed the tumor's myogenic origin.
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Muscle, Skeletal / pathology. Muscle, Skeletal / surgery. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery

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  • (PMID = 16521457.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 16
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40. Blacksin MF, White LM, Hameed M, Kandel R, Patterson FR, Benevenia J: Granular cell tumor of the extremity: magnetic resonance imaging characteristics with pathologic correlation. Skeletal Radiol; 2005 Oct;34(10):625-31
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  • [Title] Granular cell tumor of the extremity: magnetic resonance imaging characteristics with pathologic correlation.
  • OBJECTIVE: The purpose of this study is to delineate the magnetic resonance (MR) appearance of a granular cell tumor (GrCT) of the extremity and to correlate the imaging appearance with the microscopic findings.
  • DESIGN AND PATIENTS: A retrospective review of five patients with a histopathologic diagnosis of GrCT and pre-operative MR imaging of the neoplasm was done.
  • RESULTS: The benign subtype of GrCT is usually isointense or brighter than muscle on T1-weighted sequences, round or oval in shape, superficial in location, and 4 cm or less in size.
  • On T2-weighted sequences, benign lesions may demonstrate a high peripheral signal, as well as a central signal intensity that is isointense to muscle or suppressed fat.
  • A significant stromal component in the tumor and, hypothetically, a ribbon-like arrangement of tumor cells may influence the signal intensity demonstrated on the T1 and T2-weighted sequences.
  • CONCLUSION: Benign GrCT has imaging characteristics which may distinguish this tumor from other soft tissue neoplasms, as well as the malignant type of this tumor.
  • [MeSH-major] Foot Diseases / pathology. Granular Cell Tumor / pathology. Hand / pathology. Shoulder / pathology. Soft Tissue Neoplasms / pathology. Thigh / pathology

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  • (PMID = 16003548.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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41. Chi AC, Barnes JD, Budnick S, Agresta SV, Neville B: Rhabdomyosarcoma of the maxillary gingiva. J Periodontol; 2007 Sep;78(9):1839-45
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  • BACKGROUND: Rhabdomyosarcoma is a malignant neoplasm of primitive mesenchyme exhibiting skeletal muscle differentiation.
  • Many of the tumor cells exhibited abundant eosinophilic cytoplasm.
  • Immunohistochemical stains showed the tumor cells to be positive for desmin, myogenin, and myogenic differentiation 1 (MyoD1).
  • Pain is a variable presenting symptom, and early lesions may be mistaken for benign neoplastic, inflammatory, or infectious processes.

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  • (PMID = 17760557.001).
  • [ISSN] 0022-3492
  • [Journal-full-title] Journal of periodontology
  • [ISO-abbreviation] J. Periodontol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 51
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42. Hornick JL, Fletcher CD: Cellular neurothekeoma: detailed characterization in a series of 133 cases. Am J Surg Pathol; 2007 Mar;31(3):329-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Cellular neurothekeomas are distinctive benign cutaneous tumors of uncertain histogenesis.
  • Mean tumor size was 1.1 cm (range: 0.3 to 6 cm; 90% <2 cm).
  • In 30% of cases, neurothekeoma was suggested by the referring pathologist; the most common other diagnoses offered were plexiform fibrohistiocytic tumor, benign fibrous histiocytoma, and a low-grade sarcoma.
  • Histologically, most cases were poorly marginated; 33 (25%) infiltrated fat, and 10 (8%) entrapped skeletal muscle (all but 1 situated on the face).
  • All tumors were reactive for NKI-C3, 110/123 (89%) expressed neuron-specific enolase, 73/127 (57%) showed at least focal staining for smooth muscle actin, and only 1 was focally desmin positive.
  • Ten tumors recurred locally (7 situated on the face), after a mean of 18 months; tumor had been marginally excised or had involved excision margins in all cases with available information.
  • There is no good evidence that these lesions show nerve sheath differentiation and the nomenclature will likely change when the tumor cell lineage is better defined.
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor / analysis. Child. Child, Preschool. Diagnosis, Differential. Female. Histiocytoma, Benign Fibrous / diagnosis. Humans. Immunohistochemistry. Infant. Male. Middle Aged. Mitosis. Neoplasm Recurrence, Local. Sarcoma / diagnosis

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  • (PMID = 17325474.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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43. Donato M, Vanel D, Alberghini M, Mercuri M: Muscle fibers inside a fat tumor: a non-specific imaging finding of benignancy. Eur J Radiol; 2009 Oct;72(1):27-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Muscle fibers inside a fat tumor: a non-specific imaging finding of benignancy.
  • INTRODUCTION: The differential diagnosis between benign and low-grade well-differentiated malignant lipomatous tumors might be very difficult for both the radiologist and the pathologist, although it has practical consequences.
  • Among the criteria, muscular fibers detected inside the lesion are considered radiologically and histologically as a reliable sign of a benign intramuscular lipoma.
  • CONCLUSION: Intra lesional muscular fibers detected on imaging or histological examinations should not be considered as a completely reliable sign of a benign intramuscular lipoma.
  • In case of atypical clinical behaviour, genetic criteria should be used to prove the aggressiveness of the tumor.
  • [MeSH-major] Lipoma / diagnosis. Liposarcoma / diagnosis. Magnetic Resonance Imaging. Muscle Fibers, Skeletal / pathology. Muscle Neoplasms / diagnosis

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  • (PMID = 19608364.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Ireland
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44. Papadogeorgakis N, Petsinis V, Nikitakis N, Goutzanis L, Alexandridis C: Intramuscular myxoma of the masseter muscle. A case report. Oral Maxillofac Surg; 2009 Mar;13(1):37-40
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  • [Title] Intramuscular myxoma of the masseter muscle. A case report.
  • PURPOSE: Myxomas are benign, locally infiltrative, connective tissue tumors that rarely occur in the head and neck region.
  • The purpose of this paper is to describe a very rare case of an intramuscular myxoma of the masseter muscle.
  • After a preauricular approach, a circumscribed solid gelatinous tumor was excised with thin margins including adjacent muscle tissue.
  • [MeSH-major] Masseter Muscle / surgery. Muscle Neoplasms / surgery

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  • (PMID = 18989712.001).
  • [ISSN] 1865-1569
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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45. Miyake M, Tateishi U, Maeda T, Arai Y, Seki K, Sugimura K: Computed tomography and magnetic resonance imaging findings of soft tissue perineurioma. Radiat Med; 2008 Jul;26(6):368-71
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Soft tissue perineurioma is an uncommon benign peripheral nerve sheath tumor, although it is the most common subtype of perineuriomas.

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  • (PMID = 18677612.001).
  • [ISSN] 0288-2043
  • [Journal-full-title] Radiation medicine
  • [ISO-abbreviation] Radiat Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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46. Schrecengost JE, Tabbara S, Patterson J, Wick MR: Cutaneous mesenchymal hamartoma with mixed myogenous differentiation. J Cutan Pathol; 2006 Apr;33(4):327-30
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  • Microscopic examination of the excised specimen showed a mixture of mesenchymal elements, dominated by haphazard thin fascicles of skeletal muscle.
  • Immunohistochemistry showed positive staining for muscle-specific actin and desmin in the fascicular components of the lesion, and smooth muscle actin, desmin, and h-caldesmon positivity in a haphazard collection of muscle fibers in the deep dermis and anal submucosa.
  • Hamartomas containing skeletal muscle have rarely been reported outside of the head and neck region.
  • They must be distinguished from a variety of other tumors, including juvenile rhabdomyoma, benign Triton tumor, and rhabdomyosarcoma.
  • [MeSH-minor] Female. Humans. Infant. Muscle Fibers, Skeletal / pathology. Muscle, Skeletal / metabolism. Muscle, Skeletal / pathology

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  • (PMID = 16630187.001).
  • [ISSN] 0303-6987
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
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47. Zolota V, Tzelepi V, Charoulis N, Apostolakis E, Dougenis D: Mediastinal rhabdomyoma: case report and review of the literature. Virchows Arch; 2006 Jul;449(1):124-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Rhabdomyomas are benign tumors in which at least some cells are differentiated as skeletal muscle cells with cytoplasmic cross-striations.
  • Extracardiac adult rhabdomyoma is an extremely uncommon benign neoplasm that usually involves the head and neck region.
  • [MeSH-minor] Actins / analysis. Aged. Biomarkers, Tumor / analysis. Desmin / analysis. Disease-Free Survival. Female. Humans. Immunohistochemistry. Myoglobin / analysis. Radiography, Thoracic. Treatment Outcome

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  • (PMID = 16636850.001).
  • [ISSN] 0945-6317
  • [Journal-full-title] Virchows Archiv : an international journal of pathology
  • [ISO-abbreviation] Virchows Arch.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin; 0 / Myoglobin
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48. Hornick JL, Fletcher CD: Soft tissue perineurioma: clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol; 2005 Jul;29(7):845-58
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Perineuriomas are uncommon benign peripheral nerve sheath tumors that include soft tissue, sclerosing, and intraneural variants.
  • Tumor size ranged from 0.3 to 20 cm (mean, 4.1 cm) in greatest dimension.
  • Based on worrisome cytologic or architectural features, 14 cases were classified as atypical perineuriomas: 12 contained scattered pleomorphic cells, 1 showed an abrupt transition from typical morphology to a markedly hypercellular, fascicular area with cytologic atypia, and 1 exhibited diffuse infiltration of skeletal muscle.
  • All tumors were reactive for epithelial membrane antigen; 50 of 78 (64%) expressed CD34, 22 of 76 (29%) claudin-1, 16 of 77 (21%) smooth muscle actin, and 4 of 81 (5%) S-100 protein.
  • No tumor metastasized.
  • Soft tissue perineuriomas behave in a benign fashion and rarely recur.
  • [MeSH-minor] Adolescent. Adult. Aged. Biomarkers, Tumor. Child. Female. Humans. Immunohistochemistry. Male. Microscopy, Electron, Transmission. Middle Aged. Treatment Outcome

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  • (PMID = 15958848.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 42
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49. Uysal A, Sungur N, Koçer U, Cöloğlu H, Oruç M, Yalta T: Neuromuscular hamartoma of the occipital nerve: clinical report. J Craniofac Surg; 2005 Jul;16(4):740-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Neuromuscular hamartoma is a rare benign tumor consisted of well-differentiated striated muscle fibers within mature neural elements.
  • There have been no reports of this tumor in association with the occipital nerve.
  • [MeSH-minor] Child. Female. Humans. Muscle Fibers, Skeletal. Nerve Fibers. Neuromuscular Diseases / pathology. Neuromuscular Diseases / surgery. Occipital Bone. Scalp / innervation

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  • (PMID = 16077331.001).
  • [ISSN] 1049-2275
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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50. Kim K, Velez I, Kaltman SI, Lopez E, Stern D: Odontogenic carcinoma differentiation into rhabdomyosarcoma: report of a rare case. Quintessence Int; 2009 Nov-Dec;40(10):837-42
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • To the authors' knowledge, this is the first reported case of an odontogenic carcinoma with documented skeletal muscle differentiation (rhabdomyosarcoma).
  • The histology and clinical features of this aggressive odontogenic neoplasm are described.
  • Within the English-language literature, only 2 cases are reported of an odontogenic tumor with muscle differentiation: a benign odontogenic tumor (ameloblastoma) with differentiation into a rhabdomyosarcoma and an odontogenic sarcoma with smooth-muscle differentiation.

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  • (PMID = 19898715.001).
  • [ISSN] 1936-7163
  • [Journal-full-title] Quintessence international (Berlin, Germany : 1985)
  • [ISO-abbreviation] Quintessence Int
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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51. Barroca H, Farinha NJ, Lobo A, Monteiro J, Lopes JM: Deep-seated congenital juvenile xanthogranuloma: report of a case with emphasis on cytologic features. Acta Cytol; 2007 May-Jun;51(3):473-6
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  • BACKGROUND: Juvenile xanthogranuloma (JXG) is a rare, benign non-Langerhans cell histiocytosis that usually occurs in the head, neck or upper trunk of neonates and young children.
  • The surgical specimen histology revealed a JXG with skeletal muscle invasion.
  • Complete reexcision was performed 2 months later after regrowth of the tumor.


52. Vargas SO, Korpershoek E, Kozakewich HP, de Krijger RR, Fletcher JA, Perez-Atayde AR: Cytogenetic and p53 profiles in congenital cystic adenomatoid malformation: insights into its relationship with pleuropulmonary blastoma. Pediatr Dev Pathol; 2006 May-Jun;9(3):190-5
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  • Congenital cystic adenomatoid malformation (CCAM), a developmental anomaly of lung, shares many features with the pediatric tumor pleuropulmonary blastoma (PPB).
  • Both may show benign epithelium-lined cysts and mesenchymal proliferation, often with skeletal muscle differentiation.
  • [MeSH-major] Cystic Adenomatoid Malformation of Lung, Congenital / genetics. Cystic Adenomatoid Malformation of Lung, Congenital / metabolism. Lung Neoplasms / genetics. Lung Neoplasms / metabolism. Pulmonary Blastoma / genetics. Pulmonary Blastoma / metabolism. Tumor Suppressor Protein p53 / metabolism
  • [MeSH-minor] Child, Preschool. Cytogenetics. DNA, Neoplasm / analysis. DNA, Neoplasm / isolation & purification. Female. Humans. Immunohistochemistry. Infant. Karyotyping. Male. Polymorphism, Single-Stranded Conformational. Prospective Studies

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  • (PMID = 16944975.001).
  • [ISSN] 1093-5266
  • [Journal-full-title] Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
  • [ISO-abbreviation] Pediatr. Dev. Pathol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA, Neoplasm; 0 / Tumor Suppressor Protein p53
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53. Mercier I, Vuolo M, Jasmin JF, Medina CM, Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP, Kitsis RN: ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer. Cell Cycle; 2008 Jun 1;7(11):1640-7
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  • ARC is expressed predominantly in terminally differentiated cells such as cardiac and skeletal myocytes and neurons.
  • Recently, however, the abundance of ARC was noted to be markedly increased in the epithelium of primary human breast cancers compared with benign breast tissue and to confer chemo- and radiation-resistance.
  • In this study, we assessed the abundance and subcellular localization of ARC in 21 human colon cancer cell lines and in 44 primary human colon adenocarcinomas and adjacent benign colonic tissue.
  • Levels of ARC in the cytoplasm were increased in well, moderately, and poorly differentiated cancers compared with benign tissue, while levels of nuclear ARC were increased only in moderately differentiated tumors.
  • [MeSH-major] Adenocarcinoma / metabolism. Apoptosis Regulatory Proteins / genetics. Biomarkers, Tumor / genetics. Colonic Neoplasms / metabolism. Muscle Proteins / genetics
  • [MeSH-minor] Cell Line, Tumor. Cytoplasm / metabolism. Humans. Immunoblotting. Immunohistochemistry

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  • (PMID = 18469522.001).
  • [ISSN] 1551-4005
  • [Journal-full-title] Cell cycle (Georgetown, Tex.)
  • [ISO-abbreviation] Cell Cycle
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R01-CA-098779; United States / NCI NIH HHS / CA / R01-CA-120876; United States / NCI NIH HHS / CA / R01-CA-80250; United States / NHLBI NIH HHS / HL / R01HL60665; United States / NHLBI NIH HHS / HL / R01HL61550; United States / NHLBI NIH HHS / HL / R01HL80607
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Apoptosis Regulatory Proteins; 0 / Biomarkers, Tumor; 0 / Muscle Proteins; 0 / NOL3 protein, human
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54. Belmahi A, Ouezzani S, El Aziz S: [Efficiency of the combination of Mersilene-musculocutaneous flap in the reconstruction of full-thickness chest wall defects. A retrospective study of 14 cases]. Ann Chir Plast Esthet; 2007 Apr;52(2):96-102
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The skeletal stabilization by different synthetic materials with numerous modalities of use and the superficial coverage of the defect by a musculocutaneous flap are the two imperatives parts of this reconstruction.
  • PATIENTS AND METHODS: From January 1997 to January 2006, 14 patients, 10 males and 4 females, aged between 17 and 63 years old and suffering from full-thickness chest wall defects secondary to tumor resection have benefited from a simple reconstruction, wherever the defect, by a Mersilene Mesh and a muscular or musculocutaneous flap.
  • The histological diagnoses of these tumors were 3 chondrosarcomas, 3 sternum and 1 rib metastases, 2 desmoid tumors, 1 Ewing's sarcoma, 4 benign tumors.
  • The flaps used were pedicled in 13 cases and based on the latissimus dorsi muscle, the serratus muscle and the pectoralis major muscle; in 1 case, the latissimus dorsi musculocutaneous flap was free.
  • RESULTS: The skeletal stabilisation seems satisfying.

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  • (PMID = 17030387.001).
  • [ISSN] 0294-1260
  • [Journal-full-title] Annales de chirurgie plastique et esthétique
  • [ISO-abbreviation] Ann Chir Plast Esthet
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Polyethylene Terephthalates; 25038-59-9 / Lavsan
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55. Sakamoto A, Yoshida T, Matsuura S, Tanaka K, Matsuda S, Oda Y, Hori Y, Yokomizo A, Iwamoto Y: Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features. World J Surg Oncol; 2007;5:88
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  • [Title] Metastasis to the gluteus maximus muscle from renal cell carcinoma with special emphasis on MRI features.
  • BACKGROUND: The skeletal muscle is an unusual site for metastasis from renal cell carcinoma (RCC).
  • Metastatic RCC must be differentiated from benign primary soft-tissue tumors because aggressive surgical resection is necessary.
  • CASE PRESENTATION: We present the case of a 65-year-old man with metastatic RCC in the gluteus maximus muscle (3.8 cm in diameter) found on enhanced computed tomography (CT) 6 years after nephrectomy.
  • Because the growth of the lesion was slow, benign tumor was a differential diagnosis.
  • However, magnetic resonance imaging (MRI) showed that the mass had high-signal intensity on T1- and T2-weighted images (WIs) compared to that of skeletal muscle, with mild enhancement by Gadolinium.
  • Therefore, under a diagnosis of metastatic RCC, the lesion was resected together with the surrounding skeletal muscle.
  • CONCLUSION: MRI features of metastatic RCC may be beneficial in differentiating it from primary soft-tissue tumor.

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  • (PMID = 17683570.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1976113
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56. Grosheva M, Gerharz M, Bovenschulte H, Beutner D: [Adult multilocular rhabdomyoma as a rare cause of dysphagia]. Laryngorhinootologie; 2008 Sep;87(9):651-3
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  • BACKGROUND: Adult rhabdomyoma is a benign tumor of the cardial und skeletal muscle system.
  • CONCLUSION: Rhabdomyoma as a benign lesion could occur multilocular and simulate metastasis of a malign formation.

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  • (PMID = 18833645.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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57. Shin HJ, Amaral JG, Armstrong D, Chait PG, Temple MJ, John P, Smith CR, Taylor G, Connolly BL: Image-guided percutaneous biopsy of musculoskeletal lesions in children. Pediatr Radiol; 2007 Apr;37(4):362-9
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  • Data collected included tumor type and complication rates.
  • The diagnostic success of biopsy in primary malignant tumors was significantly higher (92%) than in primary benign tumors (65%; P=0.008).
  • [MeSH-major] Biopsy, Needle / methods. Bone Neoplasms / pathology. Muscle Neoplasms / pathology. Surgery, Computer-Assisted / methods

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58. Daigeler A, Vogt PM, Busch K, Pennekamp W, Weyhe D, Lehnhardt M, Steinstraesser L, Steinau HU, Kuhnen C: Elastofibroma dorsi--differential diagnosis in chest wall tumours. World J Surg Oncol; 2007;5:15
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  • BACKGROUND: Elastofibromas are benign soft tissue tumours mostly of the infrascapular region between the thoracic wall, the serratus anterior and the latissimus dorsi muscle with a prevalence of up to 24% in the elderly.
  • The tumor sizes ranged from 3 to 13 cm.
  • Due to its benign behaviour, the tumor should be resected only in symptomatic patients.

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  • (PMID = 17280612.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC1797045
  • [General-notes] NLM/ Original DateCompleted: 20070808
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59. Ishoo E: Intramuscular myxoma presenting as a rare posterior neck mass in a young child: case report and literature review. Arch Otolaryngol Head Neck Surg; 2007 Apr;133(4):398-401
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  • Intramuscular myxoma (IMM) is an uncommon benign tumor that presents as a slow-growing, deep-seated mass confined to the skeletal muscle.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Muscle Neoplasms / diagnosis. Myxoma / diagnosis

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  • (PMID = 17438256.001).
  • [ISSN] 0886-4470
  • [Journal-full-title] Archives of otolaryngology--head & neck surgery
  • [ISO-abbreviation] Arch. Otolaryngol. Head Neck Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 15
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60. Hamada K, Ueda T, Higuchi I, Inoue A, Tamai N, Myoi A, Tomita Y, Aozasa K, Yoshikawa H, Hatazawa J: Peripheral nerve schwannoma: two cases exhibiting increased FDG uptake in early and delayed PET imaging. Skeletal Radiol; 2005 Jan;34(1):52-7
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  • We set the maximum standardized uptake value (SUV max) with a cut-off point of 3.0 to distinguish benign and malignant lesions.
  • Although the mechanism responsible for the increased FDG uptake in benign schwannomas remains unknown, we discuss our findings in the context of tumor cellularity and briefly review other studies on the subject.
  • [MeSH-minor] Adult. Female. Follow-Up Studies. Head and Neck Neoplasms / diagnostic imaging. Humans. Muscle Neoplasms / diagnostic imaging. Retroperitoneal Neoplasms / diagnostic imaging

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  • (PMID = 15480645.001).
  • [ISSN] 0364-2348
  • [Journal-full-title] Skeletal radiology
  • [ISO-abbreviation] Skeletal Radiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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61. Joyner DE, Damron TA, Aboulafia A, Bokor W, Bastar JD, Randall RL: Heterogeneous expression of melanoma antigen (hMAGE) mRNA in mesenchymal neoplasia. Tissue Antigens; 2006 Jul;68(1):19-27
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  • In this study, hMAGEA2, hMAGEA3, hMAGEA4, and hMAGEC1 mRNA content in 21 benign mesenchymal tumors (representing seven histotypes) and 28 primary sarcomas (10 histotypes) was inventoried using real-time-PCR and then compared against hMAGE mRNA expression in non-sarcomatous malignancies, three cell lines, and muscle. hMAGEA2, hMAGEA3, and hMAGEC1 transcripts were infrequent in mesenchymal tissues in general, whereas hMAGEA4 mRNA was present in 84% of all mesenchymal tumors, 100% of non-sarcomatous tumors, all three cell lines, and in four of five muscle samples.
  • Although hMAGEA4 mRNA was detected in four of five muscle preparations, there was no indication that the mRNA was translated into protein.
  • The presence of hMAGEA4 mRNA in muscle, plus the inconsistent and infrequent occurrence of hMAGEA2, hMAGEA3, and hMAGEC1 mRNA within and among mesenchymal tumor histotypes, makes these four hMAGE antigens unlikely candidates for sarcoma-specific immunotherapy.
  • [MeSH-major] Antigens, Neoplasm / metabolism. Neoplasm Proteins / metabolism. Neoplasms / metabolism. Neoplasms, Connective Tissue / metabolism. Sarcoma / metabolism. Testis / immunology
  • [MeSH-minor] Cell Line. Cell Line, Tumor. Gene Expression. Humans. Male. Melanoma-Specific Antigens. Muscle, Skeletal / metabolism. Neoplasm Metastasis / pathology. RNA, Messenger / metabolism. RNA, Neoplasm / analysis

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  • [ErratumIn] Tissue Antigens. 2006 Aug;68(2):192
  • (PMID = 16774536.001).
  • [ISSN] 0001-2815
  • [Journal-full-title] Tissue antigens
  • [ISO-abbreviation] Tissue Antigens
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / MAGEA1 protein, human; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins; 0 / RNA, Messenger; 0 / RNA, Neoplasm
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62. Premalata CS, Kumar RV, Saleem KM, Fathima LJ, Das K: Fetal rhabdomyoma of the lower extremity. Pediatr Blood Cancer; 2009 Jul;52(7):881-3
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  • Fetal rhabdomyoma is a benign tumor of the skeletal muscle, showing varying degrees of skeletal muscle maturation.

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  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19165887.001).
  • [ISSN] 1545-5017
  • [Journal-full-title] Pediatric blood & cancer
  • [ISO-abbreviation] Pediatr Blood Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Shelekhova K, Kazakov DV, Michal M: Infiltrating retiform perineurioma: a case report. Ann Diagn Pathol; 2005 Oct;9(5):293-4
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  • Retiform perineurioma is a rare distinct histologic subtype of benign soft tissue perineurioma.
  • We report 1 case of retiform perineurioma with a superficial invasion of the adjacent skeletal muscle.
  • The patient was a 34-year-old woman with a neoplasm located between the deltoid muscle and the biceps.
  • Histologically, the tumor was nonencapsulated, composed exclusively of perineurial cells without cytologic and tissue atypia.
  • There were focal areas in which the neoplastic cells infiltrated the muscle tissue, widely separating the bundles.
  • [MeSH-minor] Adult. Female. Humans. Muscle, Skeletal / pathology

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  • (PMID = 16198959.001).
  • [ISSN] 1092-9134
  • [Journal-full-title] Annals of diagnostic pathology
  • [ISO-abbreviation] Ann Diagn Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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64. Sohn WI, Kim JH, Jung SN, Kwon H, Cho KJ: Intramuscular lipoma of the sternocleidomastoid muscle. J Craniofac Surg; 2010 Nov;21(6):1976-8
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  • [Title] Intramuscular lipoma of the sternocleidomastoid muscle.
  • Intramuscular lipoma is a rare benign mesenchymal tumor that infiltrates the skeletal muscle.
  • To our knowledge, only 4 cases of intramuscular lipoma in the sternocleidomastoid muscle have been reported in the literature.
  • In addition, although rare, concerning intramuscular lipoma that developed in the head and neck area, because important structures are present densely in a small space, it is important to establish a preoperative plan by determining the size and location of the tumor through preoperative clinical and radiologic tests.
  • We had a case of intramuscular lipoma in sternocleidomastoid muscle and resected the mass completely including a portion of attached muscles.
  • [MeSH-major] Lipoma / diagnosis. Muscle Neoplasms / diagnosis. Neck Muscles / pathology

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  • (PMID = 21119474.001).
  • [ISSN] 1536-3732
  • [Journal-full-title] The Journal of craniofacial surgery
  • [ISO-abbreviation] J Craniofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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65. Lemos MM, Karlen J, Tani E: Fine-needle aspiration cytology of angiomatoid malignant fibrous histiocytoma. Diagn Cytopathol; 2005 Aug;33(2):116-21
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  • Angiomatoid malignant fibrous histiocytoma (AMFH) is a rare, low-grade malignant mesenchymal neoplasm that affects mostly the extremities of children and young adults.
  • The tumor cells showed mild to moderate anisocariosis, often with nucleolus and vast, fragile cytoplasm.
  • [MeSH-major] Histiocytoma, Benign Fibrous / pathology. Muscle Neoplasms / pathology
  • [MeSH-minor] Adolescent. Biopsy, Fine-Needle. Cell Differentiation. Cell Nucleus / metabolism. Cell Nucleus / pathology. Child, Preschool. Female. Fibroblasts / metabolism. Fibroblasts / pathology. Humans. Myoblasts, Skeletal / metabolism. Myoblasts, Skeletal / pathology

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  • [Copyright] Copyright 2005 Wiley-Liss, Inc.
  • (PMID = 16007669.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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66. Fayad LM, Wang X, Salibi N, Barker PB, Jacobs MA, Machado AJ, Weber KL, Bluemke DA: A feasibility study of quantitative molecular characterization of musculoskeletal lesions by proton MR spectroscopy at 3 T. AJR Am J Roentgenol; 2010 Jul;195(1):W69-75
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • SUBJECTS AND METHODS: Thirty-three subjects with 34 musculoskeletal lesions (four histologically proven malignant, 13 histologically proven benign or proven benign by follow-up analysis, and 17 posttreatment fibrosis with documented stability for 6-36 months) underwent single-voxel 3-T MRS studies.
  • The choline concentrations of benign and malignant lesions were compared using the Mann-Whitney test.
  • For five benign lesions (two neurofibromas, two schwannomas, and one enchondroma), the choline concentrations were 0.11, 0.28, 0.13, 0.8, and 1.2 mmol/kg, respectively.
  • For seven benign lesions (two hematomas, two bone cysts, one lipoma, one giant cell tumor, and one pigmented villonodular synovitis), the spectra showed negligible choline content.
  • Average choline concentrations were different for malignant and benign lesions (2.7 vs 0.5 mmol/kg; p = 0.01).

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  • Hazardous Substances Data Bank. CHOLINE CHLORIDE .
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  • (PMID = 20566784.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / 1R01CA100184; United States / NCI NIH HHS / CA / CA100184-01A2; United States / Intramural NIH HHS / / ZIA CL090019-01; United States / NCI NIH HHS / CA / CA100184-03; United States / NCI NIH HHS / CA / CA100184-02; United States / NCI NIH HHS / CA / P50CA103175; United States / Intramural NIH HHS / / ZIA EB000072-01; United States / NCI NIH HHS / CA / R01 CA100184-02; United States / NCI NIH HHS / CA / P50 CA103175; United States / NCI NIH HHS / CA / R01 CA100184-03; United States / NCI NIH HHS / CA / R01 CA100184-01A2; United States / NCI NIH HHS / CA / R01 CA100184
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; 0 / Contrast Media; 0 / Protons; N91BDP6H0X / Choline
  • [Other-IDs] NLM/ NIHMS245710; NLM/ PMC3035623
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67. Watanabe H, Ishida Y, Nagashima K, Makino T, Norisugi O, Shimizu T: Desmoplastic fibroblastoma (collagenous fibroma). J Dermatol; 2008 Feb;35(2):93-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Desmoplastic fibroblastoma (DF) is a rare fibrotic tumor that has a wide anatomic distribution and it can appear in deep sections of the subcutis, in fascia, in aponeurosis or in skeletal muscles.
  • The entrapment of fat and muscle tissues was focally identified at the edges of the tumor.
  • The stellate and multinucleated cells in the lesion were strongly positive for vimentin but negative for cytokeratin, smooth muscle actin, desmin, S-100, CD34, factor XIIIa, and CD68.
  • These findings suggest that the stellate and multinucleated cells in the lesion were of fibroblastic origin and this neoplasm was pathologically benign.

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  • (PMID = 18271804.001).
  • [ISSN] 0385-2407
  • [Journal-full-title] The Journal of dermatology
  • [ISO-abbreviation] J. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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