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1. Tryka E, Skomra D, Klatka J, Gieroba R, Olszański W: [Epithelial cell proliferation in nasal polyps]. Otolaryngol Pol; 2005;59(4):523-6
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  • Furthermore, macroscopically nonsuspected nasal polyp, usually benign tissue lesion, occasionally may be misdiagnosed such as neoplasm.
  • Only a few studies have undertaken the subject of cell proliferation in nonneoplastic respiratory epithelium.

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  • (PMID = 16273855.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
  • [Chemical-registry-number] 0 / Ki-67 Antigen
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2. Dunham CP, Curry B, Hamilton M: Malignant transformation of an intraaxial-supratentorial neurenteric cyst - case report and review of the literature. Clin Neuropathol; 2009 Nov-Dec;28(6):460-6
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  • Neurenteric cysts are "rare benign mass forming developmental abnormalities" that usually affect young adults.
  • Neurenteric cysts are thought to be derived from primitive endoderm, and form as a result of faulty endodermal-notochordal separation at 3 weeks of embryogenesis.
  • Neurenteric cysts are lined by simple-to-pseudostratified respiratory/gastrointestinal-like epithelium; as such, these lesions closely resemble colloid and Rathke's cleft cysts.
  • Areas of direct transition between typical benign neurenteric cyst epithelia and malignant epithelia (i.e., carcinoma in situ), highlighted by an abrupt change in the Ki-67 proliferative index, were identified, and supported the primary nature of this brain neoplasm.
  • [MeSH-major] Cystadenocarcinoma, Papillary / diagnosis. Cystadenocarcinoma, Papillary / etiology. Neural Tube Defects / complications. Supratentorial Neoplasms / diagnosis. Supratentorial Neoplasms / etiology

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  • (PMID = 19919821.001).
  • [ISSN] 0722-5091
  • [Journal-full-title] Clinical neuropathology
  • [ISO-abbreviation] Clin. Neuropathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 20
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3. Sente M: [External auditory canal osteoma]. Srp Arh Celok Lek; 2009 Jan-Feb;137(1-2):73-6
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  • INTRODUCTION: Osteomas are a slow growing benign neoplasm of unknown etiology very rarely involving the temporal bone.
  • Diagnosis is made based on case history, clinical examination, audiological processing and radiography (temporal bone CT scan), and confirmed by histopathological examination of the bone.
  • In terms of differential diagnosis, they must be distinguished from exostoses, bone tissue proliferation and osteoid osteomata.
  • The progress of the disease is prolonged, as they are slow growing, asymptomatic and benign tumours.
  • CASE OUTLINE: The report presents the case of a 70-year old patient with the osteoma of the right external auditory canal.
  • The clinical diagnosis was confirmed by CT scan of the temporal bone.
  • The method of choice in diagnosis is temporal bone CT scan.
  • [MeSH-major] Ear Canal. Ear Neoplasms / pathology. Osteoma / pathology. Skull Neoplasms / pathology. Temporal Bone

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  • (PMID = 19370970.001).
  • [ISSN] 0370-8179
  • [Journal-full-title] Srpski arhiv za celokupno lekarstvo
  • [ISO-abbreviation] Srp Arh Celok Lek
  • [Language] srp
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Serbia
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4. Gat Y, Gornish M, Heiblum M, Joshua S: Reversal of benign prostate hyperplasia by selective occlusion of impaired venous drainage in the male reproductive system: novel mechanism, new treatment. Andrologia; 2008 Oct;40(5):273-81
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  • [Title] Reversal of benign prostate hyperplasia by selective occlusion of impaired venous drainage in the male reproductive system: novel mechanism, new treatment.
  • Benign prostate hyperplasia (BPH) is the most common benign neoplasm in men.
  • We found that in all BPH patients, the one-way valves in the vertically oriented internal spermatic veins are destroyed (clinically manifested as varicocele), causing elevated hydrostatic pressure, some 6-fold greater than normal, in the venous drainage of the male reproductive system.
  • The elevated pressure propagates to all interconnected vessels leading to a unique biological phenomenon: venous blood flows retrograde from the higher pressure in the testicular venous drainage system to the low pressure in the prostatic drainage system directly to the prostate (law of communicating vessels).
  • We have treated 28 BPH patients using a technique that restores normal pressure in the venous drainage in the male reproductive system.
  • The back-pressure and the back-flow of blood from the testicular to the prostate drainage system were eliminated and, consequently, a rapid reduction in prostate volume and a regression of prostate symptoms took place.


5. Ozolek JA, Hunt JL: Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa. Am J Surg Pathol; 2006 Dec;30(12):1576-80
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  • [Title] Tumor suppressor gene alterations in respiratory epithelial adenomatoid hamartoma (REAH): comparison to sinonasal adenocarcinoma and inflamed sinonasal mucosa.
  • Respiratory epithelial adenomatoid hamartoma (REAH) is an unusual benign sinonasal glandular proliferation.
  • REAH is not considered a neoplasm, although, no molecular evidence exists to support or refute this possibility.
  • DNA was extracted and polymerase chain reaction performed using fluorescently labeled primers flanking known tumor suppressor genes on chromosomes 9p (CDKN2/p16), 11p (H-ras), 17p (p53), and 18q (DCC/DPC4).
  • The loss of heterozygosity (LOH) ratio was calculated as the allele ratio from tumor tissue divided by the allele ratio from normal tissue.
  • Appreciable allelic loss within REAH suggests the possibility that REAH may be a benign neoplasm rather than a hamartoma.
  • [MeSH-major] Adenocarcinoma / genetics. Genes, Tumor Suppressor. Hamartoma / genetics. Loss of Heterozygosity. Lung Diseases / genetics. Paranasal Sinus Neoplasms / genetics. Sinusitis / genetics
  • [MeSH-minor] Chromosomes, Human, 16-18. Chromosomes, Human, 6-12 and X. DNA / analysis. Humans. Microdissection. Paranasal Sinuses / pathology. Respiratory Mucosa / pathology


6. Wadasadawala T, Trivedi S, Gupta T, Epari S, Jalali R: The diagnostic dilemma of primary central nervous system melanoma. J Clin Neurosci; 2010 Aug;17(8):1014-1017
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  • [Title] The diagnostic dilemma of primary central nervous system melanoma.
  • Melanomas are malignant neoplasms of melanocytes developing predominantly in the skin, but occasionally arising from eyes, mucous membranes, and the central nervous system (CNS).
  • The CNS can be affected by a spectrum of melanocytic lesions ranging from diffuse neurocutaneous melanosis, to a focal and benign neoplasm (melanocytoma), and to an overtly malignant tumor (melanoma).
  • Primary CNS melanoma cannot be reliably distinguished from metastatic melanoma on neuroimaging and histopathological characteristics alone: its diagnosis is established only after exclusion of secondary metastatic disease from a cutaneous, mucosal or retinal primary.
  • [MeSH-major] Brain Neoplasms / pathology. Cerebellopontine Angle / pathology. Melanoma / pathology. Parietal Lobe / pathology

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  • (PMID = 20627582.001).
  • [ISSN] 1532-2653
  • [Journal-full-title] Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
  • [ISO-abbreviation] J Clin Neurosci
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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7. Tuzuner T, Kavak A, Parlak AH, Ustundag N: Subungual osteochondroma: a diagnostic dilemma. J Am Podiatr Med Assoc; 2006 Mar-Apr;96(2):154-7
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  • Osteochondroma is the most common skeletal neoplasm of all benign bone tumors.
  • [MeSH-major] Bone Neoplasms / diagnosis. Nail Diseases / diagnosis. Osteochondroma / diagnosis. Toe Phalanges / pathology

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  • (PMID = 16546954.001).
  • [ISSN] 8750-7315
  • [Journal-full-title] Journal of the American Podiatric Medical Association
  • [ISO-abbreviation] J Am Podiatr Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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8. Zachariou AG, Manoliadis IN, Kalogianni PA, Karagiannis GK, Georgantzis DJ: A rare case of bladder fibroepithelial polyp in childhood. Arch Ital Urol Androl; 2005 Jun;77(2):118-20
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  • OBJECTIVE: To present a rare case of a benign polyp in a child.
  • After a thorough laboratory investigation, which included urinalysis, urine culture, ultrasonography, intravenous pyelography and cystoscopy the presence of an exophytic papillary tumor in the bladder was identified.
  • RESULTS: The biopsy set the diagnosis of fibroepithelial polyp, which is a rare benign neoplasm and occurs in patients of nearly all ages.

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  • (PMID = 16146277.001).
  • [ISSN] 1124-3562
  • [Journal-full-title] Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica
  • [ISO-abbreviation] Arch Ital Urol Androl
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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9. Lee YC, Lee JW: Innovative treatment for huge nuchal desmoid tumour: a case report with a 2-year follow-up. J Plast Reconstr Aesthet Surg; 2010 Aug;63(8):e622-6
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  • BACKGROUND: The desmoid tumour is a monoclonal neoplasm originating from musculoaponeurotic tissues.
  • It is benign in histological presentations and yet its locally invasive behaviour could lead to dire consequences such as disfigurement, functional impairment or even mortality.
  • The patient went through a number of complications such as sepsis, acute respiratory distress and renal failure.
  • [MeSH-major] Embolization, Therapeutic / methods. Fibromatosis, Aggressive / therapy. Head and Neck Neoplasms / therapy. Suture Techniques / instrumentation. Tourniquets

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  • [Copyright] Copyright 2010 British Association of Plastic, Reconstructive and Aesthetic Surgeons. Published by Elsevier Ltd. All rights reserved.
  • (PMID = 20304713.001).
  • [ISSN] 1878-0539
  • [Journal-full-title] Journal of plastic, reconstructive & aesthetic surgery : JPRAS
  • [ISO-abbreviation] J Plast Reconstr Aesthet Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Netherlands
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10. Wang MZ, Li LY, Zhu ZH, Song ZF: [Application of positron emission tomography in diagnosis and staging for lung cancer]. Zhonghua Jie He He Hu Xi Za Zhi; 2005 Apr;28(4):221-4
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  • [Title] [Application of positron emission tomography in diagnosis and staging for lung cancer].
  • RESULTS: Of 104 patients, 64 (60%) had malignancy and 40 (40%) had a benign process.
  • The standard uptake ratio (SUV) in patients with lung cancer was significantly higher than that in patients with benign disease, 4.5 (1.2 - 11.7) and 1.0 (0 - 7.7) respectively.
  • [MeSH-major] Lung Neoplasms / pathology. Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods
  • [MeSH-minor] Aged. Female. Fluorodeoxyglucose F18. Humans. Male. Middle Aged. Neoplasm Staging. Sensitivity and Specificity

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  • (PMID = 15854428.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Evaluation Studies; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0Z5B2CJX4D / Fluorodeoxyglucose F18
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11. Lin C, Li J, Lu N: [Analysis of 2161 cases of neoplasm in oral maxillofacial region in Xinjiang]. Zhonghua Kou Qiang Yi Xue Za Zhi; 2010 Sep;45(9):553-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Analysis of 2161 cases of neoplasm in oral maxillofacial region in Xinjiang].
  • OBJECTIVE: To investigate the incidence and constituent characteristic of neoplasm in oromaxillo-facial region in Xinjiang.
  • METHODS: A total of 2161 patients with benign or malignant oral-maxillofacial tumors diagnosed in Department of Dentofacial Surgery of the First Affiliated Hospital of Xinjiang Medical College from 1995 to 2009 were analyzed retrospectively.
  • RESULTS: Of the 2161 cases, 58.49% (1264/2161) was benign tumors, 33.13% (716/2161) malignant tumors, and 8.38% (181/2161) tumor-like lesions.
  • The most common benign tumors were pleomorphic adenoma, hemangioma, papilloma, adenolymphoma and ameloblastoma.
  • CONCLUSIONS: The common pathological type of oral and maxillofacial benign neoplasm and the most common sites of malignancy in Xinjiang region were similar to those of other places inside and outside the country.
  • [MeSH-major] Mouth Neoplasms / pathology
  • [MeSH-minor] Adenolymphoma. Adenoma, Pleomorphic. Ameloblastoma. Carcinoma, Adenoid Cystic / epidemiology. Carcinoma, Adenoid Cystic / pathology. Carcinoma, Squamous Cell / epidemiology. Carcinoma, Squamous Cell / pathology. China / epidemiology. Face. Humans. Incidence. Mouth Mucosa. Odontogenic Tumors. Retrospective Studies. Salivary Gland Neoplasms

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  • (PMID = 21122451.001).
  • [ISSN] 1002-0098
  • [Journal-full-title] Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
  • [ISO-abbreviation] Zhonghua Kou Qiang Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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12. Wang W, Tavora F, Sharma R, Eisenberger M, Netto GJ: PSMA expression in Schwannoma: a potential clinical mimicker of metastatic prostate carcinoma. Urol Oncol; 2009 Sep-Oct;27(5):525-8
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  • PSMA expression has been shown in occasional nonprostatic neoplasms (e.g., urothelial adenocarcinoma) and in the vasculatures of other malignancies.
  • PSMA expression has not been described in benign neoplasms.
  • Recently, during evaluation of a prostatic carcinoma patient, we encountered a false positive PSMA radioimmunoscintigraphy scan in a pathologically confirmed Schwannoma (SCH) lesion.
  • PSMA expression was evaluated in tumor cells and lesional vessels.
  • RESULTS: All 11 SCH showed tumoral and or vascular staining; 7 (7/11) displayed both vascular and tumoral cell staining; the remaining 4 had only vascular staining (2/11) or tumor cell staining (2/11).
  • The extent of tumoral cell and vascular staining varied widely among lesions (tumor cells: focal in 8 and diffuse in 1; vascular: focal in 7, multifocal in 1, and diffuse in 1 lesion).
  • CONCLUSION: This is the first report of PSMA expression in a benign neoplasm.
  • Given our finding of frequent expression of PSMA in Schwannomas, they should be clinically considered in the differential diagnosis of a lesion that is positive on PSMA radioimmunoscintigraphy study performed during a metastatic work-up of PCa patient.
  • [MeSH-major] Antigens, Surface / biosynthesis. Biomarkers, Tumor / analysis. Glutamate Carboxypeptidase II / biosynthesis. Neurilemmoma / diagnosis
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Male. Middle Aged. Prostatic Neoplasms / diagnosis. Prostatic Neoplasms / metabolism. Prostatic Neoplasms / radionuclide imaging. Radionuclide Imaging

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  • (PMID = 18534872.001).
  • [ISSN] 1873-2496
  • [Journal-full-title] Urologic oncology
  • [ISO-abbreviation] Urol. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, Surface; 0 / Biomarkers, Tumor; EC 3.4.17.21 / Glutamate Carboxypeptidase II; EC 3.4.17.21 / glutamate carboxypeptidase II, human
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13. Li J, Wang ZQ, Zhang YM, Song HP, Yuan L: [Application of allogeneic bone in surgical treatment of benign bone neoplasm]. Nan Fang Yi Ke Da Xue Xue Bao; 2006 Jul;26(7):987-90
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  • [Title] [Application of allogeneic bone in surgical treatment of benign bone neoplasm].
  • OBJECTIVE: To evaluate the clinical outcomes of allogeneic bone grafting for bone defect resulting from benign neoplasm resection and discuss the clinical application and bone defect repair mechanisms of allogeneic bone.
  • METHODS: A retrospective review was conducted of 135 patients with benign neoplasm resection who received bone defect filling with the allogeneic bone graft.
  • CONCLUSION: Bone defect filling with allogeneic bone graft can be simple and safe in comparison with that with autograft or other biomaterials, and the bone healing time, infection rate and local tumor recurrence can be comparable with the autograft.
  • [MeSH-major] Bone Neoplasms / surgery. Bone Transplantation / methods

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  • (PMID = 16864094.001).
  • [ISSN] 1673-4254
  • [Journal-full-title] Nan fang yi ke da xue xue bao = Journal of Southern Medical University
  • [ISO-abbreviation] Nan Fang Yi Ke Da Xue Xue Bao
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
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14. Moreira PR, Guimarães MM, Guimarães AL, Diniz MG, Gomes CC, Brito JA, Gomez RS: Methylation of P16, P21, P27, RB1 and P53 genes in odontogenic keratocysts. J Oral Pathol Med; 2009 Jan;38(1):99-103
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  • BACKGROUND: Odontogenic keratocyst (OKC) is a benign neoplasm with an aggressive clinical behavior and a high recurrence rate.
  • [MeSH-major] DNA Methylation / genetics. Genes, Tumor Suppressor. Odontogenic Cysts / genetics

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  • (PMID = 19192054.001).
  • [ISSN] 1600-0714
  • [Journal-full-title] Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
  • [ISO-abbreviation] J. Oral Pathol. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / CDKN1A protein, human; 0 / Cyclin-Dependent Kinase Inhibitor p21; 0 / Retinoblastoma Protein; 147604-94-2 / Cyclin-Dependent Kinase Inhibitor p27
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15. Bisdas S, Baghi M, Huebner F, Mueller C, Knecht R, Vorbuchner M, Ruff J, Gstoettner W, Vogl TJ: In vivo proton MR spectroscopy of primary tumours, nodal and recurrent disease of the extracranial head and neck. Eur Radiol; 2007 Jan;17(1):251-7
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  • Benign and malignant neoplasms as well as metastatic lymph nodes of 39 patients were examined using localized single voxel magnetic resonance spectroscopy (MRS) [repetition time (TR) 1500, echo time (TE) 135) at 1.5 T.
  • New techniques with simultaneous correction of motion artefacts during the acquisition, three-dimensional saturation pulses, respiratory triggering and smaller volume of interest (VOI) size, were applied.
  • The Cho/Cr ratios in all malignant neoplasms (mean: 5.2, range: 1.7-17.8) were significantly elevated relative to those in the normal muscle structures (mean: 0.9, range: 0.2-1.4), while those in the benign neoplasms were elevated (mean: 24.4, range: 1.4-59.7) with respect to those in the malignant ones.
  • The average Cho/Cr ratio in the metastatic lymph nodes was significantly higher (mean: 4.8, range: 3.3-5.6) than that for benign lymphoid hyperplasia (mean: 2.2, range: 1.0-3.0).
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Magnetic Resonance Spectroscopy. Neoplasm Recurrence, Local / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Feasibility Studies. Female. Humans. Lymphatic Metastasis / diagnosis. Male. Middle Aged

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  • (PMID = 16703309.001).
  • [ISSN] 0938-7994
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
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16. Shah SN: Giant myofibroblastoma of breast: a case report. Indian J Pathol Microbiol; 2007 Jul;50(3):583-5
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  • Myofibroblastoma of the breast is a very rare benign neoplasm usually seen in elderly male and is of very small size.
  • The case was clinically diagnosed as Phyllodes tumor Left mastectomy was done.
  • The tumor was histopathologically and immunohistochemically diagnosed as Myofibroblastoma.
  • [MeSH-major] Breast Neoplasms / diagnosis. Neoplasms, Muscle Tissue / diagnosis

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  • (PMID = 17883145.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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17. Angiero F: Ectomesenchymal chondromyxoid tumour of the tongue. A review of histological and immunohistochemical features. Anticancer Res; 2010 Nov;30(11):4685-9
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  • BACKGROUND: Ectomesenchymal chondromyxoid tumour (ECT) is a rare, benign neoplasm of uncertain histogenesis, which appears to exclusively involve the oral cavity, particularly the tongue.
  • CASE REPORT: We report the case of a 27-year-old woman with a 0.7 cm tumoral lesion of 3 months' duration on the dorsum of the tongue.
  • The diagnosis was consistent with ECT.
  • Immunohistochemical expression of S100, glial fibrillary acidic protein and vimentin, very helpful in confirming diagnosis, suggest a probable mesenchymal and neural origin of this rare entity.
  • [MeSH-major] Chondroma / pathology. Mesenchymoma / pathology. Myxoma / pathology. Tongue Neoplasms / pathology
  • [MeSH-minor] Adult. Desmin / metabolism. Diagnosis, Differential. Female. Glial Fibrillary Acidic Protein / metabolism. Humans. Immunoenzyme Techniques. S100 Proteins / metabolism. Vimentin / metabolism

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  • (PMID = 21115924.001).
  • [ISSN] 1791-7530
  • [Journal-full-title] Anticancer research
  • [ISO-abbreviation] Anticancer Res.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / Desmin; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins; 0 / Vimentin
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18. Adhikari RC, Tuladhar A, Shrestha S, Sharma SK: Deep-seated thoracic and abdominal lesions: usefulness of ultrasound guided fine needle aspiration cytology, a 3 year experience. Nepal Med Coll J; 2010 Mar;12(1):20-5
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  • The aim of this study was to evaluate the overall utility of ultrasonographic guided FNAC in the diagnosis of abdominal and thoracic lesions.
  • In 264 cases (82.5%), FNAC was diagnostic with commonest diagnosis being malignant neoplasm (70.0%).
  • In liver, Metastatic adenocarcinoma is the commonest tumor, while in lung; the commonest lesion is non-small cell carcinoma.
  • Benign neoplasm (3.1%) and non neoplastic lesion (9.4%) were also diagnosed by FNAC.
  • [MeSH-major] Neoplasms / diagnosis. Ultrasonography, Interventional

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  • (PMID = 20677604.001).
  • [Journal-full-title] Nepal Medical College journal : NMCJ
  • [ISO-abbreviation] Nepal Med Coll J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Nepal
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19. Siriwardana PN, Pathirana A: Episodic biliary obstruction due to an intrahepatic biliary cystadenoma: a case report. J Med Case Rep; 2009;3:9032
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  • INTRODUCTION: Biliary cystadenoma is a rare, benign neoplasm of the bile ducts with malignant potential.
  • Symptoms, predominantly right hypochondrial pain and the feeling of a lump or fullness are usually due to the mass effect.
  • CONCLUSION: Biliary cystadenoma should be considered as a differential diagnosis in patients with cystic liver lesions who present with episodic biliary obstruction.

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  • (PMID = 19918286.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2767148
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20. Giri D: Recurrent challenges in the evaluation of fibroepithelial lesions. Arch Pathol Lab Med; 2009 May;133(5):713-21
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  • CONTEXT: The morphologic spectrum of mammary fibroepithelial lesions ranges from fibroadenoma, a common benign neoplasm, to phyllodes tumor, an uncommon lesion that can sometimes recur and metastasize.
  • OBJECTIVE: To focus on problems encountered in the diagnostic evaluation of fibroepithelial tumors, highlighting the diagnostically relevant morphologic features and providing an update on the immunohistochemical profile and genetic alterations of these rare neoplasms.
  • DATA SOURCES: A PubMed search of the English-language literature identified published reports on fibroepithelial lesions, with a special focus on phyllodes tumor.
  • CONCLUSIONS: The distinction between fibroadenoma and phyllodes tumor is usually not problematic, especially in excision specimens.
  • Morphologic predictors of local recurrence of phyllodes tumor include cellularity and cytologic atypia, mitotic activity, positive margins, infiltrative borders, fibroproliferative satellite nodules, and past history of fibroadenoma.
  • Predictors of distant metastasis include size, tumor necrosis, and stromal overgrowth.
  • Presently, molecular and immunohistochemical techniques play a limited role in the diagnosis of fibroepithelial lesions.
  • [MeSH-major] Breast Neoplasms / diagnosis. Fibroadenoma / diagnosis. Phyllodes Tumor / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / analysis. DNA, Neoplasm / analysis. Diagnosis, Differential. Female. Gene Expression. Humans. Immunoenzyme Techniques. Neoplasm Recurrence, Local

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  • (PMID = 19415945.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
  • [Number-of-references] 46
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21. Yang Y, Nie X, Lu J, Lu XY, Wei YY, Wang H, Han ZH, Chen ZH, Zheng J: [Mixed epithelial and stromal tumor of kidney]. Zhonghua Bing Li Xue Za Zhi; 2006 Jan;35(1):29-31
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  • [Title] [Mixed epithelial and stromal tumor of kidney].
  • OBJECTIVE: To study the clinicopathological features and differential diagnoses of mixed epithelial and stromal tumor of the kidney.
  • METHODS: Clinical and pathological characteristics of 4 cases of mixed epithelial and stromal tumor of the kidney were studied.
  • Microscopically, the tumors were composed of a mixture of stromal and epithelial elements.
  • Stromal elements essentially consisted of spindle cells, with thick-walled blood vessels and bands of smooth muscle cells as distinctive features of the tumor.
  • CONCLUSIONS: Mixed epithelial and stromal tumor of the kidney is a benign neoplasm with distinct histopathological features.
  • It should be distinguished from many other renal neoplasms.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Muscle, Smooth / metabolism. Nephrectomy / methods. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16608646.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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22. Subhashraj K, Balanand S, Pajaniammalle S: Ancient schwannoma arising from mental nerve. A case report and review. Med Oral Patol Oral Cir Bucal; 2009 Jan;14(1):E12-4
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  • Schwannoma is an intraoral rare, benign neoplasm derived from the nerve sheath of peripheral nerves.
  • "Ancient schwannoma" shows histopathological features, such as degenerative changes and atypical nuclei, and may easily be confused with malignant neoplasms.
  • Ultrasonography showed that the tumor was closely associated with the mental nerve on the left side, suggestive of a peripheral neural sheath tumor.
  • [MeSH-major] Chin / innervation. Neurilemmoma / pathology. Peripheral Nervous System Neoplasms / pathology

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  • (PMID = 19114949.001).
  • [ISSN] 1698-6946
  • [Journal-full-title] Medicina oral, patología oral y cirugía bucal
  • [ISO-abbreviation] Med Oral Patol Oral Cir Bucal
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 11
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23. Czecior E, Namysłowski G, Misiołek M, Scierski W, Polok A, Lisowska G, Mrówka-Kata K, Orecka B, Pawlas P: [Strategy of the sinonasal tumors treatment]. Otolaryngol Pol; 2007;61(4):559-61
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  • They state 0.2-0.8% of all the malignant neoplasms and about 3% of head and neck tumors.
  • RESULTS: In the histological examination in 4 patients the benign neoplasm and in 22 patients malignant tumors were diagnosed.
  • On the basis of the CT and MRI examination as well as the description of the surgical procedure we stated that in 13 cases the primary localization of neoplasm was the maxillary sinus, in 5 cases ethmoidal cells, in 3 nasal cavity.
  • In one patient the estimation of primary tumor localization was not possible, because of the very large extension of the neoplasm.
  • The choice of the surgical procedure was depend on the tumor extension and localization.
  • [MeSH-major] Nose Neoplasms / diagnosis. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / diagnosis. Paranasal Sinus Neoplasms / surgery

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  • (PMID = 18260251.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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24. Holland KE, Galbraith SS: Generalized congenital smooth muscle hamartoma presenting with hypertrichosis, excess skin folds, and follicular dimpling. Pediatr Dermatol; 2008 Mar-Apr;25(2):236-9
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  • While smooth muscle hamartoma classically presents as a small hairy, skin-colored to hyperpigmented patch or plaque, rare presentations with diffuse involvement or follicular papules have been described.
  • We present our patient and review the literature to highlight the diverse and under recognized manifestations of this benign neoplasm.
  • [MeSH-major] Hamartoma / congenital. Hamartoma / diagnosis. Muscle, Smooth / pathology. Skin Neoplasms / congenital. Skin Neoplasms / diagnosis

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  • (PMID = 18429788.001).
  • [ISSN] 1525-1470
  • [Journal-full-title] Pediatric dermatology
  • [ISO-abbreviation] Pediatr Dermatol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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25. Scheuermann K, Delank KW: [Ackerman's tumor of the larynx and occupational exposure to asbestos]. Laryngorhinootologie; 2007 Aug;86(8):588-91
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  • [Title] [Ackerman's tumor of the larynx and occupational exposure to asbestos].
  • [Transliterated title] Ackerman-Tumor des Larynx und berufliche Asbestexposition.
  • The so-called "Ackerman's tumor" is a neoplasm of uncertain dignity.
  • Aim of this paper is to clarify, whether this is an asbestos-induced tumor of the larynx in accordance with German regulations for occupational diseases.
  • A 43-year old male presented the clinical picture of a stenosing laryngeal tumor.
  • A verrucous neoplasm without a proven malignity in the sense of an Ackerman's tumor was diagnosed through several sequential biopsies.
  • Approximately 2 years later a total laryngectomy was performed, because of a squamous cell carcinoma of the larynx.
  • An Ackerman's tumor is--in accordance with its definition in the German-speaking area--not conclusively malignant, there is no indication of a relation between asbestos and such a tumor in literature, there is no specific benign disorder of the larynx caused by asbestos.
  • This brings us to the conclusion that the Ackerman's tumor of the larynx is no asbestos-induced laryngeal tumor as per German occupational disease regulations.
  • [MeSH-major] Asbestosis / diagnosis. Carcinoma, Verrucous / diagnosis. Laryngeal Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis
  • [MeSH-minor] Adult. Aphonia / etiology. Biopsy. Cell Transformation, Neoplastic / pathology. Diagnosis, Differential. Disease Progression. Hoarseness / etiology. Humans. Laryngoscopy. Larynx / pathology. Lymph Node Excision. Male. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Neoplasm Staging. Reoperation. Respiratory Sounds / etiology

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  • (PMID = 17806001.001).
  • [ISSN] 0935-8943
  • [Journal-full-title] Laryngo- rhino- otologie
  • [ISO-abbreviation] Laryngorhinootologie
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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26. Abu-Amero KK, Alzahrani AS, Zou M, Shi Y: High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines. Oncogene; 2005 Feb 17;24(8):1455-60
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  • [Title] High frequency of somatic mitochondrial DNA mutations in human thyroid carcinomas and complex I respiratory defect in thyroid cancer cell lines.
  • Significant progress has been made to elucidate the molecular mechanisms that determine thyroid tumor development and progression.
  • In the present study, we investigated the frequency of mtDNA mutations in 24 thyroid tumor specimens (19 primary papillary thyroid carcinomas (PTC), one follicular thyroid carcinoma, and four multinodular hyperplasias) and four thyroid cancer cell lines by sequencing the entire coding regions of mitochondrial genome.
  • All the thyroid tumor cell lines carried sequence variations that change amino acid and have not been reported previously as normal sequence variants.
  • Flow cytometry analysis of mitochondria respiratory function in the thyroid tumor cell lines revealed a severe defect in mitochondrial complex I activity.
  • The mutations were either A --> G or C --> T transitions, often resulting in a change of a moderately or highly conserved amino acid of their corresponding protein.
  • Given that mtDNA mutation is present in the benign multinodular hyperplasia, it might be involved in the early stage of tumor development.
  • [MeSH-major] Carcinoma / genetics. DNA, Mitochondrial / genetics. Electron Transport Complex I / physiology. Mutation / genetics. Thyroid Neoplasms / genetics
  • [MeSH-minor] Cell Line, Tumor. Humans. Neoplasm Staging

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  • (PMID = 15608681.001).
  • [ISSN] 0950-9232
  • [Journal-full-title] Oncogene
  • [ISO-abbreviation] Oncogene
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; EC 1.6.5.3 / Electron Transport Complex I
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27. Rydzewski B, Goździcka-Józefiak A, Sokalski J, Matusiak M, Durzyński L: [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms]. Otolaryngol Pol; 2007;61(2):137-41
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  • [Title] [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms].
  • INTRODUCTION: Human Papilloma Virus has a strong relation to oropharyngeal mucosa and is considered to be responsible for a wide range of upper respiratory tract pathologies, like laryngeal papilloma.
  • There's a hypothesis, that it plays a significant role in middle ear chronic inflammations and neoplasm's.
  • The examination was carried on a group of 53 patients, 39 of which was suffering from granulation tissue chronic otitis media, 7-cholesteatomatous otitis media, 6--middle ear malignant neoplasm, and 1 middle and/or external ear benign neoplasm.
  • The material was postoperative tissue, like polyps, inflammatory granulation tissue, cholesteatoma masses and malignant neoplasm's tissue.
  • In every case of middle ear malignant neoplasm a presence of high-risk DNA Papilloma types 16 or 18 was confirmed.
  • CONCLUSIONS: The results has been compared with other authors examinations and it is claimed that they confirm the observation, that Human Papilloma Viruses may be a factor, that might play an important role in pathology of chronic otitis media and ear neoplasm's.
  • It is concluded, that differences in percentages of HPV presence in chronic inflammations (70%) and ear neoplasm's may be explained by viral co-infection during bacterial c. o. m.
  • [MeSH-major] Ear / virology. Ear Neoplasms / virology. Papilloma / genetics. Papilloma / virology. Papillomavirus Infections / diagnosis. Tumor Virus Infections / diagnosis. Tumor Virus Infections / virology

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  • (PMID = 17668798.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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28. Abdalla RJ, Cohen M, Nóbrega J, Forgas A: SYNOVIAL GIANT CELL TUMOR OF THE KNEE. Rev Bras Ortop; 2009 Jan;44(5):437-40
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  • [Title] SYNOVIAL GIANT CELL TUMOR OF THE KNEE.
  • Synovial giant cell tumor is a benign neoplasm, rarely reported in the form of malignant metastasis.
  • Synovial giant cell tumor most frequently occurs on the hand, and, most uncommon, on the ankle and knee.
  • In the present study, the authors describe a rare case of synovial giant cell tumor on the knee as well as the treatment approach.
  • Arthroscopy has been shown, in this case, to be the optimal method for treating this kind of lesion, once it allowed a less aggressive approach, while providing good visualization of all compartments of knee joint and full tumor resection.

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  • (PMID = 27004193.001).
  • [ISSN] 2255-4971
  • [Journal-full-title] Revista brasileira de ortopedia
  • [ISO-abbreviation] Rev Bras Ortop
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC4783680
  • [Keywords] NOTNLM ; Giant cell tumor / Knee / Neoplasm / Synovial
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29. Josephson GD, Patel SA, Duckworth L, Kress M, Goldstein J: Neurilemmoma presenting as a midline nasal mass in a pediatric patient. Ear Nose Throat J; 2010 May;89(5):221-3
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  • [Title] Neurilemmoma presenting as a midline nasal mass in a pediatric patient.
  • We report a case of a neurilemmoma presenting as a midline nasal mass in a 13-year-old girl.
  • To the best of our knowledge, this is the first report of a nasal neurilemmoma in a pediatric patient.
  • Although this neoplasm is benign in nature, surgical resection is warranted to prevent recurrence, and it is the sole means of treatment.
  • We discuss the diagnosis and management of neurilemmomas and urge physicians not to exclude nasal neurilemmoma from the differential diagnosis in a pediatric patient who presents with a nasal mass.
  • [MeSH-major] Nasal Cavity / pathology. Neurilemmoma / pathology. Nose Neoplasms / pathology
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Female. Humans

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  • (PMID = 20461682.001).
  • [ISSN] 1942-7522
  • [Journal-full-title] Ear, nose, & throat journal
  • [ISO-abbreviation] Ear Nose Throat J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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30. Józefowicz-Korczyńska M, Kozłowski Z, Pietruszewska W, Lukomski M: [Granular-cell myoblastoma of the larynx clinical analysis]. Otolaryngol Pol; 2005;59(6):807-12
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  • Granular-cell tumor is a rare, usually benign neoplasm that can occur in various part of the body.
  • The larynx tumor is accounting for 7% to 10% of all reported cases.
  • The tumor was generally presented in patients in their forth and fifth decade.
  • Clinically the tumors were considered benign.
  • In one case because the location and size of the tumor subtotal laryngectomy was necessary to conduct.
  • [MeSH-major] Granular Cell Tumor / pathology. Laryngeal Neoplasms / pathology

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  • (PMID = 16521442.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Poland
  • [Number-of-references] 18
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31. Ceylan A, Celenk F, Poyraz A, Uslu S: Pleomorphic adenoma of the nasal columella. Pathol Res Pract; 2008;204(4):273-6
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  • Pleomorphic adenoma (mixed tumor) is the most common benign neoplasm of the salivary glands.
  • [MeSH-major] Adenoma, Pleomorphic / pathology. Neoplasm Recurrence, Local. Neoplasm Seeding. Nose Neoplasms / pathology

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  • (PMID = 18295980.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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32. Vansteenkiste JF, Stroobants SS: PET scan in lung cancer: current recommendations and innovation. J Thorac Oncol; 2006 Jan;1(1):71-3
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  • FDG-PET is recommended for the diagnosis of indeterminate pulmonary nodules, for which it is significantly more accurate than computed tomography (CT) in the distinction between benign and malignant lesions.
  • [MeSH-major] Lung Neoplasms / radionuclide imaging. Positron-Emission Tomography / methods. Practice Guidelines as Topic
  • [MeSH-minor] Diagnosis, Differential. Fluorodeoxyglucose F18. Humans. Neoplasm Staging / methods. Radiopharmaceuticals. Reproducibility of Results

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  • (PMID = 17409830.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 19
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33. Burke A, Li L, Kling E, Kutys R, Virmani R, Miettinen M: Cardiac inflammatory myofibroblastic tumor: a "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death. Am J Surg Pathol; 2007 Jul;31(7):1115-22
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  • [Title] Cardiac inflammatory myofibroblastic tumor: a "benign" neoplasm that may result in syncope, myocardial infarction, and sudden death.
  • All tumors were surgical resections, except 1 tumor that resulted in sudden coronary death and that was diagnosed at autopsy, and 1 tumor that embolized into the coronary artery and was treated by cardiac transplant.
  • Although there were frequent collagen bundles interspersed among the tumor cells, there were no large areas of dense fibrosis.


34. Starost MF: Adenomyofibroma of the fimbria in a cynomolgus monkey (Macaca fascicularis). J Vet Diagn Invest; 2009 Nov;21(6):892-4
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  • A diagnosis of adenomyofibroma of the fimbria was made.
  • This benign neoplasm should be considered as a differential diagnosis for masses arising from the fallopian tube in old-world macaques.
  • [MeSH-minor] Animals. Animals, Laboratory. Diagnosis, Differential. Dog Diseases / pathology. Dogs. Female. Genitalia, Female / pathology. Macaca fascicularis

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  • (PMID = 19901298.001).
  • [ISSN] 1040-6387
  • [Journal-full-title] Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc
  • [ISO-abbreviation] J. Vet. Diagn. Invest.
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Case Reports; Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
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35. Singh J, James SL, Kroon HM, Woertler K, Anderson SE, Jundt G, Davies AM: Tumour and tumour-like lesions of the patella--a multicentre experience. Eur Radiol; 2009 Mar;19(3):701-12
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  • Of the 59 cases, 46% were non neoplastic, 39% were benign and 15% were malignant.
  • The commonest benign neoplasm was giant cell tumour (GCT) (11 cases).
  • Younger patients were more likely to have a benign neoplasm.
  • [MeSH-major] Bone Neoplasms / pathology. Giant Cell Tumors / pathology. Patella / pathology
  • [MeSH-minor] Adolescent. Adult. Age Factors. Diagnosis, Differential. Female. Humans. Male. Medical Oncology / methods. Middle Aged. Neoplasm Metastasis. Radiology / methods

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  • [ErratumIn] Eur Radiol. 2010 Mar;20(3):763. Jundt, G [added]
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  • (PMID = 18815789.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
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36. Abeysekara AM, Siriwardana HP, Abbas KF, Tanner P, Ojo AA: An unusually large myofibroblastoma in a male breast: a case report. J Med Case Rep; 2008;2:157
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  • INTRODUCTION: Myofibroblastoma of the breast is a rare benign stromal tumour seen predominantly in men.
  • The gross appearance is that of a well-circumscribed nodule, characteristically small, seldom exceeding 3 cm.
  • Myofibroblastomas can mimic malignant neoplasms and the clinical significance of this entity lies primarily in its recognition as a distinctive benign neoplasm.

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  • (PMID = 18479528.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2396649
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37. Birman MV, McHugh JB, Hayden RJ, Jebson PJ: Pilomatrixoma of the forearm: a case report. Iowa Orthop J; 2009;29:121-3
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  • Pilomatrixoma is a benign neoplasm derived from hair follicle matrix cells.
  • We present the case of a 52-year-old woman with a pilomatrixoma of the forearm, and we review the literature regarding pilomatrixomas in the upper extremity.
  • [MeSH-major] Pilomatrixoma / diagnosis. Skin Neoplasms / diagnosis

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  • (PMID = 19742099.001).
  • [ISSN] 1555-1377
  • [Journal-full-title] The Iowa orthopaedic journal
  • [ISO-abbreviation] Iowa Orthop J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 17
  • [Other-IDs] NLM/ PMC2723706
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38. Whitten KA, Popielarczyk MM, Belote DA, McLeod GC, Mense MG: Ossifying fibroma in a miniature rex rabbit (Oryctolagus cuniculus). Vet Pathol; 2006 Jan;43(1):62-4
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  • In humans and animals, ossifying fibroma is a benign neoplasm that most frequently affects the mandible, often resulting in cosmetic deformities and malocclusion.
  • A surgical biopsy of a solitary mass located beneath the gingiva in the right maxillary region, which had overgrown teeth and expanded the adjacent hard palate from a 6-year-old miniature Rex rabbit was submitted for light microscopic examination.
  • Histopathologically, the neoplasm was composed of fibroblastic cells separated by abundant collagen.
  • Based on the histopathologic features, the tumor was diagnosed as an ossifying fibroma.
  • [MeSH-major] Bone Neoplasms / veterinary. Fibroma, Ossifying / veterinary. Maxilla / pathology. Rabbits
  • [MeSH-minor] Animals. Diagnosis, Differential

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  • (PMID = 16407489.001).
  • [ISSN] 0300-9858
  • [Journal-full-title] Veterinary pathology
  • [ISO-abbreviation] Vet. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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39. Kerkeni A, Ben Lakhdher Z, Rkhami M, Sebai R, Belguith L, Khaldi M, Ben Hamouda M: [Central neurocytoma: Study of 32 cases and review of the literature]. Neurochirurgie; 2010 Oct;56(5):408-14
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  • [Transliterated title] Le neurocytome central : étude de 32 cas et revue de la littérature.
  • Central neurocytoma is a rare benign neoplasm of the central nervous system.
  • The intraventricular location close to the Monro foramina and the attachment to the septum pellucidum are characteristic for the diagnosis.
  • However, atypical appearances may be encountered and confused with other neoplasms.
  • [MeSH-major] Brain Neoplasms. Neurocytoma

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  • [Copyright] Copyright © 2010 Elsevier Masson SAS. All rights reserved.
  • (PMID = 20692674.001).
  • [ISSN] 1773-0619
  • [Journal-full-title] Neuro-Chirurgie
  • [ISO-abbreviation] Neurochirurgie
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
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40. Chella B, Nosotti M, Baisi A, Lattuada E, Mazzone A, Santambrogio L: Unusual presentation of a transparietal cavernous hemangioma of the esophagus. Dis Esophagus; 2005;18(5):349-54
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  • [Title] Unusual presentation of a transparietal cavernous hemangioma of the esophagus.
  • Hemangiomas are tumors of vascular origin and represent less than 3% of benign neoplasm of the esophagus.
  • We herein report a case of a 55-year-old man, who presented transitory dysphagia and weight loss.
  • Only after partial esophagectomy with laparoscopic gastric mobilization was histological diagnosis obtained.
  • In fact, on microscopic observation of the specimen, the neoplasm appeared to be a cavernous hemangioma of the esophageal submucosa with transparietal extension.

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  • (PMID = 16197539.001).
  • [ISSN] 1120-8694
  • [Journal-full-title] Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus
  • [ISO-abbreviation] Dis. Esophagus
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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41. Kim SY, Jeon TJ, Hong JH, Kim GS, Oh TH, Seo DD, Shin WC, Choi WC: [An adult case of small bowel intussusception caused by hemangioma presenting with intestinal bleeding]. Korean J Gastroenterol; 2008 Sep;52(3):183-7
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  • Unlike childhood intussusception, adult intussusception has an identifiable leading lesion such as malignant or benign neoplasm.
  • Therefore, small bowel intussusception by hemangioma should be also considered as a bleeding focus when an adult patient presented intestinal bleeding without bleeding focus in the stomach and colon.
  • [MeSH-major] Gastrointestinal Hemorrhage / etiology. Hemangioma / complications. Intestinal Neoplasms / complications. Intestine, Small. Intussusception / diagnosis
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Tomography, X-Ray Computed

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  • (PMID = 19077515.001).
  • [ISSN] 1598-9992
  • [Journal-full-title] The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
  • [ISO-abbreviation] Korean J Gastroenterol
  • [Language] kor
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Korea (South)
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42. Wang MZ, Wan XB, Chen Y, Zhang L, Zhong W, Zhong X, Shi JH, Liu T, Huang H, Zhang H, Xiao Y, Cai BQ, Li LY: [The results of transbronchial needle aspiration in 164 cases with enlarged mediastinal and/or hilar lymph nodes]. Zhonghua Nei Ke Za Zhi; 2009 Feb;48(2):133-5
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  • OBJECTIVE: To evaluate the role of transbronchial needle aspiration (TBNA) in the diagnosis of patients with enlarged mediastinal and/or hilar lymph node.
  • RESULTS: From June 1 2004 to December 31 2007, 164 patients were examined: including 80 lung cancers, 69 lung benign diseases, 2 other malignancy tumor, and 13 without definite diagnosis.
  • There were 25 patients that diagnosis of lung cancer was pathologically determined by TBNA only.
  • From June 1 2006 to December 31 2007, lymph node tissues able to make histology diagnosis were yield in 73.5% (64/87) patients.
  • CONCLUSION: TBNA is quite safe and helpful in diagnosis and staging of bronchogenic carcinoma, and in diagnosis of benign lung diseases.
  • [MeSH-major] Biopsy, Needle / methods. Lung Neoplasms / pathology. Lymph Nodes / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Mediastinum / pathology. Middle Aged. Neoplasm Staging. Young Adult

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  • (PMID = 19549469.001).
  • [ISSN] 0578-1426
  • [Journal-full-title] Zhonghua nei ke za zhi
  • [ISO-abbreviation] Zhonghua Nei Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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43. de Lacerda SA, Brentegani LG, Rosa AL, Vespúcio MV, Salata LA: Intraosseous schwannoma of mandibular symphysis: case report. Braz Dent J; 2006;17(3):255-8
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  • Schwannoma (neurilemmoma) is a benign neoplasm originated from the neural sheath and occurring most frequently in the head and neck.
  • [MeSH-major] Mandibular Neoplasms / diagnosis. Neurilemmoma / diagnosis

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  • (PMID = 17262135.001).
  • [ISSN] 0103-6440
  • [Journal-full-title] Brazilian dental journal
  • [ISO-abbreviation] Braz Dent J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Brazil
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44. Kloboves-Prevodnik VV, Us-Krasovec M, Gale N, Lamovec J: Cytological features of lipoblastoma: a report of three cases. Diagn Cytopathol; 2005 Sep;33(3):195-200
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  • Lipoblastoma is a rare benign neoplasm occurring mostly in children under the age of three.
  • Accurate preoperative diagnosis is mandatory for planning the treatment.
  • The main aim of this study is to establish the cytological features of lipoblastoma and to answer the question: "Is cytological diagnosis of lipoblastoma reliable?
  • The tumor cells were in clusters and tissue fragments or as single cells.
  • In the first case, the cytological diagnosis was benign soft-tissue tumor, in the second the diagnosis was not conclusive and the last case was correctly diagnosed as lipoblastoma.
  • In the differential diagnosis of the second case, both lipoblastoma and liposarcoma were considered cytologically as well as histologically.
  • [MeSH-major] Lipoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Biopsy, Fine-Needle. Diagnosis, Differential. Female. Humans. Infant. Male

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  • [Copyright] Copyright (c) 2005 Wiley-Liss, Inc.
  • (PMID = 16078242.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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45. Tatli S, Lipton MJ: CT for intracardiac thrombi and tumors. Int J Cardiovasc Imaging; 2005 Feb;21(1):115-31
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  • Although cardiac tumors are rare, they nevertheless represent an important subgroup, the diagnosis of which is challenging for the primary care physician.
  • Symptoms are not characteristic and serious complications including stroke, myocardial infarction and even sudden death from arrhythmia may be the first signs of tumor.
  • The most common primary cardiac neoplasm is the benign myxoma and the most frequent primary malignant lesion is sarcoma.
  • Echocardiography and angiocardiography with or without coronary arteriography remain routine methods for evaluating cardiac neoplasms.
  • This chapter reviews the wide spectrum of intracardiac thrombi and tumors including their incidence and imaging characteristics with particular reference to the CT findings and differential diagnosis.
  • [MeSH-major] Coronary Thrombosis / diagnostic imaging. Heart Neoplasms / diagnostic imaging. Myxoma / diagnostic imaging. Sarcoma / diagnostic imaging. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 15915945.001).
  • [ISSN] 1569-5794
  • [Journal-full-title] The international journal of cardiovascular imaging
  • [ISO-abbreviation] Int J Cardiovasc Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 76
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46. Ponce-Camacho MA, Diaz de Leon-Medina R, Miranda-Maldonado I, Garza-Guajardo R, Hernandez-Salazar J, Barboza-Quintana O: A 5-year-old girl with a congenital ganglioneuroma diagnosed by fine needle aspiration biopsy: a case report. Cytojournal; 2008;5:5
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  • INTRODUCTION: Ganglioneuroma is a rare, benign, neuroblastic tumor arising mainly from the central or peripheral autonomic nervous system, especially the sympathetic system.
  • A diagnosis of ganglioneuroma was suggested.
  • Core biopsy and surgical resection confirmed this diagnosis.
  • CONCLUSION: Congenital ganglioneuroma of the cervical region is an uncommon soft tissue benign neoplasm of neuroblastic origin, and it should be considered in the differential diagnosis of head and neck pediatric soft tissue tumors.

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  • (PMID = 18373875.001).
  • [ISSN] 1742-6413
  • [Journal-full-title] CytoJournal
  • [ISO-abbreviation] Cytojournal
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2359765
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47. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • [Title] Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases.
  • BACKGROUND: The diagnosis of retroperitoneal lesions is one of the most difficult areas in surgical pathology.
  • Fine needle aspiration cytology has shown promising role in establishing the diagnosis in this region.
  • OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.
  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).
  • CONCLUSIONS: USG-guided FNAC is an inexpensive, rapid, safe, and accurate procedure for the diagnosis of retroperitoneal masses.

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  • (PMID = 21938165.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168018
  • [Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum
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48. Jin MS, Ha HJ, Baek HJ, Lee JC, Koh JS: Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report. Acta Cytol; 2008 May-Jun;52(3):357-60
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  • [Title] Adenomyomatous hamartoma of lung mimicking benign mucinous tumor in fine needle aspiration biopsy: a case report.
  • BACKGROUND: Typical cytologic features of pulmonary hamartoma (PH) are usually smears of hyaline cartilage, fibrous tissue, smooth muscle, adipocytic components and respiratory epithelium.
  • Cytologic features of adenomyomatous hamartoma, a special variant of PH, are not documented in the literature and are confused with epithelial neoplasm in the case of sparse stromal cellularity.
  • Fine needle aspiration biopsy (FNAB) revealed numerous mucinous epithelial cells presenting predominantly in cohesive cellular sheets that suggested benign mucinous epithelial lesion.
  • The patient underwent surgery for the tumor, and it was histologically proven to be an adenomyomatous hamartoma.
  • This case demonstrates the wide spectrum of PH in FNAB and led us to consider PH as a differential diagnosis despite lack of chondromyxoid stromal components.
  • [MeSH-major] Biopsy, Fine-Needle. Hamartoma / diagnosis. Lung Neoplasms / diagnosis
  • [MeSH-minor] Carcinoma, Mucoepidermoid / diagnosis. Carcinoma, Mucoepidermoid / pathology. Diagnosis, Differential. Humans. Male. Middle Aged. Thoracic Surgery, Video-Assisted. Treatment Outcome

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  • (PMID = 18540306.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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49. Lanza A, Moscariello A, Villani R, Colella G: Glomus tumor of the lower lip. A case report. Minerva Stomatol; 2005 Nov-Dec;54(11-12):687-90
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  • [Title] Glomus tumor of the lower lip. A case report.
  • A glomus tumor is a benign neoplasm originating from the modified smooth muscle cells of the vascular glomus.
  • This neoplasm was firstly considered by Masson in 1924, and generally it has a solitary lesions but in some cases multiple lesions were described.
  • Differential diagnosis is usually made with Kaposi sarcoma and hemangiopericytoma.
  • The clinical case of a 65-year-old man with a glomus tumor of the lower lip is described.
  • [MeSH-major] Glomus Tumor / pathology. Lip Neoplasms / pathology

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  • (PMID = 16456522.001).
  • [ISSN] 0026-4970
  • [Journal-full-title] Minerva stomatologica
  • [ISO-abbreviation] Minerva Stomatol
  • [Language] eng; ita
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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50. Lü BJ, Zhu J, Gao L, Xie L, Xu JY, Lai MD: [Diagnostic accuracy and pitfalls in fine needle aspiration cytology of salivary glands: a study of 113 cases]. Zhonghua Bing Li Xue Za Zhi; 2005 Nov;34(11):706-10
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  • RESULTS: The FNAC diagnostic failure (2); non-neoplastic lesions (12); benign neoplasm (82) and malignant neoplasm (17).
  • The three inaccurately diagnosed cases of FNAC are, as follows: reactive lymphoid hyperplasia of lymph node mistaken as non-Hodgkin lymphoma, mucoepidermoid carcinoma diagnosed as "scanty atypical cells present" and primary lymphoepithelial carcinoma mistaken as benign lymphoepithelial lesion.
  • On the basis of FNAC, 97.4% (110 /113) were correctly depicted as benign (95/96; 99.0%) or malignant (15/17; 88.2%).
  • Furthermore, 90.3% (102 /113) (specificity = 91.9%; 102/111) were accurately diagnosed, including 91.7% (88/96) benign lesions (specificity = 92.6% ; 88/95) and 82.4% (14/17) malignant tumors (specificity = 87.5%; 14/16).
  • CONCLUSIONS: FNAC is reliable in distinguishing benign and malignant salivary gland lesions.
  • A specific cytologic diagnosis is often possible.
  • On the other hand, due to the pitfalls in cytologic diagnosis of certain salivary gland tumors, tissue biopsy for histologic examination may be necessary.
  • [MeSH-major] Carcinoma, Mucoepidermoid / pathology. Carcinoma, Squamous Cell / pathology. Salivary Gland Neoplasms / pathology. Salivary Glands / pathology
  • [MeSH-minor] Adenolymphoma / pathology. Adenoma / pathology. Adenoma, Pleomorphic / pathology. Adolescent. Adult. Aged. Biopsy, Fine-Needle. Carcinoma, Adenoid Cystic / pathology. Child. Diagnosis, Differential. Diagnostic Errors. Female. Humans. Male. Middle Aged. Parotid Neoplasms / pathology. Retrospective Studies. Submandibular Gland Neoplasms / pathology

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  • (PMID = 16536312.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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51. Xu AH, Yin YW, Chen FH: [The value of serum endostatin level in early diagnosis of lung cancer]. Zhonghua Yi Xue Za Zhi; 2006 Jul 18;86(27):1916-8
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  • [Title] [The value of serum endostatin level in early diagnosis of lung cancer].
  • OBJECTIVE: To investigate value of serum endostatin level in early diagnosis of lung cancer.
  • Twenty patients with benign lung disease and 20 normal persons were used as controls. RESULTS:.
  • (1) The serum endostatin level of the lung cancer patients was 10.71 +/- 9.99) ng/ml, significantly higher than those of the patients with benign lung diseases and the normal persons (4.79 +/- 1.23 ng/ml and 4.51 +/- 1.14 ng/ml, respectively, both P < 0.01). (2) The serum endostatin level of the lung cancer patients at the stage I and II were 13.63 +/- 13.13 ng/ml and 12.35 +/- 5.79 ng/ml respectively, booth significantly higher than that of the patients at the stage III (6.29 +/- 1.64, P = 0.023 and P = 0.023). (3) There were no significant differences in the serum endostatin level among the lung cancer patients with different pathological types. (4) The serum endostatin level of the lung cancer patients after chemotherapy was 7.83 +/- 1.48 ng/ml, significantly higher than that before the chemotherapy (5.59 +/- 1.74, P = 0.04).
  • CONCLUSION:. (1) Rising in lung cancer at stages I and II, level of serum may probably be used as the a sign in early diagnosis of lung cancer. (2) After chemotherapy the level of endostatin has a trend of rising.
  • The changes of serum endostatin level will be used as a sign in observation of treatment and prognosis.
  • [MeSH-major] Endostatins / blood. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / pathology. Aged. Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / pathology. Carcinoma, Squamous Cell / diagnosis. Carcinoma, Squamous Cell / pathology. Early Diagnosis. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Serologic Tests

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  • (PMID = 17064531.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Endostatins
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52. Hong KH, Yang YS: Intraoral approach for the treatment of submandibular salivary gland mixed tumors. Oral Oncol; 2008 May;44(5):491-5
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  • Pleomorphic adenoma represents a most common benign neoplasm of major salivary glands.
  • Most occurrences of this benign tumor in the submandibular gland have been treated surgically without difficulty via transcervical approach.
  • In this study, we introduced the intraoral approach for the removal of the submandibular mixed tumor.
  • During surgery the tumor and submandibular gland are easily dissected from surrounding tissue and removed through intraoral incision.
  • Early postoperative morbidity developed, such as a temporary paresis of lingual nerve and a temporary limitation of tongue movement, but recovered within a short-term period.
  • All patients were followed up for the recurrence of the tumor from 20 months to 10 years.
  • One patient showed a tumor recurrence at the early stage of this approach.
  • We propose that the benign mixed tumor of the submandibular gland could be removed easily via intraoral route without an external scar or nerve injury.
  • [MeSH-major] Adenoma, Pleomorphic / surgery. Postoperative Complications / prevention & control. Submandibular Gland / surgery. Submandibular Gland Neoplasms / surgery

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  • (PMID = 17827052.001).
  • [ISSN] 1368-8375
  • [Journal-full-title] Oral oncology
  • [ISO-abbreviation] Oral Oncol.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] England
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53. Weinberger CH, Dinulos JG, Perry AE: An enlarging tender nodule on the finger of a 4-year-old boy: an unusual presentation of infantile myofibromatosis. J Am Acad Dermatol; 2007 Aug;57(2 Suppl):S30-2
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  • [Title] An enlarging tender nodule on the finger of a 4-year-old boy: an unusual presentation of infantile myofibromatosis.
  • Infantile myofibromatosis is a benign neoplasm most commonly seen in the neonatal period through infancy.
  • We report a case of a 4-year-old boy who had a nodule on his left index finger.
  • [MeSH-major] Myofibromatosis / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 17637366.001).
  • [ISSN] 1097-6787
  • [Journal-full-title] Journal of the American Academy of Dermatology
  • [ISO-abbreviation] J. Am. Acad. Dermatol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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54. Poetker DM, Patel NJ, Kerschner JE: Cidofovir modulated gene expression in recurrent respiratory papillomatosis. Int J Pediatr Otorhinolaryngol; 2008 Sep;72(9):1385-92
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  • [Title] Cidofovir modulated gene expression in recurrent respiratory papillomatosis.
  • OBJECTIVE: Recurrent respiratory papillomatosis (RRP) is a benign aerodigestive tract neoplasm.
  • [MeSH-major] Antiviral Agents / pharmacology. Cytosine / analogs & derivatives. Organophosphonates / pharmacology. Papilloma / virology. Respiratory Tract Neoplasms / virology

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  • (PMID = 18620760.001).
  • [ISSN] 0165-5876
  • [Journal-full-title] International journal of pediatric otorhinolaryngology
  • [ISO-abbreviation] Int. J. Pediatr. Otorhinolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / Antiviral Agents; 0 / Interferon Regulatory Factor-7; 0 / Organophosphonates; 0 / RNA, Viral; 8J337D1HZY / Cytosine; JIL713Q00N / cidofovir
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55. Chen F, Li WM, Wang DM, Gao SS, Bao Y, Chen WB, Liu D: [Clinical value of combined detection of serum tumor markers in lung cancer diagnosis]. Sichuan Da Xue Xue Bao Yi Xue Ban; 2008 Sep;39(5):832-5
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  • [Title] [Clinical value of combined detection of serum tumor markers in lung cancer diagnosis].
  • OBJECTIVE: To investigate the clinical significance of a combination of several serum tumor markers in the diagnosis of lung cancer.
  • METHODS: Serum CEA, CA125, CA199, CYFRA21-1 and NSE were measured with RIA, chromatometrychemoluminescence, ELISA and biochemoluminescence methods respectively in 340 patients with lung cancers at different TNM stages, 120 patients with benign lung diseases, and 45 healthy people.
  • The sensitivities, specificities and accuracies of different combination of those markers for the diagnosis of lung cancers were compared.
  • The combination of several serum tumor markers had higher sensitivities than the single marker for the diagnosis of lung cancers.
  • CONCLUSION: Serum CEA, CA125, CA199, CYFRA21-1 and NSE are helpful markers for the diagnosis of lung cancer.
  • The combination of the markers can improve the sensitivity and accuracy of the diagnosis.
  • [MeSH-major] Antigens, Neoplasm / blood. Biomarkers, Tumor / blood. CA-125 Antigen / blood. Carcinoembryonic Antigen / blood. Keratins / blood. Lung Neoplasms / diagnosis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Carcinoma, Non-Small-Cell Lung / blood. Carcinoma, Non-Small-Cell Lung / diagnosis. Diagnosis, Differential. Female. Humans. Keratin-19. Male. Middle Aged. Small Cell Lung Carcinoma / blood. Small Cell Lung Carcinoma / diagnosis

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  • (PMID = 19024326.001).
  • [ISSN] 1672-173X
  • [Journal-full-title] Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
  • [ISO-abbreviation] Sichuan Da Xue Xue Bao Yi Xue Ban
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Biomarkers, Tumor; 0 / CA-125 Antigen; 0 / Carcinoembryonic Antigen; 0 / Keratin-19; 0 / antigen CYFRA21.1; 68238-35-7 / Keratins
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56. Barbara M, Ronchetti F, Manni V, Monini S: Double localization of a unilateral sporadic vestibular schwannoma. Acta Otorhinolaryngol Ital; 2008 Feb;28(1):34-7
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  • [Title] Double localization of a unilateral sporadic vestibular schwannoma.
  • Vestibular schwannoma may present as a sporadic or genetically-based multi-localized benign neoplasm of the internal auditory canal and/or cerebello-pontine angle region.
  • From these findings, the possibility of a unilateral multiple localization of a vestibular schwannoma is considered plausible within the range of clinical presentation, with negative genetic features.

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  • [Cites] Hum Genet. 1989 Apr;82(1):31-4 [2714777.001]
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  • (PMID = 18533554.001).
  • [ISSN] 0392-100X
  • [Journal-full-title] Acta otorhinolaryngologica Italica : organo ufficiale della Società italiana di otorinolaringologia e chirurgia cervico-facciale
  • [ISO-abbreviation] Acta Otorhinolaryngol Ital
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2640061
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57. Rodriguez FJ, Aubry MC, Tazelaar HD, Slezak J, Carney JA: Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma. Am J Surg Pathol; 2007 Dec;31(12):1844-53
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  • [Title] Pulmonary chondroma: a tumor associated with Carney triad and different from pulmonary hamartoma.
  • Forty-two patients with pulmonary cartilaginous tumors as a component of Carney triad were identified.
  • Hematoxylin and eosin-stained sections of the neoplasms were evaluated for a series of histologic features.
  • Their pulmonary neoplasm(s) were usually asymptomatic, often multiple, well circumscribed, medium-sized (mean diameter=2.8 cm), and composed almost exclusively of cartilage and bone surrounded by a fibrous pseudocapsule.
  • They showed no fat, smooth muscle or entrapped respiratory epithelium, tissues that were common in pulmonary hamartoma (P<0.0001).
  • The pulmonary neoplasms in the Carney triad are well-differentiated benign cartilaginous tumors that are best designated as chondromas.
  • They differ pathologically from pulmonary cartilaginous hamartomas on the basis of the presence of a thin fibrous pseudocapsule, frequent bone metaplasia, and calcification, and also the absence of entrapped epithelium and fat.
  • [MeSH-major] Chondroma / pathology. Hamartoma / pathology. Lung Neoplasms / pathology. Neoplasms, Multiple Primary / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Gastrointestinal Stromal Tumors / pathology. Humans. Male. Middle Aged. Paraganglioma, Extra-Adrenal / pathology

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  • (PMID = 18043038.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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58. Matsushima M, Asakura H, Sakamoto H, Horinaga M, Nakahira Y, Yanaihara H: Leiomyoma of the bladder presenting as acute urinary retention in a female patient: urodynamic analysis of lower urinary tract symptom; a case report. BMC Urol; 2010;10:13
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  • Benign mesenchymal tumors are rare.
  • Leiomyoma of the bladder is the most common benign neoplasm.
  • Evaluations including ultrasound, magnetic resonance imaging, cystoscopy, and urodynamics contributed to a diagnosis of leiomyoma of the bladder.
  • [MeSH-major] Leiomyoma / complications. Leiomyoma / physiopathology. Urinary Bladder Neoplasms / complications. Urinary Bladder Neoplasms / physiopathology. Urinary Retention / etiology. Urodynamics

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  • [Cites] Neurourol Urodyn. 2000;19(3):213-20 [10797578.001]
  • [Cites] Arch Esp Urol. 1991 Sep;44(7):795-8 [1953060.001]
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  • (PMID = 20684762.001).
  • [ISSN] 1471-2490
  • [Journal-full-title] BMC urology
  • [ISO-abbreviation] BMC Urol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2924335
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59. Marzo SJ, Zender CA, Leonetti JP: Facial nerve schwannoma. Curr Opin Otolaryngol Head Neck Surg; 2009 Oct;17(5):346-50
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  • PURPOSE OF REVIEW: The purpose of this review is to summarize the current literature on facial nerve schwannoma and make practical recommendations based on best practices for the management of this difficult but benign neoplasm.
  • The tumor is usually slow-growing and can involve multiple segments of the nerve.
  • As the tumor can involve multiple segments of the nerve, the surgeon attempting removal should be familiar with modern neurotological surgical techniques.
  • [MeSH-major] Cranial Nerve Neoplasms / surgery. Facial Nerve Diseases / surgery

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  • (PMID = 19561500.001).
  • [ISSN] 1531-6998
  • [Journal-full-title] Current opinion in otolaryngology & head and neck surgery
  • [ISO-abbreviation] Curr Opin Otolaryngol Head Neck Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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60. Sledzianowski JF, Duffas JP, Muscari F, Suc B, Fourtanier F: Risk factors for mortality and intra-abdominal morbidity after distal pancreatectomy. Surgery; 2005 Feb;137(2):180-5
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  • The diagnoses included pancreatic adenocarcinoma (n = 9), neuroendocrine neoplasms (n = 17), benign neoplasm (n = 26), pseudocyst (n = 4), chronic pancreatitis (n = 2), and other diagnoses (n = 3).
  • [MeSH-minor] Abdomen. Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Morbidity. Pancreatic Fistula / etiology. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy. Pancreatitis / surgery. Postoperative Complications / etiology. Postoperative Complications / mortality. Prospective Studies. Risk Factors

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  • (PMID = 15674199.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Xue Q, Wang J: Recurrent respiratory papillomatosis arising in trachea not affecting larynx. Intern Med; 2010;49(15):1649-51
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  • [Title] Recurrent respiratory papillomatosis arising in trachea not affecting larynx.
  • Recurrent respiratory papillomatosis (RRP) is an infrequent benign neoplasm commonly involving the upper respiratory tract with laryngeal predilection.
  • The diagnosis and treatment of this disease are challenging due to its nonspecific clinical presentations and recurrent nature.
  • Our experiences indicate that a high awareness of RRP and proper consideration in the right clinical context are prerequisites for early diagnosis, and a combination of multiple treatment modalities should be considered as a feasible treatment regimen.
  • [MeSH-major] Larynx. Tracheal Neoplasms / diagnosis
  • [MeSH-minor] Child. Humans. Male. Papillomavirus Infections / diagnosis. Papillomavirus Infections / prevention & control. Papillomavirus Infections / surgery. Respiratory Tract Infections / diagnosis. Respiratory Tract Infections / prevention & control. Respiratory Tract Infections / surgery. Secondary Prevention

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  • (PMID = 20686308.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] Recurrent respiratory papillomatosis
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62. Ardigo M, Buffon RB, Scope A, Cota C, Buccini P, Berardesca E, Pellacani G, Marghoob AA, Gill M: Comparing in vivo reflectance confocal microscopy, dermoscopy, and histology of clear-cell acanthoma. Dermatol Surg; 2009 Jun;35(6):952-9
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  • BACKGROUND: Clear cell acanthoma (CCA) is a rare, benign neoplasm of unknown etiology, whose dermoscopic and histological features have been previously described.
  • In some cases, diagnosis remains uncertain, and histological examination is needed.
  • All lesions were surgically excised to confirm the diagnosis and compare the morphological attributes under light microscopy with in vivo imaging.
  • RCM appears to be a useful tool for in vivo diagnosis of CCA and may help avoid unnecessary biopsies.
  • [MeSH-major] Acanthoma / pathology. Dermoscopy / methods. Histological Techniques / methods. Microscopy, Confocal / methods. Skin Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Reproducibility of Results

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  • (PMID = 19397663.001).
  • [ISSN] 1524-4725
  • [Journal-full-title] Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
  • [ISO-abbreviation] Dermatol Surg
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] United States
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63. Rohrbach JM, Grüb M, Schlote T: [Neoplastic secondary glaucomas]. Klin Monbl Augenheilkd; 2005 Oct;222(10):788-96
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  • The frequency of IOP-elevation is mainly dependent on the biologic behaviour of the neoplasm (benign / malignant), its dimensions, localization, and its ability to provoke secondary changes like retinal detachment, hemorrhages, inflammation, and necroses.
  • As intraocular tumours may have pressure-lowering effects too, eyes bearing a tumour may also be hypotonic or normotonic inspite of a "glaucomatous chamber angle morphology".
  • [MeSH-major] Eye Neoplasms / diagnosis. Eye Neoplasms / therapy. Glaucoma / diagnosis. Glaucoma / therapy

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  • (PMID = 16240271.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 93
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64. Aytac-Yazicioglu D, Eren H, Görgün S: Peripheral odontogenic myxoma located on the maxillary gingiva: report of a case and review of the literature. Oral Maxillofac Surg; 2008 Sep;12(3):167-71
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  • [Title] Peripheral odontogenic myxoma located on the maxillary gingiva: report of a case and review of the literature.
  • BACKGROUND: Odontogenic myxoma is a rare, benign neoplasm and is often located in the maxillofacial region centrally most common in the mandible.
  • Soft tissue localization that can be classified as a peripheral myxoma is rarely seen than the central localization.
  • [MeSH-major] Gingival Neoplasms / pathology. Myxoma / pathology. Odontogenic Tumors / pathology

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  • (PMID = 18642035.001).
  • [ISSN] 1865-1550
  • [Journal-full-title] Oral and maxillofacial surgery
  • [ISO-abbreviation] Oral Maxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 39
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65. Nikitakis NG, Argyris P, Sklavounou A, Papadimitriou JC: Oral myoepithelioma of soft tissue origin: report of a new case and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 2010 Nov;110(5):e48-51
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  • [Title] Oral myoepithelioma of soft tissue origin: report of a new case and literature review.
  • Oral myoepithelioma of soft tissue origin, an entity distinct from myoepithelioma of salivary glands, constitutes an extremely rare benign neoplasm, with only 1 previously published case, affecting the tongue of a 22-year-old woman.
  • Ectomesenchymal chondromyxoid tumour (ECT) also is a very rare benign neoplasm of the oral cavity that has a strong predilection for the anterior dorsum of the tongue.
  • The aim of this paper is to report a new case of STM affecting the dorsal tongue of a 45-year-old man.
  • [MeSH-major] Myoepithelioma / diagnosis. Tongue Neoplasms / diagnosis
  • [MeSH-minor] Actins / analysis. Antigens, CD57 / analysis. Cell Nucleus / ultrastructure. Chromatin / ultrastructure. Cytoplasm / ultrastructure. Desmin / analysis. Diagnosis, Differential. Glial Fibrillary Acidic Protein / analysis. Humans. Male. Middle Aged. Mouth Mucosa / pathology. Muscle, Skeletal / pathology. Neoplasms, Complex and Mixed / diagnosis. S100 Proteins / analysis. Vimentin / analysis

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  • [Copyright] Copyright © 2010 Mosby, Inc. All rights reserved.
  • (PMID = 20955943.001).
  • [ISSN] 1528-395X
  • [Journal-full-title] Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
  • [ISO-abbreviation] Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD57; 0 / Chromatin; 0 / Desmin; 0 / Glial Fibrillary Acidic Protein; 0 / S100 Proteins; 0 / Vimentin
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66. Wang W, Quan CB, Li N, Wang XJ, Song JY, Jia SL, Lin MG: [Diagnosis of pleural cavity extraskeletal osteosarcoma: a case report and literature review]. Zhonghua Jie He He Hu Xi Za Zhi; 2010 Mar;33(3):202-5
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  • [Title] [Diagnosis of pleural cavity extraskeletal osteosarcoma: a case report and literature review].
  • OBJECTIVE: To describe the manifestations and diagnosis of pleural cavity extraskeletal osteosarcoma (ESO).
  • RESULTS: Chest CT of a middle-aged man revealed an enormous heterogeneous neoplasm, about 10.9 cm x 9.2 cm x 17.7 cm in size, in the left pleural cavity.
  • There was abundant calcification in the tumor, with signs of invasion into the diaphragm and the pleura.
  • Osteosarcoma was confirmed by pathological study after surgical resection of the tumor.
  • The differential diagnosis includes benign and malignant diseases of the thorax.

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  • (PMID = 20450640.001).
  • [ISSN] 1001-0939
  • [Journal-full-title] Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
  • [ISO-abbreviation] Zhonghua Jie He He Hu Xi Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] China
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67. De Wever W, Stroobants S, Coolen J, Verschakelen JA: Integrated PET/CT in the staging of nonsmall cell lung cancer: technical aspects and clinical integration. Eur Respir J; 2009 Jan;33(1):201-12
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  • This improvement can result in the detection of lesions initially not seen on CT or PET, a more precise location of lesions, a better characterisation of the lesion as benign or malignant and a better differentiation between tumour and surrounding structures.
  • [MeSH-major] Carcinoma, Non-Small-Cell Lung / diagnosis. Lung Neoplasms / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Humans. Neoplasm Staging. Reproducibility of Results

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  • (PMID = 19118231.001).
  • [ISSN] 1399-3003
  • [Journal-full-title] The European respiratory journal
  • [ISO-abbreviation] Eur. Respir. J.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
  • [Number-of-references] 65
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68. Jaiswal AK, Jaiswal S, Sahu RN, Das KB, Jain VK, Behari S: Choroid plexus papilloma in children: Diagnostic and surgical considerations. J Pediatr Neurosci; 2009 Jan;4(1):10-6
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  • BACKGROUND: Choroid plexus papilloma (CPP) is a benign neoplasm that arises from the ventricular choroid plexus.
  • CONCLUSIONS: Coagulation of the tumor under constant irrigation to shrink and excise it in toto, avoids excessive bleeding during surgery.
  • The vascular pedicle supplying the tumor should be adequately dealt with during the last part of tumor removal as retraction of a bleeding pedicle may result in ventricular hemorrhage and brain edema.

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  • (PMID = 21887168.001).
  • [ISSN] 1817-1745
  • [Journal-full-title] Journal of pediatric neurosciences
  • [ISO-abbreviation] J Pediatr Neurosci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3162829
  • [Keywords] NOTNLM ; Choroid plexus / intraventricular tumor / tumor
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69. Filipovski V, Banev S, Janevska V, Dukova B: Granular cell tumor of the breast: a case report and review of literature. Cases J; 2009;2:8551
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  • [Title] Granular cell tumor of the breast: a case report and review of literature.
  • A 22-year-old female patient presented with a breast mass lesion with a clinical suspicion of a fibroadenoma.
  • Histological evaluation revealed a rare benign neoplasm - granular cell tumor.Granular cell tumor is rare neoplasm that may arise in virtually any body site, and in 5% it occurs in the breast.
  • The histogenesis of this tumor is still rather controversial and currently the most acceptable theory is a Schwann cell origin.
  • The main histological feature is granular cytoplasm of the tumor cells.From a clinical point of view there is a similarity between granular cell tumor and mammary carcinoma on mammography and ultrasound.
  • Pathohistologically, sometimes, differential diagnostic difficulties exist concerning apocrine carcinoma, histiocytic lesions and metastatic neoplasms.

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  • (PMID = 19918386.001).
  • [ISSN] 1757-1626
  • [Journal-full-title] Cases journal
  • [ISO-abbreviation] Cases J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2769456
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70. Haresh KP, Prabhakar R, Rath GK, Sharma DN, Julka PK, Subramani V: Adenoid cystic carcinoma of the trachea treated with PET-CT based intensity modulated radiotherapy. J Thorac Oncol; 2008 Jul;3(7):793-5
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  • Primary tumors of the trachea are rare and are usually malignant in adults and benign in children.
  • Because there was a compromised respiratory reserve due to pneumonectomy we decided to keep the radiation dose to the remaining lung as low as possible.
  • [MeSH-major] Carcinoma, Adenoid Cystic / radiotherapy. Positron-Emission Tomography. Radiotherapy, Intensity-Modulated. Tomography, X-Ray Computed. Tracheal Neoplasms / radiotherapy
  • [MeSH-minor] Fluorodeoxyglucose F18. Humans. Male. Middle Aged. Neoplasm, Residual / radiography. Neoplasm, Residual / radionuclide imaging. Neoplasm, Residual / radiotherapy. Radiography, Interventional. Radiopharmaceuticals

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  • (PMID = 18594327.001).
  • [ISSN] 1556-1380
  • [Journal-full-title] Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
  • [ISO-abbreviation] J Thorac Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
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71. Dhouib M, Briki S, Ben Mahfoudh K, Karray F, Boudawara T, Mnif J, Abdelmoula M: [Melanotic schwannoma of the temporozygomatic region]. Rev Stomatol Chir Maxillofac; 2007 Apr;108(2):139-42
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  • [Transliterated title] Schwannome mélanocytique de la région temporozygomatique.
  • INTRODUCTION: Melanotic schwannoma is a rare benign tumor, which arises from nerve sheath cells.
  • Outcome was favourable after tumor resection.
  • DISCUSSION: This benign neoplasm occurs pronominally in spinal nerve roots.
  • [MeSH-major] Neurilemmoma / pathology. Skull Neoplasms / pathology

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  • (PMID = 17363019.001).
  • [ISSN] 0035-1768
  • [Journal-full-title] Revue de stomatologie et de chirurgie maxillo-faciale
  • [ISO-abbreviation] Rev Stomatol Chir Maxillofac
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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72. Alebouyeh M, Moussavi F, Tabari AK, Vossough P: Aggressive intra-abdominal fibromatosis in children and response to chemotherapy. Pediatr Hematol Oncol; 2005 Sep;22(6):447-51
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  • Intra-abdominal fibromatosis (IAF) is a rare benign neoplasm arising from the abdominal fibrous tissue, mostly in the mesentery.
  • Within 6 months after initial presentation, he underwent 4 subsequent abdominal explorations for diagnosis, tumor reduction, and intestinal obstructions.
  • Due to accelerated tumor growth and deteriorated general condition, as a last resort, a chemotherapy trial with vincristin and methotrexate was carried out.
  • This regimen proved to be effective in reducing the tumor burden and improving the patient's general condition.
  • Outcome of IAF depends on early diagnosis and complete tumor resection, and, if indicated, timely employment of neo/adjuvant chemotherapy.
  • [MeSH-minor] Child, Preschool. Humans. Male. Methotrexate / administration & dosage. Tumor Burden / drug effects. Vincristine / administration & dosage

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  • (PMID = 16169811.001).
  • [ISSN] 0888-0018
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 5J49Q6B70F / Vincristine; YL5FZ2Y5U1 / Methotrexate
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73. Laspas F, Roussakis A, Papadopoulos S, Fanariotis I, Kritikos N, Kehagias D: Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings. Ultrasound Obstet Gynecol; 2010 May;35(5):617-9
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  • [Title] Mixed tumor of the vagina: sonographic and magnetic resonance imaging findings.
  • Mixed tumor of the vagina is a rare benign neoplasm that is composed of epithelial and mesenchymal cells.
  • The majority of tumors are asymptomatic and simple tumor excision is curative.
  • On T2-weighted images the mass appeared as a homogeneous hyperintense lesion, while on T1-weighted images it was difficult to discern the mass from the vaginal wall.
  • [MeSH-major] Vaginal Neoplasms / diagnosis

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  • [Copyright] Copyright 2009 ISUOG. Published by John Wiley & Sons, Ltd.
  • (PMID = 20069660.001).
  • [ISSN] 1469-0705
  • [Journal-full-title] Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology
  • [ISO-abbreviation] Ultrasound Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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74. Ozbudak IH, Dertsiz L, Bassorgun CI, Ozbilim G: Giant cystic chondroid hamartoma of the lung. J Pediatr Surg; 2008 Oct;43(10):1909-11
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  • Pulmonary hamartoma composed of an abnormal mixture of mesenchymal elements is the most common benign neoplasm in the lung.
  • We suggest that giant cystic pulmonary hamartoma should be included in the differential diagnosis of large intrathoracic masses in children.
  • [MeSH-minor] Adipose Tissue / pathology. Calcinosis / pathology. Calcinosis / radiography. Calcinosis / surgery. Cartilage / pathology. Child. Diagnosis, Differential. Epithelium / pathology. Humans. Incidental Findings. Lung Neoplasms / diagnosis. Male. Thoracotomy. Tomography, X-Ray Computed

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  • (PMID = 18926231.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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75. Kaur A, Agrawal A, Agrawal PK, Goel MM: Lacrimal canalicular obstruction by cysticercus cellulosae. Orbit; 2006 Jun;25(2):163-5
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  • The diagnosis was established by histopathological examination of the cyst, surgically removed from the above patient with a suspected benign neoplasm in the lacrimal passage.

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  • (PMID = 16754231.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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76. Gurrera A, Brancato F, Puzzo L, Magro G, Greco P: [Squamous cell carcinoma in situ arising in ovarian mature cystic teratoma]. Pathologica; 2008 Feb;100(1):9-12
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  • Mature cystic teratoma is a benign neoplasm, but malignant transformation of one component may occur in 2% of cases.
  • [MeSH-major] Carcinoma, Squamous Cell / pathology. Neoplasms, Multiple Primary / pathology. Ovarian Neoplasms / pathology. Teratoma / pathology


77. Soudack M, Guralnik L, Ben-Nun A, Berkowitz D, Postovsky S, Vlodavsky E, Engel A: Imaging features of posterior mediastinal chordoma in a child. Pediatr Radiol; 2007 May;37(5):492-7
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  • Evaluation by CT revealed a low-density posterior mediastinal mass initially diagnosed as benign tumor.
  • [MeSH-major] Chordoma / diagnosis. Mediastinal Neoplasms / diagnosis. Mediastinum / diagnostic imaging. Neoplasm Recurrence, Local / diagnosis
  • [MeSH-minor] Child, Preschool. Cough / etiology. Diagnosis, Differential. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Respiratory Sounds. Tomography, X-Ray Computed

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  • (PMID = 17345078.001).
  • [ISSN] 0301-0449
  • [Journal-full-title] Pediatric radiology
  • [ISO-abbreviation] Pediatr Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
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78. Yu K, Liu Y, Wang H, Hu S, Long C: Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases. Interact Cardiovasc Thorac Surg; 2007 Oct;6(5):636-9
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  • Of primary cardiac tumors, the incidence of benign neoplasm was much higher than malignant masses (90.6% vs. 9.4%, P<0.01).
  • The most common benign cardiac tumor was myxoma (86.8%).
  • Benign non-myxoma tumors are more likely to occur in the ventricular (64.3%).
  • [MeSH-major] Asian Continental Ancestry Group / statistics & numerical data. Heart Neoplasms. Hemangiosarcoma. Lipoma. Mesenchymoma. Myxoma. Rhabdomyoma
  • [MeSH-minor] Adolescent. Adult. Age Distribution. Aged. Child. Child, Preschool. China / epidemiology. Female. Humans. Incidence. Infant. Male. Middle Aged. Neoplasm Metastasis. Prevalence. Retrospective Studies. Sex Distribution

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  • (PMID = 17670730.001).
  • [ISSN] 1569-9285
  • [Journal-full-title] Interactive cardiovascular and thoracic surgery
  • [ISO-abbreviation] Interact Cardiovasc Thorac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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79. Kneitz H, Weyandt G, Meissner C, Gebhart E, Bröcker EB: Dermal schwannoma (neurilemmoma): a peculiar foreign body reaction? Am J Dermatopathol; 2010 Jun;32(4):367-9
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  • Schwannoma is usually a subcutaneous benign neoplasm that derives from nerve sheath.
  • Solitary schwannoma has a traumatic origin in some cases, and rarely occur as a part of neurofibromatosis or schwannomatosis.
  • To our knowledge, we present the first case of a painful dermal schwannoma in association to foreign material.
  • [MeSH-major] Foreign-Body Reaction / pathology. Neurilemmoma / pathology. Skin Neoplasms / pathology

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  • (PMID = 20216197.001).
  • [ISSN] 1533-0311
  • [Journal-full-title] The American Journal of dermatopathology
  • [ISO-abbreviation] Am J Dermatopathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 9004-34-6 / Cellulose
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80. Scherpereel A, Grigoriu B, Conti M, Gey T, Grégoire M, Copin MC, Devos P, Chahine B, Porte H, Lassalle P: Soluble mesothelin-related peptides in the diagnosis of malignant pleural mesothelioma. Am J Respir Crit Care Med; 2006 May 15;173(10):1155-60
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  • [Title] Soluble mesothelin-related peptides in the diagnosis of malignant pleural mesothelioma.
  • BACKGROUND: Diagnosis of malignant pleural mesothelioma is a challenging issue.
  • Potential markers in mesothelioma diagnosis include soluble mesothelin-related peptides (SMRPs) and osteopontin, but no subsequent validation has been published yet.
  • METHODS: We prospectively evaluated SMRPs in serum and pleural effusion from patients with mesothelioma (n = 74), pleural metastasis of carcinomas (n = 35), or benign pleural lesions associated with asbestos exposure (n = 28), recruited when first suspected for mesothelioma.
  • FINDINGS: Mean serum SMRP level was higher in patients with mesothelioma (2.05 +/- 2.57 nM/L [median +/- interquartile range]) than in patients with metastasis (1.02 +/- 1.79 nM/L) or benign lesions (0.55 +/- 0.59 nM/L).
  • The area under the receiver operating characteristic curve (AUC) for serum SMRP was 0.872 for differentiating mesothelioma and benign lesions, cut-off = 0.93 nM/L (sensitivity = 80%, specificity = 82.6%).
  • SMRP values in pleural fluid were higher than in serum in all groups (mesothelioma: 46.1 +/- 83.2 nM/L; benign lesions: 6.4 +/- 11.1 nM/L; metastasis: 6.36 +/- 21.73 nM/L).
  • The AUC for pleural SMRP-differentiating benign lesions and mesothelioma was 0.831, cut-off = 10.4 nM/L (sensitivity = 76.7%, specificity = 76.2%).
  • INTERPRETATION: We show that SMRPs may be a promising marker for mesothelioma diagnosis when measured either in serum or pleural fluid.
  • [MeSH-major] Asbestosis / pathology. Membrane Glycoproteins / metabolism. Mesothelioma / pathology. Pleural Effusion, Malignant / diagnosis. Pleural Neoplasms / pathology. Sialoglycoproteins / metabolism
  • [MeSH-minor] Aged. Analysis of Variance. Area Under Curve. Biomarkers, Tumor / analysis. Diagnosis, Differential. Disease Progression. Female. GPI-Linked Proteins. Humans. Male. Middle Aged. Neoplasm Staging. Osteopontin. Prognosis. Prospective Studies. Sensitivity and Specificity. Solubility. Survival Analysis

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  • (PMID = 16456138.001).
  • [ISSN] 1073-449X
  • [Journal-full-title] American journal of respiratory and critical care medicine
  • [ISO-abbreviation] Am. J. Respir. Crit. Care Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / SPP1 protein, human; 0 / Sialoglycoproteins; 0 / mesothelin; 106441-73-0 / Osteopontin
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81. Catez E, Tatnga Ngatcha V, Catez S: An unusual right atrial mass: case report and review of the literature. Acta Cardiol; 2010 Aug;65(4):477-80
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  • CT scan and cardiac MRI showed a mass appending on the right atrial free wall above the tricuspid annulus, enhanced by contrast, without any thoracic or abdominal extension, and confirmed the diagnosis of a tumour.
  • This small primary cardiac benign neoplasm usually occurs on cardiac valves, but can also appear, as described here, in a non-valvular localization.
  • The diagnosis is, up to now, usually made by echocardiography, but CT and MR imaging could lead to a better description and analysis of this underestimated tumour.
  • [MeSH-major] Heart Atria / pathology. Heart Neoplasms / diagnosis
  • [MeSH-minor] Aged, 80 and over. Contrast Media. Diagnosis, Differential. Echocardiography. Electrocardiography. Female. Humans. Magnetic Resonance Imaging. Tomography, X-Ray Computed

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  • (PMID = 20821944.001).
  • [ISSN] 0001-5385
  • [Journal-full-title] Acta cardiologica
  • [ISO-abbreviation] Acta Cardiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 11
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82. Xiao H, Gong S, Nie X, Guo C, Zhong G: [Ossifying fibroma of the temporal bone]. Lin Chuang Er Bi Yan Hou Ke Za Zhi; 2006 Oct;20(19):868-70
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  • OBJECTIVE: To describe the clinical presentation of ossifying fibroma of the temporal bone, and to discuss its diagnosis and treatment.
  • Frozen section evaluation during operation was not definitive but suggested benign nature in histology.
  • The tumor was fully resected.
  • RESULT: The final pathological report indicated the stromal cells were negative for S-100 protein and epithelia membrane antigen (EMA), supporting the diagnosis of ossifying fibroma.
  • One-year follow-up showed the sealed EAC was satisfactory with complete interior and no tumor recurred.
  • CONCLUSION: Ossifying fibroma of the temporal bone is a rare entity, which is a benign neoplasm but may show an aggressive behavior by compression and encroachment upon adjacent structures.
  • [MeSH-major] Bone Neoplasms. Fibroma, Ossifying. Temporal Bone / pathology

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  • (PMID = 17168109.001).
  • [Journal-full-title] Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
  • [ISO-abbreviation] Lin Chuang Er Bi Yan Hou Ke Za Zhi
  • [Language] chi
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] China
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83. Cho YJ, Won JB, Byeon SH, Yang WI, Koh HJ, Kwon OW, Lee SC: A choroidal schwannoma confirmed by surgical excision. Korean J Ophthalmol; 2009 Mar;23(1):49-52
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  • Histologically, the tumor was composed of a mixture of cellular solid components (Antoni A) and loose myxoid components (Antoni B).
  • The tumor was eventually diagnosed as a schwannoma.
  • In the case of atypical findings for a malignant melanoma, a benign neoplasm should be included in the differential diagnosis.
  • [MeSH-major] Choroid / pathology. Choroid Neoplasms / diagnosis. Eye Enucleation / methods. Neurilemmoma / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging

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  • (PMID = 19337481.001).
  • [ISSN] 2092-9382
  • [Journal-full-title] Korean journal of ophthalmology : KJO
  • [ISO-abbreviation] Korean J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2655748
  • [Keywords] NOTNLM ; Enucleation / Schwannoma / Sclerouvectomy
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84. Hong R, Lim SC: Granular cell tumor of the cecum with extensive hyalinization and calcification: a case report. World J Gastroenterol; 2009 Jul 14;15(26):3315-8
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  • [Title] Granular cell tumor of the cecum with extensive hyalinization and calcification: a case report.
  • A granular cell tumor (GCT) is a benign neoplasm of unclear histogenesis that is generally believed to be of nerve sheath origin.
  • We experienced a case of GCT that arose in the cecum of a 55-year-old man.
  • In addition to the tumor, endoscopic examination revealed the presence of a 5-mm-polyp in the descending colon and multiple tiny polyps in the sigmoid colon and rectum.
  • Histological examination demonstrated a cecal tumor 1.5 cm x 1.0 cm x 0.7 cm with a hard consistency; in cut sections, mixed cells with yellowish and whitish portions were seen.
  • The tumor was located between the mucosa and subserosa, and was composed of plump histiocyte-like tumor cells with abundant granular eosinophilic cytoplasm, which were immunoreactive for S-100 protein, vimentin, neuron-specific enolase, inhibin-alpha and calretinin.
  • The tumor showed extensive hyalinization and focal dystrophic calcification.
  • Extensive hyalinization and calcification showing involution of tumor cells suggest benign clinical behavior of GCT.
  • [MeSH-major] Calcinosis / pathology. Cecum / pathology. Granular Cell Tumor / pathology. Hyalin / metabolism
  • [MeSH-minor] Biomarkers, Tumor. Calbindin 2. Colorectal Neoplasms / diagnosis. Colorectal Neoplasms / pathology. Humans. Male. Middle Aged. Phosphopyruvate Hydratase. S100 Calcium Binding Protein G. S100 Proteins. Vimentin

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  • [Cites] Ugeskr Laeger. 2006 May 22;168(21):2080-1 [16768929.001]
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  • (PMID = 19598311.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / S100 Proteins; 0 / Vimentin; EC 4.2.1.11 / Phosphopyruvate Hydratase
  • [Other-IDs] NLM/ PMC2710791
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85. Shahoon H, Esmaeili M, Nikhalat M, Farokhi E: Odontogenic Fibromyxoma and Odontogenic Cyst in an Eight year old Boy: Three-year Follow-up. J Dent Res Dent Clin Dent Prospects; 2009;3(3):103-5
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  • Odontogenic fibromyxoma is a rare and locally-invasive benign neoplasm found exclusively in the jaws.

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  • (PMID = 23230495.001).
  • [ISSN] 2008-210X
  • [Journal-full-title] Journal of dental research, dental clinics, dental prospects
  • [ISO-abbreviation] J Dent Res Dent Clin Dent Prospects
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
  • [Other-IDs] NLM/ PMC3517275
  • [Keywords] NOTNLM ; Mandible / odontogenic cyst / odontogenic fibromyxoma
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86. Singh R, Jain M, Siwach R, Rohilla RK, Kaur K: Unusual presentation of bizarre parosteal osteochondromatous lesion of the second toe (Nora's lesion). Foot Ankle Spec; 2010 Dec;3(6):347-51
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  • Bizarre parosteal osteochondromatous proliferation (BPOP) of bone is a rare benign neoplasm.
  • Although local excision of the tumor is the treatment of choice, the authors resorted to ray excision, as gangrenous changes and ulceration were present and there was the possibility of malignant change.
  • [MeSH-major] Bone Neoplasms / pathology. Foot Ulcer / pathology. Osteochondroma / pathology. Periosteum / pathology. Toes / pathology

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  • (PMID = 20624925.001).
  • [ISSN] 1938-7636
  • [Journal-full-title] Foot & ankle specialist
  • [ISO-abbreviation] Foot Ankle Spec
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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87. de Koning HD, Bovenschen HJ: Two adjacent nodules on the leg. Dermatol Online J; 2010;16(6):13
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  • Poroma is a rare benign neoplasm (derived from the intraepidermal part of the eccrine or apocrine duct), which may clinically mimic malignant tumors such as (amelanotic) malignant melanoma and porocarcinoma.
  • Histopathological examination is the key to the correct diagnosis, which is illustrated in the present case, in which a pigmented basal cell carcinoma and a poroma are in close proximity to each other.
  • Despite a clinical differential diagnosis of melanoma, histopathology showed the typical characteristics of a poroma, a rare but much more favorable tumor.
  • [MeSH-major] Carcinoma, Basal Cell / diagnosis. Leg. Poroma / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 20579468.001).
  • [ISSN] 1087-2108
  • [Journal-full-title] Dermatology online journal
  • [ISO-abbreviation] Dermatol. Online J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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88. Saussez S, Mahillon V, Blaivie C, Haller A, Chantrain G, Thill MP: Aggressive pilomatrixoma of the infra-auricular area: a case report. Auris Nasus Larynx; 2005 Dec;32(4):407-10
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  • Although pilomatrixomas are well known among dermatologists and dermatopathologists, head and neck surgeons confronted with these lesions in the infra-auricular region do not consider this benign neoplasm in the differential diagnosis.
  • Aggressive pilomatrixoma is a benign tumor of the hair matrix cells affecting mainly children.
  • We report the case of a 15-year-old Turkish boy suffering from an aggressive pilomatrixoma of the infra-auricular region and review the literature about this unclear entity.
  • [MeSH-major] Ear Neoplasms / pathology. Hair Diseases / pathology. Pilomatrixoma / pathology. Skin Neoplasms / pathology
  • [MeSH-minor] Adolescent. Diagnosis, Differential. Humans. Male. Neoplasm Staging

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  • (PMID = 16198080.001).
  • [ISSN] 0385-8146
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Number-of-references] 13
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89. van der Kwast TH: How to combine the molecular profile with the clinicopathological profile of urothelial neoplastic lesions. Scand J Urol Nephrol Suppl; 2008 Sep;(218):175-84
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  • The current World Health Organization (WHO) 2004 classification of urothelial neoplasms was based on an attempt to reconcile molecular-genetic and pathology findings.
  • It is more likely that urothelial papilloma is a benign neoplasm sharing mutations in the fibroblast growth factor-3 gene with seborrhoeic keratosis, allegedly its epidermal counterpart.
  • Genetic alterations in papillary urothelial neoplasia of low malignant potential are identical to those found in non-invasive low-grade papillary urothelial carcinoma, implying that they are within a spectrum of the same neoplasm.
  • Expression profiling data corroborate the view that (secondary) carcinoma in situ may act not only as a precursor lesion for invasive non-papillary urothelial carcinoma, but also as a precursor for non-muscle-invasive papillary urothelial carcinoma.
  • Given the significant molecular genetic differences between non-invasive and invasive papillary urothelial carcinomas and their analogy with exophytic neoplastic precursor lesions in other organ systems, an alternative nomenclature is proposed, replacing papillary urothelial carcinoma with papillary intraurothelial neoplasm for the non-invasive (pTa) papillary carcinomas.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Carcinoma, Transitional Cell / metabolism. Urinary Bladder Neoplasms / metabolism
  • [MeSH-minor] DNA, Neoplasm / analysis. Genetic Markers / genetics. Humans. Molecular Probe Techniques. Prognosis

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  • (PMID = 18815932.001).
  • [ISSN] 0300-8886
  • [Journal-full-title] Scandinavian journal of urology and nephrology. Supplementum
  • [ISO-abbreviation] Scand J Urol Nephrol Suppl
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Sweden
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm; 0 / Genetic Markers
  • [Number-of-references] 57
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90. Zhang H, Feng Y, Jiang L: [Tumorectomy by trans-oral approach of macrosis benign neoplasms in parapharyngeal space (reports of 6 cases)]. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi; 2010 Jun;24(12):556-8
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  • [Title] [Tumorectomy by trans-oral approach of macrosis benign neoplasms in parapharyngeal space (reports of 6 cases)].
  • OBJECTIVE: To discuss the feasibility of tumorectomy by transoral approach of macrosis benign neoplasms in parapharyngeal space.
  • METHOD: Retrospective analyze 6 patients of macrosis benign neoplasms in parapharyngeal space from January 2005 to May 2008, and all neoplasms were removed by transoral approach.
  • RESULT: The neoplasms were all removed completely and successfully, and postoperative recovery were good and no complications were found.
  • CONCLUSION: Preoperative imaging examination is very important for diagnosis and treatment of benign neoplasm in parapharyngeal space, which is especially helpful to understand the scope of the tumor, and the relationship with carotid artery and vein.
  • On this basis, it is feasible to select the appropriate cases to resect huge benign neoplasm in parapharyngeal space.
  • [MeSH-major] Neoplasms / surgery. Oropharynx / surgery. Otorhinolaryngologic Surgical Procedures / methods. Pharyngeal Neoplasms / surgery

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  • (PMID = 20806862.001).
  • [ISSN] 1001-1781
  • [Journal-full-title] Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery
  • [ISO-abbreviation] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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91. Hong SK, Lee HJ, Cho SH, Seo JK, Lee D, Sung HS: Syringomas Treated by Intralesional Insulated Needles without Epidermal Damage. Ann Dermatol; 2010 Aug;22(3):367-9
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  • Syringoma is a benign adnexal tumor derived from intradermal eccrine ducts; it predominantly occurs in women at puberty or later in life.
  • Although syringoma is a common benign neoplasm, there have been no effective therapies for its removal.

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  • [Cites] Dermatol Surg. 2007 Mar;33(3):310-3 [17338688.001]
  • [Cites] J Clin Pathol. 2007 Feb;60(2):145-59 [16882695.001]
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  • (PMID = 20711282.001).
  • [ISSN] 2005-3894
  • [Journal-full-title] Annals of dermatology
  • [ISO-abbreviation] Ann Dermatol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2917699
  • [Keywords] NOTNLM ; Insulated needle / Syringoma
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92. Koseoglu RD, Ozkan N, Filiz NO, Kayaoglu HA, Aydin M, Culha EN, Ersoy OF: Intranodal palisaded myofibroblastoma; a case report and review of the literature. Pathol Oncol Res; 2009 Jun;15(2):297-300
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  • Intranodal palisaded myofibroblastoma (IPM) also called as intranodal hemorrhagic spindle cell tumor with amianthoid fibers is a distinctive and rare mesenchymal neoplasm of lymph nodes.
  • In contrast to Kaposi's sarcoma, it behaves in a benign fashion and does not need any further therapy except total surgical resection of the mass.
  • This neoplasm has a great predilection for the inguinal region.
  • The lesion presents typically as a unilateral, painless, solitary mass.
  • We present a 43-year-old-male patient with IPM and discuss histological, immunohistochemical features and pathogenesis of this rare benign neoplasm.
  • [MeSH-major] Carcinoma / pathology. Lymph Nodes / pathology. Neoplasms, Muscle Tissue / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Humans. Immunoenzyme Techniques. Male

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  • (PMID = 18991023.001).
  • [ISSN] 1219-4956
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 20
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93. Juhlin J, Eiholm S: [Rhabdomyoma in the head and neck region]. Ugeskr Laeger; 2009 Mar 30;171(14):1194
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  • Extracardiac rhabdomyoma is an extremely uncommon benign neoplasm with skeletal muscle differentiation which usually involves the head and neck region.
  • We report two cases of extracardiac adult rhabdomyoma affecting adult patients and initially seen as slowly-growing, indolent neoplasms.
  • Complete local excision without radical surgery was performed and histological findings confirmed the diagnosis of adult rhabdomyoma.
  • Adult rhabdomyomas should be considered as a differential diagnosis in the head and neck region.
  • [MeSH-major] Head and Neck Neoplasms / diagnosis. Rhabdomyoma / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged

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  • (PMID = 19338741.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
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94. Singaraju S, Wanjari SP, Parwani RN: Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature. J Oral Maxillofac Pathol; 2010 Jan;14(1):19-23
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  • [Title] Odontogenic myxoma of the maxilla: A report of a rare case and review of the literature.
  • Odontogenic myxoma represents an uncommon benign neoplasm comprising of 3-6% of all odontogenic tumors.
  • This article presents a rare case of odontogenic myxoma occurring in the maxilla of a 7-year-old male patient with a brief review of the pathogenesis, clinical, radiological, histopathological, ultrastructural and immunohistochemical characteristics of odontogenic myxoma.

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  • (PMID = 21180454.001).
  • [ISSN] 1998-393X
  • [Journal-full-title] Journal of oral and maxillofacial pathology : JOMFP
  • [ISO-abbreviation] J Oral Maxillofac Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2995999
  • [Keywords] NOTNLM ; Odontogenic myxomas / fibromyxoma / odontogenic tumors
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95. Peter Klussmann J, Wittekindt C, Florian Preuss S, Al Attab A, Schroeder U, Guntinas-Lichius O: High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases. Acta Otolaryngol; 2006 Dec;126(11):1213-7
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  • [Title] High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases.
  • CONCLUSIONS: We identified smoking as a significant risk factor for multilocular Warthin tumor development.
  • OBJECTIVES: Warthin tumor is a common benign neoplasm of the parotid gland.
  • PATIENTS AND METHODS: A total of 185 consecutive patients treated for Warthin tumor were included.
  • Bilateral Warthin tumor was seen in 17% of patients.
  • The median time period for second contralateral tumor development was 7 years.
  • [MeSH-major] Adenolymphoma / etiology. Neoplasms, Multiple Primary / etiology. Parotid Neoplasms / etiology. Smoking / adverse effects

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  • (PMID = 17050316.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Norway
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96. de Moraes M, de Matos FR, de Carvalho CP, de Medeiros AM, de Souza LB: Sialolipoma in minor salivary gland: case report and review of the literature. Head Neck Pathol; 2010 Sep;4(3):249-52
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  • Sialolipoma is a rare benign neoplasm characterized by a well-circumscribed mass composed of neoplastic mature adipose tissue and non-neoplastic salivary gland elements.
  • Microscopically, the tumor was well-circumscribed consisting of lobular proliferation of the lipomatous tissue with thin fibrous tissue septa containing clustered salivary gland elements.
  • The definitive diagnosis was sialolipoma.
  • The age distribution was from 27 to 84 years (mean, 61.6 years) and the tumor size ranged from 0.9 to 4 cm (mean, 1.7 cm).
  • The most frequently reported clinical presentation was of a painless swelling (56.3%).
  • [MeSH-major] Lipoma / pathology. Salivary Gland Neoplasms / pathology

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  • (PMID = 20563675.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2923305
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97. Lee TK, Chuang ST, Netto GJ: Conventional prostatic adenocarcinoma arising in a multilocular prostatic cystadenoma. Pathol Int; 2010 May;60(5):413-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Multilocular prostatic cystadenoma is a rare benign neoplasm located between the bladder and the rectum.
  • These are prostatic tissue and have been shown to harbor high-grade intraepithelial neoplasia and likely susceptible to the same disease processes seen in the prostate gland.
  • [MeSH-major] Adenocarcinoma / pathology. Cystadenoma / pathology. Neoplasms, Multiple Primary / pathology. Prostatic Neoplasms / pathology
  • [MeSH-minor] Aged. Biomarkers, Tumor / metabolism. Cystadenocarcinoma / diagnosis. Diagnosis, Differential. Humans. Male. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 20518893.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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98. Haro R, González-Guerra E, Fariña MC, Martín-Moreno L, Requena L: [Trichilemmal horn: a new case and review of the literature]. Actas Dermosifiliogr; 2009 Jan-Feb;100(1):65-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Cuerno tricolémico: presentación de un nuevo caso y revisión de la literatura.
  • Trichilemmal horn, or trichilemmal keratosis, is an uncommon benign neoplasm of follicular lineage with trichilemmal differentiation.
  • The essential characteristics of this tumor are its clinical presentation in the form of a cutaneous horn with trichilemmal keratinization apparent in the histology study (with a hyperplastic epithelium giving rise to dense, orthokeratotic eosinophilic keratin).
  • We present a new case of this type of tumor in an 82-year-old woman who developed a solitary lesion on her scalp after surgical removal of a trichilemmal cyst.
  • On the basis of the pathology report, the tumor was diagnosed as trichilemmal horn.
  • We review the 33 reports of this tumor in the literature to date.
  • [MeSH-major] Epidermal Cyst / complications. Keratosis / diagnosis. Scalp Dermatoses / diagnosis
  • [MeSH-minor] Aged, 80 and over. Female. Humans. Keratins / analysis. Postoperative Complications / diagnosis. Postoperative Complications / pathology

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  • (PMID = 19268114.001).
  • [ISSN] 0001-7310
  • [Journal-full-title] Actas dermo-sifiliográficas
  • [ISO-abbreviation] Actas Dermosifiliogr
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article; Review
  • [Publication-country] Spain
  • [Chemical-registry-number] 68238-35-7 / Keratins
  • [Number-of-references] 10
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99. Jadhav MN, Yelikar BR, Patil SB: Epithelioid angiomyolipoma of the kidney: a case report. Indian J Pathol Microbiol; 2007 Apr;50(2):338-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Renal angiomyolipoma is a distinctive benign neoplasm that occurs either sporadically or in patients with tuberous sclerosis complex.
  • Immunohistochemistry confirmed the diagnosis of angiomyolipoma.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Antigens, Neoplasm. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Melanoma-Specific Antigens. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 17883064.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Chemical-registry-number] 0 / Antigens, Neoplasm; 0 / Melanoma-Specific Antigens; 0 / Neoplasm Proteins
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100. Ravindra S, Suguna BV: Cytomorphology of tubular adenoma breast--a case report. Indian J Pathol Microbiol; 2006 Apr;49(2):267-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Tubular adenoma a 'pure adenoma' is a benign neoplasm of breast presenting clinically like fibroadenoma.
  • [MeSH-major] Adenoma / pathology. Breast Neoplasms / pathology
  • [MeSH-minor] Adult. Biopsy, Fine-Needle. Diagnosis, Differential. Female. Fibroadenoma / pathology. Fibrocystic Breast Disease / pathology. Humans

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  • (PMID = 16933735.001).
  • [ISSN] 0377-4929
  • [Journal-full-title] Indian journal of pathology & microbiology
  • [ISO-abbreviation] Indian J Pathol Microbiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] India
  • [Number-of-references] 7
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