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1. Cerantola Y, Vaucher L, Doerfler A, Meuwly JY, Jichlinski P: [Benefits of ultrasonography in kidney and testicular-sparing surgery]. Rev Med Suisse; 2010 Dec 8;6(274):2365-8
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  • [Title] [Benefits of ultrasonography in kidney and testicular-sparing surgery].
  • [Transliterated title] Apport de l'utltrasonographie dans la chirurgie d'épargne du rein et du testicule.
  • Renal and testicular cancers account for 4% and 1% of all malignancies, respectively.
  • Their prevalence has increased over the past years and is related to the widespread use of medical imaging and the incidental findings of small asymptomatic tumors on computed tomography scanners and ultrasounds examinations.
  • The urologist faces the dilemma of overtreating benign asymptomatic lesions with radical surgery.
  • Recent studies have shown that recurrence rates are often similar between organ-sparing and radical surgery for small kidney or testicular tumors.
  • This article discusses the role of ex-vivo peroperative ultrasonography in predicting negative surgical margins during kidney- and testicular-sparing surgery.
  • [MeSH-major] Kidney Neoplasms / surgery. Kidney Neoplasms / ultrasonography. Testicular Neoplasms / surgery. Testicular Neoplasms / ultrasonography

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  • (PMID = 21290869.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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2. Minervini A, Serni S, Giubilei G, Lanzi F, Vittori G, Lapini A, Carini M: Multiple ipsilateral renal tumors: retrospective analysis of surgical and oncological results of tumor enucleation vs radical nephrectomy. Eur J Surg Oncol; 2009 May;35(5):521-6
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  • [Title] Multiple ipsilateral renal tumors: retrospective analysis of surgical and oncological results of tumor enucleation vs radical nephrectomy.
  • AIMS: To evaluate the role of nephron-sparing surgery (NSS) compared to radical nephrectomy (RN) for treating multiple ipsilateral renal tumors.
  • Thirty-four patients were diagnosed as having at least one ipsilateral smaller solid lesion associated with the primary RCC: 22 had RN while 12 had NSS for tumor enucleation.
  • RESULTS: All patients who had NSS had tumors confined within the kidney, as did 82% of patients treated with RN.
  • The sole presence of concomitant accompanying benign histology to the primary RCC was diagnosed in 20% of patients.
  • Tumor stage was significantly associated with tumor-specific survival (TSS) in the RN group (p<0.001).
  • None of the patients who had tumor enucleation had positive surgical margins.
  • Two patients recurred locally after NSS, elsewhere in the kidney, resulting in a crude ipsilateral recurrence rate of 17%.
  • The analysis of TSS for patients with multiple ipsilateral tumors with a pT1 primary lesion showed no statistically significant differences between patients who had RN or NSS.
  • CONCLUSIONS: For patients with multiple ipsilateral renal tumors, 20% of the satellite lesions are benign and 6% develop a contralateral metachronous recurrence.
  • [MeSH-major] Carcinoma, Renal Cell / surgery. Kidney Neoplasms / surgery. Neoplasms, Multiple Primary / surgery. Nephrectomy / methods
  • [MeSH-minor] Aged. Disease Progression. Female. Humans. Male. Middle Aged. Neoplasm Staging. Prognosis. Retrospective Studies. Risk. Survival Analysis. Treatment Outcome

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  • (PMID = 18640001.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] England
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3. Descotes JL, Doublet JD: [Renal imaging and biopsy for diagnosis of renal masses]. Ann Urol (Paris); 2006 Nov;40 Suppl 3:S86-90
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  • [Title] [Renal imaging and biopsy for diagnosis of renal masses].
  • [Transliterated title] Apport de l'imagerie et des biopsies dans le diagnostic des masses solides du rein.
  • Incidental diagnosis of renal tumors is more and more common.
  • Imaging is of paramount importance for the caracterization of these tumors.
  • Ultrasound allows the diagnosis of solid tumors, thereby excluding cysts.
  • Renal cancer is the main etiology, but benign tumors can be suspected in small tumors less than 4 cm.
  • Angiomyolipoma and oncocytoma are the more frequent benign tumors.
  • Angiolipoma can be diagnosed with CT-scan, but there are no radiological criteria for the diagnosis of oncocytoma.
  • Renal percutaneous biopsy can be helpful in selected cases.
  • It is recommended for bilateral tumors, or when a renal metastasis is suspected.
  • For small lesions with radiological features consistent with the diagnosis of benign tumor, renal biopsy can confirm this diagnosis and lead surgical abstention.
  • Nevertheless, few centers have a regular practise of renal biopsy.
  • [MeSH-major] Kidney Neoplasms / diagnosis

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  • (PMID = 17366862.001).
  • [ISSN] 0003-4401
  • [Journal-full-title] Annales d'urologie
  • [ISO-abbreviation] Ann Urol (Paris)
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 23
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4. Mattar K, Jewett MA: Watchful waiting for small renal masses. Curr Urol Rep; 2008 Jan;9(1):22-5
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  • [Title] Watchful waiting for small renal masses.
  • Small renal masses (SRMs; < 4 cm in diameter) account for most renal tumors treated today.
  • Incidental early detection of SRMs by abdominal imaging results in favorable grade and stage migration to renal cell carcinoma, and also increases detection of benign renal tumors.
  • [MeSH-major] Kidney Neoplasms / pathology. Kidney Neoplasms / therapy

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  • [Cites] J Natl Cancer Inst. 2006 Sep 20;98(18):1331-4 [16985252.001]
  • [Cites] J Urol. 2006 Oct;176(4 Pt 1):1317-20; discussion 1320 [16952619.001]
  • [Cites] Eur Urol. 2004 Sep;46(3):327-30 [15306102.001]
  • [Cites] Cancer. 2005 Nov 15;104(10):2116-23 [16208703.001]
  • [Cites] Cancer. 2003 Dec 1;98(11):2329-34 [14635066.001]
  • [Cites] BJU Int. 2005 Dec;96(9):1224-9 [16287435.001]
  • [Cites] J Urol. 2000 Oct;164(4):1153-9 [10992356.001]
  • [Cites] Urology. 2003 Nov;62(5):827-30 [14624902.001]
  • [Cites] J Urol. 2006 Feb;175(2):459-62 [16406971.001]
  • [Cites] J Urol. 1999 May;161(5):1475-9 [10210376.001]
  • [Cites] Eur Urol. 1995;27(4):319-23 [7656910.001]
  • [Cites] Cancer. 2007 May 1;109(9):1763-8 [17351954.001]
  • [Cites] Cancer. 2002 Feb 1;94(3):658-64 [11857297.001]
  • [Cites] J Urol. 2002 Mar;167(3):1257-62 [11832709.001]
  • [Cites] J Urol. 2006 Sep;176(3):896-9 [16890647.001]
  • [Cites] J Urol. 2000 Jun;163(6):1665-70 [10799156.001]
  • [Cites] JAMA. 1999 May 5;281(17):1628-31 [10235157.001]
  • [Cites] J Urol. 2004 Sep;172(3):863-6 [15310984.001]
  • [Cites] Urology. 1998 Feb;51(2):203-5 [9495698.001]
  • [Cites] J Urol. 2000 Feb;163(2):426-30 [10647646.001]
  • [Cites] J Urol. 2007 May;177(5):1692-6; discussion 1697 [17437785.001]
  • [Cites] J Urol. 2006 Feb;175(2):425-31 [16406965.001]
  • [Cites] J Urol. 2003 Dec;170(6 Pt 1):2217-20 [14634382.001]
  • [Cites] BJU Int. 2002 Sep;90(4):358-63 [12175389.001]
  • [Cites] J Urol. 2005 Jan;173(1):42-7 [15592022.001]
  • [Cites] Int J Urol. 2001 Sep;8(9):473-7 [11683965.001]
  • [Cites] J Urol. 2001 Jul;166(1):54-8 [11435822.001]
  • [Cites] J Urol. 2000 Feb;163(2):442-5 [10647650.001]
  • [Cites] BJU Int. 2000 Nov;86(7):782-9 [11069401.001]
  • [Cites] J Urol. 2005 Jun;173(6):1903-7 [15879772.001]
  • [Cites] Urology. 2004 Jul;64(1):49-52 [15245934.001]
  • [Cites] J Urol. 1993 Jan;149(1):1-7 [8417184.001]
  • [Cites] Urology. 2006 Jul;68(1 Suppl):7-13 [16857454.001]
  • [Cites] Cancer. 2004 Feb 15;100(4):738-45 [14770429.001]
  • [Cites] J Urol. 2002 Jan;167(1):57-60 [11743275.001]
  • [Cites] J Urol. 1969 Mar;101(3):297-301 [5765875.001]
  • [Cites] Eur Urol. 1999 Oct;36(4):298-302 [10473988.001]
  • [Cites] J Urol. 1988 Sep;140(3):487-90 [3411657.001]
  • [Cites] Radiology. 1995 Dec;197(3):589-97 [7480724.001]
  • [Cites] Eur Urol. 2006 Sep;50(3):521-8; discussion 529 [16530322.001]
  • (PMID = 18366970.001).
  • [ISSN] 1534-6285
  • [Journal-full-title] Current urology reports
  • [ISO-abbreviation] Curr Urol Rep
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 44
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5. Aksu G, Ulutin C, Fayda M, Saynak M: Cerebellar and multiple spinal hemangioblastomas and intraventricular meningioma managed with subtotal resection and external beam radiotherapy; report of a case with literature review. J BUON; 2005 Jul-Sep;10(3):405-9
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  • Hemangioblastomas are cystic, highly vascular benign neoplasms that constitute 1.5-2.5% of all intracranial tumors and 7-10% of primary posterior fossa tumors.
  • They occur sporadically (80%) or in association with von Hippel-Lindau (VHL) disease (20%).
  • This disease consists of multiple intracranial, retinal and spinal hemangioblastomas, pheochromocytoma, retinal angiomas, pancreatic cysts, renal cell carcinomas and adrenal tumors.
  • There was a positive family history (mother and brother) of VHL disease.
  • However, since hemangioblastoma is a highly vascular tumor and local invasion of critical structures is frequent and multifocality is often a characteristic of the hemangioblastomas that are associated with VHL disease, subtotal excision is frequent and adjuvant therapies such as external beam radiotherapy or stereotactic radiosurgery represent a reasonable treatment in such cases.

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  • (PMID = 17357198.001).
  • [ISSN] 1107-0625
  • [Journal-full-title] Journal of B.U.ON. : official journal of the Balkan Union of Oncology
  • [ISO-abbreviation] J BUON
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Greece
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6. Lin YS, Chung HJ, Lin AT, Huang WJ, Huang YH, Lin TP, Chen KK: Laparoscopic partial nephrectomy: Taipei veterans general hospital experience. J Chin Med Assoc; 2010 Jul;73(7):364-8
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  • BACKGROUND: Laparoscopic partial nephrectomy (LPN) is a definitive therapy in patients with a small renal tumor.
  • The follow-up data, including local recurrence, distant metastasis, and renal function, were recorded.
  • The mean tumor diameter was 3.81 cm (range, 2.0-7.5 cm).
  • There were 17 (40.0%) benign cases and 26 (56.5%) renal cell carcinomas, which were stage pT1a in 19 (73.1%) cases, pT1b in 5 (19.2%) cases, pT2 in 1 (3.8%) case, and pT3a in 1 (3.8%) case.
  • The function of the operated kidney was reduced by a mean of 21.9% at 3 months (p < 0.05) and 27.7% at 6 months (p < 0.05) postoperatively.
  • CONCLUSION: Although our warm ischemic time and operative time were longer than those of other LPN studies, the interim results of our oncologic and renal functional outcomes were encouraging.
  • In addition, based on postoperative renal function, LPN does not significantly influence long-term renal function.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Creatinine / blood. Female. Hospitals, Veterans. Humans. Kidney / physiopathology. Male. Middle Aged. Retrospective Studies

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  • [Copyright] 2010 Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20688302.001).
  • [ISSN] 1728-7731
  • [Journal-full-title] Journal of the Chinese Medical Association : JCMA
  • [ISO-abbreviation] J Chin Med Assoc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Chemical-registry-number] AYI8EX34EU / Creatinine
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7. Schlomer B, Figenshau RS, Yan Y, Venkatesh R, Bhayani SB: Pathological features of renal neoplasms classified by size and symptomatology. J Urol; 2006 Oct;176(4 Pt 1):1317-20; discussion 1320
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pathological features of renal neoplasms classified by size and symptomatology.
  • PURPOSE: We examined the relationship between tumor size and pathological findings in a contemporary series of surgical renal lesions and we characterized the relationship of incidental and symptomatic tumors to pathological findings.
  • MATERIALS AND METHODS: We retrospectively reviewed the records of patients treated surgically for renal lesions suspicious for malignancy between March 2000 and May 2005.
  • RESULTS: A total of 349 renal masses from 331 patients were identified.
  • Of the 349 renal masses 56 (16.0%) were benign, 289 (82.8%) were renal cell carcinoma and 4 (1.1%) were other malignancies.
  • The percent of malignant tumors increased from 72.1% for those less than 2 cm to 93.7% for those greater than 7 cm (OR 1.39, 95% CI 1.17 to 1.65).
  • Of the 349 renal masses 258 (73.9%) were discovered incidentally and 91 (26.1%) were symptomatic.
  • Mean size of incidental and symptomatic tumors was 3.7 and 6.2 cm, respectively (p < 0.001).
  • When comparing T1 incidental and symptomatic tumors, there was no significant difference in the overall frequency of malignancy.
  • When comparing T2 incidental and symptomatic tumors, the groups had similar malignancy rates (90.9% and 100%, respectively, p = 0.16).
  • CONCLUSIONS: Smaller renal tumors are more likely to be benign or be a lower grade of malignancy.
  • T1 renal tumors are more likely to be detected incidentally than T2 tumors.
  • When T1 incidental and symptomatic tumors were compared, there was no difference between the malignancy rates.
  • However, when T2 incidental and symptomatic tumors were compared, symptomatic tumors were more likely to be high grade malignancy.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Angiomyolipoma / pathology. Carcinoma, Renal Cell / pathology. Cysts / pathology. Kidney Neoplasms / pathology. Leiomyoma / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Incidental Findings. Male. Middle Aged. Neoplasm Staging. Retrospective Studies

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  • (PMID = 16952619.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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8. Volmar KE, Cummings TJ, Wang WH, Creager AJ, Tyler DS, Xie HB: Clear cell hidradenoma: a mimic of metastatic clear cell tumors. Arch Pathol Lab Med; 2005 May;129(5):e113-6
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  • [Title] Clear cell hidradenoma: a mimic of metastatic clear cell tumors.
  • Clear cell hidradenoma is a benign skin appendage tumor that may mimic conventional-type renal cell carcinoma.
  • Histologically, clear cell hidradenoma contains small ductular lumens, focal apocrine and squamoid change, and a less prominent vascular pattern than renal cell carcinoma.
  • Furthermore, immunohistochemical studies can aid in distinguishing the 2 tumors.
  • Knowing the cytologic features of primary skin adnexal neoplasms helps distinguish them from cutaneous metastases, which are more commonly referred for fine-needle aspiration biopsy evaluation.
  • Detailed clinical history, physical findings, and ancillary studies are essential for correct diagnosis and categorization of these tumors.
  • We report the rare case of a patient with renal cell carcinoma who underwent excision of an axillary clear cell hidradenoma, which was clinically suggestive of cutaneous metastatic disease.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Neoplasms, Multiple Primary / diagnosis. Sweat Gland Neoplasms / diagnosis
  • [MeSH-minor] Axilla. Biomarkers, Tumor / analysis. Diagnosis, Differential. Humans. Immunohistochemistry. Lymph Nodes / pathology. Lymph Nodes / surgery. Male. Middle Aged. Mitotic Index. Neoplasm Metastasis / diagnosis. Treatment Outcome

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  • (PMID = 15859654.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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9. Raj GV, Bach AM, Iasonos A, Korets R, Blitstein J, Hann L, Russo P: Predicting the histology of renal masses using preoperative Doppler ultrasonography. J Urol; 2007 Jan;177(1):53-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Predicting the histology of renal masses using preoperative Doppler ultrasonography.
  • PURPOSE: Traditional imaging techniques cannot differentiate among benign, indolent and malignant renal neoplasms.
  • Since conventional clear cell carcinomas are highly vascular, we used preoperative color and/or power Doppler ultrasonography to evaluate the association between vascular flow in a renal mass and surgical pathology.
  • Any detection of flow in the renal mass on color Doppler ultrasonography was defined as vascular flow.
  • RESULTS: Of 299 renal lesions in the retrospective cohort 210 (70%) had evidence of vascular flow, including 156 of 169 conventional clear cell carcinomas (92%) (p <0.0001).
  • This finding was validated prospectively in 97 patients.
  • Vascular flow was detected in 54 of 65 renal masses (83%) with conventional clear cell histology (p <0.0001), which was associated with an OR of 10.8 (95% CI 4.0-29.0; p <0.0001).
  • A nomogram incorporating vascular flow on color Doppler ultrasonography and clinical parameters may aid in the preoperative characterization of renal lesions.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Carcinoma, Renal Cell / ultrasonography. Kidney Neoplasms / pathology. Kidney Neoplasms / ultrasonography. Ultrasonography, Doppler
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Preoperative Care. Prospective Studies. Retrospective Studies

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  • (PMID = 17161999.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Compérat E, Couturier J, Peyromaure M, Cornud F, Vieillefond A: Benign mixed epithelial and stromal tumor of the kidney (MEST) with cytogenetic alteration. Pathol Res Pract; 2005;200(11-12):865-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mixed epithelial and stromal tumor of the kidney (MEST) with cytogenetic alteration.
  • Benign mixed epithelial and stromal tumor of the kidney (MEST) is a new, rare entity.
  • These tumors are composed of two components: a stromal and an epithelial one.
  • [MeSH-major] Chromosomes, Human, Pair 1 / genetics. Chromosomes, Human, Pair 19 / genetics. Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology. Translocation, Genetic
  • [MeSH-minor] Actins / analysis. Adult. Biomarkers, Tumor / analysis. Carcinoma, Renal Cell / diagnosis. Cysts / pathology. Desmin / analysis. Diagnosis, Differential. Humans. Keratins / analysis. Male. Nephrectomy. Stromal Cells / chemistry. Stromal Cells / pathology

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  • (PMID = 15792135.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Actins; 0 / Biomarkers, Tumor; 0 / Desmin; 68238-35-7 / Keratins
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11. Imanaka M, Iida K, Takahashi K, Tsuji K, Nishizawa H, Fukuoka H, Takeno R, Takahashi Y, Okimura Y, Kaji H, Chihara K: The N131S mutation in the von Hippel-Lindau gene in a Japanese family with pheochromocytoma and hemangioblastomas. Endocr J; 2006 Dec;53(6):819-27
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • von Hippel-Lindau (VHL) disease (VHLD) is a hereditary autosomal dominant syndrome that causes various benign and malignant tumors.
  • VHLD is caused by mutations in the VHL tumor suppressor gene.
  • Here, we report a mutation in the VHL gene in a Japanese family with VHLD type 2A, characterized by pheochromocytoma (PHE), and hemangioblastomas (HAB) in both the retina and thoracic spinal cord but without renal cell carcinoma (RCC).
  • We also identified somatic loss of heterozygosity (LOH) at chromosome 3p25-26 in the adrenal tumor of the patient.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Cerebellar Neoplasms / genetics. Hemangioblastoma / genetics. Mutation. Pheochromocytoma / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 17001110.001).
  • [ISSN] 0918-8959
  • [Journal-full-title] Endocrine journal
  • [ISO-abbreviation] Endocr. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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12. Treuthardt C, Doerfler A, Jichlinski P: [Laparoscopic nephrectomy: technical aspects]. Rev Med Suisse; 2008 Dec 3;4(182):2636-40
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  • The laparoscopic approach has emerged as a valid option for surgical management of kidney cancer, as well as a few benign pathologies.
  • Long-term oncologic outcomes of patients treated laparoscopically for kidney tumors are similar to those of open surgery.
  • [MeSH-major] Kidney Neoplasms / surgery. Laparoscopy / methods. Nephrectomy / methods

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  • (PMID = 19160995.001).
  • [ISSN] 1660-9379
  • [Journal-full-title] Revue médicale suisse
  • [ISO-abbreviation] Rev Med Suisse
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Switzerland
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13. Agrawal S, Jha MS, Khurana N, Ansari MS, Dubey D, Srivastava A, Kapoor R, Kumar A, Jain M, Mandhani A: Nephron sparing surgery: A single institution experience. Indian J Urol; 2007 Jan;23(1):23-7
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  • OBJECTIVE: To report our experience in managing various benign and malignant renal tumors with nephron-sparing surgery.
  • Patient and tumor-related characteristics, treatment modality and complications were noted.
  • RESULTS: There were 26 patients (29 renal units), including three with bilateral lesions who underwent nephron-sparing surgery.
  • Mean tumor size was 4.7 cm (range 2-7.5 cm).
  • Histopathological profile revealed 13 (44.8%) benign lesions which included angiomyolipoma (eight), simple cyst (two), cortical adenoma (one), metanephric adenoma (one) and myelolipoma (one).
  • The remaining 16 (55.2%) malignant lesions included renal cell carcinoma (15) and metastatic adenocarcinoma (one).
  • CONCLUSIONS: Nephron-sparing surgery is a safe and effective alternative to nephrectomy in both benign and malignant lesions of the kidney.

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  • [Cites] J Urol. 2000 Feb;163(2):442-5 [10647650.001]
  • [Cites] Urology. 2001 Feb;57(2):252-6 [11182331.001]
  • [Cites] J Urol. 1999 Jan;161(1):33-4; discussion 34-5 [10037361.001]
  • [Cites] BJU Int. 2005 Mar;95 Suppl 2:35-40 [15720333.001]
  • [Cites] J Clin Oncol. 1999 Sep;17(9):2868-75 [10561364.001]
  • [Cites] Cancer. 1997 Sep 1;80(5):992-3 [9307205.001]
  • [Cites] J Urol. 1998 Sep;160(3 Pt 1):674-8 [9720519.001]
  • [Cites] J Urol. 1994 May;151(5):1177-80 [8158754.001]
  • [Cites] J Urol. 1995 May;153(5):1409-14 [7714953.001]
  • [Cites] Urology. 1995 Jan;45(1):34-40; discussion 40-1 [7817478.001]
  • [Cites] Urology. 1980 Mar;15(3):219-28 [7361352.001]
  • [Cites] Indian J Cancer. 2004 Jul-Sep;41(3):99-103 [15472406.001]
  • [Cites] Urology. 2004 Jul;64(1):31-4 [15245928.001]
  • [Cites] Urology. 2002 Jun;59(6):816-20 [12031359.001]
  • [Cites] Urology. 1999 Dec;54(6):994-8 [10604696.001]
  • (PMID = 19675756.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2721489
  • [Keywords] NOTNLM ; Kidney / kidney diseases / nephron sparing surgery
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14. Jung SJ, Shen SS, Tran T, Jun SY, Truong L, Ayala AG, Ro JY: Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literature. Hum Pathol; 2008 Mar;39(3):463-8
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  • [Title] Mixed epithelial and stromal tumor of kidney with malignant transformation: report of two cases and review of literature.
  • We present 2 cases of mixed epithelial and stromal tumor of the kidney with sarcomatous transformation.
  • The resected tumor involved the right renal parenchyma, measuring 13.0 x 8.0 x 4.0 cm, and extended to perirenal adipose tissue.
  • The tumor measured 6.0 x 5.5 x 4.0 cm, with an intact capsule at the upper pole.
  • Both tumors showed a well-circumscribed, multilocular, cystic, and focally solid mass.
  • Sections of both tumors revealed benign and malignant components.
  • The benign component consisted of multilocular cysts and fibrous stroma with a focally ovarian stromalike component.
  • We report 2 additional cases of sarcomatous transformation in mixed epithelial and stromal tumor of the kidney.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Carcinoma / metabolism. Carcinoma / pathology. Epithelial Cells / metabolism. Epithelial Cells / pathology. Female. Humans. Immunohistochemistry. Middle Aged. Stromal Cells / metabolism. Stromal Cells / pathology

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  • (PMID = 18261632.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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15. Dong D, Li H, Yan W, Xu W, Lu L, Zeng Z: The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney. J Hypertens; 2010 Mar;28(3):628-32
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  • [Title] The diagnosis and surgical management of juxtaglomerular cell tumor of the kidney.
  • Juxtaglomerular cell tumor (JCT) of the kidney is a rare benign renal neoplasm.
  • Four cases of JCT of the kidney have been diagnosed and treated surgically in our hospital from January 2005 to August 2008.
  • Pathological examination confirmed the final diagnosis of JCT of the kidney.
  • JCT of the kidney should be kept in mind because they represent a surgically curable cause of secondary hypertension.
  • [MeSH-major] Juxtaglomerular Apparatus / pathology. Kidney Neoplasms / diagnosis. Kidney Neoplasms / surgery

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  • (PMID = 20051908.001).
  • [ISSN] 1473-5598
  • [Journal-full-title] Journal of hypertension
  • [ISO-abbreviation] J. Hypertens.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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16. Gupta NP, Ishwar R, Kumar A, Dogra PN, Seth A: Renal tumors presentation: changing trends over two decades. Indian J Cancer; 2010 Jul-Sep;47(3):287-91
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  • [Title] Renal tumors presentation: changing trends over two decades.
  • PURPOSE: We have analyzed the changing trends in surgical treatment of renal tumors over the last 2 decades with regard to age incidence, presentation, incidental detection, and histopathology.
  • MATERIALS AND METHODS: Records of renal tumors were analyzed from January 1, 1988 to December 31, 2007.
  • RESULTS: Out of 811 renal tumors, 17.63% cases were benign and 82.37% were malignant.
  • The cases of surgically treated tumors increased in number from 103 to 304 in cohort 4.
  • Among the histopathologies, clear cell carcinoma was most common (73.35 %), but Fuhrman grading showed a trend toward more cases detected with grade 1 and 2 in cohort 4; 23.73% and 61.86%, respectively, as compared with 15.85% and 45.12% in cohort 1 (P = 0.001); more T1 tumors were detected (63.42% in cohort 4 as compared with 41.46% in cohort 1).
  • CONCLUSIONS: A majority of renal tumors presented as symptomatic tumors.
  • Recently, tumors are being detected at an early stage and grade; in the younger patients, with an increasing trend of laparoscopic and open NSS.
  • [MeSH-major] Kidney Neoplasms / epidemiology. Kidney Neoplasms / surgery. Nephrectomy. Sarcoma, Clear Cell / epidemiology. Sarcoma, Clear Cell / surgery

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  • (PMID = 20587904.001).
  • [ISSN] 1998-4774
  • [Journal-full-title] Indian journal of cancer
  • [ISO-abbreviation] Indian J Cancer
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] India
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17. Patel NP, Geisinger KR, Zagoria RJ, Bergman S: Fine needle aspiration biopsy of metanephric adenoma: a case report. Acta Cytol; 2009 May-Jun;53(3):327-31
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  • BACKGROUND: Metanephric adenoma (MA) is a rare, benign renal neoplasm.
  • Regarding treatment, radioflrequency ablation (RFA) is an emerging alternative to surgical resection of renal neoplasms in appropriately selected patients.
  • CASE: A 49-year-old woman had a 3.3-cm cortical mass in the left kidney.
  • The aspirate smears displayed multiple aggregates of benign-appearing, tightly packed and overlapping nuclei surrounded by basement membrane- type material.
  • Although the differential diagnosis included adult Wilms' tumor and papillary renal cell carcinoma, the bland morphology and IHC staining pattern strongly favored a neoplasm consistent with MA.
  • CONCLUSION: FNAB can be used to diagnose most renal neoplasms.
  • A diagnosis of MA can be suggested on FNAB in the context of appropriate cytomorphology, IHC staining and cytogenetic analysis.
  • [MeSH-major] Adenoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Antigens, CD57 / analysis. Biomarkers, Tumor / analysis. Biopsy, Fine-Needle. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Catheter Ablation / methods. Diagnosis, Differential. Female. Humans. Middle Aged. Minimally Invasive Surgical Procedures. Treatment Outcome. WT1 Proteins / analysis. Wilms Tumor / diagnosis

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  • (PMID = 19534278.001).
  • [ISSN] 0001-5547
  • [Journal-full-title] Acta cytologica
  • [ISO-abbreviation] Acta Cytol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antigens, CD57; 0 / Biomarkers, Tumor; 0 / WT1 Proteins
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18. Compérat E, Camparo P, Vieillefond A: [WHO classification 2004: tumors of the kidneys]. J Radiol; 2006 Sep;87(9):1015-24
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  • [Title] [WHO classification 2004: tumors of the kidneys].
  • [Transliterated title] Classification anatomo pathologique des tumeurs du rein.
  • New entities, confirmed either by cytogenetic findings or by new molecular markers, have been included in the WHO 2004 renal tumor classification.
  • Moreover, imaging improvements provide a better radiologic description of tumors.
  • We will especially insist on the following entities: multilocular clear cell renal carcinoma, Xp11 translocation carcinoma, low-grade mucinous tubular carcinoma, epithelioid angiomyolipoma, and benign mixed epithelial and stromal tumor.
  • We also discuss the new concept of hybrid oncocytoma and chromophobe renal cell carcinoma, as well as the Birt-Hogg-Dube syndrome, which is associated with kidney tumors.
  • [MeSH-major] International Classification of Diseases. Kidney Neoplasms / classification. Kidney Neoplasms / pathology

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  • (PMID = 16936625.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] France
  • [Number-of-references] 21
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19. Venkatesh R, Weld K, Ames CD, Figenshau SR, Sundaram CP, Andriole GL, Clayman RV, Landman J: Laparoscopic partial nephrectomy for renal masses: effect of tumor location. Urology; 2006 Jun;67(6):1169-74; discussion 1174
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  • [Title] Laparoscopic partial nephrectomy for renal masses: effect of tumor location.
  • OBJECTIVES: To report our single institutional experience of laparoscopic partial nephrectomy (LPN) for enhancing renal masses and evaluate outcomes and histopathologic findings with respect to the location of the renal mass.
  • METHODS: A retrospective review of LPN for 123 renal masses completed by 7 urologists was performed.
  • We defined exophytic as more than 60%, mesophytic as 40% to 60%, and endophytic as less than 40% of the renal mass protruding off the surface of the kidney on radiologic imaging studies.
  • Hilar lesions were those located within 5 mm of the renal hilar structures, regardless of the surface characteristics.
  • RESULTS: The mean tumor size was 2.6 cm (range 1 to 9).
  • On final histopathologic examination, 3 patients (2.5%) had positive tumor resection margins.
  • Histopathologic examination of the renal masses revealed malignant pathologic features in 86 (69%) and benign findings in 37 (31%).
  • In our series, only 55% of exophytic tumors were malignant and, if malignant, were invariably low grade (96%).
  • CONCLUSIONS: The complications of LPN and the malignancy rate of the renal lesions were related to the tumor location within the kidney.
  • [MeSH-major] Kidney Neoplasms / pathology. Kidney Neoplasms / surgery. Laparoscopy. Nephrectomy / methods

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  • (PMID = 16765174.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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20. Val-Bernal JF, Aguilera C, Villagrá NT, Correas MA: Myxoma of the renal capsule. Pathol Res Pract; 2005;200(11-12):835-40
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  • [Title] Myxoma of the renal capsule.
  • Myxomas are uncommon soft-tissue neoplasms, which are extremely rare in the kidney, with only five cases documented in the intraparenchymal location.
  • However, renal capsular myxoma has not yet been reported.
  • We describe a unique case of a clinically detected renal myxoma arising in the capsule.
  • A radiological examination incidentally discovered a right renal tumor.
  • The resected kidney contained a well-circumscribed gelatinous capsular tumor.
  • The tumor cells showed diffuse immunoreactivity for vimentin.
  • No basal lamina was identified around the tumor cells.
  • The differential diagnosis includes many other benign and malignant soft-tissue lesions exhibiting prominent secondary myxoid features.
  • It is important to consider a renal capsular myxoma when examining lesions at this anatomic site to avoid misdiagnoses and to ensure that the patient receives appropriate treatment and prognostic information.
  • [MeSH-major] Kidney Neoplasms / pathology. Myxoma / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / analysis. Cell Nucleus / ultrastructure. Cytoplasmic Structures / ultrastructure. Humans. Immunoenzyme Techniques. Male. Nephrectomy. Treatment Outcome. Vimentin / analysis

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  • (PMID = 15792129.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Vimentin
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21. Sukov WR, Cheville JC, Lager DJ, Lewin JR, Sebo TJ, Lewin M: Malignant mixed epithelial and stromal tumor of the kidney with rhabdoid features: report of a case including immunohistochemical, molecular genetic studies and comparison to morphologically similar renal tumors. Hum Pathol; 2007 Sep;38(9):1432-7
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  • [Title] Malignant mixed epithelial and stromal tumor of the kidney with rhabdoid features: report of a case including immunohistochemical, molecular genetic studies and comparison to morphologically similar renal tumors.
  • Mixed epithelial stromal tumor of the kidney (MEST)/adult cystic nephroma (CN) is a lesion characterized by epithelial lined tubular or cystic structures interspersed within a variably prominent, distinctive spindle-cell stroma.
  • Although typically benign, cases with malignant features have been reported.
  • Herein, we report a MEST/CN with malignant stromal features and rhabdoid differentiation arising in the left kidney of an 84-year-old woman.
  • Histologically, the tumor displayed multiple tubules and variably sized cystic structures lined by benign epithelium with an intervening malignant-appearing spindle-cell stroma.
  • To our knowledge, this represents the first report in the literature of malignant MEST with rhabdoid features and suggests that this entity should be considered in the diagnosis of renal stromal malignancies with prominent rhabdoid features.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma / pathology. Kidney Neoplasms / pathology. Rhabdoid Tumor / pathology. Stromal Cells / pathology

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  • (PMID = 17707262.001).
  • [ISSN] 0046-8177
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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22. Tabibi A, Parvin M, Abdi H, Bashtar R, Zamani N, Abadpour B: Correlation between size of renal cell carcinoma and its grade, stage, and histological subtype. Urol J; 2007;4(1):10-3
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  • [Title] Correlation between size of renal cell carcinoma and its grade, stage, and histological subtype.
  • INTRODUCTION: The aim of this study was to determine the correlation between histological subtype, size, grade, and stage of the kidney tumors and to investigate whether a correlation exists between the size of the kidney tumor and its behavior.
  • MATERIALS AND METHODS: Between 1996 and 2004, we had 212 patients with radical or partial nephrectomy due to a kidney tumor at Shaheed Labbafinejad Medical Center.
  • Their pathologic blocks were re-evaluated with consideration of their tumor size and pathologic features.
  • RESULTS: Of 212 pathologic blocks, 17 (8%) were benign and 195 (92%) were malignant masses including 179 renal cell carcinoma (RCC) tumors.
  • Malignant tumors were slightly greater compared with the benign ones (P=.10).
  • There was no significant relation between the size of tumor and the histological subtype.
  • Significant relations between the size of the kidney tumor and the nuclear grade (P=.007), clinical symptoms (P=.02), and extracapsular extension (P<.001) were observed.
  • In smaller RCC tumors (< 4 cm), extracapsular extension (stages T3 and T4) was rare (1 in 29).
  • However, smaller RCC tumors were not significantly different from those larger than 4 cm regarding the nuclear grade, symptoms, and histological subtypes.
  • CONCLUSION: Tumor size is not an independent predictor for the histological subtype of the tumors; however, larger malignant tumors may have higher grades, higher stages, and clinical symptoms.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Tumor Burden
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Carcinoma, Transitional Cell / pathology. Carcinoma, Transitional Cell / surgery. Child. Child, Preschool. Female. Humans. Male. Middle Aged. Neoplasm Staging. Nephrectomy. Sarcoma / pathology. Sarcoma / surgery. Wilms Tumor / pathology. Wilms Tumor / surgery

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  • (PMID = 17514604.001).
  • [ISSN] 1735-1308
  • [Journal-full-title] Urology journal
  • [ISO-abbreviation] Urol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Iran
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23. Yu ZX, Xia GP, Hu WH, Chen W, Li XB, Chen HD, Lin LZ, Deng ZX, Cai B, Weng ZL: [Etiology, diagnosis and management of spontaneous per renal hemorrhage]. Zhonghua Yi Xue Za Zhi; 2006 Jan 3;86(1):39-41
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  • [Title] [Etiology, diagnosis and management of spontaneous per renal hemorrhage].
  • OBJECTIVE: To investigate the etiology, diagnosis, and management of spontaneous perirenal hemorrhage (SPH).
  • METHODS: The clinical data of 35 patients, 10 males and 12 females, aged 35.9 (12-77), with the diagnosis of SPH, without history of trauma, anticoagulant use, dialysis, and renal transplantation, were analyzed.
  • RESULTS: The underlying disease of SPH included angiomyolipoma (18 cases), renal cell carcinoma (7 cases), kidney cyst (2 cases), renal artery aneurysm (3 cases), rupture of renal artery aneurysm accompanied with pregnancy (2 cases), renal pheochromocytoma (3 cases 2 of which accompanied with pregnancy), congenital stricture of pelvic ureter junction (1 case), and liver cancer (1 case).
  • The most common underlying diseases were nephrogenic (96%) with angiomyolipoma ranking first (54%) followed by renal cell carcinoma (21%).
  • CT helped in diagnosis of 34 cases.
  • CONCLUSION: The most common causes of SPH is renal neoplasms more than 50% of which are benign.
  • Renal artery aneurysm and pheochromocytoma tend to rupture during pregnancy.
  • CT is the first method of choice in diagnosis.
  • [MeSH-major] Hemorrhage / radiography. Hemorrhage / therapy. Kidney Diseases / radiography. Kidney Diseases / therapy
  • [MeSH-minor] Adolescent. Adult. Aged. Aneurysm / complications. Angiography, Digital Subtraction. Angiomyolipoma / complications. Anticoagulants / therapeutic use. Child. Female. Humans. Kidney Neoplasms / complications. Kidney Transplantation. Male. Middle Aged. Pregnancy. Renal Artery / pathology. Renal Dialysis. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16606534.001).
  • [ISSN] 0376-2491
  • [Journal-full-title] Zhonghua yi xue za zhi
  • [ISO-abbreviation] Zhonghua Yi Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Anticoagulants
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24. Yang Y, Nie X, Lu J, Lu XY, Wei YY, Wang H, Han ZH, Chen ZH, Zheng J: [Mixed epithelial and stromal tumor of kidney]. Zhonghua Bing Li Xue Za Zhi; 2006 Jan;35(1):29-31
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  • [Title] [Mixed epithelial and stromal tumor of kidney].
  • OBJECTIVE: To study the clinicopathological features and differential diagnoses of mixed epithelial and stromal tumor of the kidney.
  • METHODS: Clinical and pathological characteristics of 4 cases of mixed epithelial and stromal tumor of the kidney were studied.
  • Radiologic studies revealed cystic and solid masses involving the kidney.
  • Grossly the tumors had a solid and cyst appearance.
  • Microscopically, the tumors were composed of a mixture of stromal and epithelial elements.
  • Stromal elements essentially consisted of spindle cells, with thick-walled blood vessels and bands of smooth muscle cells as distinctive features of the tumor.
  • CONCLUSIONS: Mixed epithelial and stromal tumor of the kidney is a benign neoplasm with distinct histopathological features.
  • It should be distinguished from many other renal neoplasms.
  • [MeSH-major] Kidney Neoplasms / pathology. Neoplasms, Complex and Mixed / pathology. Neoplasms, Glandular and Epithelial / pathology
  • [MeSH-minor] Actins / metabolism. Adult. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Male. Middle Aged. Muscle, Smooth / metabolism. Nephrectomy / methods. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16608646.001).
  • [ISSN] 0529-5807
  • [Journal-full-title] Zhonghua bing li xue za zhi = Chinese journal of pathology
  • [ISO-abbreviation] Zhonghua Bing Li Xue Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
  • [Chemical-registry-number] 0 / Actins; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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25. Jin H, Xu ZY, Yu WY, Wang ES, Zhang BR: [Diagnosis and surgical management of primary cardiac neoplasms]. Zhonghua Zhong Liu Za Zhi; 2006 Aug;28(8):609-11
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  • [Title] [Diagnosis and surgical management of primary cardiac neoplasms].
  • OBJECTIVE: To review and summarize the experience in diagnosis and surgical management of primary cardiac neoplasms.
  • METHODS: 112 patients with primary cardiac neoplasms were treated surgically from Jan.
  • Those tumors were grouped into three categories: myxomas (98), benign nonmyxomas (3), and malignant tumors (11).
  • Five of 11 malignant tumor patients underwent biopsy or palliative operation, the other patients received complete excision.
  • All patients' diagnosis was confirmed by echocardiography.
  • One patient developed and died of progressive hepatic and renal function failure postoperatively.
  • The follow-up results of benign nonmyxomas were similar to those of myxomas.
  • Mean follow-up of all survived malignant tumor patient was 6 months (range, 2 months to 12 months).
  • CONCLUSION: Surgical resection, whenever possible, is the first treatment choice for all kinds of primary cardiac tumors.
  • Surgical resection of myxoma and benign nonmyxoma can give excellent long-term results which may lead to eventual cure of myxoma and benign nonmyxoma.
  • For malignant tumor patient, surgical treatment is only palliative and to prolong the life of patients.
  • [MeSH-major] Cardiac Surgical Procedures / methods. Heart Neoplasms / diagnosis. Heart Neoplasms / surgery. Myxoma / diagnosis. Myxoma / surgery
  • [MeSH-minor] Adult. Aged. Echocardiography. Female. Follow-Up Studies. Humans. Male. Middle Aged. Neoplasm Recurrence, Local. Palliative Care. Retrospective Studies. Survival Rate. Tricuspid Valve / surgery

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  • (PMID = 17236557.001).
  • [ISSN] 0253-3766
  • [Journal-full-title] Zhonghua zhong liu za zhi [Chinese journal of oncology]
  • [ISO-abbreviation] Zhonghua Zhong Liu Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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26. Mabrut JY, Fernandez-Cruz L, Azagra JS, Bassi C, Delvaux G, Weerts J, Fabre JM, Boulez J, Baulieux J, Peix JL, Gigot JF, Hepatobiliary and Pancreatic Section (HBPS) of the Royal Belgian Society of Surgery, Belgian Group for Endoscopic Surgery (BGES), Club Coelio: Laparoscopic pancreatic resection: results of a multicenter European study of 127 patients. Surgery; 2005 Jun;137(6):597-605
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  • Detailed questionnaires were used, focusing on patients, tumors, operative data, and late outcome.
  • RESULTS: During the study period, 127 patients with presumed pancreatic neoplasms were enrolled in this series.
  • Final diagnoses included benign pancreatic diseases in 111 patients (87%; insulinoma: 22, neuroendocrine neoplasm: 20, mucinous cystadenoma: 26, serous cystadenoma: 21, chronic pancreatitis: 11, others: 11), and 16 patients (13%) had malignant pancreatic diseases (insulinoma: 3, neuroendocrine neoplasm: 5, ductal adenocarcinoma: 4, cystadenocarcinoma: 2, renal metastases: 2).
  • Five patients with presumed benign pancreatic disease had malignancy at final pathology.
  • The median tumor size was 30 mm (range, 5-120 mm); 89% of tumors were located in the left pancreas.
  • During a median follow-up of 15 months (range, 3-47 months), 23% of the patients with pancreatic malignancies had tumor recurrence.
  • Late outcome was satisfactory in all patients with benign diseases.
  • CONCLUSIONS: LPR is feasible and safe in selected patients with presumed benign and distal pancreatic tumors.
  • [MeSH-major] Laparoscopy. Pancreatectomy. Pancreatic Neoplasms / surgery
  • [MeSH-minor] Follow-Up Studies. Humans. Length of Stay. Neoplasm Recurrence, Local. Reoperation. Retrospective Studies. Treatment Outcome

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  • (PMID = 15962401.001).
  • [ISSN] 0039-6060
  • [Journal-full-title] Surgery
  • [ISO-abbreviation] Surgery
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] United States
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27. Koo HJ, Lee DH, Kim IY: Renal hilar control during laparoscopic partial nephrectomy: to clamp or not to clamp. J Endourol; 2010 Aug;24(8):1283-7
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  • [Title] Renal hilar control during laparoscopic partial nephrectomy: to clamp or not to clamp.
  • BACKGROUND AND PURPOSE: To decrease intraoperative and perioperative morbidity that is associated with laparoscopic partial nephrectomy (LPN), clamping of the renal hilum has been advocated.
  • It has been suggested, however, that renal hilar control is not necessary in all patients.
  • We compared the perioperative and pathologic results of 21 consecutive patients who underwent LPN with or without renal hilar clamping at our institution.
  • Renal hilar control was deemed necessary if the depth of tumor invasion was greater than 50% of the renal parenchyma on CT or MRI.
  • RESULTS: The mean tumor size was 2.6 cm (range 0.8-4.2 cm) in the nonclamped group and 2.3 cm (range 1.5-3 cm) in the clamped group.
  • In the nonclamped group, 7 of the 11 procedures were for benign tumors while only 2 of the 10 lesions in the clamped group were benign.
  • Tumors that need cross-clamping of the renal hilum were more likely to be malignant.

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  • (PMID = 20629571.001).
  • [ISSN] 1557-900X
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Al-Marhoon MS: Small Incidental Renal Masses in Adults: Review of the literature. Sultan Qaboos Univ Med J; 2010 Aug;10(2):196-202
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  • [Title] Small Incidental Renal Masses in Adults: Review of the literature.
  • Incidental renal tumours are becoming an important clinical problem that many physicians will need to deal with.
  • A good knowledge of the nature of these tumours and how to manage them is therefore needed.
  • The aim of this paper is to review the literature about incidental renal tumours in adults.
  • Many incidentally discovered small renal tumours (<4 cm) are benign and of low stage, grade and progression potential.
  • Tumour renal biopsy is encouraged prior to needle-ablative therapy and surveillance.
  • Awareness about incidental renal masses and their management is essential for treating doctors.

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  • [Cites] JAMA. 1999 May 5;281(17):1628-31 [10235157.001]
  • [Cites] J Urol. 1990 Oct;144(4):852-7; discussion 857-8 [2398558.001]
  • [Cites] Urology. 2000 Aug 1;56(2):190-6 [10925076.001]
  • [Cites] Urology. 2000 Sep 1;56(3):387-92 [10962300.001]
  • [Cites] Am J Surg Pathol. 2002 Mar;26(3):281-91 [11859199.001]
  • [Cites] Eur J Cancer Prev. 2002 Apr;11(2):171-8 [11984136.001]
  • [Cites] Am J Surg Pathol. 2003 May;27(5):612-24 [12717246.001]
  • [Cites] J Urol. 2003 Dec;170(6 Pt 1):2217-20 [14634382.001]
  • [Cites] Cancer. 2004 Feb 15;100(4):738-45 [14770429.001]
  • [Cites] Radiology. 2006 Jul;240(1):6-22 [16709793.001]
  • [Cites] J Urol. 2006 Sep;176(3):896-9 [16890647.001]
  • [Cites] CA Cancer J Clin. 2007 Jan-Feb;57(1):43-66 [17237035.001]
  • [Cites] J Urol. 2007 Mar;177(3):849-53; discussion 853-4 [17296355.001]
  • [Cites] J Endourol. 2007 Aug;21(8):819-23 [17867935.001]
  • [Cites] Eur Urol. 2008 May;53(5):1003-11 [18061339.001]
  • [Cites] Urology. 1998 Feb;51(2):203-5 [9495698.001]
  • [Cites] Am Fam Physician. 2001 Jan 15;63(2):288-94, 299 [11201694.001]
  • [Cites] Urology. 2002 Dec;60(6):1003-9 [12475658.001]
  • [Cites] AJR Am J Roentgenol. 2003 May;180(5):1281-7 [12704038.001]
  • [Cites] Urol Clin North Am. 2003 Aug;30(3):499-514 [12953751.001]
  • [Cites] Urology. 2003 Nov;62(5):827-30 [14624902.001]
  • [Cites] Eur Urol. 2006 Feb;49(2):401-5 [16387417.001]
  • [Cites] J Urol. 2006 Feb;175(2):425-31 [16406965.001]
  • [Cites] J Urol. 2007 Feb;177(2):466-70; discussion 470 [17222611.001]
  • [Cites] J Urol. 2007 Aug;178(2):414-7; discussion 416-7 [17561161.001]
  • [Cites] J Urol. 2007 Aug;178(2):379-86 [17561170.001]
  • [Cites] J Urol. 2008 Apr;179(4):1277-81; discussion 1281-3 [18280507.001]
  • [Cites] J Urol. 2008 Oct;180(4):1257-61; discussion 1261 [18707712.001]
  • [Cites] Eur Urol. 1990;18 Suppl 2:2-3 [2226598.001]
  • [Cites] Urology. 2000 Jul;56(1):58-62 [10869624.001]
  • (PMID = 21509229.001).
  • [ISSN] 2075-0528
  • [Journal-full-title] Sultan Qaboos University medical journal
  • [ISO-abbreviation] Sultan Qaboos Univ Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Oman
  • [Other-IDs] NLM/ PMC3074712
  • [Keywords] NOTNLM ; Incidental / Renal cell carcinoma / Tumors / renal
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29. Azabdaftari G, Alroy J, Banner BF, Ucci A, Bhan I, Cheville JC: S100 protein expression distinguishes metanephric adenomas from other renal neoplasms. Pathol Res Pract; 2008;204(10):719-23
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  • [Title] S100 protein expression distinguishes metanephric adenomas from other renal neoplasms.
  • Metanephric adenoma is a benign renal neoplasm with morphologic features similar to those of malignant renal neoplasms, such as papillary renal cell carcinoma (RCC) and Wilms' tumor.
  • Different methods have been used to distinguish between metanephric adenoma and papillary RCC and Wilms' tumor.
  • In the current study, we compared the expression of S100 protein in 15 cases of metanephric adenoma, 10 cases of Wilms' tumor, and 13 cases of papillary RCC.
  • Our results revealed strong expression of S100 proteins in all cases of metanephric adenoma, weak expression in two cases of Wilms' tumor, and no expression in any of the cases of papillary RCC.
  • These findings indicate that S100 could be a useful and accessible tool for the diagnosis of metanephric adenoma.
  • [MeSH-major] Adenoma / chemistry. Carcinoma, Renal Cell / chemistry. Kidney Neoplasms / chemistry. S100 Proteins / analysis. Wilms Tumor / chemistry

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  • (PMID = 18621486.001).
  • [ISSN] 0344-0338
  • [Journal-full-title] Pathology, research and practice
  • [ISO-abbreviation] Pathol. Res. Pract.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Germany
  • [Chemical-registry-number] 0 / S100 Proteins
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30. Yu G, Goodloe S Jr, D'Angelis CA, McGrath BE, Chen F: Giant clear cell hidradenoma of the knee. J Cutan Pathol; 2010 Sep;37(9):e37-41
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  • Hidradenomas, also referred to as nodular hidradenomas or clear cell hidradenomas (CCH), are benign cutaneous eccrine tumors usually 2-3 cm in dimension.
  • The tumor was mobile, located above the patellar tendon and was without bony involvement on imaging studies.
  • Grossly, the resected tumor was unencapsulated and tan, with a solid and cystic cut surface showing papillary excrescences on the cyst wall.
  • Microscopically, the tumor cells showed an infiltrative growth pattern at the periphery, however, the tumor cytology was bland and no necrosis or mitoses were identified.
  • Immunohistochemically, tumor cells were positive for cytokeratin, CAM5.2, p53, carcino-embryonic antigen (CEA) and epithelial membrane antigen (EMA), and negative for CD10 and Ki-67.
  • The cytological features of hidradenomas can present diagnostic challenges, as other 'clear cell' tumors such as metastatic renal cell carcinoma should be considered.
  • [MeSH-major] Acrospiroma / pathology. Sweat Gland Neoplasms / pathology
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Carcinoma, Renal Cell / diagnosis. Carcinoma, Renal Cell / secondary. Diagnosis, Differential. Humans. Immunohistochemistry. Kidney Neoplasms / diagnosis. Knee. Magnetic Resonance Imaging. Male. Treatment Outcome

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  • (PMID = 19615032.001).
  • [ISSN] 1600-0560
  • [Journal-full-title] Journal of cutaneous pathology
  • [ISO-abbreviation] J. Cutan. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Denmark
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
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31. Parikh P, Chan TY, Epstein JI, Argani P: Incidental stromal-predominant mixed epithelial-stromal tumors of the kidney: a mimic of intraparenchymal renal leiomyoma. Arch Pathol Lab Med; 2005 Jul;129(7):910-4
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  • [Title] Incidental stromal-predominant mixed epithelial-stromal tumors of the kidney: a mimic of intraparenchymal renal leiomyoma.
  • CONTEXT: Mixed epithelial-stromal tumor of the kidney is a recently recognized benign renal tumor that usually occurs in adult women and typically forms a sizable lesion with solid and cystic areas.
  • OBJECTIVE: To review the clinicopathologic features of 3 small mixed epithelial-stromal tumors of the kidney that were incidental findings in kidneys removed for other reasons.
  • CONCLUSIONS: Mixed epithelial-stromal tumor of the kidney may present as an incidental stromal-predominant lesion within the kidney.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis. Leiomyoma / diagnosis. Neoplasms, Complex and Mixed / diagnosis. Neoplasms, Glandular and Epithelial / diagnosis. Smooth Muscle Tumor / diagnosis. Stromal Cells / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Female. Humans. Middle Aged

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  • (PMID = 15974815.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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32. Murphy AM, Buck AM, Benson MC, McKiernan JM: Increasing detection rate of benign renal tumors: evaluation of factors predicting for benign tumor histologic features during past two decades. Urology; 2009 Jun;73(6):1293-7
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  • [Title] Increasing detection rate of benign renal tumors: evaluation of factors predicting for benign tumor histologic features during past two decades.
  • OBJECTIVES: To determine whether the detection of benign renal tumors is increasing and to identity the predictors of benign histologic features.
  • The detection of renal cortical tumors has increased with the increased use of abdominal imaging.
  • Current imaging and biopsy techniques cannot predict the renal tumor histologic features with complete accuracy, and many patients undergo surgery for benign lesions.
  • A cohort of 775 patients with a tumor diameter of <or.0 cm, nonmetastatic disease, and nonfamilial disease was selected.
  • Univariate and multivariate logarithmic regression analyses were used to determine the parameters to predict for benign histologic features.
  • RESULTS: The proportion of renal surgery for benign tumors of <or.0 cm in diameter has increased annually.
  • When patients were stratified by the year of surgery, the proportion of benign tumors was 5.0% before 1998, 15.2% from 1998 to 2003, and 21.2% from 2004 to 2007.
  • The mean diameter of benign and malignant tumors was 3.0 and 3.5 cm, respectively, and the mean tumor diameter significantly decreased during the study period (P = .006).
  • Using multivariate analysis, the year of surgery, tumor diameter, and female sex were independent predictors of benign histologic features (P < .05).
  • Age, incidental diagnosis, body mass index, and race were not significant predictors (P > .05).
  • CONCLUSIONS: Even when controlling for tumor diameter and sex, the incidence of benign tumors detected at renal surgery at our institution has increased significantly in the past 2 decades.
  • [MeSH-major] Kidney Neoplasms / pathology
  • [MeSH-minor] Aged. Diagnostic Techniques, Urological / statistics & numerical data. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Time Factors

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  • [CommentIn] Urology. 2009 Jun;73(6):1297-8 [19482148.001]
  • [CommentIn] Urology. 2009 Jun;73(6):1298-9 [19482149.001]
  • (PMID = 19371933.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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33. Derchi LE, Grenier N, Heinz-Peer G, Dogra V, Franco F, Rollandi GA, Deminiere C: Imaging of renal leiomyomas. Acta Radiol; 2008 Sep;49(7):833-8
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  • [Title] Imaging of renal leiomyomas.
  • BACKGROUND: Renal leiomyomas are rare benign tumors of the kidney which can be found at autopsy as small capsular nodules in about 5% of cases.
  • PURPOSE: To describe the imaging characteristics observed in a series of eight patients with pathology-proven asymptomatic leiomyomas of the kidney.
  • MATERIAL AND METHODS: We reviewed the imaging findings observed in eight patients with pathologically proven asymptomatic renal leiomyomas discovered during studies performed for reasons unrelated to the kidney.
  • Six were at the periphery of the kidney, compressed its outer surface, but did not cause disruption of the cortex; two involved the renal cortex.
  • A cleavage plane between the tumor and the kidney was revealed at CT and/or ultrasonography in three of the cases located at the periphery.
  • At CT, they were slightly hyperdense before contrast medium injection; all were hypodense to the renal cortex after contrast medium.
  • CONCLUSION: There are some imaging findings that can help to suggest the diagnosis of renal leiomyomas.
  • First, their density: all tumors examined before contrast were hyperdense to the kidney, with density similar to that of muscles, and all had lower enhancement than the adjacent renal parenchyma.
  • Second, the location and margins of the tumors: most were peripheral, without involvement of the renal cortex and with well-defined margins.
  • Although not pathognomonic for a renal leiomyoma, the combination of these findings should include leiomyoma in the list of differential diagnoses.
  • [MeSH-major] Diagnostic Imaging. Kidney Neoplasms / diagnosis. Leiomyoma / diagnosis
  • [MeSH-minor] Adult. Aged. Contrast Media. Diagnosis, Differential. Female. Humans. Male. Middle Aged

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  • (PMID = 19143066.001).
  • [ISSN] 1600-0455
  • [Journal-full-title] Acta radiologica (Stockholm, Sweden : 1987)
  • [ISO-abbreviation] Acta Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Contrast Media
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34. Prasad SR, Surabhi VR, Menias CO, Raut AA, Chintapalli KN: Benign renal neoplasms in adults: cross-sectional imaging findings. AJR Am J Roentgenol; 2008 Jan;190(1):158-64
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  • [Title] Benign renal neoplasms in adults: cross-sectional imaging findings.
  • OBJECTIVE: A broad spectrum of benign renal neoplasms in adults shows characteristic ontogeny, histology, and tumor biology.
  • Benign renal tumors are classified into renal cell tumors, metanephric tumors, mesenchymal tumors, and mixed epithelial and mesenchymal tumors.
  • Select benign tumors show characteristic anatomic distribution and imaging features.
  • However, because of overlapping of findings between benign and malignant renal tumors, histologic evaluation may be required to establish a definitive diagnosis.
  • CONCLUSION: We attempt to provide a comprehensive, contemporary review of benign renal neoplasms that occur in adults, focusing on cross-sectional imaging characteristics.
  • [MeSH-major] Kidney Neoplasms / diagnosis
  • [MeSH-minor] Adenofibroma / diagnosis. Adenoma / diagnosis. Adenoma, Oxyphilic / diagnosis. Adult. Aged. Angiomyolipoma / diagnosis. Carcinoma, Renal Cell / diagnosis. Cross-Sectional Studies. Diagnosis, Differential. Female. Hemangioma / diagnosis. Humans. Leiomyoma / diagnosis. Magnetic Resonance Imaging. Male. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 18094306.001).
  • [ISSN] 1546-3141
  • [Journal-full-title] AJR. American journal of roentgenology
  • [ISO-abbreviation] AJR Am J Roentgenol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 62
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35. Jiang W, Fujii H, Matsumoto T, Ohtsuji N, Tsurumaru M, Hino O: Birt-Hogg-Dubé (BHD) gene mutations in human gastric cancer with high frequency microsatellite instability. Cancer Lett; 2007 Apr 8;248(1):103-11
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  • Birt-Hogg-Dubé (BHD) syndrome is a rare inherited genodermatosis characterized by benign hamartomatous skin lesions and an increased risk of pneumothorax and renal tumors.
  • This mutational hot spot is also reported to be a target of mutation in microsatellite instability (MSI) sporadic colorectal tumors.
  • [MeSH-major] Microsatellite Instability. Mutation. Proteins / genetics. Proto-Oncogene Proteins / genetics. Stomach Neoplasms / pathology. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Base Sequence. DNA Mutational Analysis. Exons / genetics. Female. Gene Frequency. Humans. Male. Middle Aged. Neoplasm Staging. Poly C / genetics. Protein-Serine-Threonine Kinases. Receptors, Transforming Growth Factor beta / genetics. bcl-2-Associated X Protein / genetics

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  • (PMID = 16870330.001).
  • [ISSN] 0304-3835
  • [Journal-full-title] Cancer letters
  • [ISO-abbreviation] Cancer Lett.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Chemical-registry-number] 0 / BAX protein, human; 0 / FLCN protein, human; 0 / Proteins; 0 / Proto-Oncogene Proteins; 0 / Receptors, Transforming Growth Factor beta; 0 / Tumor Suppressor Proteins; 0 / bcl-2-Associated X Protein; 30811-80-4 / Poly C; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.30 / transforming growth factor-beta type II receptor
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36. Lane BR, Tiong HY, Campbell SC, Fergany AF, Weight CJ, Larson BT, Novick AC, Flechner SM: Management of the adrenal gland during partial nephrectomy. J Urol; 2009 Jun;181(6):2430-6; discussion 2436-7
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  • The indications for adrenalectomy in patients undergoing partial nephrectomy are not clearly defined and some surgeons perform it routinely for large and/or upper pole renal tumors.
  • Pathological analysis revealed direct invasion of the adrenal gland by renal cell carcinoma (1), renal cell carcinoma metastasis (2), other adrenal neoplasms (3) or benign tissue (42, 87%).
  • Metachronous adrenalectomy was ipsilateral (10), contralateral (2) or bilateral (3), revealing metastatic renal cell carcinoma in 11 patients.
  • CONCLUSIONS: Adrenalectomy should not be routinely performed during partial nephrectomy, even for upper pole tumors.
  • [MeSH-major] Adrenal Gland Neoplasms / surgery. Adrenalectomy. Carcinoma, Renal Cell / surgery. Kidney Neoplasms / surgery. Nephrectomy / methods
  • [MeSH-minor] Adrenal Glands. Aged. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness

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  • (PMID = 19371896.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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37. Donovan DJ, Freeman JH: Solitary intramedullary spinal cord tumor presenting as the initial manifestation of metastatic renal cell carcinoma: case report. Spine (Phila Pa 1976); 2006 Jun 15;31(14):E460-3
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  • [Title] Solitary intramedullary spinal cord tumor presenting as the initial manifestation of metastatic renal cell carcinoma: case report.
  • STUDY DESIGN: We present the case of a patient with a solitary neoplasm of the intramedullary spinal cord.
  • OBJECTIVE: The tumor caused findings of Brown-Séquard syndrome and was the initial presentation of widely metastatic renal cell carcinoma (RCC).
  • METHODS: The tumor was resected, and the patient's neurologic deficits slowly improved.
  • The histopathology suggested an epithelioid neoplasm.
  • However, despite expert review, the diagnosis was nonspecific, and the tumor appeared benign.
  • RESULTS: It soon recurred in the spinal cord, and repeat imaging studies showed numerous new metastases and a primary renal neoplasm.
  • Biopsy and a repeat histopathologic analysis confirmed RCC, and the patient died of disseminated disease within another 2 months.
  • CONCLUSIONS: Despite being uncommon, spinal cord metastases should be considered in some patients before surgery because it may expedite diagnosis, mitigate the need for surgery, and improve the quality of life for these patients.
  • Clinical factors suggesting metastasis include a personal or family history of malignancy or conditions predisposing to it, the presence of multiple tumors in the spinal cord or elsewhere, nonspecific constitutional symptoms, such as weight loss or decreased appetite, and, specifically for RCC, an abnormally increased hematocrit.
  • [MeSH-major] Brown-Sequard Syndrome / etiology. Carcinoma, Renal Cell / secondary. Kidney Neoplasms / pathology. Spinal Cord Neoplasms / complications. Spinal Cord Neoplasms / secondary

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  • (PMID = 16778676.001).
  • [ISSN] 1528-1159
  • [Journal-full-title] Spine
  • [ISO-abbreviation] Spine
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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38. Halazun KJ, Al-Mukhtar A, Aldouri A, Malik HZ, Attia MS, Prasad KR, Toogood GJ, Lodge JP: Right hepatic trisectionectomy for hepatobiliary diseases: results and an appraisal of its current role. Ann Surg; 2007 Dec;246(6):1065-74
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  • RESULTS: Of the 275 patients, 160 had colorectal metastases, 49 had biliary tract cancers, 20 had hepatocellular carcinomas, 20 had other metastatic tumors, and 12 had benign diseases.
  • Concomitant procedures were carried out in 192 patients: caudate lobectomy in 45 patients, resection of tumors from the liver remnant in 57 patients, resection of the extrahepatic biliary tree in 45 patients, and lymphadenectomy in 45 patients.
  • Survivals for individual tumor types were acceptable, with 5-year survivals for colorectal metastasis and cholangiocarcinoma being 38% and 32%, respectively.
  • Age over 70 years, preoperative bilirubin levels, and the development of postoperative renal failure were found to be independent predictors of long-term survival.
  • The outcome is not influenced by additional concomitant resection of tumors from the planned liver remnant.
  • [MeSH-major] Hepatectomy / methods. Liver Neoplasms / surgery

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  • [CommentIn] Ann Surg. 2008 Jul;248(1):138-9; author reply 139-40 [18580219.001]
  • (PMID = 18043112.001).
  • [ISSN] 0003-4932
  • [Journal-full-title] Annals of surgery
  • [ISO-abbreviation] Ann. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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39. Zhai QJ, Ozcan A, Hamilton C, Shen SS, Coffey D, Krishnan B, Truong LD: PAX-2 expression in non-neoplastic, primary neoplastic, and metastatic neoplastic tissue: A comprehensive immunohistochemical study. Appl Immunohistochem Mol Morphol; 2010 Jul;18(4):323-32
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  • PAX-2 is a transcription factor that controls the development of the kidney, organs deriving from the mesonephric (Wolffian) duct, and those related to the Müllerian duct.
  • Although PAX-2 is shown to be a sensitive marker for tumors derived from these organs, but whether it is specific, that is, whether other tumor types also express PAX-2, has not been systematically evaluated in either primary or metastatic tumors.
  • Tissue sections from 937 normal or reactive tissue samples, 759 primary neoplasms, and 332 metastatic neoplasms were submitted to PAX-2 immunostain.
  • Among the non-neoplastic tissue, PAX-2 was expressed in glomerular parietal epithelial cells, renal collecting duct cells, atrophic renal tubular cells, epithelial cells of ovarian surface, fallopian tube, endocervix, endometrium, seminal vesicle, and lymphocytes.
  • Among the primary neoplasms, PAX-2 was noted in 104/122 (85%) of renal cell carcinoma, 31/95 carcinomas of Müllerian origin, 17/17 (100%) lymphomas, 4/4 (100%) nephrogenic adenomas, and 1/16 (6%) benign parathyroid tumors, but was negative in 477 other tumors.
  • Among the metastatic tumors, PAX-2 was noted in 70/95 (74%) metastatic renal cell carcinomas, 14/20 (70%) metastatic tumors of Müllerian origin, 1/20 (5%) metastatic colon carcinoma of lymph nodes, 1/62 (2%) metastatic breast carcinoma of lymph nodes, but was not seen in the remaining 247 metastatic tumors.
  • PAX-2 is a sensitive and specific marker for tumors of renal or Müllerian origin in both primary and metastatic contexts.

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  • (PMID = 20216401.001).
  • [ISSN] 1533-4058
  • [Journal-full-title] Applied immunohistochemistry & molecular morphology : AIMM
  • [ISO-abbreviation] Appl. Immunohistochem. Mol. Morphol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / PAX2 Transcription Factor
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40. Castillo OA, Vitagliano G, Cortes O, Kerkebe M, Pinto I, Arellano L: Bilateral laparoscopic adrenalectomy. J Endourol; 2007 Sep;21(9):1053-8
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  • Bilateral adrenalectomy is indicated in patients with Cushing's disease secondary to macroadenoma or hypophysial hyperplasia in whom medical treatment and transsphenoid surgery have failed.
  • Also, it is the first choice for bilateral benign tumors and metastatic neoplasia.
  • There were 6 cases of bilateral pheochromocytoma, 6 patients with Cushing's disease, 3 cases of metastasis, 3 congenital adrenal hyperplasias, 2 hyperaldosteronisms, and a single case each of adrenal adenoma and myelolipoma.
  • The mean tumor size was 4.15 cm (range 1-11 cm).
  • There was only one intraoperative complication (2.2%), a renal-vein injury that was controlled with intracorporeal suturing.

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  • (PMID = 17941786.001).
  • [ISSN] 0892-7790
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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41. McHugh JB, Hoschar AP, Dvorakova M, Parwani AV, Barnes EL, Seethala RR: p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma. Head Neck Pathol; 2007 Dec;1(2):123-31
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  • [Title] p63 immunohistochemistry differentiates salivary gland oncocytoma and oncocytic carcinoma from metastatic renal cell carcinoma.
  • Metastatic renal cell carcinoma (RCC) can pose diagnostic challenges in the head and neck often resembling benign and malignant oncocytic lesions.
  • Tumors were stained with antibodies to p63, renal cell carcinoma marker (RCCm), CD10, and vimentin.
  • Eight benign oncocytic tumors (29%) had clear cell features while 6 metastatic RCC (37%) had oncocytic features.
  • Mitotic rates were only significantly different between benign oncocytic tumors and metastatic RCC.
  • Seven benign oncocytic tumors (25%) and 5 oncocytic carcinomas (56%) had RCC-like vascular stroma.
  • All primary salivary gland tumors were positive for p63, predominately in basal cell-type distribution.
  • While clinical history and morphology usually are adequate, demonstration of p63 staining can definitively exclude metastatic RCC from the differential diagnosis of similar appearing tumors in salivary glands, namely oncocytoma and oncocytic carcinoma, with 100% specificity and sensitivity.
  • [MeSH-major] Adenocarcinoma, Clear Cell / diagnosis. Adenoma, Oxyphilic / diagnosis. Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Membrane Proteins / metabolism. Salivary Gland Neoplasms / diagnosis. Salivary Gland Neoplasms / metabolism
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans. Predictive Value of Tests

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  • [Cites] J Invest Dermatol. 1999 Dec;113(6):1099-105 [10594758.001]
  • [Cites] Otolaryngol Head Neck Surg. 2002 Jun;126(6):657-62 [12087334.001]
  • [Cites] Am J Surg Pathol. 2001 Aug;25(8):1054-60 [11474290.001]
  • [Cites] Adv Anat Pathol. 2002 Sep;9(5):280-9 [12195217.001]
  • [Cites] Laryngoscope. 2002 Sep;112(9):1598-602 [12352670.001]
  • [Cites] Virchows Arch. 2002 Nov;441(5):428-36 [12447671.001]
  • [Cites] J Histochem Cytochem. 2003 Feb;51(2):133-9 [12533521.001]
  • [Cites] J Histochem Cytochem. 2003 Aug;51(8):1097-9 [12871991.001]
  • [Cites] Lab Invest. 1970 Dec;23(6):567-80 [5530737.001]
  • [Cites] Mich Med. 1971 Jul;70(16):616-8 [5571989.001]
  • [Cites] Laryngoscope. 1973 Jun;83(6):898-905 [4711327.001]
  • [Cites] Laryngoscope. 1981 Apr;91(4):517-9 [6261053.001]
  • [Cites] South Med J. 1981 Sep;74(9):1050-2 [7280750.001]
  • [Cites] Pathol Res Pract. 1986 Dec;181(6):684-92 [3562340.001]
  • [Cites] Oral Surg Oral Med Oral Pathol. 1988 Jan;65(1):61-6 [3422397.001]
  • [Cites] Hum Pathol. 1988 Jul;19(7):862-7 [3402976.001]
  • [Cites] Head Neck. 1989 Mar-Apr;11(2):174-8 [2656583.001]
  • [Cites] Histopathology. 1990 May;16(5):487-93 [2361662.001]
  • [Cites] Am J Surg Pathol. 1991 Jun;15(6):514-28 [2031528.001]
  • [Cites] Pathol Annu. 1992;27 Pt 1:263-304 [1736246.001]
  • [Cites] Cancer. 1996 Dec 1;78(11):2281-7 [8940996.001]
  • [Cites] Semin Diagn Pathol. 1997 Aug;14(3):203-12 [9279976.001]
  • [Cites] J Oral Pathol Med. 1998 May;27(5):225-8 [9682986.001]
  • [Cites] Mol Cell. 1998 Sep;2(3):305-16 [9774969.001]
  • [Cites] Am J Surg Pathol. 2007 Jan;31(1):44-57 [17197918.001]
  • [Cites] Nature. 1999 Apr 22;398(6729):714-8 [10227294.001]
  • [Cites] Laryngoscope. 2005 Jun;115(6):1097-100 [15933529.001]
  • [Cites] Head Neck. 2005 Aug;27(8):696-702 [16021638.001]
  • [Cites] Otolaryngol Head Neck Surg. 2000 Mar;122(3):464 [10699832.001]
  • [Cites] Am J Clin Pathol. 2001 Dec;116(6):823-30 [11764070.001]
  • [Cites] Trends Genet. 2002 Feb;18(2):90-5 [11818141.001]
  • [Cites] Clin Cancer Res. 2002 Feb;8(2):494-501 [11839669.001]
  • [Cites] Arch Pathol Lab Med. 2002 Jun;126(6):676-85 [12033955.001]
  • [Cites] Int J Surg Pathol. 2005 Oct;13(4):329-35 [16273188.001]
  • (PMID = 20614263.001).
  • [ISSN] 1936-0568
  • [Journal-full-title] Head and neck pathology
  • [ISO-abbreviation] Head Neck Pathol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CKAP4 protein, human; 0 / Membrane Proteins
  • [Other-IDs] NLM/ PMC2807526
  • [Keywords] NOTNLM ; Metastatic renal cell carcinoma / Oncocytic carcinoma / Oncocytoma / p63
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42. Antic T, Perry KT, Harrison K, Zaytsev P, Pins M, Campbell SC, Picken MM: Mixed epithelial and stromal tumor of the kidney and cystic nephroma share overlapping features: reappraisal of 15 lesions. Arch Pathol Lab Med; 2006 Jan;130(1):80-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mixed epithelial and stromal tumor of the kidney and cystic nephroma share overlapping features: reappraisal of 15 lesions.
  • CONTEXT: Cystic nephroma is a rare cystic tumor, which only recently has been recognized as an exclusively adult lesion.
  • Mixed epithelial and stromal tumor of the kidney is also a rare, recently recognized, biphasic tumor composed of tubular and cystic elements embedded in grossly recognizable spindle cell stroma.
  • OBJECTIVES: To compare clinical phenotype, morphology, and immunohistochemistry in mixed epithelial and stromal tumor of the kidney and cystic nephroma in order to explore the relationship between these 2 lesions.
  • DESIGN: Fifteen biphasic lesions (8 mixed epithelial and stromal tumors of the kidney and 7 cystic nephromas) were studied.
  • RESULTS: Mixed epithelial and stromal tumor of the kidney occurred exclusively in women aged 36 to 80 years (mean, 49.7 years), all of whom had a history of estrogen therapy and/or obesity.
  • All 15 lesions were benign.
  • In mixed epithelial and stromal tumors of the kidney, the stroma was positive for estrogen and progesterone receptors in 4 of 5 lesions tested.
  • In cystic nephroma, focal positivity for hormone receptors was seen in 2 of 7 tumors tested; both positive lesions were from women.
  • The epithelial lining in both mixed epithelial and stromal tumor of the kidney and cystic nephroma lesions was variable with regard to shape, cytoplasmic appearance, and immunophenotype (with focal positivity for CD10, cytokeratin 7, high-molecular-weight keratin, and Ulex europaeus detectable in both lesions).
  • CONCLUSIONS: While mixed epithelial and stromal tumor of the kidney has a strong association with the female sex and hormonal milieu, cystic nephroma can affect both sexes and, on occasion, may also have hormonal associations.
  • Our studies also suggest that the tubules may be entrapped rather than comprising an intrinsic component of the tumor.
  • [MeSH-major] Kidney Neoplasms / pathology. Nephroma, Mesoblastic / pathology. Stromal Cells / pathology
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers, Tumor. Female. Humans. Immunoenzyme Techniques. Male. Middle Aged. Neoplasms, Glandular and Epithelial / metabolism. Neoplasms, Glandular and Epithelial / pathology. Receptors, Estrogen / metabolism. Receptors, Progesterone / metabolism

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  • (PMID = 16390243.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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43. Bishop JA, Sharma R, Illei PB: Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma. Hum Pathol; 2010 Jan;41(1):20-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Napsin A and thyroid transcription factor-1 expression in carcinomas of the lung, breast, pancreas, colon, kidney, thyroid, and malignant mesothelioma.
  • Immunohistochemistry for thyroid transcription factor-1 is widely used in the diagnosis of pulmonary adenocarcinomas because it marks approximately 75% of lung adenocarcinomas and is negative in most squamous cell carcinomas and adenocarcinomas of other organs.
  • We performed immunohistochemistry for napsin A and thyroid transcription factor-1 using tissue microarrays of 95 adenocarcinomas, 48 squamous cell carcinomas, 6 neuroendocrine tumors of the lung, as well as 5 colonic, 31 pancreatic, and 17 breast adenocarcinomas, 38 malignant mesotheliomas, 118 renal cell carcinomas, and 81 thyroid tumors.
  • The tissue microarrays also included 15 different benign tissues.
  • There were 13 napsin A-positive/thyroid transcription factor-1-negative and 2 thyroid transcription factor-1-positive/napsin A-negative tumors, increasing the number of cases that were positive with at least one of the markers to 81 (85%) of 95.
  • The limited number of neuroendocrine tumors tested was napsin A negative.
  • Of the renal tumors, napsin A was positive in most of papillary renal cell carcinomas (79%), about one third (34%) of clear cell renal cell carcinomas, and in a single case of chromophobe renal cell carcinoma (3%).
  • As expected, all renal tumors were thyroid transcription factor-1 negative, and all thyroid tumors, except for one papillary carcinoma, were thyroid transcription factor-1 positive.
  • Napsin A is a sensitive marker for pulmonary adenocarcinoma and is also expressed in a subset of renal cell carcinomas, particularly of the papillary type, as well as in rare cases of papillary thyroid carcinomas.
  • The combined use of napsin A and thyroid transcription factor-1 results in improved sensitivity and specificity for identifying pulmonary adenocarcinoma in primary lung tumors and in a metastatic setting.
  • [MeSH-major] Aspartic Acid Endopeptidases / metabolism. Biomarkers, Tumor / metabolism. Neoplasms / metabolism. Nuclear Proteins / metabolism. Transcription Factors / metabolism
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / metabolism. Breast Neoplasms / metabolism. Colonic Neoplasms / metabolism. Female. Humans. Immunohistochemistry. Kidney Neoplasms / metabolism. Lung Neoplasms / diagnosis. Lung Neoplasms / metabolism. Mesothelioma / diagnosis. Mesothelioma / metabolism. Pancreatic Neoplasms / metabolism. Thyroid Neoplasms / metabolism. Tissue Array Analysis

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  • [CommentIn] Hum Pathol. 2012 Jul;43(7):1153-4; author reply 1154 [22703591.001]
  • (PMID = 19740516.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Nuclear Proteins; 0 / Transcription Factors; 0 / thyroid nuclear factor 1; EC 3.4.23.- / Aspartic Acid Endopeptidases; EC 3.4.23.- / NAPSA protein, human
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44. Russo P: Should elective partial nephrectomy be performed for renal cell carcinoma &gt;4 cm in size? Nat Clin Pract Urol; 2008 Sep;5(9):482-3
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  • [Title] Should elective partial nephrectomy be performed for renal cell carcinoma >4 cm in size?
  • This Practice Point discusses the study of Pahernik and colleagues, which compared outcomes of partial nephrectomy between 102 patients with renal cell carcinoma >4 cm in size and 372 patients with tumors <or=4 cm in size.
  • This study adds to the growing literature base supporting partial nephrectomy for small renal masses whenever possible.
  • The rationale for further expanding the indications for partial nephrectomy includes the presence of indolent or benign tumor histology in 45% of patients, concerns that radical nephrectomy can cause or worsen pre-existing chronic kidney disease, and the possibility of metachronous contralateral tumor recurrence in a solitary kidney after radical nephrectomy.
  • Although technically more demanding than radical nephrectomy, partial nephrectomy provides equivalent oncological control while preserving renal function and preventing chronic kidney disease, and should be utilized whenever possible for the treatment of small renal masses.

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  • (PMID = 18648330.001).
  • [ISSN] 1743-4289
  • [Journal-full-title] Nature clinical practice. Urology
  • [ISO-abbreviation] Nat Clin Pract Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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45. Herawi M, Leppert JT, Thomas GV, De Kernion JB, Epstein JI: Implants of noninvasive papillary urothelial carcinoma in peritoneum and ileocolonic neobladder: support for "seed and soil" hypothesis of bladder recurrence. Urology; 2006 Apr;67(4):746-50
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  • OBJECTIVES: To explore the underlying mechanism of tumor regrowth in cases of noninvasive urothelial carcinoma that recur in unusual anatomic locations.
  • One had presented as an implant in the peritoneal investment of the bladder dome and the other as multiple implants growing on the benign surface of the colonic mucosa of an orthotopic neobladder distant from the anastomosis site.
  • Both cases had initially presented as noninvasive papillary urothelial carcinoma of the renal pelvis.
  • Although the urinary bladder was free of neoplastic changes at nephroureterectomy, both patients also developed several papillary tumors within the bladder shortly after the removal of the kidney.
  • CONCLUSIONS: After clinicopathologic correlation, the mode of tumor spread in these cases was best explained by the "seeding/implantation" theory.
  • The urothelial tumor cells in each of these cases demonstrated the ability to implant themselves not only in the urothelium of the bladder but also in the colonic mucosa of a constructed neobladder and on the peritoneal surface.
  • [MeSH-major] Carcinoma, Transitional Cell / secondary. Carcinoma, Transitional Cell / surgery. Neoplasm Recurrence, Local / etiology. Neoplasm Seeding. Peritoneal Neoplasms / secondary. Urinary Bladder Neoplasms / secondary. Urinary Bladder Neoplasms / surgery. Urinary Reservoirs, Continent

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  • (PMID = 16566991.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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46. Basic-Jukic N, Furic-Cunko V, Coric M, Bubic-Filipi LJ, Kastelan Z, Pasini J, Kes P: Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports. Transplant Proc; 2010 Jun;42(5):1704-7
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  • [Title] Appendiceal carcinoid and mucinous cystadenoma in renal transplant recipients: case reports.
  • There is an increased incidence of tumors among renal transplant patients, which are associated with immunosuppression.
  • Carcinoids are rare neuroendocrine tumors that arise from the enterochromaffin cells.
  • Although appendiceal carcinoid tumors are the commonest malignant neoplasms affecting the appendix, and mucinous cystadenoma is the commonest benign appendiceal neoplasm, they have not been reported in immunosuppressed patients.
  • We present two renal transplant recipients who developed combined appendiceal carcinoid and mucinous cystadenoma.
  • [MeSH-major] Appendiceal Neoplasms / etiology. Cystadenoma, Mucinous / etiology. Kidney Transplantation / adverse effects
  • [MeSH-minor] Adult. Female. Humans. Kidney Failure, Chronic / surgery. Magnetic Resonance Imaging. Male. Neoplasms / epidemiology. Neoplasms / etiology. Neoplasms / pathology. Neoplasms / surgery. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery

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  • (PMID = 20620505.001).
  • [ISSN] 1873-2623
  • [Journal-full-title] Transplantation proceedings
  • [ISO-abbreviation] Transplant. Proc.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Collins S, McKiernan J, Landman J: Update on the epidemiology and biology of renal cortical neoplasms. J Endourol; 2006 Dec;20(12):975-85
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  • [Title] Update on the epidemiology and biology of renal cortical neoplasms.
  • A new era is developing in the understanding of the diagnosis, classification, and management of renal-cell carcinoma (RCC).
  • Nevertheless, many incidental lesions prove to be benign, so there is renewed enthusiasm for biopsy before treatment is selected.
  • Genetic conditions associated with RCC, such as Von Hippel Lindau and Birt-Hogg-Dube syndromes, along with genetic analyses of tumors, have provided considerable insight into the pathogenesis of these lesions.
  • Renal-cell carcinoma is resistant to chemotherapy, and high-dose interleukin-2 is the only regimen currently approved by the Food and Drug Administration for the treatment of advanced RCC.

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  • (PMID = 17206887.001).
  • [ISSN] 0892-7790
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 72
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48. Arkadopoulos N, Karapanos K, Stafyla V, Yiallourou A, Koureas A, Kondi-Pafiti A, Smyrniotis V: Combination of right nephrectomy and total pancreaticoduodenectomy for Von Hippel-Lindau disease. JOP; 2010;11(3):270-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Combination of right nephrectomy and total pancreaticoduodenectomy for Von Hippel-Lindau disease.
  • CONTEXT: Von Hippel-Lindau disease is an inherited syndrome of multiorgan neoplasia caused by a germline mutation in the von Hippel-Lindau gene and can include central nervous system tumors, renal cell carcinomas and benign pancreatic cystic tumors.
  • Imaging revealed renal tumors and multiple pancreatic tumors which caused duodenal and pancreatic duct compression.
  • Pathology identified a multifocal unilateral clear cell renal carcinoma which interestingly coexisted with multiple large pancreatic serous microcystic adenomas with infiltration of the fibrous capsule.
  • CONCLUSION: In past cases of von Hippel-Lindau disease, pancreatic adenomas with malignant transformation have not been reported.
  • [MeSH-major] Carcinoma, Renal Cell / surgery. Neoplasms, Multiple Primary / surgery. Nephrectomy / methods. Pancreatic Neoplasms / surgery. Pancreaticoduodenectomy / methods. von Hippel-Lindau Disease / surgery


49. Remzi M, Ozsoy M, Klingler HC, Susani M, Waldert M, Seitz C, Schmidbauer J, Marberger M: Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter. J Urol; 2006 Sep;176(3):896-9
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  • [Title] Are small renal tumors harmless? Analysis of histopathological features according to tumors 4 cm or less in diameter.
  • PURPOSE: Small renal tumors detected incidentally are considered to have less aggressive potential.
  • MATERIALS AND METHODS: We reviewed data of 287 tumor bearing kidneys in which solid tumors 4 cm or less in diameter were detected by cross-sectional imaging and subsequently removed surgically.
  • Tumor size as documented by preoperative computerized tomography was correlated to histological diagnosis, and in cases of malignancy correlated to tumor type, pathological TNM stage and nuclear (Fuhrman) grade.
  • With multifocal lesions the largest single tumor was considered the reference lesion but multifocality was also considered a separate parameter.
  • RESULTS: At a mean tumor diameter of 2.94 +/- 0.87 cm 65 (22.6%) tumors were 2 cm or less, 103 (35.9%) were 2.1 to 3.0 cm and 119 (41.5%) were 3.1 to 4 cm in diameter.
  • A total of 56 (19.5%) tumors were benign with no correlation to tumor size (Pearson test p = 0.660).
  • Renal cell cancer was found in 227 (79.1%) patients with 159 (70.0%) clear cell, 47 (20.7%) papillary, 11 (4.8%) chromophobe and 10 others with no correlation to tumor diameter.
  • Of the kidneys 31 (13.6%) had multifocal renal cell carcinoma, with a significant correlation to larger tumor diameter (linear regression p = 0.048) and papillary renal cell carcinoma subtype (linear regression p = 0.018).
  • Two (4.2%), 4 (5%) and 25 (25.5%) cases of renal cell carcinoma 2 cm or less, 2.1 to 3 cm and 3.1 to 4 cm in diameter had Fuhrman grade G3/4, respectively (Pearson p = 0.0007).
  • Whereas distant metastases were diagnosed in only 4 patients with renal cell carcinoma with tumors 3 cm or less, distant metastases were in 10 (8.4%) patients with tumors 3.1 to 4 cm (p = 0.045).
  • CONCLUSIONS: The aggressive potential of small renal cell carcinoma increases dramatically beyond a tumor diameter of 3 cm.
  • Given the difficulty in measuring tumor diameters reliably with sequential imaging studies, the threshold for selecting patients for a surveillance strategy should be set well under this parameter.
  • [MeSH-major] Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology

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  • [CommentIn] Nat Clin Pract Urol. 2007 Mar;4(3):124-5 [17290248.001]
  • (PMID = 16890647.001).
  • [ISSN] 0022-5347
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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50. Fass G, Hossey D, Nyst M, Smets D, Saligheh EN, Duttmann R, Claes K, da Costa PM: Benign retroperitoneal schwannoma presenting as colitis: a case report. World J Gastroenterol; 2007 Nov 7;13(41):5521-4
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  • [Title] Benign retroperitoneal schwannoma presenting as colitis: a case report.
  • Histopathology and immunohistochemistry revealed benign retroperitoneal schwannoma.
  • These neural sheath tumors rarely occur in the retroperitoneum.
  • They are usually asymptomatic but as they enlarge they may compress adjacent structures, which leads to a wide spectrum of non-specific symptoms, including lumbar pain, headache, secondary hypertension, abdominal pain and renal colicky pain.
  • Diagnosis is based on histopathological examination and immunohistochemistry.
  • [MeSH-major] Colitis / etiology. Neurilemmoma / diagnosis. Retroperitoneal Neoplasms / diagnosis
  • [MeSH-minor] DNA Mutational Analysis. Diagnosis, Differential. Female. Gene Expression Regulation, Neoplastic. Genes, Neurofibromatosis 2. Humans. Magnetic Resonance Imaging. Middle Aged. Mutation. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 17907300.001).
  • [ISSN] 1007-9327
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC4171291
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51. DeRoche T, Walker E, Magi-Galluzzi C, Zhou M: Pathologic characteristics of solitary small renal masses: can they be predicted by preoperative clinical parameters? Am J Clin Pathol; 2008 Oct;130(4):560-4
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  • [Title] Pathologic characteristics of solitary small renal masses: can they be predicted by preoperative clinical parameters?
  • We studied the pathologic features and whether clinical features could predict pathologic outcomes in small renal masses.
  • The study included all adult patients with solitary, nonmetastatic renal masses 4 cm or smaller confirmed by nephrectomy or needle biopsy between 2004 and 2006.
  • Tumor size, histologic type, Fuhrman nuclear grade, and stage were obtained from surgical pathology reports.
  • Clinical variables included age, sex, tumor size, and symptomatology.
  • Median tumor size was 2.6 cm (range, 0.5-4.0 cm).
  • Nonneoplastic entities, benign neoplasms, and low- and high-grade carcinoma accounted for 1.6%, 18.0%, 49.0%, and 31.4% of masses, respectively.
  • Women were more likely to have a benign mass (27.3% vs 14.5% of men, P < .001).
  • Age (P = .56), tumor size (mean, 2.63 vs 2.46 cm for benign; P = .08), and symptomatology (P = .46) were not associated with malignancy.
  • Multivariate analyses using sex, age, tumor size, and symptomatology failed to produce a model useful to predict the pathology of individual tumors.
  • [MeSH-major] Kidney Diseases / pathology. Kidney Neoplasms / pathology

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  • (PMID = 18794048.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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52. Moslemi MK: Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update. Urol J; 2010;7(3):141-7
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  • [Title] Mixed epithelial and stromal tumor of the kidney or adult mesoblastic nephroma: an update.
  • PURPOSE: Our aim was to review the spectrum of usual and unusual clinical and morphologic findings observed in mixed epithelial and stromal tumor of the kidney (MEST).
  • RESULTS: Mixed epithelial and stromal tumor is a relatively rare and distinct neoplasm of the kidney that should be distinguished from other renal neoplasms.
  • Although the overall prognosis is favorable, recurrence and malignant transformation of MEST can occur CONCLUSION: It is difficult to distinguish benign or malignant nature on imaging studies.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Nephroma, Mesoblastic / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans


53. Schoth F, Persigehl T, Palmowski M: Current role and future perspective of MRI for diagnosis and characterization of renal cell carcinoma. Panminerva Med; 2010 Dec;52(4):307-18
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  • [Title] Current role and future perspective of MRI for diagnosis and characterization of renal cell carcinoma.
  • During the past years, magnetic resonance imaging (MRI) has been established as a reliable method for examination of the kidneys.
  • Modern MRI systems enable to visualize renal masses with a high spatial resolution.
  • This enables not only to differentiate between benign lesions and renal cancer but also to define the tumor stage with high accuracy.
  • Tumor-related infiltration of the renal pelvis, infiltration of the perinephric fat or a tumor thrombus within the inferior caval vein has to be diagnosed with high accuracy to enable these stage adapted treatment regimens.
  • This article introduces into clinically established "morphologic" MRI techniques for diagnosis and staging of renal cell carcinoma (RCC).
  • Besides detection and staging of kidney cancer, the recent development of molecularly targeted therapies in patients with metastatic or non-operable tumors has led to novel diagnostic demands.
  • To evaluate treatment efficiency, more information than just tumor morphology should be provided.
  • [MeSH-major] Carcinoma, Renal Cell / diagnosis. Kidney Neoplasms / diagnosis. Magnetic Resonance Imaging / trends
  • [MeSH-minor] Humans. Neoplasm Invasiveness. Neoplasm Staging. Predictive Value of Tests. Treatment Outcome


54. Kokubo T, Kakinuma S, Kobayashi T, Watanabe F, Iritani R, Tateno K, Nishimura M, Nishikawa T, Hino O, Shimada Y: Age dependence of radiation-induced renal cell carcinomas in an Eker rat model. Cancer Sci; 2010 Mar;101(3):616-23
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  • [Title] Age dependence of radiation-induced renal cell carcinomas in an Eker rat model.
  • Toward this goal, we assessed the risk of developing renal cell carcinoma using Eker rats as a kidney tumor model.
  • At 27 weeks of age, kidneys were examined for proliferative lesions.
  • Irrespective of LOH, the mTOR (mammalian target of rapamycin) pathway, which is negatively regulated by the Tsc1/2 complex, was activated in both benign and malignant lesions, as evidenced by phosphorylation of S6 ribosomal protein and 4E-BP1.
  • In conclusion, actively growing kidneys in perinatal-aged (F344 x Eker) F1 rats (Tsc2(+/-)) are at risk for radiation-induced malignant transformation of the renal epithelium associated with mTOR activation.
  • [MeSH-major] Carcinoma, Renal Cell / etiology. Kidney Neoplasms / etiology. Neoplasms, Radiation-Induced / etiology. Tumor Suppressor Proteins / genetics

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  • (PMID = 20132221.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Intracellular Signaling Peptides and Proteins; 0 / Tumor Suppressor Proteins; 4JG2LF96VF / tuberous sclerosis complex 2 protein; EC 2.7.1.1 / TOR Serine-Threonine Kinases; EC 2.7.1.1 / mTOR protein, rat; EC 2.7.11.1 / Protein-Serine-Threonine Kinases; EC 2.7.11.1 / Proto-Oncogene Proteins c-akt
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55. Callstrom MR, Charboneau JW: Percutaneous ablation: safe, effective treatment of bone tumors. Oncology (Williston Park); 2005 Oct;19(11 Suppl 4):22-6
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  • [Title] Percutaneous ablation: safe, effective treatment of bone tumors.
  • Percutaneous radiofrequency ablation (RFA) of osteoid osteomas has replaced surgical excision as the preferred method for treatment of these benign lesions, due to high effectiveness and low morbidity.
  • Both RFA and cryoablation are safe and effective for palliation of pain due to metastatic disease in patients who have failed conventional therapies.
  • These image-guided treatments can be performed precisely, allowing safe treatment of complex metastatic tumors.
  • [MeSH-major] Bone Neoplasms / therapy. Catheter Ablation / instrumentation. Catheter Ablation / methods. Osteoma, Osteoid / therapy
  • [MeSH-minor] Aged. Bone Cements / therapeutic use. Carcinoma, Renal Cell / pathology. Electrodes. Follow-Up Studies. Fractures, Bone / pathology. Fractures, Bone / radiography. Fractures, Bone / therapy. Humans. Male. Melanoma / pathology. Neoplasm Metastasis / therapy. Palliative Care. Patient Selection. Prospective Studies. Quality of Life. Time Factors. Tomography, X-Ray Computed. Treatment Outcome

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  • (PMID = 16366375.001).
  • [ISSN] 0890-9091
  • [Journal-full-title] Oncology (Williston Park, N.Y.)
  • [ISO-abbreviation] Oncology (Williston Park, N.Y.)
  • [Language] eng
  • [Publication-type] Case Reports; Comparative Study; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Bone Cements
  • [Number-of-references] 24
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56. Rowsell C, Fleshner N, Marrano P, Squire J, Evans A: Papillary renal cell carcinoma within a renal oncocytoma: case report of an incidental finding of a tumour within a tumour. J Clin Pathol; 2007 Apr;60(4):426-8
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  • [Title] Papillary renal cell carcinoma within a renal oncocytoma: case report of an incidental finding of a tumour within a tumour.
  • The most common renal tumours are clear cell, papillary, chromophobe and collecting duct renal cell carcinomas (RCCs), and benign oncocytomas and angiomyolipomas.
  • Tumours with hybrid features between some of these entities have been recognised; in particular, tumours with features of both chromophobe RCC and oncocytoma.
  • Case reports describing one distinct type of primary renal tumour actually within another are very rare.
  • The incidental finding of a papillary RCC located in an oncocytoma in a nephrectomy specimen from a 75-year-old man is described.
  • Morphological criteria for each tumour type were completely satisfied and fluorescence in situ hybridisation detected the expected number of copies of chromosome 7 in the cells of each tumour type.
  • The cells in the papillary tumour contained three copies, whereas the oncocytoma cells contained only two per nucleus.
  • [MeSH-major] Adenoma, Oxyphilic / pathology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / pathology. Mixed Tumor, Malignant / pathology


57. Dogan B, Akbulut Z, Canda AE, Balbay MD: Re: Effect of reclassification on the incidence of benign and malignant renal tumors. T. A. Skolarus, M. F. Serrano, R. L. Grubb, III, M. D. Katz, T. L. Bullock, F. Gao, P. A. Humphrey and A. S. Kibel J Urol 2010; 183: 455-458. J Urol; 2010 Sep;184(3):1222
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  • [Title] Re: Effect of reclassification on the incidence of benign and malignant renal tumors. T. A. Skolarus, M. F. Serrano, R. L. Grubb, III, M. D. Katz, T. L. Bullock, F. Gao, P. A. Humphrey and A. S. Kibel J Urol 2010; 183: 455-458.
  • [MeSH-major] Kidney Neoplasms / epidemiology

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  • [CommentOn] J Urol. 2010 Feb;183(2):455-8 [20006852.001]
  • (PMID = 20650500.001).
  • [ISSN] 1527-3792
  • [Journal-full-title] The Journal of urology
  • [ISO-abbreviation] J. Urol.
  • [Language] eng
  • [Publication-type] Comment; Letter
  • [Publication-country] United States
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58. Katabathina VS, Vikram R, Nagar AM, Tamboli P, Menias CO, Prasad SR: Mesenchymal neoplasms of the kidney in adults: imaging spectrum with radiologic-pathologic correlation. Radiographics; 2010 Oct;30(6):1525-40
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  • [Title] Mesenchymal neoplasms of the kidney in adults: imaging spectrum with radiologic-pathologic correlation.
  • Mesenchymal neoplasms of the kidney in adults cover a wide spectrum with characteristic ontogeny and histologic findings and variable biologic profiles and imaging findings.
  • Benign mesenchymal renal tumors include angiomyolipoma, leiomyoma, hemangioma, lymphangioma, juxtaglomerular cell tumor, renomedullary interstitial cell tumor (medullary fibroma), lipoma, solitary fibrous tumor, and schwannoma.
  • Malignant renal tumors of mesenchymal origin include leiomyosarcoma, rhabdomyosarcoma, angiosarcoma, osteosarcoma, synovial sarcoma, fibrosarcoma, malignant fibrous histiocytoma, and solitary fibrous tumor.
  • Cross-sectional imaging findings for mesenchymal renal tumors in adults are varied.
  • Renal hemangioma may show phleboliths and a characteristic enhancement pattern.
  • Leiomyoma typically arises from the capsule and causes buckling of the renal cortex.
  • Although osteosarcoma may demonstrate characteristic dense ossification, most renal sarcomas demonstrate imaging features that are indistinguishable from the more common renal cell carcinoma.
  • Although some renal mesenchymal tumors have typical imaging findings, biopsy is warranted to establish a definitive diagnosis.
  • Awareness of the various mesenchymal renal tumors and familiarity with their imaging findings permit optimal patient management.
  • [MeSH-major] Diagnostic Imaging. Kidney Neoplasms / diagnosis. Mesoderm / pathology
  • [MeSH-minor] Adult. Biopsy. Diagnosis, Differential. Humans

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  • [Copyright] © RSNA, 2010.
  • (PMID = 21071373.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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59. Jang HJ, Lee JY, Lee DH, Kim WH, Hwang JH: Current and Future Clinical Applications of High-Intensity Focused Ultrasound (HIFU) for Pancreatic Cancer. Gut Liver; 2010 Sep;4 Suppl 1:S57-61
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  • High-intensity focused ultrasound (HIFU) is a novel therapeutic modality that permits noninvasive treatment of various benign and malignant solid tumors, including prostatic cancer, uterine fibroids, hepatic tumors, renal tumors, breast cancers, and pancreatic cancers.
  • Several preclinical and clinical studies have investigated the safety and efficacy of HIFU for treating solid tumors, including pancreatic cancer.

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  • [Cites] IRE Trans Med Electron. 1960 Jul;ME-7:166-81 [13702332.001]
  • [Cites] Ultrasound Med Biol. 1987 Feb;13(2):69-76 [3590362.001]
  • [Cites] Prostate. 2004 Feb 1;58(2):109-20 [14716736.001]
  • [Cites] Radiology. 2005 Feb;234(2):431-7 [15671000.001]
  • [Cites] Radiology. 2005 Sep;236(3):1034-40 [16055692.001]
  • [Cites] Clin Cancer Res. 2005 Dec 15;11(24 Pt 1):8782-8 [16361566.001]
  • [Cites] J Acoust Soc Am. 2006 Mar;119(3):1834-48 [16583923.001]
  • [Cites] Am J Surg. 2006 Aug;192(2):179-84 [16860626.001]
  • [Cites] Ultrasound Med Biol. 2006 Oct;32(10):1611-9 [17045882.001]
  • [Cites] Int J Hyperthermia. 2007 Mar;23(2):165-71 [17578340.001]
  • [Cites] Ultrasound Med Biol. 2008 Jan;34(1):81-7 [17854983.001]
  • [Cites] Cryobiology. 2009 Feb;58(1):1-11 [19007768.001]
  • [Cites] Ultrasound Med Biol. 2009 Mar;35(3):416-24 [19081668.001]
  • [Cites] Ultrasound Med Biol. 2009 Jun;35(6):967-75 [19201519.001]
  • [Cites] Radiology. 2009 Apr;251(1):58-66 [19251937.001]
  • [Cites] JOP. 2009;10(2):123-9 [19287104.001]
  • [Cites] Korean J Gastroenterol. 2009 Apr;53(4):216-20 [19381053.001]
  • [Cites] Anticancer Drugs. 2010 Apr;21(4):447-52 [20075714.001]
  • [Cites] Ultrasound Med Biol. 2010 Mar;36(3):441-8 [20172447.001]
  • [Cites] J Acoust Soc Am. 1990 Nov;88(5):2059-69 [2269722.001]
  • [Cites] Am J Phys Med. 1955 Jun;34(3):413-23 [14376518.001]
  • (PMID = 21103296.001).
  • [ISSN] 2005-1212
  • [Journal-full-title] Gut and liver
  • [ISO-abbreviation] Gut Liver
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC2989544
  • [Keywords] NOTNLM ; High-intensity focused ultrasound / Pancreatic cancer / Review / Therapy
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60. Petillo D, Kort EJ, Anema J, Furge KA, Yang XJ, Teh BT: MicroRNA profiling of human kidney cancer subtypes. Int J Oncol; 2009 Jul;35(1):109-14
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  • [Title] MicroRNA profiling of human kidney cancer subtypes.
  • In order to understand their role in renal tumorigenesis, we screened the expression levels of miRNAs in four subtypes of human renal neoplasms: clear cell, papillary, and chromophobe renal cell carcinomas (RCC) as well as benign renal oncocytomas.
  • We found a unique miRNA signature for each subtype of renal tumor.
  • Specifically, we documented the overexpression of miRs 424 and 203 in clear cell RCC relative to papillary RCC, as well as the inversion of expression of miR-203 in the benign oncocytomas (where it is underexpressed relative to normal kidney) as compared to the malignant chromophobe RCC (where it is overexpressed relative to normal kidney).
  • While previous studies have identified unique miRNA expression pattern distinguishing tumors from different anatomical locations, here we extend this principle to demonstrate the utility of miRNA expression profiling to identify a signature unique to various tumor subtypes at a single anatomic locus.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. Carcinoma, Renal Cell / genetics. Gene Expression Profiling / methods. Kidney Neoplasms / genetics. MicroRNAs / analysis

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  • (PMID = 19513557.001).
  • [ISSN] 1019-6439
  • [Journal-full-title] International journal of oncology
  • [ISO-abbreviation] Int. J. Oncol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Greece
  • [Chemical-registry-number] 0 / MicroRNAs
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61. Knezević V, Poljak M, Bradamante Z, Serman D, Levak-Svajger B, Svajger A: Yolk sac carcinoma derived from the rat epiblast as a renal isograft. Coll Antropol; 2005 Jun;29(1):189-97
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  • [Title] Yolk sac carcinoma derived from the rat epiblast as a renal isograft.
  • We report the novel observation that a biphasic, parieto-visceral (PYS/VYS) yolk sac carcinoma can develop from the isolated epiblast of the pre-primitive streak rat embryo in a prolonged cultivation in vivo as a renal isograft.
  • From the rest of the cylinder the 4 cell layers were isolated and transplanted separately under the kidney capsule of isogenic adult males.
  • After 4 weeks the hypoblast was resorbed, the extraembryonic ectoderm gave rise to hemorrhagic cysts and trophoblastic giant cells, the extraembryonic (visceral yolk sac) endoderm formed benign cystic PYS/VYS tumors, and the epiblast developed into a benign teratoma.
  • It destroyed the teratoma and the recipient's kidney, metastasized to peritoneum and other sites, and caused abundant ascites containing clustered tumor cells.
  • The primary tumor was retransplantable subcutaneously as well as intraperitoneally, and displayed the characteristics of the mixed or biphasic PVYS carcinoma, with a progressive loss of the VYS component with time.
  • [MeSH-major] Carcinoma / pathology. Carcinoma / veterinary. Endodermal Sinus Tumor / pathology. Endodermal Sinus Tumor / veterinary. Kidney Neoplasms / pathology. Kidney Neoplasms / veterinary. Teratoma / pathology. Teratoma / veterinary
  • [MeSH-minor] Animals. Ascites. Ectoderm. Embryo, Mammalian. Female. Kidney / pathology. Male. Neoplasm Metastasis. Neoplasms, Experimental. Rats. Transplants

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  • (PMID = 16117321.001).
  • [ISSN] 0350-6134
  • [Journal-full-title] Collegium antropologicum
  • [ISO-abbreviation] Coll Antropol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Croatia
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62. Ip YT, Yuan JQ, Cheung H, Chan JK: Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor? Am J Surg Pathol; 2010 Nov;34(11):1695-700
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  • [Title] Sporadic hemangioblastoma of the kidney: an underrecognized pseudomalignant tumor?
  • Hemangioblastoma is a benign tumor that can occur sporadically, or in association with von Hippel-Lindau disease in approximately one-quarter of the cases.
  • This report describes 2 cases of sporadic renal hemangioblastoma, with 1 patient presenting with hematuria and polycythemia, and the other low back pain.
  • Histologically, the tumors were circumscribed, and composed of sheets of large polygonal cells traversed by arborizing thin-walled blood vessels.
  • Many of the tumor cells showed pleomorphic nuclei, but the mitotic figures were rare.
  • The diagnosis of hemangioblastoma was confirmed by negative immunostaining for cytokeratin, and positive staining for α-inhibin, S100, and neuron-specific enolase.
  • This benign neoplasm which can be mistaken for various malignancies such as renal cell carcinoma, epithelioid angiomyolipoma, adrenal cortical carcinoma, and paraganglioma, deserves wider recognition for its occurrence as a primary renal tumor.
  • [MeSH-major] Hemangioblastoma / pathology. Kidney Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Female. Hematuria / etiology. Humans. Immunohistochemistry. Inhibins / analysis. Keratins / analysis. Low Back Pain / etiology. Male. Middle Aged. Nephrectomy. Phosphopyruvate Hydratase / analysis. Polycythemia / etiology. S100 Proteins / analysis

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  • [CommentIn] Am J Surg Pathol. 2011 Apr;35(4):623-4 [21378542.001]
  • (PMID = 20924277.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / S100 Proteins; 0 / inhibin-alpha subunit; 57285-09-3 / Inhibins; 68238-35-7 / Keratins; EC 4.2.1.11 / Phosphopyruvate Hydratase
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63. Zheng W, Yi X, Fadare O, Liang SX, Martel M, Schwartz PE, Jiang Z: The oncofetal protein IMP3: a novel biomarker for endometrial serous carcinoma. Am J Surg Pathol; 2008 Feb;32(2):304-15
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  • Insulin-like growth factor II mRNA-binding protein 3 (IMP3) is an oncofetal protein highly expressed in fetal tissue and malignant tumors but rarely found in adult benign tissues.
  • The aim of this study is to determine the expression of IMP3 in benign endometrium, endometrial cancer, and its precursor lesions, trying to see whether IMP3 has any diagnostic usage.
  • These included benign endometrium (n=68), atypical hyperplasia or endometrial intraepithelial neoplasia (n=35), endometrial glandular dysplasia (n=21), endometrial intraepithelial carcinoma (n=18), endometrioid carcinoma (n=70), mucinous carcinoma (n=8), serous carcinoma (n=51), clear cell carcinoma (n=12), and other malignancies (n=15).
  • Maturational patterns in the 68 benign endometrial samples included atrophic (n=12), proliferative (n=18), secretory (n=14), menstrual (n=8), and gestational (n=16).
  • Most of the carcinomas were histologically pure; where mixed, the second component constituted <10% of the total tumor volume.
  • A renal cell carcinoma with known IMP3 expression was used as positive control for each immunohistochemistry run.
  • In contrast, the frequency of IMP3 expression was significantly lesser in nonserous malignancies with 0 (0%) of 35, 5 (7%) of 70, 0 (0%) of 8, 3 (25%) of 12, and 5 (33%) of 15 positive expression rates in atypical hyperplasia or endometrial intraepithelial neoplasia, endometrioid, mucinous, clear cell carcinomas, and other malignancies, respectively.
  • Among the benign endometrial samples, decidualized endometrial stroma showed 100% positivity for IMP3.
  • Although the significance of the latter finding remains unclear, the differential diagnosis between decidual changes and endometrial serous carcinoma is rarely problematic.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Cystadenocarcinoma, Serous / metabolism. Endometrial Neoplasms / metabolism. Neoplasm Proteins / metabolism. RNA-Binding Proteins / metabolism

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  • (PMID = 18223334.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA23074
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / IMP3 protein, human; 0 / Neoplasm Proteins; 0 / RNA-Binding Proteins
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64. Bensalah K, Pantuck AJ, Crepel M, Verhoest G, Méjean A, Valéri A, Ficarra V, Pfister C, Ferrière JM, Soulié M, Cindolo L, De La Taille A, Tostain J, Chautard D, Schips L, Zigeuner R, Abbou CC, Lobel B, Salomon L, Lechevallier E, Descotes JL, Guillé F, Colombel M, Belldegrun AS, Patard JJ: Prognostic variables to predict cancer-related death in incidental renal tumours. BJU Int; 2008 Nov;102(10):1376-80
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  • [Title] Prognostic variables to predict cancer-related death in incidental renal tumours.
  • OBJECTIVE: To identify, in a large multicentre series of incidental renal tumours, the key factors that could predict cancer-related deaths, as such tumours have a better outcome than symptomatic tumours and selected patients are increasingly being included in watchful-waiting protocols.
  • PATIENTS AND METHODS: Data from 3912 patients were extracted from three international kidney-cancer databases.
  • Age, gender, Eastern Cooperative Oncology Group (ECOG) performance status (PS), Tumour-Node-Metastasis (TNM) stage, tumour size, Fuhrman grade, and final pathology were recorded.
  • Benign tumours and malignant lesions with incomplete information were excluded from final analysis.
  • RESULTS: The mean (SD) age of the patients was 60.6 (12.2) years and the mean tumour size 5.5 (3.5) cm.
  • Most tumours were malignant (90.2%) and of low stage (T1-T2, 71.7%) and low grade (G1-G2, 72.4%).
  • In all, 525 (14.4%) patients died from cancer; in this group, tumours were >4 cm in 88.2% and had nodal or distant metastases in 20.2% and 49.3%, respectively.
  • Multivariable analysis showed that tumour size >4 cm, ECOG PS >or=1, TNM stage and Fuhrman grade were independent predictors of cancer-related death.
  • CONCLUSION: A significant proportion of incidental renal tumours can lead to the death of the patient.
  • Standard prognostic variables for renal cell carcinoma appear to remain valid for this subset of patients.
  • A watchful-waiting strategy should not be recommended if the tumour diameter is >4 cm, if biopsy confirms high-grade tumours, or if there is an impaired ECOG PS, or computed tomography findings suggest the presence of advanced T stage.
  • [MeSH-major] Carcinoma, Renal Cell / mortality. Incidental Findings. Kidney Neoplasms / mortality
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Multivariate Analysis. Neoplasm Staging. Nephrectomy / methods. Prognosis. Retrospective Studies. Survival Analysis. Young Adult


65. Rajaram V, Knezevich S, Bove KE, Perry A, Pfeifer JD: DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation. Genes Chromosomes Cancer; 2007 May;46(5):508-13
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  • Undifferentiated embryonal sarcoma of the liver is a highly malignant and aggressive tumor that occasionally arises within mesenchymal hamartoma of the liver (MHL), a benign tumor that typically occurs in young children.
  • MALAT1 is rearranged in renal tumors harboring the t(6;11)(p21;q13) translocation, and noncoding MALAT1 transcripts are overexpressed in a number of human carcinomas.
  • [MeSH-major] Chromosomes, Human, Pair 11. Chromosomes, Human, Pair 19. DNA, Neoplasm / genetics. Hamartoma / genetics. Liver Neoplasms / genetics. Sarcoma / genetics. Translocation, Genetic

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  • [Copyright] (c) 2007 Wiley-Liss, Inc.
  • (PMID = 17311249.001).
  • [ISSN] 1045-2257
  • [Journal-full-title] Genes, chromosomes & cancer
  • [ISO-abbreviation] Genes Chromosomes Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / DNA Primers; 0 / DNA, Neoplasm
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66. Gasparre G, Hervouet E, de Laplanche E, Demont J, Pennisi LF, Colombel M, Mège-Lechevallier F, Scoazec JY, Bonora E, Smeets R, Smeitink J, Lazar V, Lespinasse J, Giraud S, Godinot C, Romeo G, Simonnet H: Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma. Hum Mol Genet; 2008 Apr 1;17(7):986-95
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clonal expansion of mutated mitochondrial DNA is associated with tumor formation and complex I deficiency in the benign renal oncocytoma.
  • Here we show a benign tumor type in which mtDNA mutations that lead to complex I (CI) enzyme deficiency are found in all tumors and are the only genetic alteration detected.
  • Actually renal oncocytomas are homogeneous tumors characterized by dense accumulation of mitochondria and we had found that they are deficient in electron transport chain complex I (CI, NADH-ubiquinone oxidoreductase).
  • In this work total sequencing of mtDNA showed that 9/9 tumors harbored point mutations in mtDNA, seven in CI genes, one in complex III, and one in the control region.
  • All tumors were somatically deficient for CI.
  • The clonal amplification of mutated mtDNA in 8/9 tumors demonstrates that these alterations are selected and therefore favor or trigger growth.
  • [MeSH-major] Adenoma, Oxyphilic / genetics. DNA, Mitochondrial / genetics. Electron Transport Complex I / genetics. Kidney Neoplasms / genetics

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  • (PMID = 18156159.001).
  • [ISSN] 1460-2083
  • [Journal-full-title] Human molecular genetics
  • [ISO-abbreviation] Hum. Mol. Genet.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / DNA, Mitochondrial; 0 / Electron Transport Chain Complex Proteins; 0 / HIF1A protein, human; 0 / Hypoxia-Inducible Factor 1, alpha Subunit; 0 / RNA, Messenger; EC 1.6.5.3 / Electron Transport Complex I; EC 1.6.99.3 / NADH Dehydrogenase; EC 2.3.3.1 / Citrate (si)-Synthase; EC 2.7.7.- / POLG protein, human; EC 2.7.7.7 / DNA-Directed DNA Polymerase; IY9XDZ35W2 / Glucose
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67. Walsh CA, Quinlan DM: Oncocytoma and synchronous urothelial carcinoma in same kidney: previously unreported association. Urology; 2005 Jul;66(1):194
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  • [Title] Oncocytoma and synchronous urothelial carcinoma in same kidney: previously unreported association.
  • Many cases of histologically distinct renal tumors occurring coincidentally in the same patient have been reported.
  • We report the first case of a benign oncocytoma and a urothelial carcinoma occurring synchronously in the same kidney in a man who underwent radical nephrectomy for a suspicious renal mass.
  • [MeSH-major] Adenoma, Oxyphilic / surgery. Carcinoma, Transitional Cell / surgery. Kidney Neoplasms / surgery. Neoplasms, Multiple Primary / surgery

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  • (PMID = 15921729.001).
  • [ISSN] 1527-9995
  • [Journal-full-title] Urology
  • [ISO-abbreviation] Urology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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68. Song TK, Harris EJ Jr, Raghavan S, Norton JA: Major blood vessel reconstruction during sarcoma surgery. Arch Surg; 2009 Sep;144(9):817-22
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  • PATIENTS: Fourteen patients (10 female) with retroperitoneal or extremity sarcomas and major blood vessel involvement who underwent surgery to remove the tumor and had blood vessel reconstruction between 2003 and 2008.
  • MAIN OUTCOME MEASURES: Early (<30 days) and late (>30 days) operative morbidity and mortality, freedom from disease, and graft patency.
  • Thirteen tumors were malignant (7 high grade and 6 low grade) and 1, benign (leiomyoma).
  • In all, 16 arteries were reconstructed (2 common femoral; 5 iliac; 2 superficial femoral; 1 brachial; 1 popliteal; and 2 aorta, one with implantation of both iliac arteries and the other with implantation of the left renal, superior mesenteric, and hepatic arteries).
  • Five-year disease-free and overall survival were 52% and 68%, respectively.
  • [MeSH-major] Retroperitoneal Neoplasms / surgery. Sarcoma / surgery. Soft Tissue Neoplasms / surgery. Vascular Neoplasms / surgery. Vascular Surgical Procedures

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  • (PMID = 19797105.001).
  • [ISSN] 1538-3644
  • [Journal-full-title] Archives of surgery (Chicago, Ill. : 1960)
  • [ISO-abbreviation] Arch Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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69. Williams K, Fernandez S, Stien X, Ishii K, Love HD, Lau YF, Roberts RL, Hayward SW: Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype. Prostate; 2005 Jun 1;63(4):369-84
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  • [Title] Unopposed c-MYC expression in benign prostatic epithelium causes a cancer phenotype.
  • Human prostate cancers frequently display DNA amplification in the 8q24 amplicon, which leads to an increase in the copy number of the c-MYC gene, a finding that suggests a role for c-MYC in human prostate carcinogenesis.
  • These cells were recombined with inductive rat urogenital sinus mesenchyme and grafted beneath the renal capsule of immunocompromised rodent hosts.
  • The tumors were rapidly growing with a high proliferative index.
  • The neoplastic cells in the tumor expressed both androgen receptors (AR) and prostate-specific antigen (PSA), both characteristic markers of human prostate cancers.
  • Control grafts using either uninfected huPrE or using huPrE cells infected using an empty vector expressing a green fluorescent protein tag gave rise to well differentiated benign prostatic glandular ducts.
  • [MeSH-major] Adenocarcinoma / genetics. Prostate / cytology. Prostate / physiology. Prostatic Neoplasms / genetics. Proto-Oncogene Proteins c-myc / genetics
  • [MeSH-minor] Animals. Biomarkers, Tumor. Cells, Cultured. Disease Models, Animal. Epithelium / physiology. Gene Expression Regulation, Neoplastic. Gene Transfer Techniques. Green Fluorescent Proteins / genetics. Humans. Male. Mice. Mice, SCID. Oligonucleotide Array Sequence Analysis. Phenotype. Retroviridae / genetics

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  • [Copyright] Copyright 2004 Wiley-Liss, Inc.
  • (PMID = 15937962.001).
  • [ISSN] 0270-4137
  • [Journal-full-title] The Prostate
  • [ISO-abbreviation] Prostate
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / CA96403; United States / NCI NIH HHS / CA / P30 CA68485; United States / NIDDK NIH HHS / DK / P60 DK20593
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Proto-Oncogene Proteins c-myc; 147336-22-9 / Green Fluorescent Proteins
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70. Roy C, Gengler L, Sauer B, Lang H: [Role of contrast enhanced US in the evaluation of renal tumors]. J Radiol; 2008 Nov;89(11 Pt 1):1735-44
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  • [Title] [Role of contrast enhanced US in the evaluation of renal tumors].
  • [Transliterated title] Rôle de l'échographie de contraste dans l'évaluation des tumeurs rénales.
  • PURPOSE: To evaluate the role of contrast enhanced US in the characterization of renal tumors.
  • Eighty-six renal tumors (33 solid, 53 cystic) underwent contrast enhanced US after indeterminate CT/MRI (67 lesions) or US (19 lesions).
  • Diagnosis was achieved in 21 cases.
  • Lesions included: 19 renal cell carcinomas (4 conventional, 14 papillary, 1 tubulocystic), 5 oncocytomas, 3 metastases, 6 pseudomasses, and 53 cystic lesions including 6 malignant tumors.
  • RESULTS: Solid tumors were correctly identified in 100% of cases.
  • Characterization of solid tumors was possible with specificity of 92.9% for papillary carcinoma, 57.1% for clear cell carcinoma, and 100% for oncocytoma.
  • The specificity for distinguishing solid benign from solid malignant tumor was 100% based on the presence of hypoechogenicity relative to normal renal parenchyma on delayed imaging.
  • It is of limited value for large cystic lesions or cystic lesions with extensive wall calcification.
  • CONCLUSION: Contrast enhanced US is easily performed in clinical practice and allows improved characterization of some renal tumors compared to other cross sectional imaging techniques.
  • [MeSH-major] Contrast Media. Kidney Neoplasms / ultrasonography

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  • (PMID = 19106830.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article; Multicenter Study
  • [Publication-country] France
  • [Chemical-registry-number] 0 / Contrast Media
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71. Hervouet E, Godinot C: Mitochondrial disorders in renal tumors. Mitochondrion; 2006 Jun;6(3):105-17
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  • [Title] Mitochondrial disorders in renal tumors.
  • The kidney requiring a very active energy production for its pumping functions has a high mitochondrial activity.
  • Kidney tumors can exist either in relatively benign forms, as for example, in oncocytomas that are crowded with mitochondria or in very aggressive forms such as in clear cell renal carcinomas that exhibit strongly down-regulated mitochondrial activities.
  • In this review, the mitochondrial alterations observed in various forms of renal tumors will be discussed with the aim of understanding how the knowledge of mitochondrial impairment mechanisms could be helpful to develop new anti-cancer strategies.
  • [MeSH-major] Carcinoma, Renal Cell / complications. Gene Expression Regulation, Neoplastic. Kidney Neoplasms / complications. Mitochondria / metabolism. Mitochondrial Diseases / complications

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  • (PMID = 16714150.001).
  • [ISSN] 1567-7249
  • [Journal-full-title] Mitochondrion
  • [ISO-abbreviation] Mitochondrion
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Reactive Oxygen Species
  • [Number-of-references] 120
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72. Casarin A, Martella M, Polli R, Leonardi E, Anesi L, Murgia A: Molecular characterization of large deletions in the von Hippel-Lindau (VHL) gene by quantitative real-time PCR: the hypothesis of an alu-mediated mechanism underlying VHL gene rearrangements. Mol Diagn Ther; 2006;10(4):243-9
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  • INTRODUCTION: Mutations of the von Hippel-Lindau (VHL) gene are responsible for VHL disease.
  • This is a familial autosomal-dominant syndrome, predisposing to the development of benign and malignant tumors, including CNS and retinal hemangioblastomas, pheochromocytomas, and clear cell renal carcinomas.
  • At least 30% of the disease-causing mutations in the VHL gene involve large alterations.
  • [MeSH-major] Alu Elements / genetics. Recombination, Genetic. Sequence Deletion. Von Hippel-Lindau Tumor Suppressor Protein / genetics. von Hippel-Lindau Disease / genetics

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  • [Cites] Blood Cells Mol Dis. 2002 Jan-Feb;28(1):57-62 [11987242.001]
  • [Cites] Blood. 2003 Feb 15;101(4):1591-5 [12393546.001]
  • [Cites] Methods. 2001 Dec;25(4):402-8 [11846609.001]
  • [Cites] Blood. 2003 Aug 1;102(3):1097-9 [12702509.001]
  • [Cites] Science. 2004 Jul 23;305(5683):525-8 [15273396.001]
  • [Cites] Mol Genet Metab. 1999 Jul;67(3):183-93 [10381326.001]
  • [Cites] Medicine (Baltimore). 1997 Nov;76(6):381-91 [9413424.001]
  • [Cites] Blood. 1987 Jul;70(1):293-300 [3593968.001]
  • [Cites] Science. 1993 May 28;260(5112):1317-20 [8493574.001]
  • [Cites] Hum Genet. 1994 Jan;93(1):53-8 [8270255.001]
  • [Cites] Science. 1995 Sep 8;269(5229):1444-6 [7660130.001]
  • [Cites] Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2156-61 [9122164.001]
  • [Cites] Science. 1995 Sep 8;269(5229):1402-6 [7660122.001]
  • [Cites] Nat Genet. 2004 Sep;36(9):949-51 [15286789.001]
  • [Cites] J Assoc Genet Technol. 2004;30(2):41-47 [15345864.001]
  • [Cites] Genes Dev. 1999 Jul 15;13(14 ):1822-33 [10421634.001]
  • [Cites] Hum Mol Genet. 1994 Aug;3(8):1303-8 [7987306.001]
  • [Cites] Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7205-9 [8394013.001]
  • [Cites] Nat Med. 1995 Aug;1(8):822-6 [7585187.001]
  • [Cites] Cancer Res. 1995 Oct 15;55(20):4544-8 [7553625.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12436-41 [10535940.001]
  • [Cites] Hum Mutat. 1998;12 (6):417-23 [9829911.001]
  • [Cites] Mol Cell Biol. 1998 Feb;18(2):732-41 [9447969.001]
  • [Cites] Proc Natl Acad Sci U S A. 1986 Jun;83(11):3875-9 [3012536.001]
  • [Cites] Lab Invest. 2005 Jan;85(1):24-33 [15608663.001]
  • (PMID = 16884328.001).
  • [ISSN] 1177-1062
  • [Journal-full-title] Molecular diagnosis & therapy
  • [ISO-abbreviation] Mol Diagn Ther
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] New Zealand
  • [Chemical-registry-number] EC 2.3.2.27 / Von Hippel-Lindau Tumor Suppressor Protein; EC 6.3.2.- / VHL protein, human
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73. Lin SY, Liu WY, Chen WC, Chen RH: Secondary hypertension due to a renin-secreting juxtaglomerular cell tumor. J Formos Med Assoc; 2010 Mar;109(3):237-40
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  • [Title] Secondary hypertension due to a renin-secreting juxtaglomerular cell tumor.
  • A juxtaglomerular cell tumor (JCT) is a rare, renin-secreting tumor of the kidney and can cause hypertension.
  • JCT is pathologically benign, and resection of the tumor is curative for hypertension.
  • Abdominal computed tomography disclosed a 2 cm solid mass in the left kidney.
  • However, renal vein sampling and captopril test results were equivocal.

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  • [Copyright] 2010 Formosan Medical Association & Elsevier. Published by Elsevier B.V. All rights reserved.
  • (PMID = 20434032.001).
  • [ISSN] 0929-6646
  • [Journal-full-title] Journal of the Formosan Medical Association = Taiwan yi zhi
  • [ISO-abbreviation] J. Formos. Med. Assoc.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Singapore
  • [Chemical-registry-number] EC 3.4.23.15 / Renin
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74. Hes O, Michal M, Kuroda N, Martignoni G, Brunelli M, Lu Y, Adley BP, Alvarado-Cabrero I, Yang XJ: Vimentin reactivity in renal oncocytoma: immunohistochemical study of 234 cases. Arch Pathol Lab Med; 2007 Dec;131(12):1782-8
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  • [Title] Vimentin reactivity in renal oncocytoma: immunohistochemical study of 234 cases.
  • CONTEXT: The expression of vimentin in benign renal oncocytomas has been controversial.
  • However, this is of clinical significance because immunostains may be used in differential diagnosis of renal tumors on limited biopsy specimens.
  • Using different staining and analysis methods, we studied vimentin immunoreactivity in a large series of renal oncocytomas with a special emphasis on the immunoreactivity patterns.
  • OBJECTIVE: Immunohistochemical expression of vimentin has been used in the differential diagnosis of renal epithelial neoplasms.
  • Although typically expressed in most renal cell carcinomas, the immunoreactivity of this intermediate filament in renal oncocytomas has been controversial.
  • DESIGN: We studied vimentin immunoreactivity in a large series of 234 renal oncocytomas using 2 staining methods as well as manual and automated imaging analyses.
  • RESULTS: We found that the focal vimentin immunoreactivity can be seen in most (72.6%) renal oncocytomas with vimentin-positive tumor cells usually found in the edge of a central scar or in small clusters scattered throughout the tumor.
  • Computer-aided imaging analysis using ChromaVision Automatic Cellular Imaging System II confirmed the difference in vimentin immunoreactivity between oncocytoma and other renal neoplasms.
  • CONCLUSIONS: Our study of vimentin immunohistochemistry in a series of renal oncocytomas, which to our knowledge is the largest ever published, showed focal vimentin positivity detected in most oncocytomas.
  • Because the vimentin staining patterns in renal oncocytomas are different from those seen in clear cell or papillary renal cell carcinomas, we consider vimentin staining to be helpful in the differential diagnosis of oncocytoma from other renal tumor mimics.
  • Furthermore, strong vimentin positivity in a renal cell neoplasm does not exclude the diagnosis of renal oncocytoma, particularly in a limited biopsy specimen.
  • [MeSH-major] Adenoma, Oxyphilic / metabolism. Kidney Neoplasms / metabolism. Vimentin / biosynthesis
  • [MeSH-minor] Diagnosis, Differential. Humans. Image Processing, Computer-Assisted. Immunohistochemistry

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  • (PMID = 18081436.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Vimentin
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75. Leung RS, Biswas SV, Duncan M, Rankin S: Imaging features of von Hippel-Lindau disease. Radiographics; 2008 Jan-Feb;28(1):65-79; quiz 323
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  • [Title] Imaging features of von Hippel-Lindau disease.
  • von Hippel-Lindau (VHL) disease is a rare, autosomal dominantly inherited multisystem disorder characterized by development of a variety of benign and malignant tumors.
  • The spectrum of clinical manifestations of the disease is broad and includes retinal and central nervous system hemangioblastomas, endolymphatic sac tumors, renal cysts and tumors, pancreatic cysts and tumors, pheochromocytomas, and epididymal cystadenomas.
  • The most common causes of death in VHL disease patients are renal cell carcinoma and neurologic complications from cerebellar hemangioblastomas.
  • Screening is important because the lesions in VHL disease are treatable; thus, early detection allows use of more conservative therapy and may enhance the patient's length and quality of life.
  • A multidisciplinary team approach is important in screening for VHL disease.
  • [MeSH-major] Diagnostic Imaging / methods. Image Enhancement / methods. Neoplasms / diagnosis. von Hippel-Lindau Disease / diagnosis

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  • (PMID = 18203931.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 28
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76. Gould Rothberg BE, Grooms MC, Dharnidharka VR: Rapid growth of a kidney angiomyolipoma after initiation of oral contraceptive therapy. Obstet Gynecol; 2006 Sep;108(3 Pt 2):734-6
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  • [Title] Rapid growth of a kidney angiomyolipoma after initiation of oral contraceptive therapy.
  • BACKGROUND: Kidney angiomyolipomas are benign but progressive tumors consisting of smooth muscle, fat, and vascular elements, commonly associated with the tuberous sclerosis complex.
  • CONCLUSION: Treating menorrhagia with exogenous hormonal therapy in women with tuberous sclerosis complex should be accompanied by regular renal imaging to reduce the risk of an unanticipated angiomyolipoma-related adverse event.
  • [MeSH-major] Angiomyolipoma / pathology. Contraceptives, Oral / adverse effects. Kidney Neoplasms / pathology. Menorrhagia / drug therapy

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  • (PMID = 17018483.001).
  • [ISSN] 0029-7844
  • [Journal-full-title] Obstetrics and gynecology
  • [ISO-abbreviation] Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral
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77. Tsai CC, Wu WJ, Li CC, Wang CJ, Wu CH, Wu CC: Epithelioid angiomyolipoma of the kidney mimicking renal cell carcinoma: a clinicopathologic analysis of cases and literature review. Kaohsiung J Med Sci; 2009 Mar;25(3):133-40
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  • [Title] Epithelioid angiomyolipoma of the kidney mimicking renal cell carcinoma: a clinicopathologic analysis of cases and literature review.
  • Classical renal angiomyolipoma (AML) is a common tumor that, in most cases, follows a benign course and has clearly defined radiologic and histological characteristics.
  • In all cases, renal lesions seen on computed tomography (CT) were considered as suspicious for renal cell carcinoma (RCC) without tumor extension or metastasis.
  • One of the two patients with definitive tuberous sclerosis complex had a small conventional AML with fat content in the other kidney.
  • Histologically, these tumors can resemble sarcomatoid RCC or high grade RCC.
  • The final diagnosis is established by the presence of perivascular epithelioid cells and immunohistochemistry markers.
  • There was no evidence of local recurrence or metastatic disease found by sonography, CT and magnetic resonance imaging during the follow-up period.
  • Approximately one third of the reported EAMLs show advanced disease; therefore, we recommend that it is important to treat and closely follow-up such cases, similar to that for RCC, because of its malignant potential.
  • [MeSH-major] Angiomyolipoma / diagnosis. Kidney Neoplasms / diagnosis

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  • (PMID = 19419918.001).
  • [ISSN] 1607-551X
  • [Journal-full-title] The Kaohsiung journal of medical sciences
  • [ISO-abbreviation] Kaohsiung J. Med. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] China (Republic : 1949- )
  • [Number-of-references] 70
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78. Hatano K, Fujita S, Tsujimoto Y, Takada T, Honda M, Tsujimoto M, Matsumiya K, Fujioka H: Rare case of the hyaline vascular type of Castleman's disease of the kidney. Int J Urol; 2007 Dec;14(12):1098-100
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  • [Title] Rare case of the hyaline vascular type of Castleman's disease of the kidney.
  • Castleman's disease (CD) is a rare disorder characterized by a benign proliferation of lymphoid tissue.
  • To the best of our knowledge, however, only one case of CD of the kidney has been published in an English report.
  • We herein report a rare case of CD presenting as a left renal tumor.
  • A 70-year-old male was examined by computed tomography for a follow-up for colonic diverticulitis and a left renal mass measuring 2.0 cm in diameter was incidentally found.
  • The patient underwent a left partial nephrectomy for a left renal mass and a histopathological analysis demonstrated the hyaline vascular type of CD.
  • Based on our findings, CD should be included in the differential diagnosis of renal tumors.
  • [MeSH-major] Giant Lymph Node Hyperplasia / diagnosis. Giant Lymph Node Hyperplasia / pathology

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  • (PMID = 18036051.001).
  • [ISSN] 0919-8172
  • [Journal-full-title] International journal of urology : official journal of the Japanese Urological Association
  • [ISO-abbreviation] Int. J. Urol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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79. Mangal N, Sharma VK, Verma N, Agarwal AK, Sharma SP, Aneja S: Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases. J Cytol; 2009 Jul;26(3):97-101
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  • [Title] Ultrasound guided fine needle aspiration cytology in the diagnosis of retroperitoneal masses: A study of 85 cases.
  • BACKGROUND: The diagnosis of retroperitoneal lesions is one of the most difficult areas in surgical pathology.
  • The retroperitoneal space allows both primary and metastatic tumors to grow silently before the appearance of clinical signs and symptoms.
  • Fine needle aspiration cytology has shown promising role in establishing the diagnosis in this region.
  • OBJECTIVES: This study was undertaken to evaluate the reliability of ultrasonography (USG)-guided fine needle aspiration cytology (FNAC) in distinguishing between benign and malignant lesions in the retroperitoneum, and to correlate the diagnosis by cytology of retroperitoneal masses with the results obtained by histology.
  • RESULTS: Out of 85 cases, 32 were of kidney, 27 of lymph nodes, 24 of retroperitoneal soft tissues, and two were of the adrenals.
  • In the kidney, the maximum number of cases were of renal cell carcinoma (12-38%), followed by Wilm's tumor (6-19%), pyonephrosis (5-16%), renal cyst (4), angiomyolipoma (2), cortical pseudotumor (2), and tuberculosis (1).
  • Among the 24 soft tissue tumors in the study, seven (29%) were malignant and 17 (71%) were benign (lipoma being the most common benign neoplasm).
  • Two cases for which the histopathological results were inconsistent with the FNAC diagnoses, were of renal cell carcinoma, which had been diagnosed as renal cysts on cytology.
  • CONCLUSIONS: USG-guided FNAC is an inexpensive, rapid, safe, and accurate procedure for the diagnosis of retroperitoneal masses.

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  • [Cites] Scand J Urol Nephrol. 1974;8(3):223-6 [4428186.001]
  • [Cites] Cancer. 1997 Apr 25;81(2):71-88 [9126135.001]
  • [Cites] Acta Cytol. 1986 Nov-Dec;30(6):671-8 [3466503.001]
  • [Cites] Acta Radiol. 2002 Mar;43(2):230-4 [12010311.001]
  • [Cites] Diagn Cytopathol. 2002 Dec;27(6):354-61 [12451566.001]
  • [Cites] J Postgrad Med. 1991 Apr;37(2):84-7 [1803003.001]
  • [Cites] Acta Cytol. 1988 Jan-Feb;32(1):1-10 [3336946.001]
  • [Cites] J Bone Joint Surg Am. 1982 Oct;64(8):1121-7 [7130225.001]
  • [Cites] Acta Cytol. 1993 Jul-Aug;37(4):477-82 [8392251.001]
  • [Cites] Diagn Cytopathol. 1998 Apr;18(4):297-300 [9557267.001]
  • [Cites] Cytojournal. 2007;4:20 [17973999.001]
  • [Cites] Indian J Pathol Microbiol. 1992 Oct;35(4):333-9 [1344223.001]
  • (PMID = 21938165.001).
  • [ISSN] 0970-9371
  • [Journal-full-title] Journal of cytology
  • [ISO-abbreviation] J Cytol
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3168018
  • [Keywords] NOTNLM ; Ultrasound / fine needle aspiration cytology / retroperitoneum
  •  go-up   go-down


80. Smith JC, Boone BE, Opalenik SR, Williams SM, Russell SB: Gene profiling of keloid fibroblasts shows altered expression in multiple fibrosis-associated pathways. J Invest Dermatol; 2008 May;128(5):1298-310
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  • Keloids are benign tumors of the dermis that form during a protracted wound healing process.
  • The key alteration(s) responsible for keloid formation has not been identified and there is no satisfactory treatment for this disorder.

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  • [Cites] J Endocrinol. 2002 Oct;175(1):19-31 [12379487.001]
  • [Cites] Curr Opin Rheumatol. 2002 Nov;14(6):681-5 [12410091.001]
  • [Cites] Bioinformatics. 2002 Nov;18(11):1454-61 [12424116.001]
  • [Cites] Bioinformatics. 2003 Jan 22;19(2):185-93 [12538238.001]
  • [Cites] Wound Repair Regen. 2006 Jul-Aug;14(4):463-70 [16939575.001]
  • [Cites] Arthritis Rheum. 2006 Sep;54(9):3001-10 [16947625.001]
  • [Cites] Am J Pathol. 2006 Nov;169(5):1633-42 [17071587.001]
  • [Cites] J Invest Dermatol. 2007 Jan;127(1):98-105 [17024100.001]
  • [Cites] Cancer Res. 2007 Jan 1;67(1):75-84 [17210685.001]
  • [Cites] J Invest Dermatol. 1997 Mar;108(3):285-9 [9036926.001]
  • [Cites] Arch Dermatol. 1998 Aug;134(8):963-7 [9722726.001]
  • [Cites] Semin Respir Infect. 1998 Sep;13(3):166-73 [9764947.001]
  • [Cites] Wound Repair Regen. 1998 Jan-Feb;6(1):58-64 [9776851.001]
  • [Cites] Am J Pathol. 1999 Mar;154(3):883-9 [10079266.001]
  • [Cites] J Invest Dermatol. 1999 May;112(5):706-10 [10233760.001]
  • [Cites] Arthritis Rheum. 1999 Jul;42(7):1451-7 [10403273.001]
  • [Cites] Plast Reconstr Surg. 1999 Oct;104(5):1435-58 [10513931.001]
  • [Cites] J Allergy Clin Immunol. 1999 Oct;104(4 Pt 1):723-42 [10518815.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Oct 12;96(21):11776-81 [10518526.001]
  • [Cites] Am J Pathol. 2005 Feb;166(2):399-407 [15681824.001]
  • [Cites] Sci STKE. 2005 Feb 15;2005(271):cm1 [15713948.001]
  • [Cites] J Biol. 2005;4(1):2 [15720723.001]
  • [Cites] J Invest Dermatol. 2005 Apr;124(4):704-13 [15816827.001]
  • [Cites] Acta Derm Venereol. 2005;85(3):216-20 [16040405.001]
  • [Cites] J Pharmacol Exp Ther. 2000 Mar;292(3):988-94 [10688614.001]
  • [Cites] Cytokine Growth Factor Rev. 2000 Mar-Jun;11(1-2):103-14 [10708958.001]
  • [Cites] J Invest Dermatol. 2000 May;114(5):953-9 [10771477.001]
  • [Cites] Wound Repair Regen. 2000 Sep-Oct;8(5):371-82 [11115149.001]
  • [Cites] Am J Physiol Cell Physiol. 2003 Apr;284(4):C860-9 [12620890.001]
  • [Cites] J Exp Med. 2003 Mar 17;197(6):687-701 [12642601.001]
  • [Cites] Am J Pathol. 2003 May;162(5):1393-7 [12707021.001]
  • [Cites] Environ Health Perspect. 2003 Jun;111(8):1037-54 [12826476.001]
  • [Cites] Curr Pharm Des. 2003;9(23):1905-17 [12871194.001]
  • [Cites] Arthritis Rheum. 2003 Aug;48(8):2246-55 [12905479.001]
  • [Cites] Kidney Int Suppl. 2003 Nov;(87):S99-104 [14531781.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12319-24 [14530402.001]
  • [Cites] Br J Pharmacol. 2003 Dec;140(7):1292-302 [14581180.001]
  • [Cites] Hum Mol Genet. 2003 Dec 15;12(24):3259-67 [14570706.001]
  • [Cites] Nat Genet. 2004 Apr;36(4):417-22 [15034581.001]
  • [Cites] Genes Chromosomes Cancer. 2004 Jul;40(3):204-17 [15139000.001]
  • [Cites] J Invest Dermatol. 2004 May;122(5):1126-32 [15140214.001]
  • [Cites] Ann Plast Surg. 2004 Jun;52(6):605-8 [15166997.001]
  • [Cites] Genet Epidemiol. 2004 Sep;27(2):162-72 [15305332.001]
  • [Cites] J Cell Physiol. 1978 Nov;97(2):221-9 [701387.001]
  • [Cites] Coll Relat Res. 1983;3(1):13-23 [6301749.001]
  • [Cites] J Am Acad Dermatol. 1984 Jun;10(6):986-8 [6736343.001]
  • [Cites] Proc Natl Acad Sci U S A. 1988 Jan;85(2):587-91 [3422443.001]
  • [Cites] J Biol Chem. 1989 Aug 15;264(23):13730-5 [2760040.001]
  • [Cites] Science. 1990 Sep 14;249(4974):1266-72 [2119054.001]
  • [Cites] J Biol Chem. 1992 May 5;267(13):9014-20 [1577738.001]
  • [Cites] J Clin Immunol. 1992 Jul;12(4):300-8 [1512303.001]
  • [Cites] J Invest Dermatol. 1995 Feb;104(2):241-5 [7829880.001]
  • [Cites] Growth Factors. 1994;11(3):205-13 [7734146.001]
  • [Cites] Hypertension. 1995 Dec;26(6 Pt 1):858-62 [7490140.001]
  • [Cites] J Invest Dermatol. 1996 Apr;106(4):729-33 [8618012.001]
  • [Cites] Oncogene. 2005 Aug 29;24(37):5764-74 [16123809.001]
  • [Cites] J Clin Endocrinol Metab. 2005 Sep;90(9):5349-55 [15972578.001]
  • [Cites] Wound Repair Regen. 2005 Sep-Oct;13(5):491-7 [16176457.001]
  • [Cites] Genes Cells. 2005 Nov;10(11):1081-91 [16236136.001]
  • [Cites] Nat Rev Cancer. 2006 Feb;6(2):107-16 [16491070.001]
  • [Cites] Int J Mol Med. 2006 Apr;17(4):681-5 [16525728.001]
  • [Cites] Br J Cancer. 2006 Mar 27;94(6):922-7 [16523202.001]
  • [Cites] Arch Dermatol Res. 2006 Apr;297(10):433-8 [16528552.001]
  • [Cites] Bioessays. 2006 May;28(5):445-8 [16615131.001]
  • [Cites] Oncogene. 2006 Jul 6;25(29):4116-21 [16491118.001]
  • [Cites] Acta Derm Venereol. 2006;86(4):300-7 [16874413.001]
  • [Cites] Arch Dermatol. 2001 Nov;137(11):1429-34 [11708945.001]
  • [Cites] J Immunol. 2001 Dec 15;167(12):7126-33 [11739535.001]
  • [Cites] Am J Physiol Renal Physiol. 2002 Mar;282(3):F431-41 [11832423.001]
  • [Cites] J Biol Chem. 2002 May 24;277(21):18860-7 [11886859.001]
  • [Cites] Oncogene. 2002 May 16;21(22):3659-62 [12032868.001]
  • [Cites] Fertil Steril. 2002 Jul;78(1):114-21 [12095500.001]
  • [Cites] Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12877-82 [12297622.001]
  • (PMID = 17989729.001).
  • [ISSN] 1523-1747
  • [Journal-full-title] The Journal of investigative dermatology
  • [ISO-abbreviation] J. Invest. Dermatol.
  • [Language] ENG
  • [Grant] United States / NIAMS NIH HHS / AR / R03 AR048938-01; United States / NIAMS NIH HHS / AR / AR041943-100031; United States / NIAMS NIH HHS / AR / AR052241-01; United States / NIDCR NIH HHS / DE / P50 DE010595-08; United States / NIAMS NIH HHS / AR / F33AR052241; United States / NIDCR NIH HHS / DE / P50 DE010595; United States / NIDCR NIH HHS / DE / DE010595-08; United States / NIAMS NIH HHS / AR / P30 AR041943-100031; United States / NIAMS NIH HHS / AR / R03AR048938; United States / NIAMS NIH HHS / AR / F33 AR052241-01; United States / NIAMS NIH HHS / AR / AR048938-01; United States / NIDCR NIH HHS / DE / P50DE10595; United States / NIAMS NIH HHS / AR / P30AR041943; United States / NIAMS NIH HHS / AR / R03 AR048938; United States / NIAMS NIH HHS / AR / P30 AR041943; United States / NIAMS NIH HHS / AR / F33 AR052241
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS231166; NLM/ PMC2933038
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81. Bonsib SM, Pei Y: The non-neoplastic kidney in tumor nephrectomy specimens: what can it show and what is important? Adv Anat Pathol; 2010 Jul;17(4):235-50
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  • [Title] The non-neoplastic kidney in tumor nephrectomy specimens: what can it show and what is important?
  • In the presence of a normal contralateral kidney, such as in a renal transplant donor or child with Wilms tumor, it is a benign procedure without deleterious consequences on the remaining kidney.
  • However, many adults and some children postnephrectomy will develop chronic kidney disease.
  • The non-neoplastic kidney in tumor resections may harbor a large number of developmental and acquired diseases predictive of this outcome or that convey other medically significant information.
  • Examination of the non-neoplastic kidney is a fertile opportunity to identify these unsuspected conditions that may ultimately dictate the subsequent clinical course and influence the medical care provided.
  • [MeSH-major] Kidney / pathology. Kidney Diseases / etiology. Kidney Neoplasms / surgery. Nephrectomy / adverse effects
  • [MeSH-minor] Adult. Arteriosclerosis / complications. Child. Chronic Disease. Diabetes Complications / complications. Diabetes Complications / pathology. Humans. Kidney Diseases, Cystic / etiology. Kidney Diseases, Cystic / pathology. Lymphangiogenesis. Nephrosclerosis / etiology. Nephrosclerosis / pathology. Wilms Tumor / pathology. Wilms Tumor / surgery

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  • [CommentIn] Adv Anat Pathol. 2011 Mar;18(2):173; author reply 174 [21326015.001]
  • (PMID = 20574169.001).
  • [ISSN] 1533-4031
  • [Journal-full-title] Advances in anatomic pathology
  • [ISO-abbreviation] Adv Anat Pathol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 134
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82. Jones NM, Kiely EM: Retroperitoneal teratomas--potential for surgical misadventure. J Pediatr Surg; 2008 Jan;43(1):184-6; discussion 187
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  • BACKGROUND: Retroperitoneal teratoma (RPT) is a relatively uncommon tumor in children.
  • RESULTS: Four of the 6 patients were girls, and 5 were younger than 6 months at diagnosis.
  • All of the tumors enveloped and displaced the aorta and vena cava, 1 involved the stomach wall, 2 others displaced the renal vessels, and 1 the portal vein.
  • All the tumors were benign, but 1 recurred.
  • Despite their benign nature, the lesions can attenuate and surround major vessels, making resection difficult.
  • Ligation of major vessels when necessary is tolerated well and may be required for complete tumor excision.
  • [MeSH-major] Neoplasm Invasiveness / pathology. Neoplasm Recurrence, Local / pathology. Retroperitoneal Neoplasms / surgery. Teratoma / surgery. Vena Cava, Inferior / pathology
  • [MeSH-minor] Biopsy, Needle. Child. Female. Follow-Up Studies. Great Britain. Humans. Immunohistochemistry. Infant. Infant, Newborn. Laparotomy / methods. Male. Neoplasm Staging. Retrospective Studies. Risk Assessment. Treatment Outcome

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  • (PMID = 18206479.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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83. Gerszten PC, Novotny J Jr, Quader M, Dewald VC, Flickinger JC: Prospective evaluation of a dedicated spine radiosurgery program using the Elekta Synergy S system. J Neurosurg; 2010 Dec;113 Suppl:236-41
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  • The most common histological types for the metastatic lesions (136 cases total) were breast, lung, sarcomas, and renal cells.
  • The most common benign tumors (30 cases total) included 10 schwannomas, 5 neurofibromas, and 5 meningiomas.
  • RESULTS: The prescribed dose to the gross tumor volume, delivered in a single fraction, ranged from 12 to 20 Gy (mean 16 Gy) in this cohort.
  • The gross tumor volumes ranged from 1.2 to 491.7 cm(3) (mean 39.2 cm(3)).
  • [MeSH-major] Radiosurgery / instrumentation. Spinal Neoplasms / surgery. Spine / surgery

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  • (PMID = 21121807.001).
  • [ISSN] 1933-0693
  • [Journal-full-title] Journal of neurosurgery
  • [ISO-abbreviation] J. Neurosurg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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84. Anastasiadis A, Dimitriadis G, Radopoulos D: Incidental giant renal oncocytoma: a case report. J Med Case Rep; 2010;4:358
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  • [Title] Incidental giant renal oncocytoma: a case report.
  • INTRODUCTION: Large renal oncocytomas are not very rare entities.
  • The tumor was incidentally diagnosed and, based on the preoperative clinical and radiographic findings, was therefore considered to be a renal cell carcinoma.
  • CASE PRESENTATION: A 48-year-old Caucasian diabetic man had an abdominal ultrasound for chronic abdominal discomfort, which revealed a large mass on the left kidney.
  • A magnetic resonance imaging scan was performed with no evidence of renal vein or caval thrombus or embolus.
  • A radical nephrectomy was performed through a left flank intercostal incision and the pathology diagnosed renal oncocytoma.
  • CONCLUSION: Several reports have characterised this essentially benign renal histiotype, which represents 5% to 7% of all solid renal masses.
  • Unfortunately, most renal oncocytomas cannot be differentiated from malignant renal cell carcinomas by clinical or radiographic criteria.
  • Central stellate scar and a spoke-wheel pattern of feeding arteries are unreliable diagnostic signs and are of poor predictive value.
  • These tumors are treated operatively with radical or partial nephrectomy or thermal ablation, depending on the clinical circumstances.
  • We report on, to the best of our knowledge, the fourth largest lesion of this type of renal pathology.

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  • (PMID = 21059248.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2990760
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85. Merritt JL 2nd, Davis DM, Pittelkow MR, Babovic-Vuksanovic D: Extensive acrochordons and pancreatic islet-cell tumors in tuberous sclerosis associated with TSC2 mutations. Am J Med Genet A; 2006 Aug 1;140(15):1669-72
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  • [Title] Extensive acrochordons and pancreatic islet-cell tumors in tuberous sclerosis associated with TSC2 mutations.
  • Acrochordons are frequently encountered benign skin lesions that may occasionally represent underlying pathology.
  • Pancreatic islet-cell tumors are rare neoplasms and few cases have been described in patients with tuberous sclerosis complex (TSC).
  • A 39-year-old man presenting in acute renal failure was referred to us for further diagnostic evaluation of coincidentally noted dysmorphic features.
  • The diagnosis was confirmed by disclosure of mutation in the TSC2 gene.
  • Further evaluation revealed pancreatic islet cell tumors.
  • Additionally, mutations in TSC2 gene may be a risk factor for developing pancreatic islet-cell tumors.
  • [MeSH-major] Adenoma, Islet Cell / genetics. Adenoma, Islet Cell / pathology. Mutation. Pancreatic Neoplasms / genetics. Pancreatic Neoplasms / pathology. Skin Diseases / genetics. Tuberous Sclerosis / genetics. Tumor Suppressor Proteins / genetics
  • [MeSH-minor] Adult. Female. Humans. Male. Pedigree. Renal Insufficiency / diagnosis. Renal Insufficiency / genetics


86. Astigueta JC, Abad MA, Pow-Sang MR, Morante C, Meza L, Destefano V, Dyer R: Epithelioid angiomyolipoma: a rare variant of renal angiomyolipoma. Arch Esp Urol; 2009 Jul;62(6):493-7
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  • [Title] Epithelioid angiomyolipoma: a rare variant of renal angiomyolipoma.
  • OBJECTIVE: We present a case of primary renal epithelioid angiomyolipoma, its association with tuberous sclerosis and review the literature.
  • CT scan of the abdomen showed the presence of a left renal tumor.
  • Pathologic study of the specimen showed primary renal epithelioid angiomyolipoma, corroborated by immunohistochemistry staining.
  • CONCLUSIONS: Renal angiomyolipoma is an uncommon benign tumor, representing a challenge for clinical and pathological diagnosis.
  • [MeSH-major] Angiomyolipoma / pathology. Kidney Neoplasms / pathology

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  • (PMID = 19736381.001).
  • [ISSN] 1576-8260
  • [Journal-full-title] Archivos españoles de urología
  • [ISO-abbreviation] Arch. Esp. Urol.
  • [Language] eng; spa
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Spain
  • [Number-of-references] 15
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87. Ficarra V, Brunelli M, Cheng L, Kirkali Z, Lopez-Beltran A, Martignoni G, Montironi R, Novara G, Van Poppel H: Prognostic and therapeutic impact of the histopathologic definition of parenchymal epithelial renal tumors. Eur Urol; 2010 Nov;58(5):655-68
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  • [Title] Prognostic and therapeutic impact of the histopathologic definition of parenchymal epithelial renal tumors.
  • CONTEXT: In the last few years, the treatment of renal cell carcinoma (RCC) has progressed significantly, and some histopathologic issues have become important for selection and follow-up after medical and surgical therapies.
  • OBJECTIVE: The aim of this collaborative article is to review the most recent literature on the role of traditional histopathologic features obtained from renal core biopsy or nephrectomy specimens in the management of confined, locally advanced, and metastatic RCC.
  • Multiple free-text searches were performed for the following items: renal cell carcinoma, clear cell, papillary, chromophobe, histologic* subtype*, histotype*, nuclear grade*, necrosis, sarcomatoid differentiation, biopsy, molecular marker*, and cytogenetic marker*.
  • EVIDENCE SYNTHESIS: Core needle biopsies can provide important information that is useful to avoid the overtreatment of benign tumors and to help plan watchful waiting or minimally invasive treatments in selected patients.
  • Tumor histotype is fundamental in the pathologic report.
  • CONCLUSIONS: The histopathologic definition of parenchymal epithelial renal tumors is fundamental to plan the management and follow-up of patients with locally confined, locally advanced, and metastatic RCC.
  • [MeSH-major] Carcinoma, Renal Cell / epidemiology. Carcinoma, Renal Cell / pathology. Evidence-Based Medicine. Kidney Neoplasms / epidemiology. Kidney Neoplasms / pathology

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  • [Copyright] Copyright © 2010 European Association of Urology. Published by Elsevier B.V. All rights reserved.
  • [CommentIn] Eur Urol. 2010 Nov;58(5):669-70 [20846782.001]
  • (PMID = 20727666.001).
  • [ISSN] 1873-7560
  • [Journal-full-title] European urology
  • [ISO-abbreviation] Eur. Urol.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Switzerland
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88. Cheung MC, Lee FC, Chu SM, Leung YL, Wong BB, Ho KL, Tam PC: Laparoscopic nephrectomy: an early experience at Queen Mary Hospital. Hong Kong Med J; 2005 Feb;11(1):7-11
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  • RESULTS: Laparoscopic nephrectomy was performed for 21 solid renal masses, five transitional cell carcinomas, and 14 non-functioning kidneys.
  • The mean diameter of the solid renal tumour was 4.1 cm and the surgical margins of all resected specimen for malignant tumours were negative.
  • CONCLUSION: Laparoscopic nephrectomy is a safe and efficacious approach for resection of benign non-functioning kidneys and malignant renal tumours.

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  • (PMID = 15687510.001).
  • [ISSN] 1024-2708
  • [Journal-full-title] Hong Kong medical journal = Xianggang yi xue za zhi
  • [ISO-abbreviation] Hong Kong Med J
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] China
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89. Graser A, Becker CR, Staehler M, Clevert DA, Macari M, Arndt N, Nikolaou K, Sommer W, Stief C, Reiser MF, Johnson TR: Single-phase dual-energy CT allows for characterization of renal masses as benign or malignant. Invest Radiol; 2010 Jul;45(7):399-405
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  • [Title] Single-phase dual-energy CT allows for characterization of renal masses as benign or malignant.
  • PURPOSE: To evaluate the diagnostic accuracy of dual-energy CT (DECT) in renal mass characterization using a single-phase acquisition.
  • MATERIALS AND METHODS: A total of 202 patients (148 males, 54 females; 63 +/- 13 years) with ultrasound-based suspicion of a renal mass underwent unenhanced single energy and nephrographic phase DECT on a dual source scanner (Siemens Somatom Definition Dual Source, n = 174; Somatom Definition Flash, n = 28).
  • Using solely the DE acquisition including virtual nonenhanced (VNE) and color coded iodine images that enable direct visualization of iodine, masses were characterized as benign or malignant.
  • RESULTS: Of the 202 patients, 115 (56.9%) underwent surgical resection of renal masses.
  • Histopathology showed malignancy in 99 and benign tumors in 18 patients, in 48 patients (23.7%), follow-up imaging showed size stability of lesions diagnosed as benign, and 37 patients (18.3%) had no mass.
  • CONCLUSION: DECT allows for fast and accurate characterization of renal masses in a single-phase acquisition.
  • [MeSH-major] Kidney Neoplasms / radiography. Radiography, Dual-Energy Scanned Projection / methods. Tomography, X-Ray Computed / methods
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Male. Radiographic Image Enhancement / methods. Reproducibility of Results. Sensitivity and Specificity

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  • (PMID = 20498609.001).
  • [ISSN] 1536-0210
  • [Journal-full-title] Investigative radiology
  • [ISO-abbreviation] Invest Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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90. Turbiner J, Amin MB, Humphrey PA, Srigley JR, De Leval L, Radhakrishnan A, Oliva E: Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term. Am J Surg Pathol; 2007 Apr;31(4):489-500
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  • [Title] Cystic nephroma and mixed epithelial and stromal tumor of kidney: a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor (REST) as a unifying term.
  • Cystic nephroma (CN) and mixed epithelial and stromal tumor (MEST) are rare benign renal neoplasms that have overlapping clinical and morphologic features, including predominance in middle-aged women, variably cystic architecture, eosinophilic cells, and hobnail cells lining the cysts and ovarian-type stroma.
  • The aim of this study was to analyze and compare the histologic features and immunohistochemical profile of these tumors.
  • Twenty tumors were diagnosed as CNs, 18 in women and 2 in men, their age ranged from 24 to 63 (mean 48; median 50) years.
  • Fourteen tumors were diagnosed as MESTs, all in women, their age ranged from 26 to 84 (mean 52; median 51) years.
  • Histologically, all tumors were well-circumscribed except for one MEST.
  • The epithelial component ranged from flat to cuboidal to hobnail cells in both types of tumors.
  • Follow-up in both categories of tumors (mean 3.2 y, median 3 y for CNs and mean 2.5 y, median of 2 y for MESTs) showed no evidence of recurrence or metastases in keeping with their benign nature.
  • The presence of ovarian-type stroma and müllerian related immunohistochemical markers raises the possibility that these tumors may originate from müllerian remnants misplaced during embryogenesis.
  • On the basis of detailed morphologic analysis of this series of CN and MEST, we propose a unifying term of "renal epithelial and stromal tumor" (REST) to encompass the spectrum of findings observed in these tumors at least until new molecular studies can prove or disprove this challenging hypothesis.
  • [MeSH-major] Kidney Neoplasms / classification. Kidney Neoplasms / pathology. Neoplasms, Glandular and Epithelial / classification. Neoplasms, Glandular and Epithelial / pathology. Nephroma, Mesoblastic / classification. Nephroma, Mesoblastic / pathology

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  • (PMID = 17414095.001).
  • [ISSN] 0147-5185
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Receptors, Estrogen; 0 / Receptors, Progesterone
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91. Zarate YA, Mena R, Martin LJ, Steele P, Tinkle BT, Hopkin RJ: Experience with hemihyperplasia and Beckwith-Wiedemann syndrome surveillance protocol. Am J Med Genet A; 2009 Aug;149A(8):1691-7
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  • Multiple surveillance protocols have been proposed to detect the most commonly reported tumor types Wilms tumor and hepatoblastoma.
  • Two patients had well documented cases of tumors/tumor precursor (2/63:3.2%) detected by ultrasound images.
  • In conclusion, ultrasound surveillance detected renal and liver pathology including benign and malignant lesions.
  • [MeSH-minor] Age Distribution. Case-Control Studies. Child. Child, Preschool. Confidence Intervals. Humans. Kidney / abnormalities. Kidney / pathology. Kidney / ultrasonography. Liver / abnormalities. Liver / pathology. Liver / ultrasonography. Patient Compliance. Phenotype. alpha-Fetoproteins / metabolism

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  • [Copyright] 2009 Wiley-Liss, Inc.
  • (PMID = 19610116.001).
  • [ISSN] 1552-4833
  • [Journal-full-title] American journal of medical genetics. Part A
  • [ISO-abbreviation] Am. J. Med. Genet. A
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / alpha-Fetoproteins
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92. Bonsib SM: Renal cystic diseases and renal neoplasms: a mini-review. Clin J Am Soc Nephrol; 2009 Dec;4(12):1998-2007
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  • [Title] Renal cystic diseases and renal neoplasms: a mini-review.
  • The past two decades have witnessed recognition of several new types of renal cell carcinoma, each with distinct cytogenetic abnormalities.
  • Included are several genetic and acquired cystic kidney diseases associated with development of renal cell carcinoma, the topic of this review.
  • The risk in patients with autosomal dominant polycystic kidney disease is not accurately known but may be slightly increased.
  • The risk for patients with von Hippel-Lindau disease is substantial, and death from renal cancer is common.
  • For patients with tuberous sclerosis complex, the challenge is recognition of the occasional malignancy arising in a field of many benign tumors.
  • Patients with end-stage kidney disease and acquired cystic kidney disease may develop a variety of renal cell carcinoma types.
  • Progress in understanding the molecular basis of renal cyst formation and neoplastic disease has fostered development of targeted therapies that now hold promise for a group of neoplasms whose cure was traditionally dependent on surgical approaches.
  • [MeSH-major] Carcinoma, Renal Cell. Kidney Diseases, Cystic. Kidney Neoplasms

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  • (PMID = 19875768.001).
  • [ISSN] 1555-905X
  • [Journal-full-title] Clinical journal of the American Society of Nephrology : CJASN
  • [ISO-abbreviation] Clin J Am Soc Nephrol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 112
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93. Kümmerlin IP, ten Kate FJ, Wijkstra H, Zwinderman A, de la Rosette JJ, Laguna MP: A decade of surgically removed small renal masses in the Netherlands: characteristics and trends in type of surgery and pathologic reporting. J Endourol; 2010 Oct;24(10):1675-9
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  • [Title] A decade of surgically removed small renal masses in the Netherlands: characteristics and trends in type of surgery and pathologic reporting.
  • PURPOSE: To assess nationwide the pathologic characteristics and trends in type of surgery and pathologic reporting in surgically managed renal tumors ≤ 4 cm.
  • MATERIALS AND METHODS: A review of all pathologic reports of primary small renal masses operated on in the Netherlands during the period 1995 to 2005 was performed.
  • Tumors were stratified into three groups: ≤ 2, 2.1 to 3.0, and 3.1 to 4.0 cm.
  • Age, sex, type of operation, and tumor pathology were analyzed.
  • For renal-cell carcinomas, grade (3-tiers Fuhrman) and stage (2002 Tumor, Node, Metastasis) were assessed.
  • RESULTS: Of all operated primary kidney tumors, 25.3% were ≤ 4.0 cm.
  • Only 7.5% were benign tumors, and 9.8% were locally advanced (≥ T₃).
  • Tumors ≤ 3.0 cm were more likely to be benign (P = 0.006) and of lower stage (P ≤ 0.001) than tumors of 3.1 to 4 cm.
  • CONCLUSIONS: A quarter of all the operated primary kidney tumors were ≤ 4 cm.
  • Smaller tumors were more likely to be benign and of lower stage.

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  • (PMID = 20818987.001).
  • [ISSN] 1557-900X
  • [Journal-full-title] Journal of endourology
  • [ISO-abbreviation] J. Endourol.
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
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94. Talmon GA: Pure erythropoiesis in clear cell renal cell carcinoma. Int J Surg Pathol; 2010 Dec;18(6):544-6
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  • [Title] Pure erythropoiesis in clear cell renal cell carcinoma.
  • Extramedullary hematopoiesis (EMH) is a phenomenon in which benign immature hematopoietic cells are found in sites other than the bone marrow.
  • Although usually associated with an underlying hematologic abnormality such as myelofibrosis, it can be found in some physiologic states or occasionally within solid tumors.
  • Presented here is the second reported case of EMH occurring in a low-grade clear cell renal cell carcinoma in a patient without evidence of hematologic disease.
  • It is possible that this finding is related to erythropoietin secretion by the tumor and not hematologic malignancy.
  • [MeSH-major] Carcinoma, Renal Cell / physiopathology. Erythropoiesis. Hematopoiesis, Extramedullary. Kidney Neoplasms / physiopathology


95. Ahmed Z, Azad NS, Bhurgari Y, Ahmed R, Kayani N, Pervez S, Hasan S: Significance of immunohistochemistry in accurate characterization of malignant tumors. J Ayub Med Coll Abbottabad; 2006 Apr-Jun;18(2):38-43
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  • [Title] Significance of immunohistochemistry in accurate characterization of malignant tumors.
  • BACKGROUND: To determine in a large series of surgical biopsies the role and significance of immunohistochemistry in the adequate and accurate characterization of malignant tumors.
  • 4726 neoplasms (72.33%) were malignant, and 1808 (27.67%) were benign.
  • Immunohistochemistry was performed on 29.49% of malignant tumors, and 4.97% of benign tumors.
  • Immunos were performed on only 2.82% of routine squamous cell carcinomas and adenocarcinomas of various organs, and in only 1.9% of infiltrating breast carcinomas, the commonest malignant tumors in females.
  • In contrast, immunos were performed on 97.12% of non-Hodgkin's lymphomas, 97.94% of Hodgkin's lymphomas, 98.09% of malignant spindle cell neoplasms, 87.96% of small round blue cell tumors of childhood, 87.30% of neuroendocrine neoplasms, and 84.37% cases of malignant melanomas.
  • In addition, immunos were performed on all cases of malignant undifferentiated neoplasms and were able to resolve the issue in over 89% of such cases.
  • Immunos were also performed on 54.74% of metastatic tumors.
  • 96.50% of lymph node tumors, followed by CNS and renal neoplasms with 33.01% and 25.92% respectively.
  • [MeSH-major] Immunoenzyme Techniques. Neoplasms / pathology

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  • (PMID = 16977812.001).
  • [ISSN] 1025-9589
  • [Journal-full-title] Journal of Ayub Medical College, Abbottabad : JAMC
  • [ISO-abbreviation] J Ayub Med Coll Abbottabad
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Pakistan
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96. Opocher G, Schiavi F, Iacobone M, Toniato A, Sattarova S, Erlic Z, Martella M, Mian C, Merante Boschin I, Zambonin L, De Lazzari P, Murgia A, Pelizzo MR, Favia G, Mantero F: Familial nonsyndromic pheochromocytoma. Ann N Y Acad Sci; 2006 Aug;1073:149-55
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  • The proband of family 2 is a female who had a 5-cm benign adrenal pheochromocytoma at the age of 34 years, while her cousin (maternal branch) had a monolateral pheochromocytoma at the age of 42 years.
  • No other tumors had been reported in either family.
  • Several other tumors were recorded in this family, including laryngeal cancer, leukemia, and a case of medullary thyroid carcinoma (MTC) in one brother.
  • Her brother had a monolateral benign pheochromocytoma.
  • The proband also had a melanoma and bilateral renal cysts.
  • Although other molecular mechanisms, such as particular variants in untranslated regions or partial gene deletions, cannot be ruled out, we think finding families with nonsyndromic pheochromocytoma without any RET, VHL, SDHB, SDHC, SDHD, or EGLN3 mutation may argue in favor of the presence of other pheochromocytoma susceptibility genes.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Pheochromocytoma / genetics
  • [MeSH-minor] Genetic Predisposition to Disease. Humans. Proto-Oncogene Proteins c-ret / genetics. Succinate Dehydrogenase / genetics. Von Hippel-Lindau Tumor Suppressor Protein / genetics

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  • (PMID = 17102081.001).
  • [ISSN] 0077-8923
  • [Journal-full-title] Annals of the New York Academy of Sciences
  • [ISO-abbreviation] Ann. N. Y. Acad. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 1.3.99.1 / Succinate Dehydrogenase; EC 2.7.10.1 / Proto-Oncogene Proteins c-ret; EC 2.7.10.1 / RET protein, human; EC 6.3.2.19 / VHL protein, human; EC 6.3.2.19 / Von Hippel-Lindau Tumor Suppressor Protein
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97. Gautam G, Zorn KC: The current role of renal biopsy in the management of localized renal tumors. Indian J Urol; 2009 Oct-Dec;25(4):494-8
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  • [Title] The current role of renal biopsy in the management of localized renal tumors.
  • Introduction : In the current era of nephron-sparing surgery (NSS) for localized tumors, pretreatment tissue biopsy is being revisited and re-evaluated.
  • Whether a renal biopsy can supplement imaging investigations to change patient management is a subject of current research.
  • Results : Preoperative renal biopsy has been utilized to effectively distinguish between benign and malignant tumors localized to the kidney with minimal additional morbidity attributable to the procedure.
  • Tissue diagnosis can also potentially grade renal tumors and uncover unusual malignancies.
  • Although its acceptance remains limited, with fear of false negative results, bleeding and tumor seeding, its ability to influence management decisions has been demonstrated in literature.
  • Conclusions : The role of preoperative renal biopsy for localized renal tumors is likely to increase rapidly in the coming times.

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  • [Cites] Hum Pathol. 2005 Dec;36(12):1309-15 [16311125.001]
  • [Cites] BJU Int. 2006 May;97(5):946-9 [16643475.001]
  • [Cites] Acta Cytol. 2004 Nov-Dec;48(6):843-8 [15581171.001]
  • [Cites] J Urol. 1999 May;161(5):1470-4 [10210375.001]
  • [Cites] JAMA. 1999 May 5;281(17):1628-31 [10235157.001]
  • [Cites] Acta Cytol. 1998 Nov-Dec;42(6):1444-6 [9850658.001]
  • [Cites] Urology. 1997 Jul;50(1):25-9 [9218014.001]
  • [Cites] AJR Am J Roentgenol. 1993 Dec;161(6):1303-5 [8249747.001]
  • [Cites] Radiology. 1993 Mar;186(3):693-6 [8430176.001]
  • [Cites] Acta Cytol. 1991 Nov-Dec;35(6):742-5 [1950327.001]
  • [Cites] Cancer. 1988 Apr 15;61(8):1639-51 [3349424.001]
  • [Cites] J Urol. 1986 Dec;136(6):1292-3 [3773108.001]
  • [Cites] J Urol. 1986 Aug;136(2):446-8 [3735515.001]
  • [Cites] J Urol. 2003 Jan;169(1):71-4 [12478106.001]
  • [Cites] Arch Pathol Lab Med. 2002 Apr;126(4):478-80 [11900578.001]
  • [Cites] J Urol. 2002 Jan;167(1):57-60 [11743275.001]
  • [Cites] Diagn Cytopathol. 2000 Oct;23(4):279-83 [11002372.001]
  • [Cites] Acta Cytol. 2000 May-Jun;44(3):380-4 [10833995.001]
  • [Cites] Diagn Cytopathol. 2000 Apr;22(4):223-6 [10787141.001]
  • [Cites] BJU Int. 2000 Jan;85(1):14-8 [10619937.001]
  • [Cites] J Urol. 1985 Dec;134(6):1094-6 [4057398.001]
  • [Cites] Am J Surg Pathol. 1982 Oct;6(7):655-63 [7180965.001]
  • [Cites] Scand J Urol Nephrol. 1981;15(3):269-72 [7323750.001]
  • [Cites] J Urol. 2003 Dec;170(6 Pt 1):2217-20 [14634382.001]
  • [Cites] J Urol. 2004 May;171(5):1802-5 [15076280.001]
  • [Cites] Clin Radiol. 2004 Mar;59(3):262-7 [15037139.001]
  • [Cites] Urology. 2003 Nov;62(5):827-30 [14624902.001]
  • [Cites] Acta Cytol. 2003 Jul-Aug;47(4):668-72 [12920764.001]
  • [Cites] Clin Nephrol. 2003 Mar;59(3):217-21 [12653267.001]
  • [Cites] Curr Urol Rep. 2009 Jan;10(1):11-6 [19116090.001]
  • [Cites] J Urol. 2008 Dec;180(6):2333-7 [18930274.001]
  • [Cites] J Endourol. 2008 Oct;22(10):2291-3 [18937593.001]
  • [Cites] J Urol. 2008 Aug;180(2):505-8; discussion 508-9 [18550113.001]
  • [Cites] Eur Urol. 2008 May;53(5):1003-11 [18061339.001]
  • [Cites] J Endourol. 2007 Aug;21(8):819-23 [17867935.001]
  • [Cites] J Endourol. 2007 Jul;21(7):709-13 [17705755.001]
  • [Cites] J Urol. 2007 Aug;178(2):379-86 [17561170.001]
  • [Cites] Acta Cytol. 2007 Jan-Feb;51(1):9-15 [17328488.001]
  • [Cites] AJR Am J Roentgenol. 2007 Feb;188(2):563-70 [17242269.001]
  • [Cites] J Urol. 2007 Feb;177(2):466-70; discussion 470 [17222611.001]
  • [Cites] Acta Cytol. 2006 Jul-Aug;50(4):466-8 [16901016.001]
  • [Cites] Urology. 2006 Jul;68(1 Suppl):7-13 [16857454.001]
  • [Cites] J Urol. 2005 May;173(5):1690-4 [15821559.001]
  • (PMID = 19955676.001).
  • [ISSN] 1998-3824
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2808655
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98. Kaya RA, Cavuşoğlu H, Tanik C, Kahyaoğlu O, Dilbaz S, Tuncer C, Aydin Y: Spinal cord compression caused by a brown tumor at the cervicothoracic junction. Spine J; 2007 Nov-Dec;7(6):728-32
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spinal cord compression caused by a brown tumor at the cervicothoracic junction.
  • BACKGROUND CONTEXT: Brown tumors are classic benign skeletal manifestations of hyperparathyroidism, but the spine involvement is very rare.
  • Of the reported 12 cases of spinal brown tumors in the literature, only in 5 were reconstructions with bone graft used.
  • PURPOSE: To describe our management in a patient with brown tumor and also to review the previous published cases.
  • METHODS: A case of a brown tumor in the T1 vertebra of a 72-year-old male patient is described.
  • He had a previous diagnosis of secondary hyperthyroidism caused by renal failure.
  • First, posterior transpedicular open biopsy was performed for the diagnosis and also for the decompression of the root causing brachialgia.
  • After the diagnosis of a brown tumor, the patient was reoperated through anterior approach for total tumor removal and reconstruction of the spine.
  • CONCLUSION: The determination of a spinal tumor in a patient with renal failure and hyperparathyroidism should bring to mind the probability of a brown tumor.
  • Although it is of a benign nature, it can cause severe neurologic deficit because of spinal compression.
  • The recommended treatment modality is surgical resection of the tumor, spinal reconstruction, and aggressive treatment of hyperparathyroidism both with parathyroidectomy and medically.
  • [MeSH-major] Hyperparathyroidism, Secondary / complications. Spinal Cord Compression / etiology. Spinal Neoplasms / complications
  • [MeSH-minor] Aged. Bone Transplantation. Decompression, Surgical. Humans. Magnetic Resonance Imaging. Male. Renal Insufficiency / complications. Spinal Fusion. Tomography, X-Ray Computed

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  • (PMID = 17998132.001).
  • [ISSN] 1529-9430
  • [Journal-full-title] The spine journal : official journal of the North American Spine Society
  • [ISO-abbreviation] Spine J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 18
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99. Jeon HG, Lee SR, Kim KH, Oh YT, Cho NH, Rha KH, Yang SC, Han WK: Benign lesions after partial nephrectomy for presumed renal cell carcinoma in masses 4 cm or less: prevalence and predictors in Korean patients. Urology; 2010 Sep;76(3):574-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign lesions after partial nephrectomy for presumed renal cell carcinoma in masses 4 cm or less: prevalence and predictors in Korean patients.
  • OBJECTIVES: To investigate the prevalence and predictors associated with benign lesions in Korean patients after partial nephrectomy for presumed renal cell carcinoma (RCC) for lesions measuring ≤ 4 cm.
  • METHODS: We retrospectively investigated the medical records of 376 patients who underwent partial nephrectomy for presumed RCC with renal masses of size ≤ 4 cm between June 1997 and December 2008.
  • Demographic and clinicopathologic parameters were compared between benign lesions and RCC.
  • Logistic regression was done to identify parameters associated with benign lesions.
  • RESULTS: In the 376 patients, 81 tumors (21.5%) were benign, including 35 angiomyolipomas (9.3%), 26 complicated cysts (6.9%), 11 oncocytomas (2.9%), and 9 others (2.4%).
  • Univariate analysis showed that time of surgery, female sex, younger age, and normal body mass index (body mass index (BMI) < 23 kg/m(2)) were associated with benign pathologic findings.
  • On multiple logistic regression analysis, female sex (OR, 4.91; 95% CI, 2.76-08.75; P < .001), age (OR, 0.97; 95% CI, 0.95-0.99; P = .009), and time of surgery (OR, 0.33; 95% CI, 0.11-0.95; P = .040) were independent predictors of benign histologic features.
  • Tumor size, incidental diagnosis, and BMI were not significant predictors (P > .05).
  • CONCLUSIONS: Our study with a large cohort of Asian patients showed that the prevalence of benign lesions was similar to previously reported Western studies.
  • However, the most common benign lesion was angiomyolipoma, compared with oncocytoma in Western countries.
  • The results of this study may help clinicians counsel female and younger patients recently diagnosed with small renal masses and decide the most appropriate treatment, including renal biopsies and close observation.
  • [MeSH-major] Carcinoma, Renal Cell / epidemiology. Carcinoma, Renal Cell / pathology. Kidney Neoplasms / epidemiology. Kidney Neoplasms / pathology. Nephrectomy
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Female. Humans. Male. Middle Aged. Predictive Value of Tests. Prevalence. Republic of Korea. Retrospective Studies. Young Adult


100. Klingler HC, Susani M: Focal therapy and imaging in prostate and kidney cancer: renal biopsy protocols before and after focal therapy. J Endourol; 2010 May;24(5):701-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Focal therapy and imaging in prostate and kidney cancer: renal biopsy protocols before and after focal therapy.
  • There is a continuous increase in incidentally diagnosed small renal masses, with a predominant rise in the elderly and frail population, making less invasive energy ablative therapy strategies more desirable.
  • In small renal masses, up to 30% benign tumors may be found, not necessitating any treatment.
  • Therefore, liberal use of renal mass biopsy (Bx) is mandatory before any focal therapy.






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