[X] Close
You are about to erase all the values you have customized, search history, page format, etc.
Click here to RESET all values       Click here to GO BACK without resetting any value
Items 1 to 70 of about 70
1. Wilkinson L, De P, Bloxham C: Mesothelial reaction in longstanding Crohn's ileitis simulating papillary mesothelioma. J Clin Pathol; 2008 Oct;61(10):1119-21
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesothelial reaction in longstanding Crohn's ileitis simulating papillary mesothelioma.
  • Changes in the connective tissue within the intestinal wall and surrounding tissue including mesenteric fat are characteristically seen in resected and autopsy specimens.
  • A rare and unusually florid mesothelial reaction in the surrounding small bowel serosa of a patient with a 2-year history of Crohn's ileitis is described.
  • The peritoneal surface of the ileal resection specimen displayed exuberant tubulo-papillary formations of the mesothelium, with superficial invasion of the underlying stroma.
  • The case demonstrates the well-recognised difficult differential diagnosis between a benign mesothelial proliferation and malignant mesothelioma in a novel clinical setting, and the diversity of the extramural manifestations of Crohn's disease.
  • [MeSH-major] Abdominal Neoplasms / pathology. Crohn Disease / pathology. Ileitis / pathology. Ileum / pathology. Mesothelioma / pathology
  • [MeSH-minor] Diagnosis, Differential. Epithelium / pathology. Female. Humans. Middle Aged. Peritoneum

  • MedlinePlus Health Information. consumer health - Crohn's Disease.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18820098.001).
  • [ISSN] 1472-4146
  • [Journal-full-title] Journal of clinical pathology
  • [ISO-abbreviation] J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  •  go-up   go-down


2. Dueñas García OF, Kerckoff Villanueva H, Rico Olvera H, Lira Plascencia J: [Benign peritoneal cystic mesothelioma as differential diagnose of an ovarian dependant tumor. Case report and review of the literature]. Ginecol Obstet Mex; 2007 Feb;75(2):111-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign peritoneal cystic mesothelioma as differential diagnose of an ovarian dependant tumor. Case report and review of the literature].
  • [Transliterated title] Mesotelioma quistico peritoneal benigno como diagnóstico diferencial de tumor dependiente del ovario. Comunicación de un caso y revisión bibliográfica.
  • Benign cystic mesothelioma is an uncommon lesion of the peritoneum, occurring predominantly in women of reproductive age.
  • The present case is a multitreated perimenopausal woman with lower urinary tract symptoms without clinical improvement despite the treatment, and pelvic pain with physical findings and radiology studies of a probable ovarian mass dependant tumoration, requiring protocolized exploratory laparotomy, finding a benign cystic mesothelioma.
  • [MeSH-major] Mesothelioma, Cystic / pathology. Ovarian Neoplasms / diagnosis. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Pelvic Pain / diagnosis. Pelvic Pain / etiology

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17542260.001).
  • [ISSN] 0300-9041
  • [Journal-full-title] Ginecología y obstetricia de México
  • [ISO-abbreviation] Ginecol Obstet Mex
  • [Language] spa
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Mexico
  •  go-up   go-down


3. Wheatley-Price P, Yang B, Patsios D, Patel D, Ma C, Xu W, Leighl N, Feld R, Cho BC, O'Sullivan B, Roberts H, Tsao MS, Tammemagi M, Anraku M, Chen Z, de Perrot M, Liu G: Soluble mesothelin-related Peptide and osteopontin as markers of response in malignant mesothelioma. J Clin Oncol; 2010 Jul 10;28(20):3316-22
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soluble mesothelin-related Peptide and osteopontin as markers of response in malignant mesothelioma.
  • PURPOSE: In malignant mesothelioma (MM), radiologic assessment of disease status is difficult.
  • Both soluble mesothelin-related peptide (SMRP) and osteopontin (OP) have utility in distinguishing MM from benign pleural disease.
  • [MeSH-major] Membrane Glycoproteins / blood. Mesothelioma / blood. Osteopontin / blood. Peritoneal Neoplasms / blood. Pleural Neoplasms / blood
  • [MeSH-minor] Biomarkers, Tumor / blood. Female. GPI-Linked Proteins. Humans. Male. Prognosis. Treatment Outcome

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • ClinicalTrials.gov. clinical trials - ClinicalTrials.gov .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20498407.001).
  • [ISSN] 1527-7755
  • [Journal-full-title] Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • [ISO-abbreviation] J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / mesothelin; 106441-73-0 / Osteopontin
  •  go-up   go-down


Advertisement
4. Zeren EH, Demirag F: Benign and Malignant Mesothelial Proliferation. Surg Pathol Clin; 2010 Mar;3(1):83-107
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign and Malignant Mesothelial Proliferation.
  • Malignant mesothelioma (MM) is a rare primary malignant tumor of the surface serosal cells.
  • The diagnosis of MM is challenging with a broad differential diagnosis.
  • For many decades, studies have focused on distinguishing MM from other types of cancer; however, benign mesothelial cell hyperplasia, especially in small biopsies, has emerged as a major problem.
  • The features of pleural lesions are somewhat different from peritoneal diseases, and this article primarily focuses on pleural diseases.
  • Thorough interpretation and correlation of clinical, radiologic, and pathologic findings are essential for a correct diagnosis.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright © 2010 Elsevier Inc. All rights reserved.
  • (PMID = 26839028.001).
  • [ISSN] 1875-9181
  • [Journal-full-title] Surgical pathology clinics
  • [ISO-abbreviation] Surg Pathol Clin
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Malignant mesothelioma / Mesothelial proliferations / Metastatic carcinoma / Pleural effusion
  •  go-up   go-down


5. Szöllósi A, Ferenc C, Pintér T, Erényi A, Nagy A: [Benign cystic mesothelioma, a rare tumor of the peritoneum]. Magy Seb; 2005 Feb;58(1):35-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign cystic mesothelioma, a rare tumor of the peritoneum].
  • [Transliterated title] Benignus cisztikus mesothelioma, a peritoneum ritka daganata.
  • Appendicetomy was performed, during the operation multiple cystic lesions were discovered on the right ovary and the peritoneal surface of the mesentery.
  • Final histology revealed benign cystic mesothelioma, which is a rare lesion of the peritoneum, occurring mainly in women in reproductive age.
  • The etiology of cystic mesothelioma is still unclear.
  • [MeSH-major] Mesothelioma, Cystic. Peritoneal Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16018599.001).
  • [ISSN] 0025-0295
  • [Journal-full-title] Magyar sebészet
  • [ISO-abbreviation] Magy Seb
  • [Language] hun
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Hungary
  •  go-up   go-down


6. Chua TC, Yan TD, Morris DL: Surgical biology for the clinician: peritoneal mesothelioma: current understanding and management. Can J Surg; 2009 Feb;52(1):59-64
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Surgical biology for the clinician: peritoneal mesothelioma: current understanding and management.
  • Mesothelioma is an asbestos-related tumour.
  • Mesothelioma in the thorax occurs on the pleura and is known as pleural mesothelioma.
  • It is the more common form of mesothelioma, accounting for 70% of cases.
  • It accounts for much of the remaining 30% and is known as peritoneal mesothelioma.
  • Early diagnosis of peritoneal mesothelioma is often difficult because the early symptoms are often overlooked as being a benign ailment of the gastrointestinal tract.
  • Therefore, diagnosis often occurs at an advanced stage when disease is widespread throughout the peritoneal cavity.
  • We update on the current understanding of peritoneal mesothelioma from a clinical perspective in hope that greater clinician awareness will promote best practice management of this condition.
  • [MeSH-major] Mesothelioma / diagnosis. Mesothelioma / therapy. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / therapy
  • [MeSH-minor] Asbestos / adverse effects. Biomarkers, Tumor. Chemotherapy, Cancer, Regional Perfusion. Diagnostic Imaging. Endoscopy, Gastrointestinal. Humans. Hyperthermia, Induced

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • Hazardous Substances Data Bank. ASBESTOS .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Ann Surg Oncol. 2007 Feb;14(2):515-25 [17031722.001]
  • [Cites] Ann Surg Oncol. 2007 Jan;14(1):41-9 [17039392.001]
  • [Cites] Ann Surg Oncol. 2007 Mar;14(3):1105-13 [17206478.001]
  • [Cites] Ann Oncol. 2007 May;18(5):827-34 [17130182.001]
  • [Cites] Ann Surg Oncol. 2007 Jun;14(6):1807-17 [17342564.001]
  • [Cites] Ann Surg Oncol. 2007 Aug;14(8):2270-80 [17464543.001]
  • [Cites] Carcinogenesis. 2007 Sep;28(9):2047-52 [17434931.001]
  • [Cites] MedGenMed. 2007;9(2):32 [17955087.001]
  • [Cites] Br J Surg. 2007 Nov;94(11):1408-14 [17631678.001]
  • [Cites] Ann Surg Oncol. 2008 Jan;15(1):125-33 [18030535.001]
  • [Cites] Ann Oncol. 2008 Feb;19(2):370-3 [18156144.001]
  • [Cites] Nat Clin Pract Oncol. 2008 Mar;5(3):136-47 [18227828.001]
  • [Cites] CMAJ. 2008 Mar 11;178(6):677-8 [18332380.001]
  • [Cites] J Cell Biochem. 1999 Dec;76(2):181-8 [10618635.001]
  • [Cites] Br J Surg. 2000 Nov;87(11):1587-93 [11091251.001]
  • [Cites] J Clin Gastroenterol. 2001 Sep;33(3):247-50 [11500619.001]
  • [Cites] Am Surg. 2001 Oct;67(10):999-1003 [11603562.001]
  • [Cites] Semin Oncol. 2002 Feb;29(1):2-17 [11836664.001]
  • [Cites] Cancer Res. 2002 Aug 1;62(15):4169-75 [12154012.001]
  • [Cites] J Clin Oncol. 2003 Jul 15;21(14):2636-44 [12860938.001]
  • [Cites] Tumori. 2003 May-Jun;89(3):269-73 [12908781.001]
  • [Cites] Clin Lung Cancer. 2003 Nov;5(3):177-81 [14667274.001]
  • [Cites] J Clin Oncol. 2003 Dec 15;21(24):4560-7 [14673042.001]
  • [Cites] Lung Cancer. 2004 Aug;45 Suppl 1:S21-3 [15261428.001]
  • [Cites] Ann Intern Med. 1982 Jun;96(6 Pt 1):746-55 [7091938.001]
  • [Cites] Br J Ind Med. 1983 May;40(2):145-52 [6299326.001]
  • [Cites] Lancet. 1985 Nov 2;2(8462):977-81 [2414612.001]
  • [Cites] Acta Cytol. 1987 May-Jun;31(3):369-73 [3035848.001]
  • [Cites] Environ Res. 1987 Oct;44(1):103-16 [3115771.001]
  • [Cites] Am J Pathol. 1987 Dec;129(3):448-62 [2827488.001]
  • [Cites] Exp Pathol. 1987;32(3):129-52 [3436395.001]
  • [Cites] J Cancer Res Clin Oncol. 1992;118(7):547-50 [1624547.001]
  • [Cites] Ann Surg. 1995 Jan;221(1):29-42 [7826158.001]
  • [Cites] Cancer Res. 1995 Feb 15;55(4):792-8 [7850791.001]
  • [Cites] Ann Surg. 1995 Feb;221(2):124-32 [7857141.001]
  • [Cites] Am J Physiol. 1995 Mar;268(3 Pt 1):L471-80 [7900829.001]
  • [Cites] Environ Health Perspect. 1994 Dec;102 Suppl 10:131-6 [7705288.001]
  • [Cites] Cancer Treat Res. 1996;82:359-74 [8849962.001]
  • [Cites] Cancer Res. 1996 Dec 1;56(23):5334-8 [8968079.001]
  • [Cites] Histopathology. 1997 May;30(5):403-18 [9181361.001]
  • [Cites] Eur J Surg Oncol. 2005 Feb;31(1):53-8 [15642426.001]
  • [Cites] Tumori. 2005 Jan-Feb;91(1):1-5 [15849996.001]
  • [Cites] Lung Cancer. 2005 Jul;49 Suppl 1:S3-8 [15950797.001]
  • [Cites] Am J Clin Pathol. 2005 May;123(5):724-37 [15981812.001]
  • [Cites] Int J Occup Environ Health. 2005 Jul-Sep;11(3):254-8 [16130966.001]
  • [Cites] N Engl J Med. 2005 Oct 13;353(15):1564-73 [16221779.001]
  • [Cites] N Engl J Med. 2005 Oct 13;353(15):1591-603 [16221782.001]
  • [Cites] Clin Cancer Res. 2006 Jan 15;12(2):447-53 [16428485.001]
  • [Cites] Ann Surg Oncol. 2006 Mar;13(3):405-12 [16485159.001]
  • [Cites] J Exp Clin Cancer Res. 2003 Dec;22(4 Suppl):41-5 [16767905.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Jul 5;103(27):10397-402 [16798876.001]
  • [Cites] Ann Oncol. 2006 Nov;17(11):1615-9 [16600983.001]
  • [Cites] Ann N Y Acad Sci. 2006 Sep;1076:871-81 [17119263.001]
  • [Cites] Ann Surg Oncol. 2007 Feb;14(2):500-8 [17151789.001]
  • (PMID = 19234654.001).
  • [ISSN] 1488-2310
  • [Journal-full-title] Canadian journal of surgery. Journal canadien de chirurgie
  • [ISO-abbreviation] Can J Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Canada
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 1332-21-4 / Asbestos
  • [Number-of-references] 54
  • [Other-IDs] NLM/ PMC2637623
  •  go-up   go-down


7. Yamamuro M, Gerbaudo VH, Gill RR, Jacobson FL, Sugarbaker DJ, Hatabu H: Morphologic and functional imaging of malignant pleural mesothelioma. Eur J Radiol; 2007 Dec;64(3):356-66
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphologic and functional imaging of malignant pleural mesothelioma.
  • Malignant pleural mesothelioma (MPM) is an aggressive tumor that arises from the pleura and frequently extends to adjacent structures.
  • Major findings include nodular pleural thickening, unilateral pleural effusion, and tumor invasion of adjacent structures.
  • CT tends to underestimate early chest wall invasion and peritoneal involvement and has well-known limitations in the evaluation of lymph node metastases.
  • Because of its excellent contrast resolution, MRI is superior to CT, both in the differentiation of malignant from benign pleural disease, and in the assessment of chest wall and diaphragmatic involvement.
  • Perfusion MRI is the most promising technique for the assessment of the tumor microvasculature.
  • It has been shown that FDG-PET is useful for the differentiation of benign from malignant lesions, for staging and monitoring metabolic response to therapy against MPM, and that it has prognostic value.
  • An initial report on PET/CT imaging of MPM has shown increased accuracy of overall staging, improving the assessment of tumor resectability.
  • [MeSH-major] Diagnostic Imaging / methods. Mesothelioma / diagnosis. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Humans. Magnetic Resonance Imaging / methods. Neoplasm Staging. Neovascularization, Pathologic / diagnosis. Positron-Emission Tomography / methods. Tomography, X-Ray Computed / methods


8. van Bijsterveldt C, Willemsen W, Bulten J: Peritoneal benign mesothelioma during and after two pregnancies. Eur J Obstet Gynecol Reprod Biol; 2006 Aug;127(2):265-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peritoneal benign mesothelioma during and after two pregnancies.
  • [MeSH-major] Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Pregnancy Complications, Neoplastic / diagnosis. Pseudomyxoma Peritonei / diagnosis

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - Tumors and Pregnancy.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16527388.001).
  • [ISSN] 0301-2115
  • [Journal-full-title] European journal of obstetrics, gynecology, and reproductive biology
  • [ISO-abbreviation] Eur. J. Obstet. Gynecol. Reprod. Biol.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Ireland
  •  go-up   go-down


9. Gupta A, Dionello R, Winslet MC, Tadrous P: Benign papillary mesothelioma of the peritoneum in association with gastric adenocarcinoma. N Z Med J; 2007;120(1248):U2394
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign papillary mesothelioma of the peritoneum in association with gastric adenocarcinoma.
  • [MeSH-major] Adenocarcinoma / surgery. Mesothelioma / pathology. Peritoneal Neoplasms / pathology. Stomach Neoplasms / surgery

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - Stomach Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17277811.001).
  • [ISSN] 1175-8716
  • [Journal-full-title] The New Zealand medical journal
  • [ISO-abbreviation] N. Z. Med. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] New Zealand
  •  go-up   go-down


10. Ohar JA, Ampleford EJ, Howard SE, Sterling DA: Identification of a mesothelioma phenotype. Respir Med; 2007 Mar;101(3):503-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification of a mesothelioma phenotype.
  • Despite the strong association of asbestos exposure to mesothelioma, only a fraction of persons exposed develop this neoplasm which is characterized by long latency and shortened survival.
  • Familial clustering implicates both exposure and genetic predisposition as causative, but a biologically relevant mesothelioma phenotype essential to genetic analysis has not been defined.
  • To identify a more extensive set of traits that would define a mesothelioma phenotype for the purpose of genetic analysis, we set to determine characteristics that distinguish mesothelioma patients from others exposed to asbestos and to identify factors that predict the presence of mesothelioma over other mesenchymal tumors of the peritoneum and carcinoma metastatic to the pleura.
  • We compared demographics in four asbestos-exposed groups (controls n=347, bronchogenic cancer n=67, mesothelioma n=179 and benign asbestos-induced lung disease (BALD) n=3757).
  • Within the mesothelioma group, we compared traits to identify characteristics associated with shortened survival.
  • We found that compared to other asbestos-exposed groups, subjects with mesothelioma were younger at first asbestos exposure, had a greater risk of a second cancer diagnosis (odds ratio=3.29), had a longer disease latency, and had a greater risk of cancer among first-degree relatives (point estimate for risk 2.93; 95% CI 2.5-3.5).
  • Thoracic tumor location, work exposure and male gender were consistently associated with shortened survival (1.9+/-1.3 years).
  • We conclude that thoracic tumor location, work exposure, male gender, long latency, early age at first exposure, presence of a second cancer, and first-degree relative with cancer define a phenotype that sets mesothelioma patients with a short survival apart from other asbestos-exposed individuals.
  • [MeSH-major] Asbestos / adverse effects. Lung Neoplasms / genetics. Mesothelioma / genetics. Occupational Diseases / genetics
  • [MeSH-minor] Age Factors. Aged. Educational Status. Family Health. Female. Humans. Male. Middle Aged. Neoplasms, Multiple Primary. Occupational Exposure / adverse effects. Peritoneal Neoplasms / genetics. Peritoneal Neoplasms / mortality. Phenotype. Pleural Neoplasms / genetics. Pleural Neoplasms / mortality. Risk Factors. Sex Factors. Smoking / adverse effects


11. Lyons-Boudreaux V, Mody DR, Zhai J, Coffey D: Cytologic malignancy versus benignancy: how useful are the "newer" markers in body fluid cytology? Arch Pathol Lab Med; 2008 Jan;132(1):23-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: Differentiating reactive effusion, malignant mesothelioma, and metastatic adenocarcinoma in body cavity fluids can be challenging.
  • OBJECTIVE: To evaluate the efficacy of 5 immunohistochemical markers in the differential diagnosis of reactive mesothelial proliferation, malignant mesothelioma, and metastatic adenocarcinoma in body cavity fluids.
  • DESIGN: A total of 72 formalin-fixed, paraffin-embedded cell block specimens from pleural and peritoneal effusions, including 5 mesotheliomas, 48 adenocarcinomas, and 19 benign effusions were stained with antibodies against calretinin, D2-40, XIAP, MOC-31, and WT1.
  • RESULTS: All benign effusions and mesotheliomas demonstrated diffuse membranous staining with D2-40.
  • All mesotheliomas displayed calretinin positivity, whereas only 58% of benign effusions stained focally with calretinin.
  • MOC-31 was positive in all cases of adenocarcinoma, whereas all benign effusions and mesotheliomas were negative.
  • However, background reactive mesothelial cells were positive for calretinin and D2-40.
  • Overall, D2-40 highlighted more mesothelial cells than calretinin.
  • WT1 was positive in 50% of benign effusions, 60% of mesotheliomas, and 27% of adenocarcinomas.
  • XIAP stained most mesotheliomas (80%), some adenocarcinomas (51%), and rare benign effusions (11%).
  • CONCLUSIONS: MOC-31 and D2-40 were very sensitive and specific markers of epithelial and mesothelial cells, respectively.
  • Compared with calretinin, D2-40 was a more sensitive marker of mesothelial cells.
  • [MeSH-major] Adenocarcinoma. Biomarkers, Tumor / analysis. Body Fluids / chemistry. Epithelium / chemistry. Mesothelioma / chemistry. Pleural Effusion, Malignant / chemistry
  • [MeSH-minor] Antibodies, Monoclonal / analysis. Antibodies, Monoclonal, Murine-Derived. Calbindin 2. Cell Proliferation. Diagnosis, Differential. Humans. Hyperplasia / diagnosis. S100 Calcium Binding Protein G / analysis. WT1 Proteins / analysis. X-Linked Inhibitor of Apoptosis Protein / analysis

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18181669.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antibodies, Monoclonal; 0 / Antibodies, Monoclonal, Murine-Derived; 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calbindin 2; 0 / S100 Calcium Binding Protein G; 0 / WT1 Proteins; 0 / X-Linked Inhibitor of Apoptosis Protein; 0 / XIAP protein, human; 0 / monoclonal antibody D2-40
  •  go-up   go-down


12. McCluggage WG, Wilkinson N: Metastatic neoplasms involving the ovary: a review with an emphasis on morphological and immunohistochemical features. Histopathology; 2005 Sep;47(3):231-47
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Peritoneal tumours, including primary peritoneal carcinoma, mesothelioma and intra-abdominal desmoplastic small round cell tumour, involving the ovary are also discussed, together with a variety of other rare, metastatic ovarian neoplasms.
  • Many metastatic adenocarcinomas involving the ovary, especially those exhibiting mucinous differentiation, closely mimic primary ovarian adenocarcinomas with morphologically bland areas simulating benign and borderline cystadenoma.
  • While immunohistochemistry undoubtedly has a valuable role to play and is paramount in diagnosis in some cases, the results must be interepreted with caution, especially in mucinous tumours, and within the relevant clinical context.

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16115224.001).
  • [ISSN] 0309-0167
  • [Journal-full-title] Histopathology
  • [ISO-abbreviation] Histopathology
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Intermediate Filament Proteins; 0 / KRT20 protein, human; 0 / KRT7 protein, human; 0 / Keratin-20; 0 / Keratin-7; 68238-35-7 / Keratins
  • [Number-of-references] 114
  •  go-up   go-down


13. Vallerie AM, Lerner JP, Wright JD, Baxi LV: Peritoneal inclusion cysts: a review. Obstet Gynecol Surv; 2009 May;64(5):321-34
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Peritoneal inclusion cysts: a review.
  • OBJECTIVE: To provide a comprehensive review of peritoneal inclusion cysts in the female patient population.
  • DATA SOURCES: We searched the MEDLINE database for articles with keywords "peritoneal inclusion cyst" and "benign (multicystic) mesothelioma."
  • All reports included a tissue-confirmed diagnosis, except 1.
  • METHOD OF STUDY: We evaluated all studies meeting our criteria for clinical features, histologic criteria for diagnosis, imaging and laboratory studies, and treatment modalities.
  • CONCLUSION: This is a comprehensive review of peritoneal inclusion cysts.
  • We specifically focus on the method of diagnosis and management.
  • Peritoneal inclusion cysts have minimal mortality but high morbidity.
  • Diagnosis is made by clinical history, ultrasound imaging, and CA-125 correlation.
  • Tissue sample is necessary for definitive diagnosis.
  • LEARNING OBJECTIVES: After completion of this article, the reader should be able to summarize imaging characteristics of peritoneal inclusion cysts, explain the epidemiology and risk factors for the development of peritoneal inclusion cysts, and describe possible treatment options for peritoneal inclusion cysts.
  • [MeSH-major] Mesothelioma, Cystic. Peritoneal Neoplasms

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Obstet Gynecol Surv. 2009 Nov;64(11):769
  • (PMID = 19386139.001).
  • [ISSN] 1533-9866
  • [Journal-full-title] Obstetrical & gynecological survey
  • [ISO-abbreviation] Obstet Gynecol Surv
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contraceptives, Oral, Hormonal; 33515-09-2 / Gonadotropin-Releasing Hormone
  • [Number-of-references] 59
  •  go-up   go-down


14. Koo PJ, Wills JS: Case 146: Benign multicystic mesothelioma. Radiology; 2009 Jun;251(3):944-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Case 146: Benign multicystic mesothelioma.
  • [MeSH-major] Mesothelioma, Cystic / radiography. Mesothelioma, Cystic / ultrasonography. Peritoneal Neoplasms / radiography. Peritoneal Neoplasms / ultrasonography
  • [MeSH-minor] Adult. Contrast Media. Diagnosis, Differential. Female. Humans. Iohexol. Tomography, X-Ray Computed. Ultrasonography, Doppler

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19474381.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media; 4419T9MX03 / Iohexol
  •  go-up   go-down


15. Tarrés J, Abós-Herràndiz R, Albertí C, Martínez-Artés X, Rosell-Murphy M, García-Allas I, Krier I, Castro E, Cantarell G, Gallego M, Orriols R: [Asbestos-related diseases in a population near a fibrous cement factory]. Arch Bronconeumol; 2009 Sep;45(9):429-34
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • MATERIAL AND METHODS: We retrospectively collected information available on patients with asbestos-related diseases who at the time of diagnosis had resided in the area near the fibrous cement factory.
  • Of the 1107 asbestos-related disease cases identified, 86.5% were benign and 8.4% pleural mesothelioma.
  • [MeSH-major] Asbestos / adverse effects. Asbestosis / epidemiology. Construction Materials. Environmental Exposure. Lung Neoplasms / epidemiology. Mesothelioma / epidemiology. Peritoneal Neoplasms / epidemiology. Pleural Neoplasms / epidemiology

  • MedlinePlus Health Information. consumer health - Asbestos.
  • MedlinePlus Health Information. consumer health - Lung Cancer.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • Hazardous Substances Data Bank. ASBESTOS .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19501947.001).
  • [ISSN] 1579-2129
  • [Journal-full-title] Archivos de bronconeumología
  • [ISO-abbreviation] Arch. Bronconeumol.
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Spain
  • [Chemical-registry-number] 1332-21-4 / Asbestos
  •  go-up   go-down


16. Safioleas MC, Constantinos K, Michael S, Konstantinos G, Constantinos S, Alkiviadis K: Benign multicystic peritoneal mesothelioma: a case report and review of the literature. World J Gastroenterol; 2006 Sep 21;12(35):5739-42
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma: a case report and review of the literature.
  • Benign multicystic peritoneal mesothelioma (BMPM) is a rare tumor that occurs mainly in women in their reproductive age.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Middle Aged. Neoplasm Recurrence, Local. Neoplasms / diagnosis. Neoplasms / etiology. Neoplasms / pathology. Neoplasms / surgery


17. Reid A, de Klerk N, Ambrosini G, Olsen N, Pang SC, Musk AW: The additional risk of malignant mesothelioma in former workers and residents of Wittenoom with benign pleural disease or asbestosis. Occup Environ Med; 2005 Oct;62(10):665-9
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The additional risk of malignant mesothelioma in former workers and residents of Wittenoom with benign pleural disease or asbestosis.
  • AIMS: To examine the hypothesis that people with benign pleural disease or asbestosis have an increased risk of malignant mesothelioma beyond that attributable to their degree of asbestos exposure.
  • The first plain chest radiograph taken at the time of recruitment into the cancer prevention programme was read for evidence of benign pleural disease and asbestosis, using the UICC classification.
  • Cox proportional hazards modelling was used to relate benign pleural disease, asbestosis, asbestos exposure, and mesothelioma.
  • RESULTS: Between 1990 and 2002, there were 76 cases of mesothelioma (56 of the pleura and 20 of the peritoneum).
  • Cases had more radiographic evidence of (all) benign pleural disease, pleural thickening, blunt/obliterated costophrenic angle, and asbestosis than non-cases.
  • Adjusting for time since first exposure (log years), cumulative exposure (log f/ml-years), and age at the start of the programme, pleural thickening (OR = 3.1, 95% CI 1.2 to 7.6) and asbestosis (OR = 3.3, 95% CI 1.3 to 8.6) were associated with an increased risk of peritoneal mesothelioma.
  • There was no increased risk for pleural mesothelioma.
  • CONCLUSION: The presence of benign pleural disease, in particular pleural thickening, and asbestosis appears to increase the risk of mesothelioma of the peritoneum, but not of the pleura beyond that attributable to indices of asbestos exposure in this cohort of subjects exposed to crocidolite.
  • [MeSH-major] Asbestosis / complications. Lung Neoplasms / etiology. Mesothelioma / etiology. Occupational Exposure. Pleural Diseases / complications


18. Davidson B, Skrede M, Silins I, Shih IeM, Trope CG, Flørenes VA: Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma. Cancer; 2007 Sep 15;110(6):1264-71
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Low-molecular weight forms of cyclin E differentiate ovarian carcinoma from cells of mesothelial origin and are associated with poor survival in ovarian carcinoma.
  • BACKGROUND: The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays.
  • In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant mesothelioma, and benign reactive effusions.
  • RESULTS: LMW forms of cyclin E were identified in 54 of 72 ovarian carcinoma effusions (75%) compared with 1 of 14 malignant mesothelioma effusions (7%) and 1 of 12 reactive effusions (8%) (P < .001).
  • CONCLUSIONS: LMW forms of cyclin E differentiated ovarian carcinoma from benign and malignant mesothelial cells and were associated with increased protein expression using immunohistochemistry.
  • [MeSH-major] Biomarkers, Tumor / analysis. Carcinoma / chemistry. Carcinoma / mortality. Cyclin E / analysis. Mesothelioma / chemistry. Mesothelioma / mortality. Ovarian Neoplasms / chemistry. Ovarian Neoplasms / mortality


19. Christensen H, Waldstrøm M: [Multicystic peritoneal mesothelioma is an uncommon lesion that is most often discovered incidentally]. Ugeskr Laeger; 2008 Mar 10;170(11):958
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Multicystic peritoneal mesothelioma is an uncommon lesion that is most often discovered incidentally].
  • The lesion is benign with a favourable prognosis but local recurrence is reported not to be rare, and in a few cases malignant transformation has been described.
  • [MeSH-major] Mesothelioma / pathology. Peritoneal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18397627.001).
  • [ISSN] 1603-6824
  • [Journal-full-title] Ugeskrift for laeger
  • [ISO-abbreviation] Ugeskr. Laeg.
  • [Language] dan
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Denmark
  •  go-up   go-down


20. Chiosea S, Krasinskas A, Cagle PT, Mitchell KA, Zander DS, Dacic S: Diagnostic importance of 9p21 homozygous deletion in malignant mesotheliomas. Mod Pathol; 2008 Jun;21(6):742-7
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Definitive diagnosis of malignant mesothelioma in small specimens can be extremely difficult based on morphology alone.
  • Recent studies demonstrated that this alteration may be useful for differentiating benign from malignant mesothelial proliferations in cytology specimens.
  • The aim of this study was to evaluate the diagnostic utility of homozygous deletion of 9p21 assessed by fluorescence in situ hybridization (FISH) in mesothelial proliferations involving serosal surfaces in paraffin-embedded tissue. p16 protein immunoexpression was also explored as a potential diagnostic aid.
  • FISH analysis demonstrated homozygous deletion of the 9p21 locus in 35 of 52 cases (67%) of pleural mesothelioma and in 5 of 20 cases of peritoneal mesothelioma (25%) (P<0.005).
  • None of 40 cases of reactive pleural mesothelial proliferations showed p16 deletion (P<0.005).
  • Loss of immunoexpression of p16 was observed in 71% of the peritoneal mesotheliomas, 40% of the pleural malignant mesotheliomas and 15% of the reactive mesothelial cells.
  • Our study suggests that 9p21 homozygous deletion assessed by FISH on paraffin-embedded tissue may be helpful for differentiating between malignant mesotheliomas and reactive mesothelial proliferations.
  • A discrepancy between p16 protein expression and homozygous deletion suggests that other molecular mechanisms may play a role in p16 protein expression in mesothelial proliferations.
  • [MeSH-major] Gene Deletion. Genes, p16. Mesothelioma / genetics. Peritoneal Neoplasms / genetics. Pleural Neoplasms / genetics
  • [MeSH-minor] Biomarkers, Tumor / analysis. Humans. Immunohistochemistry. In Situ Hybridization, Fluorescence

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18327208.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


21. Takeda M, Kasai T, Enomoto Y, Takano M, Morita K, Kadota E, Nonomura A: 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis. Pathol Int; 2010 May;60(5):395-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] 9p21 deletion in the diagnosis of malignant mesothelioma, using fluorescence in situ hybridization analysis.
  • Previous studies showed that this alteration might be useful for differentiating benign from malignant mesothelial tumors in cytology and surgical specimens.
  • The purpose of this study is to evaluate the diagnostic utility of 9p21 homozygous deletion assessed by FISH in mesothelial neoplasm and hyperplasia of Japanese patients using paraffin-embedded tissue.
  • In contrast, no cases of adenomatoid tumor, benign mesothelial multicystic tumor, reactive mesothelial hyperplasia or pleuritis showed 9p21 deletion (P < 0.005).
  • 9p21 homozygous deletion correlated well with p16 protein expression in the tumor cells.
  • Our study suggests that 9p21 homozygous deletion assessed by FISH on paraffin-embedded tissue may be very useful for differentiating MM from reactive mesothelial proliferation.
  • [MeSH-major] Chromosomes, Human, Pair 9. Genes, p16. Heart Neoplasms / diagnosis. In Situ Hybridization, Fluorescence / methods. Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Biomarkers, Tumor / genetics. Biomarkers, Tumor / metabolism. DNA, Neoplasm / analysis. Epithelium / pathology. Female. Gene Deletion. Gene Dosage. Humans. Pericardium / metabolism. Pericardium / pathology

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 20518890.001).
  • [ISSN] 1440-1827
  • [Journal-full-title] Pathology international
  • [ISO-abbreviation] Pathol. Int.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / DNA, Neoplasm
  •  go-up   go-down


22. Cabay RJ, Siddiqui NH, Alam S: Paratesticular papillary mesothelioma: a case with borderline features. Arch Pathol Lab Med; 2006 Jan;130(1):90-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Paratesticular papillary mesothelioma: a case with borderline features.
  • Most often, mesotheliomas involve the serosal (serous) membranes of the pleura and peritoneum.
  • Sometimes, mesothelial proliferations are identified in other locations.
  • On very rare occasions, a mesothelioma is found within the tunica vaginalis of the paratesticular region.
  • We report a case of papillary mesothelioma of the tunica vaginalis in a 52-year-old man.
  • Although this lesion had papillary structures lined by a single layer of mesothelial cells with predominantly bland nuclear and cytologic features, there was evidence of a minimal presence of mesothelial cells in the underlying stroma.
  • This combination of benign and semimalignant characteristics can make the diagnosis of such a lesion problematic.
  • We think that a diagnosis of "borderline papillary mesothelioma" can be considered for similar mesothelial proliferations to allow for a possible increase in diagnostic accuracy and provide an enhanced informational platform from which patients and clinicians can benefit.
  • [MeSH-major] Mesothelioma / pathology. Peritoneal Neoplasms / pathology. Testicular Neoplasms / pathology. Testis / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Disease-Free Survival. Humans. Immunohistochemistry. Male. Middle Aged. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - Testicular Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16390245.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


23. Ikeda K, Tate G, Suzuki T, Kitamura T, Mitsuya T: IMP3/L523S, a novel immunocytochemical marker that distinguishes benign and malignant cells: the expression profiles of IMP3/L523S in effusion cytology. Hum Pathol; 2010 May;41(5):745-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] IMP3/L523S, a novel immunocytochemical marker that distinguishes benign and malignant cells: the expression profiles of IMP3/L523S in effusion cytology.
  • Differentiating reactive mesothelial cells from metastatic carcinoma and malignant mesothelioma is critical in effusion cytology.
  • Numerous immunohistochemical/cytochemical reports use various antibodies in effusion samples, and most antibodies differentiate metastatic adenocarcinoma from malignant mesothelioma, but no antibodies help distinguish malignant mesothelioma from reactive mesothelial cells.
  • A total of 229 cases of pleural and peritoneal effusion cytospecimens were evaluated for the study, including 39 benign effusions with reactive mesothelial cells and 190 metastatic malignant effusions.
  • IMP3 immunoreactivity was observed in 2 (5.1%) of 39 cases of reactive mesothelial cells, 138 (72.6%) of 190 cases of malignant effusion, 4 (36.4%) of 11 cases of malignant mesothelioma, 106 (75.7%) of 140 cases of metastatic adenocarcinoma, and 8 (100%) of 8 cases of squamous cell carcinoma.
  • The overall specificity for the diagnosis of malignancy was 94.9%, whereas the sensitivity was 72.6%.
  • In the peritoneal effusions, the sensitivity for the diagnosis of metastatic adenocarcinoma to distinguish reactive mesothelial cells was 92.3%.
  • However, the IMP3 antibody is a highly specific marker for malignant lesions, and thus, IMP3 staining is useful for distinguishing neoplastic cells from reactive mesothelial cells in effusion samples.
  • [MeSH-major] Adenocarcinoma / metabolism. Ascitic Fluid / metabolism. Biomarkers, Tumor / metabolism. Mesothelioma / metabolism. Neoplasm Proteins / metabolism. Pleural Effusion, Malignant / metabolism. RNA-Binding Proteins / metabolism

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20060157.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / IMP3 protein, human; 0 / Neoplasm Proteins; 0 / RNA-Binding Proteins
  •  go-up   go-down


24. Factor RE, Dal Cin P, Fletcher JA, Cibas ES: Cytogenetics and fluorescence in situ hybridization as adjuncts to cytology in the diagnosis of malignant mesothelioma. Cancer; 2009 Aug 25;117(4):247-53
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytogenetics and fluorescence in situ hybridization as adjuncts to cytology in the diagnosis of malignant mesothelioma.
  • Although the chromosome regions affected by these aberration(s) may vary from 1 tumor to another, certain regions are commonly disrupted.
  • These aberrations are absent in benign mesothelial cells, and therefore their presence can be used to confirm a diagnosis of MM.
  • METHODS: A retrospective analysis of 48 pleural or peritoneal fluids from patients with histologically confirmed MM was performed.
  • [MeSH-major] Chromosome Aberrations. In Situ Hybridization, Fluorescence / methods. Mesothelioma / genetics


25. Pickhardt PJ, Bhalla S: Primary neoplasms of peritoneal and sub-peritoneal origin: CT findings. Radiographics; 2005 Jul-Aug;25(4):983-95
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Primary neoplasms of peritoneal and sub-peritoneal origin: CT findings.
  • Peritoneal carcinomatosis is a common metastatic manifestation of many organ-based malignancies, particularly carcinomas of the gastrointestinal tract and ovaries.
  • Primary neoplasms of peritoneal and sub-peritoneal origin occur much less frequently than metastatic peritoneal involvement from a known or occult primary tumor; however, these rare primary lesions (peritoneal mesothelioma, papillary serous carcinoma, desmoplastic small round cell tumor, benign and malignant mesenchymal tumors, lymphoproliferative disorders) are often first detected at computed tomography (CT) and should be considered in the absence of a known or suspected organ-based malignancy.
  • A precise diagnosis based on imaging findings alone is often not possible.
  • Furthermore, distinguishing a benign from a malignant process and a primary from a metastatic process is also challenging.
  • Nevertheless, CT features combined with the patient's relevant clinical and demographic data can help narrow the differential diagnosis for a peritoneum-based neoplasm in many cases.
  • CT is useful not only for the detection, characterization, and staging of primary neoplasms of peritoneal and subperitoneal origin, but also for guiding biopsy for tissue diagnosis.
  • [MeSH-major] Peritoneal Neoplasms / radiography. Tomography, X-Ray Computed

  • MedlinePlus Health Information. consumer health - CT Scans.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16009819.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 20
  •  go-up   go-down


26. Gill RR, Gerbaudo VH, Sugarbaker DJ, Hatabu H: Current trends in radiologic management of malignant pleural mesothelioma. Semin Thorac Cardiovasc Surg; 2009;21(2):111-20
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Current trends in radiologic management of malignant pleural mesothelioma.
  • Malignant pleural mesothelioma (MPM) is an aggressive pleural tumor with a complex growth pattern.
  • Imaging plays a crucial role in diagnosis and management.
  • Computed tomography (CT) has been the mainstay in the clinical evaluation of MPM; however it underestimates early chest wall invasion, peritoneal involvement, and has well-known limitations in nodal metastatic evaluation.
  • Magnetic resonance imaging (MRI) is superior to CT, both in the differentiation of malignant from benign pleural disease and in the assessment of chest wall and diaphragmatic involvement.
  • Perfusion and diffusion MRI are promising new techniques for the assessment of tumor cellularity and microvasculature and can be used for quantitative and qualitative assessment of treatment response.
  • Fluorodeoxyglucose positron emission tomography (FDG-PET) is useful for the differentiation of benign from malignant lesions, for staging, and for monitoring response to therapy.
  • [MeSH-major] Magnetic Resonance Imaging / trends. Mesothelioma / diagnosis. Pleural Neoplasms / diagnosis. Positron-Emission Tomography / trends. Tomography, X-Ray Computed / trends
  • [MeSH-minor] Antineoplastic Agents / therapeutic use. Fluorodeoxyglucose F18. Humans. Lymphatic Metastasis. Neoplasm Invasiveness. Neoplasm Staging. Palliative Care. Pleural Effusion, Malignant / diagnosis. Predictive Value of Tests. Radiopharmaceuticals. Thoracic Surgical Procedures. Treatment Outcome

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - CT Scans.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - MRI Scans.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19822282.001).
  • [ISSN] 1043-0679
  • [Journal-full-title] Seminars in thoracic and cardiovascular surgery
  • [ISO-abbreviation] Semin. Thorac. Cardiovasc. Surg.
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R21 CA116271
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Radiopharmaceuticals; 0Z5B2CJX4D / Fluorodeoxyglucose F18
  • [Number-of-references] 30
  •  go-up   go-down


27. Chammakhi-Jemli C, Ben Hassine L, Dahmani Z, Khlifi S, Labbène N, Mzabi H, Shili-Briki S, Daghfous MH: [Benign cystic mesothelioma of the peritoneum]. Tunis Med; 2008 Jun;86(6):626-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Benign cystic mesothelioma of the peritoneum].
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Peritoneal Neoplasms / diagnosis

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19222141.001).
  • [ISSN] 0041-4131
  • [Journal-full-title] La Tunisie médicale
  • [ISO-abbreviation] Tunis Med
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Tunisia
  •  go-up   go-down


28. Samson P, Cacala S: Rare case of benign multicystic peritoneal mesothelioma. ANZ J Surg; 2005 Jul;75(7):619-20
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rare case of benign multicystic peritoneal mesothelioma.
  • [MeSH-major] Hernia, Inguinal / surgery. Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] ANZ J Surg. 2006 May;76(5):421-2 [16768710.001]
  • [CommentOn] ANZ J Surg. 2001 Oct;71(10):615-8 [11552941.001]
  • (PMID = 15972062.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Australia
  •  go-up   go-down


29. Lanneau GS, McLaughlin D, O'Boyle J, Magann EF, Morrison JC: Well-differentiated papillary mesothelioma of the uterine serosa identified at cesarean section: a case report. J Reprod Med; 2005 Nov;50(11):860-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Well-differentiated papillary mesothelioma of the uterine serosa identified at cesarean section: a case report.
  • BACKGROUND: Peritoneal mesotheliomas encompass a variety of benign and malignant neoplasms.
  • Well-differentiated papillary mesothelioma (WDPM) is uncommon, is thought to be of low malignant potential and is often discovered incidentally during abdominal or pelvic surgery.
  • A 2-cm, polypoid lesion was excised from the posterior uterine fundus; final pathology showed well-differentiated papillary mesothelioma.
  • A follow-up laparoscopic examination with abdominal washing for cytology and peritoneal biopsies revealed no residual disease.
  • Knowledge of the variable disease spectrum of mesothelioma is important in patient counseling and management.
  • Differentiating between WDPM and malignant mesothelioma, other peritoneal tumors and implants from primary sites is necessary to avoid overtreatment.
  • [MeSH-major] Cesarean Section. Mesothelioma / diagnosis. Uterine Neoplasms / diagnosis
  • [MeSH-minor] Adult. Cytodiagnosis. Diagnosis, Differential. Female. Humans. Pregnancy. Treatment Outcome

  • MedlinePlus Health Information. consumer health - Cesarean Section.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - Uterine Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16419636.001).
  • [ISSN] 0024-7758
  • [Journal-full-title] The Journal of reproductive medicine
  • [ISO-abbreviation] J Reprod Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


30. Jerbi M, Hidar S, Ziadi S, Khairi H: Benign multicystic peritoneal mesothelioma. Int J Gynaecol Obstet; 2006 Jun;93(3):267-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma.
  • [MeSH-major] Mesothelioma / pathology. Mesothelioma, Cystic / pathology. Neoplasms, Connective Tissue / pathology. Peritoneal Neoplasms / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adult. Female. Humans. Immunohistochemistry. Laparotomy. Peritoneum / diagnostic imaging. Peritoneum / pathology. Peritoneum / surgery. Pregnancy. Radiography. Ultrasonography

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16687143.001).
  • [ISSN] 0020-7292
  • [Journal-full-title] International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
  • [ISO-abbreviation] Int J Gynaecol Obstet
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


31. Kemp AM, Nayar R, De Frias D, Lin X: Cytomorphologic characteristics of fine needle core biopsy of multicystic peritoneal mesothelioma: a case report and review of the literature. Diagn Cytopathol; 2010 Mar;38(3):192-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytomorphologic characteristics of fine needle core biopsy of multicystic peritoneal mesothelioma: a case report and review of the literature.
  • Multicystic peritoneal mesothelioma (MPM) is an uncommon cystic mesothelial proliferative lesion.
  • The preoperative diagnosis of MPM is difficult to establish based on clinical and radiographic findings, and has therefore traditionally been diagnosed following surgical resection.
  • Due to differing management of MPM and its differential diagnoses including both benign and malignant lesions, it would be beneficial to diagnose MPM preoperatively.
  • The cytomorphologic features of needle core biopsy, immunocytochemical studies and differential diagnosis are discussed.
  • Furthermore, despite its infrequency, the current case emphasizes the importance of the inclusion of this entity in the differential diagnosis of cystic lesions of the abdomen and pelvis at the time of on-site evaluation and final diagnosis, in order to avoid misinterpretation of strips of benign mesothelial cells as inadequate for diagnosis.
  • [MeSH-major] Cysts / pathology. Mesothelioma / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Biomarkers, Tumor / analysis. Biopsy, Fine-Needle. Female. Humans. Immunohistochemistry. Middle Aged

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19813256.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  •  go-up   go-down


32. Machlenkin S, Diment J, Kashtan H: Benign cystic mesothelioma of the peritoneum. Isr Med Assoc J; 2006 Jul;8(7):511-2
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cystic mesothelioma of the peritoneum.
  • [MeSH-major] Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentIn] Isr Med Assoc J. 2006 Jul;8(7):501-2 [16889169.001]
  • (PMID = 16889174.001).
  • [ISSN] 1565-1088
  • [Journal-full-title] The Israel Medical Association journal : IMAJ
  • [ISO-abbreviation] Isr. Med. Assoc. J.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Israel
  •  go-up   go-down


33. Søreide JA, Søreide K, Körner H, Søiland H, Greve OJ, Gudlaugsson E: Benign peritoneal cystic mesothelioma. World J Surg; 2006 Apr;30(4):560-6
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign peritoneal cystic mesothelioma.
  • BACKGROUND: Benign peritoneal cystic mesothelioma (BPCM) is a rare tumor of unknown origin, most frequently encountered in women of reproductive age.
  • Etiology is unknown; definitions and terminology are confusing, and preoperative diagnosis is difficult.
  • [MeSH-major] Mesothelioma, Cystic / surgery. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Aged. Biopsy. Diagnosis, Differential. Female. Follow-Up Studies. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery. Peritoneum / diagnostic imaging. Peritoneum / pathology. Peritoneum / surgery. Reoperation. Tomography, X-Ray Computed

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Am J Gastroenterol. 1995 Jul;90(7):1165-7 [7541936.001]
  • [Cites] South Med J. 1989 Dec;82(12):1579-80 [2595430.001]
  • [Cites] Med Pediatr Oncol. 1992;20(2):169-71 [1734224.001]
  • [Cites] Aust N Z J Obstet Gynaecol. 2002 Nov;42(5):552-4 [12495110.001]
  • [Cites] Tumori. 2003 Jan-Feb;89(1):31-5 [12729358.001]
  • [Cites] Indian J Gastroenterol. 1998 Oct-Dec;17(4):156-7 [9795511.001]
  • [Cites] Semin Oncol. 1981 Sep;8(3):313-20 [7280715.001]
  • [Cites] Mayo Clin Proc. 1982 Oct;57(10):634-8 [7121070.001]
  • [Cites] Surg Today. 2000;30(1):98-100 [10648095.001]
  • [Cites] Pediatr Pathol. 1988;8(3):321-9 [3174512.001]
  • [Cites] Diagn Cytopathol. 1989;5(1):14-21 [2656144.001]
  • [Cites] Cancer. 1981 Jul 1;48(1):134-9 [7237380.001]
  • [Cites] Acta Pathol Jpn. 1985 Jul;35(4):989-93 [4072681.001]
  • [Cites] Surg Endosc. 2002 Jan;16(1):220 [11961660.001]
  • [Cites] Acta Cytol. 2003 May-Jun;47(3):517-8 [12789944.001]
  • [Cites] Eur J Surg. 1992 Aug;158(8):451-3 [1356488.001]
  • [Cites] Arch Surg. 1990 Nov;125(11):1477-81 [2241560.001]
  • [Cites] APMIS. 1988 Feb;96(2):123-7 [3345257.001]
  • [Cites] Surg Laparosc Endosc. 1995 Apr;5(2):157-60 [7773468.001]
  • [Cites] Cancer. 1975 Jan;35(1):165-75 [1109769.001]
  • [Cites] J Occup Environ Med. 2004 Jan;46(1):84-9 [14724482.001]
  • [Cites] Radiology. 1989 Feb;170(2):333-7 [2643136.001]
  • [Cites] Cancer. 1980 May 1;45(9):2395-9 [7379036.001]
  • [Cites] Z Gastroenterol. 2003 Apr;41(4):329-32 [12695939.001]
  • [Cites] Semin Diagn Pathol. 1991 Nov;8(4):277-89 [1759060.001]
  • [Cites] Am J Clin Pathol. 1981 Nov;76(5):627-35 [7293978.001]
  • [Cites] Eur J Surg Oncol. 2002 Mar;28(2):192-5 [11884057.001]
  • [Cites] Cancer. 1982 Oct 15;50(8):1615-22 [7116294.001]
  • [Cites] J Surg Oncol. 2002 Apr;79(4):243-51 [11920782.001]
  • [Cites] Cancer. 1989 Sep 15;64(6):1336-46 [2766227.001]
  • [Cites] Surgery. 1979 Oct;86(4):556-60 [483165.001]
  • [Cites] Cancer. 1979 Aug;44(2):692-8 [476578.001]
  • [Cites] Dig Surg. 2000;17(4):323-8 [11053936.001]
  • [Cites] J Clin Pathol. 1993 Sep;46(9):867-8 [8227441.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1990;417(5):443-7 [2122588.001]
  • [Cites] Hum Pathol. 2003 Apr;34(4):369-74 [12733118.001]
  • [Cites] Cancer. 2005 Feb 15;103(4):839-49 [15637690.001]
  • [Cites] Eur J Surg Oncol. 1997 Oct;23(5):461-2 [9393582.001]
  • [Cites] Pathol Res Pract. 1986 Dec;181(6):767-73 [2436202.001]
  • [Cites] Arch Pathol Lab Med. 1996 Oct;120(10):959-66 [12046609.001]
  • [Cites] Abdom Imaging. 1998 Sep-Oct;23 (5):502-4 [9841063.001]
  • [Cites] Clin Radiol. 1993 Jul;48(1):66-7 [8370225.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2002 Jan;14(1):77-80 [11782579.001]
  • [Cites] J Gastroenterol. 1996 Dec;31(6):868-74 [9027654.001]
  • [Cites] J Obstet Gynaecol Can. 2002 Mar;24(3):246-7 [12196875.001]
  • (PMID = 16547615.001).
  • [ISSN] 0364-2313
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  •  go-up   go-down


34. Kao SC, Reid G, Lee K, Vardy J, Clarke S, van Zandwijk N: Malignant mesothelioma. Intern Med J; 2010 Nov;40(11):742-50
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant mesothelioma.
  • Malignant mesothelioma (MM) is an aggressive tumour that commonly affects the mesothelial surfaces of the pleural and peritoneal cavities, and occasionally, the tunica vaginalis and the pericardium.
  • Diagnosis of MM can be difficult.
  • Definitive pathological diagnosis is required and it often requires an experienced pathologist to differentiate MM from other benign or malignant processes.
  • [MeSH-major] Asbestos / toxicity. Environmental Exposure / adverse effects. Mesothelioma / epidemiology. Mesothelioma / etiology

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Asbestos.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • Hazardous Substances Data Bank. ASBESTOS .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] © 2010 The Authors. Internal Medicine Journal © 2010 Royal Australasian College of Physicians.
  • (PMID = 20298508.001).
  • [ISSN] 1445-5994
  • [Journal-full-title] Internal medicine journal
  • [ISO-abbreviation] Intern Med J
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] Australia
  • [Chemical-registry-number] 1332-21-4 / Asbestos
  •  go-up   go-down


35. Stroescu C, Negulescu R, Herlea V, David L, Ivanov B, Nitipir C, Popescu I: [Recurrent benign cystic peritoneal mesothelioma]. Chirurgia (Bucur); 2008 Nov-Dec;103(6):715-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Recurrent benign cystic peritoneal mesothelioma].
  • [Transliterated title] Mezoteliom multichistic peritoneal recidivat.
  • The benign cystic peritoneal mesothelioma (BCPM) is a rare neoplasm affecting mainly females at reproductive age.
  • The clinical manifestations are insidious, uncharacteristic; the benign cystic peritoneal mesothelioma is often discovered during a surgical procedure addressing another condition.
  • There are no long term studies dictating a single therapeutic attitude but a high risk of local recurrences and the possibility of transformation into malignant mesothelioma have lead to the current tendency towards an aggressive treatment of the tumor.
  • We present the case of a recurrent benign cystic peritoneal mesothelioma in a 40 years old female patient, emphasizing the therapeutic approach and the role of radical surgery in the treatment of BPCM.
  • [MeSH-major] Mesothelioma, Cystic / surgery. Neoplasm Recurrence, Local / surgery. Peritoneal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19274921.001).
  • [ISSN] 1221-9118
  • [Journal-full-title] Chirurgia (Bucharest, Romania : 1990)
  • [ISO-abbreviation] Chirurgia (Bucur)
  • [Language] rum
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Romania
  •  go-up   go-down


36. Assaly M, Bongiovanni M, Kumar N, Egger JF, Pelte MF, Genevay M, Finci V, Tschanz E, Pache JC: Cytology of benign multicystic peritoneal mesothelioma in peritoneal washings. Cytopathology; 2008 Aug;19(4):224-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cytology of benign multicystic peritoneal mesothelioma in peritoneal washings.
  • OBJECTIVE: To describe the cytological aspect of peritoneal washings in benign multicystic peritoneal mesothelioma (BMPM).
  • METHODS: Three peritoneal washing specimens stained by standard cytological and histological procedures and analysed by light microscopy.
  • RESULTS: The specimens showed an abundance of monomorphous mesothelial cells devoid of atypia or mitoses.
  • The mesothelial cells were calretinin positive.
  • CONCLUSION: The combination of cytology of the peritoneal washing, histology (cell block and surgical specimen) and clinical history allow differentiation of BMPM from other cystic lesions (cystic lymphangioma and malignant mesothelioma).
  • [MeSH-major] Immunohistochemistry / methods. Mesothelioma, Cystic / pathology. Neoplasms / pathology. Neoplasms, Cystic, Mucinous, and Serous / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Diagnosis, Differential. Female. Humans. Microscopy / methods. Middle Aged. Rare Diseases

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18476992.001).
  • [ISSN] 1365-2303
  • [Journal-full-title] Cytopathology : official journal of the British Society for Clinical Cytology
  • [ISO-abbreviation] Cytopathology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  •  go-up   go-down


37. Nagano K, Umeda Y, Senoh H, Gotoh K, Arito H, Yamamoto S, Matsushima T: Carcinogenicity and chronic toxicity in rats and mice exposed by inhalation to 1,2-dichloroethane for two years. J Occup Health; 2006 Nov;48(6):424-36
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The 2-yr exposure to DCE produced a dose-dependent increase in incidences of benign and malignant tumors, including subcutaneous fibroma, mammary gland fibroadenoma and peritoneal mesothelioma in male rats; subcutaneous fibroma and mammary gland adenoma, fibroadenoma and adenocarcinoma in female rats; and bronchiolo-alveolar adenoma and carcinoma, endometrial stromal polyp, mammary gland adenocarcinoma and hepatocellular adenoma in female mice.

  • MedlinePlus Health Information. consumer health - Occupational Health.
  • Hazardous Substances Data Bank. 1,2-DICHLOROETHANE .
  • Hazardous Substances Data Bank. DICHLOROETHANE .
  • Mouse Genome Informatics (MGI). Mouse Genome Informatics (MGI) .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17179635.001).
  • [ISSN] 1341-9145
  • [Journal-full-title] Journal of occupational health
  • [ISO-abbreviation] J Occup Health
  • [Language] eng
  • [Publication-type] Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Carcinogens; 0 / Ethylene Dichlorides; 55163IJI47 / ethylene dichloride
  •  go-up   go-down


38. Tangjitgamol S, Erlichman J, Northrup H, Malpica A, Wang X, Lee E, Kavanagh JJ: Benign multicystic peritoneal mesothelioma: cases reports in the family with diverticulosis and literature review. Int J Gynecol Cancer; 2005 Nov-Dec;15(6):1101-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma: cases reports in the family with diverticulosis and literature review.
  • We report on benign multicystic peritoneal mesothelioma in two siblings whose family had a history of multiple familial diseases including diverticulosis.
  • [MeSH-major] Mesothelioma, Cystic / genetics. Mesothelioma, Cystic / therapy. Peritoneal Neoplasms / genetics. Peritoneal Neoplasms / therapy

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16343188.001).
  • [ISSN] 1048-891X
  • [Journal-full-title] International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
  • [ISO-abbreviation] Int. J. Gynecol. Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Antineoplastic Agents, Hormonal
  • [Number-of-references] 29
  •  go-up   go-down


39. Wu M, Sun Y, Li G, Desman G, Wang B, Gil J, Burstein DE: Immunohistochemical detection of XIAP in mesothelium and mesothelial lesions. Am J Clin Pathol; 2007 Nov;128(5):783-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Immunohistochemical detection of XIAP in mesothelium and mesothelial lesions.
  • We examined benign and malignant mesothelial tissue samples for the presence of X-linked inhibitor of apoptosis protein (XIAP), a potent constituent of the inhibitor of apoptosis family of caspase inhibitors.
  • We subjected 55 sections (31 malignant mesotheliomas, 2 well-differentiated peritoneal mesotheliomas, 13 pleural mesothelial hyperplasias, and 9 benign mesothelial tissues) from archival formalin-fixed, paraffin-embedded surgical tissue blocks to citrate-based antigen retrieval and then incubated them with monoclonal anti-XIAP (clone 48, dilution 1:250; BD Biosciences, San Jose, CA) at 4 degrees C for 72 hours and developed them using EnVision-Plus reagents (DAKO, Carpinteria, CA) and diaminobenzidine as the chromogen.
  • All 9 normal mesothelial samples were negative for XIAP.
  • Of 13 mesothelial hyperplasias, 1 (8%) was weakly positive in fewer than 10% of cells, as was 1 of 2 well-differentiated peritoneal mesotheliomas.
  • XIAP immunostaining, when strong, allows for distinction of malignant from benign and hyperplastic mesothelial cell populations and is a potentially useful immunodiagnostic marker in small samples and morphologically controversial cases.
  • Elevated expression of XIAP could contribute to tumorigenesis in mesothelioma.
  • [MeSH-major] Biomarkers, Tumor / analysis. Epithelium / chemistry. Immunohistochemistry / methods. Mesothelioma / chemistry. Peritoneal Neoplasms / chemistry. Precancerous Conditions / chemistry. X-Linked Inhibitor of Apoptosis Protein / analysis

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17951200.001).
  • [ISSN] 0002-9173
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / X-Linked Inhibitor of Apoptosis Protein; 0 / XIAP protein, human
  •  go-up   go-down


40. Limone A, Maier J, Chiantera V, Elezkurtaj S, Foss HD, Schneider A: Laparoscopic excision of a benign peritoneal cystic mesothelioma. Arch Gynecol Obstet; 2010 Mar;281(3):577-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic excision of a benign peritoneal cystic mesothelioma.
  • Benign cystic peritoneal mesothelioma is a rare tumor and most commonly occurs in women in the reproductive age group.
  • We present a rare case of a postmenopausal woman with benign peritoneal cystic mesothelioma removed at laparoscopy.
  • [MeSH-major] Laparoscopy. Mesothelioma, Cystic / surgery. Peritoneal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19669775.001).
  • [ISSN] 1432-0711
  • [Journal-full-title] Archives of gynecology and obstetrics
  • [ISO-abbreviation] Arch. Gynecol. Obstet.
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] Germany
  •  go-up   go-down


41. Pitta X, Andreadis E, Ekonomou A, Papachristodoulou A, Tziouvaras C, Papapaulou L, Sapidis N, Chrisidis T: Benign multicystic peritoneal mesothelioma: a case report. J Med Case Rep; 2010;4:385
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma: a case report.
  • INTRODUCTION: We report the case of a patient with a benign multicystic peritoneal mesothelioma and describe its appearance on computed tomography scans and ultrasonography, in correlation with gross clinical and pathological findings.
  • Pathological analysis showed a benign multicystic peritoneal mesothelioma.
  • CONCLUSIONS: Benign multicystic peritoneal mesothelioma is a rare lesion with a non-specific appearance on imaging.
  • Its diagnosis always requires pathological analysis.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21114811.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2999614
  •  go-up   go-down


42. Asghar S, Qureshi N, Awan A: Benign mesothelioma of peritoneum presenting as a pelvic mass. J Coll Physicians Surg Pak; 2008 Nov;18(11):723-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign mesothelioma of peritoneum presenting as a pelvic mass.
  • A large solitary multiloculated pelvic cyst in a 40-year-old woman with chronic pelvic pain was diagnosed to be a Multicystic Benign Mesothelioma (MBM) of peritoneum at laparotomy.
  • Operative findings showed dense adhesions between uterus and bladder anteriorly, small intestines and pouch of Douglas posteriorly, a right ovarian cyst cm containing clear serous fluid and two nodular deposits were seen in the pouch of Douglas, small multiple deposits was found over the mesentery of small intestine and parietal peritoneum.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Ovarian Neoplasms / diagnosis. Pelvic Neoplasms / diagnosis. Pelvic Pain / diagnosis. Peritoneal Neoplasms / diagnosis

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • MedlinePlus Health Information. consumer health - Pelvic Pain.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18983801.001).
  • [ISSN] 1022-386X
  • [Journal-full-title] Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
  • [ISO-abbreviation] J Coll Physicians Surg Pak
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Pakistan
  •  go-up   go-down


43. Neumann V, Löseke S, Tannapfel A: [Medical insurance aspects of peritoneal tumors with particular attention to peritoneal mesotheliomas]. Med Klin (Munich); 2009 Oct 15;104(10):765-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Medical insurance aspects of peritoneal tumors with particular attention to peritoneal mesotheliomas].
  • Malignant peritoneal mesotheliomas arise mainly in male patients and the median age of initial diagnosis is about 56 years.
  • Epitheloid subtype predominates in peritoneal mesotheliomas.
  • Asbestos exposure is the best-known and most common risk factor associated with the development of both pleural and peritoneal mesotheliomas and, therefore, about 90% of cases can be assessed as asbestos-associated.
  • Patients with peritoneal mesotheliomas have distinctly higher asbestos burden of the lungs than patients with pleural mesotheliomas.
  • The mean latency period between exposure and diagnosis of peritoneal mesothelioma ranges from 35 to 40 years and is comparable to that of pleural mesothelioma.
  • Mesothelioma of the tunica vaginalis testis also belongs to the group of peritoneal mesotheliomas.
  • No significant evidence exists for the classification of well-differentiated papillary mesothelioma, solitary fibrous tumor, adenomatoid tumor, primary peritoneal serous borderline tumor, and benign multicystic mesothelioma as asbestos-associated tumors.
  • [MeSH-major] Asbestosis / epidemiology. Mesothelioma / epidemiology. National Health Programs / statistics & numerical data. Peritoneal Neoplasms / epidemiology
  • [MeSH-minor] Biopsy. Causality. Cross-Sectional Studies. Female. Germany. Humans. Insurance, Accident / legislation & jurisprudence. Insurance, Accident / statistics & numerical data. Male. Middle Aged. Peritoneum / pathology. Pleural Neoplasms / classification. Pleural Neoplasms / epidemiology. Pleural Neoplasms / etiology. Pleural Neoplasms / pathology. Risk Factors. Workers' Compensation / legislation & jurisprudence. Workers' Compensation / statistics & numerical data

  • MedlinePlus Health Information. consumer health - Asbestos.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Ind Med. 1960 Oct;17:260-71 [13782506.001]
  • [Cites] Arch Pathol Lab Med. 2005 Mar;129(3):403-6 [15737040.001]
  • [Cites] Environ Res. 1984 Dec;35(2):531-51 [6391911.001]
  • [Cites] Hematol Oncol Clin North Am. 2005 Dec;19(6):1067-87, vi [16325124.001]
  • [Cites] Am J Surg Pathol. 1990 Mar;14(3):230-9 [2305929.001]
  • [Cites] Ann Oncol. 2007 Jun;18(6):985-90 [17030547.001]
  • [Cites] Am J Surg Pathol. 1995 Oct;19(10):1124-37 [7573671.001]
  • [Cites] Am J Clin Oncol. 2008 Feb;31(1):49-54 [18376228.001]
  • [Cites] Br J Ind Med. 1983 May;40(2):145-52 [6299326.001]
  • [Cites] Q J Med. 1976 Jul;45(179):427-49 [948545.001]
  • [Cites] Am J Gastroenterol. 1981 Apr;75(4):311-3 [7258177.001]
  • [Cites] J Environ Pathol Toxicol Oncol. 1996;15(2-4):191-4 [9216805.001]
  • [Cites] Cancer. 1981 Jul 1;48(1):134-9 [7237380.001]
  • [Cites] Environ Health. 2008 Jan 24;7:4 [18218073.001]
  • [Cites] Histopathology. 1991 Dec;19(6):515-22 [1786936.001]
  • [Cites] Am J Respir Crit Care Med. 2008 Sep 15;178(6):624-9 [18556631.001]
  • [Cites] Ultrastruct Pathol. 2002 Nov-Dec;26(6):355-63 [12537760.001]
  • [Cites] Am J Ind Med. 1988;14(3):331-9 [3189349.001]
  • [Cites] Histopathology. 2008 Jun;52(7):824-30 [18494612.001]
  • [Cites] Am J Clin Pathol. 2005 May;123(5):724-37 [15981812.001]
  • [Cites] Am J Surg Pathol. 2001 Oct;25(10):1304-9 [11688466.001]
  • [Cites] Int J Urol. 2008 Jun;15(6):560-1 [18489651.001]
  • [Cites] Chest. 1980 Feb;77(2):133-7 [7353405.001]
  • [Cites] Pathologe. 1999 May;20(3):169-76 [10412176.001]
  • [Cites] Am J Pathol. 1995 Feb;146(2):344-56 [7856747.001]
  • [Cites] Cancer. 1988 May 15;61(10):2019-21 [3282640.001]
  • [Cites] Am J Surg Pathol. 1988 Oct;12(10):737-46 [3421410.001]
  • [Cites] Nat Med. 1997 Aug;3(8):908-12 [9256284.001]
  • [Cites] Hum Pathol. 1977 Jan;8(1):83-94 [844856.001]
  • [Cites] Swiss Surg. 2003;9(6):311-4 [14725101.001]
  • [Cites] Zentralbl Chir. 2001 Mar;126(3):229-32 [11301890.001]
  • [Cites] Adv Anat Pathol. 2006 Jan;13(1):16-25 [16462153.001]
  • [Cites] Histopathology. 2009 Jan;54(1):55-68 [19054156.001]
  • [Cites] Cancer. 1998 Dec 15;83(12):2437-46 [9874447.001]
  • [Cites] Am J Surg Pathol. 2000 Sep;24(9):1183-200 [10976692.001]
  • [Cites] Histopathology. 2002 Mar;40(3):237-44 [11895489.001]
  • [Cites] J Occup Environ Med. 2003 Apr;45(4):451-5 [12708149.001]
  • [Cites] Am J Epidemiol. 2004 Jan 15;159(2):107-12 [14718210.001]
  • [Cites] Cancer. 1996 Apr 1;77(7):1379-85 [8608519.001]
  • [Cites] Pathologe. 1989 Mar;10(2):114-7 [2717537.001]
  • [Cites] Arch Pathol Lab Med. 2007 Jan;131(1):138-44 [17227115.001]
  • [Cites] Curr Opin Pulm Med. 1999 Sep;5(5):326-31 [10461539.001]
  • [Cites] MMWR Morb Mortal Wkly Rep. 2009 Apr 24;58(15):393-6 [19390506.001]
  • [Cites] Gynecol Oncol. 2005 Jul;98(1):161-7 [15894368.001]
  • [Cites] Int J Cancer. 1987 Jan 15;39(1):10-7 [3025107.001]
  • [Cites] J Surg Oncol. 2008 Sep 15;98(4):268-72 [18726890.001]
  • [Cites] J Surg Oncol. 2002 Apr;79(4):243-51 [11920782.001]
  • [Cites] Occup Environ Med. 1994 Dec;51(12):804-11 [7849863.001]
  • [Cites] Cancer. 1989 Sep 15;64(6):1336-46 [2766227.001]
  • [Cites] Am J Pathol. 1981 Mar;102(3):314-23 [7212016.001]
  • [Cites] Int Arch Occup Environ Health. 2001 Aug;74(6):383-95 [11563601.001]
  • [Cites] Cancer. 1975 Oct;36(4):1381-5 [1175135.001]
  • [Cites] Soz Praventivmed. 1982 Oct;27(5):220-2 [7158050.001]
  • [Cites] Occup Environ Med. 2007 Dec;64(12):839-42 [17567726.001]
  • [Cites] Virchows Arch A Pathol Anat Histopathol. 1990;417(5):443-7 [2122588.001]
  • [Cites] Cancer Sci. 2006 Apr;97(4):292-5 [16630121.001]
  • [Cites] Chest. 1993 Apr;103(4 Suppl):373S-376S [8462328.001]
  • [Cites] Am J Surg Pathol. 1992 May;16(5):467-75 [1599025.001]
  • [Cites] Thorax. 1997 Jun;52(6):507-12 [9227715.001]
  • [Cites] World J Surg. 2006 Apr;30(4):560-6 [16547615.001]
  • [Cites] Chirurg. 2000 Aug;71(8):877-86 [11013806.001]
  • [Cites] Aktuelle Urol. 2006 Jul;37(4):281-3 [16878282.001]
  • [Cites] Am J Surg Pathol. 2008 Nov;32(11):1627-42 [18753943.001]
  • [Cites] Br J Dis Chest. 1983 Oct;77(4):321-43 [6357260.001]
  • [Cites] Adv Anat Pathol. 2009 Jan;16(1):62-4 [19098468.001]
  • [Cites] Environ Health Perspect. 1983 Nov;53:121-30 [6662082.001]
  • (PMID = 19856150.001).
  • [ISSN] 1615-6722
  • [Journal-full-title] Medizinische Klinik (Munich, Germany : 1983)
  • [ISO-abbreviation] Med. Klin. (Munich)
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article; Review
  • [Publication-country] Germany
  • [Number-of-references] 76
  •  go-up   go-down


44. Hasteh F, Lin GY, Weidner N, Michael CW: The use of immunohistochemistry to distinguish reactive mesothelial cells from malignant mesothelioma in cytologic effusions. Cancer Cytopathol; 2010 Apr 25;118(2):90-6
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The use of immunohistochemistry to distinguish reactive mesothelial cells from malignant mesothelioma in cytologic effusions.
  • BACKGROUND: The distinction of benign from malignant mesothelial proliferations in cytologic specimens can be problematic.
  • METHODS: Archival paraffin-embedded cell blocks of pleural and peritoneal fluids from 52 patients with malignant mesothelioma (MM) and 64 patients with reactive mesothelial hyperplasia (MH) were retrieved.
  • EMA was positive in 9% (6 of 64) of benign and 100% (52 of 52) of malignant cases (P < .001).
  • GLUT-1 was positive in 12% (5 of 43) of benign and 47% (7 of 15) of malignant cases.
  • Ki67 showed strong nuclear positivity in >40% of mesothelial cells in 9% (6 of 64) of benign and 16% (8 of 49) of malignant cases (P = .38).
  • p53 showed strong nuclear positivity in 2% (1 of 46) of benign and 47% (7 of 15) of malignant cases (P < .001).
  • Likewise, strong membranous positivity for GLUT-1 and/or strong nuclear staining for p53 favors a mesothelioma.
  • [MeSH-major] Ascitic Fluid / metabolism. Epithelium / pathology. Immunohistochemistry. Mesothelioma / diagnosis. Pleural Effusion / metabolism
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Biomarkers / metabolism. Desmin / analysis. Excitatory Amino Acid Transporter 2 / analysis. Female. Humans. Hyperplasia / pathology. Male. Middle Aged. Mucin-1 / analysis. Tumor Suppressor Protein p53 / analysis


45. Hansson M, Zendehrokh N, Ohyashiki J, Ohyashiki K, Westman UB, Roos G, Dejmek A: Telomerase activity in effusions: a comparison between telomere repeat amplification protocol in situ and conventional telomere repeat amplification protocol assay. Arch Pathol Lab Med; 2008 Dec;132(12):1896-902
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONTEXT: We previously found telomere repeat amplification protocol (TRAP) in situ helpful in the diagnosis of malignancy in effusions, whereas varying sensitivities and specificities for malignancy were reported by investigators using extract-based TRAP.
  • Five of 7 benign effusions were negative; in 2 of 7, mesothelial cells showed weak reactivity.
  • The relative telomerase activities were 33.1 to 72.7 with a considerable overlap between malignant (48 +/- 9, mean +/- SD) and benign (43 +/- 9) cases.
  • CONCLUSIONS: The TRAP in situ results correlated to final diagnoses, whereas the cell lysate-based TRAP assay did not differentiate between malignant and benign cases.
  • [MeSH-minor] Humans. Mesothelioma / diagnosis. Mesothelioma / enzymology. Mesothelioma / pathology. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / enzymology. Peritoneal Neoplasms / pathology. Pleural Neoplasms / diagnosis. Pleural Neoplasms / enzymology. Pleural Neoplasms / pathology. Retrospective Studies. Sensitivity and Specificity

  • MedlinePlus Health Information. consumer health - Pericardial Disorders.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19061286.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.7.49 / Telomerase
  •  go-up   go-down


46. Uzüm N, Ozçay N, Ataoğlu O: Benign multicystic peritoneal mesothelioma. Turk J Gastroenterol; 2009 Jun;20(2):138-41
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma.
  • Benign multicystic peritoneal mesothelioma is a rare tumor that occurs mainly in women in their reproductive age.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Mesothelioma, Cystic / surgery. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / surgery

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19530048.001).
  • [ISSN] 2148-5607
  • [Journal-full-title] The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
  • [ISO-abbreviation] Turk J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Turkey
  •  go-up   go-down


47. Ng JW, Lau RL, Ng WF: Benign multicystic peritoneal mesothelioma: a diagnostic challenge. ANZ J Surg; 2006 May;76(5):421-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma: a diagnostic challenge.
  • [MeSH-major] Hernia, Inguinal / pathology. Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology. Pseudomyxoma Peritonei / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [CommentOn] ANZ J Surg. 2005 Jul;75(7):619-20 [15972062.001]
  • [ErratumIn] ANZ J Surg. 2006 Jul;76(7):651
  • (PMID = 16768710.001).
  • [ISSN] 1445-1433
  • [Journal-full-title] ANZ journal of surgery
  • [ISO-abbreviation] ANZ J Surg
  • [Language] eng
  • [Publication-type] Case Reports; Comment; Letter
  • [Publication-country] Australia
  •  go-up   go-down


48. Vintman L, Nielsen S, Berner A, Reich R, Davidson B: Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells. Cancer; 2005 Jun 1;103(11):2427-33
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mitogen-activated protein kinase expression and activation does not differentiate benign from malignant mesothelial cells.
  • BACKGROUND: In vitro studies of malignant mesothelioma (MM) cells have suggested activation of mitogen-activated protein kinase (MAPK) in response to asbestos exposure.
  • Pan-p38 expression levels also were higher in peritoneal MM specimens (P = 0.019).
  • The similar values in these two cell types suggest that MAPK may not be involved in the transformation of benign to malignant mesothelium, thus bringing into question the validity of using MAPKs as molecular therapeutic targets in patients with MM.
  • [MeSH-major] JNK Mitogen-Activated Protein Kinases / metabolism. Mesothelioma / enzymology. Mitogen-Activated Protein Kinase 3 / metabolism. Mitogen-Activated Protein Kinase Kinases / metabolism. p38 Mitogen-Activated Protein Kinases / metabolism

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTAC Assay Portal. NCI CPTAC Assay Portal .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 15830375.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] EC 2.7.11.24 / JNK Mitogen-Activated Protein Kinases; EC 2.7.11.24 / Mitogen-Activated Protein Kinase 3; EC 2.7.11.24 / p38 Mitogen-Activated Protein Kinases; EC 2.7.12.2 / MAP Kinase Kinase 4; EC 2.7.12.2 / Mitogen-Activated Protein Kinase Kinases
  •  go-up   go-down


49. Bernstein EM, Tate A, Silasi DA, Rutherford T: Benign multicystic mesothelioma: a case report of three sisters. Rare Tumors; 2009;1(2):e46
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic mesothelioma: a case report of three sisters.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21139925.001).
  • [ISSN] 2036-3613
  • [Journal-full-title] Rare tumors
  • [ISO-abbreviation] Rare Tumors
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
  • [Other-IDs] NLM/ PMC2994461
  • [Keywords] NOTNLM ; benign multicystic mesothelioma / genetic or familial association / gynecology / multilocular inclusion cyst. / oncology / peritoneal inclusion cyst / peritoneal mesothelioma / tumors
  •  go-up   go-down


50. de Keizer B, Arsos G, Smit JW, Lam MG, Rinkes IH, Goldschmeding R, van Isselt JW: I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer. Thyroid; 2008 Mar;18(3):369-71
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer.
  • Focal I-131 accumulation is generally a reliable indicator of functioning normal thyroid tissue or a differentiated thyroid cancer metastasis.
  • We report a case of focal I-131 accumulation in a benign cystic mesothelioma in a patient with follicular thyroid cancer.
  • [MeSH-major] Adenocarcinoma, Follicular / radionuclide imaging. Iodine Radioisotopes. Mesothelioma, Cystic / radionuclide imaging. Peritoneal Neoplasms / radionuclide imaging. Thyroid Nodule / radionuclide imaging. Tomography, Emission-Computed, Single-Photon / adverse effects
  • [MeSH-minor] Adult. Humans. Male. Neoplasms / complications. Neoplasms / pathology. Neoplasms / radionuclide imaging. Neoplasms, Second Primary / pathology. Neoplasms, Second Primary / radiography. Tissue Distribution

  • Genetic Alliance. consumer health - Thyroid cancer, follicular.
  • Genetic Alliance. consumer health - Thyroid Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18298317.001).
  • [ISSN] 1050-7256
  • [Journal-full-title] Thyroid : official journal of the American Thyroid Association
  • [ISO-abbreviation] Thyroid
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Iodine Radioisotopes
  •  go-up   go-down


51. Hanley KZ, Facik MS, Bourne PA, Yang Q, Spaulding BO, Bonfiglio TA, Xu H: Utility of anti-L523S antibody in the diagnosis of benign and malignant serous effusions. Cancer; 2008 Feb 25;114(1):49-56
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Utility of anti-L523S antibody in the diagnosis of benign and malignant serous effusions.
  • BACKGROUND: Immunohistochemistry is helpful in distinguishing metastatic carcinoma from atypical mesothelial cells; however, it is not useful in differentiating atypical mesothelial cells from malignant mesothelial cells.
  • Using a mouse monoclonal antibody (L523S) against KOC, KOC expression was investigated in malignant tumors and reactive mesothelial cells in serous effusions.
  • METHODS: Seventy-six cases with paraffin-embedded pleural, pericardial, and peritoneal serous effusion cell blocks including 60 malignant serous effusions (11 malignant pleural mesotheliomas and 49 metastatic carcinomas) and benign pleural effusions (14 cases with reactive mesothelial cells and 2 cases with atypical cells with uncertain significance) were selected for immunohistochemical analysis with L523S, calretinin, and CK5/6.
  • The associated reactive mesothelial cells were negative for KOC but positive for calretinin and CK5/6.
  • In addition, 16 cases that were originally diagnosed either as pleural effusions with reactive mesothelial cells (14) or atypical cells with uncertain significance (2) were also tested for KOC expression.
  • Interestingly, 3 of 16 cases exhibited various degrees of positivity for KOC, 2 of which were diagnosed as lung adenocarcinoma with a recurrence after tumor resection and 1 as malignant pleural mesothelioma.
  • CONCLUSIONS: Anti-L523S antibody is a useful marker for the detection of malignant cells in serous effusions and it can have significant utility in differentiating reactive mesothelial cells from malignant mesothelioma and metastatic carcinoma in combination with calretinin and CK5/6 staining.
  • [MeSH-major] Biomarkers, Tumor / analysis. Mesothelioma / diagnosis. Neoplasm Proteins / analysis. Pleural Effusion / diagnosis. Pleural Effusion, Malignant / diagnosis. RNA-Binding Proteins / analysis
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Ascitic Fluid / chemistry. Calbindin 2. Female. Humans. Immunohistochemistry. Male. Middle Aged. Neoplasm Metastasis. Pericardial Effusion / chemistry. S100 Calcium Binding Protein G / analysis

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2007 American Cancer Society
  • (PMID = 18098206.001).
  • [ISSN] 0008-543X
  • [Journal-full-title] Cancer
  • [ISO-abbreviation] Cancer
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CALB2 protein, human; 0 / Calb2 protein, mouse; 0 / Calbindin 2; 0 / IMP3 protein, human; 0 / Neoplasm Proteins; 0 / RNA-Binding Proteins; 0 / S100 Calcium Binding Protein G
  •  go-up   go-down


52. Moore AJ, Parker RJ, Wiggins J: Malignant mesothelioma. Orphanet J Rare Dis; 2008;3:34
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Malignant mesothelioma.
  • Malignant mesothelioma is a fatal asbestos-associated malignancy originating from the lining cells (mesothelium) of the pleural and peritoneal cavities, as well as the pericardium and the tunica vaginalis.
  • Pleural malignant mesothelioma is the most common form of mesothelioma.
  • A chest wall mass, weight loss, sweating, abdominal pain and ascites (due to peritoneal involvement) are less common presentations.
  • Mesothelioma is directly attributable to occupational asbestos exposure with a history of exposure in over 90% of cases.
  • There is also evidence that mesothelioma may result from both para-occupational exposure and non-occupational "environmental" exposure.
  • Idiopathic or spontaneous mesothelioma can also occur in the absence of any exposure to asbestos, with a spontaneous rate in humans of around one per million.
  • A combination of accurate exposure history, along with examination radiology and pathology are essential to make the diagnosis.
  • Distinguishing malignant from benign pleural disease can be challenging.
  • Life expectancy in malignant mesothelioma is poor, with a median survival of about one year following diagnosis.
  • [MeSH-major] Mesothelioma / diagnosis. Mesothelioma / pathology. Pleural Neoplasms / diagnosis. Pleural Neoplasms / pathology

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Clin Cancer Res. 2006 Jul 15;12(14 Pt 1):4225-31 [16857795.001]
  • [Cites] Semin Diagn Pathol. 2006 Feb;23(1):56-60 [17044196.001]
  • [Cites] Orphanet J Rare Dis. 2006;1:44 [17090323.001]
  • [Cites] Cochrane Database Syst Rev. 2007;(1):CD005574 [17253564.001]
  • [Cites] Clin Oncol (R Coll Radiol). 2007 Apr;19(3):182-7 [17359904.001]
  • [Cites] Clin Chem. 2007 Apr;53(4):666-72 [17289801.001]
  • [Cites] J Thorac Oncol. 2006 May;1(4):289-95 [17409872.001]
  • [Cites] Exp Anim. 2007 Apr;56(2):155-9 [17460361.001]
  • [Cites] Clin Cancer Res. 2007 May 15;13(10):2928-35 [17504993.001]
  • [Cites] Curr Opin Pulm Med. 2007 Jul;13(4):339-443 [17534183.001]
  • [Cites] Radiother Oncol. 2007 Jul;84(1):18-22 [17588698.001]
  • [Cites] Oncologist. 2007 Jul;12(7):850-63 [17673616.001]
  • [Cites] Ann Oncol. 2007 Jul;18(7):1196-202 [17429100.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1366-74 [17674974.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2007 Oct 1;69(2):350-7 [17467922.001]
  • [Cites] Thorax. 2007 Nov;62 Suppl 2:ii1-ii19 [17965072.001]
  • [Cites] Eur Respir J. 2007 Nov;30(5):1021 [17978160.001]
  • [Cites] Occup Med (Lond). 2007 Dec;57(8):564-8 [17675661.001]
  • [Cites] Ann Thorac Surg. 2008 Jan;85(1):265-72; discussion 272 [18154821.001]
  • [Cites] Ann Oncol. 2008 Feb;19(2):370-3 [18156144.001]
  • [Cites] Mayo Clin Proc. 2008 Feb;83(2):235-50 [18241636.001]
  • [Cites] Ann Thorac Surg. 2008 Mar;85(3):1049-55 [18291195.001]
  • [Cites] Arch Pathol Lab Med. 2008 Mar;132(3):397-401 [18318582.001]
  • [Cites] J Thorac Cardiovasc Surg. 2008 Mar;135(3):620-6, 626.e1-3 [18329481.001]
  • [Cites] Lung Cancer. 2008 Mar;59(3):411-20 [18061303.001]
  • [Cites] Curr Opin Pulm Med. 2008 Jul;14(4):303-9 [18520263.001]
  • [Cites] Regul Toxicol Pharmacol. 2008 Oct;52(1 Suppl):S223-31 [18022298.001]
  • [Cites] Occup Med (Lond). 2005 Mar;55(2):79-87 [15757980.001]
  • [Cites] J Natl Cancer Inst. 2000 Feb 2;92(3):205-16 [10655437.001]
  • [Cites] Eur J Cardiothorac Surg. 2000 Aug;18(2):143-6 [10925221.001]
  • [Cites] J Clin Oncol. 2000 Dec 1;18(23):3912-7 [11099320.001]
  • [Cites] J Thorac Cardiovasc Surg. 2001 Oct;122(4):788-95 [11581615.001]
  • [Cites] Toxicol Lett. 2002 Feb 28;127(1-3):251-7 [12052665.001]
  • [Cites] Lung Cancer. 2002 Nov;38(2):111-21 [12399121.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2003 Mar 1;55(3):606-16 [12573747.001]
  • [Cites] Thorax. 2003 May;58 Suppl 2:ii29-38 [12728148.001]
  • [Cites] J Clin Oncol. 2003 Jul 15;21(14):2636-44 [12860938.001]
  • [Cites] Ann Diagn Pathol. 2003 Oct;7(5):321-32 [14571437.001]
  • [Cites] Lancet. 2003 Nov 15;362(9396):1612-6 [14630441.001]
  • [Cites] Radiographics. 2004 Jan-Feb;24(1):105-19 [14730040.001]
  • [Cites] Ann Oncol. 2004 Feb;15(2):257-60 [14760119.001]
  • [Cites] Thorax. 2004 Feb;59(2):144-8 [14760156.001]
  • [Cites] Chest. 2004 Feb;125(2):489-93 [14769729.001]
  • [Cites] Cochrane Database Syst Rev. 2004;(1):CD002916 [14973997.001]
  • [Cites] Int J Occup Environ Health. 2004 Jan-Mar;10(1):26-39 [15070023.001]
  • [Cites] J Thorac Cardiovasc Surg. 2004 Jul;128(1):138-46 [15224033.001]
  • [Cites] Am J Respir Crit Care Med. 2004 Aug 15;170(4):377-82 [15142871.001]
  • [Cites] Ann Oncol. 2004 Sep;15(9):1406-12 [15319247.001]
  • [Cites] Lancet. 2004 Sep 25-Oct 1;364(9440):1157-66 [15451223.001]
  • [Cites] Lancet. 2004 Sep 25-Oct 1;364(9440):1183-5 [15451229.001]
  • [Cites] Q J Med. 1976 Jul;45(179):427-49 [948545.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1982 Jan;8(1):19-25 [6174494.001]
  • [Cites] Acta Clin Belg. 1989;44(3):199-201 [2816228.001]
  • [Cites] AJR Am J Roentgenol. 1990 Mar;154(3):487-92 [2106209.001]
  • [Cites] Am J Clin Oncol. 1990 Feb;13(1):4-9 [1689538.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1991 Mar;20(3):433-8 [1995528.001]
  • [Cites] Clin Oncol (R Coll Radiol). 1991 Nov;3(6):315-7 [1720658.001]
  • [Cites] Australas Radiol. 1994 Aug;38(3):212-4 [7524472.001]
  • [Cites] Lancet. 1995 Mar 4;345(8949):535-9 [7776771.001]
  • [Cites] J Comput Assist Tomogr. 1995 May-Jun;19(3):370-4 [7790544.001]
  • [Cites] Chest. 1995 Sep;108(3):754-8 [7656629.001]
  • [Cites] Chest. 1995 Oct;108(4):1122-8 [7555126.001]
  • [Cites] Clin Oncol (R Coll Radiol). 1995;7(5):317-8 [8580058.001]
  • [Cites] Proc Natl Acad Sci U S A. 1996 Jan 9;93(1):136-40 [8552591.001]
  • [Cites] Eur Respir J. 1996 Jun;9(6):1206-10 [8804939.001]
  • [Cites] Ann Surg. 1996 Sep;224(3):288-94; discussion 294-6 [8813257.001]
  • [Cites] Thorax. 1997 Jun;52(6):507-12 [9227715.001]
  • [Cites] Eur J Cancer Prev. 1997 Apr;6(2):162-6 [9237066.001]
  • [Cites] Semin Thorac Cardiovasc Surg. 1997 Oct;9(4):367-72 [9352954.001]
  • [Cites] Thorax. 1997 Aug;52 Suppl 3:S52-7 [9381428.001]
  • [Cites] Ann Oncol. 1998 Mar;9(3):269-73 [9602260.001]
  • [Cites] Respir Med. 1998 Apr;92(4):691-2 [9659538.001]
  • [Cites] Chest. 1998 Sep;114(3):713-22 [9743156.001]
  • [Cites] Cancer Res. 1998 Oct 15;58(20):4505-9 [9788590.001]
  • [Cites] Radiology. 1999 Jan;210(1):277-81 [9885620.001]
  • [Cites] Occup Environ Med. 1999 Jan;56(1):51-8 [10341747.001]
  • [Cites] Br J Ind Med. 1960 Oct;17:260-71 [13782506.001]
  • [Cites] Br J Cancer. 2005 Feb 14;92(3):587-93 [15668716.001]
  • [Cites] Eur J Surg Oncol. 2005 Apr;31(3):314-20 [15780570.001]
  • [Cites] Cancer Res. 2005 Apr 1;65(7):2602-9 [15805256.001]
  • [Cites] Lung Cancer. 2005 Jul;49 Suppl 1:S109-11 [15950789.001]
  • [Cites] Lung Cancer. 2005 Jul;49 Suppl 1:S37-40 [15950799.001]
  • [Cites] J Clin Oncol. 2005 Oct 1;23(28):6881-9 [16192580.001]
  • [Cites] N Engl J Med. 2005 Oct 13;353(15):1564-73 [16221779.001]
  • [Cites] Eur J Cardiothorac Surg. 2006 Jan;29(1):14-9 [16343925.001]
  • [Cites] Clin Imaging. 2006 May-Jun;30(3):177-80 [16632152.001]
  • [Cites] Am J Respir Crit Care Med. 2006 May 15;173(10):1155-60 [16456138.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Jul 1;65(3):640-5 [16751058.001]
  • [Cites] Cochrane Database Syst Rev. 2006;(3):CD003880 [16856023.001]
  • (PMID = 19099560.001).
  • [ISSN] 1750-1172
  • [Journal-full-title] Orphanet journal of rare diseases
  • [ISO-abbreviation] Orphanet J Rare Dis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 93
  • [Other-IDs] NLM/ PMC2652430
  •  go-up   go-down


53. O'Connor DB, Beddy D, Aremu MA: Benign cystic mesothelioma of the appendix presenting in a woman: a case report. J Med Case Rep; 2010;4:394
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cystic mesothelioma of the appendix presenting in a woman: a case report.
  • INTRODUCTION: Benign cystic mesothelioma or peritoneal inclusion cysts are rare benign abdominal tumors usually occurring in females of reproductive age.
  • We report what is, to the best of our knowledge, the first case of a benign cystic mesothelioma complicating a presentation of acute appendicitis.
  • Histology revealed benign cystic mesothelioma.
  • CONCLUSION: We report what is, to the best of our knowledge, the first case of a benign cystic mesothelioma arising from the appendix and complicating a presentation of acute appendicitis.
  • This is a benign pathology, but recurrences are not uncommon.
  • Benign cystic mesothelioma should be included in the differential when investigating pelvic masses or abscesses associated with either appendicitis or pelvic inflammatory disease in women.

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 21129176.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3003679
  •  go-up   go-down


54. Urbańczyk K, Skotniczny K, Kuciński J, Friediger J: Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases. Pol J Pathol; 2005;56(2):81-7
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases.
  • The report presents six cases of mesothelial inclusion cysts (MIC), detected in five females (22-53 years of age) and one male (47 years old).
  • The lesions were unifocal (four cases) and multifocal (two cases), and were located on the surface of the peritoneum in the cul de sac, on the intestines, urinary bladder, uterine adnexa, also involved round ligament within the pelvis and in the inguinal canal (one patient).
  • Additionally, in one female, small cysts, free-floating in the peritoneal cavity were present.
  • Apart from MIC, three patients presented with concomitant diseases: appendicitis (two cases), peritoneal pseudomyxoma or primary ovarian carcinoma.
  • Microscopically, the majority of cysts were lined with a single layer of flattened or cuboid mesothelial cells (CK+, calretinin+).
  • Intramural proliferations and intracystic detached clumps of cells showed both mesothelial cells (without any mitotic activity and signs of atypia) and macrophages (CD68+).
  • [MeSH-major] Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16092670.001).
  • [ISSN] 1233-9687
  • [Journal-full-title] Polish journal of pathology : official journal of the Polish Society of Pathologists
  • [ISO-abbreviation] Pol J Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Poland
  •  go-up   go-down


55. Schwartz A, Peycru T, Tardat E, Dufau JP, Jarry J, Durand-Dastes F: [Peritoneal cystic mesothelioma: benign or malignant?]. J Chir (Paris); 2008 Sep-Oct;145(5):511-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Peritoneal cystic mesothelioma: benign or malignant?].
  • [MeSH-major] Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Humans. Male. Prognosis. Treatment Outcome

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19106878.001).
  • [ISSN] 0021-7697
  • [Journal-full-title] Journal de chirurgie
  • [ISO-abbreviation] J Chir (Paris)
  • [Language] fre
  • [Publication-type] Case Reports; Letter
  • [Publication-country] France
  •  go-up   go-down


56. Wheeler YY, Burroughs F, Li QK: Fine-needle aspiration of a well-differentiated papillary mesothelioma in the inguinal hernia sac: A case report and review of literature. Diagn Cytopathol; 2009 Oct;37(10):748-54
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Fine-needle aspiration of a well-differentiated papillary mesothelioma in the inguinal hernia sac: A case report and review of literature.
  • Well-differentiated papillary mesothelioma (WDPM) is an uncommon subtype of epithelioid mesothelioma.
  • In contrast to malignant epithelioid mesothelioma, WDPM has a low malignant potential and an indolent clinical course.
  • WDPM may be difficult to diagnose and differentiate from benign reactive mesothelial cells and other malignant neoplasm on cytology specimens due to the presence of papillary or tubulopapillary clusters of tumor cells.
  • We report a case of a 63-year-old Asian male with a slowly growing left inguinal hernia mass for several years and a concurrent 8 cm mass in the peritoneal wall.
  • The cytology of ultrasound-guided fine-needle aspiration (FNA) of the left inguinal hernia and peritoneal masse reveal cellular specimens with numerous individual and tubulopapillary clusters of epithelioid mesothelial cells in a background of scant hyalinized material.
  • Tumor cells show minimal cytological atypia.
  • The differential diagnoses are broad and include reactive mesothelial cells, WDPM, and other malignant neoplasm.
  • It is important to recognize this entity in the differential diagnosis, because the clinical management of WDPM is quite different from that of malignant neoplasm.
  • [MeSH-major] Hernia, Inguinal / pathology. Inguinal Canal / pathology. Mesothelioma / pathology. Peritoneal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19373910.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 26
  •  go-up   go-down


57. Husain AN, Colby TV, Ordóñez NG, Krausz T, Borczuk A, Cagle PT, Chirieac LR, Churg A, Galateau-Salle F, Gibbs AR, Gown AM, Hammar SP, Litzky LA, Roggli VL, Travis WD, Wick MR: Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group. Arch Pathol Lab Med; 2009 Aug;133(8):1317-31
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Guidelines for pathologic diagnosis of malignant mesothelioma: a consensus statement from the International Mesothelioma Interest Group.
  • CONTEXT: Malignant mesothelioma (MM) is an uncommon tumor that can be difficult to diagnose.
  • OBJECTIVE: To develop practical guidelines for the pathologic diagnosis of MM.
  • DATA SOURCES: A pathology panel was convened at the International Mesothelioma Interest Group biennial meeting (October 2006).
  • CONCLUSIONS: There was consensus opinion regarding (1) distinguishing benign from malignant mesothelial proliferations (both epithelioid and spindle cell lesions), (2) cytologic diagnosis of MM, (3) key histologic features of pleural and peritoneal MM, (4) use of histochemical and immunohistochemical stains in the diagnosis and differential diagnosis of MM, (5) differentiating epithelioid MM from various carcinomas (lung, breast, ovarian, and colonic adenocarcinomas and squamous cell and renal cell carcinomas), (6) diagnosis of sarcomatoid mesothelioma, (7) use of molecular markers in the differential diagnosis of MM, (8) electron microscopy in the diagnosis of MM, and (9) some caveats and pitfalls in the diagnosis of MM.
  • Immunohistochemical panels are integral to the diagnosis of MM, but the exact makeup of panels used is dependent on the differential diagnosis and on the antibodies available in a given laboratory.
  • The International Mesothelioma Interest Group recommends that markers have either sensitivity or specificity greater than 80% for the lesions in question.
  • [MeSH-major] Mesothelioma / diagnosis. Peritoneal Neoplasms / diagnosis. Pleural Neoplasms / diagnosis
  • [MeSH-minor] Adenocarcinoma / diagnosis. Biomarkers, Tumor / metabolism. Diagnosis, Differential. Humans

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • The Lens. Cited by Patents in .
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19653732.001).
  • [ISSN] 1543-2165
  • [Journal-full-title] Archives of pathology & laboratory medicine
  • [ISO-abbreviation] Arch. Pathol. Lab. Med.
  • [Language] eng
  • [Publication-type] Consensus Development Conference; Journal Article; Practice Guideline
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor
  • [Number-of-references] 53
  •  go-up   go-down


58. McCaffrey JC, Foo FJ, Dalal N, Siddiqui KH: Benign multicystic peritoneal mesothelioma associated with hydronephrosis and colovesical fistula formation: report of a case. Tumori; 2009 Nov-Dec;95(6):808-10
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma associated with hydronephrosis and colovesical fistula formation: report of a case.
  • We report an unusual case of benign peritoneal mesothelioma presenting in a 59-year-old woman.
  • [MeSH-major] Hydronephrosis / etiology. Intestinal Fistula / etiology. Mesothelioma / complications. Peritoneal Neoplasms / complications


59. Rekhi B, Pathuthara S, Ajit D, Kane SV: "Signet-ring" cells--a caveat in the diagnosis of a diffuse peritoneal mesothelioma occurring in a lady presenting with recurrent ascites: an unusual case report. Diagn Cytopathol; 2010 Jun;38(6):435-9
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] "Signet-ring" cells--a caveat in the diagnosis of a diffuse peritoneal mesothelioma occurring in a lady presenting with recurrent ascites: an unusual case report.
  • A diffuse peritoneal mesothelioma is a rare tumor.
  • Exfoliative cytology forms the first step in the diagnosis of mesothelioma, since most of these cases presented with effusion.
  • Despite well established cytomorphological features, a challenge exists in differentiating mesothelial cells, including reactive and malignant types from carcinoma cells and macrophages.
  • Presence of "signet-ring" cells increases the diagnostic challenge as these can be forms of benign and malignant cells.
  • Ancillary techniques like immunohistochemical (IHC) markers and ultrastructural analysis form useful adjunct in substantiating exact diagnosis.
  • We report an unusual case study of a diffuse peritoneal mesothelioma in a 57-years-old lady, with no history of asbestos exposure, presenting with recurrent ascites, diagnosed on ascitic fluid cytology and on histology as an adenocarcinoma, based upon the presence of "signet-ring" cells.
  • On review, clinicopathological correlation with IHC was helpful in forming correct diagnosis.
  • [MeSH-major] Ascites / etiology. Carcinoma, Signet Ring Cell / pathology. Diagnostic Errors. Mesothelioma / pathology. Peritoneal Neoplasms / pathology

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] (c) 2009 Wiley-Liss, Inc.
  • (PMID = 19937944.001).
  • [ISSN] 1097-0339
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


60. Pinto V, Rossi AC, Fiore MG, D'Addario V, Cicinelli E: Laparoscopic diagnosis and treatment of pelvic benign multicystic mesothelioma associated with high CA19.9 serum concentration. J Minim Invasive Gynecol; 2010 Mar-Apr;17(2):252-4
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic diagnosis and treatment of pelvic benign multicystic mesothelioma associated with high CA19.9 serum concentration.
  • We report a case of benign multicystic mesothelioma in a 20-year-old woman referred because of amenorrhea.
  • Tumor serum markers revealed an increase in CA19.9.
  • With immunohistochemistry, the tumor cells were strongly positive for cytokeratin and calretinin.
  • These aspects were suggestive of benign multicystic mesothelioma.
  • Electron microscopy confirmed the mesothelial nature of this tumor.
  • The association between benign multicystic mesothelioma and increased CA19.9 serum concentration has been described only once, in a man.
  • To our knowledge, this is the second case of benign multicystic mesothelioma associated with increased CA19.9 serum concentration and the first diagnosed in a woman.
  • In the present case, a minimally invasive laparoscopic approach enabled not only histologic diagnosis of benign multicystic mesothelioma but also its surgical treatment.
  • Although benign multicystic mesothelioma is a rare pathologic entity, it is important that sonologists include it in the differential diagnosis of diseases that manifest with ascites.
  • Furthermore, all surgeons should be aware of the macroscopic and laparoscopic appearance of the lesion, and its generally benign course.
  • [MeSH-major] CA-19-9 Antigen / blood. Laparoscopy. Mesothelioma, Cystic / pathology. Mesothelioma, Cystic / surgery. Peritoneal Neoplasms / pathology. Peritoneal Neoplasms / surgery

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2010 AAGL. Published by Elsevier Inc. All rights reserved.
  • (PMID = 20226419.001).
  • [ISSN] 1553-4650
  • [Journal-full-title] Journal of minimally invasive gynecology
  • [ISO-abbreviation] J Minim Invasive Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CA-19-9 Antigen
  •  go-up   go-down


61. Davidson B, Baekelandt M, Shih IeM: MUC4 is upregulated in ovarian carcinoma effusions and differentiates carcinoma cells from mesothelial cells. Diagn Cytopathol; 2007 Dec;35(12):756-60
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] MUC4 is upregulated in ovarian carcinoma effusions and differentiates carcinoma cells from mesothelial cells.
  • Using gene expression arrays, we recently showed that MUC4 expression is significantly higher in ovarian/primary peritoneal serous carcinoma (OC/PPC) compared to diffuse peritoneal malignant mesothelioma (DMPM).
  • We additionally studied the ability of MUC4 to differentiate between OC/PPC and reactive mesothelial cells (RMC).
  • OC/PPC effusions (n = 142) and benign reactive effusions (n = 10) were immunostained for MUC4 expression.
  • Immunoreactivity was scored in carcinoma cells and RMC and was compared with tumor cell expression in 60 previously studied primary carcinomas and solid metastases and analyzed for association with clinicopathologic parameters, including survival.
  • MUC4 was detected in carcinoma cells in 141/142 (99%) effusions, with comparable expression in peritoneal and pleural effusions.
  • The data in the present study, together with our earlier report, show that MUC4 is an excellent marker for differentiating OC/PPC from both benign and malignant mesothelial cells.
  • [MeSH-major] Ascitic Fluid / metabolism. Cystadenocarcinoma, Serous / metabolism. Mesothelioma / metabolism. Mucins / biosynthesis. Ovarian Neoplasms / metabolism. Pleural Effusion, Malignant / metabolism
  • [MeSH-minor] Age Factors. Biomarkers, Tumor / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Kaplan-Meier Estimate. Middle Aged. Mucin-4. Oligonucleotide Array Sequence Analysis. Peritoneal Neoplasms / metabolism. Peritoneal Neoplasms / pathology. Up-Regulation

  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Copyright] Copyright 2007 Wiley-Liss, Inc.
  • (PMID = 18008338.001).
  • [ISSN] 8755-1039
  • [Journal-full-title] Diagnostic cytopathology
  • [ISO-abbreviation] Diagn. Cytopathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / MUC4 protein, human; 0 / Mucin-4; 0 / Mucins
  •  go-up   go-down


62. Levy AD, Arnáiz J, Shaw JC, Sobin LH: From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation. Radiographics; 2008 Mar-Apr;28(2):583-607; quiz 621-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] From the archives of the AFIP: primary peritoneal tumors: imaging features with pathologic correlation.
  • Primary peritoneal tumors are uncommon lesions that arise from the mesothelial or submesothelial layers of the peritoneum.
  • Primary malignant mesothelioma, multicystic mesothelioma, primary peritoneal serous carcinoma, leiomyomatosis peritonealis disseminata, and desmoplastic small round cell tumor are the most prominent of these rare lesions.
  • Primary malignant mesothelioma is a highly aggressive malignancy that occurs most commonly in older men and that has a strong association with high levels of asbestos exposure.
  • It manifests most often as diffuse sheetlike or nodular thickening of the peritoneal surfaces, but it may occasionally be a localized mass.
  • Multicystic mesothelioma occurs most frequently in women and has benign or indolent biologic behavior in the majority of patients.
  • It is a multilocular cystic mass that arises from the pelvic peritoneal surfaces.
  • Primary peritoneal serous carcinoma occurs almost exclusively in women.
  • Leiomyomatosis peritonealis disseminata is a rare, benign proliferative process that also occurs exclusively in women and is characterized by multiple smooth muscle nodules throughout the peritoneum.
  • Desmoplastic small round cell tumor is a highly aggressive malignancy of unknown origin that occurs most often in the peritoneal cavity of young men.
  • This unusual group of tumors is linked together by a common site of origin and imaging manifestations that mimic those of peritoneal carcinomatosis.
  • Knowledge of the spectrum of imaging findings in this group of primary peritoneal tumors, along with their clinical and pathologic characteristics, is important in the evaluation of patients with diffuse peritoneal disease.
  • [MeSH-major] Diagnostic Imaging. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Carcinoma, Small Cell / diagnosis. Carcinoma, Small Cell / pathology. Contrast Media. Cystadenocarcinoma, Serous / diagnosis. Cystadenocarcinoma, Serous / pathology. Diagnosis, Differential. Fibrosis / diagnosis. Fibrosis / pathology. Humans. Leiomyomatosis / diagnosis. Leiomyomatosis / pathology. Mesothelioma / diagnosis. Mesothelioma / pathology. Peritoneum / anatomy & histology. Peritoneum / pathology

  • MedlinePlus Health Information. consumer health - Diagnostic Imaging.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18349460.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 55
  •  go-up   go-down


63. Saad S, Brockmann M, Maegele M: Benign peritoneal multicystic mesothelioma diagnosed and treated by laparoscopic surgery. J Laparoendosc Adv Surg Tech A; 2007 Oct;17(5):649-52
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign peritoneal multicystic mesothelioma diagnosed and treated by laparoscopic surgery.
  • Benign cystic mesothelioma is a rare pathology predominantly encountered in females.
  • The increased use of laparoscopy for abdominal pain, particularly in female patients, implies that surgeons are aware of the macro- and laparoscopic presentation of this tumor for adequate diagnosis and therapy.
  • In this paper, we present the case of a young woman with benign multicystic mesothelioma in which only laparoscopy led to the appropriate diagnosis.
  • Subsequently, the tumor was removed by laparoscopic surgery.
  • [MeSH-major] Laparoscopy / methods. Mesothelioma, Cystic / surgery. Peritoneal Neoplasms / surgery
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Diagnosis, Differential. Female. Humans

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 17907980.001).
  • [ISSN] 1092-6429
  • [Journal-full-title] Journal of laparoendoscopic & advanced surgical techniques. Part A
  • [ISO-abbreviation] J Laparoendosc Adv Surg Tech A
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


64. Wu M, Yuan S, Szporn AH, Gan L, Shtilbans V, Burstein DE: Immunocytochemical detection of XIAP in body cavity effusions and washes. Mod Pathol; 2005 Dec;18(12):1618-22
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • We performed an immunocytochemical survey of XIAP expression in cell blocks from benign and malignant body cavity effusions and washes.
  • In all, 116 alcohol-fixed, formalin postfixed paraffin-embedded cell block specimens from 82 pleural effusions, 22 ascites, 11 pelvic/peritoneal washes and one pericardial effusion were evaluated immunocytochemically with monoclonal anti-XIAP (#610763, BD Biosciences, San Jose, USA) 1:250, 4 degrees C x 72 h, and developed using EnVision-Plus reagents (Dako) and diaminobenzidine as chromagen.
  • The prevalence of staining for specific malignancies varied with the tissue of origin as follows: ovarian (13/13, 100%); lung (9/11, 82%), breast (6/13, 46%); gastric (4/7, 57%), colon (0/4, 0%), pancreas (2/3, 67%), gallbladder (1/1, 100%), fallopian tube (1/3, 33%), endometrial (6/7, 86%), mesothelioma (4/5, 80%), carcinoma of unknown primary (5/5, 100%) and hematopoietic malignancies (3/9, 33%).
  • Benign effusions (n = 35) were virtually XIAP-negative except for two cases (6%) in which histiocytes showed moderate staining.
  • XIAP immunostaining, when strong, allows for ready distinction of malignant from benign and reactive cell populations.
  • The degree of XIAP staining of tumor cells may be a means of identifying the most therapy-resistant cases (ie, those with strong XIAP expression), and allow additional triaging to XIAP-blocking drugs presently being developed and clinically tested.
  • [MeSH-major] Ascitic Fluid / chemistry. Biomarkers, Tumor / analysis. Immunoenzyme Techniques / methods. Peritoneal Lavage. Pleural Effusion, Malignant / chemistry. X-Linked Inhibitor of Apoptosis Protein / analysis

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 16118627.001).
  • [ISSN] 0893-3952
  • [Journal-full-title] Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
  • [ISO-abbreviation] Mod. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / X-Linked Inhibitor of Apoptosis Protein
  •  go-up   go-down


65. Creaney J, Yeoman D, Naumoff LK, Hof M, Segal A, Musk AW, De Klerk N, Horick N, Skates SJ, Robinson BW: Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma. Thorax; 2007 Jul;62(7):569-76
PDF icon [Fulltext service] Download fulltext PDF of this article and others, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Soluble mesothelin in effusions: a useful tool for the diagnosis of malignant mesothelioma.
  • BACKGROUND: The diagnosis of malignant mesothelioma is frequently difficult, the most common differential diagnosis being reactive pleural conditions and metastatic adenocarcinoma.
  • Soluble mesothelin levels in serum have recently been shown to be highly specific and moderately sensitive for mesothelioma.
  • As most patients with mesothelioma present with exudative effusions of either the pleura or the peritoneum, a study was undertaken to determine if levels of mesothelin were raised in these fluids and if the increased levels could help to distinguish mesothelioma from other causes of exudative effusion.
  • METHODS: Pleural fluid was collected from 192 patients who presented to respiratory clinics (52 with malignant mesothelioma, 56 with non-mesotheliomatous malignancies and 84 with effusions of non-neoplastic origin).
  • Peritoneal fluid was collected from 42 patients (7 with mesothelioma, 14 with non-mesotheliomatous malignancies and 21 with benign effusions).
  • RESULTS: Significantly higher levels of mesothelin were found in effusions of patients with mesothelioma; with a specificity of 98%, the assay had a sensitivity of 67% comparing patients with mesothelioma and those with effusions of non-neoplastic origin.
  • In 7 out of 10 cases mesothelin levels were raised in the effusion collected 3 weeks to 10 months before the diagnosis of mesothelioma was made; in 4 out of 8 of these, mesothelin levels were increased in the effusion but not in the serum.
  • CONCLUSIONS: Measurement of mesothelin concentrations in the pleural and/or peritoneal effusion of patients may aid in the differential diagnosis of mesothelioma in patients presenting with effusions.
  • [MeSH-major] Membrane Glycoproteins / metabolism. Mesothelioma / diagnosis. Pleura / chemistry

  • Genetic Alliance. consumer health - Mesothelioma, malignant.
  • MedlinePlus Health Information. consumer health - Mesothelioma.
  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] Br J Cancer. 1999 Nov;81(6):1059-65 [10576665.001]
  • [Cites] Cytopathology. 2000 Jun;11(3):139-51 [10877273.001]
  • [Cites] J Thorac Oncol. 2006 Feb;1(2):172-4 [17409849.001]
  • [Cites] Clin Biochem. 2000 Jul;33(5):405-10 [11018693.001]
  • [Cites] Lung Cancer. 2001 Jan;31(1):9-16 [11162861.001]
  • [Cites] Chest. 2001 Apr;119(4):1138-42 [11296181.001]
  • [Cites] Mod Pathol. 2003 Mar;16(3):192-7 [12640097.001]
  • [Cites] Lung Cancer. 2003 Jun;40(3):289-94 [12781427.001]
  • [Cites] Am J Surg Pathol. 2003 Aug;27(8):1031-51 [12883236.001]
  • [Cites] Am J Surg Pathol. 2003 Nov;27(11):1418-28 [14576474.001]
  • [Cites] Lancet. 2003 Nov 15;362(9396):1612-6 [14630441.001]
  • [Cites] Ann Intern Med. 1972 Oct;77(4):507-13 [4642731.001]
  • [Cites] Int J Cancer. 1992 Feb 1;50(3):373-81 [1735605.001]
  • [Cites] Lung. 1994;172(3):183-4 [8201832.001]
  • [Cites] Nephron. 1999;81(4):373-80 [10357643.001]
  • [Cites] Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11531-6 [10500211.001]
  • [Cites] Chest. 2004 Dec;126(6):1721-2 [15596661.001]
  • [Cites] Chest. 2004 Dec;126(6):1757-63 [15596670.001]
  • [Cites] Oncol Rep. 2005 Aug;14(2):357-62 [16012715.001]
  • [Cites] Lancet. 2005 Jul 30-Aug 5;366(9483):397-408 [16054941.001]
  • [Cites] Oncologist. 2005 Aug;10(7):501-7 [16079317.001]
  • [Cites] N Engl J Med. 2005 Oct 13;353(15):1564-73 [16221779.001]
  • [Cites] N Engl J Med. 2005 Oct 13;353(15):1591-603 [16221782.001]
  • [Cites] Am J Respir Crit Care Med. 2006 May 15;173(10):1155-60 [16456138.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):1014-20 [16702385.001]
  • [Cites] Cancer Epidemiol Biomarkers Prev. 2006 Sep;15(9):1751 [16985043.001]
  • [CommentIn] Thorax. 2007 Jul;62(7):561-2 [17600291.001]
  • [CommentIn] Thorax. 2008 Jan;63(1):87-8; author reply 87 [18156575.001]
  • (PMID = 17356060.001).
  • [ISSN] 0040-6376
  • [Journal-full-title] Thorax
  • [ISO-abbreviation] Thorax
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / GPI-Linked Proteins; 0 / Membrane Glycoproteins; 0 / mesothelin
  • [Other-IDs] NLM/ PMC2117248
  •  go-up   go-down


66. Terry NE, Fowler CL: Benign cystic mesothelioma in a child. J Pediatr Surg; 2009 May;44(5):e9-11
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cystic mesothelioma in a child.
  • Grossly, it resembled lymphangioma; however, histopathologic diagnosis was benign cystic mesothelioma (BCM), an entity that presents mainly in women of childbearing age.
  • He also underwent resection of a congenital cystic adenomatoid malformation of the right lung.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Ascites / etiology. Cystic Adenomatoid Malformation of Lung, Congenital / complications. Cystic Adenomatoid Malformation of Lung, Congenital / surgery. Diagnosis, Differential. Dyspnea / etiology. Humans. Infant. Lymphangioma / diagnosis. Male. Neoplasm Recurrence, Local / surgery. Pleural Effusion / etiology

  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 19433159.001).
  • [ISSN] 1531-5037
  • [Journal-full-title] Journal of pediatric surgery
  • [ISO-abbreviation] J. Pediatr. Surg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  •  go-up   go-down


67. Coskun A, Guven MA, Ozdemir O, Cirakli H, Karakus S: Benign cystic mesothelioma presenting as a huge pelvic mass--a case report. Eur J Gynaecol Oncol; 2006;27(6):621-2
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign cystic mesothelioma presenting as a huge pelvic mass--a case report.
  • Benign cystic mesothelioma is an extremely rare peritoneal tumor.
  • It is reported in women of childbearing [corrected] age but also in males and needs a careful [corrected] differential diagnosis between benign and malign neoplasia to choose the most [corrected] adeguate therapy.
  • [MeSH-major] Mesothelioma, Cystic / diagnosis. Ovarian Neoplasms / diagnosis. Peritoneal Neoplasms / diagnosis
  • [MeSH-minor] Abdominal Pain / etiology. Adult. Diagnosis, Differential. Female. Humans. Laparotomy

  • MedlinePlus Health Information. consumer health - Ovarian Cancer.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [ErratumIn] Eur J Gynaecol Oncol. 2007;28(1):3
  • (PMID = 17290598.001).
  • [ISSN] 0392-2936
  • [Journal-full-title] European journal of gynaecological oncology
  • [ISO-abbreviation] Eur. J. Gynaecol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
  •  go-up   go-down


68. Tischoff I, Tannapfel A: [Pathologic and anatomic evidence of peritoneal metastases]. Chirurg; 2007 Dec;78(12):1085-6, 1088-90
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [Pathologic and anatomic evidence of peritoneal metastases].
  • Peritoneal metastases are secondary tumours of the peritoneum and the most common tumours at this location.
  • Ovarian carcinoma, colorectal cancer, and gastric cancer are the most frequent ones that show peritoneal involvement, along with carcinomas of the pancreas, gallbladder, uterus, and lung.
  • Primary tumours originating in the peritoneum such as malignant peritoneal mesothelioma, primary peritoneal carcinoma, and benign peritoneal tumours along with inflammatory and reactive lesions must be differentiated from peritoneal metastases.
  • Especially in cancer of unknown primary tumour, the discrimination between primary peritoneal tumours and peritoneal metastases is difficult and often requires immunohistochemical identification.
  • [MeSH-major] Peritoneal Neoplasms / secondary
  • [MeSH-minor] Adenocarcinoma / pathology. Adenocarcinoma / secondary. Adenocarcinoma / surgery. Adolescent. Adult. Aged. Carcinoma / pathology. Carcinoma / secondary. Carcinoma / surgery. Carcinoma, Small Cell / pathology. Carcinoma, Small Cell / secondary. Carcinoma, Small Cell / surgery. Carcinoma, Squamous Cell / pathology. Carcinoma, Squamous Cell / secondary. Carcinoma, Squamous Cell / surgery. Cystadenocarcinoma, Mucinous / pathology. Cystadenocarcinoma, Mucinous / secondary. Cystadenocarcinoma, Mucinous / surgery. Diagnosis, Differential. Female. Humans. Male. Mesothelioma / pathology. Mesothelioma / surgery. Middle Aged. Neoplasms, Unknown Primary / pathology. Neoplasms, Unknown Primary / surgery. Ovarian Neoplasms / pathology. Ovarian Neoplasms / surgery. Peritonitis / pathology. Pseudomyxoma Peritonei / pathology. Pseudomyxoma Peritonei / surgery

  • COS Scholar Universe. author profiles.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18030433.001).
  • [ISSN] 0009-4722
  • [Journal-full-title] Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen
  • [ISO-abbreviation] Chirurg
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
  •  go-up   go-down


69. Cuartas JE, Maheshwari AV, Qadir R, Cooper AJ, Robinson PG, Pitcher JD Jr: Benign multicystic peritoneal mesothelioma in a cesarean-section scar presenting as a fungating mass. Int J Clin Oncol; 2008 Jun;13(3):275-8
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Benign multicystic peritoneal mesothelioma in a cesarean-section scar presenting as a fungating mass.
  • We report a case of a benign multicystic mesothelioma, which presented as a fungating mass through the anterior abdominal wall and arose in a cesarean-section scar without direct peritoneal involvement.
  • A wide local excision was done and the diagnosis was confirmed by histopathology and immunohistochemistry.
  • Although a history of previous abdominal surgery has been reported in a patient with benign multicystic mesothelioma, to the best of our knowledge, there is no report of a benign multicystic mesothelioma arising in a cesarean-section scar or presentation as a fungating skin mass.
  • A pertinent review of the literature on benign multicystic mesothelioma is also presented.
  • [MeSH-major] Cesarean Section / adverse effects. Cicatrix / pathology. Mesothelioma, Cystic / pathology. Peritoneal Neoplasms / pathology

  • Genetic Alliance. consumer health - Benign multicystic peritoneal mesothelioma.
  • MedlinePlus Health Information. consumer health - Cesarean Section.
  • MedlinePlus Health Information. consumer health - Scars.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • [Cites] BJU Int. 1999 Sep;84(4):533-4 [10468779.001]
  • [Cites] Tumori. 2003 Jan-Feb;89(1):31-5 [12729358.001]
  • [Cites] J Korean Med Sci. 1999 Apr;14(2):217-9 [10331572.001]
  • [Cites] Surg Today. 2000;30(1):98-100 [10648095.001]
  • [Cites] Int J Gynaecol Obstet. 2006 Jun;93(3):267-8 [16687143.001]
  • [Cites] Histopathology. 1996 Oct;29(4):375-7 [8910046.001]
  • [Cites] Acta Cytol. 2003 May-Jun;47(3):517-8 [12789944.001]
  • [Cites] Am J Clin Pathol. 2000 May;113(5):619-22 [10800393.001]
  • [Cites] Cleve Clin Q. 1986 Spring;53(1):109-14 [3708838.001]
  • [Cites] Histopathology. 1995 Nov;27(5):479-81 [8575742.001]
  • [Cites] Am J Surg Pathol. 1988 Oct;12(10):737-46 [3421410.001]
  • [Cites] S Afr Med J. 1981 Jan 17;59(3):85-6 [7466509.001]
  • [Cites] Radiology. 1989 Feb;170(2):333-7 [2643136.001]
  • [Cites] Cancer. 1980 May 1;45(9):2395-9 [7379036.001]
  • [Cites] Cancer. 1982 Oct 15;50(8):1615-22 [7116294.001]
  • [Cites] J Surg Oncol. 2002 Apr;79(4):243-51 [11920782.001]
  • [Cites] Cancer. 1989 Sep 15;64(6):1336-46 [2766227.001]
  • [Cites] Histopathology. 1999 May;34(5):472-4 [10231425.001]
  • [Cites] J Clin Gastroenterol. 1997 Jun;24(4):276-9 [9252860.001]
  • [Cites] World J Gastroenterol. 2006 Sep 21;12(35):5739-42 [17007034.001]
  • [Cites] Cancer. 1979 Aug;44(2):692-8 [476578.001]
  • [Cites] Int J Gynecol Cancer. 2005 Nov-Dec;15(6):1101-7 [16343188.001]
  • [Cites] Am J Surg Pathol. 1990 Apr;14 (4):375-8 [2181883.001]
  • [Cites] Obstet Gynecol Surv. 1989 Feb;44(2):89-95 [2915855.001]
  • [Cites] Hum Pathol. 2003 Apr;34(4):369-74 [12733118.001]
  • [Cites] World J Surg. 2006 Apr;30(4):560-6 [16547615.001]
  • [Cites] Eur J Gastroenterol Hepatol. 2002 Jan;14(1):77-80 [11782579.001]
  • [Cites] Pediatr Pathol. 1985;4(3-4):291-302 [3915088.001]
  • (PMID = 18553241.001).
  • [ISSN] 1341-9625
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  •  go-up   go-down


70. Que Y, Wang X, Liu Y, Li P, Ou G, Zhao W: Ultrasound-guided biopsy of greater omentum: an effective method to trace the origin of unclear ascites. Eur J Radiol; 2009 May;70(2):331-5
PDF icon [Fulltext service] Get downloadable fulltext PDFs of articles closely matching to this article, as many as you want.

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The purpose of our study was to assess the utility of greater omentum biopsy under the guidance of ultrasound (US) in tracing the origin of unclear ascites and differentiating benign and malignant ascites.
  • The sonograms of greater omentum were evaluated before undergoing the ultrasound-guided biopsy and a biopsy was considered successful if a specific benign or malignant diagnosis was rendered by the pathologist.
  • RESULTS: Successful biopsy was rendered for 182 biopsy procedures (93.8%, 182/194) including tuberculosis (n=114), chronic inflammation (n=3), metastases (n=58), malignant mesothelioma (n=6) and pseudomyxoma peritonei (n=1).
  • According to the results of biopsy and follow-up, the sensitivity and specificity of biopsy in distinguishing malignant ascites from benign ascities were respectively 95.6% (65/68) and 92.9% (117/126).
  • No "cerebral fissure" sign was observed in peritoneal carcinomatosis.
  • Moreover, if the specific "cerebral fissure" sign was combined with the biopsy results, the specificity of biopsy in distinguishing malignant ascites from benign ascits increased to 96.8% (122/126).
  • "Cerebral fissure" sign of greater omentum was a specific sign in indicating the tuberculous peritonitis and could increase the specificity of biopsy in distinguishing malignant ascites from benign ascits if combined with the biopsy results.
  • [MeSH-major] Ascites / pathology. Ascites / ultrasonography. Biopsy, Needle / methods. Omentum / pathology. Omentum / ultrasonography. Peritoneal Diseases / pathology. Peritoneal Diseases / ultrasonography. Ultrasonography, Interventional / methods

  • MedlinePlus Health Information. consumer health - Peritoneal Disorders.
  • [Email] Email this result item
    Email the results to the following email address:   [X] Close
  • (PMID = 18328658.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  •  go-up   go-down






Advertisement