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Items 1 to 34 of about 34
1. Tam ES, Chen EC, Nijhawan N, Harvey JT, Howarth D, Oestreicher JH: Solitary fibrous tumor of the orbit: a case series. Orbit; 2008;27(6):426-31
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Solitary fibrous tumor of the orbit: a case series.
  • PURPOSE: Solitary fibrous tumor (SFT) occurs rarely in the orbit.
  • We present four such cases, representing one of the largest case series reported to date of this rare orbital tumor.
  • All four patients underwent CT scan to confirm the diagnosis of an orbital mass, which was then excised.
  • One of these cases demonstrated residual tumor on follow-up CT scan, which remained unchanged at one-year follow-up.
  • No evidence of residual tumor was found in the other three cases, despite one having malignant pathology.
  • CONCLUSION: SFT is a rare and generally benign tumor of the orbit.
  • Immunohistochemical testing with CD34 is necessary to confirm the diagnosis.
  • Although en bloc tumor resection is the definitive treatment, residual tumor may remain stable for some time.
  • [MeSH-major] Fibroma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Female. Humans. Male. Middle Aged. Neoplasm Proteins / analysis. Tomography, X-Ray Computed. Vimentin / analysis

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  • (PMID = 19085297.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins; 0 / Vimentin
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2. Bignami M, Dallan I, Battaglia P, Lenzi R, Pistochini A, Castelnuovo P: Endoscopic, endonasal management of sinonasal haemangiopericytoma: 12-year experience. J Laryngol Otol; 2010 Nov;124(11):1178-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • All patients underwent endoscopic, endonasal resection of their tumour.
  • Local recurrence was diagnosed in only one patient (10 per cent), who subsequently underwent a combined resection (endoscopic and external) with orbital exenteration.
  • CONCLUSIONS: Sinonasal haemangiopericytomas are rare tumours that are usually benign.
  • [MeSH-major] Endoscopy / methods. Hemangiopericytoma / surgery. Neoplasm Recurrence, Local / surgery. Nose Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery
  • [MeSH-minor] Adult. Aged. Female. Humans. Length of Stay. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Staging. Reoperation. Retrospective Studies. Treatment Outcome

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  • (PMID = 20438660.001).
  • [ISSN] 1748-5460
  • [Journal-full-title] The Journal of laryngology and otology
  • [ISO-abbreviation] J Laryngol Otol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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3. Merani R, Khannah G, Mann S, Ghabrial R: Orbital leiomyoma: a case report with clinical, radiological and pathological correlation. Clin Exp Ophthalmol; 2005 Aug;33(4):408-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital leiomyoma: a case report with clinical, radiological and pathological correlation.
  • Orbital leiomyoma is a benign tumour of smooth muscle origin that can be clinically, radiologically and histopathologically difficult to diagnose due to the rarity of leiomyomas in this location.
  • Microscopically the lesion was a well-circumscribed tumour composed of spindle cells.
  • There were no light microscopic features to suggest malignancy, and immunohistochemistry was used to confirm the diagnosis of leiomyoma.
  • Leiomyoma is a tumour that is rarely found in the orbit most likely due to the paucity of smooth muscle in this location.
  • The differential diagnosis is wide, and the role of radiology, histology and immunohistochemistry in the diagnosis of leiomyoma is discussed.
  • Surgical excision in this case excluded malignancy, provided a definitive diagnosis of a rare entity and resulted in marked clinical improvement.
  • [MeSH-major] Leiomyoma / pathology. Leiomyoma / radiography. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography
  • [MeSH-minor] Actins / analysis. Aged. Antigens, CD34 / analysis. Biomarkers, Tumor / analysis. Desmin / analysis. Diagnosis, Differential. Female. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Ophthalmologic Surgical Procedures. Tomography, X-Ray Computed

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  • (PMID = 16033356.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Actins; 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / Desmin
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4. Hajda M, Korányi K, Salomváry B, Bajcsay A: [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours]. Magy Onkol; 2005;49(1):65-70
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  • [Title] [Clinical presentation, differential diagnosis and treatment of lacrimal gland tumours].
  • Epithelial lacrimal gland tumours, which may be benign or malignant (benign pleomorphic adenoma, malignant pleomorphic adenocarcinoma, adenoid cystic carcinoma, other carcinomas).
  • 4. Other tumours (dermoid cyst, haemangioma, neurinoma, haemangiopericytoma, metastatic tumour).
  • Of the 59 primary epithelial tumours 62.7% was benign and 37.3% was malignant.
  • The differential diagnosis and management are based on the clinical presentations, imaging studies and histological examination.
  • The prognosis of pleomorphic adenomas depends on the early diagnosis and radical surgical excision of the lesion.
  • [MeSH-major] Eye Neoplasms / diagnosis. Eye Neoplasms / therapy. Lacrimal Apparatus. Orbital Diseases / diagnosis. Orbital Diseases / therapy
  • [MeSH-minor] Adenocarcinoma / diagnosis. Adenocarcinoma / therapy. Adenoma / diagnosis. Adenoma / therapy. Cystadenocarcinoma / diagnosis. Cystadenocarcinoma / therapy. Diagnosis, Differential. Granuloma / diagnosis. Granuloma / therapy. Hodgkin Disease / diagnosis. Hodgkin Disease / therapy. Humans. Leukemia / diagnosis. Leukemia / therapy. Lymphoma / diagnosis. Lymphoma / therapy. Lymphoma, Non-Hodgkin / diagnosis. Lymphoma, Non-Hodgkin / therapy. Orbital Pseudotumor / diagnosis. Orbital Pseudotumor / therapy. Plasmacytoma / diagnosis. Plasmacytoma / therapy. Prognosis. Retrospective Studies. Sarcoidosis / diagnosis. Sarcoidosis / therapy. Treatment Outcome

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  • (PMID = 15902337.001).
  • [ISSN] 0025-0244
  • [Journal-full-title] Magyar onkologia
  • [ISO-abbreviation] Magy Onkol
  • [Language] hun
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Hungary
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5. Saetti R, Silvestrini M, Narne S: Ethmoid osteoma with frontal and orbital extension: endoscopic removal and reconstruction. Acta Otolaryngol; 2005 Oct;125(10):1122-5
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  • [Title] Ethmoid osteoma with frontal and orbital extension: endoscopic removal and reconstruction.
  • Endoscopy provides a safe and effective way of treating craniofacial bony benign lesions.
  • This approach permits not only complete removal of the tumour, but also reconstruction of the bony boundaries as necessary.
  • Osteoma is a rare, osteogenic tumour that usually grows slowly and asymptomatically.
  • It is the most frequent benign neoplasm of the nose and paranasal sinuses.
  • Orbital extension is a rare event that can give rise to ocular signs and symptoms; in such a case treatment is mandatory, although debate persists regarding the optimal approach.
  • We report the case of a bulky fronto-ethmo-orbital osteoma that was treated using an endoscopic trans-nasal approach.
  • The medial wall of the orbit was repaired by means of an implant of porous polyethylene endoscopically positioned using an "underlay" technique.
  • A CT scan performed 6 months postoperatively showed good ventilation of the sinonasal cavity and effective reconstruction of the medial orbital wall.
  • [MeSH-minor] Adult. Endoscopy. Female. Frontal Bone / pathology. Frontal Bone / surgery. Humans. Neoplasm Invasiveness. Orbit / pathology. Orbit / surgery. Reconstructive Surgical Procedures

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  • (PMID = 16298798.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Norway
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6. Burduk PK, Seredyka-Burduk M, Olejarz E: [Giant tumor of the orbit--a case of hidradenoma]. Otolaryngol Pol; 2007;61(6):1017-20
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  • [Title] [Giant tumor of the orbit--a case of hidradenoma].
  • Orbital tumors are very differential group of lesions.
  • More often a benign lesions is found than malignant.
  • We present a case of 62 years old man with large expansion of benign tumor of the orbit with exophthalmus, eye movement disability and complete blindness.
  • The authors performed radical surgery with removing of the orbit content.
  • Histopathology described a very rare tumor of the orbit-hidradenoma.
  • [MeSH-major] Adenoma, Sweat Gland / diagnosis. Orbital Neoplasms / diagnosis. Sweat Gland Neoplasms / diagnosis

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  • (PMID = 18546956.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Poland
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7. Wiegand S, Zimmermann AP, Eivazi B, Sesterhenn AM, Sekundo W, Bien S, Werner JA, Barth PJ: Analysis of clinically suspected orbital cavernomas. Br J Ophthalmol; 2010 Dec;94(12):1653-6
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  • [Title] Analysis of clinically suspected orbital cavernomas.
  • BACKGROUND: Orbital cavernomas are low-flow vascular malformations that are the most common benign neoplasms of the orbit in adults, typically becoming symptomatic in the middle age.
  • METHODS: The medical records of six patients with clinically suspected orbital cavernomas receiving elective surgical excision were analysed concerning symptoms, physical findings, treatment results and visual outcome.
  • The pathologic slides were evaluated, and additional immunohistochemical stains were done if necessary to obtain diagnosis.
  • RESULTS: Histologic evaluation revealed three of six cases not being cavernomas, although the clinical and macroscopic findings were consistent with orbital cavernomas.
  • Two of them were haemorrhagic lymphangiomas, and one was a solitary fibrous tumour.
  • CONCLUSIONS: Haemorrhagic lymphangiomas and other vascular tumours may mimic orbital cavernomas regarding anamnesis, radiologic and intraoperative findings and gross examination.
  • Therefore, exact histologic evaluation is necessary to get the correct diagnosis.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Lymphangioma / diagnosis. Orbital Neoplasms / diagnosis. Vascular Malformations / diagnosis
  • [MeSH-minor] Adolescent. Adult. Child. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Regional Blood Flow. Treatment Outcome. Young Adult

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  • (PMID = 20494913.001).
  • [ISSN] 1468-2079
  • [Journal-full-title] The British journal of ophthalmology
  • [ISO-abbreviation] Br J Ophthalmol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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8. deSousa JL, Meligonis G, Malhotra R: Giant cell angiofibroma of the orbit with periosteal adherence. Clin Exp Ophthalmol; 2006 Dec;34(9):886-8
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  • [Title] Giant cell angiofibroma of the orbit with periosteal adherence.
  • We report a case of orbital giant cell angiofibroma, an unusual, recently reported benign spindle cell neoplasm.
  • Preoperative clinical assessment and radiology suggested a benign mass and early operative findings were in concordance with this.
  • As with some lymphangiomas, this is another benign orbital tumour which may present difficulties in complete surgical excision that are not anticipated based on the preoperative findings.
  • [MeSH-major] Angiofibroma / diagnosis. Giant Cell Tumors / diagnosis. Orbital Neoplasms / diagnosis. Periosteum / pathology
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Ophthalmologic Surgical Procedures. Tissue Adhesions. Tomography, X-Ray Computed

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  • (PMID = 17181622.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
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9. Jacopo G, Micaela I, Italo C, Luigi C, Larocca LM, Gaetano P: Atypical sinonasal Schwannomas: a difficult diagnostic challenge. Auris Nasus Larynx; 2009 Aug;36(4):482-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVE: Schwannomas are benign tumours arising from Schwann cells of the peripheral nerve sheath.
  • In the second case, due to initial visual symptoms and to the ethmoid-orbital compartment involvement, we performed a sinonasal endoscopy and collected a biopsy which resulted to be fundamental in the diagnostic assessment.
  • Tumour excision was then obtained throughout an intracranial/endonasal approach.
  • In the first case, diagnosis was made only post-operatively after histological examination.
  • CONCLUSIONS: Nasal endoscopy was extremely important in making the diagnosis, allowing an accurate assessment of the tumour extension and a biopsy.
  • The diagnosis of sinonasal Schwannomas remains challenging; sometimes, clinical behaviour and modern imaging may be misleading.
  • [MeSH-major] Endoscopy. Magnetic Resonance Angiography. Neurilemmoma / diagnosis. Nose Neoplasms / diagnosis. Orbital Neoplasms / diagnosis. Paranasal Sinus Neoplasms / diagnosis
  • [MeSH-minor] Biopsy. Contrast Media. Cysts / diagnosis. Diagnosis, Differential. Humans. Immunohistochemistry. Magnetic Resonance Spectroscopy. Male. Middle Aged. Young Adult

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  • (PMID = 19261409.001).
  • [ISSN] 1879-1476
  • [Journal-full-title] Auris, nasus, larynx
  • [ISO-abbreviation] Auris Nasus Larynx
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Netherlands
  • [Chemical-registry-number] 0 / Contrast Media
  • [Number-of-references] 20
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10. Ahmad Z, Khurshid A, Qureshi A: Primary orbital yolk sac tumour in a 14-year-old girl. BMJ Case Rep; 2009;2009
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  • [Title] Primary orbital yolk sac tumour in a 14-year-old girl.
  • Yolk sac tumour is a common malignant germ cell tumour, which usually occurs in the testes or ovaries of infants.
  • Extragonadal germ cell tumours of the head and neck region account for 5% of all benign and malignant germ cell tumours.
  • The orbit is an extremely unusual location for development of primary yolk sac tumour.
  • The present report concerns the case of a yolk sac tumour in a 14-year-old girl, arising as a primary tumour of the orbit with invasion of periorbital and intracranial spaces.

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  • (PMID = 22096462.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3027343
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11. Arora R, Monga S, Mehta DK, Raina UK, Gogi A, Gupta SD: Malignant fibrous histiocytoma of the conjunctiva. Clin Exp Ophthalmol; 2006 Apr;34(3):275-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • They can occur in any part of the body including the orbital tissues.
  • Eleven of these were classified as benign, and the rest were malignant fibrous histiocytomas.
  • Benign fibrous histiocytomas have been reported in the orbit, eyelid, episclera and conjunctiva.
  • Malignant fibrous histiocytoma has been well described in the orbit, but rarely as a primary conjunctival tumour.
  • The rarity of the tumour makes its diagnosis and management a challenge.
  • Herein, the clinicopathological features of a case of malignant fibrous histiocytoma are presented and its management with wide excision and cryotherapy followed by ocular reconstruction with amniotic membrane transplant is discussed.
  • [MeSH-minor] Biomarkers, Tumor / metabolism. Humans. Male. Middle Aged. Neoplasm Proteins / metabolism

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  • (PMID = 16671910.001).
  • [ISSN] 1442-6404
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Australia
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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12. Kinnunen I, Aitasalo K: A review of 59 consecutive patients with lesions of the anterior cranial base operated on using the subcranial approach. J Craniomaxillofac Surg; 2006 Oct;34(7):405-11
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PATIENTS: Fifty-nine consecutive patients underwent surgery using the subcranial approach for treating various benign and malignant neoplasms, for repair of frontobasal-midfacial fractures, and for repair of cerebrospinal fluid leaks.
  • RESULTS: Nineteen of the patients were operated on because of combined fronto-naso-orbital and skull base fractures, 37 were tumour cases, and 3 patients required surgical repair for cerebrospinal fluid leakage.
  • CONCLUSION: The subcranial approach affords exposure to the orbital, sphenoethmoidal, and clivus regions, as well as to the nasal and paranasal cavities.
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Cranial Fossa, Anterior / surgery. Female. Frontal Bone / injuries. Humans. Infant. Male. Meningitis / etiology. Middle Aged. Nasal Bone / injuries. Olfaction Disorders / etiology. Olfactory Nerve Injuries. Orbital Fractures / surgery. Postoperative Complications. Retrospective Studies. Skull Base Neoplasms / surgery. Skull Fractures / surgery. Subdural Effusion / surgery. Treatment Outcome

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  • (PMID = 16965917.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Scotland
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13. Stieve M, Schwab B, Haupt C, Bisdas S, Heermann R, Lenarz T: Intraoperative computed tomography in otorhinolaryngology. Acta Otolaryngol; 2006 Jan;126(1):82-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • CONCLUSIONS: Intraoperative CT surgery provides the surgeon with additional information about the altered surgical site in difficult anatomical situations.
  • In soft-tissue surgery it is advisable to apply a contrast agent in order to achieve good soft-tissue contrast, thus allowing the tumour to be adequately distinguished from benign tissue.
  • Saving information and transferring it to the intraoperative site may, however, be problematic.
  • MATERIAL AND METHODS: Intraoperative CT was applied using the Tomoscan M in 46 cases in order to demonstrate the surgical benefit of the following procedures: endonasal surgical procedures on the paranasal sinuses (maxillary and ethmoidal sinusitis, anterior fracture of the sphenoidal sinus); tumour removal by means of laser surgery (carcinomas of the hypopharynx and larynx); and cochlear implantation (to verify the electrode position).
  • Intraoperative imaging proved particularly helpful in revision surgery for chronic sinusitis in cases with missing anatomical landmarks owing to previous surgeries, where there is an increased risk of inflicting damage to the skull base or orbita.
  • In soft-tissue procedures, such as tumour removal by means of laser surgery, it proved possible to visualize the resection borders of malignant tumours.
  • [MeSH-minor] Cochlear Implantation / instrumentation. Cochlear Implantation / methods. Equipment Design. Humans. Image Processing, Computer-Assisted. Orbital Fractures / radiography. Orbital Fractures / surgery. Paranasal Sinuses / radiography. Paranasal Sinuses / surgery. Soft Tissue Neoplasms / radiography. Soft Tissue Neoplasms / surgery

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  • (PMID = 16308259.001).
  • [ISSN] 0001-6489
  • [Journal-full-title] Acta oto-laryngologica
  • [ISO-abbreviation] Acta Otolaryngol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Norway
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14. Farmer JP, Lamba M, McDonald H, Commons AS: Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis. Can J Ophthalmol; 2006 Apr;41(2):216-20
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital giant cell angiofibroma: immuno-histochemistry and differential diagnosis.
  • On radiologic examination, the mass was seen to extend into the anterior orbit.
  • COMMENTS: Giant cell angiofibroma is a benign spindle cell neoplasm characterized by multinucleated giant cells and pseudovascular spaces with a propensity to occur in the anterior soft tissues of the orbit of middle-aged adults.
  • It is part of a wide differential diagnosis of tumours that can be separated by various histologic and immunohistochemical features, which are discussed in the report.
  • It is important to consider it preoperatively because the vascular nature of this tumour may create problems with hemostasis during excision.

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  • (PMID = 16767212.001).
  • [ISSN] 0008-4182
  • [Journal-full-title] Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
  • [ISO-abbreviation] Can. J. Ophthalmol.
  • [Language] ENG
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Neoplasm Proteins
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15. Kohlhof JK, Müller-Richter U, Driemel O, Sachs H: [Pleomorphic malignant fibrous histiocytoma of the periorbital region]. Klin Monbl Augenheilkd; 2007 Mar;224(3):203-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Transliterated title] Pleomorphes malignes fibröses Histiozytom der Periorbitalregion.
  • PATIENT: A 91 year old female patient presented because of a prominent tumour in the upper right periorbital region.
  • As stated in the case history, the tumour had developed within the previous 6 months.
  • The tumour measured about 3 x 4 cm.
  • Due to the mass of the tumour a ptosis was present.
  • CLINIC: Neither CT nor MRI could give a clue to the tumour entity.
  • A biopsy was classified as a malignant fibrous tumour with the subclassification of an atypical fibroxanthoma.
  • The final histopathological classification after total excision of the tumour showed perineural growth and angioinvasion.
  • Therefore the tumour classification was changed to pleomorphic malignant fibrous histiocytoma (undifferentiated pleomorphic sarcoma).
  • CONCLUSION: The histopathological examination could not provide the correct diagnosis initially.
  • Immunohistochemical stainings (Vimentin) were carried out to characterise the tumour.
  • In the process of finding the right diagnosis sometimes a change from benign to malignant occurs and alters the treatment regime.
  • [MeSH-major] Histiocytoma, Malignant Fibrous / pathology. Histiocytoma, Malignant Fibrous / radiography. Orbital Neoplasms / pathology. Orbital Neoplasms / radiography


16. Chanfi M: [Tuberous angioma in an infant: a case study]. J Fr Ophtalmol; 2005 Sep;28(7):774
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  • Tuberous angioma of the orbit is the most frequent benign tumor of the orbit in children.
  • Angiomatous tumors in general, and more particularly tuberous angioma tumors, are classed among the primary tumors of the orbit.

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  • (PMID = 16208215.001).
  • [ISSN] 1773-0597
  • [Journal-full-title] Journal français d'ophtalmologie
  • [ISO-abbreviation] J Fr Ophtalmol
  • [Language] fre
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] France
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17. Rødahl E, Lybaek H, Arnes J, Ness GO: Chromosomal imbalances in some benign orbital tumours. Acta Ophthalmol Scand; 2005 Jun;83(3):385-91
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  • [Title] Chromosomal imbalances in some benign orbital tumours.
  • PURPOSE: To examine benign orbital tumours for chromosomal imbalances.
  • METHODS: Specimens obtained from orbital tumours were screened for chromosomal imbalances using high resolution comparative genomic hybridization (CGH).
  • We did not observe common chromosomal gains or losses that were characteristic for orbital presentation of the tumours.
  • The clinical relevance of the abnormalities is uncertain, but they may indicate the position of genes that could play a role in tumour development.
  • [MeSH-major] Adenoma, Pleomorphic / genetics. Chromosome Aberrations. Hemangioma, Cavernous / genetics. Neurilemmoma / genetics. Orbital Neoplasms / genetics

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  • (PMID = 15948796.001).
  • [ISSN] 1395-3907
  • [Journal-full-title] Acta ophthalmologica Scandinavica
  • [ISO-abbreviation] Acta Ophthalmol Scand
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Denmark
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18. Rousseau A, Kujas M, van Effenterre R, Boch AL, Carpentier A, Leroy JP, Poirier J: Primary intracranial myopericytoma: report of three cases and review of the literature. Neuropathol Appl Neurobiol; 2005 Dec;31(6):641-8
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  • Myopericytoma is a benign tumour generally arising in the subcutaneous and superficial soft tissues of the extremities.
  • The tumour involved, respectively, the anterior cranial fossa, the orbital apex and the pineal region.
  • Myopericytoma is a recently described neoplasm, and it is likely that reappraisal of intracranial haemangiopericytoma with which it shares many histopathologic features will lead to more case reports of primary intracranial myopericytoma.

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  • (PMID = 16281913.001).
  • [ISSN] 0305-1846
  • [Journal-full-title] Neuropathology and applied neurobiology
  • [ISO-abbreviation] Neuropathol. Appl. Neurobiol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] England
  • [Number-of-references] 24
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19. Bekibele CO, Fasola OA, Okojie VN, Komolafe OO, Oluwasola OA, Emejulu JK, Ajaiyeoba AI, Baiyeroju AM: Visual impairment from fibrous dysplasia in a middle-aged African man: a case report. J Med Case Rep; 2009;3:14
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  • INTRODUCTION: Fibrous dysplasia is a benign tumour of the bones and is a disease of unknown aetiology.
  • This report discusses a case of proptosis and visual deterioration with associated bony mass involving the right orbit.
  • Proptosis was preceded by trauma but was non-pulsatile with no thrill or bruit but was associated with bony orbital mass.
  • Computed tomography showed an expansile bony mass involving all the walls of the orbit.
  • The bony orbital mass was diagnosed histologically as fibrous dysplasia.
  • Treatment included orbital exploration and orbital shaping to create room for the globe and relieve pressure on the optic nerve.
  • CONCLUSION: Fibrous dysplasia should be considered in the differential diagnosis of slowly developing proptosis with associated visual loss in young adults.

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  • [Cites] Am J Pathol. 1997 Dec;151(6):1587-600 [9403710.001]
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  • (PMID = 19144124.001).
  • [ISSN] 1752-1947
  • [Journal-full-title] Journal of medical case reports
  • [ISO-abbreviation] J Med Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2633003
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20. Lindegaard J, Heegaard S, Toft PB, Nysom K, Prause JU: Malignant transformation of a medulloepithelioma of the optic nerve. Orbit; 2010 Jun;29(3):161-4
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  • METHODS: A 3-year-old boy presented with right-sided proptosis, swollen eyelids, restricted ocular movements, pain and nausea.
  • A benign non-teratoid medulloepithelioma of the optic nerve was surgically removed.
  • Due to relapse in the orbit 10 months postoperatively enucleation and partial orbital exenteration were performed.
  • This is the first case described of a benign medulloepithelioma of the optic nerve, later transforming into a malignant tumour.
  • Furthermore; it should be considered as a differential diagnosis when observing a tumour of the optic nerve in a child.
  • [MeSH-major] Cell Transformation, Neoplastic / pathology. Neoplasm Recurrence, Local / pathology. Neuroectodermal Tumors, Primitive / pathology. Optic Nerve Neoplasms / pathology
  • [MeSH-minor] Biopsy, Needle. Chemotherapy, Adjuvant. Child, Preschool. Exophthalmos / diagnosis. Exophthalmos / etiology. Eye Enucleation / methods. Follow-Up Studies. Humans. Immunohistochemistry. Magnetic Resonance Imaging / methods. Male. Orbit Evisceration / methods. Radiotherapy, Adjuvant. Risk Assessment. Stem Cell Transplantation. Treatment Outcome

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  • (PMID = 20497085.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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21. Sarkar S, Singh M, Nag D, Dutta H, Banerjee A, Bhaduri G, Jha A: A case report of unifocal Langerhans' cell histiocytosis or eosinophilic granuloma. J Indian Med Assoc; 2007 Apr;105(4):218, 220
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  • A case of unifocal Langerhans' cell histiocytosis or eosinophilic granuloma in a child is reported where the frontal, zygomatic and maxillary bones of the left orbital wall are affected.
  • As eosinophilic granuloma is a rare disease and the involvement of maxillary bone in orbital eosinophilic granuloma is not well documented in the literature, this case is reported for its unusual involvement of 3 bones at a single site.
  • The diagnosis was established by clinical, radiological and histological findings.
  • As no other system or site was involved and considering the osseous involvement of multiple bones at one site, local radiotherapy was preferred as the mode of treatment.
  • The patient responded favourably to radiotherapy with reduction of proptosis and tumour mass but there was no visual recovery.
  • In the absence of universal agreement over the mode of treatment, the result emphasises the probable benign nature of the tumour and the need to withhold more aggressive treatment modalities for extensive multisystem involvements.
  • [MeSH-major] Histiocytosis, Langerhans-Cell / diagnosis. Treatment Outcome
  • [MeSH-minor] Child. Diagnosis, Differential. Eosinophilic Granuloma / diagnosis. Eosinophilic Granuloma / pathology. Eosinophilic Granuloma / radiotherapy. Exophthalmos / radiotherapy. Humans. Male. Osteolysis

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  • (PMID = 17822194.001).
  • [ISSN] 0019-5847
  • [Journal-full-title] Journal of the Indian Medical Association
  • [ISO-abbreviation] J Indian Med Assoc
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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22. Nagulić M, Nikolić I, Manojlović-Gacić E, Skender-Gazibara M: Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period. Vojnosanit Pregl; 2010 Jun;67(6):507-10
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  • [Title] Multiple cavernous hemangiomas of the orbit: separate occurrence within a 24-year period.
  • BACKGROUND: Cavernous hemangioma is a frequent and the most common, primary, benign tumor of the orbit in adults.
  • Multiple orbital cavernous hemangiomas without signs of hemangiomatosis are rare.
  • Tumor recurrence is supposed to develop from vasculature that is present already in response to a proliferate stimulus.
  • CASE REPORT: A 39-year-old female with painless proptosis of the right orbit was found to have four orbital tumors.
  • Six years later, another, the fifth one cavernous hemangioma was totally excised from the same orbit.
  • Nine years after the first operation, reorbitotomy was performed because of positive radiological and clinical signs of de novo tumor in the orbit.
  • CONCLUSION: This case show the possibility of cavernous hemangioma recurrence after a previously totally excised tumor, separated more than two decades.
  • A very long follow-up of the patients operated for these benign tumor lesions is recommended.
  • [MeSH-major] Hemangioma, Cavernous. Neoplasm Recurrence, Local. Neoplasms, Multiple Primary. Orbital Neoplasms

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  • (PMID = 20629431.001).
  • [ISSN] 0042-8450
  • [Journal-full-title] Vojnosanitetski pregled
  • [ISO-abbreviation] Vojnosanit Pregl
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Serbia
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23. Składzień J, Oleś K, Moskała M, Strek P, Urbanik A, Stachura J, Zagólski O: [Own experience in treatment of patients with advanced tumours of the paranasal sinuses and the orbit, penetrating to the anterior and medial cranial fossa--preliminary report]. Otolaryngol Pol; 2007;61(4):416-22
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  • [Title] [Own experience in treatment of patients with advanced tumours of the paranasal sinuses and the orbit, penetrating to the anterior and medial cranial fossa--preliminary report].
  • An en bloc excision of the tumour can be accomplished.
  • RESULTS: Lesions were malignant in 7 patients and benign in the remaining 33.
  • Craniofacial resection is the only surgical approach with acceptable rate of complications in selected patients with tumour comprising the anterior and medial cranial base, nasal cavity, paranasal sinuses, nasopharynx and orbits.
  • [MeSH-major] Cranial Fossa, Anterior / surgery. Cranial Fossa, Middle / surgery. Orbital Neoplasms / surgery. Paranasal Sinus Neoplasms / surgery. Skull Base Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Male. Middle Aged. Neoplasm Invasiveness. Neoplasm Staging. Retrospective Studies. Treatment Outcome

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  • (PMID = 18260224.001).
  • [ISSN] 0030-6657
  • [Journal-full-title] Otolaryngologia polska = The Polish otolaryngology
  • [ISO-abbreviation] Otolaryngol Pol
  • [Language] pol
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Poland
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24. Wanyura H, Kamiński A, Stopa Z: Treatment of osteomas located between the anterior cranial base and the face. J Craniomaxillofac Surg; 2005 Aug;33(4):267-75
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  • OBJECTIVE: Osteomas located on the border between the anterior cranial base and the facial region are benign, often asymptomatic and usually slow growing.
  • In all patients a radical surgical removal of the tumour was performed via bifrontal craniotomy, with an extradural approach to the anterior cranial fossa.
  • [MeSH-minor] Adult. Blepharoptosis / etiology. Diplopia / etiology. Female. Headache / etiology. Humans. Male. Middle Aged. Neoplasm Recurrence, Local / surgery. Orbital Neoplasms / surgery. Retreatment. Treatment Outcome

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  • (PMID = 15975808.001).
  • [ISSN] 1010-5182
  • [Journal-full-title] Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery
  • [ISO-abbreviation] J Craniomaxillofac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Scotland
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25. Sterker I, Frerich B: [Orbital diseases in childhood]. Klin Monbl Augenheilkd; 2006 Jan;223(1):59-67
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  • [Title] [Orbital diseases in childhood].
  • BACKGROUND: Orbital diseases in childhood are rare and differ from orbital lesions occurring in adults.
  • Most paediatric orbital tumours are benign, but rapid tumour growth can nevertheless threaten vision or lives.
  • PATIENTS: Retrospectively, we analyzed data of 41 consecutive patients with orbital disease, treated in our hospital between 2000 and 2004.
  • RESULTS: All children (from neonatals up to 16 years of age) with orbital disease were included in the study.
  • The most common benign disease of the entire collective was an epidermal cyst (n = 18), followed by orbital capillary haemangioma (n = 4) in children under 3 years, and preseptal cellulitis in children older than 3 years.
  • 5 patients were treated for malignant tumours, of which one patient under 3 years had an orbital metastasis of an abdominal neuroblastoma.
  • CONCLUSION: Awareness of orbital diseases in childhood, as a rare entity, is crucial for timely diagnosis and appropriate treatment, to save the vision and lives of affected children.
  • [MeSH-major] Orbital Diseases / diagnosis. Orbital Neoplasms / diagnosis
  • [MeSH-minor] Adolescent. Child. Child, Preschool. Cross-Sectional Studies. Diagnosis, Differential. Female. Humans. Incidence. Infant. Infant, Newborn. Male

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  • (PMID = 16418936.001).
  • [ISSN] 0023-2165
  • [Journal-full-title] Klinische Monatsblätter für Augenheilkunde
  • [ISO-abbreviation] Klin Monbl Augenheilkd
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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26. Lima NB, Jankowski R, Georgel T, Grignon B, Guillemin F, Vignaud JM: Respiratory adenomatoid hamartoma must be suspected on CT-scan enlargement of the olfactory clefts. Rhinology; 2006 Dec;44(4):264-9
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  • OBJECTIVE: To demonstrate that Respiratory Epithelial Adenomatoid Hamartoma (REAH) of the nose, a recently individualized benign tumour, is characterized by a significant widening of the CT-scan width of the olfactory clefts.
  • Total nasal width (i.e. the distance between both medial orbital walls) was not found to be different between groups in both planes.
  • Bilateral REAH represent a genuine differential diagnosis of Nasal Polyposis; the CT-scan appears as a major clue to differentiate the two diseases.
  • [MeSH-minor] Adult. Aged. Aged, 80 and over. Diagnosis, Differential. Endoscopy. Female. Humans. Male. Middle Aged. Nasal Polyps / radiography. Retrospective Studies. Statistics, Nonparametric

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  • (PMID = 17216743.001).
  • [ISSN] 0300-0729
  • [Journal-full-title] Rhinology
  • [ISO-abbreviation] Rhinology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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27. Cunniffe G, Fernández J, Alonso T, Balaguer O, Dinares C, Huguet P, Medel R: Thyroid orbitopathy obscuring the diagnosis of a rare neuromuscular hamartoma of the superior rectus muscle in an adult. Orbit; 2010 Jun;29(3):168-70
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  • [Title] Thyroid orbitopathy obscuring the diagnosis of a rare neuromuscular hamartoma of the superior rectus muscle in an adult.
  • A neuromuscular hamartoma is a rare benign tumour that is most frequently associated with peripheral nerves.
  • An initial diagnosis of thyroid orbitopathy was made and he had a limited response to two courses of oral steroid administered in another centre.
  • Orbital CT scan showed a thickening of the recti muscles and particularly the left superior rectus and overlying soft tissue.
  • The orbital fat biopsy showed no pathological findings.
  • [MeSH-major] Graves Ophthalmopathy / diagnosis. Hamartoma / diagnosis. Neuromuscular Diseases / diagnosis. Oculomotor Muscles / pathology. Orbital Diseases / diagnosis
  • [MeSH-minor] Biopsy, Needle. Diagnosis, Differential. Follow-Up Studies. Humans. Hyperthyroidism / complications. Hyperthyroidism / surgery. Immunohistochemistry. Male. Middle Aged. Monitoring, Physiologic / methods. Ophthalmologic Surgical Procedures / methods. Risk Assessment. Severity of Illness Index. Thyroidectomy / methods. Tomography, X-Ray Computed

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  • (PMID = 20497087.001).
  • [ISSN] 1744-5108
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
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28. Wilde F, Neid M, Schulz T, Sterker I, Hemprich A, Frerich B: [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases]. Mund Kiefer Gesichtschir; 2005 Nov;9(6):404-8
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  • [Title] [Hemangiopericytoma (extrapleural solitary fibrous tumour). Exemplified and discussed on the basis of two cases].
  • [Transliterated title] Hämangioperizytom (extrapleuraler solitärer fibröser Tumor). Dargestellt und diskutiert anhand zweier Patientenbeispiele.
  • It is a very uncommon potentially malignant vascular tumour which can occur at every site of the body.
  • The diagnosis of "hemangiopericytoma" is now only determined if a constant histological picture of hemangiopericytoma is present.
  • The tumour can lead to lymphogenous or hematogenous metastasis.
  • CASE REPORTS: Patient 1: 60 years, female; diagnosis: malignant suboccipital hemangiopericytoma; size: 4.9 x 4.5 x 4.2 cm; pT1bNXMX L0 V0 Pn0; stage IA; grading G1; R0.Patient 2: 38 years, male; diagnosis: benign hemangiopericytoma infraorbital left; size 1.5 x 1.5 x 1.5 cm.
  • The slow and painless growth carries the danger of a clinically wrong diagnosis and thus delayed therapy.
  • The histological diagnosis of hemangiopericytoma is determined by biopsy.
  • The therapy of choice is the complete tumour-resection with a safety margin of 1 cm.
  • [MeSH-major] Eyelid Neoplasms / diagnosis. Head and Neck Neoplasms / diagnosis. Hemangiopericytoma / diagnosis. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Neoplasm Invasiveness. Neoplasms, Multiple Primary / diagnosis. Neoplasms, Multiple Primary / pathology. Neoplasms, Multiple Primary / surgery. Orbit / pathology. Orbital Neoplasms / diagnosis. Orbital Neoplasms / pathology. Orbital Neoplasms / surgery. Reoperation. Tomography, X-Ray Computed

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  • (PMID = 16220316.001).
  • [ISSN] 1432-9417
  • [Journal-full-title] Mund-, Kiefer- und Gesichtschirurgie : MKG
  • [ISO-abbreviation] Mund Kiefer Gesichtschir
  • [Language] ger
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Germany
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29. Meli GA, Meli L, Chiaramonte R, Riva G, Pero G: Osteoblastoma of the orbit. A case report and review of the literature. Neuroradiol J; 2008 Feb 18;21(1):71-6
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  • [Title] Osteoblastoma of the orbit. A case report and review of the literature.
  • We describe a case of benign orbital tumour involving the frontal sinus and ethmoidal cells.
  • CT findings were typical of "bone tumour of the orbit", histological analysis yielded a diagnosis of benign osteoblastoma.
  • The orbit is rarely involved by bone tumours, but all bone tumours may theoretically involve the orbit, often making it difficult to establish the right differential diagnosis by imaging.
  • Even though many literature reports suggest CT is the landmark in bone tumour diagnosis, we think it should always be accompanied by MRI.
  • MRI is known to overestimate local staging, but its contribution to differential diagnosis among various tumours may be decisive.

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  • (PMID = 24256752.001).
  • [ISSN] 1971-4009
  • [Journal-full-title] The neuroradiology journal
  • [ISO-abbreviation] Neuroradiol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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30. Rizvi SA, Gupta Y, Gupta M: Surgical treatment and histopathological analysis of proptosis. Nepal J Ophthalmol; 2010 Jan-Jun;2(1):31-4
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  • INTRODUCTION: Inflammations and tumors of the orbit and para-orbital regions may present as proptosis.
  • MATERIALS AND METHODS: In a retrospective study, 25 cases of proptosis due to orbital and paraorbital tumours were analyzed in relation to their age, sex, and clinical and histopathological profiles.
  • According to location and type of tumour, different surgical options like anterior orbitotomy, lateral orbitotomy and medial orbitotomy were considered.
  • Primary orbital tumors were encountered in 15 cases (60%) and para-orbital in 10 (40%).
  • Of 15 primary orbital tumors, 7 (46.66%) were excised by lateral orbitotomy, another 7 (46.66%) were approached via anterior orbitotomy, whereas 1 (6.67%) was removed by medial orbitotomy.
  • Pediatric orbital tumors were quite common {7 (46.66%)}.
  • The most common benign adult tumor found in our study was pleomorphic adenoma of the lacrimal gland {3 (20%)}.
  • Proptosis due to primary orbital tumors is more common than para-orbital tumors.
  • Early diagnosis and timely surgical intervention provide good functional and cosmetic results.
  • [MeSH-major] Exophthalmos / surgery. Eye Neoplasms / pathology. Ophthalmologic Surgical Procedures / methods. Orbital Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Biopsy. Child. Child, Preschool. Diagnosis, Differential. Humans. Infant. Infant, Newborn. Middle Aged. Retrospective Studies. Treatment Outcome. Young Adult

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  • (PMID = 21141324.001).
  • [ISSN] 2072-6805
  • [Journal-full-title] Nepalese journal of ophthalmology : a biannual peer-reviewed academic journal of the Nepal Ophthalmic Society : NEPJOPH
  • [ISO-abbreviation] Nepal J Ophthalmol
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Nepal
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31. Maheshwari R, Thool A: Orbital cavernous hemangioma of childhood. Indian J Ophthalmol; 2007 Jul-Aug;55(4):313-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Orbital cavernous hemangioma of childhood.
  • Ocular and orbital tumors, both benign and malignant, occur relatively frequently in infants and children.
  • Benign masses are much more common than malignant in the orbital region.
  • However, childhood tumors show great variability and it is difficult to differentiate benign from malignant lesions.
  • Cavernous hemangioma is the most common benign neoplasm of the orbit in adults.
  • We report a case of orbital cavernous hemangioma in a four-year-old girl presenting as unilateral painless proptosis.
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 17595488.001).
  • [ISSN] 0301-4738
  • [Journal-full-title] Indian journal of ophthalmology
  • [ISO-abbreviation] Indian J Ophthalmol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
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32. Kashyap S, Pushker N, Meel R, Sen S, Bajaj MS, Khuriajam N, Mehta M, Chawla B: Orbital schwannoma with cystic degeneration. Clin Exp Ophthalmol; 2009 Apr;37(3):293-8
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  • [Title] Orbital schwannoma with cystic degeneration.
  • BACKGROUND: Schwannoma is a benign, slowly growing, painless, peripheral nerve sheath tumour that is uncommon in orbit.
  • Extensive cystic change in orbital schwannoma is quite rare.
  • We conducted this study to analyse the cases of orbital schwannoma, which were predominantly cystic and describe their clinical, imaging and histopathological features.
  • METHOD: A retrospective analysis of histopathology records of all the orbital tumours operated between 1993 and 2008 was undertaken at a tertiary care referral centre in northern India.
  • RESULTS: A total of 600 specimens of orbital tumours were received during the study period.
  • We found 39 cases of orbital schwannoma.
  • The radiological picture was quite variable resulting in a primary diagnosis of combined venous-lymphatic vascular malformation in 2, lacrimal gland tumour in 2, dermoid cyst in 1, hydatid cyst in 2 and schwannoma in 5 cases.
  • CONCLUSION: Orbital schwannoma is a great masquerader in the orbit.
  • Cystic schwannoma constituted 41% of all orbital schwannomas in our series.
  • To the best of our knowledge, this is the largest case series of orbital cystic schwannomas.
  • [MeSH-major] Cysts / pathology. Neurilemmoma / pathology. Orbital Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Diagnosis, Differential. Exophthalmos / etiology. Female. Humans. India. Male. Middle Aged. Retrospective Studies. Vision, Low

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  • (PMID = 19472538.001).
  • [ISSN] 1442-9071
  • [Journal-full-title] Clinical & experimental ophthalmology
  • [ISO-abbreviation] Clin. Experiment. Ophthalmol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Australia
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33. Dallaudiere B, Benayoun Y, Boncoeur-Martel M, Robert P, Adenis J, Maubon A: [Imaging features of cavernous hemangiomas of the orbit]. J Radiol; 2009 Sep;90(9 Pt 1):1039-45
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  • [Title] [Imaging features of cavernous hemangiomas of the orbit].
  • Cavernous hemangioma is the most frequent benign tumor of the orbit.
  • The clinical presentation is that of a slowly progressive intra-orbital mass with variable degree of exophthalmos.
  • CT typically demonstrates the presence of a well defined oval or rounded shaped mass but MRI provides superior evaluation of the orbit.
  • The tumor is intra-conal in 80% of cases and usually shows T1W hypo-isointensity, T2W hyperintensity and heterogeneous contrast enhancement that becomes more homogeneous on delayed imaging (5 minutes).
  • [MeSH-major] Hemangioma, Cavernous / diagnosis. Orbital Neoplasms / diagnosis

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  • (PMID = 19752807.001).
  • [ISSN] 0221-0363
  • [Journal-full-title] Journal de radiologie
  • [ISO-abbreviation] J Radiol
  • [Language] fre
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] France
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34. Subramanian N, Rambhatia S, Mahesh L, Menon SV, Krishnakumar S, Biswas J, Noronha OV: Cystic schwannoma of the orbit-a case series. Orbit; 2005 Jun;24(2):125-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Cystic schwannoma of the orbit-a case series.
  • A schwannoma is an uncommon benign orbital tumor that arises from Schwann cells in the peripheral nervous system.
  • Clinical examination alone is inadequate for the diagnosis.
  • Radiological examination, like computed tomography (CT) scans, can help in the diagnosis; however, the diagnosis can only be confirmed by histopathological examination (HPE) after excision biopsy.
  • Here, the authors report four cases of orbital schwannoma with cystic degeneration that presented with proptosis and decreased vision.
  • The histopathological examination was diagnostic for orbital schwannoma with cystic degeneration.
  • Schwannoma should be included in the differential diagnosis of cystic orbital lesions.
  • [MeSH-major] Blepharoptosis / etiology. Neurilemmoma / pathology. Orbital Neoplasms / pathology. Vision Disorders / etiology

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  • (PMID = 16191802.001).
  • [ISSN] 0167-6830
  • [Journal-full-title] Orbit (Amsterdam, Netherlands)
  • [ISO-abbreviation] Orbit
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Netherlands
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